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MTEAYIVDAVRTAVGKRGGGLAGVHPADMAAHVIKTLVGRHDIDPAAIDDVILGCLDNIGSQAGDIARTA ALAAGLPESVPGVTVDRQCGSAQQAVHFAAQAVMSGTCDLIVAGGVQKMSQFPILCAFEAGEPFGSSDPW TGCEGWQARYGDQEISQFRGAEMIASQWNLSREDNERFALASHQRAVTAISEGRFTREIIPFAGVSVDEG PRANTSLEKMAGLPTLVEGGVLTAAVASQISDGAAALLIASQDAVDRFGLNPRARVHHMSVRGSDPVMML TAPIPATQHALKRTGLSIDDIDTVEINEAFAPVVLAWLAELGADPVKVNPNGGAIALGHPIGCTGARLMT SMLHELERTGGRFGLQTMCEGGGQANVTIIERL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_5069 | - | - | 100% (383) | acetyl-CoA acetyltransferase |
| M. avium 104 | MAV_0604 | - | e-149 | 69.25% (387) | acetyl-CoA acetyltransferase |
| M. avium 104 | MAV_1276 | - | e-109 | 52.56% (390) | acetyl-CoA acetyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3586c | fadA6 | 1e-149 | 68.99% (387) | acetyl-CoA acetyltransferase |
| M. gilvum PYR-GCK | Mflv_1484 | - | 1e-149 | 68.65% (386) | acetyl-CoA acetyltransferase |
| M. tuberculosis H37Rv | Rv3556c | fadA6 | 1e-149 | 68.99% (387) | acetyl-CoA acetyltransferase |
| M. leprae Br4923 | MLBr_02162 | fadA | 3e-70 | 40.44% (413) | acetyl-CoA acetyltransferase |
| M. abscessus ATCC 19977 | MAB_0600 | - | 1e-145 | 67.62% (383) | acetyl-CoA acetyltransferase |
| M. marinum M | MMAR_5045 | fadA6_1 | 1e-150 | 69.77% (387) | acetyl-CoA acetyltransferase FadA6_1 |
| M. smegmatis MC2 155 | MSMEG_6008 | - | 1e-149 | 67.62% (383) | acetyl-CoA acetyltransferase |
| M. thermoresistible (build 8) | TH_0166 | fadA6 | 0.0 | 87.21% (383) | PROBABLE ACETYL-CoA ACETYLTRANSFERASE FADA6 |
| M. ulcerans Agy99 | MUL_4119 | fadA6_1 | 1e-149 | 69.51% (387) | acetyl-CoA acetyltransferase |
| M. vanbaalenii PYR-1 | Mvan_5282 | - | 1e-147 | 68.15% (383) | acetyl-CoA acetyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_5069|M.avium_104 ---MTEAYIVDAVRTAVGK-RGGGLAGVHPADMAAHVIKTLVGRH-DIDP
TH_0166|M.thermoresistible__bu -MAMTEAYIVDAVRTPVGK-RNGGLSGAHPADMAAHVIKTLVGRH-DFDP
Mb3586c|M.bovis_AF2122/97 ---MTEAYVIDAVRTAVGK-RGGALAGIHPVDLGALAWRGLLDRT-DIDP
Rv3556c|M.tuberculosis_H37Rv ---MTEAYVIDAVRTAVGK-RGGALAGIHPVDLGALAWRGLLDRT-DIDP
MMAR_5045|M.marinum_M ---MPEAYVIDAVRTAVGK-RGGALAGVHPVDLGALGWRGLLDRV-DVDP
MUL_4119|M.ulcerans_Agy99 ---MPEAYVIDAVRTAVGK-RGGALAGVHPVDLGALGWRGLLDRV-DVDP
Mflv_1484|M.gilvum_PYR-GCK MAVASEAYVIDAVRTAVGK-RNGSLAGVHPVDLGAAAWRGLFERN-DVDP
Mvan_5282|M.vanbaalenii_PYR-1 ---MAEAYVIDAVRTAIGK-RNGSLAGMHPVDLGAAGWRGLFARN-DVDP
MSMEG_6008|M.smegmatis_MC2_155 ---MPEAYIIDAVRTPVGK-KNGSLAQVHPIDLGVHVFRSIFDRV-DVDP
MAB_0600|M.abscessus_ATCC_1997 ---MSEAYIIDAVRTAVGK-RNGALSKVHPLDLGAATFKGLFDRV-DVDP
MLBr_02162|M.leprae_Br4923 --MSEEAFIYEAIRTPRGKQKNGSLHEVKPVSLVVGLVEELRKRNPDLDE
**:: :*:**. ** :.*.* :* .: . . : * *.*
MAV_5069|M.avium_104 AAIDDVILGCLDNIGSQAGDIARTAALAAGLPESVPGVTVDRQCGSAQQA
TH_0166|M.thermoresistible__bu AAIDDVIFGCLDNIGSQAGDIARTAALAAGLPESVPGVTIDRQCGSAQQA
Mb3586c|M.bovis_AF2122/97 AAVDDVIAGCVDAIGGQAGNIARLSWLAAGYPEEVPGVTVDRQCGSSQQA
Rv3556c|M.tuberculosis_H37Rv AAVDDVIAGCVDAIGGQAGNIARLSWLAAGYPEEVPGVTVDRQCGSSQQA
MMAR_5045|M.marinum_M AAVDDVIAGCVDAIGGQAGNIARLSWLAAGYPEEVPGVTVDRQCGSSQQA
MUL_4119|M.ulcerans_Agy99 AAVDDVIAGCVDAIGGQAGNIARLSWLAAGYPEEVPGVTVDRQCGSSQQA
Mflv_1484|M.gilvum_PYR-GCK GAVDDVIAGCVDAIGPQAGNIARLSWLAAGFPEEVPGVTVDRQCGSSQQA
Mvan_5282|M.vanbaalenii_PYR-1 GAVDDVIAGCVDAIGPQAGNIARLSWLAAGYPEEVPGVTVDRQCGSSQQA
MSMEG_6008|M.smegmatis_MC2_155 GAVDDVIVGCVDAIGGQAGNIGRNAWLAAGYPEEVPGVTVDRQCGSSQQA
MAB_0600|M.abscessus_ATCC_1997 DAIDDVYMGVLDAIGGQAGNAGRLAWLAGGYPEEVPGATVDRQCGSSQQA
MLBr_02162|M.leprae_Br4923 NLISDVILGCVSPVGDQGGDIARATVLAAGLPVTAGGVQLNRFCASGLEA
:.** * :. :* *.*: .* : **.* * . *. ::* *.*. :*
MAV_5069|M.avium_104 VHFAAQAVMSGTCDLIVAGGVQKMSQFPILCAFEAGEPFGSSDPWTGCEG
TH_0166|M.thermoresistible__bu VHFAAQGVMSGTVDLIVAGGVQKMSQFPILSAFAAGEPYGATDPWTGCEG
Mb3586c|M.bovis_AF2122/97 ISFGAQAIMSGTADVIVAGGVQNMSQIPISSAMTVGEQFGFTSPTNESKQ
Rv3556c|M.tuberculosis_H37Rv ISFGAQAIMSGTADVIVAGGVQNMSQIPISSAMTVGEQFGFTSPTNESKQ
MMAR_5045|M.marinum_M ISFGAQAIMSGTADLIVAGGMQNMSQIPISSAMIVGEQFGFSSPTNESKQ
MUL_4119|M.ulcerans_Agy99 ISFGAQAIMSGTADLIVAGGMQNMSQIPISSAMIVGEQFGFSSPTNESKQ
Mflv_1484|M.gilvum_PYR-GCK ISFGAQAIMSGTADLIVAGGMQNMSQIPISSAMTVAEQFGFTSPTNESKS
Mvan_5282|M.vanbaalenii_PYR-1 ISFGAQAILSGTADLIVAGGMQNMSQIPISSAMIVGEQFGFTSPTNESKS
MSMEG_6008|M.smegmatis_MC2_155 ISFGAQAIMSGTADIILAGGMQNMSWVPISSAMIVGKELGFSTPTAESEY
MAB_0600|M.abscessus_ATCC_1997 ISFAAQAVMSGTADLIVAGGFQNMSQIPISAAMLVGKEYGFTSPTAESEG
MLBr_02162|M.leprae_Br4923 VNTAAQKVRSGWDDLVLAGGVESMSRVPMGSD---GGAMGLDPATN----
: .** : ** *:::***.:.** .*: . . * .
MAV_5069|M.avium_104 WQARYGDQEISQFRGAEMIASQWNLSREDNERFALASHQRAVTAISEGRF
TH_0166|M.thermoresistible__bu WQARYGDQEISQFRGAEMIAEHWKLSREDNEKFALESHRRAVAAIEAGYF
Mb3586c|M.bovis_AF2122/97 WLHRYGDQEISQFRGSELIAEKWNLSREEMERYSLTSHERAFAAIRAGHF
Rv3556c|M.tuberculosis_H37Rv WLHRYGDQEISQFRGSELIAEKWNLSREEMERYSLTSHERAFAAIRAGHF
MMAR_5045|M.marinum_M WLHRYGDQEISQFRGSEMIAEKWNLSREEMEQYALTSHARAFAAIRGGRF
MUL_4119|M.ulcerans_Agy99 WLHRYGDQEISQFRGSEMIAEKWNLSREEMEQYALTSHARAFAAIRGGRF
Mflv_1484|M.gilvum_PYR-GCK WLHRYGDQEISQFRGSELIAEKWNLSREEMEQYALMSHHRAQAAIRAGHF
Mvan_5282|M.vanbaalenii_PYR-1 WLHRYGDQEISQFRGAEMIAEKWDISREDMEQFALTSNQRAQAAIRAGHF
MSMEG_6008|M.smegmatis_MC2_155 WRHRYGDQEISQFRGSELIAERWDISREEMEQFALSSHQRAFAAIRAGHF
MAB_0600|M.abscessus_ATCC_1997 WLHRYGDQEISQFRGAEMIAEKWDISREEMERFALSSHEKAFAAIRNGHF
MLBr_02162|M.leprae_Br4923 ----YDVMFVPQGIGADLIATIEGFSRDDVDVYALRSQEKAAAAWSGGYF
*. :.* *:::** :**:: : ::* *: :* :* * *
MAV_5069|M.avium_104 TREIIPFA----GVSVD--EGPRANTSLEKMAGLPTLVEG----------
TH_0166|M.thermoresistible__bu DKEITPYA----DATVD--EGPRPDTSLEKMASLPTLIEG----------
Mb3586c|M.bovis_AF2122/97 ENEIITVETESGPFRVD--EGPR-ESSLEKMAGLQPLVEG----------
Rv3556c|M.tuberculosis_H37Rv ENEIITVETESGPFRVD--EGPR-ESSLEKMAGLQPLVEG----------
MMAR_5045|M.marinum_M DNEILSVETESGPFRVD--EGPR-ESSLEKMAGLKTLVEG----------
MUL_4119|M.ulcerans_Agy99 DNEILSVETESGPFRVD--EGPR-ESSLEKMAGLKTLVEG----------
Mflv_1484|M.gilvum_PYR-GCK ENEIIPVQTDGAGFATD--EGPR-DTSLEKMAGLKTLVEG----------
Mvan_5282|M.vanbaalenii_PYR-1 ENEIIDVD----GFRVD--ECPR-ETTLEKMAGLKTLVDG----------
MSMEG_6008|M.smegmatis_MC2_155 DNEIVPVG----DFGVD--EGPR-ETTLEKMAALQPLVEG----------
MAB_0600|M.abscessus_ATCC_1997 DNEIIPVG----DFRVD--EGPR-ESTLEKLASLNPLVEG----------
MLBr_02162|M.leprae_Br4923 AKSVVPVRDQNGLLILDHDEHMRPDTSKEGLAKLKPAFEGLAAMGGFDDV
..: * * * ::: * :* * . .:*
MAV_5069|M.avium_104 ------------GVLTAAVASQISDGAAALLIASQDAVDRFGLNPRARVH
TH_0166|M.thermoresistible__bu ------------GVLTAAVASQISDGAAALLVASKDAVDRFNLTPRARIH
Mb3586c|M.bovis_AF2122/97 ------------GRLTAAMASQISDGASAVLLASERAVKDHGLRPRARIH
Rv3556c|M.tuberculosis_H37Rv ------------GRLTAAMASQISDGASAVLLASERAVKDHGLRPRARIH
MMAR_5045|M.marinum_M ------------GRLTAAMASQISDGASAVLLASEQAVKDHGLTPRARIH
MUL_4119|M.ulcerans_Agy99 ------------GRLTAAMASQISDGASAVLLASEQAVKDHGLTPRARIH
Mflv_1484|M.gilvum_PYR-GCK ------------GRLTAAMASQISDGASAVLLASEDAVKAHGLKPRARIH
Mvan_5282|M.vanbaalenii_PYR-1 ------------GRLTAAMASQISDGASAVLLASENAVKVHNLKPRARIH
MSMEG_6008|M.smegmatis_MC2_155 ------------GRLTAALASQISDGASAVLLASEQAVKEHNLKPRARIH
MAB_0600|M.abscessus_ATCC_1997 ------------GRLTAALASQISDGGSATLVASERAVKAHGLTPRARVH
MLBr_02162|M.leprae_Br4923 ALQKYHWVEKINHVHTGGNSSGIVDGAALVMIGSEAVGKSQGLTPRARMV
*.. :* * **.: ::.*: . . .* ****:
MAV_5069|M.avium_104 HMSVRGSDPVMMLTAPIPATQHALKRTGLSIDDIDTVEINEAFAPVVLAW
TH_0166|M.thermoresistible__bu HMSVRGADPVMMLTAPIPATQHALKRAGMSIDDIDAVEINEAFAPVVLAW
Mb3586c|M.bovis_AF2122/97 HISARAADPVFMLTGPIPATRYALDKTGLAIDDIDTVEINEAFAPVVMAW
Rv3556c|M.tuberculosis_H37Rv HISARAADPVFMLTGPIPATRYALDKTGLAIDDIDTVEINEAFAPVVMAW
MMAR_5045|M.marinum_M HISARAADPVFMLTGPIPATRHALEKTGLSIDDIATVEINEAFAPVVLAW
MUL_4119|M.ulcerans_Agy99 HISARAADPVFMLTGPIPATRHALEKTGLSIDDIATVEINEAFAPVVLAW
Mflv_1484|M.gilvum_PYR-GCK HISARGADPVFMLTGPIPATRYALDKTGLTIDDIDTVEINEAFAPVVQAW
Mvan_5282|M.vanbaalenii_PYR-1 HISARGADPVFMLTGPIPATQYALDRAGLTIEDIDTVEINEAFAPVVQAW
MSMEG_6008|M.smegmatis_MC2_155 HISARGADPVMMLTGPIPATEYALKKTGLSIDDIDTVEINEAFAPVVLAW
MAB_0600|M.abscessus_ATCC_1997 HISARGDDPVFMLTGPIPATRYALEKTGLTMDDIDVVEINEAFAPVVLAW
MLBr_02162|M.leprae_Br4923 ATATSGADPVIMLTGPTPATRKVLDRAGLTVDDIDLFELNEAFASVVLKF
:. . ***:***.* ***. .*.::*::::** .*:*****.** :
MAV_5069|M.avium_104 LAELGADPVKVNPNGGAIALGHPIGCTGARLMTSMLHELERTGGRFGLQT
TH_0166|M.thermoresistible__bu LAELGADPARVNPNGGAIALGHPIGCTGARLMTSLLHHLERTGGRYGLQT
Mb3586c|M.bovis_AF2122/97 LKEIKADPAKVNPNGGAIALGHPLGATGAKLFTTMLGELERIGGRYGLQT
Rv3556c|M.tuberculosis_H37Rv LKEIKADPAKVNPNGGAIALGHPLGATGAKLFTTMLGELERIGGRYGLQT
MMAR_5045|M.marinum_M LKEIKADPEKVNPNGGAIALGHPLGATGAKLFTTMLNELDRVGGRYGLQT
MUL_4119|M.ulcerans_Agy99 LKEIKADPEKVNPNGGAIALGHPLGATGAKLFTTMLNELDRVGGRYGLHT
Mflv_1484|M.gilvum_PYR-GCK LKETKADPEKVNPSGGAIALGHPLGATGAKLFATMLNTLERTGGRYGLQT
Mvan_5282|M.vanbaalenii_PYR-1 LKETKADPEKVNPNGGAIALGHPLGATGAKLFATMLNTLERTGGRYGLQT
MSMEG_6008|M.smegmatis_MC2_155 IKDLKADPEKVNPNGGAIALGHPLGATGAKLFATMLNTLERTGGRYGLQT
MAB_0600|M.abscessus_ATCC_1997 AKELDVDLKKVNPNGGAMALGHPLGATGAKLFATMLNELERTGGRYGLQT
MLBr_02162|M.leprae_Br4923 QKDLNIPDEKLNVNGGAIAMGHPLGATGAMILGTMVDELERCNARRALVT
: ::* .***:*:***:*.*** :: ::: *:* ..* .* *
MAV_5069|M.avium_104 MCEGGGQANVTIIERL-
TH_0166|M.thermoresistible__bu MCEGGGQANVTIIERL-
Mb3586c|M.bovis_AF2122/97 MCEGGGTANVTIIERL-
Rv3556c|M.tuberculosis_H37Rv MCEGGGTANVTIIERL-
MMAR_5045|M.marinum_M MCEGGGTANVTIIERL-
MUL_4119|M.ulcerans_Agy99 MCEGGGTANVTIIERL-
Mflv_1484|M.gilvum_PYR-GCK MCEGGGTANVTIIERLS
Mvan_5282|M.vanbaalenii_PYR-1 MCEGGGTANVTIIERL-
MSMEG_6008|M.smegmatis_MC2_155 MCEGGGTANVTIIERL-
MAB_0600|M.abscessus_ATCC_1997 MCEGGGTANVTIIERL-
MLBr_02162|M.leprae_Br4923 LCIGAGMGVATIIERV-
:* *.* . .*****: