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AYDVARVRGLHPSLGDGWVHFDAPAGMLIPDSVATTVSTAFRRSGASTVGAHPSARRSAAVLDAAREAVA DLVNADPGGVVLGADRAVLLSLLAEASSSRAGLGYEVIVSRLDDEANIAPWLRAAHRYGAKVKWAEVDIE TGELPTWQWESLISKSTRLVAVNSASGTLGGVTDLRAMTKLVHDVGALVVVDHSAAAPYRLLDIRETDAD VVTVNAHAWGGPPIGAMVFRDPSVMNSFGSVSTNPYATGPARLEIGVHQFGLLAGVVASIEYLAALDESA RGSRRERLAVSMQSADAYLNRVFDYLMVSLRSLPLVMLIGRPEAQIPVVSFAVHKVPADRVVQRLADNGI LAIANTGSRVLDVLGVNDVGGAVTVGLAHYSTMAEVDQLVRALASLG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3778c | - | - | 100% (398) | POSSIBLE AMINOTRANSFERASE |
| M. tuberculosis H37Rv | Rv1464 | csd | 3e-17 | 25.48% (365) | cysteine desulfurase |
| M. tuberculosis H37Rv | Rv3025c | iscS | 8e-06 | 22.66% (203) | cysteine desulfurase IscS |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3807c | - | 0.0 | 100.00% (398) | aminotransferase |
| M. gilvum PYR-GCK | Mflv_1188 | - | 1e-175 | 77.14% (398) | cysteine desulfurase family protein |
| M. leprae Br4923 | MLBr_00117 | - | 0.0 | 83.42% (398) | hypothetical protein MLBr_00117 |
| M. abscessus ATCC 19977 | MAB_0206 | - | 1e-164 | 71.36% (398) | aminotransferase/cysteine desulfurase |
| M. marinum M | MMAR_5333 | - | 0.0 | 89.45% (398) | aminotransferase |
| M. avium 104 | MAV_0241 | - | 0.0 | 87.44% (398) | cysteine desulfurase family protein |
| M. smegmatis MC2 155 | MSMEG_6363 | - | 0.0 | 79.40% (398) | cysteine desulfurase family protein |
| M. thermoresistible (build 8) | TH_1666 | - | 0.0 | 78.34% (397) | POSSIBLE AMINOTRANSFERASE |
| M. ulcerans Agy99 | MUL_0095 | - | 0.0 | 89.45% (398) | aminotransferase |
| M. vanbaalenii PYR-1 | Mvan_5616 | - | 1e-178 | 77.64% (398) | cysteine desulfurase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1188|M.gilvum_PYR-GCK MAFDVARVRGLHPSLGDGWVHMDAQNGMLLPDSVGRAVSTAFRGSMPTTS
Mvan_5616|M.vanbaalenii_PYR-1 MAYDVARVRGLHPSLGDGWVHMDAQNGMLLPDSVGRAVSTAFRGSMPTTS
MSMEG_6363|M.smegmatis_MC2_155 MAYDVARVRGLHPTLGDGWVHFDAQSGMLVPDAVATTVSTAFRGSMPSAL
Rv3778c|M.tuberculosis_H37Rv MAYDVARVRGLHPSLGDGWVHFDAPAGMLIPDSVATTVSTAFRRSGASTV
Mb3807c|M.bovis_AF2122/97 MAYDVARVRGLHPSLGDGWVHFDAPAGMLIPDSVATTVSTAFRRSGASTV
MMAR_5333|M.marinum_M MAYDVARVRGLHPSLGDGWVHFDAPAGMLIPDSVATTVSTAFRRSAASTA
MUL_0095|M.ulcerans_Agy99 MAYDVARVRGLHPSLGDGWVHFDAPAGMLIPDSVATTVSTAFRRSAASTA
MAV_0241|M.avium_104 MAYDVARVRGLHPSLGDGWVHFDAPAGMLIPDSVATTVSTAFRRSGPTTV
MLBr_00117|M.leprae_Br4923 MAYDAARVRGLHPSLGDGWVHFDAPAGMLIPDSVATTVSTAFRRSSSTTS
TH_1666|M.thermoresistible__bu MAYDVARVRGLHPSLGGGWVHFDAQNGMLLPDAVATSVSTAFRGSMSTTA
MAB_0206|M.abscessus_ATCC_1997 MAYDVARVRGLHPTLGDGWVHFDTQAGMLIPDAVATTVSTAFRGSFSDTR
**:*.********:**.****:*: ***:**:*. :****** * . :
Mflv_1188|M.gilvum_PYR-GCK SAHPAARRSAAVLAAARQAVADLVNADPAGVVLGADRAVLLTSLADAASG
Mvan_5616|M.vanbaalenii_PYR-1 SAHPAARRSAAVLAAARQAVADLVNADPAGVVLGADRAVLLTSLADAASG
MSMEG_6363|M.smegmatis_MC2_155 GPHPSARRSAAVLAAARQAVADLVNADPRGVVLGPDRAHLLTSLAEASSA
Rv3778c|M.tuberculosis_H37Rv GAHPSARRSAAVLDAAREAVADLVNADPGGVVLGADRAVLLSLLAEASSS
Mb3807c|M.bovis_AF2122/97 GAHPSARRSAAVLDAAREAVADLVNADPGGVVLGADRAVLLSLLAEASSS
MMAR_5333|M.marinum_M GAHPSARRSAAVLQTAREAVADLVNADPAGVVLGADRAVLLSALAEASSS
MUL_0095|M.ulcerans_Agy99 GAHPSARRSAAVLQTAREAVADLVNADPAGVVLGADRAVLLSALAEASSS
MAV_0241|M.avium_104 GAHPSAQRSAAILEAARAAVADLFNAEPAGVVLGADRAILLSALAEASSS
MLBr_00117|M.leprae_Br4923 GAHPSAQRSAAVLAAARASVADLFGADPAGVVLAADRAVLLSSLAAASSS
TH_1666|M.thermoresistible__bu GPHPSARRSAAVLHAARQAIADFVNADPRGVVLGADRAILLSLLADAASS
MAB_0206|M.abscessus_ATCC_1997 GPHPSARRSAAVLEAARHAAADLVGADARGVVLGSDRAILLNSLAEGSSS
..**:*:****:* :** : **:..*:. ****..*** **. ** .:*.
Mflv_1188|M.gilvum_PYR-GCK RVGLGYEVVVTRLDDEANIAPWLRAADLFGAQVKWAEVDIETGELPTWQW
Mvan_5616|M.vanbaalenii_PYR-1 RVGLGYELVVSRLDDEANIAPWLRAANRFGAKVKWAEVDIETGELPTWQW
MSMEG_6363|M.smegmatis_MC2_155 RVGLGYEVVVTRLDDEANIAPWLRAANRYGAKVKWAEVDIETGELPSWQW
Rv3778c|M.tuberculosis_H37Rv RAGLGYEVIVSRLDDEANIAPWLRAAHRYGAKVKWAEVDIETGELPTWQW
Mb3807c|M.bovis_AF2122/97 RAGLGYEVIVSRLDDEANIAPWLRAAHRYGAKVKWAEVDIETGELPTWQW
MMAR_5333|M.marinum_M RAGLGYEVIVSRLDDEANIAPWLRAAHRYGAKVKWAEVDIETGELPTWQW
MUL_0095|M.ulcerans_Agy99 RAGLGYEVIVSRLDDEANIAPWLRAAHRYGAKVKWAEVDIETGELPTWQW
MAV_0241|M.avium_104 RAGLGYEVIVSRLDDEANIAPWLRAAHRYGAKVKWAEIDIETGELPTWQW
MLBr_00117|M.leprae_Br4923 CAGLGYEVIVSRLDDEVNIAPWLRAAHRHGAKVKWAEVDIETGELPTWQW
TH_1666|M.thermoresistible__bu RVGLGYEVVVSRLDDEANIAPWLRAANRYGAKVRWAEVDIETGELPAWQW
MAB_0206|M.abscessus_ATCC_1997 KAGLGYELVVSRLDEEANVQPWLRSANRYGAKVKWAEVDIESGDLPSWQW
.*****::*:***:*.*: ****:*. .**:*:***:***:*:**:***
Mflv_1188|M.gilvum_PYR-GCK ESLVSRPTRIVAIASASATLGAVTELREVTKLVHEVNGLVIVDHSAAAPY
Mvan_5616|M.vanbaalenii_PYR-1 EGLVTRPTRLVAITSASSTLGTVTELREVTKLVHEVGGLVIVDHSAAAPY
MSMEG_6363|M.smegmatis_MC2_155 EGLIDKPTRLVAIASASSTLGTVTDLREVTKLTHEVGGLVVVDHSAAAPY
Rv3778c|M.tuberculosis_H37Rv ESLISKSTRLVAVNSASGTLGGVTDLRAMTKLVHDVGALVVVDHSAAAPY
Mb3807c|M.bovis_AF2122/97 ESLISKSTRLVAVNSASGTLGGVTDLRAMTKLVHDVGALVVVDHSAAAPY
MMAR_5333|M.marinum_M ESLISKSTRLVAVTSASGTLGAVTDLRAMTKLVHDIGGLVVVDHSAAAPY
MUL_0095|M.ulcerans_Agy99 ESLISKSTRLVAVTSASGTLGAVTDLRAMTKLVHDIGGLVVVDHSAAAPY
MAV_0241|M.avium_104 EGLIGKSTRLVAVASASATLGTVTDLRAMTKLVHDVGGLVVVDHSAAAPY
MLBr_00117|M.leprae_Br4923 ESLIGESTRLVAVTSASGTLGTVTDLRAMTKLVHDVGGLVVVDHSAASPY
TH_1666|M.thermoresistible__bu ESLIGRSTRLVAVSSASSTLGTITDLQLMTKLVHDVGGLVVLDHSAAAPY
MAB_0206|M.abscessus_ATCC_1997 ESLITKPTRLVAVTAASSTLGTVPDLQQATKLAHAVGGLVVMDCSSLVPY
*.*: ..**:**: :**.*** :.:*: ***.* :..**::* *: **
Mflv_1188|M.gilvum_PYR-GCK RLIDINEIDADVVAVNALAWGGPPIGALVFRDPSLISAFGSVSLDPTATG
Mvan_5616|M.vanbaalenii_PYR-1 RLIDIDEIDADVVALNALAWGGPPIGALVFRDPAVIDAFGSVSLDPHASG
MSMEG_6363|M.smegmatis_MC2_155 RLIDVNEIEADVVALNAVGWGGPPIGALVFRDPALIDSFGSVSLNPYATG
Rv3778c|M.tuberculosis_H37Rv RLLDIRETDADVVTVNAHAWGGPPIGAMVFRDPSVMNSFGSVSTNPYATG
Mb3807c|M.bovis_AF2122/97 RLLDIRETDADVVTVNAHAWGGPPIGAMVFRDPSVMNSFGSVSTNPYATG
MMAR_5333|M.marinum_M RLFDIKETEADVVAMNAVGWGGPPIGAMVFREPALMHSFSSVSTDPHATG
MUL_0095|M.ulcerans_Agy99 RLFDIKETEADVVAMNAVGWGGPPIGAMVFREPALMHSFSSVSTDPHATG
MAV_0241|M.avium_104 RLLDVKETDADVVAVNAAAWGGPPIGAMVFRDPALLNSFSSISADPKATG
MLBr_00117|M.leprae_Br4923 RLLDLNETEVDVVAVNAHAWGGPPIGAVVFRDPGLIDTFTLASTDPHAAG
TH_1666|M.thermoresistible__bu RLIDIDDLDADVIALNAVAWGGPPIGALVFRDPAIIDSFSSMSLNPFATG
MAB_0206|M.abscessus_ATCC_1997 RAFDIEDLDADVIAFNATAWGGPPVGALVFRDPALLDSISSISLNPLASG
* :*: : :.**::.** .*****:**:***:*.:: :: * :* *:*
Mflv_1188|M.gilvum_PYR-GCK AARLELGAHQFGMLAGVVASIEYLATLDDSAQGSRRERLAVSMRSASAYL
Mvan_5616|M.vanbaalenii_PYR-1 AARLELGSHQFGMLAGVVASVEYLAGLDDSAQGTRRERLSISMRSASAYM
MSMEG_6363|M.smegmatis_MC2_155 PARLELGVHQYGLLAGVVASIEYLSNLDEAASGTRRERLEISMQSAGVYL
Rv3778c|M.tuberculosis_H37Rv PARLEIGVHQFGLLAGVVASIEYLAALDESARGSRRERLAVSMQSADAYL
Mb3807c|M.bovis_AF2122/97 PARLEIGVHQFGLLAGVVASIEYLAALDESARGSRRERLAVSMQSADAYL
MMAR_5333|M.marinum_M PERLETGLHQFGFLAGVVASIEYLASLDESARGTRRERLSVSMQSASAYL
MUL_0095|M.ulcerans_Agy99 PERLETGLHQFGFLAGVVASIEYLASLDESARGTRRERLSVSMQSASAYL
MAV_0241|M.avium_104 AARLEIGAHQFGLLAGVVASIEYLASLDESARGTRRERLAVSMQSATSYL
MLBr_00117|M.leprae_Br4923 PARLEVGLHQFGLLAGVVDSIEYLAALDESARGSRRERLSVSMQSAGLYL
TH_1666|M.thermoresistible__bu PARLELGLHQFGLLGGVVASIEYLAGLDESATGSRRERLAISMESANAYV
MAB_0206|M.abscessus_ATCC_1997 PARLELGGHQFAMLAGLVASVEYLAGLDESASGTRRERLLTSLNSAGAYL
. *** * **:.:*.*:* *:***: **::* *:***** *:.** *:
Mflv_1188|M.gilvum_PYR-GCK SALFDYLLTSLRSLPTLTVIGSPEVRIPVLTFAIDNVSAERVVQRLADNG
Mvan_5616|M.vanbaalenii_PYR-1 NALFDYLLVSLRSLPTVTVIGSPEVRIPVLSFAIDNVPAERVVQRLADNG
MSMEG_6363|M.smegmatis_MC2_155 SRLFDYLQTSLRSLPLVMVIGSPETSIPVLSFAVRDVPAERVVQRLADNG
Rv3778c|M.tuberculosis_H37Rv NRVFDYLMVSLRSLPLVMLIGRPEAQIPVVSFAVHKVPADRVVQRLADNG
Mb3807c|M.bovis_AF2122/97 NRVFDYLMVSLRSLPLVMLIGRPEAQIPVVSFAVHKVPADRVVQRLADNG
MMAR_5333|M.marinum_M NRIFDYLMVSLRSLPLVMLIGRPEARIPVVSFALQDVPADRVVQRLADNG
MUL_0095|M.ulcerans_Agy99 NRIFDYLMVSLRSLPLVMLIGRPEARIPVVSFALQDVPADRVVQRLADNG
MAV_0241|M.avium_104 NRIYDYLMVSLRSLPLVMVIGRPEVRIPVVSFALHGVPAERVVQRLADNG
MLBr_00117|M.leprae_Br4923 NRIFDYLMMSLRSLSLVMVIGRPEVRIPVVSFVHQGVPADMVVQRLADNG
TH_1666|M.thermoresistible__bu DRVFDYLLASLQSLPRVMVIGNPESRIPALSFAVHDVTAERVVQHLADHG
MAB_0206|M.abscessus_ATCC_1997 DWLFRYLVSALRTLPRVMVIGAPEDRIPALSFTVIGVPADRVVQRLADNG
. :: ** :*::*. : :** ** **.::*. *.*: ***:***:*
Mflv_1188|M.gilvum_PYR-GCK ILAIANANSRVLDVIGVNDVGGAVTIGLAHYSTAAEVDQLVRALASLG
Mvan_5616|M.vanbaalenii_PYR-1 ILAIANASSRVLDVIGVNDVGGAVTVGLAHYSTSAEVDQLVRALASLG
MSMEG_6363|M.smegmatis_MC2_155 VLAIANASSRVLDVIGVNDIGGAVTIGLSHYSTTAEVDQLVRALASLG
Rv3778c|M.tuberculosis_H37Rv ILAIANTGSRVLDVLGVNDVGGAVTVGLAHYSTMAEVDQLVRALASLG
Mb3807c|M.bovis_AF2122/97 ILAIANTGSRVLDVLGVNDVGGAVTVGLAHYSTMAEVDQLVRALASLG
MMAR_5333|M.marinum_M ILAVSNSSSRVFDVLGVNDVGGAVTVGLAHYSTMAEVDQLVRALASLG
MUL_0095|M.ulcerans_Agy99 ILAVSNSSSRVFDVLGVNDVGGAVTVGLAHYSTMAEVDQLVRALASLG
MAV_0241|M.avium_104 ILAVTNESSRALDVLGVNDVGGAVTVGLAHYSTTAEVDQLVRALASLG
MLBr_00117|M.leprae_Br4923 ILAICDPRSRVLDVLGVNDIGGAVTVGLAHYSTTVEVDQLVRTLASLG
TH_1666|M.thermoresistible__bu ILAIANTSSRVLDVIGVNDIGGAVTLGLGHYTTTAEVDQLIRALAALV
MAB_0206|M.abscessus_ATCC_1997 VCAIANTSSRVLDAIGVNEIGGAITVGLGHYSTAAEVDQLVRAVASLG
: *: : **.:*.:***::***:*:**.**:* .*****:*::*:*