For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TSKLTGFSPRSARRVAGVWTVFVLASAGWALGGQLGAVMAVVVGVALVFVQWWGQPAWSWAVLGLRGRRP VKWNDPITLANNRSGGGVRVQDGVAVVAVQLLGRAHRATTVTGSVTVESDNVIDVVELAPLLRHPLDLEL DSISVVTFGSRTGTVGDYPRVYDAEIGTPPYAGRRETWLIMRLPVIGNTQALRWRTSVGAAAISVAQRVA SSLRCQGLRAKLATATDLAELDRRLGSDAVAGSAQRWKAIRGEAGWMTTYAYPAEAISSRVLSQAWTLRA DEVIQNVTVYPDATCTATITVRTPTPAPTPPSVILRRLNGEQAAAAAANMCGPRPHLRGQRRCPLPAQLV TEIGPSGVLIGKLSNGDRLMIPVTDAGELSRVFVAADDTIAKRIVIRVVGAGERVCVHTRDQERWASVRM PQLSIVGTPRPAPRTTVGVVEYVRRRKNGDDGKSEGSGVDVAISPTPRPASVITIARPGTSLSESDRHGF EVTIEQIDRATVKVGAAGQNWLVEMEMFRAENRYVSLEPVTMSIGR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3885c | - | - | 100% (537) | POSSIBLE CONSERVED MEMBRANE PROTEIN |
| M. tuberculosis H37Rv | Rv3882c | - | 6e-19 | 26.75% (385) | hypothetical protein Rv3882c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3915c | - | 0.0 | 99.81% (537) | hypothetical protein Mb3915c |
| M. gilvum PYR-GCK | Mflv_0756 | - | 1e-16 | 27.08% (384) | hypothetical protein Mflv_0756 |
| M. leprae Br4923 | MLBr_00042 | - | 2e-16 | 26.84% (380) | hypothetical protein MLBr_00042 |
| M. abscessus ATCC 19977 | MAB_3760 | - | 4e-12 | 21.66% (397) | hypothetical protein MAB_3760 |
| M. marinum M | MMAR_5458 | - | 1e-14 | 26.61% (357) | hypothetical protein MMAR_5458 |
| M. avium 104 | MAV_0159 | - | 0.0 | 79.32% (532) | hypothetical protein MAV_0159 |
| M. smegmatis MC2 155 | MSMEG_0082 | - | 1e-11 | 24.24% (396) | hypothetical protein MSMEG_0082 |
| M. thermoresistible (build 8) | TH_1275 | - | 7e-16 | 25.92% (382) | POSSIBLE CONSERVED MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_3078 | - | 1e-14 | 26.92% (234) | hypothetical protein MUL_3078 |
| M. vanbaalenii PYR-1 | Mvan_0091 | - | 5e-14 | 23.41% (440) | hypothetical protein Mvan_0091 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0082|M.smegmatis_MC2_155 MNFLR-QFGFRFTTGHGIWAATLIPACIAICMHFDL---------LWLGI
TH_1275|M.thermoresistible__bu MKSLRNLFGMRFSTGHGIWAAVLIPAVVVLFERLEM---------LWLGV
Mflv_0756|M.gilvum_PYR-GCK MSRFLSIFGVRFTTGHALWAAVLVPACILIFAQLNL---------LWLGI
Mvan_0091|M.vanbaalenii_PYR-1 MSRFASIFGLRFTTGHALWAAALIPACILVFARLEL---------LWLGI
MLBr_00042|M.leprae_Br4923 MRNP---VWLRFSMGRALLVTALVPPCIILFFHTQY---------WWAGI
MMAR_5458|M.marinum_M MRNPFSSIRFRVSTGHTLVVAVLAPPCIMMFLHMRY---------WWVGI
Rv3885c|M.tuberculosis_H37Rv -------MTSKLTGFSPRSARRVAGVWTVFVLASAG---------WALGG
Mb3915c|M.bovis_AF2122/97 -------MTSKLTGFSPRSARRVAGVWTVFVLASAG---------WALGG
MAV_0159|M.avium_104 -------MRPNLTGFSRGSNRRVVGVWVVFVLALAS---------WLLGG
MAB_3760|M.abscessus_ATCC_1997 MTSSGAAPEQVRRATMPIQIMVISQLLVLAAVLISL---------LFGWP
MUL_3078|M.ulcerans_Agy99 -MKAQRRFGLALSWARLTTVFVIDLLILIVASHCPDSWQGENRIAWWVGV
:
MSMEG_0082|M.smegmatis_MC2_155 TLGALIALFSVLTIRGLRIT-GWVRAIFSWRRRHRSTPDIASEPAVGSTV
TH_1275|M.thermoresistible__bu VVAVFIAPASVLTIRGRRLT-GWVAAVFSWRRRHRVPPARPSEPAVGATV
Mflv_0756|M.gilvum_PYR-GCK TLAVLIALCALVTIRGRRIT-GWIAALFAWRRRHRQPPPAPSEPAVGATV
Mvan_0091|M.vanbaalenii_PYR-1 TLGVLIGLASVVTIRGRRLT-GWVAALFAWRRRHRQPPPTPSEPAVGATV
MLBr_00042|M.leprae_Br4923 ALVVLVVILTLVEFSGRWLS-GWLMALYSFFRRSSKPLDTPSEPVIGATV
MMAR_5458|M.marinum_M ALVALGVIVATVTFSGRRVT-GWVATVFAWLRRRRRPPDVPSEPVVGATV
Rv3885c|M.tuberculosis_H37Rv QLGAVMAVVVGVALVFVQWW-GQPAWSWAVLGLRGRRPVKWNDPITLANN
Mb3915c|M.bovis_AF2122/97 QLGAVMAVVVGVALVFVQWW-GQPAWSWAVLGLRGRRPVKWNDPITLANN
MAV_0159|M.avium_104 YIAAAVAVLVGVALVFVRWW-GQPAWSWAVLWRRGRRPIDWSAPITVANN
MAB_3760|M.abscessus_ATCC_1997 WWAALLIAIVSLALVLGRWG-GQTVRHWAVTGFKYLTGRTYRSSGSIADT
MUL_3078|M.ulcerans_Agy99 GIAVLVTLLSVVTYRGITVTSGITAWLWDWSADPGTALGAGCTPAVDHQR
. : * : .
MSMEG_0082|M.smegmatis_MC2_155 MPGDH--VAVRWQGDYLIAVIELVPRPFTPTVIVNGSAMTDDVVNTKLVE
TH_1275|M.thermoresistible__bu APGDH--VAVRWQGDHLVSAIELVPRPFTPTVLVNGKAFTDDLLDTRLVE
Mflv_0756|M.gilvum_PYR-GCK VPGDH--VALRWQHGYLVSAIELIPRPFTPTVIVNGEAFTDDVIDSRQLE
Mvan_0091|M.vanbaalenii_PYR-1 IPGDH--VALRWQDDYLVSVIELVPRPFTPTVIVNGEAFTDDVVETRLVE
MLBr_00042|M.leprae_Br4923 KPADQ--VIMRWQDGFLVSVVELIPRPFTPTVIVDGEAQTDDLLETQLLE
MMAR_5458|M.marinum_M KPGDH--VAVRWRRDHLIAVIELKPRPFTPTVIVDGKAHTDDVLDTRLLE
Rv3885c|M.tuberculosis_H37Rv RSG----GGVRVQDGVAVVAVQLLGRAHRATTVTGSVTVESDNVIDVVEL
Mb3915c|M.bovis_AF2122/97 RSG----GGVRVQDGVAVVAVQLLGRAHRATTVTGSVTVESDNVIDVVEL
MAV_0159|M.avium_104 RSG----GGVRVQDGVAVVAVQLLGRAHRATLVTGSVTVETENVLDVVEL
MAB_3760|M.abscessus_ATCC_1997 PSGQDSWTGTRWENGKLITVLEISATQRHPSVITPDHCATDSLVPLRVLR
MUL_3078|M.ulcerans_Agy99 RFGRDT-VGVREHHGRLVTVITVDDGEGDAAGRHRHRTTQSAVVPVATVA
. * . . : .: : .: :
MSMEG_0082|M.smegmatis_MC2_155 RLLEAHCPDLEAD---VVSAGYRVGKTAPASLIALYEQ------VVGPYP
TH_1275|M.thermoresistible__bu QLLTAHCPDLEAD---IVSAGYRVGKTAPASLLALYEQ------VLGPYP
Mflv_0756|M.gilvum_PYR-GCK KLLAAYCPDLEAD---IVSAGYRVGRTAPAALVGLYEQ------VVGPYP
Mvan_0091|M.vanbaalenii_PYR-1 DLLTAYCPDLEAD---IVSAGYRVGKTAPAALVALYEQ------VVGPYP
MLBr_00042|M.leprae_Br4923 HLLSVHCPDLEAV---VVSAGYRVGHVASLDVVNLYQQ------VIGADP
MMAR_5458|M.marinum_M DLLSVHCPDLEAD---VVSAGYRVGNTASEEVVSLYQR------VIGADP
Rv3885c|M.tuberculosis_H37Rv APLLRHPLDLELDSISVVTFGSRTGTVG--DYPRVYDA------EIGTPP
Mb3915c|M.bovis_AF2122/97 APLPRHPLDLELDSISVVTFGSRTGTVG--DYPRVYDA------EIGTPP
MAV_0159|M.avium_104 APMLHQALGLQLDSISVVTVGSRHGNVG--DYPRVYDS------EIGTPP
MAB_3760|M.abscessus_ATCC_1997 ECMHQNDIELESID--VISNGQRTAQGT--VLRGGYDR------LVGPLP
MUL_3078|M.ulcerans_Agy99 ENLRQFDVQLDGVD--IMTVEVRGGAEAARASASLDEWGPEEWGMVGESP
: *: ::: * . : :* *
MSMEG_0082|M.smegmatis_MC2_155 APANRRTWIVLRADPEKTQRSAHRRD-SGVSGLARYLVASATRIADQLAS
TH_1275|M.thermoresistible__bu APANRRTWIVLRADPERTQKSARRRD-VGVAGLSRYLVASTTRIADQLAS
Mflv_0756|M.gilvum_PYR-GCK APARRRTWIVLRADPDKTRKSALRRD-VGVSGLAQYVVSSTTRIADHLAS
Mvan_0091|M.vanbaalenii_PYR-1 APASRRTWIVLRADPDKTRKSALRRN-EGVAGLAQYLVSSTTRIADHLAS
MLBr_00042|M.leprae_Br4923 APAHRRTWIMLRADPVRTRKSAQRRD-AGVAGLARYLIASTTRIADQLAS
MMAR_5458|M.marinum_M APANRRTWIMLRADPEQTRKSAQRRE-AGLAGLARYLVASATRIADGLAS
Rv3885c|M.tuberculosis_H37Rv YAGRRETWLIMRLPVIGNTQALRWRTSVGAAAISVAQRVASSLRCQGLRA
Mb3915c|M.bovis_AF2122/97 YAGRRETWLIMRLPVIGNTQALRWRTSVGAAAISVAQRVASSLRCQGLRA
MAV_0159|M.avium_104 YAGRRETWLIMRLAVIDNAQALRWRTTVGAAAISVAQRIAGLLRCQGLRA
MAB_3760|M.abscessus_ATCC_1997 AVAIRTVWVVLRFDPGANVDAVFRRG-GGRRGAERCAVIATARVRRALAA
MUL_3078|M.ulcerans_Agy99 AANRRRTWLILRMNPQRNVAAIASRD-----SLASTLVTATERLAQVLDG
* .*:::* . : * . : * .
MSMEG_0082|M.smegmatis_MC2_155 NGVDARCCRS------FDDYEKATEISYERETWSSIKGRSTFTAAYTAPG
TH_1275|M.thermoresistible__bu HGVDARCARS------FDDLDRATEISFERETWSSIKGRSTFTAAYSAPG
Mflv_0756|M.gilvum_PYR-GCK NGIDARPARS------FDDFDGATEISFERETWSMVKGRSTFTAAYHAPG
Mvan_0091|M.vanbaalenii_PYR-1 KGVDARPARS------FDDFDRATEISFERETWSMVKGRSTFTAAYHAPG
MLBr_00042|M.leprae_Br4923 HGVDAVCGHS------FESVDHATDVGFMQEKWSMMRGQNAYSVAYTAPA
MMAR_5458|M.marinum_M NGVDAVCGRS------FDDYDRATDIGYVREKWSMIKGADSYTAAYTAPG
Rv3885c|M.tuberculosis_H37Rv KLATATDLAE------LDRRLGSDAVAGSAQRWKAIRGEAGWMTTYAYPA
Mb3915c|M.bovis_AF2122/97 KLATATDLAE------LDRRLGSDAVAGSAQRWKAIRGEAGWMTTYAYPA
MAV_0159|M.avium_104 KVANATDLAE------LDRRLGWDAVSGTVQRWKAIRGEAGWMTTYAYPP
MAB_3760|M.abscessus_ATCC_1997 AHCASTILQAGQIHRISAEMLRQYAGAPMHEDWSGLTLIDSYNVAMGIDP
MUL_3078|M.ulcerans_Agy99 QSCAARPLAADELAEVDSTILAELAPTWSRPGWRHLKHFNGYATSFWVTP
: * : : .:
MSMEG_0082|M.smegmatis_MC2_155 GPD------MWWSARADHTITRVRVRPGAAPSSAI-----LLTTLA-NPT
TH_1275|M.thermoresistible__bu GPD------VWWSARADHTITRLRVRPGAPPTSTV-----LLTTLA-NPT
Mflv_0756|M.gilvum_PYR-GCK GPD------VWWSARADYTLTRVRIVPGAAPTATV-----LLTTLA-NPS
Mvan_0091|M.vanbaalenii_PYR-1 GPD------VWWSARADHTLTRMRIVPGSAPTTTV-----LLTTLA-NPS
MLBr_00042|M.leprae_Br4923 GPD------AWWSARADHTITRVRVAPGKTPQATV-----VLTTLG-KPK
MMAR_5458|M.marinum_M GPD------LWWSARADHTITRVRIAPGMPPRSTV-----LLTTVG-KPK
Rv3885c|M.tuberculosis_H37Rv EAISSRVLSQAWTLRADEVIQNVTVYPDATCTATI-----TVRTPTPAPT
Mb3915c|M.bovis_AF2122/97 EAISSRVLSQAWTLRADEVIQNVTVYPDATCTATI-----TVRTPTPAPT
MAV_0159|M.avium_104 QAITSRNLSQAWTLRADEVIQNVTVYPDGHCSATI-----TVRTPTPAPT
MAB_3760|M.abscessus_ATCC_1997 WYITDATLTGLWARPTLETSVTVRLRPAAKGRTSVGALVRWATDEQLPVR
MUL_3078|M.ulcerans_Agy99 ADIN------------AETLDEVWLSDAPEVGATV-----LTLRLVMRAG
. : : :::
MSMEG_0082|M.smegmatis_MC2_155 TPRGFSCLFGGQRAALQGIVPVSDKHYDLP-----------------IGS
TH_1275|M.thermoresistible__bu TPRGFSCLFGGQRAALEGLSPVTDKHHELP-----------------IGS
Mflv_0756|M.gilvum_PYR-GCK TPRGFSCLYGGQRAALLGESPVTDRHYELP-----------------IGS
Mvan_0091|M.vanbaalenii_PYR-1 TPRGFSCLFGGQRAALLGENPVTDRHYELP-----------------IGS
MLBr_00042|M.leprae_Br4923 TPCGFYRLHGAQQPALLGRSFVAYQHCQMP-----------------IGS
MMAR_5458|M.marinum_M TPRGFSRLFGSQRPALEGQTLVANHHCQLP-----------------IGS
Rv3885c|M.tuberculosis_H37Rv PPSVILRRLNGEQAAAAAANMCGPRPHLRGQRRCPLPAQLVT----EIGP
Mb3915c|M.bovis_AF2122/97 PPSVILRRLNGEQAAAAAANMCGPRPHLRGQRRCPLPAQLVT----EIGP
MAV_0159|M.avium_104 PPSVILRRLNGEQAAAAAANMCGPRPHLRGLRRSRLPAELIT----EIGP
MAB_3760|M.abscessus_ATCC_1997 HSTGMTSLNGSQRDAFFAGLPVGAIGLEYLTRSIEMSNEELDGIHLPTSG
MUL_3078|M.ulcerans_Agy99 EPRLSAWVRYHSDERLPKELSVG---------------------------
. .
MSMEG_0082|M.smegmatis_MC2_155 AGVLVGETADRYPVYMPFDNVDVS---INLGDARLFTQFVIRSAAAGAVV
TH_1275|M.thermoresistible__bu AGVLVGETVDRYPVYMPFDDVDVS---INLGDARLFTQFVVRSAAAGGVV
Mflv_0756|M.gilvum_PYR-GCK AGVLVGETADRYPVYMPFDDTDVS---INLGNARLFTQFVVRSAAAGANV
Mvan_0091|M.vanbaalenii_PYR-1 AGVLVGETADRYPVYMPFDDVDVS---INLGNARLFTQFVVRSAAAGAAV
MLBr_00042|M.leprae_Br4923 AGVLVGETVNRCSVYMPFDDVDVS---VSLGDVQTFTQFVVRAAAAGGIV
MMAR_5458|M.marinum_M AGVLIGETVNRRPVYMPFDDVDAT---VNLGDAQTFTQFAVRSAAAGGVV
Rv3885c|M.tuberculosis_H37Rv SGVLIGKLSNGDRLMIPVTDAGELSRVFVAADDTIAKRIVIRVVGAGERV
Mb3915c|M.bovis_AF2122/97 SGVLIGKLSNGDRLMIPVTDAGELSRVFVAADDTIAKRIVIRVVGAGERV
MAV_0159|M.avium_104 SGVLIGKLPNGDRLLMPVTDAGELSRVFVAADDPIAKRIVIRTAGAGERV
MAB_3760|M.abscessus_ATCC_1997 CGQLIGSDMSGRAIATRLSGQGVHT-VVVRAELYVCQQVVLRAVAIGALV
MUL_3078|M.ulcerans_Agy99 LNRLTGRQLAAVRASLPVP-------------------------STRAQL
. * * . . :
MSMEG_0082|M.smegmatis_MC2_155 TLGPQFREFATMINGRVGRTPRIGWPNATTYLGPHQ--------------
TH_1275|M.thermoresistible__bu TLLPQFREFASLINARVGPEAKISWPNATTYLGPHP--------------
Mflv_0756|M.gilvum_PYR-GCK TLQPQFGEFAGYVNAQIGPTAKVAWPHATTYLRPQP--------------
Mvan_0091|M.vanbaalenii_PYR-1 TLQPQFEEFAGFVNARIGQVAKVAWPHATTYLRPHP--------------
MLBr_00042|M.leprae_Br4923 TLGQQFEKFARMIGGQIGSVAKVAWPNATTYLDPYP--------------
MMAR_5458|M.marinum_M TVGPHFEQFAGLIGAHVGAEAKVVWPNATTYLGAHP--------------
Rv3885c|M.tuberculosis_H37Rv CVHTRDQERWASVRMPQLSIVGTPRPAPRTTVGVVEYVRRRKNGDDGKSE
Mb3915c|M.bovis_AF2122/97 CVHTRDQERWASVRMPQLSIVGTPRPAPRTTVGVVEYVRRRKNGDDGKSE
MAV_0159|M.avium_104 CVHTRDMSRWVSVRMPEISVVNSSRPAPRTTVSVVEYAPRR---------
MAB_3760|M.abscessus_ATCC_1997 VVYTDRPHMWDVMVTSIGDANRIQFASGPGFIDPRCTLAVVDGMQPTALP
MUL_3078|M.ulcerans_Agy99 VVSSRELLDHDELELPVGQTQEHATSATTGQ-------------------
: : .
MSMEG_0082|M.smegmatis_MC2_155 --GVGRVILRPNFIDTPRHRQLPIQLINPREESRYQMALEQ---------
TH_1275|M.thermoresistible__bu --GIGRVILRHNFIDTPRHRQLPIRLINPREESRYQMALEG---------
Mflv_0756|M.gilvum_PYR-GCK --GVGRVVLRDNFIATPRHKELPIRLINPREESRYQMALEP---------
Mvan_0091|M.vanbaalenii_PYR-1 --GVGRVMLRDDFIATPRHKQLPIRLINPREESRYQMVLEP---------
MLBr_00042|M.leprae_Br4923 --GSERVILKHDIIGTPRHRKLPIRRISPPEEGHYQMVLPKSSYEL----
MMAR_5458|M.marinum_M --GIDRVILRHNLVGTPRHRKLPIRRVSPPEESRFQMALPK---------
Rv3885c|M.tuberculosis_H37Rv GSGVDVAISPTPRPASVITIARPGTSLSESDRHGFEVTIEQIDRATVKVG
Mb3915c|M.bovis_AF2122/97 GSGVDVAISPTPRPASVITIARPGTSLSESDRHGFEVTIEQIDRATVKVG
MAV_0159|M.avium_104 GEGVEAAISPTPRPATVITVAPAGTTLSEAQRHGFEVIIEQVSPAVVNVS
MAB_3760|M.abscessus_ATCC_1997 SNCTALHIISSEYDALPARPDVIIDQPNGYGDHILLTAGGETIQVRLVTV
MUL_3078|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0082|M.smegmatis_MC2_155 -------------------------------
TH_1275|M.thermoresistible__bu -------------------------------
Mflv_0756|M.gilvum_PYR-GCK -------------------------------
Mvan_0091|M.vanbaalenii_PYR-1 -------------------------------
MLBr_00042|M.leprae_Br4923 -------------------------------
MMAR_5458|M.marinum_M -------------------------------
Rv3885c|M.tuberculosis_H37Rv AAGQNWLVEMEMFRAENRYVSLEPVTMSIGR
Mb3915c|M.bovis_AF2122/97 AAGQNWLVEMEMFRAENRYVSLEPVTMSIGR
MAV_0159|M.avium_104 AAGKNWLVEMDMFRAEHRYVSLEPVSMSVGM
MAB_3760|M.abscessus_ATCC_1997 SDELAYLGRPIQAFAQ---------------
MUL_3078|M.ulcerans_Agy99 -------------------------------