For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
PLSLSNRDQNSGHLFYNRRLRAATTRFSVRMKHDDRKQTAALALSMVLVAIAAGWMMLLNVLKPTGIVGD SAIIGDRDSGALYARIDGRLYPALNLTSARLATGTAGQPTWVKPAEIAKYPTGPLVGIPGAPAAMPVNRG AVSAWAVCDTAGRPRSADKPVVTSIAGPITGGGRATHLRDDAGLLVTFDGSTYVIWGGKRSQIDPTNRAV TLSLGLDPGVTSPIQISRALFDGLPATEPLRVPAVPEAGTPSTWVPGARVGSVLQAQTAGGGSQFYVLLP DGVQKISSFVADLLRSANSYGAAAPRVVTPDVLVHTPQVTSLPVEYYPAGRLNFVDTAADPTTCVSWEKA STDPQARVAVYNGRGLPVPPSMDSRIVRLVRDDRAPASVVATQVLVLPGAANFVTSTSGVITAESRESLF WVSGNGVRFGIANDEATLRALGLDPGAAVQAPWPLLRTFAAGPALSRDAALLARDTVPTLGQVAIVTTTA KAGA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3895c | - | - | 100% (495) | PROBABLE CONSERVED MEMBRANE PROTEIN |
| M. tuberculosis H37Rv | Rv1782 | - | 6e-86 | 40.70% (484) | hypothetical protein Rv1782 |
| M. tuberculosis H37Rv | Rv0283 | - | 4e-78 | 37.01% (489) | hypothetical protein Rv0283 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3925c | - | 0.0 | 99.80% (495) | hypothetical protein Mb3925c |
| M. gilvum PYR-GCK | Mflv_0328 | - | 4e-73 | 36.46% (480) | hypothetical protein Mflv_0328 |
| M. leprae Br4923 | MLBr_01544 | - | 2e-82 | 39.26% (484) | hypothetical protein MLBr_01544 |
| M. abscessus ATCC 19977 | MAB_3759c | - | 6e-69 | 36.69% (477) | hypothetical protein MAB_3759c |
| M. marinum M | MMAR_2664 | - | 4e-84 | 40.00% (485) | hypothetical protein MMAR_2664 |
| M. avium 104 | MAV_5285 | - | 0.0 | 86.44% (494) | hypothetical protein MAV_5285 |
| M. smegmatis MC2 155 | MSMEG_0616 | - | 4e-78 | 37.86% (486) | hypothetical protein MSMEG_0616 |
| M. thermoresistible (build 8) | TH_3503 | - | 2e-55 | 33.61% (485) | PUTATIVE protein of unknown function DUF690 |
| M. ulcerans Agy99 | MUL_3093 | - | 2e-83 | 39.59% (485) | hypothetical protein MUL_3093 |
| M. vanbaalenii PYR-1 | Mvan_0412 | - | 2e-75 | 37.20% (492) | hypothetical protein Mvan_0412 |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_3759c|M.abscessus_ATCC_199 ---------------------------MARQPTTRLQVSGYRFLVRRMEH
TH_3503|M.thermoresistible__bu --------------------------MAGFRLTTKVQVSGWRFLLRRVEH
Mflv_0328|M.gilvum_PYR-GCK MSGAD--GDRRSFTSRTPTNENPDRVSFRRGFVTRHQVSGWRFMVRRMAS
Mvan_0412|M.vanbaalenii_PYR-1 MSAPE--EERRSFASRTPTNGNPDRVTYRRGFVTRHQVTGWRFVMRRIAS
MSMEG_0616|M.smegmatis_MC2_155 MTGPVNPDDRRSFSSRTPVNENPDGVQYRRGFVTRHQVSGWRFVMRRIAS
Rv3895c|M.tuberculosis_H37Rv ---------------------------MPLSLSNRDQNSGHLFYNRRLRA
Mb3925c|M.bovis_AF2122/97 ---------------------------MPLSLSNRDQNSGHLFYNRRLRA
MAV_5285|M.avium_104 ---------------------------MPLSLSNRDQNSGHLFYNRRLRA
MMAR_2664|M.marinum_M ---------------MAEQGRGQRGSGYGLGLSTRTQVTGYQFLARRTAM
MUL_3093|M.ulcerans_Agy99 ---------------MAEQGRGQRGSGYGLGLSTRTQVTGYQFLARRTAM
MLBr_01544|M.leprae_Br4923 ---------------MAEESSGRRGSEYGLGLSTRTQVTGYQFLARRTAM
.: * :* * **
MAB_3759c|M.abscessus_ATCC_199 ALVRRDVRMIHDPMRSQSSSLMVGIVLATVVVAGCAILAFFRPNMPLGDQ
TH_3503|M.thermoresistible__bu AIVRRDTRMFDDPLQFYSRAVQAGIVISVLICLGAVLLAYFKPLGKRGGD
Mflv_0328|M.gilvum_PYR-GCK GVALHDTRMLVDPLRTQSRSVLVGALILVTGLIGCFLFSLIRPAGDVGTD
Mvan_0412|M.vanbaalenii_PYR-1 GVALHDTRMLVDPLRTQSRSVLVGALILVTGLIGCFLFSLIRPSGAAGTD
MSMEG_0616|M.smegmatis_MC2_155 GVALHDTRMLVDPLRTQSRAVLTGALILVTGLVGCFIFSLFRPGGVPGNN
Rv3895c|M.tuberculosis_H37Rv ATTRFSVRMKHD-DRKQTAALALSMVLVAIAAGWMMLLNVLKPTGIVGDS
Mb3925c|M.bovis_AF2122/97 ATTRFSVRMKHD-DRKQTAALALSMVLVAIAAGWMMLLNVLKPTGIVGDS
MAV_5285|M.avium_104 ATTRFSVRMKHD-DRKQTAALVLSMVLVAIASGWMMLLNVLKPTGIVGDS
MMAR_2664|M.marinum_M ALTRWRVRMEIEPGRRQTLAVVASVSAALVICLGSLLWSFISPSGQINDS
MUL_3093|M.ulcerans_Agy99 ALTRWRVRMEIEPGRRQTLAVVASVSAALVICLGSLLWSFISPSGQINDS
MLBr_01544|M.leprae_Br4923 ALTRWRVRMEVEPGRRQTLAVVASVSAALLGCLGALLWSFISPSGQLNES
. . .** : : : :: . : : * . .
MAB_3759c|M.abscessus_ATCC_199 PIVMGKDTGAVYVRIQ--DTLHPALNLASARLISGNNENPKPVKDSELAK
TH_3503|M.thermoresistible__bu TLLVDRTTNQLYVTLPGSDQLRPVYNLTSARLVLANNATPSAVKSEELDR
Mflv_0328|M.gilvum_PYR-GCK SILAERDTAALYVRLG--DQVHPVLNLASARLITGRPDNPAMVKSSELDE
Mvan_0412|M.vanbaalenii_PYR-1 AVLADRDTAALYVRLG--EQLHPVLNLTSARLIAGRPDNPAMVKSSELDQ
MSMEG_0616|M.smegmatis_MC2_155 AILADRSTSALYVRVG--EQLHPVLNLTSARLISGSPDNPTMVKTSEIDK
Rv3895c|M.tuberculosis_H37Rv AIIGDRDSGALYARID--GRLYPALNLTSARLATGTAGQPTWVKPAEIAK
Mb3925c|M.bovis_AF2122/97 AIIGDRDSGALYARID--GRLYPALNLTSARLATGTAGQPTWVKPAEIAK
MAV_5285|M.avium_104 TIIGDRDSGALYAKID--GRLYPALNLTSARLATGTANQPTWVKPAEIAK
MMAR_2664|M.marinum_M PIIADRDSGALYVRVG--DRLYPALNLASARLITGRASNPHLVRGSQIDS
MUL_3093|M.ulcerans_Agy99 PIIADRDSGALYVRVG--DRLYPALNLASARLITGRASNPHLVRGSQIDS
MLBr_01544|M.leprae_Br4923 PIIIDRDSGALYVRVG--DRLYPALNLASARLITGRPDNPHAVRSSQIAT
.:: : : :*. : : *. **:**** . * *: ::
MAB_3759c|M.abscessus_ATCC_199 ARRGPLVGIPGAPASIPGALTGDDTIWTVCDVAT---PPP--SSTVTTTV
TH_3503|M.thermoresistible__bu MPKGQPIGIPGAPYATP--LAAPQSTWTLCDTVT---RPESVSPTLRTSV
Mflv_0328|M.gilvum_PYR-GCK LPRGNMLGIPGAPGRMA-VNTTRDAYWTVCDAAA---GAV----TGVTVI
Mvan_0412|M.vanbaalenii_PYR-1 FPRGNLIGIPGAPERMV-ANTTRDAYWTVCDAAT---GST----AGVTVI
MSMEG_0616|M.smegmatis_MC2_155 FPRGNLLGIPGAPERMV-QNAATDAEWTVCDAVG---GAN----PGVTVI
Rv3895c|M.tuberculosis_H37Rv YPTGPLVGIPGAPAAMP-VNRGAVSAWAVCDTAG----RPRSADKPVVTS
Mb3925c|M.bovis_AF2122/97 YPTGPLVGIPGAPAAMP-VNRGAVSAWAVCDTAG----RPRSADKPVVTS
MAV_5285|M.avium_104 YPTGPLVGIPGAPAAMP-VHRGAISAWAVCDTAG----RPRSPEKPVVTS
MMAR_2664|M.marinum_M MPHGPLVGIPGAPSDFN-PASPATSSWLVCDTVAGPSTMPQSPHGVTVTV
MUL_3093|M.ulcerans_Agy99 MPHGPLVGIPGAPSDFN-PASPATSSWLVCDTVAGPSTMPQSPHGVTVTV
MLBr_01544|M.leprae_Br4923 LPHGPLVGIPGAPSELS-PETPQTSSWLVCDTVA-TSTGIGSSSGVTVTV
* :****** : * :**.. .
MAB_3759c|M.abscessus_ATCC_199 IAGKVTLENGNQEMPKDRYALVTVNSQ----MYLLYDGKRAAVDLTNPAV
TH_3503|M.thermoresistible__bu LVLPLATDTAVGPMNPNQGMLVTYQGK----PWLVTDRGRHSIDLADRAV
Mflv_0328|M.gilvum_PYR-GCK AGAPDDTGERATVLPDGHAVLAENNGR----TWLLWDGRRSAIDLADRAV
Mvan_0412|M.vanbaalenii_PYR-1 AGRPADGGERAAALPAGHAVLAENGGR----TWLLWDGKRSPIDLADRAV
MSMEG_0616|M.smegmatis_MC2_155 AGPLGADGERAAPLPPDHAVLVHSDAEPNPGDWLLWDGKRSPIDLADRAV
Rv3895c|M.tuberculosis_H37Rv IAGPITGGGRATHLRDDAGLLVTFDGS----TYVIWGGKRSQIDPTNRAV
Mb3925c|M.bovis_AF2122/97 IAGPITGGGRATHLRDDAGLLVTFDGS----TYVIWGGKRSQIDPTNRAV
MAV_5285|M.avium_104 IAGPLEGFDRAAPLRDDAGLLVTFEGN----TYVIWGGKRSQIDPVNRAV
MMAR_2664|M.marinum_M IDGTPDLTGHRRVLKGSDAVVLRYGGD----AWVIREGRRSRIDATDRSV
MUL_3093|M.ulcerans_Agy99 IDGTPDLTGHRRVLKGSDAVVLRYGGD----AWVIREGRRSRIDATDRSV
MLBr_01544|M.leprae_Br4923 IDGSPDLSGHRRVLTGSDAVVLHYGGD----AWVIRQGRRSRIDAMNRSV
: . : . ::: * :* : :*
MAB_3759c|M.abscessus_ATCC_199 TRALRLEG---VTPRPISMNVLNAIPEVPAIAPPPIPDAGAASPITTAGV
TH_3503|M.thermoresistible__bu TSAVGIPVT--ARATPISTGLFNALPNAGPWQVPDVPAAGAPNTVGLPEH
Mflv_0328|M.gilvum_PYR-GCK AGGVGIGVG-VAAPQPIATGLFNAIPEAPALITPVIPNAGLPSDLGLPEP
Mvan_0412|M.vanbaalenii_PYR-1 TGGLGIGVD-SAAPQPISVGLFNAIPEGPPLVTPAIPGAGSPSAAPLPEP
MSMEG_0616|M.smegmatis_MC2_155 TDALGLGGQ-ALAPRPIAAGLFNAVPAAPALTAPVIPDAGAAPQFELSLP
Rv3895c|M.tuberculosis_H37Rv TLSLGLDPG-VTSPIQISRALFDGLPATEPLRVPAVPEAGTP-STWVPGA
Mb3925c|M.bovis_AF2122/97 TLSLGLDPG-VTSPIQISRALFDGLPATEPLRVPAVPEAGTP-STWVPGA
MAV_5285|M.avium_104 TLSLGLDPG-VTLPVEISRALFDALPATEPLGVPPVPLAGTP-STWVSGS
MMAR_2664|M.marinum_M LLPLGLTPEQVTQARPMSHALYDALPVGPELVVPEVPDDGAA-ATFPGAP
MUL_3093|M.ulcerans_Agy99 LLPLGLTPEQVTQARPMSHALYDALPVGPELVVPEVPDDGAA-ATFPGAP
MLBr_01544|M.leprae_Br4923 LLPLGLTPEQVSQARPMSRALFDALPVGPDLVVPDVPNEGNP-ASFPGAP
: : . :: : :.:* * :* * .
MAB_3759c|M.abscessus_ATCC_199 RVGSVIKMSRAD--SAEYYVVLAGGVQRINEVTADLIRFSDSQGAQEIVT
TH_3503|M.thermoresistible__bu LVIGSVFKTVTD--SEQHYVVLPDGVARVNNTTAAALRARNSYGLVMPPT
Mflv_0328|M.gilvum_PYR-GCK FPVGSVVVSYDEDNTLRHYVVLTDGLQPISPVVAAILRNSNSWGLASPPR
Mvan_0412|M.vanbaalenii_PYR-1 LPIGAVVVAYDADNAIRHYVVLADGLQAVSPVVAAILRNSNSYGLAQPPR
MSMEG_0616|M.smegmatis_MC2_155 VPVGAVVVAYDADNTARYYAVLSDGLQPISPVLAAILRNTDSHGFAQPPR
Rv3895c|M.tuberculosis_H37Rv -RVGSVLQAQTAGGGSQFYVLLPDGVQKISSFVADLLRSANSYGAAAPRV
Mb3925c|M.bovis_AF2122/97 -RVGSVLQAQTAGGGSQFYVLLPDGVQKISSFVADLLRSANSYGAAAPRV
MAV_5285|M.avium_104 -QVGAVLQAQTASGGTQFYVLLPDGVQKVTSFVADLLRSANSYGSTAPRV
MMAR_2664|M.marinum_M GPVGTVIVTPQISGPQQYSLVLTDGVQTLPPLVAQILQNAGRPGNTKPVT
MUL_3093|M.ulcerans_Agy99 GPVGTVIVTPQISGPQQYSLVLTDGVQTLPPLVAQILQNAGRPGNTKPVT
MLBr_01544|M.leprae_Br4923 GPVGTVIVTPQISGPQQYSLVLADGVETVSPLVAQIMQNAGKPGNTKLIT
. : : .. :*..*: : * :: . *
MAB_3759c|M.abscessus_ATCC_199 VAPDVIAGHPSLNLLAVQTFPDRAGKIVDVPEKSVLCSSWKPGQEKTQEH
TH_3503|M.thermoresistible__bu IESSVVARIP--EHVFVSPLPDRPLDMLLREETPTLCWSWQ--REPGDQA
Mflv_0328|M.gilvum_PYR-GCK LDADLVARTPQAEVVDVDAYPAERVTLVDTAAEPVICAAWS--EHEGAQE
Mvan_0412|M.vanbaalenii_PYR-1 LDADVVARIPEAAGVDNAAYPSDRVTLVDVAADPVTCAQWA--KPEGAQD
MSMEG_0616|M.smegmatis_MC2_155 LGPDEVARTPMSRGLDTSAYPDNPVTLVEASAHPVTCAHWT--KPSDAAE
Rv3895c|M.tuberculosis_H37Rv VTPDVLVHTPQVTSLPVEYYPAGRLNFVDTAADPTTCVSWE--KASTDPQ
Mb3925c|M.bovis_AF2122/97 VTPDVLVHTPQVTSLPVEYYPAGRLNFVDTAADPTTCVSWE--KASTGPQ
MAV_5285|M.avium_104 VTPDVLVNIPEVTSLAVDYYPTKRLNFIDTAANPTTCVGWE--KGSTDPQ
MMAR_2664|M.marinum_M VQPSSLAKMPVVNRLDLSAYPDDPLNVMDIRDNPSTCWWWE--RTAGENR
MUL_3093|M.ulcerans_Agy99 VQPSSLAKMPVVNRLDLSAYPDDPLNVMDIRDNPSTCWWWE--RTAGENR
MLBr_01544|M.leprae_Br4923 VAPSVLVKMPVVNKLDLSVYPDTPLQVVDLRENPSTCWWWE--RTAGESR
: .. :. * : * .: . * * .
MAB_3759c|M.abscessus_ATCC_199 ASTKLLMGSSLPLKTDQVPVVLAQADKEGP----NLDTAYIPPARSAFVR
TH_3503|M.thermoresistible__bu PETTVIAGRRLPIAPSAMNRGIDQIGGD--------ATVYLAGGQYIRLQ
Mflv_0328|M.gilvum_PYR-GCK SSMELRSGAALPVADGVSTVALVSAGAPGG----PANQVALPQGTGYFVD
Mvan_0412|M.vanbaalenii_PYR-1 ASLTLRTGAVLPVADGARTVELVSSGTPGG----PADRVALPPGTGYFVD
MSMEG_0616|M.smegmatis_MC2_155 SSLSVLSGAVLPLAEGLHTVDLVGAGA-GG----AANRVALTPGTGYFVQ
Rv3895c|M.tuberculosis_H37Rv ARVAVYNGRGLPVPPSMDSRIVRLVRDDRAPASVVATQVLVLPGAANFVT
Mb3925c|M.bovis_AF2122/97 ARVAVYNGRGLPVPPSMDSRIVRLVRDDRAPASVVATQVLVLPGAANFVT
MAV_5285|M.avium_104 ARVVVYNGRGLPTPSYLDNRIVHLVRDDRDPASVVANQVLVLPGAANFVT
MMAR_2664|M.marinum_M SRVQVISGPNIPVAPHEMNKVVDLVKADMS--GREADQVYFGPNFANFVA
MUL_3093|M.ulcerans_Agy99 SRVQVISGPNIPVAPHEMNKVVDLAKADMS--GREAEQVYFGPNFANFVA
MLBr_01544|M.leprae_Br4923 SRIQVITGSTIPINSADVKKVVSLVKADTT--GREADQVYFGSNYANFVA
. : * :* : . . :
MAB_3759c|M.abscessus_ATCC_199 STGLGGDTGRAESLYLILDTGVRFGIGNLE------AAKALGLN-VEPVP
TH_3503|M.thermoresistible__bu SP----DPRYGESLYYIDPQGVRYGLPDED------TAGYLGLH-G-PAT
Mflv_0328|M.gilvum_PYR-GCK ---------NAGSLFWLSDTGVRYGIDTGADADGADTVAALGLT-TTPLP
Mvan_0412|M.vanbaalenii_PYR-1 ---------SAGSLFWISDTGVRYGIDTGS--DGVDTVAALGLT-TAPLP
MSMEG_0616|M.smegmatis_MC2_155 TVGAEPGSPTAGSMFWVSDTGVRYGIDTAE---DDKVVAALGLS-TSPLP
Rv3895c|M.tuberculosis_H37Rv STSGVITAESRESLFWVSGNGVRFGIANDE-----ATLRALGLDPGAAVQ
Mb3925c|M.bovis_AF2122/97 STSGVITAESRESLFWVSGNGVRFGIANDE-----ATLRALGLDPGAAVQ
MAV_5285|M.avium_104 STSGVVTSDSRESLFWVSDNGVRFGIANDE-----STLRALGLDPGSAVQ
MMAR_2664|M.marinum_M VTGNNPAAQTTESLWWLTEAGARFGVEDTK-----EAREALGLG-LTPSP
MUL_3093|M.ulcerans_Agy99 VTGNNPAAQTTESLWWLTEAGARFGVEDTK-----EAREALGLG-LTPSP
MLBr_01544|M.leprae_Br4923 VTGNNPAAQTTESLWWVTRTGARFGVEDTK-----DVRDALGLN-GTPNL
*:: : *.*:*: . *** .
MAB_3759c|M.abscessus_ATCC_199 APWPIVGLLPPGPRLSKEDALVVHDGMPPDKTGLAINPSTSATQAPS--
TH_3503|M.thermoresistible__bu APWQVVSLLVDGPVLSKAAALVEHDVLPGNPHPRKIADGAAAAPGPGGG
Mflv_0328|M.gilvum_PYR-GCK IPSSVLSLFAAGPTLSRGDALLAHDTLAPNPSPARVEALPGLENP----
Mvan_0412|M.vanbaalenii_PYR-1 IPSSVLSQFAVGPTLSRTDALLAHDSLAPNPAPARLETTSALEKP----
MSMEG_0616|M.smegmatis_MC2_155 VPWSVLSQFAAGPALSRGDALVAHDAVSTNPNSARMEASR---------
Rv3895c|M.tuberculosis_H37Rv APWPLLRTFAAGPALSRDAALLARDTVPTLGQVAIVTTTAKAGA-----
Mb3925c|M.bovis_AF2122/97 APWPLLRTFAAGPALSRDAALLARDTVPTLGQVAIVTTTAKAGA-----
MAV_5285|M.avium_104 APWPLLRTFAAGPALSREAALLARDTVPALGKVAVVTTSAKPGG-----
MMAR_2664|M.marinum_M APWVVLRLLPQGPTLSRADALVEHDTLPMDMSPAELVVPK---------
MUL_3093|M.ulcerans_Agy99 TPWVVLRLLPQGPTLSRADALVEHDTLPMDMSPAELVVPK---------
MLBr_01544|M.leprae_Br4923 APWVALRLLSQGPTLSRADALMEHDTLPMDMTPAELVVPK---------
* : : ** **: **: :* :. :