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MTGPSAAGRAGTADNVVGVEVTIDGMLVIADRLHLVDFPVTLGIRPNIPQEDLRDIVWEQVQRDLTAQGV LDLHGEPQPTVAEMVETLGRPDRTLEGRWWRRDIGGVMVRFVVCRRGDRHVIAARDGDMLVLQLVAPQVG LAGMVTAVLGPAEPANVEPLTGVATELAECTTASQLTQYGIAPASARVYAEIVGNPTGWVEIVASQRHPG GTTTQTDAAAGVLDSKLGRLVSLPRRVGGDLYGSFLPGTQQNLERALDGLLELLPAGAWLDHTSDHAQAS SRG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3866 | - | - | 100% (283) | hypothetical protein Rv3866 |
| M. tuberculosis H37Rv | Rv0289 | - | 1e-12 | 27.37% (274) | hypothetical protein Rv0289 |
| M. tuberculosis H37Rv | Rv3889c | - | 7e-09 | 26.14% (264) | hypothetical protein Rv3889c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3896 | - | 1e-163 | 100.00% (283) | hypothetical protein Mb3896 |
| M. gilvum PYR-GCK | Mflv_0775 | - | 1e-103 | 65.93% (273) | hypothetical protein Mflv_0775 |
| M. leprae Br4923 | MLBr_02530 | - | 7e-16 | 26.87% (268) | putative DNA-binding protein |
| M. abscessus ATCC 19977 | MAB_2227c | - | 5e-16 | 27.61% (268) | hypothetical protein MAB_2227c |
| M. marinum M | MMAR_5441 | - | 1e-130 | 79.86% (283) | hypothetical protein MMAR_5441 |
| M. avium 104 | MAV_4864 | - | 4e-13 | 28.21% (273) | hypothetical protein MAV_4864 |
| M. smegmatis MC2 155 | MSMEG_0057 | - | 1e-108 | 69.45% (275) | hypothetical protein MSMEG_0057 |
| M. thermoresistible (build 8) | TH_2270 | - | 1e-114 | 73.11% (264) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1211 | - | 1e-12 | 26.71% (277) | hypothetical protein MUL_1211 |
| M. vanbaalenii PYR-1 | Mvan_0070 | - | 1e-106 | 70.27% (259) | hypothetical protein Mvan_0070 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0775|M.gilvum_PYR-GCK MAYVGVRRFARVRQSYGADRRGRCRMTAPLFADGEPTHYDDVVGVELTID
Mvan_0070|M.vanbaalenii_PYR-1 -------------------------MASPFLGDGEPTHYDDVVGVEVTID
Rv3866|M.tuberculosis_H37Rv -------------------------MTGPSAAG-RAGTADNVVGVEVTID
Mb3896|M.bovis_AF2122/97 -------------------------MTGPSAAG-RAGTADNVVGVEVTID
MMAR_5441|M.marinum_M -------------------------MTGPLATG-RAGTGDDVVGVEVTID
TH_2270|M.thermoresistible__bu -------------------------MSVPQSLNPNASHIDDVVGVEVTID
MSMEG_0057|M.smegmatis_MC2_155 -------------------------MTAPFTAETGDAHIDDVVGVEVTID
MLBr_02530|M.leprae_Br4923 -------------------------------------MKVDPNAVELTVD
MAV_4864|M.avium_104 -------------------------------------MDPAPNAVELTVD
MUL_1211|M.ulcerans_Agy99 -------------------------------------MESMPNAVELTVE
MAB_2227c|M.abscessus_ATCC_199 ----------------------------------MDQANRSPDAVELTVD
.**:*::
Mflv_0775|M.gilvum_PYR-GCK GMLVIADLLHLVDFPLALGIRPNIPYEEQRKVVWDQVTHDLTAQGILTAY
Mvan_0070|M.vanbaalenii_PYR-1 GMLVIADLLHLVDFPLSLGIRPNIPYEDQRKIVWDQVTRDLTAQGILTAY
Rv3866|M.tuberculosis_H37Rv GMLVIADRLHLVDFPVTLGIRPNIPQEDLRDIVWEQVQRDLTAQGVLDLH
Mb3896|M.bovis_AF2122/97 GMLVIADRLHLVDFPVTLGIRPNIPQEDLRDIVWEQVQRDLTAQGVLDLH
MMAR_5441|M.marinum_M GMLVIADRLHLVDFPVTLGIRPNIPQEDLREIVWDQVARDLTAQGVLDHN
TH_2270|M.thermoresistible__bu GILVIADRLHLTDFPPALGIRPNIPQEDIRERVWAQVARDLAAQEVLDAH
MSMEG_0057|M.smegmatis_MC2_155 GMLVIADKLGLTDFPPSMGIRLNIPQPDLRKVVWEQVERDLSAQGVLDVY
MLBr_02530|M.leprae_Br4923 HAWFIAEVIGAGSFPWVLAITTPYRDAGERSAFVERQVDELTRMGLLVAE
MAV_4864|M.avium_104 HAWFIAETIGAGSFPWVLAITCPYRDAAERNAFLDRQRAELSEMGLVSDA
MUL_1211|M.ulcerans_Agy99 NAWFIAEMVGAGTFPWVLAITTPYSDEAQRSALFARQRDELTQLGLLSSD
MAB_2227c|M.abscessus_ATCC_199 QAWFLADTLSAGTFPWVLAVTVPFRDEAQRAGFNAQRVQELTRAGILEPD
.:*: : ** :.: * . : :*: ::
Mflv_0775|M.gilvum_PYR-GCK GDPHPEVAAMVDALSRADRTLDCRWWRR--DVGG----KMVRFVVCRKGD
Mvan_0070|M.vanbaalenii_PYR-1 GDPHPEVAAMVDALSRPDRTLDCRWWRR--DLGG----KMVRFVVCRKGD
Rv3866|M.tuberculosis_H37Rv GEPQPTVAEMVETLGRPDRTLEGRWWRR--DIGG----VMVRFVVCRRGD
Mb3896|M.bovis_AF2122/97 GEPQPTVAEMVETLGRPDRTLEGRWWRR--DIGG----VMVRFVVCRRGD
MMAR_5441|M.marinum_M GQPHPAVAAMVDTLSRADRTLEGRWWRR--DVGG----VMVRFVVCRKGE
TH_2270|M.thermoresistible__bu GRPHPEVAAMVDALSRPDRTLDGRWWRR--DVGE----KMIRFVVCRKGD
MSMEG_0057|M.smegmatis_MC2_155 GNPHPEVAAMVDTLARADRTLECRWWRR--DAGG----KMIRFVVCRKGG
MLBr_02530|M.leprae_Br4923 NSVDPTVADWIRVVCFPDRWLDLRYLRSTSAVGD---SELLRGMVAQRAG
MAV_4864|M.avium_104 GLINPAVAEWIKVVCFPQRWLDLRYVGPAKDTGEGGGSELLRGIVAQRDG
MUL_1211|M.ulcerans_Agy99 GVVNPAVAEWIKVVCFPERWLDLRYVGPGTGNGG---EDLLRGIVAQGAG
MAB_2227c|M.abscessus_ATCC_199 GTVDPAVAGWIRTVCRPDRWLELRYVAAGSENPD-----VMRGIIARKQS
. .* ** : .: .:* *: *: ::* ::.:
Mflv_0775|M.gilvum_PYR-GCK ------------RHVVAARDDDMLVLQRVAP--QIGLAAMVNVVIGAGAP
Mvan_0070|M.vanbaalenii_PYR-1 ------------RHVVAARDEDMLVLQRVAP--QIGLAAMVGVVIGGAPA
Rv3866|M.tuberculosis_H37Rv ------------RHVIAARDGDMLVLQLVAP--QVGLAGMVTAVLGPAEP
Mb3896|M.bovis_AF2122/97 ------------RHVIAARDGDMLVLQLVAP--QVGLAGMVTAVLGPAEP
MMAR_5441|M.marinum_M ------------RHVIAVRDGDMLVLQLVAP--RVGLAGMVTAVLGTAEP
TH_2270|M.thermoresistible__bu ------------RHVIAARDGDLLVLQRIAP--QVGLAGMVTAMLGPAAP
MSMEG_0057|M.smegmatis_MC2_155 ------------RHVVAARDNDLLVLQRVAP--QIGLAGMVMTVLGEGSP
MLBr_02530|M.leprae_Br4923 VSDK---------TVVALRSAQLITFTAMDIDDPLRLVPILGAGLAQRPP
MAV_4864|M.avium_104 AGGRS-------ITVVALRSAQLITFTAMDIDDPRALVPVLTVGLAQRAP
MUL_1211|M.ulcerans_Agy99 IMGKAGKAHPSFNTVVALRKAQLVTFTAMDIDDPRALVPVLGVGLSARPP
MAB_2227c|M.abscessus_ATCC_199 QGRAQ--------TVVSLRNAHLITFTVVDADDSSALVPSVVAGLRWRAP
*:: *. .::.: : *. : . : .
Mflv_0775|M.gilvum_PYR-GCK ANVEPLTG-------LAAELAEARSAEQLGRY-GQPPHSAKIYAEASASP
Mvan_0070|M.vanbaalenii_PYR-1 ADVEPLTG-------IATKLAEARTAEQIGAY-GQPPLSAKIYAEATANP
Rv3866|M.tuberculosis_H37Rv ANVEPLTG-------VATELAECTTASQLTQY-GIAPASARVYAEIVGNP
Mb3896|M.bovis_AF2122/97 ANVEPLTG-------VATELAECTTASQLTQY-GIAPASARVYAEIVGNP
MMAR_5441|M.marinum_M ANVEPLTG-------IASELGECTNAAQLTRY-GLTPTTARLYTEIVTNP
TH_2270|M.thermoresistible__bu ADVEPLTG-------LASKLSECRTASELAQY-GIDQASARTYSEIIADP
MSMEG_0057|M.smegmatis_MC2_155 ANVEPLTG-------VADRLAQCRTAEELTGY-GIPPTSARAYASIISEP
MLBr_02530|M.leprae_Br4923 ARFDEFSMPMRVGVRADERLRSGTSLAEVADYLGIPKSAQPVVESVFSGP
MAV_4864|M.avium_104 ASFDEFSMPTRVGARADERLRAGAPLSEVLDYLGIPQSARPVVESVFNGP
MUL_1211|M.ulcerans_Agy99 ARFEEFSMPMRVGARADERLRSGESLDEVLDYLGIPVSARPVVQAVFSGP
MAB_2227c|M.abscessus_ATCC_199 ARFPEFTLPTNVGAKADEQLRSGASLADVMGYLGVPPAAQNVVESAFVGN
* . :: .* :: * * :
Mflv_0775|M.gilvum_PYR-GCK DSWVEITANERHPGGTYSQAGVGAGVLDSSHGRIVSIP-RRVNGDLYGSF
Mvan_0070|M.vanbaalenii_PYR-1 DSWVEITAAERHPGGTYSQAGVGAGVLDSAHGRIVSIP-RQVGGELYGSF
Rv3866|M.tuberculosis_H37Rv TGWVEIVASQRHPGGTTTQTDAAAGVLDSKLGRLVSLP-RRVGGDLYGSF
Mb3896|M.bovis_AF2122/97 TGWVEIVASQRHPGGTTTQTDAAAGVLDSKLGRLVSLP-RRVGGDLYGSF
MMAR_5441|M.marinum_M KSWVEIVASERHPGGTTTHTKAAAGVLDSAHGRLVSLP-RQVGGELYGSF
TH_2270|M.thermoresistible__bu AGWVEITAAERHPGGTTTYTDVAAGVLDSRQGRIVSLP-RRVNGELYGSF
MSMEG_0057|M.smegmatis_MC2_155 DGWVEIVANERHPGGTTSQVDVAAGVLDAKQGRIVSIP-RRVNGELYGSF
MLBr_02530|M.leprae_Br4923 RSYVEIVAGCRRDG-KHATTEVGMSIVDTTTGRVLVNPSRAFDGEWVSTF
MAV_4864|M.avium_104 RSYVEIVAGCHRDG-RHSTTEVGMSIVDAREGRVLVSPSRAFDGEWVSTF
MUL_1211|M.ulcerans_Agy99 RSYVEIVAGCNRDG-EHTTTDVGLSIVDTTAGRVLVSPSRAFDGEWVSTF
MAB_2227c|M.abscessus_ATCC_199 RNYVEVVAGQRDST-TQQTSEVGISVVDTSAGRILVSPHRAGDGTWLSTF
.:**:.* . .. .::*: **:: * * .* .:*
Mflv_0775|M.gilvum_PYR-GCK LPGTPENLQRALDGLIEFLPSATWFEHRDAAEGPVDE-----
Mvan_0070|M.vanbaalenii_PYR-1 LPGTQENLQRALDGLVEFLPSRAWFDHADALDNSYSD-----
Rv3866|M.tuberculosis_H37Rv LPGTQQNLERALDGLLELLPAGAWLDHTSDHAQASSRG----
Mb3896|M.bovis_AF2122/97 LPGTQQNLERALDGLLELLPAGAWLDHTSDHAQASSRG----
MMAR_5441|M.marinum_M LPGTEQNLQRALDSLLELLPSGSWLDR----ADATARG----
TH_2270|M.thermoresistible__bu LPGTQENLQRSLEALVGFLPAGNWFEHT-DADTAYSDGTQWN
MSMEG_0057|M.smegmatis_MC2_155 LSGTKDNLERALEGLVEFLPSKTWFDKT-DADNAYQH-----
MLBr_02530|M.leprae_Br4923 SPGTPFAIAVGIEQLTATLPEGQWFPGQRLCRDFSGQTS---
MAV_4864|M.avium_104 SPGTPFAIAVAIEHLTALLPDDGWFAGHRLARDFSVQH----
MUL_1211|M.ulcerans_Agy99 SAGTPFATAVAIDQLIANLPDGQWFPGQRLSRDFSSQPS---
MAB_2227c|M.abscessus_ATCC_199 APGAPFAIAVAVEQLMATLPNGHWFPDARVTRDFD-------
.*: .:: * ** *: