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AIWAAGDTAGVATVVRTLRSAPRPPGAAMVVAPDGSVSGSVSGGCVEGAVYELAAEVAQTGIPRLEHYGV SDDTAFAVGLTCGGIIDVFVEPVSRATFPELGELADDIGAQRPVAIATVIAHPDERRVGRRLVIRPDTKS PVTGSLGSARADAAVIDDARGLLAVGRSEILEYGPDGQRRGEGMEVFVSSHAPRPRMLVFGAIDFAAALA RQGSFLGYRVTVCDARAVFATPARFPTADDVVVAWPHRYLAAQAEAGGIDERTVICVLTHDPKFDVPVLE VALRLGVGYVGAMGSRKTHDDRMDRLRAAGLTDAELSRLSSPIGLDLGARTPEETAVSIAADIIARRWGG GGRPLADIAGRIHHDAQVAGEFKDYLTRH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0376c | - | - | 100% (380) | hypothetical protein Rv0376c |
| M. tuberculosis H37Rv | Rv0372c | - | 5e-18 | 29.55% (264) | hypothetical protein Rv0372c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0383c | - | 0.0 | 100.00% (380) | hypothetical protein Mb0383c |
| M. gilvum PYR-GCK | Mflv_1574 | - | 1e-156 | 74.32% (366) | hypothetical protein Mflv_1574 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2924c | - | 2e-86 | 50.00% (366) | hypothetical protein MAB_2924c |
| M. marinum M | MMAR_0654 | - | 1e-179 | 83.73% (375) | hypothetical protein MMAR_0654 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_0743 | - | 1e-165 | 78.42% (366) | xanthine dehydrogenase |
| M. thermoresistible (build 8) | TH_0173 | - | 1e-168 | 76.94% (386) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0114 | - | 3e-17 | 30.83% (266) | hypothetical protein MUL_0114 |
| M. vanbaalenii PYR-1 | Mvan_5182 | - | 1e-154 | 72.83% (368) | hypothetical protein Mvan_5182 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1574|M.gilvum_PYR-GCK --------------MWEAGGTAGLSTVVRTMKSAPRPPGAAMVVSPDGTV
Mvan_5182|M.vanbaalenii_PYR-1 ----MRDVLDELLAVWRSGETAGLSTVVRTMQSAPRPPGAAMVVGPDGAV
Rv0376c|M.tuberculosis_H37Rv ------------MAIWAAGDTAGVATVVRTLRSAPRPPGAAMVVAPDGSV
Mb0383c|M.bovis_AF2122/97 ------------MAIWAAGDTAGVATVVRTLRSAPRPPGAAMVVAPDGSV
MMAR_0654|M.marinum_M ----MRDVLTDLITIWRAGDTAGLATVVRTLRSAPRPPGASMVVAPDGSV
MSMEG_0743|M.smegmatis_MC2_155 MLGGVRDVLGTLSAVWESGGTAGVGTVVRTFRSAPRPAGASMVVAPDGTV
TH_0173|M.thermoresistible__bu -------VLDGLLPVWRSGDTAGLATVVRTFRSAPRLPGAAMVVAPDGTV
MAB_2924c|M.abscessus_ATCC_199 ----MKDILRDLIAVLEGGGTAALARVVEVSGAVPREPGAAMIVPADGPV
MUL_0114|M.ulcerans_Agy99 ---MQMTISERAAQLLAARTPFVHATVVRAQPPTSAYPGDEAILLPDGTI
: . . . **.. ... .* :: .**.:
Mflv_1574|M.gilvum_PYR-GCK AGSVSGGCVEGAVYETANEVITGGAPHLQRYGVSDDDAFSVGLTCGGIID
Mvan_5182|M.vanbaalenii_PYR-1 AGSVSGGCVEAAVYEVANDVVASGVPELQRYGISDDDAFTVGLTCGGTID
Rv0376c|M.tuberculosis_H37Rv SGSVSGGCVEGAVYELAAEVAQTGIPRLEHYGVSDDTAFAVGLTCGGIID
Mb0383c|M.bovis_AF2122/97 SGSVSGGCVEGAVYELAAEVAQTGIPRLEHYGVSDDTAFAVGLTCGGIID
MMAR_0654|M.marinum_M SGSVSGGCVEGAVYESAGEVTRTGIPRLERYGVSDDDAFAVGLTCGGIID
MSMEG_0743|M.smegmatis_MC2_155 SGSVSGGCVEGAVYDLATEVVATGTPVLQRYGVSDDDAFEVGLTCGGILD
TH_0173|M.thermoresistible__bu SGSVSGGCVEGAVYELATEVIQTGRPRLQRYGVSDDDAFSVGLTCGGTLD
MAB_2924c|M.abscessus_ATCC_199 VGSLSGGCVEAAVIETAREVLAIGLCVSERFGIDDG--IAPGLTCGGEIE
MUL_0114|M.ulcerans_Agy99 EGFVGGQCAQNSVRKAALGVLQAGESVLLRVLPDGDVHFPEAPGACVVVN
* :.* *.: :* . * * * : ... : . . ::
Mflv_1574|M.gilvum_PYR-GCK IFTEPVSRNTFPQLRDVATAIAEHRAVAVATVIAHPDPARVGRRIIVGTD
Mvan_5182|M.vanbaalenii_PYR-1 VFTEPVSRETFPQLQQVADDIAAHRPVAVATVIVHPDPKRVGLRLVVGRD
Rv0376c|M.tuberculosis_H37Rv VFVEPVSRATFPELGELADDIGAQRPVAIATVIAHPDERRVGRRLVIRPD
Mb0383c|M.bovis_AF2122/97 VFVEPVSRATFPELGELADDIGAQRPVAIATVIAHPDERRVGRRLVIRPD
MMAR_0654|M.marinum_M IFIEAVSPATFPELVAVAEDIAAHVPVAVATVIAHPDPQWVGRRLVVRTD
MSMEG_0743|M.smegmatis_MC2_155 VFVEPVSQKTFPQLGAIRDDIEAQRPVAVATVITHPDAQWIGRRLVVHTD
TH_0173|M.thermoresistible__bu VFVEAVSQNSFPELADLVGDIEAHRPVATATVIAHSDPGWVGRRLVLRPD
MAB_2924c|M.abscessus_ATCC_199 VVTEHIGAERFPLLRELRSALVAGEPMGLVSTLSG-----IPDWALVR--
MUL_0114|M.ulcerans_Agy99 PCLS----------------------------------------------
.
Mflv_1574|M.gilvum_PYR-GCK SR----QGSVGSPRADDAVADDARGLLLAGRSAVLSYGPDGQRQDAGMEV
Mvan_5182|M.vanbaalenii_PYR-1 SR----HGSLGSSRTDDAVTDDARGLLLAGRSGVLTYGADGQRQESGMEV
Rv0376c|M.tuberculosis_H37Rv TK-SPVTGSLGSARADAAVIDDARGLLAVGRSEILEYGPDGQRRGEGMEV
Mb0383c|M.bovis_AF2122/97 TK-SPVTGSLGSARADAAVIDDARGLLAVGRSEILEYGPDGQRRGEGMEV
MMAR_0654|M.marinum_M PS-RPTAGSLGSVRADAAVTDDARGLLALGRSEILKYGPDGQRRGEGMEI
MSMEG_0743|M.smegmatis_MC2_155 ----EVAGSLGSSRADAAVTDDARGLLAAGRSEVLTYGPDGQRRGEGMEV
TH_0173|M.thermoresistible__bu HEDAPVSGSLGSPRADAAVTDDARGLLAAGRTEVLTYGPDGQRRGEGMEV
MAB_2924c|M.abscessus_ATCC_199 ---------AGEPAPWPQIEGDIVSLIRAGRSAVAGADRCEPDQSDLPRV
MUL_0114|M.ulcerans_Agy99 --------------------------------------------GGSLEI
.:
Mflv_1574|M.gilvum_PYR-GCK FVSSYAPRPRMLVFGAIDFAAALAHQAAFLGYRVTVCDARPVFATEARFP
Mvan_5182|M.vanbaalenii_PYR-1 FVCSHAPRPKMLVFGAIDFASALARQATFLGYRVTVCDARPVFATAARFP
Rv0376c|M.tuberculosis_H37Rv FVSSHAPRPRMLVFGAIDFAAALARQGSFLGYRVTVCDARAVFATPARFP
Mb0383c|M.bovis_AF2122/97 FVSSHAPRPRMLVFGAIDFAAALARQGSFLGYRVTVCDARAVFATPARFP
MMAR_0654|M.marinum_M FVSSFAPRPRMLVFGAIDFAAALARQGSFLGYRVTVCDARAVFATRARFP
MSMEG_0743|M.smegmatis_MC2_155 FVSSYAPRPRMLVFGAIDFAAAVAQQGAFLGYRVTVCDARPVFATTARFP
TH_0173|M.thermoresistible__bu FVASYAPRPRMLVFGAIDFAAAVAQQASFLGYRVTVCDARAVFATPARFP
MAB_2924c|M.abscessus_ATCC_199 FVQAFAAPPRMILAGANAFVRALSRTGSQLGYRVTVVDAREVFATPAHFP
MUL_0114|M.ulcerans_Agy99 FLTPQLPAPLVRIYGATPIAEALIEVCGVLGY-----DARRDSDPVGAAA
*: . . * : : ** :. *: . *** *** . . .
Mflv_1574|M.gilvum_PYR-GCK AAEEVVVDWPHRYLAAQADLGLIDARTAICVLTHDPKFDVPVLEVALRLP
Mvan_5182|M.vanbaalenii_PYR-1 AAEEVVVDWPDRYLRAQAEQGEIDSRTAVCVLTHDPKFDVPVLEVALRLP
Rv0376c|M.tuberculosis_H37Rv TADDVVVAWPHRYLAAQAEAGGIDERTVICVLTHDPKFDVPVLEVALRLG
Mb0383c|M.bovis_AF2122/97 TADDVVVAWPHRYLAAQAEAGGIDERTVICVLTHDPKFDVPVLEVALRLG
MMAR_0654|M.marinum_M TADEVVVEWPSRYLAAEVQAGAIDERTVICVLTHDPKFDVPVLEVALRLP
MSMEG_0743|M.smegmatis_MC2_155 TADEVVVDWPHRYLAAQAEAGAIDARTVVCVLTHDPKFDVPLLEVALRLP
TH_0173|M.thermoresistible__bu TADEVVVEWPHRYLAAQAEAGAVDSRTAICVLTHDPKFDVPLLEVALRLP
MAB_2924c|M.abscessus_ATCC_199 YADEVVVDWPHRYLRAEAAGGRVDARTVVCVLTHDPKFDVPMLAAALTVA
MUL_0114|M.ulcerans_Agy99 LPTAVVIAS----------HGGPEAENIRAALDNG---------------
. **: * : .. ..* :.
Mflv_1574|M.gilvum_PYR-GCK DAGYIGVMGSRRTHEDRMSRLREAGLTETELARLASPIGLDLGARTPEET
Mvan_5182|M.vanbaalenii_PYR-1 ELDYIGVMGSRRTHHDRVRRLREAGLTDKELARLSSPIGLDLGARTPEET
Rv0376c|M.tuberculosis_H37Rv -VGYVGAMGSRKTHDDRMDRLRAAGLTDAELSRLSSPIGLDLGARTPEET
Mb0383c|M.bovis_AF2122/97 -VGYVGAMGSRKTHDDRMDRLRAAGLTDAELSRLSSPIGLDLGARTPEET
MMAR_0654|M.marinum_M RIGYVGAMGSRQTHDDRMSRLRAAGLTDAELSQLSSPIGLDLGARTPEET
MSMEG_0743|M.smegmatis_MC2_155 DIAYIGAMGSRRTHEDRLARLREAGLTEEELARLSSPIGLDLGGRTPEET
TH_0173|M.thermoresistible__bu EVGYIGAMGSRRTHEDRLERLRQAGLTDVELSRLSSPIGLDLGGRTPEET
MAB_2924c|M.abscessus_ATCC_199 PVAFVGALGSRRTHTDRMARLREQGVTDDQLGRLRSPLGLDLNARTPEET
MUL_0114|M.ulcerans_Agy99 -VGYIGLVASKVRGAAVLDSLG---LSATERARIRTPVGLAIGAKTPAEI
::* :.*: : * :: : .:: :*:** :..:** *
Mflv_1574|M.gilvum_PYR-GCK AVSIAAEIIARRWGGGGRPLTETDGRIHHEA-----------------
Mvan_5182|M.vanbaalenii_PYR-1 AVSIAAEIIARRWGGDGRPLSQTDGRIHHPA-----------------
Rv0376c|M.tuberculosis_H37Rv AVSIAADIIARRWGGGGRPLADIAGRIHHDAQVAGEFKDYLTRH----
Mb0383c|M.bovis_AF2122/97 AVSIAADIIARRWGGGGRPLADIAGRIHHDAQVAGEFKDYLTRH----
MMAR_0654|M.marinum_M AVSIAADIIARRWGGGGRPLAETSGRIHRDLQVADDFEASAG------
MSMEG_0743|M.smegmatis_MC2_155 AVSIAAEIIAKRWGGEGRPLAETGGRIHH---ELGEHESAPAS-----
TH_0173|M.thermoresistible__bu AVSIAAEIIARQWGGTGRPLSETGGRIHHGGDPMKDHTSELSDPLSRY
MAB_2924c|M.abscessus_ATCC_199 AISIAAQIIAETSGGSGRPLSDIDGPIHR-------------------
MUL_0114|M.ulcerans_Agy99 AVAIAAEIIAAVRAGGGAGPRRWMRLPPRRWTRCAG------------
*::***:*** .* * :