For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
IKPENIVLPTPLSIPPPEGKPWWLVVVGVLVVGLLIGMVGMTFASGSHVFGGAGAIFPIFMIGGVAMMMF GGRFGGQQQMSRPKLDSMRAQFMLMLDMLRETAHESADSMDANYRWFHPAPTTLAAAVGSPRMWERKPDG KDLNFGVVRVGVGMTRPEVTWGEPQNMPTDIELEPVTGKALQEFGRYQSVVYNLPKMISLLVEPWYSLAG DREQVLGLMRAIICQLTFSHGPDHVRMIVVSSDLDEWDWVKWLPHFGDPRRQDAAGNARMVYSSVREFAA EQAELFAGRGSFTPRHASSSAQTPTPHTVIIADAVDPQWEYVISAEGVDGVTFFDLTGSSMWSSVPERTL RFDDKGVIEALPRDRDTWMVIDEKPWFFALTDHLSVAEAEEFAQKLARWRLAEAYEEIGQRVAHIGARDI LSYYGIEDPGNIDFDALWGGRTDTMGRSRLRAPFGVRSDNGELLFLDMKSLDEGGDGPHGVMSGTTGSGK STLVRTVIESLMLSHPPEELQFVLADLKGGSAVKPFAGVPHVSRIITDLEEDQALMERFLDALWGEIARR KAICDSAGVDDAKEYNAVRARMRARGQDMPPLPMLVVVIDEFYEWFRIMPTAVDVLDSIGRQGRAYWIHL MMASQTIESRAEKLMENMGYRLVLKARTAGAAQAAGVPNAVNLPAQAGLGYFRRSLEDIVRFQAEFLWRD YFPRGISDDGEEAPALVHSIDYVRPQLFTNSFTPLEVSVGGPDVTVPAIPAAGADMPEIEGPDDDDVEGI RTPKVGTVIIDQLRKIDFQPYRLWQPPLDQPIAIDELVNRFLGHPWQQDYGTARDLVFPIGIIDRPFKHD QPPWTVDTSGPGANVLILGAGGSGKTTALQTLICSAALTHTPEQVQFYCLAYSSTALTTVARLPHVGEVV GPTDPYGVRRTVAELLALVRERKRSFLEYGIPSMEVFRRRKFGGEPGPVPNDGFGDVYLVVDNYRALAEE NEVLIEQVNVIINQGPSFGVHVVVTADRESELRPPVRSGFGSRVELRLAAVEDAKLVRSRFAKDVPVKPG RGMVAVNYVRLDADPQSGLHTLVARPALASTPDNRFESDSVVEAVSRLATGQAPPVRRLPATFGLDQLRE LAAQDTRQGVGAGGIAWAISELDLSPVYLNFDENAHLMVTGRRECGRTTTLATIMKEIGRLYAPGASSAP TPPAGQPSAQVWLVDPRRQLLTTLGSDYVEKFAYNLDGVQAMMGELAAALAGREPPPGLSAEELLSRNWW SGPEIFLIVDDIQQLPAGFDSPLHKAAPWVTRAADVGLHVIVTRTFGGWSSAGSDPMLRALAQANAPLLV MDADPDEGFIRGKMKGGPLPRGRGLLMAEDTGVFVQVAATEFRK*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_2932 | - | - | 100% (1375) | ftsk/SpoIIIE family protein |
M. avium 104 | MAV_4390 | - | e-163 | 32.60% (1365) | ftsk/SpoIIIE family protein |
M. avium 104 | MAV_3639 | - | 1e-11 | 26.36% (220) | FtsK/SpoIIIE family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1812 | - | 0.0 | 90.13% (1378) | hypothetical protein Mb1812 |
M. gilvum PYR-GCK | Mflv_0327 | - | 1e-139 | 30.85% (1397) | cell divisionFtsK/SpoIIIE |
M. tuberculosis H37Rv | Rv1784 | - | 0.0 | 90.46% (933) | hypothetical protein Rv1784 |
M. leprae Br4923 | MLBr_01543 | - | 0.0 | 86.81% (1349) | putative SpoIIIE-family membrane protein |
M. abscessus ATCC 19977 | MAB_3756c | - | 0.0 | 32.97% (1386) | putative FtsK/SpoIIIE family protein |
M. marinum M | MMAR_2665 | - | 0.0 | 89.32% (1376) | FtsK/SpoIIIE family protein |
M. smegmatis MC2 155 | MSMEG_1536 | - | 1e-156 | 30.88% (1360) | ftsk/SpoIIIE family protein |
M. thermoresistible (build 8) | TH_2597 | - | 1e-152 | 30.62% (1339) | PUTATIVE cell divisionFtsK/SpoIIIE |
M. ulcerans Agy99 | MUL_3092 | - | 0.0 | 89.03% (1376) | FtsK/SpoIIIE family protein |
M. vanbaalenii PYR-1 | Mvan_0413 | - | 1e-143 | 30.24% (1412) | cell divisionFtsK/SpoIIIE |
CLUSTAL 2.0.9 multiple sequence alignment Mb1812|M.bovis_AF2122/97 -MKRGFARPTPEKPPVIKPENIVLSTPLSIPPPEGKPWWLIVVGVVVVGL Rv1784|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2665|M.marinum_M -MKRGFARPTPEKAPVIKPENIVLPTPLSIPPPEGKPWWLIVVGVVVVGL MUL_3092|M.ulcerans_Agy99 -MKRGFARPTPEKAPVIKPENIVLPTPLSIPPPEGKPWWLIVVGVVVVGL MAV_2932|M.avium_104 ---------------MIKPENIVLPTPLSIPPPEGKPWWLVVVGVLVVGL MLBr_01543|M.leprae_Br4923 -----------------------------------------MIGVVVIGL MSMEG_1536|M.smegmatis_MC2_155 --------MEKTGRSDAGTGEVLIDAPPEVPRATPVPVVTRVLPVVLVVA TH_2597|M.thermoresistible__bu -----------------------------VPRELPANPVARLLPLVMVVA MAB_3756c|M.abscessus_ATCC_199 ----------------MPGGEVNVQPPPEIPRPVPSPIIAKIMPLVMVVA Mflv_0327|M.gilvum_PYR-GCK MSRLIFEHRKRLPAPVARKGTITIEPPPELPRVVPPSLLRRALPYLIVIL Mvan_0413|M.vanbaalenii_PYR-1 MSRLIFEHRKRVPAPVVPKGTITIEPPPELPRVIPPSLLRRALPYLIVIL Mb1812|M.bovis_AF2122/97 LGGMVAMVFASGS----HVFGGIGSIFPLFMMVGIMMMMFRGM-GGGQQQ Rv1784|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2665|M.marinum_M LGGMVAMVFASGS----HVFGGVGSIFPIFMMVGIMMMMFRSVGAGGQQQ MUL_3092|M.ulcerans_Agy99 LGGMVAMVFASGS----HVFGGVGSIFPIFMMVGIMMMMFRSVGAGGQQQ MAV_2932|M.avium_104 LIGMVGMTFASGS----HVFGGAGAIFPIFMIGGVAMMMFGGR-FGGQQQ MLBr_01543|M.leprae_Br4923 VGGMVAMTFASGS----RVFGGAGSIFPLFMIGGVAMMMFSGR-MGGQQQ MSMEG_1536|M.smegmatis_MC2_155 MVGMMVVYFRS-------GVATGRGPAVMFFPAMMAMSVLATLAYSLRGN TH_2597|M.thermoresistible__bu MAGMLVLYFTS-------GNSAMRTPVFSFFPVLMVASAVGTLAYGARGT MAB_3756c|M.abscessus_ATCC_199 MVGMIAFFVTSGSFGGGAGGGMMRSPMFMLFPIMMMVSMVSMVSNSGGKG Mflv_0327|M.gilvum_PYR-GCK IVGMIVALVATGLR---------LISPTTLFFPFVLLLAATALYRGTDNK Mvan_0413|M.vanbaalenii_PYR-1 IVGMIVALVATGLR---------MISPTMLFFPFVLLLAATALYRGTDNK Mb1812|M.bovis_AF2122/97 MSRPKLDAMRAQFMLMLDMLRETAQESADSMDANYRWFHPAPNTLAAAVG Rv1784|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2665|M.marinum_M MSRPKLDAMRAQFMLMLDMLRETAQESADSMDSNYRWFHPAPSTLAAAVG MUL_3092|M.ulcerans_Agy99 MSRPKLDAMRAQFMLMLDMLRETAQESADSMDSNYRWFHPAPSTLAAAVG MAV_2932|M.avium_104 MSRPKLDSMRAQFMLMLDMLRETAHESADSMDANYRWFHPAPTTLAAAVG MLBr_01543|M.leprae_Br4923 MSRPKLDAMRAQFMLMLDMLREAANESADSMDANYRWFHPAPTTLAAAVG MSMEG_1536|M.smegmatis_MC2_155 GGSAELERDRREYLRYLDGLDVLAAETARAQWQMLHDTFPEPAVLWMLAD TH_2597|M.thermoresistible__bu HRTAELNADRRQYLRHLDELDRQAAAAATAQQRSLHRRHPRPDALWTLAG MAB_3756c|M.abscessus_ATCC_199 AKTSEINEDRKDYLRYLEVVRKNVTDTGAAQRKALLWNNPDPSALWTLAG Mflv_0327|M.gilvum_PYR-GCK MRTEEVDAERADYLRYLSVVRDNVRAHADEQRTALQWSHPEPAALNGIPG Mvan_0413|M.vanbaalenii_PYR-1 MRTEEVDAERADYLRYLSVVRDNVRAYADQQRAALQWSHPEPAALVSIPG Mb1812|M.bovis_AF2122/97 SPRMWERKPDGKDLNFGVVRVGVGMTRPEVTWGEPQNMPTDIELEPVTGK Rv1784|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2665|M.marinum_M SPRMWERKPDGKDLNFGVVRVGVGMTRPEVTWGEPQNMPTDIELEPVTGK MUL_3092|M.ulcerans_Agy99 SPRMWERKPDGKDLNFGVVRVGVGMTRPEVTWGEPQNMPTDIELEPVTGK MAV_2932|M.avium_104 SPRMWERKPDGKDLNFGVVRVGVGMTRPEVTWGEPQNMPTDIELEPVTGK MLBr_01543|M.leprae_Br4923 SSRMWERKPDGKDLNFCVVRVGVGMTRPEVTWGEPQNMPTDIELEPVTGK MSMEG_1536|M.smegmatis_MC2_155 SDRRWERDTE--HRHFLEVRIGVGTRPLQTRLVAP-ESTGGAEQDPVTVE TH_2597|M.thermoresistible__bu GPRMWERAPT--DPDFGRIRVGVAAQPLTPGLIPP-DLPPAEEADPVTVS MAB_3756c|M.abscessus_ATCC_199 GRRMWERRPG--DSDYCHVRVGTGDQRLAAQLVAP-EIGPVEELEPVASV Mflv_0327|M.gilvum_PYR-GCK TRRQWERDPH--DPDFLVLRAGLHDQPLDVTLRVK-DTADEIDLEPVSHT Mvan_0413|M.vanbaalenii_PYR-1 TRRQWERDPH--DPDFLVLRAGLHDQPLATALRVK-DTADEIDLEPVSHS Mb1812|M.bovis_AF2122/97 ALQEFGRYQSVVYNLPKMVSLLVEPWYALVGEREQVLGLMRAIICQLAFS Rv1784|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2665|M.marinum_M ALQEFGRYQSVVYNLPKMISLLVEPWYALVGEREQALGLMRAIICQLTFS MUL_3092|M.ulcerans_Agy99 ALQEFGRYQSVVYNLPKMISLLVEPWYALVGEREQALGLMRAIICQLTFS MAV_2932|M.avium_104 ALQEFGRYQSVVYNLPKMISLLVEPWYSLAGDREQVLGLMRAIICQLTFS MLBr_01543|M.leprae_Br4923 ALQEFGRYQSIVYNLPKMVSLLVEPWYALIGDREQTLGLMRSIICQLTFS MSMEG_1536|M.smegmatis_MC2_155 ALEALLRARSTVDDVPVTVRLGGHYRLTGPD--DQVAGLVRAVLCQLATW TH_2597|M.thermoresistible__bu AVQRLLRVRATVPDLPDTVAVFDHSAITVTG--DDAHGLARAMICQLAVL MAB_3756c|M.abscessus_ATCC_199 ALRRFVRTHSLVPELPIALNLRGFAAVTIDGSPEVARGMLRAMICQLAMF Mflv_0327|M.gilvum_PYR-GCK TLRGLLDAQRTLYDVPAGIALTRVSRITVLGDDAEVTGALRAWVAQAMTW Mvan_0413|M.vanbaalenii_PYR-1 TLRSLLDTQRTIHDAPAGVDLTKVARITVIGDRAEVAGALRAWIAQAVTW Mb1812|M.bovis_AF2122/97 HGPDHVQMIVVS--SDLDQWDWVKWLPHFGDSRRHDAAGNARMVYTSVRE Rv1784|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2665|M.marinum_M HGPDHVQFIVVS--SDLAEWEWVKWLPHFGDSRRYDAAGNARMVYSSVRE MUL_3092|M.ulcerans_Agy99 HGPDHVQFIVVS--SDLAEWEWVKWLPHFGDSRRYDAAGNARMVYSSVRE MAV_2932|M.avium_104 HGPDHVRMIVVS--SDLDEWDWVKWLPHFGDPRRQDAAGNARMVYSSVRE MLBr_01543|M.leprae_Br4923 HGPDHVQMVVVS--SDLEQWDWVKWLPHFGDPRRQDAAGNARMVYSSVRE MSMEG_1536|M.smegmatis_MC2_155 HSPRDVKIAAAPHADD--RWDWLKWLPHHTN------------------- TH_2597|M.thermoresistible__bu HGPDVLRIATVTTGDDG-VWDWLKWLPHHRHPWCTGHL------------ MAB_3756c|M.abscessus_ATCC_199 HGPDQFLVAAVVNRHAAPHWDWLKWLPHSQHPSAFDGVGTSRLVYHSLGE Mflv_0327|M.gilvum_PYR-GCK HDPSVLGIAFAGEALESEAWSWLKWLPHVDVPGRIDGVGPARYLAGDASD Mvan_0413|M.vanbaalenii_PYR-1 HDPSVLGVAFAGTRLESDAWSWLKWLPHTDVPGQNDGVGPARYLATEPAA Mb1812|M.bovis_AF2122/97 FAAEQAELFAGRGSFTPRHASSSAQTPTPHTVIIADVDDPQWEYVISAEG Rv1784|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2665|M.marinum_M FAAEQGELFAGRGSFTPRHASSSAQTPTPHTVIICDVDDPQWEYVISAEG MUL_3092|M.ulcerans_Agy99 FAAEQGELFAGRGSFTPRHASSSAQTPTPHTVIICDVDDPQWEYVISAEG MAV_2932|M.avium_104 FAAEQAELFAGRGSFTPRHASSSAQTPTPHTVIIADAVDPQWEYVISAEG MLBr_01543|M.leprae_Br4923 FATEQAELFAGRGSFTPRHASSSAQTPTPHHLIVADVVDPEWEYVISVEG MSMEG_1536|M.smegmatis_MC2_155 --------------------TPYDGA--AHLVIVAD-------SPVSDTL TH_2597|M.thermoresistible__bu -----------RHRDLTEIDRAADRA--RWLVIRDG-------HRGEDAA MAB_3756c|M.abscessus_ATCC_199 VEESLASLITERERFSRTAQPSPDRP--QILIVVDSGTLIGSERLIVDHG Mflv_0327|M.gilvum_PYR-GCK LRTLLAPALADRSGFTGDATGTTKHLLIVLDDPDAD------PSEFIGSG Mvan_0413|M.vanbaalenii_PYR-1 LHALLAPALAERAPFTGDGPTDAKHLLVVLDDPDAD------PGQFIGRG Mb1812|M.bovis_AF2122/97 VDGVTFFDLTGSSMWTDIPERKLQFDKTGVIEALPRDRDTWMVIDDKAWF Rv1784|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2665|M.marinum_M VDGVTFFDLTGSPMWTNVPERKLEFDKTGVIEALPRDRDTWMVIDDNAWF MUL_3092|M.ulcerans_Agy99 VDGVTFFDLTGSPMWTNVPERKLEFDKTGVIEALPRDRDTWVVIDDNAWF MAV_2932|M.avium_104 VDGVTFFDLTGSSMWSSVPERTLRFDDKGVIEALPRDRDTWMVIDEKPWF MLBr_01543|M.leprae_Br4923 IDGVTFFDLTGSSMWTVVPKRTLRFDEKGVIDALPRDRDTWMVIDDKPWF MSMEG_1536|M.smegmatis_MC2_155 PDGATVLGLGSDATDASATR----------IDVEHDEVRI-------ATV TH_2597|M.thermoresistible__bu PPGVTVLTVASAADSIRTDE----------LLLDTGDR------------ MAB_3756c|M.abscessus_ATCC_199 IDSVTLVEIGTRVDPLAARRG---------MQLELTERGLGAKGNVGSEV Mflv_0327|M.gilvum_PYR-GCK LAGVTVIHRSATEPDRDQYSDPER-----PVLRISGGRIERWQNGTWASN Mvan_0413|M.vanbaalenii_PYR-1 LAGVTVIHRTDREPDRDQYPDPER-----PVLRVAARRIERWLNGSWVPF Mb1812|M.bovis_AF2122/97 FALTDQVSIAEAEEFAQKLAQWRLAEAYEEIGQRVAHIGARDILSYYGID Rv1784|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2665|M.marinum_M FALTDHVSIAEAEEFGQKLAQWRLAEAYEEIGQRVAHIGARDILAYYGID MUL_3092|M.ulcerans_Agy99 FALTDHVSIAEAEEFGQKLAQWRLAEAYEEIGQRVAHIGARDILAYYGID MAV_2932|M.avium_104 FALTDHLSVAEAEEFAQKLARWRLAEAYEEIGQRVAHIGARDILSYYGIE MLBr_01543|M.leprae_Br4923 FALADQLSFAEAEEFAQKLAHWRPAEAYEEIGQRVAHIGARDILSYYGIG MSMEG_1536|M.smegmatis_MC2_155 SARPDTMTAEQALACARRLARYRAEAAS--------ARR-SDWANLLGVD TH_2597|M.thermoresistible__bu DRCTDSLSPVAALACARRLSAFRTAAVR--------NRSPWNWLELMDVD MAB_3756c|M.abscessus_ATCC_199 FAHPDHLTITEAMACARRLAPYRVLTGSGDE-VQIQTEVSTRWSDIVGIG Mflv_0327|M.gilvum_PYR-GCK IDSADHLGAADARHIARRLARWDSNPDHARS----ATTGGAAFTTLLGIP Mvan_0413|M.vanbaalenii_PYR-1 VDAADRMAPDDARHIARRLARWDSNPHHGRS----ASAGGAAFTTLLGIP Mb1812|M.bovis_AF2122/97 DPGNIDFDSLWASRTDTMGRSRLRAPFGNRSDNGELLFLDMKSLDEGGDG Rv1784|M.tuberculosis_H37Rv -----------------MGRSRLRAPFGNRSDNGELLFLDMKSLDEGGDG MMAR_2665|M.marinum_M DPGNIDFDYLWGSRTDSMGRSRLRAPFGNRSDNGELLFLDMKSLDEGGDG MUL_3092|M.ulcerans_Agy99 DPGNIDFDYLWGSRTDSMGRSRLRAPFGNRSDNGELLFLDMKSLDEGGDG MAV_2932|M.avium_104 DPGNIDFDALWGGRTDTMGRSRLRAPFGVRSDNGELLFLDMKSLDEGGDG MLBr_01543|M.leprae_Br4923 DPSAIDFDALWNSRTDAMGKSRLRVPFGNRSDNGELLFLDMKSLDEGGDG MSMEG_1536|M.smegmatis_MC2_155 DITHLGIERVWQN---LDPRQRLR-VPIGISDHGVRVDLDLNEAARGGSG TH_2597|M.thermoresistible__bu DPELLPDTRWADT---GGAGAVLSPVPLGVSETGARLDLDINEAARGGMG MAB_3756c|M.abscessus_ATCC_199 DPGLLNPEVVWRN---RVGRDRLR-VPIGIAVDGTPMELDIKEAAENGMG Mflv_0327|M.gilvum_PYR-GCK DASALDVAALWAP----RNRDDELRVPIGVTATGEPLIFDLKDEAEGGMG Mvan_0413|M.vanbaalenii_PYR-1 DASALDVAALWAP----RNRDDELRVPIGVTATGEPLIFDLKDEAEGGMG : * : :*::. ..* * Mb1812|M.bovis_AF2122/97 PHGVMSGTTGSGKSTLVRTVIESLMLSHPPEELQFVLADLKGGSAVKPFA Rv1784|M.tuberculosis_H37Rv PHGVMSGTTGSGKSTLVRTVIESLMLSHPPEELQFVLADLKGGSAVKPFA MMAR_2665|M.marinum_M PHGVMSGTTGSGKSTLVRTVIESLMLGHPPEELQFVLADLKGGSAVKPFA MUL_3092|M.ulcerans_Agy99 PHGVMSGTTGSGKSTLVRTVIESLMLGHPPEELQFVLADLKGGSAVKPFA MAV_2932|M.avium_104 PHGVMSGTTGSGKSTLVRTVIESLMLSHPPEELQFVLADLKGGSAVKPFA MLBr_01543|M.leprae_Br4923 PHGVMSGTTGSGKSTLVRTVIESLMLAHPPEELQFVLADLKGGSAVKPFA MSMEG_1536|M.smegmatis_MC2_155 PHGLCIGATGSGKSEFLRTLVLGLITTHSPDALNLVLVDFKGGATFLGLA TH_2597|M.thermoresistible__bu PHGLCVGATGSGKSELLRTLVLGLITVHPPEVLNLILVDFKGGATFLGLE MAB_3756c|M.abscessus_ATCC_199 PHGLCIGATGSGKSEFLRTLTLGMIATHSPDALNLVLVDFKGGATFLGLD Mflv_0327|M.gilvum_PYR-GCK PHGLMIGMTGSGKSQTLMSILLSLLTTHPADRLIVIYADFKGEAGADIFR Mvan_0413|M.vanbaalenii_PYR-1 PHGLMIGMTGSGKSQTLMAILLSLLTTHPADRLIVIYADFKGEAGADIFR ***: * ****** : :: .:: *..: * .: .*:** : : Mb1812|M.bovis_AF2122/97 GVPHVSRIITDLEEDQALMERFLDALWGEIARRKAICDSAG---VDDAKE Rv1784|M.tuberculosis_H37Rv GVPHVSRIITDLEEDQALMERFLDALWGEIARRKAICDSAG---VDDAKE MMAR_2665|M.marinum_M GVPHVSRIITDLEEDQALMERFLDALWGEIARRKAICDSAG---VDDAKE MUL_3092|M.ulcerans_Agy99 GVPHVSRIITDLEEDQALMERFLDALWGEIARRKAICDSAG---VDDAKE MAV_2932|M.avium_104 GVPHVSRIITDLEEDQALMERFLDALWGEIARRKAICDSAG---VDDAKE MLBr_01543|M.leprae_Br4923 GVPHVSRIITDLEEDQVLMERFLDALWGEIARRKAVCDNAG---VDDAKE MSMEG_1536|M.smegmatis_MC2_155 SAPHISALITNLSDEAAMVARMADALAGEMTRRQELLRAA----NVGSAA TH_2597|M.thermoresistible__bu RANHVSAVITNLSDEAHLVARMYDALSGELNRRQELLRAAG---NAADLA MAB_3756c|M.abscessus_ATCC_199 RAQHVAAIITNLAEEANLVSRMKDALAGEMNRRQELLRAAG---NFANVT Mflv_0327|M.gilvum_PYR-GCK NFPQVVAVISNMAEKRSLADRFADTLRGEVARREQLLKDSGRRVQGSAFN Mvan_0413|M.vanbaalenii_PYR-1 NFPQVVAVISNMAEKRSLADRFADTLRGEVARREQLLLEAGRRIQNSAFN :: :*::: :. : *: *:* **: **: : : Mb1812|M.bovis_AF2122/97 YNSVRARMRARGQDMAPLPMLVVVIDEFYEWFRIMPTAVDVLDSIGRQGR Rv1784|M.tuberculosis_H37Rv YNSVRARMRARGQDMAPLPMLVVVIDEFYEWFRIMPTAVDVLDSIGRQGR MMAR_2665|M.marinum_M YNSVRGRMRARGQDMAPLPMLVVVIDEFYEWFRIMPTAVDVLDSIGRQGR MUL_3092|M.ulcerans_Agy99 YNSVRGRMRARGQDMAPLPMLVVVIDEFYEWFRIMPTAVDVLDSIGRQGR MAV_2932|M.avium_104 YNAVRARMRARGQDMPPLPMLVVVIDEFYEWFRIMPTAVDVLDSIGRQGR MLBr_01543|M.leprae_Br4923 YNSVRTRMRARGQDMPALPMLVVVIDEFYEWFRIVPTAVDVLDSIGRQGR MSMEG_1536|M.smegmatis_MC2_155 EYTR---TNGR----PPLPTLLVVVDEFSELLHQHPDFADLFVAIGRLGR TH_2597|M.thermoresistible__bu EYTA---ARATRPDLPLLPALLIAVDEFSELLAQHPEFAELFVAIGRLGR MAB_3756c|M.abscessus_ATCC_199 EYER---ARAAGASLSPLPALFIIVDEFSELLSQHPDFAELFVAIGRLGR Mflv_0327|M.gilvum_PYR-GCK SVTEYENAVREGHDLPPIPTLLVVADEFTLMLADHPEYADLFDYVARKGR Mvan_0413|M.vanbaalenii_PYR-1 SVTEYENAIAEGHDLPPLPTLFVVADEFTLMLAEHPEYADLFDYVARKGR . :* *.: *** : * .::: :.* ** Mb1812|M.bovis_AF2122/97 AYWIHLMMASQTIES-RAEKLMENMGYRLVLKARTAG-AAQAAGVPNAVN Rv1784|M.tuberculosis_H37Rv AYWIHLMMASQTIES-RAEKLMENMGYRLVLKARTAG-AAQAAGVPNAVN MMAR_2665|M.marinum_M AYWIHLMMASQTIES-RAEKLMENMGYRLVLKARTAG-AAQAAGVPNAVN MUL_3092|M.ulcerans_Agy99 AYWIHLMMASQTIES-RAEKLMENMGYRLVLKARTAG-AAQAAGVPNAVN MAV_2932|M.avium_104 AYWIHLMMASQTIES-RAEKLMENMGYRLVLKARTAG-AAQAAGVPNAVN MLBr_01543|M.leprae_Br4923 AYWIHLMMASQTIES-RAEKLMENMGYRLVLKARTAG-AAQAAGVPNAVN MSMEG_1536|M.smegmatis_MC2_155 SLGIHLLLASQRLDEGRLRGLESHLSYRICLKTFSAAESRAVLGVADAHD TH_2597|M.thermoresistible__bu SLGMHLLLSSQRVDEGRLRGLETHLSYRICLKTFSAGDSRAVLGVPDAYQ MAB_3756c|M.abscessus_ATCC_199 SLHVHLLLASQRLDEGRLRGLESHLSYRLCLKTFSANESRAAIGVPDAYH Mflv_0327|M.gilvum_PYR-GCK SFRIHLLFASQTLDVGRIKDIDKNTSYRIGLKVASPSVSRQIIGVEDAYH Mvan_0413|M.vanbaalenii_PYR-1 SFRIHLLFASQTLDVGRIKDIDKNTSYRIGLKVASPAVSRQIIGVEDAYH : :**:::** :: * . : : .**: **. :. : ** :* . Mb1812|M.bovis_AF2122/97 LP---AQAGLGYFRKSL-EDIIRFQAEFLWRDYFQPGVSIDGEEAPALVH Rv1784|M.tuberculosis_H37Rv LP---AQAGLGYFRKSL-EDIIRFQAEFLWRDYFQPGVSIDGEEAPALVH MMAR_2665|M.marinum_M LP---AQAGLGYFRKSL-EDIIRFQAEFLWRDYFQPGITVDGEEAPVLVH MUL_3092|M.ulcerans_Agy99 LP---AQAGLGYFRKSL-EDIIRFQAEFLWRDYFQPGITVDGEEAPVLVH MAV_2932|M.avium_104 LP---AQAGLGYFRRSL-EDIVRFQAEFLWRDYFPRGISDDGEEAPALVH MLBr_01543|M.leprae_Br4923 LP---AQAGLGYFRKSL-EDVIRFQAEFLWRDYFR-GVTLDGEEQPVLVH MSMEG_1536|M.smegmatis_MC2_155 LP---NTPGAAYLKTPS-GEITRFQTAFVSG---------RYDVAPVDRS TH_2597|M.thermoresistible__bu LP---ARPGAALLKTVS-DELVRFQTAYVSGPLL------RTREKPAEPD MAB_3756c|M.abscessus_ATCC_199 LP---NTPGSCYLKDDS-GELTRFQTSYVSGPYVPYGPARRTVSSGGGGA Mflv_0327|M.gilvum_PYR-GCK IESGREHKGVGFLVPAPGALPVKFRSTYVDGIYEP----PRVDRSIVVHA Mvan_0413|M.vanbaalenii_PYR-1 IESGREHKGEGFLVPAPGALPIKFRSTYVDGIYEP----PRVDRSIVVHA : * : :*:: :: Mb1812|M.bovis_AF2122/97 SIDYIRPQLFTNSFTPLEVSVGGPDIEPVVAQPNGEMLESDDIEGGEDED Rv1784|M.tuberculosis_H37Rv SIDYIRPQLFTNSFTPLEVSVGGPDIEPVVAQPNGEVLESDDIEGGEDED MMAR_2665|M.marinum_M SIDYIRPQLFTNSFTPLEVTVGGPEIDKVVAHANGEVVE--EVEAEAE-- MUL_3092|M.ulcerans_Agy99 SIDYIRPQLFTNSFTPLEVTVGGPEIDKVVAHANGEVVE--EAEAEAEAE MAV_2932|M.avium_104 SIDYVRPQLFTNSFTPLEVSVGGPDVTVPAIPAAGADMP--EIEGPDDDD MLBr_01543|M.leprae_Br4923 NIDYVRPQLFTNLFTPLEVSVGGPEVDAEAVFANAQEFD---EEIAEEEA MSMEG_1536|M.smegmatis_MC2_155 DHRVR----------PFTARP------------------------PADQL TH_2597|M.thermoresistible__bu APRVFT---------PEPAAA------------------------SADRM MAB_3756c|M.abscessus_ATCC_199 APRLFTAAPVALQMRPAEVVE------------------------DDSPA Mflv_0327|M.gilvum_PYR-GCK IPKPQLFSAGWVDPEPDTVIV------------------------DDGAD Mvan_0413|M.vanbaalenii_PYR-1 IPKPQLFSAGWVDPEPDTVIV------------------------DDGAD * . Mb1812|M.bovis_AF2122/97 EEGVRTPKVGTVIIDQLRKIKFEPYRLWQPPLTQPVAIDDLVNRFLGRPW Rv1784|M.tuberculosis_H37Rv EEGVRTPKVGTVIIDQLRKIKFEPYRLWQPPLTQPVAIDDLVNRFLGRPW MMAR_2665|M.marinum_M EEGIRVPKVGTVIIDQLRRINFEPYRLWQPPLTQPVAIDDLVNRFLGHPW MUL_3092|M.ulcerans_Agy99 EEGIRVPKVGTVIIDQLRRINFEPYRLWQPPLTQPVAIDDLVNWFLGHPW MAV_2932|M.avium_104 VEGIRTPKVGTVIIDQLRKIDFQPYRLWQPPLDQPIAIDELVNRFLGHPW MLBr_01543|M.leprae_Br4923 EGGVRTPKIGTVIIDQLRRIDFEPYRLWQPPLTQPVAIDDLVNRFLGHPW MSMEG_1536|M.smegmatis_MC2_155 CR-SSTQTTLEATVARLLGHGTPAHRVWLSPLPRAIPLSDVLM------- TH_2597|M.thermoresistible__bu RSDGPVRTLLDTVVDRLAGHGTAAHRVWLEPLSASPPLGALLS------- MAB_3756c|M.abscessus_ATCC_199 VSEATGRSVIDTILDRVEGHGNPAHEVWLPPLDDSPTLGDLIPRHG---- Mflv_0327|M.gilvum_PYR-GCK VEVLPPRKLIATIGEQLVHYGPRAPQLWLPPLEEAIPLQGLLERSG---- Mvan_0413|M.vanbaalenii_PYR-1 VEVLPPRKLITTIGEQLAQYGPRAPQLWLPPLDEPIPLRDVLERAG---- . . :: . .:* ** . .: :: Mb1812|M.bovis_AF2122/97 HKEYGSACNLVFPIGIIDRPYKHDQPPWTVDTSGPGANVLILGAGGSGKT Rv1784|M.tuberculosis_H37Rv HKEYGSACNLVFPIGIIDRPYKHDQPPWTVDTSGPGANVLILGAGGSGKT MMAR_2665|M.marinum_M QKEYGSARNLVFPIGVIDRPFKHDQPPWTVDTSGPGSNVLILGAGGSGKT MUL_3092|M.ulcerans_Agy99 QKEYGSARNLVFPIGVIDRPFKHDQPPWTVDTSGPGSNVLILGAGGSGKT MAV_2932|M.avium_104 QQDYGTARDLVFPIGIIDRPFKHDQPPWTVDTSGPGANVLILGAGGSGKT MLBr_01543|M.leprae_Br4923 QKDYGSARNLVFPIGVIDRPFKHDQPAWTVDTSGPGSNVLVLGAGGSGKT MSMEG_1536|M.smegmatis_MC2_155 ---ADP-EPLTAAIGLVDRPFEQRRDRLLVDLSGAAGNVVIVGGPQSGKS TH_2597|M.thermoresistible__bu ---ARHGAPLTVPIGVVDCPFEQRRIPLVAALAGADGNVAVVGGPQSGKS MAB_3756c|M.abscessus_ATCC_199 RAGFDAVGSLTVPIGIVDRPYEQRRDPYIVDLSAAAGNVAIVGAPQSGKS Mflv_0327|M.gilvum_PYR-GCK ----IGAGQWRWPLGEIDRPFDMRRDPLVFDATSAAANMVIHGGPKSGKS Mvan_0413|M.vanbaalenii_PYR-1 ----VGARQWRWPLGEIDRPFEMRRDPLIFDATSAAANMVIHGGPKSGKS .:* :* *:. : :.. .*: : *. ***: Mb1812|M.bovis_AF2122/97 TALQTLICSAALTHTPQQVQFYCLAYSSTALTTVSRIPHVGEVAGPTDPY Rv1784|M.tuberculosis_H37Rv TALQTLICSAALTHTPQQVQFYCLAYSSTALTTVSRIPHVGEVAGPTDPY MMAR_2665|M.marinum_M TALQTLISSAALTHTPDQVQFYCLAYSSTALTTVSKLPHVGEVAGPTDPY MUL_3092|M.ulcerans_Agy99 TALQTLISSAALTHTPDQVQVYCLAYSSTALTTVSKLPHVGEVAGPTDPY MAV_2932|M.avium_104 TALQTLICSAALTHTPEQVQFYCLAYSSTALTTVARLPHVGEVVGPTDPY MLBr_01543|M.leprae_Br4923 TALQTIICSAALTHTPEQVQFYCLGYSGTALTTVAHLPHVGEVAGPTDPY MSMEG_1536|M.smegmatis_MC2_155 TAARTLMVALSATHDPADVQMYGLDLGGGALCALTALPHVGAVAGRRDTD TH_2597|M.thermoresistible__bu TVVRTLVMALAATHDPRDVQVYCVDCGGGALTALSALPHVGAVAGRGDAE MAB_3756c|M.abscessus_ATCC_199 MAVRTLVTSLAVTHSPAQVQFYCLDFGGGTLTSLAQLPHVGSVASRLESD Mflv_0327|M.gilvum_PYR-GCK TALQTFVLSAAALHAPGDVSFYCLDYGGGQLRVLDGLAHVGSVASPLESE Mvan_0413|M.vanbaalenii_PYR-1 SALQTFVLSAAALHAPGDVSFYCLDYGGGQLRALENLAHVGSVASPLEPE . :*:: : : * * :*..* : .. * : :.*** *.. :. Mb1812|M.bovis_AF2122/97 GVRRTVAELLALVRERKRSFLECGIASMEMFRRRKFGGEAGPVPDDGFGD Rv1784|M.tuberculosis_H37Rv GVRRTVAELLALVRERKRSFLECGIASMEMFRRRKFGGEAGPVPDDGFGD MMAR_2665|M.marinum_M GVRRTVAELLALVRERKRSFLEYGIASMEMFRRRKFGGEAGPVPNDGFGD MUL_3092|M.ulcerans_Agy99 GVRRTVAELLALVRERKRSFLEYGIASMEMFRRRKFGGEAGPVPNDGFGD MAV_2932|M.avium_104 GVRRTVAELLALVRERKRSFLEYGIPSMEVFRRRKFGGEPGPVPNDGFGD MLBr_01543|M.leprae_Br4923 GVRRTVAELLALVRDRKRSFLEHGIASMEVFRRRKFGGELGPVPNDGFGD MSMEG_1536|M.smegmatis_MC2_155 LARRIVTQLHDVIRARERTFEVLGVDSMADYRARRAAGE---CRDDPYGD TH_2597|M.thermoresistible__bu LISRIVAVLEKILADRETRFRAAGVDSMAERRRRRQ-------RDDPYGD MAB_3756c|M.abscessus_ATCC_199 LIRRTFAEMLTIVRSRENAFRAYGIDSMAEYRRRKGAGDP-QLANDPFGD Mflv_0327|M.gilvum_PYR-GCK RIRRTFGELEQLLQARQRHGAAVNNGGYR----------------DGYGE Mvan_0413|M.vanbaalenii_PYR-1 RIRRTFGELEHLLRARQQHGAAAADGQYR----------------DGYGE * . : :: *: * :*: Mb1812|M.bovis_AF2122/97 VYLVIDNYRALAEE-------NEVLIEQVNVIINQGPSFGVHVVVTADRE Rv1784|M.tuberculosis_H37Rv VYLVIDNYRALAEE-------NEVLIEQVNVIINQGPSFGVHVVVTADRE MMAR_2665|M.marinum_M VYLVIDNYRALAEE-------NEVLIEQVNLIINQGPSFGVHVVVTADRE MUL_3092|M.ulcerans_Agy99 VYLVIDNYRALAEE-------NEVLIEQVNLIINQGPSFGVHVVVTADRE MAV_2932|M.avium_104 VYLVVDNYRALAEE-------NEVLIEQVNVIINQGPSFGVHVVVTADRE MLBr_01543|M.leprae_Br4923 VYLVIDNYRALVEE-------NEVLIEQVNQIINQGPSFGVHVVVTADRE MSMEG_1536|M.smegmatis_MC2_155 VFLVVDGWSTLRTE-------FESLESTITTLAGQGLSYGVHVVVTAARW TH_2597|M.thermoresistible__bu VFLVIDGIAVIRNE-------FDTIEPRIAALAAQGLGYGVHVVVTASRW MAB_3756c|M.abscessus_ATCC_199 VFFIIDGWSTVRQE-------FEALEPQVTALAAQGLGFGVHTVVTASRW Mflv_0327|M.gilvum_PYR-GCK VFLLIDNLYAFSRDNTDTFNTRNPLLAKVTELVNTGLAYGIHVVITTPNW Mvan_0413|M.vanbaalenii_PYR-1 VFLLIDNLYAFSRDNTDTFNARNPLLARVTELVNTGLSYGIHVVVTTPNW *::::*. .. : : : : : * .:*:*.*:*: . Mb1812|M.bovis_AF2122/97 SELRPPVRSGFGSRIELRLAAVEDAKLVRSRFAKDVPVKPGRGMVAVNYV Rv1784|M.tuberculosis_H37Rv SELRPPVRSGFGSRIELRLAAVEDAKLVRSRFAKDVPVKPGRGMVAVNYV MMAR_2665|M.marinum_M SELRPPVRSGFGSRVELRLAAVEDAKLVRSRFAKDVPVKPGRGMVAVNYV MUL_3092|M.ulcerans_Agy99 SELRPPVRSGFGSRVELRLAAVEDAKLVRSRFAKDVPVKPGRGMVAVNYV MAV_2932|M.avium_104 SELRPPVRSGFGSRVELRLAAVEDAKLVRSRFAKDVPVKPGRGMVAVNYV MLBr_01543|M.leprae_Br4923 SELRPQVRSGFGSRVELRLAAVEDAKLVRSRFAKDVPVQSGRGMVAVNYV MSMEG_1536|M.smegmatis_MC2_155 AELRPALKDQLGTRIELRLGDPAESEMDRRRARHIS-PLPGRGLTRDGHE TH_2597|M.thermoresistible__bu AELRPVLKDQLGTRIELRLGDPADSEMDRRRARHLIDSPPGRGITRDGRE MAB_3756c|M.abscessus_ATCC_199 AEIRPALKDQIGTRVELRLGDPLDSDFDRKLAQLVPDGRPGRGITRDRRH Mflv_0327|M.gilvum_PYR-GCK LEVPLAMRDGLGLRLELRLHDAHDSNVR-VVG---ALRRPAEGVPADQPG Mvan_0413|M.vanbaalenii_PYR-1 LEVPLTMRDGLGLRLELRLHDPRDSNVR-VVSKDAALRRPAESVPADQPG *: ::. :* *:**** ::.. ....: Mb1812|M.bovis_AF2122/97 RLDSDPQAGLHTLVARPALGSTPDNVFECDSVVAAVSRLTSAQAPPVRRL Rv1784|M.tuberculosis_H37Rv RLDSDPQAGLHTLVARPALGSTPDNVFECDSVVAAVSRLTSAQAPPVRRL MMAR_2665|M.marinum_M RLDSDPQAGLHTLVARPAMGSTPTNVFECDSVVAAVSRLTTSQAPPVRRL MUL_3092|M.ulcerans_Agy99 RLDSDPQAGLHTLVARPAMGSTPTNVFECDSVVAAVSRLTTSQAPPVRRL MAV_2932|M.avium_104 RLDADPQSGLHTLVARPALASTPDNRFESDSVVEAVSRLATGQAPPVRRL MLBr_01543|M.leprae_Br4923 RLDSDPQAGLHTLVARPALANTPANVFESDSVVAPVSRLTSAQAPPVRRL MSMEG_1536|M.smegmatis_MC2_155 LLIALPR-------LDGTADERGLAAALTRVGEVLHTQHTGAHAPRVRLL TH_2597|M.thermoresistible__bu LTIALPR-------LDEAASTTGLAASIAASAQALHIRYQQRTAPPVELL MAB_3756c|M.abscessus_ATCC_199 MLIGLPR-------VDSISSNQDLGEAIAAAAASMRQRSS-VEAPQVRML Mflv_0327|M.gilvum_PYR-GCK RG------------LTMAAEHFLFARPAPETIPALNARFPGQSAPEVRLL Mvan_0413|M.vanbaalenii_PYR-1 RG------------LTMAVEHFLFAAPATESIPALNARYPGRSAPPVRLL : ** *. * Mb1812|M.bovis_AF2122/97 PARFGVEQVRELASRDTRQGVGAGGIAWAISELDLAPVYLNFAENSHLMV Rv1784|M.tuberculosis_H37Rv PARFGVEQVRELASRDTRQGVGAGGIAWAISELDLAPVYLNFAENSHLMV MMAR_2665|M.marinum_M PASFGVDQVRQLAARDTRQGVGVGGIAWAISELDLQPVYLNFAENSHLMV MUL_3092|M.ulcerans_Agy99 PASFGVDQVRQLAARDTRQGVGVGGIAWAISELDLQPVYLNFAENSHLMV MAV_2932|M.avium_104 PATFGLDQLRELAAQDTRQGVGAGGIAWAISELDLSPVYLNFDENAHLMV MLBr_01543|M.leprae_Br4923 PARFGMEQVRERAVRDTRQGVGVGGIAWAISELDLQPVYLNFAENAHLMI MSMEG_1536|M.smegmatis_MC2_155 PRHVAGDDLVGLR--GDRPAT---QVVLGIGDAELAPVAVDFAEQSDLVI TH_2597|M.thermoresistible__bu PGRVDHETVLAAA--SEVQRA---RTILGLGETDLEPVTLDLTEQPHLVM MAB_3756c|M.abscessus_ATCC_199 PHKIDYAALVPQAPQNDQPNL---RILVGINESELAPTFLEFGEQPHMMI Mflv_0327|M.gilvum_PYR-GCK PTRLSPRAFASLYPAPER-------VVIGQREEDLAAVSVDFADNPLLMV Mvan_0413|M.vanbaalenii_PYR-1 PTDLSPSAFPTLYPAPER-------VVVGQREEDLAAVTVDFGDNPLMMV * . . . : :* .. ::: ::. ::: Mb1812|M.bovis_AF2122/97 TGRRECGRTTTLATIMSEIGRLYAPGASSAPPPAPGRPSAQVWLVDPRRQ Rv1784|M.tuberculosis_H37Rv TGRRECGRTTTLATIMSEIGRLYAPGASSAPPPAPGRPSAQVWLVDPRRQ MMAR_2665|M.marinum_M TGRRECGRTTTLATIMSEIGRLYAPGATSVPAPPPGQPSAQVWLIDPRRQ MUL_3092|M.ulcerans_Agy99 TGRRECGRTTTLATIMSEIGRLYAPGATSVPAPPPGQPSAQVWLIDPRRQ MAV_2932|M.avium_104 TGRRECGRTTTLATIMKEIGRLYAPGASSAPTPPAGQPSAQVWLVDPRRQ MLBr_01543|M.leprae_Br4923 TGRRECGRTTVLATIMSEIGRLYAPGGTSAPPTS--ERSAQVWLIDPRRQ MSMEG_1536|M.smegmatis_MC2_155 LGDAGCGKSTALRALCDRLVRTNDP------------SAVQLLVVDYRRE TH_2597|M.thermoresistible__bu LGDPRSGKTAALRTVCREILRTHSP------------TAAQLLLVDFRRT MAB_3756c|M.abscessus_ATCC_199 FGDSECGKTALLRTMCREIVRTTTP------------QQAQLFIVDYRRT Mflv_0327|M.gilvum_PYR-GCK FGDTKTGKTTLLRHLIRTLRENSRA-------------DQVAFTVIDRRL Mvan_0413|M.vanbaalenii_PYR-1 FGDAKTGKTTLLRHLIRTIRENSRP-------------DQVAFTVIDRRL * *::: * : : . . : ** Mb1812|M.bovis_AF2122/97 LLTALGSDYVERFAYNLDGVVAMMGELAAALAGREPPPGLSAEELLSRSW Rv1784|M.tuberculosis_H37Rv LLTALGSDYVERFAYNLDGVVAMMGELAAALAGREPPPGLSAEELLSRSW MMAR_2665|M.marinum_M LLTALGSNYVERFAYNLDGVQAMMGELAAVLAGREPPPGLSAEELLSRSW MUL_3092|M.ulcerans_Agy99 LLTALGSNYVERFAYNLDGVQAKMGELAAVLAGREPPPGLSAEELLSRSW MAV_2932|M.avium_104 LLTTLGSDYVEKFAYNLDGVQAMMGELAAALAGREPPPGLSAEELLSRNW MLBr_01543|M.leprae_Br4923 LLTMLGSNYMEKFAYNLDGVSAMVGELAALLASREPPPDLSAEELLSRSW MSMEG_1536|M.smegmatis_MC2_155 MLDAVGSDHLRGYAVSAGALETAVADLIRTLRERMPGPDIAPRQLRERTW TH_2597|M.thermoresistible__bu LLGVVETEHLGAYAMSPPTLQTALAGLVDRLRARLPDAAVTQRQLRDRSW MAB_3756c|M.abscessus_ATCC_199 LLGVVETEHLAKYAMSSNTLVDEVPALIELLKSRMPGPDVTQQELRDRSW Mflv_0327|M.gilvum_PYR-GCK QLVDEPIFPDNEYTPNIDRILPAMLGLAGLLEKRRPPAGLSPQELRGWDF Mvan_0413|M.vanbaalenii_PYR-1 QLVDEPIFPDNEYTPNIDRITPAMLGLSALLEKRRPPAGLSPQELSRWDF * :: . : : * * * * . :: .:* : Mb1812|M.bovis_AF2122/97 WSGPE------IFLIVDDIQQLPPG--------FDSPLHKAVPFVNRAAD Rv1784|M.tuberculosis_H37Rv WSGPE------IFLIVDDIQQLPPG--------FDSPLHKAVPFVNRAAD MMAR_2665|M.marinum_M WSGPE------IFLIVDDIQQLPPG--------FDSPLHKAAPWVNRAAD MUL_3092|M.ulcerans_Agy99 WSGPE------IFLIVDDIQQLPPG--------FDSPLHKAAPWVNRAAD MAV_2932|M.avium_104 WSGPE------IFLIVDDIQQLPAG--------FDSPLHKAAPWVTRAAD MLBr_01543|M.leprae_Br4923 WSGPE------IFLIIDDIQQLPPS--------FDSPLQKVVPWVTRAGD MSMEG_1536|M.smegmatis_MC2_155 WTGPE------LYVVVDDYDLVAAG--------AGNPLTSLLDFVPHARD TH_2597|M.thermoresistible__bu WTGPE------LFLVIDDYDLVAES--------AAAALTPVTELLPHGRD MAB_3756c|M.abscessus_ATCC_199 WSGPE------IYILVDDYDLVALA--------SGNPLLPLAEYLPHSKD Mflv_0327|M.gilvum_PYR-GCK RSSANGSGSHLHYLIIDDVDQIPDGPAVSGPYAGQRPWTPVIGLLSQASE Mvan_0413|M.vanbaalenii_PYR-1 RAGANGSGRHLHYLIIDDVDQIPDGPAISGPFAGQRPWTALIGLLAQASD :..: ::::** : :. . . : :. : Mb1812|M.bovis_AF2122/97 VGLHVIVTRTFGGWSSAGS-DPMLRALHQANAPLLVMDADPDEGFIRGKM Rv1784|M.tuberculosis_H37Rv VGLHVIVTRTFGGWSSAGS-DPMLRALHQANAPLLVMDADPDEGFIRGKM MMAR_2665|M.marinum_M VGLHVIVTRSFGGWSSAGS-DPMLRALHQANAPLLVMDADPDEGFIRGKM MUL_3092|M.ulcerans_Agy99 VGLHVIVTRSFGGWSSAGS-DPMLRALHQANAPLLVMDADPDEGFIRGKM MAV_2932|M.avium_104 VGLHVIVTRTFGGWSSAGS-DPMLRALAQANAPLLVMDADPDEGFIRGKM MLBr_01543|M.leprae_Br4923 VGLHVIATRTFGGWSSAGS-DPMLRALHQANAPLLVMDADPDEGFIRGKM MSMEG_1536|M.smegmatis_MC2_155 LGLHLVIARRSGGAARAMF-DPVLSRLKELGCMGLMMSASPDEGVLLGSV TH_2597|M.thermoresistible__bu IGLHVIVARRAGGAARAMF-DPLPARLRETGAAGLMLSAPPEEGQLWGSV MAB_3756c|M.abscessus_ATCC_199 IGLHVVIARRTSGASRAMF-EPMMARMKDLSCIGLQMSGNKDEGVLLGTV Mflv_0327|M.gilvum_PYR-GCK LGLRVIVTARAAGSAHAVMTAPLLRRLNELQATTLLLSGNPQDSGKIRGH Mvan_0413|M.vanbaalenii_PYR-1 LGLRVIVTARAAGSAHAVMTAPLLRRLNDLQATTFLLSGNPADSGKIRGH :**::: : .* : * *: : : . : :.. :. Mb1812|M.bovis_AF2122/97 KGGPLPRGRGLLMAEDTG----VFVQVAATEVRR------------- Rv1784|M.tuberculosis_H37Rv KGGPLPRGRGLLMAEDTG----VFVQVAATEVRR------------- MMAR_2665|M.marinum_M KGGPLPRGRGLLMAEDTG----VFVQVALTEVRK------------- MUL_3092|M.ulcerans_Agy99 KGGPLPRGRGLLMAEDTG----VFVQVALTEVRK------------- MAV_2932|M.avium_104 KGGPLPRGRGLLMAEDTG----VFVQVAATEFRK------------- MLBr_01543|M.leprae_Br4923 KGGPLPRGRGLLMAEDTG----VLVQVAETDMRR------------- MSMEG_1536|M.smegmatis_MC2_155 RPRPLPPGRGTLLTRSGPE---QLIQVALPCDVS------------- TH_2597|M.thermoresistible__bu RATPLPPGRATLLTRGRPA---QLIQVSWIEPP-------------- MAB_3756c|M.abscessus_ATCC_199 RPSEQPPGRGTLVMRSGGQ---QLIQVAWSEPQ-------------- Mflv_0327|M.gilvum_PYR-GCK RFSRLPAGRGLLLDDSNLSDTPTYVQLVDPLADDATAPAGHLGKEYS Mvan_0413|M.vanbaalenii_PYR-1 RFARLPVGRAMLLDDRNSSGSPTFVQLVNPLAERTAARSGHSGKEYS : * **. *: :*: