For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
SKKAFPINRVNIDPPKPVRVAPNPPIALPEREPRNIWVMIGVPALIVALIGTIVMLYVSGVRSLATGFFP LMGIGAFSMLAFSGRFGRARKITWGELEKGRRRYLRDLDTNRDEIQTAVCAQREWQNAVHSDPPGLGAII GGPRMWERGRGDVDFLEVRVGTGVQHAPDSVLSVTWPDISSDEELEPVTGQALRDFILEQRKIRDIAKVV NLRSAPGFSFVSEDLDRVRSLMRSVLCSLAVFHNPRDVKLMVVTRNREVWAWMVWLPHNLHDELFDACGW RRLIFATPEELEAALGAELHMKGKRGAWTPPTVASPTAMGSALETGQVGVDLGPHLVIVDDNTGSPDAWE SVVGQVGKAGLTVLRIASRVGTGVGFAEDQVFEMAQRHGAATAVKAGRDGADADDDQRPAPLLRARGTFF AHADQLSIHRAYRYARAMARWSPTSRSEVTDSTSGAAELLRSLGISDPRELDVDRLWAERRGRGDDRWCE IPVGAKPNGELQNIILRAKDFGGFGFHSVVIGTSGSGKSELFLSLVYGIALTHSPETFNVIFVDMKFESA AQDILGIPHVVAALSNLGKDERHLAERMRRVIDGEIKQRYELFKSVGARDANDYEEIRLAGRDLPPVPVL LVIVDEYLELFANHKKWIDLIIHIGQEGRGANVFFMLGGQRLDLSSLQKVKSNIAFRIALRAESGDDSRE VIGSDAAYHLPSKENGFALLKVGPRDLEPFRCFYLSAPFVVPKKKEVARTIDMTLTQPRLYDWQYQPLDA ADAEALATAAAADAEPDEFLYYDDGFKKKKIVDVLRESLYNVPHRSPRRPWLAPLEDPEPVDRLVAAYRG KPWHVDYGQNPGLMFPVGVMDIPEESQQVVHAVDALRSNIIVVGAKQRGKTTTLMALMCSAATMYTPERV TFFCIGGATMAQIGSLPHVTDIVSPKDAEGIERILSTMDALIDAREEAFRRAKIDMDGFRERRFGIGGDG VGGTDPTDAFGDVFVVLDDYDDLYAKDTLLGDRIISLSSRGPEYGVHLMCSAGGWIHGQRQSLLQNVTAR IQLRLADPGESQMGHLSIESREAARRTLNRPGFGLTESLHELRIGVPALADPGTGELVGITDVGARIADV AGVTKHASLQRLPQRVELSAIVEHEAVHQGGDDLSIAFAIGERHELGPVPIKLRESPGLMILGRQGCGKT TALVAIGEAVMNRFSPQQAQLTLIDPKTAPHGLRDLHAPGYVRAYAYDQDEIDEVITELAQQILLPRLPP KGLSQEELRALKPWEGPRHFVLIDDVQDLRPAQSYPQKPPVGAALWKLMERARQVGLHVFSTRNSANWAT MPMDPWVKSQTSAKVAQLYMDNDPQNRINRSVRAQTLPPGRGLLVGADGDVEGILVGYPSVPGEQ*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv3894c | - | - | 100% (1396) | POSSIBLE CONSERVED MEMBRANE PROTEIN |
M. tuberculosis H37Rv | Rv3447c | - | e-133 | 28.16% (1392) | hypothetical protein Rv3447c |
M. tuberculosis H37Rv | Rv0284 | - | e-119 | 27.63% (1408) | hypothetical protein Rv0284 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3924c | - | 0.0 | 99.87% (771) | hypothetical protein Mb3924c |
M. gilvum PYR-GCK | Mflv_0327 | - | 1e-110 | 27.49% (1426) | cell divisionFtsK/SpoIIIE |
M. leprae Br4923 | MLBr_01543 | - | 1e-160 | 30.80% (1406) | putative SpoIIIE-family membrane protein |
M. abscessus ATCC 19977 | MAB_3756c | - | 1e-146 | 29.34% (1404) | putative FtsK/SpoIIIE family protein |
M. marinum M | MMAR_2665 | - | 1e-154 | 29.97% (1448) | FtsK/SpoIIIE family protein |
M. avium 104 | MAV_2932 | - | 1e-161 | 30.46% (1428) | ftsk/SpoIIIE family protein |
M. smegmatis MC2 155 | MSMEG_0617 | - | 1e-114 | 26.19% (1424) | ftsk/SpoIIIE family protein |
M. thermoresistible (build 8) | TH_2597 | - | 1e-131 | 29.57% (1380) | PUTATIVE cell divisionFtsK/SpoIIIE |
M. ulcerans Agy99 | MUL_3092 | - | 1e-152 | 29.95% (1456) | FtsK/SpoIIIE family protein |
M. vanbaalenii PYR-1 | Mvan_0413 | - | 1e-106 | 26.73% (1429) | cell divisionFtsK/SpoIIIE |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_2665|M.marinum_M -MKRGFARPTPEKAPVIKPENIVLPTPLSIPPPEGKPWWLIVVGVVVVGL MUL_3092|M.ulcerans_Agy99 -MKRGFARPTPEKAPVIKPENIVLPTPLSIPPPEGKPWWLIVVGVVVVGL MAV_2932|M.avium_104 ---------------MIKPENIVLPTPLSIPPPEGKPWWLVVVGVLVVGL MLBr_01543|M.leprae_Br4923 -----------------------------------------MIGVVVIGL Mflv_0327|M.gilvum_PYR-GCK MSRLIFEHRKRLPAPVARKGTITIEPPPELPRVVPPSLLRRALPYLIVIL Mvan_0413|M.vanbaalenii_PYR-1 MSRLIFEHRKRVPAPVVPKGTITIEPPPELPRVIPPSLLRRALPYLIVIL MSMEG_0617|M.smegmatis_MC2_155 MSRLIFEHQRRLTPPTTRKGTITIEPPPQLPRVVPPSLLRRVLPFLIVIL MAB_3756c|M.abscessus_ATCC_199 ----------------MPGGEVNVQPPPEIPRPVPSPIIAKIMPLVMVVA TH_2597|M.thermoresistible__bu -----------------------------VPRELPANPVARLLPLVMVVA Rv3894c|M.tuberculosis_H37Rv -MSKKAFPINRVNIDPPKPVRVAPNPPIALPEREPRNIWVMIGVPALIVA Mb3924c|M.bovis_AF2122/97 -MSKKAFPINRVNIDPPKPVRVAPNPPIALPEREPRNIWVMIGVPALIVA :: MMAR_2665|M.marinum_M LGGMVAMVFASGSH----VFGGVGSIFPIFMMVGIMMMMFRSVGAGGQQQ MUL_3092|M.ulcerans_Agy99 LGGMVAMVFASGSH----VFGGVGSIFPIFMMVGIMMMMFRSVGAGGQQQ MAV_2932|M.avium_104 LIGMVGMTFASGSH----VFGGAGAIFPIFMIGGVAMMMFGGR-FGGQQQ MLBr_01543|M.leprae_Br4923 VGGMVAMTFASGSR----VFGGAGSIFPLFMIGGVAMMMFSGR-MGGQQQ Mflv_0327|M.gilvum_PYR-GCK IVGMIVALVATG--------LRLISPTTLFFPFVLLLAATALYR-GTDNK Mvan_0413|M.vanbaalenii_PYR-1 IVGMIVALVATG--------LRMISPTMLFFPFVLLLAATALYR-GTDNK MSMEG_0617|M.smegmatis_MC2_155 IVGMIVALFATG--------MRLISPTMLFFPFVLLLAATALYR-GGDNK MAB_3756c|M.abscessus_ATCC_199 MVGMIAFFVTSGSFGGGAGGGMMRSPMFMLFPIMMMVSMVSMVSNSGGKG TH_2597|M.thermoresistible__bu MAGMLVLYFTS-------GNSAMRTPVFSFFPVLMVASAVGTLAYGARGT Rv3894c|M.tuberculosis_H37Rv LIGTIVMLYVSGVR-------SLATGFFPLMGIGAFSMLAFSGRFGRARK Mb3924c|M.bovis_AF2122/97 LIGTIVMLYVSGVR-------SLATGFFPLMGIGAFSMLAFSGRFGRARK : * : .: : :: . MMAR_2665|M.marinum_M MSRPKLDAMRAQFMLMLDMLRETAQESADSMDSNYRWFHPAPSTLAAAVG MUL_3092|M.ulcerans_Agy99 MSRPKLDAMRAQFMLMLDMLRETAQESADSMDSNYRWFHPAPSTLAAAVG MAV_2932|M.avium_104 MSRPKLDSMRAQFMLMLDMLRETAHESADSMDANYRWFHPAPTTLAAAVG MLBr_01543|M.leprae_Br4923 MSRPKLDAMRAQFMLMLDMLREAANESADSMDANYRWFHPAPTTLAAAVG Mflv_0327|M.gilvum_PYR-GCK MRTEEVDAERADYLRYLSVVRDNVRAHADEQRTALQWSHPEPAALNGIPG Mvan_0413|M.vanbaalenii_PYR-1 MRTEEVDAERADYLRYLSVVRDNVRAYADQQRAALQWSHPEPAALVSIPG MSMEG_0617|M.smegmatis_MC2_155 MRTEEVDAERADYLRYLSVVRDNVRAHAAEQRAALEWSHPEPEVLATIPG MAB_3756c|M.abscessus_ATCC_199 AKTSEINEDRKDYLRYLEVVRKNVTDTGAAQRKALLWNNPDPSALWTLAG TH_2597|M.thermoresistible__bu HRTAELNADRRQYLRHLDELDRQAAAAATAQQRSLHRRHPRPDALWTLAG Rv3894c|M.tuberculosis_H37Rv ITWGELEKGRRRYLRDLDTNRDEIQTAVCAQREWQNAVHSDPPGLGAIIG Mb3924c|M.bovis_AF2122/97 ITWGELEKGRRRYLRDLDTNRDEIQTAVCAQREWQNAVHSDPPGLGAIIG ::: * :: *. :. * * * MMAR_2665|M.marinum_M SPRMWERKPDGKDLNFGVVRVGVGMTRPEVTWGEPQNMPTDIELEPVTGK MUL_3092|M.ulcerans_Agy99 SPRMWERKPDGKDLNFGVVRVGVGMTRPEVTWGEPQNMPTDIELEPVTGK MAV_2932|M.avium_104 SPRMWERKPDGKDLNFGVVRVGVGMTRPEVTWGEPQNMPTDIELEPVTGK MLBr_01543|M.leprae_Br4923 SSRMWERKPDGKDLNFCVVRVGVGMTRPEVTWGEPQNMPTDIELEPVTGK Mflv_0327|M.gilvum_PYR-GCK TRRQWERDP--HDPDFLVLRAGLHDQPLDVTLRVK-DTADEIDLEPVSHT Mvan_0413|M.vanbaalenii_PYR-1 TRRQWERDP--HDPDFLVLRAGLHDQPLATALRVK-DTADEIDLEPVSHS MSMEG_0617|M.smegmatis_MC2_155 TRRQWERDP--RDRDFLVLRAGRHDVPLDAALKVK-DTADEIDLEPVAHS MAB_3756c|M.abscessus_ATCC_199 GRRMWERRP--GDSDYCHVRVGTGDQRLAAQLVAP-EIGPVEELEPVASV TH_2597|M.thermoresistible__bu GPRMWERAP--TDPDFGRIRVGVAAQPLTPGLIPP-DLPPAEEADPVTVS Rv3894c|M.tuberculosis_H37Rv GPRMWERGRGDVDFLEVRVGTGVQHAPDSVLSVTWPDISSDEELEPVTGQ Mb3924c|M.bovis_AF2122/97 GPRMWERGRGDVDFLEVRVGTGVQHAPDSVLSVTWPDISSDEELEPVTGQ * *** * : .* : : :**: MMAR_2665|M.marinum_M ALQEFGRYQSVVYNLPKMISLLVEP-WYALVGEREQALGLMRAIICQLTF MUL_3092|M.ulcerans_Agy99 ALQEFGRYQSVVYNLPKMISLLVEP-WYALVGEREQALGLMRAIICQLTF MAV_2932|M.avium_104 ALQEFGRYQSVVYNLPKMISLLVEP-WYSLAGDREQVLGLMRAIICQLTF MLBr_01543|M.leprae_Br4923 ALQEFGRYQSIVYNLPKMVSLLVEP-WYALIGDREQTLGLMRSIICQLTF Mflv_0327|M.gilvum_PYR-GCK TLRGLLDAQRTLYDVPAGIALTRVS-RITVLGDDAEVTGALRAWVAQAMT Mvan_0413|M.vanbaalenii_PYR-1 TLRSLLDTQRTIHDAPAGVDLTKVA-RITVIGDRAEVAGALRAWIAQAVT MSMEG_0617|M.smegmatis_MC2_155 ALRGLLDVQRTVRDAPTGLDVAKLA-RITVIGEADEARAAIRAWIAQAVT MAB_3756c|M.abscessus_ATCC_199 ALRRFVRTHSLVPELPIALNLRGFA-AVTIDGSPEVARGMLRAMICQLAM TH_2597|M.thermoresistible__bu AVQRLLRVRATVPDLPDTVAVFDHS-AITVTG--DDAHGLARAMICQLAV Rv3894c|M.tuberculosis_H37Rv ALRDFILEQRKIRDIAKVVNLRSAPGFSFVSEDLDRVRSLMRSVLCSLAV Mb3924c|M.bovis_AF2122/97 ALRDFILEQRKIRDIAKVVNLRSAPGFSFVSEDLDRVRSLMRSVLCSLAV ::: : : : : . : : . : . . *: :.. MMAR_2665|M.marinum_M SHGPDHVQFIVVSS--DLAEWEWVKWLPHFGDSRRYDAAGNARMVYSSVR MUL_3092|M.ulcerans_Agy99 SHGPDHVQFIVVSS--DLAEWEWVKWLPHFGDSRRYDAAGNARMVYSSVR MAV_2932|M.avium_104 SHGPDHVRMIVVSS--DLDEWDWVKWLPHFGDPRRQDAAGNARMVYSSVR MLBr_01543|M.leprae_Br4923 SHGPDHVQMVVVSS--DLEQWDWVKWLPHFGDPRRQDAAGNARMVYSSVR Mflv_0327|M.gilvum_PYR-GCK WHDPSVLGIAFAGEALESEAWSWLKWLPHVDVPGRIDGVGPARYLAGDAS Mvan_0413|M.vanbaalenii_PYR-1 WHDPSVLGVAFAGTRLESDAWSWLKWLPHTDVPGQNDGVGPARYLATEPA MSMEG_0617|M.smegmatis_MC2_155 WHDPTMLGVALAAPDLESGDWSWLKWLPHVDVPNEADGVGPARYLTTSTA MAB_3756c|M.abscessus_ATCC_199 FHGPDQFLVAAVVNRHAAPHWDWLKWLPHSQHPSAFDGVGTSRLVYHSLG TH_2597|M.thermoresistible__bu LHGPDVLRIATVTTGDDG-VWDWLKWLPHHRHP-----WCTGHLRHRDLT Rv3894c|M.tuberculosis_H37Rv FHNPRDVKLMVVTR--NREVWAWMVWLPHNLHDELFDACGWRRLIFATPE Mb3924c|M.bovis_AF2122/97 FHNPRDVKLMVVTR--NPEVWAWMVWLPHNLHDELFDACGWRRLIFATPE *.* . . . * *: **** : MMAR_2665|M.marinum_M EFAAEQGELFAGRGSFTPRHASSSAQTPTP---------------HTVII MUL_3092|M.ulcerans_Agy99 EFAAEQGELFAGRGSFTPRHASSSAQTPTP---------------HTVII MAV_2932|M.avium_104 EFAAEQAELFAGRGSFTPRHASSSAQTPTP---------------HTVII MLBr_01543|M.leprae_Br4923 EFATEQAELFAGRGSFTPRHASSSAQTPTP---------------HHLIV Mflv_0327|M.gilvum_PYR-GCK DLRTLLAPALADRSGFTGD-----ATGTTK---------------HLLIV Mvan_0413|M.vanbaalenii_PYR-1 ALHALLAPALAERAPFTGD-----GPTDAK---------------HLLVV MSMEG_0617|M.smegmatis_MC2_155 ELRERLAPALADRPLFPAE-----SGAALK---------------HLLVV MAB_3756c|M.abscessus_ATCC_199 EVEESLASLITERERFSRTAQP--SPDRPQ---------------ILIVV TH_2597|M.thermoresistible__bu EIDR--------------------AADRAR---------------WLVIR Rv3894c|M.tuberculosis_H37Rv ELEAALGAELHMKGKRGAWTPPTVASPTAMGSALETGQVGVDLGPHLVIV Mb3924c|M.bovis_AF2122/97 ELEAALGAELHMKGKRGAWTPPTVASPTAMGSALETGQVGVDLGPHLVIV . . :: MMAR_2665|M.marinum_M CDVDDP--QWEYVISAEGVDGVTFFDLTGSP------------MWTNVPE MUL_3092|M.ulcerans_Agy99 CDVDDP--QWEYVISAEGVDGVTFFDLTGSP------------MWTNVPE MAV_2932|M.avium_104 ADAVDP--QWEYVISAEGVDGVTFFDLTGSS------------MWSSVPE MLBr_01543|M.leprae_Br4923 ADVVDP--EWEYVISVEGIDGVTFFDLTGSS------------MWTVVPK Mflv_0327|M.gilvum_PYR-GCK LDDPDA--DPSEFIGS-GLAGVTVIHRS-----------------ATEPD Mvan_0413|M.vanbaalenii_PYR-1 LDDPDA--DPGQFIGR-GLAGVTVIHRT-----------------DREPD MSMEG_0617|M.smegmatis_MC2_155 LDDPDA--DPDDIARKPGLTGVTVIHRT-----------------TELPN MAB_3756c|M.abscessus_ATCC_199 DSGTLI--GSERLIVDHGIDSVTLVEIG-----------------TRVDP TH_2597|M.thermoresistible__bu DG---------HRGEDAAPPGVTVLTVA-----------------SAADS Rv3894c|M.tuberculosis_H37Rv DDNTGSPDAWESVVGQVGKAGLTVLRIASRVGTGVGFAEDQVFEMAQRHG Mb3924c|M.bovis_AF2122/97 DDNTGSPDAWESVVGQVGKAGLTVLRIASRVGTGVGFAEDQVFEMAQRHG . . .:*.. MMAR_2665|M.marinum_M RKLEFDKTGVIEALPRDRDTWMVIDDNAWFFALTDHVSIAEAEEFGQKLA MUL_3092|M.ulcerans_Agy99 RKLEFDKTGVIEALPRDRDTWVVIDDNAWFFALTDHVSIAEAEEFGQKLA MAV_2932|M.avium_104 RTLRFDDKGVIEALPRDRDTWMVIDEKPWFFALTDHLSVAEAEEFAQKLA MLBr_01543|M.leprae_Br4923 RTLRFDEKGVIDALPRDRDTWMVIDDKPWFFALADQLSFAEAEEFAQKLA Mflv_0327|M.gilvum_PYR-GCK RDQYSDPERPVLRISGGRIERWQNGTWASNIDSADHLGAADARHIARRLA Mvan_0413|M.vanbaalenii_PYR-1 RDQYPDPERPVLRVAARRIERWLNGSWVPFVDAADRMAPDDARHIARRLA MSMEG_0617|M.smegmatis_MC2_155 REQYPDPERPILRVADGRIERWQVGGWQPCVDVADAMSAAEAAHIARRLS MAB_3756c|M.abscessus_ATCC_199 LAAR----RGMQLELTERGLGAKGNVGSEVFAHPDHLTITEAMACARRLA TH_2597|M.thermoresistible__bu IRT-----DELLLDTGDRDR------------CTDSLSPVAALACARRLS Rv3894c|M.tuberculosis_H37Rv AATAVKAGRDGADADDDQRPAPLLRARGTFFAHADQLSIHRAYRYARAMA Mb3924c|M.bovis_AF2122/97 AATAVKAGRDGADADDDQRPAPLLRARGTFFAHADQLSIHRAYRYARAMA : .* : * .: :: MMAR_2665|M.marinum_M QWRLAEAYEEIGQRVAHIGARDILAYYGIDDPGNIDFDYLWGSRTDSMGR MUL_3092|M.ulcerans_Agy99 QWRLAEAYEEIGQRVAHIGARDILAYYGIDDPGNIDFDYLWGSRTDSMGR MAV_2932|M.avium_104 RWRLAEAYEEIGQRVAHIGARDILSYYGIEDPGNIDFDALWGGRTDTMGR MLBr_01543|M.leprae_Br4923 HWRPAEAYEEIGQRVAHIGARDILSYYGIGDPSAIDFDALWNSRTDAMGK Mflv_0327|M.gilvum_PYR-GCK RWDSNP----DHARSATTGGAAFTTLLGIPDASALDVAALWAPRNRDD-E Mvan_0413|M.vanbaalenii_PYR-1 RWDSNP----HHGRSASAGGAAFTTLLGIPDASALDVAALWAPRNRDD-E MSMEG_0617|M.smegmatis_MC2_155 RWDSNP----GYIRSTSTGSATFTTLLGIPDASALDVASLWAPRPRDE-E MAB_3756c|M.abscessus_ATCC_199 PYRVLTG-SGDEVQIQTEVSTRWSDIVGIGDPGLLNPEVVWRNRVGRD-R TH_2597|M.thermoresistible__bu AFRTAA--------VRNRSPWNWLELMDVDDPELL-PDTRWADTGGAG-A Rv3894c|M.tuberculosis_H37Rv RWSPTSR---SEVTDSTSGAAELLRSLGISDPRELDVDRLWAERRGRGDD Mb3924c|M.bovis_AF2122/97 RWSPTSR---SEVTDSTSGAAELLRSLGISDPRELDVDRLWAERRGRGDD : .: *. : * MMAR_2665|M.marinum_M SRLRAPFGNRSDNGELLFLDMKSLDEGGDGPHGVMSGTTGSGKSTLVRTV MUL_3092|M.ulcerans_Agy99 SRLRAPFGNRSDNGELLFLDMKSLDEGGDGPHGVMSGTTGSGKSTLVRTV MAV_2932|M.avium_104 SRLRAPFGVRSDNGELLFLDMKSLDEGGDGPHGVMSGTTGSGKSTLVRTV MLBr_01543|M.leprae_Br4923 SRLRVPFGNRSDNGELLFLDMKSLDEGGDGPHGVMSGTTGSGKSTLVRTV Mflv_0327|M.gilvum_PYR-GCK LR--VPIGVTAT-GEPLIFDLKDEAEGGMGPHGLMIGMTGSGKSQTLMSI Mvan_0413|M.vanbaalenii_PYR-1 LR--VPIGVTAT-GEPLIFDLKDEAEGGMGPHGLMIGMTGSGKSQTLMAI MSMEG_0617|M.smegmatis_MC2_155 LR--VPIGVTST-GEPLYFDLKDEAEGGMGPHGLMIGMTGSGKSQTLMSI MAB_3756c|M.abscessus_ATCC_199 LR--VPIGIAVD-GTPMELDIKEAAENGMGPHGLCIGATGSGKSEFLRTL TH_2597|M.thermoresistible__bu VLSPVPLGVSET-GARLDLDINEAARGGMGPHGLCVGATGSGKSELLRTL Rv3894c|M.tuberculosis_H37Rv RWCEIPVGAKPN-GELQNIILRAKDFGGFGFHSVVIGTSGSGKSELFLSL Mb3924c|M.bovis_AF2122/97 RWCEIPVGAKPN-GELQNIILRAKDFGGFGFHSVVIGTSGSGKSELFLSL *.* * : :. .* * *.: * :***** . :: MMAR_2665|M.marinum_M IESLMLGHPPEELQFVLADLKGGSAVKPFAGVPHVSRIITDLE-EDQALM MUL_3092|M.ulcerans_Agy99 IESLMLGHPPEELQFVLADLKGGSAVKPFAGVPHVSRIITDLE-EDQALM MAV_2932|M.avium_104 IESLMLSHPPEELQFVLADLKGGSAVKPFAGVPHVSRIITDLE-EDQALM MLBr_01543|M.leprae_Br4923 IESLMLAHPPEELQFVLADLKGGSAVKPFAGVPHVSRIITDLE-EDQVLM Mflv_0327|M.gilvum_PYR-GCK LLSLLTTHPADRLIVIYADFKGEAGADIFRNFPQVVAVISNMA-EKRSLA Mvan_0413|M.vanbaalenii_PYR-1 LLSLLTTHPADRLIVIYADFKGEAGADIFRNFPQVVAVISNMA-EKRSLA MSMEG_0617|M.smegmatis_MC2_155 LLSLLTTHPADRLIVIYADFKGEAGADIFRHFPQVVAVISNMA-EKRSLA MAB_3756c|M.abscessus_ATCC_199 TLGMIATHSPDALNLVLVDFKGGATFLGLDRAQHVAAIITNLA-EEANLV TH_2597|M.thermoresistible__bu VLGLITVHPPEVLNLILVDFKGGATFLGLERANHVSAVITNLS-DEAHLV Rv3894c|M.tuberculosis_H37Rv VYGIALTHSPETFNVIFVDMKFESAAQDILGIPHVVAALSNLGKDERHLA Mb3924c|M.bovis_AF2122/97 VYGIALTHSPETFNVIFVDMKFESAAQDILGIPHVVAALSNLGKDERHLA .: *..: : .: .*:* : : :* :::: :. * MMAR_2665|M.marinum_M ERFLDALWGEIARRKAICDSAGVD---DAKEYNSVRGRMRARGQDMAPLP MUL_3092|M.ulcerans_Agy99 ERFLDALWGEIARRKAICDSAGVD---DAKEYNSVRGRMRARGQDMAPLP MAV_2932|M.avium_104 ERFLDALWGEIARRKAICDSAGVD---DAKEYNAVRARMRARGQDMPPLP MLBr_01543|M.leprae_Br4923 ERFLDALWGEIARRKAVCDNAGVD---DAKEYNSVRTRMRARGQDMPALP Mflv_0327|M.gilvum_PYR-GCK DRFADTLRGEVARREQLLKDSGRRVQGSAFNSVTEYENAVREGHDLPPIP Mvan_0413|M.vanbaalenii_PYR-1 DRFADTLRGEVARREQLLLEAGRRIQNSAFNSVTEYENAIAEGHDLPPLP MSMEG_0617|M.smegmatis_MC2_155 DRFADTLRGEVARREQILKEAGRRVQGSAFNSVAEYESAIAAGHDLPPMP MAB_3756c|M.abscessus_ATCC_199 SRMKDALAGEMNRRQELLRAAGN------FANVTEYERARAAGASLSPLP TH_2597|M.thermoresistible__bu ARMYDALSGELNRRQELLRAAGN------AADLAEYTAARATRPDLPLLP Rv3894c|M.tuberculosis_H37Rv ERMRRVIDGEIKQRYELFKSVGAR-------DANDYEEIRLAGRDLPPVP Mb3924c|M.bovis_AF2122/97 ERMRRVIDGEIKQRYELFKSVGAR-------DANDYEEIRLAGRDLPPVP *: .: **: :* : * .:. :* MMAR_2665|M.marinum_M MLVVVIDEFYEWFRIMPTAVDVLDSIGRQGRAYWIHLMMASQTIES-RAE MUL_3092|M.ulcerans_Agy99 MLVVVIDEFYEWFRIMPTAVDVLDSIGRQGRAYWIHLMMASQTIES-RAE MAV_2932|M.avium_104 MLVVVIDEFYEWFRIMPTAVDVLDSIGRQGRAYWIHLMMASQTIES-RAE MLBr_01543|M.leprae_Br4923 MLVVVIDEFYEWFRIVPTAVDVLDSIGRQGRAYWIHLMMASQTIES-RAE Mflv_0327|M.gilvum_PYR-GCK TLLVVADEFTLMLADHPEYADLFDYVARKGRSFRIHLLFASQTLDVGRIK Mvan_0413|M.vanbaalenii_PYR-1 TLFVVADEFTLMLAEHPEYADLFDYVARKGRSFRIHLLFASQTLDVGRIK MSMEG_0617|M.smegmatis_MC2_155 TLFVVADEFTLMLAEHPEYADLFDYVARKGRSFRIHLLFASQTLDVGRIK MAB_3756c|M.abscessus_ATCC_199 ALFIIVDEFSELLSQHPDFAELFVAIGRLGRSLHVHLLLASQRLDEGRLR TH_2597|M.thermoresistible__bu ALLIAVDEFSELLAQHPEFAELFVAIGRLGRSLGMHLLLSSQRVDEGRLR Rv3894c|M.tuberculosis_H37Rv VLLVIVDEYLELFANHKKWIDLIIHIGQEGRGANVFFMLGGQRLDLSSLQ Mb3924c|M.bovis_AF2122/97 VLLVIVDEYLELFANHKKWIDLIIHIGQEGRGANVFFMLGGQRLDLSSLQ *.: **: : ::: :.: **. :.:::..* :: . MMAR_2665|M.marinum_M KLMENMGYRLVLKARTAG-AAQAAGVPNAVNLP----AQAGLGYFRKSLE MUL_3092|M.ulcerans_Agy99 KLMENMGYRLVLKARTAG-AAQAAGVPNAVNLP----AQAGLGYFRKSLE MAV_2932|M.avium_104 KLMENMGYRLVLKARTAG-AAQAAGVPNAVNLP----AQAGLGYFRRSLE MLBr_01543|M.leprae_Br4923 KLMENMGYRLVLKARTAG-AAQAAGVPNAVNLP----AQAGLGYFRKSLE Mflv_0327|M.gilvum_PYR-GCK DIDKNTSYRIGLKVASPSVSRQIIGVEDAYHIESGREHKGVGFLVPAPGA Mvan_0413|M.vanbaalenii_PYR-1 DIDKNTSYRIGLKVASPAVSRQIIGVEDAYHIESGREHKGEGFLVPAPGA MSMEG_0617|M.smegmatis_MC2_155 DIDKNTSYRIGLKVASPSISRQIIGVEDAYHIESGREHKGEGFLVPAPGA MAB_3756c|M.abscessus_ATCC_199 GLESHLSYRLCLKTFSANESRAAIGVPDAYHLP----NTPGSCYLKDDSG TH_2597|M.thermoresistible__bu GLETHLSYRICLKTFSAGDSRAVLGVPDAYQLP----ARPGAALLKTVSD Rv3894c|M.tuberculosis_H37Rv KVKSNIAFRIALRAESGDDSREVIGSDAAYHLPS---KENGFALLKVGPR Mb3924c|M.bovis_AF2122/97 KVKSNIAFRIALRAESGDDSREVIGSDAAYHLPS---KENGFALLKVGPR : : .:*: *:. : : * * :: . MMAR_2665|M.marinum_M DIIRFQAEFLWRDYFQPGITVDGEEAPVLVHSIDYIRPQLFTNSFTPLEV MUL_3092|M.ulcerans_Agy99 DIIRFQAEFLWRDYFQPGITVDGEEAPVLVHSIDYIRPQLFTNSFTPLEV MAV_2932|M.avium_104 DIVRFQAEFLWRDYFPRGISDDGEEAPALVHSIDYVRPQLFTNSFTPLEV MLBr_01543|M.leprae_Br4923 DVIRFQAEFLWRDYFR-GVTLDGEEQPVLVHNIDYVRPQLFTNLFTPLEV Mflv_0327|M.gilvum_PYR-GCK LPVKFRSTYVDGIYEP--PRVDRSIVVHAIP-----KPQLFSAGWVDPEP Mvan_0413|M.vanbaalenii_PYR-1 LPIKFRSTYVDGIYEP--PRVDRSIVVHAIP-----KPQLFSAGWVDPEP MSMEG_0617|M.smegmatis_MC2_155 VPIKFRSTYVDGIYDP--PRAEKSIVVHALP-----QPQVFTAGRVEPEP MAB_3756c|M.abscessus_ATCC_199 ELTRFQTSYVSGPYVPYGPARRTVSSGGGGA-----APRLFTAAPVALQM TH_2597|M.thermoresistible__bu ELVRFQTAYVSG------PLLRTREKPAEPD-----APRVFTPEPAAASA Rv3894c|M.tuberculosis_H37Rv DLEPFRCFYLSAPFVVPKKKEVARTIDMTLT-----QPRLYDWQYQPLDA Mb3924c|M.bovis_AF2122/97 DLEPFRCFYLSAPFVVPKKKEVARTIDMTLT-----QPRLYDWQYQPLDA *: :: *::: . MMAR_2665|M.marinum_M TVGGPEIDKVVAHANGEVVEEVEAEAE--EEGIRV----------PKVGT MUL_3092|M.ulcerans_Agy99 TVGGPEIDKVVAHANGEVVEEAEAEAEAEEEGIRV----------PKVGT MAV_2932|M.avium_104 SVGGPDVTVPAIPAAGADMPEIEGPDDDDVEGIRT----------PKVGT MLBr_01543|M.leprae_Br4923 SVGGPEVDAEAVFANAQEFDEEIAEEEA-EGGVRT----------PKIGT Mflv_0327|M.gilvum_PYR-GCK D-------------------TVIVDDGADVEVLPP----------RKLIA Mvan_0413|M.vanbaalenii_PYR-1 D-------------------TVIVDDGADVEVLPP----------RKLIT MSMEG_0617|M.smegmatis_MC2_155 D-------------------TVIATGDVEVHTAPP----------RKLIA MAB_3756c|M.abscessus_ATCC_199 RPA-----------------EVVEDDSPAVSEATG----------RSVID TH_2597|M.thermoresistible__bu D--------------------------RMRSDGPV----------RTLLD Rv3894c|M.tuberculosis_H37Rv ADA-----------------EALATAAAADAEPDEFLYYDDGFKKKKIVD Mb3924c|M.bovis_AF2122/97 RRR-----------------RGIGDRRGRRCG-------------TRRIP MMAR_2665|M.marinum_M VIIDQLRRIN-FEPYRLWQPPLTQPVAIDDLVNRFLGHPWQKEYGSARNL MUL_3092|M.ulcerans_Agy99 VIIDQLRRIN-FEPYRLWQPPLTQPVAIDDLVNWFLGHPWQKEYGSARNL MAV_2932|M.avium_104 VIIDQLRKID-FQPYRLWQPPLDQPIAIDELVNRFLGHPWQQDYGTARDL MLBr_01543|M.leprae_Br4923 VIIDQLRRID-FEPYRLWQPPLTQPVAIDDLVNRFLGHPWQKDYGSARNL Mflv_0327|M.gilvum_PYR-GCK TIGEQLVHYG-PRAPQLWLPPLEEAIPLQGLLERSGIGA--------GQW Mvan_0413|M.vanbaalenii_PYR-1 TIGEQLAQYG-PRAPQLWLPPLDEPIPLRDVLERAGVGA--------RQW MSMEG_0617|M.smegmatis_MC2_155 TIGDQLAAYG-PKAPQLWLPPLDEPIALADVLAGADVEP--------GQL MAB_3756c|M.abscessus_ATCC_199 TILDRVEGHG-NPAHEVWLPPLDDSPTLGDLIP-RHGRAGFDAV---GSL TH_2597|M.thermoresistible__bu TVVDRLAGHG-TAAHRVWLEPLSASPPLGALLSARHG----------APL Rv3894c|M.tuberculosis_H37Rv VLRESLYNVPHRSPRRPWLAPLEDPEPVDRLVAAYRGKPWHVDYGQNPGL Mb3924c|M.bovis_AF2122/97 LLRRRFQ------------------EEEDRRRAAG--------------- : . MMAR_2665|M.marinum_M VFPIGVIDRPFKHDQPPWTVDTSGPGSNVLILGAGGSGKTTALQTLISSA MUL_3092|M.ulcerans_Agy99 VFPIGVIDRPFKHDQPPWTVDTSGPGSNVLILGAGGSGKTTALQTLISSA MAV_2932|M.avium_104 VFPIGIIDRPFKHDQPPWTVDTSGPGANVLILGAGGSGKTTALQTLICSA MLBr_01543|M.leprae_Br4923 VFPIGVIDRPFKHDQPAWTVDTSGPGSNVLVLGAGGSGKTTALQTIICSA Mflv_0327|M.gilvum_PYR-GCK RWPLGEIDRPFDMRRDPLVFDATSAAANMVIHGGPKSGKSTALQTFVLSA Mvan_0413|M.vanbaalenii_PYR-1 RWPLGEIDRPFEMRRDPLIFDATSAAANMVIHGGPKSGKSSALQTFVLSA MSMEG_0617|M.smegmatis_MC2_155 RWPLGEIDKPFEMRRDVLVYDAHTAAANVLIHGGPRSGKSTALQAFVLSA MAB_3756c|M.abscessus_ATCC_199 TVPIGIVDRPYEQRRDPYIVDLSAAAGNVAIVGAPQSGKSMAVRTLVTSL TH_2597|M.thermoresistible__bu TVPIGVVDCPFEQRRIPLVAALAGADGNVAVVGGPQSGKSTVVRTLVMAL Rv3894c|M.tuberculosis_H37Rv MFPVGVMDIPEESQQ--VVHAVDALRSNIIVVGAKQRGKTTTLMALMCSA Mb3924c|M.bovis_AF2122/97 -----------------VAIQRAAPIAAPAVVGAAGRPRAGR-------- . : *. :: MMAR_2665|M.marinum_M ALTHTPDQVQFYCLAYSSTALTTVSKLPHVGEVAGPTDPYGVRRTVAELL MUL_3092|M.ulcerans_Agy99 ALTHTPDQVQVYCLAYSSTALTTVSKLPHVGEVAGPTDPYGVRRTVAELL MAV_2932|M.avium_104 ALTHTPEQVQFYCLAYSSTALTTVARLPHVGEVVGPTDPYGVRRTVAELL MLBr_01543|M.leprae_Br4923 ALTHTPEQVQFYCLGYSGTALTTVAHLPHVGEVAGPTDPYGVRRTVAELL Mflv_0327|M.gilvum_PYR-GCK AALHAPGDVSFYCLDYGGGQLRVLDGLAHVGSVASPLESERIRRTFGELE Mvan_0413|M.vanbaalenii_PYR-1 AALHAPGDVSFYCLDYGGGQLRALENLAHVGSVASPLEPERIRRTFGELE MSMEG_0617|M.smegmatis_MC2_155 AALHSPRAITFYCLDYGGGKLADLADLAHVGSVATPLEPERIRRTFGELE MAB_3756c|M.abscessus_ATCC_199 AVTHSPAQVQFYCLDFGGGTLTSLAQLPHVGSVASRLESDLIRRTFAEML TH_2597|M.thermoresistible__bu AATHDPRDVQVYCVDCGGGALTALSALPHVGAVAGRGDAELISRIVAVLE Rv3894c|M.tuberculosis_H37Rv ATMYTPERVTFFCIGG--ATMAQIGSLPHVTDIVSPKDAEGIERILSTMD Mb3924c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_2665|M.marinum_M ALVRERKRSFLEYGIASMEMFRRRKFGGEAGP---VPNDGFGDVYLVIDN MUL_3092|M.ulcerans_Agy99 ALVRERKRSFLEYGIASMEMFRRRKFGGEAGP---VPNDGFGDVYLVIDN MAV_2932|M.avium_104 ALVRERKRSFLEYGIPSMEVFRRRKFGGEPGP---VPNDGFGDVYLVVDN MLBr_01543|M.leprae_Br4923 ALVRDRKRSFLEHGIASMEVFRRRKFGGELGP---VPNDGFGDVYLVIDN Mflv_0327|M.gilvum_PYR-GCK QLLQARQRHGAAVNNGGYR-------------------DGYGEVFLLIDN Mvan_0413|M.vanbaalenii_PYR-1 HLLRARQQHGAAAADGQYR-------------------DGYGEVFLLIDN MSMEG_0617|M.smegmatis_MC2_155 QLLRARQRQGAVNRTGSYT-------------------DGYGEVFLVIDN MAB_3756c|M.abscessus_ATCC_199 TIVRSRENAFRAYGIDSMAEYRRRKGAGDP-Q---LANDPFGDVFFIIDG TH_2597|M.thermoresistible__bu KILADRETRFRAAGVDSMAERRRRR----------QRDDPYGDVFLVIDG Rv3894c|M.tuberculosis_H37Rv ALIDAREEAFRRAKIDMDGFRERRFGIGGDGVGGTDPTDAFGDVFVVLDD Mb3924c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_2665|M.marinum_M YRALAE-------ENEVLIEQVNLIINQGPSFGVHVVVTADRES-ELRPP MUL_3092|M.ulcerans_Agy99 YRALAE-------ENEVLIEQVNLIINQGPSFGVHVVVTADRES-ELRPP MAV_2932|M.avium_104 YRALAE-------ENEVLIEQVNVIINQGPSFGVHVVVTADRES-ELRPP MLBr_01543|M.leprae_Br4923 YRALVE-------ENEVLIEQVNQIINQGPSFGVHVVVTADRES-ELRPQ Mflv_0327|M.gilvum_PYR-GCK LYAFSRDNTDTFNTRNPLLAKVTELVNTGLAYGIHVVITTPNWL-EVPLA Mvan_0413|M.vanbaalenii_PYR-1 LYAFSRDNTDTFNARNPLLARVTELVNTGLSYGIHVVVTTPNWL-EVPLT MSMEG_0617|M.smegmatis_MC2_155 LYAFSRDNTDTFNTRNPLLAKVTELANSGLAYGIHVVITTPNWL-EVPLA MAB_3756c|M.abscessus_ATCC_199 WSTVR-------QEFEALEPQVTALAAQGLGFGVHTVVTASRWA-EIRPA TH_2597|M.thermoresistible__bu IAVIR-------NEFDTIEPRIAALAAQGLGYGVHVVVTASRWA-ELRPV Rv3894c|M.tuberculosis_H37Rv YDDLYA-------KDTLLGDRIISLSSRGPEYGVHLMCSAGGWIHGQRQS Mb3924c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_2665|M.marinum_M VRSGFGSRVELRLAAVEDAK--------LVRSRFAKDVPVKPGR-----G MUL_3092|M.ulcerans_Agy99 VRSGFGSRVELRLAAVEDAK--------LVRSRFAKDVPVKPGR-----G MAV_2932|M.avium_104 VRSGFGSRVELRLAAVEDAK--------LVRSRFAKDVPVKPGR-----G MLBr_01543|M.leprae_Br4923 VRSGFGSRVELRLAAVEDAK--------LVRSRFAKDVPVQSGR-----G Mflv_0327|M.gilvum_PYR-GCK MRDGLGLRLELRLHDAHDSNVRVVG---ALRRPAEGVPADQPGR-----G Mvan_0413|M.vanbaalenii_PYR-1 MRDGLGLRLELRLHDPRDSNVRVVSKDAALRRPAESVPADQPGR-----G MSMEG_0617|M.smegmatis_MC2_155 MRDGLGLRLELKLHDSHDSIVRVAG---ALRRPADSVPADQPGR-----G MAB_3756c|M.abscessus_ATCC_199 LKDQIGTRVELRLGDPLDS--------DFDRKLAQLVPDGRPGR-----G TH_2597|M.thermoresistible__bu LKDQLGTRIELRLGDPADS--------EMDRRRARHLIDSPPGR-----G Rv3894c|M.tuberculosis_H37Rv LLQNVTARIQLRLADPGESQMGHLS---IESREAARRTLNRPGFGLTES- Mb3924c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_2665|M.marinum_M MVAVNYVRLDSDPQAGLHTLVARPAMGSTPTNV----FECDSVVAAVSRL MUL_3092|M.ulcerans_Agy99 MVAVNYVRLDSDPQAGLHTLVARPAMGSTPTNV----FECDSVVAAVSRL MAV_2932|M.avium_104 MVAVNYVRLDADPQSGLHTLVARPALASTPDNR----FESDSVVEAVSRL MLBr_01543|M.leprae_Br4923 MVAVNYVRLDSDPQAGLHTLVARPALANTPANV----FESDSVVAPVSRL Mflv_0327|M.gilvum_PYR-GCK LTMA-----------AEHFLFARPAPETIP--------------ALNARF Mvan_0413|M.vanbaalenii_PYR-1 LTMA-----------VEHFLFAAPATESIP--------------ALNARY MSMEG_0617|M.smegmatis_MC2_155 LTMA-----------AEHFLFAEPALSDIA--------------VINARY MAB_3756c|M.abscessus_ATCC_199 ITRD-----------RRHMLIGLPRVDSISSNQDLGEAIAAAAASMRQR- TH_2597|M.thermoresistible__bu ITRD-----------GRELTIALPRLDEAASTTGLAASIAASAQALHIRY Rv3894c|M.tuberculosis_H37Rv ---------------LHELRIGVPALADPGTGELVG--ITDVGARIADVA Mb3924c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_2665|M.marinum_M TTSQAPPVRRLPASFGVDQVRQLAARDTRQGVGVGGIAWAISELDLQPVY MUL_3092|M.ulcerans_Agy99 TTSQAPPVRRLPASFGVDQVRQLAARDTRQGVGVGGIAWAISELDLQPVY MAV_2932|M.avium_104 ATGQAPPVRRLPATFGLDQLRELAAQDTRQGVGAGGIAWAISELDLSPVY MLBr_01543|M.leprae_Br4923 TSAQAPPVRRLPARFGMEQVRERAVRDTRQGVGVGGIAWAISELDLQPVY Mflv_0327|M.gilvum_PYR-GCK PGQSAPEVRLLPTRLSPRAFASLYPAPER-------VVIGQREEDLAAVS Mvan_0413|M.vanbaalenii_PYR-1 PGRSAPPVRLLPTDLSPSAFPTLYPAPER-------VVVGQREEDLAAVT MSMEG_0617|M.smegmatis_MC2_155 PGVSAPPVRLLPTDLSPDALAPLYPAPET-------VVIGQREEDLAPVA MAB_3756c|M.abscessus_ATCC_199 SSVEAPQVRMLPHKIDYAALVPQAPQNDQP---NLRILVGINESELAPTF TH_2597|M.thermoresistible__bu QQRTAPPVELLPGRVDHETVLAAASEVQR-----ARTILGLGETDLEPVT Rv3894c|M.tuberculosis_H37Rv GVTKHASLQRLPQRVELSAIVEHEAVHQGGDDLSIAFAIG-ERHELGPVP Mb3924c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_2665|M.marinum_M LNFAENSHLMVTGRRECGRTTTLATIMSEIGRLYAPGATSVPAPPPGQPS MUL_3092|M.ulcerans_Agy99 LNFAENSHLMVTGRRECGRTTTLATIMSEIGRLYAPGATSVPAPPPGQPS MAV_2932|M.avium_104 LNFDENAHLMVTGRRECGRTTTLATIMKEIGRLYAPGASSAPTPPAGQPS MLBr_01543|M.leprae_Br4923 LNFAENAHLMITGRRECGRTTVLATIMSEIGRLYAPGGTSAP--PTSERS Mflv_0327|M.gilvum_PYR-GCK VDFADNPLLMVFGDTKTGKTTLLRHLIRTLRENSRA------------DQ Mvan_0413|M.vanbaalenii_PYR-1 VDFGDNPLMMVFGDAKTGKTTLLRHLIRTIRENSRP------------DQ MSMEG_0617|M.smegmatis_MC2_155 VDFANHPLLMVFGDSKSGKTTLLRHIIRTVRENSTP------------DQ MAB_3756c|M.abscessus_ATCC_199 LEFGEQPHMMIFGDSECGKTALLRTMCREIVRTTTP------------QQ TH_2597|M.thermoresistible__bu LDLTEQPHLVMLGDPRSGKTAALRTVCREILRTHSP------------TA Rv3894c|M.tuberculosis_H37Rv IKLRESPGLMILGRQGCGKTTALVAIGEAVMNRFSP------------QQ Mb3924c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_2665|M.marinum_M AQVWLIDPRRQ---LLTALGSNYVERFAYNLDGVQAMMGELAAVLAG-RE MUL_3092|M.ulcerans_Agy99 AQVWLIDPRRQ---LLTALGSNYVERFAYNLDGVQAKMGELAAVLAG-RE MAV_2932|M.avium_104 AQVWLVDPRRQ---LLTTLGSDYVEKFAYNLDGVQAMMGELAAALAG-RE MLBr_01543|M.leprae_Br4923 AQVWLIDPRRQ---LLTMLGSNYMEKFAYNLDGVSAMVGELAALLAS-RE Mflv_0327|M.gilvum_PYR-GCK VAFTVIDRRLQ---LVDEPIFPDN-EYTPNIDRILPAMLGLAGLLEK-RR Mvan_0413|M.vanbaalenii_PYR-1 VAFTVIDRRLQ---LVDEPIFPDN-EYTPNIDRITPAMLGLSALLEK-RR MSMEG_0617|M.smegmatis_MC2_155 VAFTVIDRRLH---LVDEPLFPDN-EYTANIDRVLPAMLGLSALIEK-RR MAB_3756c|M.abscessus_ATCC_199 AQLFIVDYRRT---LLGVVETEHLAKYAMSSNTLVDEVPALIELLKS-RM TH_2597|M.thermoresistible__bu AQLLLVDFRRT---LLGVVETEHLGAYAMSPPTLQTALAGLVDRLRA-RL Rv3894c|M.tuberculosis_H37Rv AQLTLIDPKTAPHGLRDLHAPGYVRAYAYDQDEIDEVITELAQQILLPRL Mb3924c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_2665|M.marinum_M PPPGLSAEELLSRSWWSG------PEIFLIVDDIQQLPPGFDSP------ MUL_3092|M.ulcerans_Agy99 PPPGLSAEELLSRSWWSG------PEIFLIVDDIQQLPPGFDSP------ MAV_2932|M.avium_104 PPPGLSAEELLSRNWWSG------PEIFLIVDDIQQLPAGFDSP------ MLBr_01543|M.leprae_Br4923 PPPDLSAEELLSRSWWSG------PEIFLIIDDIQQLPPSFDSP------ Mflv_0327|M.gilvum_PYR-GCK PPAGLSPQELRGWDFRSSANGSGSHLHYLIIDDVDQIPDGPAVSGPYAGQ Mvan_0413|M.vanbaalenii_PYR-1 PPAGLSPQELSRWDFRAGANGSGRHLHYLIIDDVDQIPDGPAISGPFAGQ MSMEG_0617|M.smegmatis_MC2_155 PPAGLSAQELSRWTYTG-------HTHYLIVDDVDQIPDTPAVSGPFVGQ MAB_3756c|M.abscessus_ATCC_199 PGPDVTQQELRDRSWWSG------PEIYILVDDYDLVALASGNP------ TH_2597|M.thermoresistible__bu PDAAVTQRQLRDRSWWTG------PELFLVIDDYDLVAESAAAA------ Rv3894c|M.tuberculosis_H37Rv PPKGLSQEELRALKPWEG------PRHFVLIDDVQDLRPAQSYPQKPPVG Mb3924c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_2665|M.marinum_M --LHKAAPWVNRAADVGLHVIVTRSFGG-WSSAGSDPMLRALHQANAPLL MUL_3092|M.ulcerans_Agy99 --LHKAAPWVNRAADVGLHVIVTRSFGG-WSSAGSDPMLRALHQANAPLL MAV_2932|M.avium_104 --LHKAAPWVTRAADVGLHVIVTRTFGG-WSSAGSDPMLRALAQANAPLL MLBr_01543|M.leprae_Br4923 --LQKVVPWVTRAGDVGLHVIATRTFGG-WSSAGSDPMLRALHQANAPLL Mflv_0327|M.gilvum_PYR-GCK RPWTPVIGLLSQASELGLRVIVTARAAGSAHAVMTAPLLRRLNELQATTL Mvan_0413|M.vanbaalenii_PYR-1 RPWTALIGLLAQASDLGLRVIVTARAAGSAHAVMTAPLLRRLNDLQATTF MSMEG_0617|M.smegmatis_MC2_155 RPWTNIVGLLAEAADLGLRVIVTARATGSAHAVMTAPLLRRLNDLQATTL MAB_3756c|M.abscessus_ATCC_199 --LLPLAEYLPHSKDIGLHVVIARRTSG-ASRAMFEPMMARMKDLSCIGL TH_2597|M.thermoresistible__bu --LTPVTELLPHGRDIGLHVIVARRAGG-AARAMFDPLPARLRETGAAGL Rv3894c|M.tuberculosis_H37Rv ---AALWKLMERARQVGLHVFSTRNSAN-WATMPMDPWVKSQTSAKVAQL Mb3924c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_2665|M.marinum_M VMDADPDEGFIRGKMKGGPLPRGRGLLMAEDTGVFVQVALTEVRK----- MUL_3092|M.ulcerans_Agy99 VMDADPDEGFIRGKMKGGPLPRGRGLLMAEDTGVFVQVALTEVRK----- MAV_2932|M.avium_104 VMDADPDEGFIRGKMKGGPLPRGRGLLMAEDTGVFVQVAATEFRK----- MLBr_01543|M.leprae_Br4923 VMDADPDEGFIRGKMKGGPLPRGRGLLMAEDTGVLVQVAETDMRR----- Mflv_0327|M.gilvum_PYR-GCK LLSGNPQDSGKIRGHRFSRLPAGRGLLLDDSNLSDTPTYVQLVDPLADDA Mvan_0413|M.vanbaalenii_PYR-1 LLSGNPADSGKIRGHRFARLPVGRAMLLDDRNSSGSPTFVQLVNPLAERT MSMEG_0617|M.smegmatis_MC2_155 MLSGNPTDSGKIRGHRFARFPAGRGLLLTD---TDTPDHIQLVNPLGDAA MAB_3756c|M.abscessus_ATCC_199 QMSGNKDEGVLLGTVRPSEQPPGRGTLVMRSGGQQLIQVAWSEPQ----- TH_2597|M.thermoresistible__bu MLSAPPEEGQLWGSVRATPLPPGRATLLTRGRPAQLIQVSWIEPP----- Rv3894c|M.tuberculosis_H37Rv YMDNDPQNRINR-SVRAQTLPPGRGLLVGADGDVEGILVGYPSVPGEQ-- Mb3924c|M.bovis_AF2122/97 -------------------------------------------------- MMAR_2665|M.marinum_M ------------------ MUL_3092|M.ulcerans_Agy99 ------------------ MAV_2932|M.avium_104 ------------------ MLBr_01543|M.leprae_Br4923 ------------------ Mflv_0327|M.gilvum_PYR-GCK TAP------AGHLGKEYS Mvan_0413|M.vanbaalenii_PYR-1 AAR------SGHSGKEYS MSMEG_0617|M.smegmatis_MC2_155 LSGNIGNNGNHNRGGEYR MAB_3756c|M.abscessus_ATCC_199 ------------------ TH_2597|M.thermoresistible__bu ------------------ Rv3894c|M.tuberculosis_H37Rv ------------------ Mb3924c|M.bovis_AF2122/97 ------------------