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VHADAVELTAEAAWFLADTLGAGTFPWVLAITPPYSDRSQRAQFESEQAERLTRMGVMDADRAVDAAVAR WIRLVCRPTQWLELRFVGARGAMLRGIIARDASRTVVALRSGGLITLTEMQIDHPQALVPVLTVGLSGRS PARFPEFSLPARVGAKADDQIRRGASVRDLLDYLGVPPSARPVVVAAFEEARTYVEIVAGRHRDGHRVST DVGVSIVDTTAGRVLVSPTRARDGEWISTFAPGDPIAVATAVERLTAALPDGPWFPDQPVTRDFDSRSQR EEICHR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0419 | - | - | 100% (286) | putative DNA-binding protein |
| M. vanbaalenii PYR-1 | Mvan_0070 | - | 1e-14 | 28.95% (266) | hypothetical protein Mvan_0070 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0297 | - | 1e-91 | 56.75% (289) | hypothetical protein Mb0297 |
| M. gilvum PYR-GCK | Mflv_0322 | - | 1e-129 | 76.66% (287) | putative DNA-binding protein |
| M. tuberculosis H37Rv | Rv0289 | - | 1e-91 | 56.75% (289) | hypothetical protein Rv0289 |
| M. leprae Br4923 | MLBr_02530 | - | 9e-89 | 54.55% (286) | putative DNA-binding protein |
| M. abscessus ATCC 19977 | MAB_2227c | - | 2e-89 | 58.06% (279) | hypothetical protein MAB_2227c |
| M. marinum M | MMAR_0548 | - | 8e-92 | 57.39% (291) | hypothetical protein MMAR_0548 |
| M. avium 104 | MAV_4864 | - | 6e-86 | 56.34% (284) | hypothetical protein MAV_4864 |
| M. smegmatis MC2 155 | MSMEG_0622 | - | 1e-103 | 63.19% (288) | putative DNA-binding protein |
| M. thermoresistible (build 8) | TH_2109 | - | 1e-94 | 59.35% (278) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1211 | - | 4e-91 | 57.04% (291) | hypothetical protein MUL_1211 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0297|M.bovis_AF2122/97 ---MDATPNAVELTVDNAWFIAETIGAGTFPWVLAITMPYSDAAQRGAFV
Rv0289|M.tuberculosis_H37Rv ---MDATPNAVELTVDNAWFIAETIGAGTFPWVLAITMPYSDAAQRGAFV
MMAR_0548|M.marinum_M ---MESMPNAVELTVENAWFIAEMVGAGTFPWVLAITTPYSDEAQRSAFF
MUL_1211|M.ulcerans_Agy99 ---MESMPNAVELTVENAWFIAEMVGAGTFPWVLAITTPYSDEAQRSALF
MAV_4864|M.avium_104 ---MDPAPNAVELTVDHAWFIAETIGAGSFPWVLAITCPYRDAAERNAFL
MLBr_02530|M.leprae_Br4923 ---MKVDPNAVELTVDHAWFIAEVIGAGSFPWVLAITTPYRDAGERSAFV
MAB_2227c|M.abscessus_ATCC_199 MDQANRSPDAVELTVDQAWFLADTLSAGTFPWVLAVTVPFRDEAQRAGFN
Mvan_0419|M.vanbaalenii_PYR-1 -----MHADAVELTAEAAWFLADTLGAGTFPWVLAITPPYSDRSQRAQFE
Mflv_0322|M.gilvum_PYR-GCK -----MRANAVELSAASAWFLAEELGAGSYPWVLAITPPYSDVSARGPFE
MSMEG_0622|M.smegmatis_MC2_155 -----MGPNAVELTTDQAWCLADVLGAGSYPWVLAITPPYSDHSQRSAFL
TH_2109|M.thermoresistible__bu VPDTGSGPNAIELTVEQAWYLAEELDAGGYPWVLAVTPPYSDPADAAEFR
.:*:**:. ** :*: :.** :*****:* *: * . :
Mb0297|M.bovis_AF2122/97 DRQRDELTRMGLLSPQGVINPAVADWIKVVCFPDRWLDLRYVGPASADG-
Rv0289|M.tuberculosis_H37Rv DRQRDELTRMGLLSPQGVINPAVADWIKVVCFPDRWLDLRYVGPASADG-
MMAR_0548|M.marinum_M ARQRDELTQLGLLSSDGVVNPAVAEWIKVVCFPERWLDLRYVGPGTGNG-
MUL_1211|M.ulcerans_Agy99 ARQRDELTQLGLLSSDGVVNPAVAEWIKVVCFPERWLDLRYVGPGTGNG-
MAV_4864|M.avium_104 DRQRAELSEMGLVSDAGLINPAVAEWIKVVCFPQRWLDLRYVGPAKDTGE
MLBr_02530|M.leprae_Br4923 ERQVDELTRMGLLVAENSVDPTVADWIRVVCFPDRWLDLRYLRSTSAVG-
MAB_2227c|M.abscessus_ATCC_199 AQRVQELTRAGILEPDGTVDPAVAGWIRTVCRPDRWLELRYVAAGSENP-
Mvan_0419|M.vanbaalenii_PYR-1 SEQAERLTRMGVMDADRAVDAAVARWIRLVCRPTQWLELRFVGA---RG-
Mflv_0322|M.gilvum_PYR-GCK REQTEKLRGAGIMTAERTVDPAVARWIRRVCRPTQWLELRFVGS---RG-
MSMEG_0622|M.smegmatis_MC2_155 AAQSAELTRMGVVNSAGAVDPRVAQWITTVCRATQWLDLRFVSG---PG-
TH_2109|M.thermoresistible__bu SDQRDELTGLGVLDADGRVGDTVARWVRTVCRPDRWLDLRFVTG---VG-
: .* *:: :. ** *: ** . :**:**::
Mb0297|M.bovis_AF2122/97 --ACELLRGIVALRTGTGKTSNKTG---NGVVALRNAQLVTFTAMDIDDP
Rv0289|M.tuberculosis_H37Rv --ACELLRGIVALRTGTGKTSNKTG---NGVVALRNAQLVTFTAMDIDDP
MMAR_0548|M.marinum_M --GEDLLRGIVAQSAGIMGKAGKAHPSFNTVVALRNAQLVTFTAMDIDDP
MUL_1211|M.ulcerans_Agy99 --GEDLLRGIVAQGAGIMGKAGKAHPSFNTVVALRKAQLVTFTAMDIDDP
MAV_4864|M.avium_104 GGGSELLRGIVAQRDGAGGRS-------ITVVALRSAQLITFTAMDIDDP
MLBr_02530|M.leprae_Br4923 --DSELLRGMVAQRAGVSDKT---------VVALRSAQLITFTAMDIDDP
MAB_2227c|M.abscessus_ATCC_199 ----DVMRGIIARKQSQGRAQ--------TVVSLRNAHLITFTVVDADDS
Mvan_0419|M.vanbaalenii_PYR-1 ----AMLRGIIARDASR------------TVVALRSGGLITLTEMQIDHP
Mflv_0322|M.gilvum_PYR-GCK ----AVLRGVLARDGAG------------TVIALRSGGLITLTELDIDHP
MSMEG_0622|M.smegmatis_MC2_155 ----DLLRGMVARRSEE------------TVVALRNAQLVTFTAMDIGHQ
TH_2109|M.thermoresistible__bu ----DILRGVVARRDDR------------TVVALRNAELITFTAMAIDHP
::**::* *::**.. *:*:* : ..
Mb0297|M.bovis_AF2122/97 RALVPILGVGLAHRPPARFDEFSLPTRVGARADERLRSGVPLGEVVDYLG
Rv0289|M.tuberculosis_H37Rv RALVPILGVGLAHRPPARFDEFSLPTRVGARADERLRSGVPLGEVVDYLG
MMAR_0548|M.marinum_M RALVPVLGVGLSARPPARFEEFSMPMRVGARADERLRSGESLDEVLDYLG
MUL_1211|M.ulcerans_Agy99 RALVPVLGVGLSARPPARFEEFSMPMRVGARADERLRSGESLDEVLDYLG
MAV_4864|M.avium_104 RALVPVLTVGLAQRAPASFDEFSMPTRVGARADERLRAGAPLSEVLDYLG
MLBr_02530|M.leprae_Br4923 LRLVPILGAGLAQRPPARFDEFSMPMRVGVRADERLRSGTSLAEVADYLG
MAB_2227c|M.abscessus_ATCC_199 SALVPSVVAGLRWRAPARFPEFTLPTNVGAKADEQLRSGASLADVMGYLG
Mvan_0419|M.vanbaalenii_PYR-1 QALVPVLTVGLSGRSPARFPEFSLPARVGAKADDQIRRGASVRDLLDYLG
Mflv_0322|M.gilvum_PYR-GCK EALVPVVTAGLSGRAPARFDGFSLPARVGAKADEQIRKGAAVGGLLDYLG
MSMEG_0622|M.smegmatis_MC2_155 HALVPVLTAGLSGRKPARFDDFALPAAAGARADEQIRNGAPLAEVLEFLG
TH_2109|M.thermoresistible__bu QALVPVLTAGLANRPPARFATFALPADAGARADERIRNGADLAEVMEFLG
*** : .** * ** * *::* .*.:**:::* * : : :**
Mb0297|M.bovis_AF2122/97 IPASARPVVESVFSGPRSYVEIVAGCNRDGRHTTTEVGLSIVDTSAGRVL
Rv0289|M.tuberculosis_H37Rv IPASARPVVESVFSGPRSYVEIVAGCNRDGRHTTTEVGLSIVDTSAGRVL
MMAR_0548|M.marinum_M IPVSARPVVQAVFSGPRSYVEIVAGCNRDGEHTTTDVGLSIVDTTAGRVL
MUL_1211|M.ulcerans_Agy99 IPVSARPVVQAVFSGPRSYVEIVAGCNRDGEHTTTDVGLSIVDTTAGRVL
MAV_4864|M.avium_104 IPQSARPVVESVFNGPRSYVEIVAGCHRDGRHSTTEVGMSIVDAREGRVL
MLBr_02530|M.leprae_Br4923 IPKSAQPVVESVFSGPRSYVEIVAGCRRDGKHATTEVGMSIVDTTTGRVL
MAB_2227c|M.abscessus_ATCC_199 VPPAAQNVVESAFVGNRNYVEVVAGQRDSTTQQTSEVGISVVDTSAGRIL
Mvan_0419|M.vanbaalenii_PYR-1 VPPSARPVVVAAFEEARTYVEIVAGRHRDGHRVSTDVGVSIVDTTAGRVL
Mflv_0322|M.gilvum_PYR-GCK IPPSARPVVVAAFEDSRTYVEIVAGQHRDGHRVSTDVGVSVVDTVLGRVL
MSMEG_0622|M.smegmatis_MC2_155 VPPSARPLVESVFDGRRTYVEIVAGEHRDGHRVTTEVGVSIIDTPHGRIL
TH_2109|M.thermoresistible__bu IPLSARPVVEAAFDHRRRYVEIVAGERANGNQLSTEVGVSIVDTALGRVL
:* :*: :* :.* * ***:*** . . : :::**:*::*: **:*
Mb0297|M.bovis_AF2122/97 VSPSRAFDGEWVSTFSPGTPFAIAVAIQTLTACLPDGQWFPGQRVSRDFS
Rv0289|M.tuberculosis_H37Rv VSPSRAFDGEWVSTFSPGTPFAIAVAIQTLTACLPDGQWFPGQRVSRDFS
MMAR_0548|M.marinum_M VSPSRAFDGEWVSTFSAGTPFATAVAIDQLIANLPDGQWFPGQRLSRDFS
MUL_1211|M.ulcerans_Agy99 VSPSRAFDGEWVSTFSAGTPFATAVAIDQLIANLPDGQWFPGQRLSRDFS
MAV_4864|M.avium_104 VSPSRAFDGEWVSTFSPGTPFAIAVAIEHLTALLPDDGWFAGHRLARDFS
MLBr_02530|M.leprae_Br4923 VNPSRAFDGEWVSTFSPGTPFAIAVGIEQLTATLPEGQWFPGQRLCRDFS
MAB_2227c|M.abscessus_ATCC_199 VSPHRAGDGTWLSTFAPGAPFAIAVAVEQLMATLPNGHWFPDARVTRDFD
Mvan_0419|M.vanbaalenii_PYR-1 VSPTRARDGEWISTFAPGDPIAVATAVERLTAALPDGPWFPDQPVTRDFD
Mflv_0322|M.gilvum_PYR-GCK VSPAKARDGEWISTFAPGDPVAIAAAVERLTAALPDGPWFPDHALTRDFD
MSMEG_0622|M.smegmatis_MC2_155 VHPTKAFDGEWISTFTPGSADAIAMAVERLTASLPSGSWFPDQPLTRDFD
TH_2109|M.thermoresistible__bu VSPEQAFDGEWVSTFEPGTTDSIAAAVERLIATLPGGTWFPHLARARDFD
* * :* ** *:*** .* . : * .:: * * ** . **. ***.
Mb0297|M.bovis_AF2122/97 TQSS--------------
Rv0289|M.tuberculosis_H37Rv TQSS--------------
MMAR_0548|M.marinum_M SQPS--------------
MUL_1211|M.ulcerans_Agy99 SQPS--------------
MAV_4864|M.avium_104 VQH---------------
MLBr_02530|M.leprae_Br4923 GQTS--------------
MAB_2227c|M.abscessus_ATCC_199 ------------------
Mvan_0419|M.vanbaalenii_PYR-1 SRSQ--REEICHR-----
Mflv_0322|M.gilvum_PYR-GCK ERTAERREERCHSPL---
MSMEG_0622|M.smegmatis_MC2_155 EDAATHREPVLQRRTQKA
TH_2109|M.thermoresistible__bu HRTEMQRRGPCPTTP---