For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
AEESSGRRGSEYGLGLSTRTQVTGYQFLARRTAMALTRWRVRMEVEPGRRQTLAVVASVSAALLGCLGAL LWSFISPSGQLNESPIIIDRDSGALYVRVGDRLYPALNLASARLITGRPDNPHAVRSSQIATLPHGPLVG IPGAPSELSPETPQTSSWLVCDTVATSTGIGSSSGVTVTVIDGSPDLSGHRRVLTGSDAVVLHYGGDAWV IRQGRRSRIDAMNRSVLLPLGLTPEQVSQARPMSRALFDALPVGPDLVVPDVPNEGNPASFPGAPGPVGT VIVTPQISGPQQYSLVLADGVETVSPLVAQIMQNAGKPGNTKLITVAPSVLVKMPVVNKLDLSVYPDTPL QVVDLRENPSTCWWWERTAGESRSRIQVITGSTIPINSADVKKVVSLVKADTTGREADQVYFGSNYANFV AVTGNNPAAQTTESLWWVTRTGARFGVEDTKDVRDALGLNGTPNLAPWVALRLLSQGPTLSRADALMEHD TLPMDMTPAELVVPK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_01544 | - | - | 100% (506) | hypothetical protein MLBr_01544 |
| M. leprae Br4923 | MLBr_02536 | - | 4e-85 | 36.59% (511) | hypothetical protein MLBr_02536 |
| M. leprae Br4923 | MLBr_00054 | - | 2e-68 | 32.65% (490) | hypothetical protein MLBr_00054 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1811 | - | 0.0 | 82.61% (506) | hypothetical protein Mb1811 |
| M. gilvum PYR-GCK | Mflv_0328 | - | 4e-84 | 37.25% (494) | hypothetical protein Mflv_0328 |
| M. tuberculosis H37Rv | Rv1782 | - | 0.0 | 82.81% (506) | hypothetical protein Rv1782 |
| M. abscessus ATCC 19977 | MAB_3759c | - | 3e-72 | 34.91% (487) | hypothetical protein MAB_3759c |
| M. marinum M | MMAR_2664 | - | 0.0 | 80.67% (507) | hypothetical protein MMAR_2664 |
| M. avium 104 | MAV_2933 | - | 0.0 | 80.43% (506) | hypothetical protein MAV_2933 |
| M. smegmatis MC2 155 | MSMEG_0616 | - | 4e-82 | 35.73% (501) | hypothetical protein MSMEG_0616 |
| M. thermoresistible (build 8) | TH_3503 | - | 3e-63 | 32.11% (492) | PUTATIVE protein of unknown function DUF690 |
| M. ulcerans Agy99 | MUL_3093 | - | 0.0 | 80.08% (507) | hypothetical protein MUL_3093 |
| M. vanbaalenii PYR-1 | Mvan_0412 | - | 7e-86 | 37.78% (495) | hypothetical protein Mvan_0412 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0328|M.gilvum_PYR-GCK MSGAD--GDRRSFTSRTPTNENPDRVSFRRGFVTRHQVSGWRFMVRRMAS
Mvan_0412|M.vanbaalenii_PYR-1 MSAPE--EERRSFASRTPTNGNPDRVTYRRGFVTRHQVTGWRFVMRRIAS
MSMEG_0616|M.smegmatis_MC2_155 MTGPVNPDDRRSFSSRTPVNENPDGVQYRRGFVTRHQVSGWRFVMRRIAS
Mb1811|M.bovis_AF2122/97 ---------------MAEESRGQRGSGYGLGLSTRTQVTGYQFLARRTAM
Rv1782|M.tuberculosis_H37Rv ---------------MAEESRGQRGSGYGLGLSTRTQVTGYQFLARRTAM
MMAR_2664|M.marinum_M ---------------MAEQGRGQRGSGYGLGLSTRTQVTGYQFLARRTAM
MUL_3093|M.ulcerans_Agy99 ---------------MAEQGRGQRGSGYGLGLSTRTQVTGYQFLARRTAM
MAV_2933|M.avium_104 ---------------MAEESRGQRGSGYGLGLSTRTQVTGYQFLARRTAM
MLBr_01544|M.leprae_Br4923 ---------------MAEESSGRRGSEYGLGLSTRTQVTGYQFLARRTAM
MAB_3759c|M.abscessus_ATCC_199 ---------------------------MARQPTTRLQVSGYRFLVRRMEH
TH_3503|M.thermoresistible__bu --------------------------MAGFRLTTKVQVSGWRFLLRRVEH
*: **:*::*: **
Mflv_0328|M.gilvum_PYR-GCK GVALHDTRMLVDPLRTQSRSVLVGALILVTGLIGCFLFSLIRPAGDVGTD
Mvan_0412|M.vanbaalenii_PYR-1 GVALHDTRMLVDPLRTQSRSVLVGALILVTGLIGCFLFSLIRPSGAAGTD
MSMEG_0616|M.smegmatis_MC2_155 GVALHDTRMLVDPLRTQSRAVLTGALILVTGLVGCFIFSLFRPGGVPGNN
Mb1811|M.bovis_AF2122/97 ALTRWHVRMEIEPGRRQTLAVVASVSAALVICLGALLWSFISPSGQLNES
Rv1782|M.tuberculosis_H37Rv ALTRWRVRMEIEPGRRQTLAVVASVSAALVICLGALLWSFISPSGQLNES
MMAR_2664|M.marinum_M ALTRWRVRMEIEPGRRQTLAVVASVSAALVICLGSLLWSFISPSGQINDS
MUL_3093|M.ulcerans_Agy99 ALTRWRVRMEIEPGRRQTLAVVASVSAALVICLGSLLWSFISPSGQINDS
MAV_2933|M.avium_104 ALTRWRVRMEVEPGRRQNLAVVASVSAALVICLGALLWSFISPAGQVGDS
MLBr_01544|M.leprae_Br4923 ALTRWRVRMEVEPGRRQTLAVVASVSAALLGCLGALLWSFISPSGQLNES
MAB_3759c|M.abscessus_ATCC_199 ALVRRDVRMIHDPMRSQSSSLMVGIVLATVVVAGCAILAFFRPNMPLGDQ
TH_3503|M.thermoresistible__bu AIVRRDTRMFDDPLQFYSRAVQAGIVISVLICLGAVLLAYFKPLGKRGGD
.:. .** :* : . :: .. *. : : : * . .
Mflv_0328|M.gilvum_PYR-GCK SILAERDTAALYVRLG--DQVHPVLNLASARLITGRPDNPAMVKSSELDE
Mvan_0412|M.vanbaalenii_PYR-1 AVLADRDTAALYVRLG--EQLHPVLNLTSARLIAGRPDNPAMVKSSELDQ
MSMEG_0616|M.smegmatis_MC2_155 AILADRSTSALYVRVG--EQLHPVLNLTSARLISGSPDNPTMVKTSEIDK
Mb1811|M.bovis_AF2122/97 PIIADRDSGALYVRVG--DRLYPALNLASARLITGRPDNPHLVRSSQIAT
Rv1782|M.tuberculosis_H37Rv PIIADRDSGALYVRVG--DRLYPALNLASARLITGRPDNPHLVRSSQIAT
MMAR_2664|M.marinum_M PIIADRDSGALYVRVG--DRLYPALNLASARLITGRASNPHLVRGSQIDS
MUL_3093|M.ulcerans_Agy99 PIIADRDSGALYVRVG--DRLYPALNLASARLITGRASNPHLVRGSQIDS
MAV_2933|M.avium_104 PIIADRDSGALYVRVG--DRLYPALNLASARLITGRPDNPHLVKSNQIAS
MLBr_01544|M.leprae_Br4923 PIIIDRDSGALYVRVG--DRLYPALNLASARLITGRPDNPHAVRSSQIAT
MAB_3759c|M.abscessus_ATCC_199 PIVMGKDTGAVYVRIQ--DTLHPALNLASARLISGNNENPKPVKDSELAK
TH_3503|M.thermoresistible__bu TLLVDRTTNQLYVTLPGSDQLRPVYNLTSARLVLANNATPSAVKSEELDR
.:: : : :** : : : *. **:****: . .* *: .::
Mflv_0328|M.gilvum_PYR-GCK LPRGNMLGIPGAPGRMA-VNTTRDAYWTVCDAAAGAVTG--------VTV
Mvan_0412|M.vanbaalenii_PYR-1 FPRGNLIGIPGAPERMV-ANTTRDAYWTVCDAATGSTAG--------VTV
MSMEG_0616|M.smegmatis_MC2_155 FPRGNLLGIPGAPERMV-QNAATDAEWTVCDAVGGANPG--------VTV
Mb1811|M.bovis_AF2122/97 MPRGPLVGIPGAPSSFS-PKSPPASSWLVCDTVATSSSIG-SLQGVTVTV
Rv1782|M.tuberculosis_H37Rv MPRGPLVGIPGAPSSFS-PKSPPASSWLVCDTVATSSSIG-SLQGVTVTV
MMAR_2664|M.marinum_M MPHGPLVGIPGAPSDFN-PASPATSSWLVCDTVAGPSTMPQSPHGVTVTV
MUL_3093|M.ulcerans_Agy99 MPHGPLVGIPGAPSDFN-PASPATSSWLVCDTVAGPSTMPQSPHGVTVTV
MAV_2933|M.avium_104 LPRGPMVGIPGAPSNFH-PTGPSTSSWLVCDTVSNSTGAG-APSGVTVTV
MLBr_01544|M.leprae_Br4923 LPHGPLVGIPGAPSELS-PETPQTSSWLVCDTVATSTGIG-SSSGVTVTV
MAB_3759c|M.abscessus_ATCC_199 ARRGPLVGIPGAPASIPGALTGDDTIWTVCDVATPPP-----SSTVTTTV
TH_3503|M.thermoresistible__bu MPKGQPIGIPGAPYATP--LAAPQSTWTLCDTVTRPESV---SPTLRTSV
:* :****** : * :**.. . .:*
Mflv_0328|M.gilvum_PYR-GCK IAGAPDDTGERATVLPDGHAVLAENNGR----TWLLWDGRRSAIDLADRA
Mvan_0412|M.vanbaalenii_PYR-1 IAGRPADGGERAAALPAGHAVLAENGGR----TWLLWDGKRSPIDLADRA
MSMEG_0616|M.smegmatis_MC2_155 IAGPLGADGERAAPLPPDHAVLVHSDAEPNPGDWLLWDGKRSPIDLADRA
Mb1811|M.bovis_AF2122/97 IDGTPDLTGHR-QILSGSDAVVLRYGGD----AWVIREGRRSRIEPTNRA
Rv1782|M.tuberculosis_H37Rv IDGTPDLTGHR-QILSGSDAVVLRYGGD----AWVIREGRRSRIEPTNRA
MMAR_2664|M.marinum_M IDGTPDLTGHR-RVLKGSDAVVLRYGGD----AWVIREGRRSRIDATDRS
MUL_3093|M.ulcerans_Agy99 IDGTPDLTGHR-RVLKGSDAVVLRYGGD----AWVIREGRRSRIDATDRS
MAV_2933|M.avium_104 IDGAPDLSNHR-KVLTGSDAVVLNYGGD----AWVIRDGRRSRIDATNRS
MLBr_01544|M.leprae_Br4923 IDGSPDLSGHR-RVLTGSDAVVLHYGGD----AWVIRQGRRSRIDAMNRS
MAB_3759c|M.abscessus_ATCC_199 IAGKVTLENGN-QEMPKDRYALVTVNSQ----MYLLYDGKRAAVDLTNPA
TH_3503|M.thermoresistible__bu LVLPLATDTAV-GPMNPNQGMLVTYQGK----PWLVTDRGRHSIDLADRA
: : . : . ::: : * :: : :
Mflv_0328|M.gilvum_PYR-GCK VAGGVGIG-VGVAAPQPIATGLFNAIPEAPALITPVIPNAGLPSDLGLPE
Mvan_0412|M.vanbaalenii_PYR-1 VTGGLGIG-VDSAAPQPISVGLFNAIPEGPPLVTPAIPGAGSPSAAPLPE
MSMEG_0616|M.smegmatis_MC2_155 VTDALGLG-GQALAPRPIAAGLFNAVPAAPALTAPVIPDAGAAPQFELSL
Mb1811|M.bovis_AF2122/97 VLLPLGLTPEQVSQARPMSRALFDALPVGPELLVPEVPNAGGPATFPG-A
Rv1782|M.tuberculosis_H37Rv VLLPLGLTPEQVSQARPMSRALFDALPVGPELLVPEVPNAGGPATFPG-A
MMAR_2664|M.marinum_M VLLPLGLTPEQVTQARPMSHALYDALPVGPELVVPEVPDDGAAATFPG-A
MUL_3093|M.ulcerans_Agy99 VLLPLGLTPEQVTQARPMSHALYDALPVGPELVVPEVPDDGAAATFPG-A
MAV_2933|M.avium_104 VLLPLGLTPEQVSMAKPMSRALYDALPVGPELTVPQIQNAGGAASFPG-A
MLBr_01544|M.leprae_Br4923 VLLPLGLTPEQVSQARPMSRALFDALPVGPDLVVPDVPNEGNPASFPG-A
MAB_3759c|M.abscessus_ATCC_199 VTR--ALRLEG-VTPRPISMNVLNAIPEVPAIAPPPIPDAGAASPITTAG
TH_3503|M.thermoresistible__bu VTS--AVGIPVTARATPISTGLFNALPNAGPWQVPDVPAAGAPNTVGLPE
* .: . *:: : :*:* * : * .
Mflv_0328|M.gilvum_PYR-GCK PFPVGSVVVSYDEDNTLRHYVVLTDGLQPISPVVAAILRNSNSWGLASPP
Mvan_0412|M.vanbaalenii_PYR-1 PLPIGAVVVAYDADNAIRHYVVLADGLQAVSPVVAAILRNSNSYGLAQPP
MSMEG_0616|M.smegmatis_MC2_155 PVPVGAVVVAYDADNTARYYAVLSDGLQPISPVLAAILRNTDSHGFAQPP
Mb1811|M.bovis_AF2122/97 PGPIGTVIVTPQISGPQQYSLVLGDGVQTLPPLVAQILQNAGSAGNTKPL
Rv1782|M.tuberculosis_H37Rv PGPIGTVIVTPQISGPQQYSLVLGDGVQTLPPLVAQILQNAGSAGNTKPL
MMAR_2664|M.marinum_M PGPVGTVIVTPQISGPQQYSLVLTDGVQTLPPLVAQILQNAGRPGNTKPV
MUL_3093|M.ulcerans_Agy99 PGPVGTVIVTPQISGPQQYSLVLTDGVQTLPPLVAQILQNAGRPGNTKPV
MAV_2933|M.avium_104 PGPIGTVLVTPQISGPQQYSLVLADGVQTLPPLVAQILQNAG-PGNTKPV
MLBr_01544|M.leprae_Br4923 PGPVGTVIVTPQISGPQQYSLVLADGVETVSPLVAQIMQNAGKPGNTKLI
MAB_3759c|M.abscessus_ATCC_199 VRVGSVIKMS--RADSAEYYVVLAGGVQRINEVTADLIRFSDSQGAQEIV
TH_3503|M.thermoresistible__bu HLVIGSVFKT--VTDSEQHYVVLPDGVARVNNTTAAALRARNSYGLVMPP
. : : .. .: ** .*: : * :: . *
Mflv_0328|M.gilvum_PYR-GCK RLDADLVARTPQAEVVDVDAYPAERVTLVDTAAEPVICAAWSE--HEGAQ
Mvan_0412|M.vanbaalenii_PYR-1 RLDADVVARIPEAAGVDNAAYPSDRVTLVDVAADPVTCAQWAK--PEGAQ
MSMEG_0616|M.smegmatis_MC2_155 RLGPDEVARTPMSRGLDTSAYPDNPVTLVEASAHPVTCAHWTK--PSDAA
Mb1811|M.bovis_AF2122/97 TVEPSTLAKMPVVNRLDLSAYPDNPLEVVDIREHPSTCWWWER--TAGEN
Rv1782|M.tuberculosis_H37Rv TVEPSTLAKMPVVNRLDLSAYPDNPLEVVDIREHPSTCWWWER--TAGEN
MMAR_2664|M.marinum_M TVQPSSLAKMPVVNRLDLSAYPDDPLNVMDIRDNPSTCWWWER--TAGEN
MUL_3093|M.ulcerans_Agy99 TVQPSSLAKMPVVNRLDLSAYPDDPLNVMDIRDNPSTCWWWER--TAGEN
MAV_2933|M.avium_104 TVEPSALAKMPVVNKLDLSSYPDAPLNVMDIRENPATCWWWQK--TSGEN
MLBr_01544|M.leprae_Br4923 TVAPSVLVKMPVVNKLDLSVYPDTPLQVVDLRENPSTCWWWER--TAGES
MAB_3759c|M.abscessus_ATCC_199 TVAPDVIAGHPSLNLLAVQTFPDRAGKIVDVPEKSVLCSSWKPGQEKTQE
TH_3503|M.thermoresistible__bu TIESSVVARIP--EHVFVSPLPDRPLDMLLREETPTLCWSWQ--REPGDQ
: .. :. * : * :: . * *
Mflv_0328|M.gilvum_PYR-GCK ESSMELRSGAALPVADGVS--TVALVSAGAPGGPANQVALPQGTGYFVD-
Mvan_0412|M.vanbaalenii_PYR-1 DASLTLRTGAVLPVADGAR--TVELVSSGTPGGPADRVALPPGTGYFVD-
MSMEG_0616|M.smegmatis_MC2_155 ESSLSVLSGAVLPLAEGLH--TVDLVGAGA-GGAANRVALTPGTGYFVQT
Mb1811|M.bovis_AF2122/97 RARVRVVSGPTIPVAATEMNKVVSLVKADTSGRQADQVYFGPDHANFVAV
Rv1782|M.tuberculosis_H37Rv RARVRVVSGPTIPVAATEMNKVVSLVKADTSGRQADQVYFGPDHANFVAV
MMAR_2664|M.marinum_M RSRVQVISGPNIPVAPHEMNKVVDLVKADMSGREADQVYFGPNFANFVAV
MUL_3093|M.ulcerans_Agy99 RSRVQVISGPNIPVAPHEMNKVVDLAKADMSGREAEQVYFGPNFANFVAV
MAV_2933|M.avium_104 RARVQVVSGATIPVAQKDVNKVVSLVKADTTGREADQVFFGPDYANFVAV
MLBr_01544|M.leprae_Br4923 RSRIQVITGSTIPINSADVKKVVSLVKADTTGREADQVYFGSNYANFVAV
MAB_3759c|M.abscessus_ATCC_199 HASTKLLMGSSLPLKTDQVP--VVLAQADKEGPNLDTAYIPPARSAFVRS
TH_3503|M.thermoresistible__bu APETTVIAGRRLPIAPSAMN--RGIDQIGGD----ATVYLAGGQYIRLQS
. : * :*: : . . : :
Mflv_0328|M.gilvum_PYR-GCK --------NAGSLFWLSDTGVRYGIDTGADADGADTVAALGLTTTPLPIP
Mvan_0412|M.vanbaalenii_PYR-1 --------SAGSLFWISDTGVRYGIDTGS--DGVDTVAALGLTTAPLPIP
MSMEG_0616|M.smegmatis_MC2_155 VGAEPGSPTAGSMFWVSDTGVRYGIDTAE---DDKVVAALGLSTSPLPVP
Mb1811|M.bovis_AF2122/97 TGNNPGAQTSESLWWVTDAGARFGVEDSK-----EARDALGLTLTPSLAP
Rv1782|M.tuberculosis_H37Rv TGNNPGAQTSESLWWVTDAGARFGVEDSK-----EARDALGLTLTPSLAP
MMAR_2664|M.marinum_M TGNNPAAQTTESLWWLTEAGARFGVEDTK-----EAREALGLGLTPSPAP
MUL_3093|M.ulcerans_Agy99 TGNNPAAQTTESLWWLTEAGARFGVEDTK-----EAREALGLGLTPSPTP
MAV_2933|M.avium_104 TGNDPGAKTTESLWWLTDAGARFGVDDTR-----DVREALGLKTKPSVAP
MLBr_01544|M.leprae_Br4923 TGNNPAAQTTESLWWVTRTGARFGVEDTK-----DVRDALGLNGTPNLAP
MAB_3759c|M.abscessus_ATCC_199 TGLGGDTGRAESLYLILDTGVRFGIGNLE------AAKALGLNVEPVPAP
TH_3503|M.thermoresistible__bu P----DPRYGESLYYIDPQGVRYGLPDED------TAGYLGLHG-PATAP
*:: : *.*:*: . *** * *
Mflv_0328|M.gilvum_PYR-GCK SSVLSLFAAGPTLSRGDALLAHDTLAPNPSPARVEALPGLENP----
Mvan_0412|M.vanbaalenii_PYR-1 SSVLSQFAVGPTLSRTDALLAHDSLAPNPAPARLETTSALEKP----
MSMEG_0616|M.smegmatis_MC2_155 WSVLSQFAAGPALSRGDALVAHDAVSTNPNSARMEASR---------
Mb1811|M.bovis_AF2122/97 WVALRLLPQGPTLSRADALVEHDTLPMDMTPAELVVPK---------
Rv1782|M.tuberculosis_H37Rv WVALRLLPQGPTLSRADALVEHDTLPMDMTPAELVVPK---------
MMAR_2664|M.marinum_M WVVLRLLPQGPTLSRADALVEHDTLPMDMSPAELVVPK---------
MUL_3093|M.ulcerans_Agy99 WVVLRLLPQGPTLSRADALVEHDTLPMDMSPAELVVPK---------
MAV_2933|M.avium_104 WVALRLLPQGPTLSRADALVQHDTLPMDMSPAELAVPK---------
MLBr_01544|M.leprae_Br4923 WVALRLLSQGPTLSRADALMEHDTLPMDMTPAELVVPK---------
MAB_3759c|M.abscessus_ATCC_199 WPIVGLLPPGPRLSKEDALVVHDGMPPDKTGLAINPSTSATQAPS--
TH_3503|M.thermoresistible__bu WQVVSLLVDGPVLSKAAALVEHDVLPGNPHPRKIADGAAAAPGPGGG
: : ** **: **: ** :. : :