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MLTTTVDGLWVLQAVTGIEQTCPELGLRPLLPRLDTPERALRHPAAAELVAAGALDEAGNVDPMIREWLT VLLRRDLGLLVMIAVPGREPSRASICRFATWWVVLERHDQLVRLYPAGTASSEAAASEIVVGQIERLCGV AEAAPLRPITLDTEQLLASVHDTASLRAFLLEQRLDADQLQTVLTAADSARSAHANIVALQAGVGPDELA RVAVGDSSVSIVDTPGGRVCIESVVSGQRRYQILSPGSRSDIGGAVQRLIRRLPAGDEWYSYRRVV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0155 | - | - | 100% (276) | hypothetical protein MAV_0155 |
| M. avium 104 | MAV_2920 | - | 4e-07 | 23.59% (301) | hypothetical protein MAV_2920 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3918c | - | 1e-31 | 88.24% (68) | hypothetical protein Mb3918c |
| M. gilvum PYR-GCK | Mflv_0775 | - | 7e-05 | 24.82% (278) | hypothetical protein Mflv_0775 |
| M. tuberculosis H37Rv | Rv3889c | - | 1e-129 | 80.07% (276) | hypothetical protein Rv3889c |
| M. leprae Br4923 | MLBr_01540 | - | 9e-06 | 22.00% (300) | hypothetical protein MLBr_01540 |
| M. abscessus ATCC 19977 | MAB_2227c | - | 7e-07 | 26.74% (288) | hypothetical protein MAB_2227c |
| M. marinum M | MMAR_2676 | - | 2e-05 | 24.19% (310) | hypothetical protein MMAR_2676 |
| M. smegmatis MC2 155 | MSMEG_0622 | - | 1e-09 | 26.09% (276) | putative DNA-binding protein |
| M. thermoresistible (build 8) | TH_2270 | - | 4e-07 | 25.27% (277) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3081 | - | 3e-05 | 23.87% (310) | hypothetical protein MUL_3081 |
| M. vanbaalenii PYR-1 | Mvan_0419 | - | 8e-05 | 25.00% (272) | putative DNA-binding protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3918c|M.bovis_AF2122/97 -------------------------------------------MLTTTVD
Rv3889c|M.tuberculosis_H37Rv -------------------------------------------MLTTTVD
MAV_0155|M.avium_104 -------------------------------------------MLTTTVD
MSMEG_0622|M.smegmatis_MC2_155 -------------------------------MGPN--------AVELTTD
Mvan_0419|M.vanbaalenii_PYR-1 -------------------------------MHAD--------AVELTAE
MAB_2227c|M.abscessus_ATCC_199 --------------------------MDQANRSPD--------AVELTVD
Mflv_0775|M.gilvum_PYR-GCK MAYVGVRRFARVRQSYGADRRGRCRMTAPLFADGEPTHYDDVVGVELTID
TH_2270|M.thermoresistible__bu -------------------------MSVPQSLNPNASHIDDVVGVEVTID
MMAR_2676|M.marinum_M --------------------------MDQQSTRTD---------ITVNVD
MUL_3081|M.ulcerans_Agy99 --------------------------MDQQSTRTD---------ITVNVD
MLBr_01540|M.leprae_Br4923 --------------------------MDHQSTRTD---------ITVNVD
: . :
Mb3918c|M.bovis_AF2122/97 GLWVLQAVTGVEQTCPELGLRPLLPRLDTAERALRHPVAAELMAVGALDQ
Rv3889c|M.tuberculosis_H37Rv GLWVLQAVTGVEQTCPELGLRPLLPRLDTAERALRHPVAAELMAVGALDQ
MAV_0155|M.avium_104 GLWVLQAVTGIEQTCPELGLRPLLPRLDTPERALRHPAAAELVAAGALDE
MSMEG_0622|M.smegmatis_MC2_155 QAWCLADVLGAGSYPWVLAITPPYS-DHSQRSAFLAAQSAELTRMGVVNS
Mvan_0419|M.vanbaalenii_PYR-1 AAWFLADTLGAGTFPWVLAITPPYS-DRSQRAQFESEQAERLTRMGVMDA
MAB_2227c|M.abscessus_ATCC_199 QAWFLADTLSAGTFPWVLAVTVPFR-DEAQRAGFNAQRVQELTRAGILEP
Mflv_0775|M.gilvum_PYR-GCK GMLVIADLLHLVDFPLALGIRPNIP-YEEQRKVVWDQVTHDLTAQGILTA
TH_2270|M.thermoresistible__bu GILVIADRLHLTDFPPALGIRPNIP-QEDIRERVWAQVARDLAAQEVLDA
MMAR_2676|M.marinum_M GFWMLQALLDIRHVAPELRCRPYVS--TDSNDWLNEHPGMAVMREQGIVV
MUL_3081|M.ulcerans_Agy99 GFWMLQALLDIRHVAPELRCRPYVS--TDSNDWLNEHPGMAVMREQGIVV
MLBr_01540|M.leprae_Br4923 GFWLLQALLDIRHVAPELRCRPFVS--TDSNDWLHEHPGMAVMREQGIVV
: * . . : :
Mb3918c|M.bovis_AF2122/97 AGNADPMVREWR--LMR---------------------------------
Rv3889c|M.tuberculosis_H37Rv AGNADPMVREWLTVLLRRDLGLLVTIGVPGGE------------------
MAV_0155|M.avium_104 AGNVDPMIREWLTVLLRRDLGLLVMIAVPGRE------------------
MSMEG_0622|M.smegmatis_MC2_155 AGAVDPRVAQWITTVCRATQWLDLRFVSGPG-------------------
Mvan_0419|M.vanbaalenii_PYR-1 DRAVDAAVARWIRLVCRPTQWLELRFVGARG-------------------
MAB_2227c|M.abscessus_ATCC_199 DGTVDPAVAGWIRTVCRPDRWLELRYVAAGSEN----------------P
Mflv_0775|M.gilvum_PYR-GCK YGDPHPEVAAMVDALSRADRTLDCRWWRRDVG-----------------G
TH_2270|M.thermoresistible__bu HGRPHPEVAAMVDALSRPDRTLDGRWWRRDVG-----------------E
MMAR_2676|M.marinum_M GDTVNEQVAARMRVLAAPDLEVVALLSRGKLLYGVVDNEDQPPGSRDIPD
MUL_3081|M.ulcerans_Agy99 GDTLNEQVAARMRVLAAPDLEVVALLSRGKLLYGVVDNEDQPPGSRDIPD
MLBr_01540|M.leprae_Br4923 NGNVNEHVATRMRVFAAPDLEVVALLSRGKLLYGAVNDENQPPGSRDIPE
. : .
Mb3918c|M.bovis_AF2122/97 --------------------------------------------------
Rv3889c|M.tuberculosis_H37Rv -PTRAAICRFATW----WVVLERHGNLVRLYPAGTASDEAGAGELVVGQV
MAV_0155|M.avium_104 -PSRASICRFATW----WVVLERHDQLVRLYPAGTASSEAAASEIVVGQI
MSMEG_0622|M.smegmatis_MC2_155 DLLRGMVARRSEE----TVVALRNAQLVTFTAMDIGHQHALVPVLTAGLS
Mvan_0419|M.vanbaalenii_PYR-1 AMLRGIIARDASR----TVVALRSGGLITLTEMQIDHPQALVPVLTVGLS
MAB_2227c|M.abscessus_ATCC_199 DVMRGIIARKQSQGRAQTVVSLRNAHLITFTVVDADDSSALVPSVVAGLR
Mflv_0775|M.gilvum_PYR-GCK KMVRFVVCRKGDR----HVVAARDDDMLVLQRVAP--QIGLAAMVNVVIG
TH_2270|M.thermoresistible__bu KMIRFVVCRKGDR----HVIAARDGDLLVLQRIAP--QVGLAGMVTAMLG
MMAR_2676|M.marinum_M NEFRVVLARRGQH----WVSAVRVGNDITVDDVSVSDSASIAALVIDGLE
MUL_3081|M.ulcerans_Agy99 NEFRVVLARRGQH----WVSAVRVGNDITVDDVSVSDSASIAALVIDGLE
MLBr_01540|M.leprae_Br4923 NEFRVVLVRRGSH----WASAVRVGNDITIDDVAIADSASITSLVMDGLE
Mb3918c|M.bovis_AF2122/97 --------------------------------------------------
Rv3889c|M.tuberculosis_H37Rv ERLCGV-AEAAPLRPVTVDADELLHAVRDAGTLRSYLLSQRLDVDQLQMV
MAV_0155|M.avium_104 ERLCGV-AEAAPLRPITLDTEQLLASVHDTASLRAFLLEQRLDADQLQTV
MSMEG_0622|M.smegmatis_MC2_155 GRKP---ARFDDFALPAAAGARADEQIRNGAPLAEVLEFLGVPPSARPLV
Mvan_0419|M.vanbaalenii_PYR-1 GRSP---ARFPEFSLPARVGAKADDQIRRGASVRDLLDYLGVPPSARPVV
MAB_2227c|M.abscessus_ATCC_199 WRAP---ARFPEFTLPTNVGAKADEQLRSGASLADVMGYLGVPPAAQNVV
Mflv_0775|M.gilvum_PYR-GCK AGAP---ANVEPLTGLAAELAEARS--------AEQLGRYGQPPHSAKIY
TH_2270|M.thermoresistible__bu PAAP---ADVEPLTGLASKLSECRT--------ASELAQYGIDQASARTY
MMAR_2676|M.marinum_M SIHHADPAAINAVNVPLEEMLEATKSWQESGFNVFSGGDLRRMGISASTV
MUL_3081|M.ulcerans_Agy99 SIHHADPAAINAVNVPLEEMLEATKSWQESGFNVFSGGDLRRMGISASTV
MLBr_01540|M.leprae_Br4923 SIHHADPAAINAVNVPLEEMLEATKSWQDAGFNVFSGRDLRRMGISAATV
Mb3918c|M.bovis_AF2122/97 --------------------------------------------------
Rv3889c|M.tuberculosis_H37Rv TMAADPTRSAHATLVALQAGVGPEKSARILVGDSTVAIVDTAAGRICVES
MAV_0155|M.avium_104 LTAADSARSAHANIVALQAGVGPDELARVAVGDSSVSIVDTPGGRVCIES
MSMEG_0622|M.smegmatis_MC2_155 ESVFDGRR-TYVEIVAGE-----HRDGHRVTTEVGVSIIDTPHGRILVHP
Mvan_0419|M.vanbaalenii_PYR-1 VAAFEEAR-TYVEIVAGR-----HRDGHRVSTDVGVSIVDTTAGRVLVSP
MAB_2227c|M.abscessus_ATCC_199 ESAFVGNR-NYVEVVAGQ-----RDSTTQQTSEVGISVVDTSAGRILVSP
Mflv_0775|M.gilvum_PYR-GCK AEASASPD-SWVEITANER----HPGGTYSQAGVGAGVLDSSHGRIVSIP
TH_2270|M.thermoresistible__bu SEIIADPA-GWVEITAAER----HPGGTTTYTDVAAGVLDSRQGRIVSLP
MMAR_2676|M.marinum_M AALGQALSDPAAEVAVYAR---QYRDDAKGPSASVLSLKDGSGGRIALYQ
MUL_3081|M.ulcerans_Agy99 AALGQALSDPAAEVAVYAR---QYRDDAKGPSASVLSLKDGSGGRIALYQ
MLBr_01540|M.leprae_Br4923 AALGQALSDPAAEAAVYAR---QYRDDAKGPSASVLSLKDSSSGRIAIYQ
Mb3918c|M.bovis_AF2122/97 --------------------------------------------------
Rv3889c|M.tuberculosis_H37Rv --VTSG-QRRYQVLSPGSRSDIGGAVQRLIRRLPAGDEWYSYRRVV----
MAV_0155|M.avium_104 --VVSG-QRRYQILSPGSRSDIGGAVQRLIRRLPAGDEWYSYRRVV----
MSMEG_0622|M.smegmatis_MC2_155 --TKAFDGEWISTFTPGSADAIAMAVERLTASLPSG-SWFPDQPLTRDFD
Mvan_0419|M.vanbaalenii_PYR-1 --TRARDGEWISTFAPGDPIAVATAVERLTAALPDG-PWFPDQPVTRDFD
MAB_2227c|M.abscessus_ATCC_199 --HRAGDGTWLSTFAPGAPFAIAVAVEQLMATLPNG-HWFPDARVTRDFD
Mflv_0775|M.gilvum_PYR-GCK --RRVN-GDLYGSFLPGTPENLQRALDGLIEFLPSA-TWFEHRDAAEGPV
TH_2270|M.thermoresistible__bu --RRVN-GELYGSFLPGTQENLQRSLEALVGFLPAG-NWFEHTDADTAYS
MMAR_2676|M.marinum_M QARTAGSGEAWLAICPATPQLVQVGVKTVLDTLPYG-EWKTHSRV-----
MUL_3081|M.ulcerans_Agy99 QARTAGSGEAWLAICPATPQLVQVGVKTVLDTLPYG-EWKTHSRV-----
MLBr_01540|M.leprae_Br4923 QARTAGLGDAWLAICPATPQLVQLGLKTVLDTLPYG-DWKTHSRV-----
Mb3918c|M.bovis_AF2122/97 ------------------
Rv3889c|M.tuberculosis_H37Rv ------------------
MAV_0155|M.avium_104 ------------------
MSMEG_0622|M.smegmatis_MC2_155 EDAATHREPVLQRRTQKA
Mvan_0419|M.vanbaalenii_PYR-1 S--RSQREEICHR-----
MAB_2227c|M.abscessus_ATCC_199 ------------------
Mflv_0775|M.gilvum_PYR-GCK DE----------------
TH_2270|M.thermoresistible__bu DGTQWN------------
MMAR_2676|M.marinum_M ------------------
MUL_3081|M.ulcerans_Agy99 ------------------
MLBr_01540|M.leprae_Br4923 ------------------