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LTTTVDGLWVLQAVTGVEQTCPELGLRPLLPRLDTAERALRHPVAAELMAVGALDQAGNADPMVREWLTV LLRRDLGLLVTIGVPGGEPTRAAICRFATWWVVLERHGNLVRLYPAGTASDEAGAGELVVGQVERLCGVA EAAPLRPVTVDADELLHAVRDAGTLRSYLLSQRLDVDQLQMVTMAADPTRSAHATLVALQAGVGPEKSAR ILVGDSTVAIVDTAAGRICVESVTSGQRRYQVLSPGSRSDIGGAVQRLIRRLPAGDEWYSYRRVV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3889c | - | - | 100% (276) | hypothetical protein Rv3889c |
| M. tuberculosis H37Rv | Rv3866 | - | 7e-09 | 26.14% (264) | hypothetical protein Rv3866 |
| M. tuberculosis H37Rv | Rv1794 | - | 5e-07 | 23.70% (308) | hypothetical protein Rv1794 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3918c | - | 1e-34 | 100.00% (68) | hypothetical protein Mb3918c |
| M. gilvum PYR-GCK | Mflv_0322 | - | 3e-05 | 25.22% (230) | putative DNA-binding protein |
| M. leprae Br4923 | MLBr_01540 | - | 7e-08 | 23.78% (307) | hypothetical protein MLBr_01540 |
| M. abscessus ATCC 19977 | MAB_2227c | - | 7e-07 | 27.78% (288) | hypothetical protein MAB_2227c |
| M. marinum M | MMAR_5441 | - | 1e-08 | 25.76% (264) | hypothetical protein MMAR_5441 |
| M. avium 104 | MAV_0155 | - | 1e-129 | 80.07% (276) | hypothetical protein MAV_0155 |
| M. smegmatis MC2 155 | MSMEG_0622 | - | 5e-09 | 27.11% (273) | putative DNA-binding protein |
| M. thermoresistible (build 8) | TH_2270 | - | 8e-10 | 25.56% (270) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3081 | - | 2e-06 | 22.80% (307) | hypothetical protein MUL_3081 |
| M. vanbaalenii PYR-1 | Mvan_0419 | - | 5e-07 | 25.65% (269) | putative DNA-binding protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0322|M.gilvum_PYR-GCK --------------MRANAVELSAASAWFLAEELGAGSYPWVLAITPPYS
Mvan_0419|M.vanbaalenii_PYR-1 --------------MHADAVELTAEAAWFLADTLGAGTFPWVLAITPPYS
MSMEG_0622|M.smegmatis_MC2_155 --------------MGPNAVELTTDQAWCLADVLGAGSYPWVLAITPPYS
MAB_2227c|M.abscessus_ATCC_199 ---------MDQANRSPDAVELTVDQAWFLADTLSAGTFPWVLAVTVPFR
Rv3889c|M.tuberculosis_H37Rv ------------------MLTTTVDGLWVLQAVTGVEQTCPELGLRPLLP
Mb3918c|M.bovis_AF2122/97 ------------------MLTTTVDGLWVLQAVTGVEQTCPELGLRPLLP
MAV_0155|M.avium_104 ------------------MLTTTVDGLWVLQAVTGIEQTCPELGLRPLLP
MMAR_5441|M.marinum_M MTGPLATG-RAGTGDDVVGVEVTIDGMLVIADRLHLVDFPVTLGIRPNIP
TH_2270|M.thermoresistible__bu MSVPQSLNPNASHIDDVVGVEVTIDGILVIADRLHLTDFPPALGIRPNIP
MLBr_01540|M.leprae_Br4923 ----------MDHQSTRTDITVNVDGFWLLQALLDIRHVAPELRCRPFVS
MUL_3081|M.ulcerans_Agy99 ----------MDQQSTRTDITVNVDGFWMLQALLDIRHVAPELRCRPYVS
: . : *
Mflv_0322|M.gilvum_PYR-GCK DVSARG-PFEREQTEKLRGAGIMTAERTVDPAVARWIRRVCRPTQWLELR
Mvan_0419|M.vanbaalenii_PYR-1 DRSQRA-QFESEQAERLTRMGVMDADRAVDAAVARWIRLVCRPTQWLELR
MSMEG_0622|M.smegmatis_MC2_155 DHSQRS-AFLAAQSAELTRMGVVNSAGAVDPRVAQWITTVCRATQWLDLR
MAB_2227c|M.abscessus_ATCC_199 DEAQRA-GFNAQRVQELTRAGILEPDGTVDPAVAGWIRTVCRPDRWLELR
Rv3889c|M.tuberculosis_H37Rv RLDTAERALRHPVAAELMAVGALDQAGNADPMVREWLTVLLRRD--LGLL
Mb3918c|M.bovis_AF2122/97 RLDTAERALRHPVAAELMAVGALDQAGNADPMVREWR--LMR--------
MAV_0155|M.avium_104 RLDTPERALRHPAAAELVAAGALDEAGNVDPMIREWLTVLLRRD--LGLL
MMAR_5441|M.marinum_M QEDLREIVWDQ-VARDLTAQGVLDHNGQPHPAVAAMVDTLSRADRTLEGR
TH_2270|M.thermoresistible__bu QEDIRERVWAQ-VARDLAAQEVLDAHGRPHPEVAAMVDALSRPDRTLDGR
MLBr_01540|M.leprae_Br4923 -TDSNDWLHEHPGMAVMREQGIVVN-GNVNEHVATRMRVFAAPDLEVVAL
MUL_3081|M.ulcerans_Agy99 -TDSNDWLNEHPGMAVMREQGIVVG-DTLNEQVAARMRVLAAPDLEVVAL
: : . : .
Mflv_0322|M.gilvum_PYR-GCK FVG----------------SRG---AVLRGVLARDG----AGTVIALRSG
Mvan_0419|M.vanbaalenii_PYR-1 FVG----------------ARG---AMLRGIIARDA----SRTVVALRSG
MSMEG_0622|M.smegmatis_MC2_155 FVS----------------GPG---DLLRGMVARRS----EETVVALRNA
MAB_2227c|M.abscessus_ATCC_199 YVA----------------AGSENPDVMRGIIARKQSQGRAQTVVSLRNA
Rv3889c|M.tuberculosis_H37Rv VTI----------------GVPGG-EPTRAAICRFA----TWWVVLERHG
Mb3918c|M.bovis_AF2122/97 --------------------------------------------------
MAV_0155|M.avium_104 VMI----------------AVPGR-EPSRASICRFA----TWWVVLERHD
MMAR_5441|M.marinum_M WWR----------------RDVGG-VMVRFVVCRKG----ERHVIAVRDG
TH_2270|M.thermoresistible__bu WWR----------------RDVGE-KMIRFVVCRKG----DRHVIAARDG
MLBr_01540|M.leprae_Br4923 LSRGKLLYGAVNDENQPPGSRDIPENEFRVVLVRRG----SHWASAVRVG
MUL_3081|M.ulcerans_Agy99 LSRGKLLYGVVDNEDQPPGSRDIPDNEFRVVLARRG----QHWVSAVRVG
Mflv_0322|M.gilvum_PYR-GCK GLITLTELDIDHPEALVPVVTAGLS---GRAPARFDGFSLPARVGAKADE
Mvan_0419|M.vanbaalenii_PYR-1 GLITLTEMQIDHPQALVPVLTVGLS---GRSPARFPEFSLPARVGAKADD
MSMEG_0622|M.smegmatis_MC2_155 QLVTFTAMDIGHQHALVPVLTAGLS---GRKPARFDDFALPAAAGARADE
MAB_2227c|M.abscessus_ATCC_199 HLITFTVVDADDSSALVPSVVAGLR---WRAPARFPEFTLPTNVGAKADE
Rv3889c|M.tuberculosis_H37Rv NLVRLYPAGTASDEAGAGELVVGQV---ERLCGVAEAAPLRP-VTVDADE
Mb3918c|M.bovis_AF2122/97 --------------------------------------------------
MAV_0155|M.avium_104 QLVRLYPAGTASSEAAASEIVVGQI---ERLCGVAEAAPLRP-ITLDTEQ
MMAR_5441|M.marinum_M DMLVLQLVAPRVG-------LAGMV---TAVLGTAEPANVEP-LTG-IAS
TH_2270|M.thermoresistible__bu DLLVLQRIAPQVG-------LAGMV---TAMLGPAAPADVEP-LTG-LAS
MLBr_01540|M.leprae_Br4923 NDITIDDVAIADSASITSLVMDGLESIHHADPAAINAVNVPLEEMLEATK
MUL_3081|M.ulcerans_Agy99 NDITVDDVSVSDSASIAALVIDGLESIHHADPAAINAVNVPLEEMLEATK
Mflv_0322|M.gilvum_PYR-GCK QIRKG----AAVGGLLDYLGIPPSARPVVVAAFEDSRT----YVEIVAGQ
Mvan_0419|M.vanbaalenii_PYR-1 QIRRG----ASVRDLLDYLGVPPSARPVVVAAFEEART----YVEIVAGR
MSMEG_0622|M.smegmatis_MC2_155 QIRNG----APLAEVLEFLGVPPSARPLVESVFDGRRT----YVEIVAGE
MAB_2227c|M.abscessus_ATCC_199 QLRSG----ASLADVMGYLGVPPAAQNVVESAFVGNRN----YVEVVAGQ
Rv3889c|M.tuberculosis_H37Rv LLHAV----RDAGTLRSYLLSQRLDVDQLQMVTMAADPTRSAHATLVALQ
Mb3918c|M.bovis_AF2122/97 --------------------------------------------------
MAV_0155|M.avium_104 LLASV----HDTASLRAFLLEQRLDADQLQTVLTAADSARSAHANIVALQ
MMAR_5441|M.marinum_M ELGEC----TNAAQLTRYGLTPTTARLYTEIVTNPKS-----WVEIVASE
TH_2270|M.thermoresistible__bu KLSEC----RTASELAQYGIDQASARTYSEIIADPAG-----WVEITAAE
MLBr_01540|M.leprae_Br4923 SWQDAGFNVFSGRDLRRMGISAATVAALGQALSDPAAE-----AAVYARQ
MUL_3081|M.ulcerans_Agy99 SWQESGFNVFSGGDLRRMGISASTVAALGQALSDPAAE-----VAVYARQ
Mflv_0322|M.gilvum_PYR-GCK HRDG-----HRVSTDVGVSVVDTVLGRVLVSP--AKARDGEWISTFAPGD
Mvan_0419|M.vanbaalenii_PYR-1 HRDG-----HRVSTDVGVSIVDTTAGRVLVSP--TRARDGEWISTFAPGD
MSMEG_0622|M.smegmatis_MC2_155 HRDG-----HRVTTEVGVSIIDTPHGRILVHP--TKAFDGEWISTFTPGS
MAB_2227c|M.abscessus_ATCC_199 RDST-----TQQTSEVGISVVDTSAGRILVSP--HRAGDGTWLSTFAPGA
Rv3889c|M.tuberculosis_H37Rv AGVGPEKSARILVGDSTVAIVDTAAGRICVES--VTS-GQRRYQVLSPGS
Mb3918c|M.bovis_AF2122/97 --------------------------------------------------
MAV_0155|M.avium_104 AGVGPDELARVAVGDSSVSIVDTPGGRVCIES--VVS-GQRRYQILSPGS
MMAR_5441|M.marinum_M RHPG----GTTTHTKAAAGVLDSAHGRLVSLP--RQV-GGELYGSFLPGT
TH_2270|M.thermoresistible__bu RHPG----GTTTYTDVAAGVLDSRQGRIVSLP--RRV-NGELYGSFLPGT
MLBr_01540|M.leprae_Br4923 YRDD-----AKGPSASVLSLKDSSSGRIAIYQQARTAGLGDAWLAICPAT
MUL_3081|M.ulcerans_Agy99 YRDD-----AKGPSASVLSLKDGSGGRIALYQQARTAGSGEAWLAICPAT
Mflv_0322|M.gilvum_PYR-GCK PVAIAAAVERLTAALPDG-PWFPDHALTRDFDERTAERREERCHSPL---
Mvan_0419|M.vanbaalenii_PYR-1 PIAVATAVERLTAALPDG-PWFPDQPVTRDFDSRSQ--REEICHR-----
MSMEG_0622|M.smegmatis_MC2_155 ADAIAMAVERLTASLPSG-SWFPDQPLTRDFDEDAATHREPVLQRRTQKA
MAB_2227c|M.abscessus_ATCC_199 PFAIAVAVEQLMATLPNG-HWFPDARVTRDFD------------------
Rv3889c|M.tuberculosis_H37Rv RSDIGGAVQRLIRRLPAGDEWYSYRRVV----------------------
Mb3918c|M.bovis_AF2122/97 --------------------------------------------------
MAV_0155|M.avium_104 RSDIGGAVQRLIRRLPAGDEWYSYRRVV----------------------
MMAR_5441|M.marinum_M EQNLQRALDSLLELLPSG-SWLDRADATARG-------------------
TH_2270|M.thermoresistible__bu QENLQRSLEALVGFLPAG-NWFEHTDADTAYSDGTQWN------------
MLBr_01540|M.leprae_Br4923 PQLVQLGLKTVLDTLPYG-DWKTHSRV-----------------------
MUL_3081|M.ulcerans_Agy99 PQLVQVGVKTVLDTLPYG-EWKTHSRV-----------------------