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M. abscessus ATCC 19977 MAB_0206 (-)

annotation: aminotransferase/cysteine desulfurase
coordinates: 216223 - 217419
length: 398

MAYDVARVRGLHPTLGDGWVHFDTQAGMLIPDAVATTVSTAFRGSFSDTRGPHPSARRSAAVLEAARHAA
ADLVGADARGVVLGSDRAILLNSLAEGSSSKAGLGYELVVSRLDEEANVQPWLRSANRYGAKVKWAEVDI
ESGDLPSWQWESLITKPTRLVAVTAASSTLGTVPDLQQATKLAHAVGGLVVMDCSSLVPYRAFDIEDLDA
DVIAFNATAWGGPPVGALVFRDPALLDSISSISLNPLASGPARLELGGHQFAMLAGLVASVEYLAGLDES
ASGTRRERLLTSLNSAGAYLDWLFRYLVSALRTLPRVMVIGAPEDRIPALSFTVIGVPADRVVQRLADNG
VCAIANTSSRVLDAIGVNEIGGAITVGLGHYSTAAEVDQLVRAVASLG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_0206--100% (398)aminotransferase/cysteine desulfurase
M. abscessus ATCC 19977MAB_0217c-1e-2927.45% (419) cysteine desulfurase
M. abscessus ATCC 19977MAB_2746c-2e-2427.52% (327) cysteine desulfurase/aminotransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3807c-1e-16471.36% (398) aminotransferase
M. gilvum PYR-GCKMflv_1188-1e-15866.83% (398) cysteine desulfurase family protein
M. tuberculosis H37RvRv3778c-1e-16471.36% (398) aminotransferase
M. leprae Br4923MLBr_00117-1e-15668.59% (398) hypothetical protein MLBr_00117
M. marinum MMMAR_5333-1e-16470.85% (398) aminotransferase
M. avium 104MAV_0241-1e-16370.85% (398) cysteine desulfurase family protein
M. smegmatis MC2 155MSMEG_6363-1e-17274.62% (398) cysteine desulfurase family protein
M. thermoresistible (build 8)TH_1666-1e-17174.31% (397) POSSIBLE AMINOTRANSFERASE
M. ulcerans Agy99MUL_0095-1e-16470.85% (398) aminotransferase
M. vanbaalenii PYR-1Mvan_5616-1e-16771.61% (398) cysteine desulfurase family protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb3807c|M.bovis_AF2122/97           MAYDVARVRGLHPSLGDGWVHFDAPAGMLIPDSVATTVSTAFRRSGASTV
Rv3778c|M.tuberculosis_H37Rv        MAYDVARVRGLHPSLGDGWVHFDAPAGMLIPDSVATTVSTAFRRSGASTV
MMAR_5333|M.marinum_M               MAYDVARVRGLHPSLGDGWVHFDAPAGMLIPDSVATTVSTAFRRSAASTA
MUL_0095|M.ulcerans_Agy99           MAYDVARVRGLHPSLGDGWVHFDAPAGMLIPDSVATTVSTAFRRSAASTA
MAV_0241|M.avium_104                MAYDVARVRGLHPSLGDGWVHFDAPAGMLIPDSVATTVSTAFRRSGPTTV
MLBr_00117|M.leprae_Br4923          MAYDAARVRGLHPSLGDGWVHFDAPAGMLIPDSVATTVSTAFRRSSSTTS
Mflv_1188|M.gilvum_PYR-GCK          MAFDVARVRGLHPSLGDGWVHMDAQNGMLLPDSVGRAVSTAFRGSMPTTS
Mvan_5616|M.vanbaalenii_PYR-1       MAYDVARVRGLHPSLGDGWVHMDAQNGMLLPDSVGRAVSTAFRGSMPTTS
MSMEG_6363|M.smegmatis_MC2_155      MAYDVARVRGLHPTLGDGWVHFDAQSGMLVPDAVATTVSTAFRGSMPSAL
TH_1666|M.thermoresistible__bu      MAYDVARVRGLHPSLGGGWVHFDAQNGMLLPDAVATSVSTAFRGSMSTTA
MAB_0206|M.abscessus_ATCC_1997      MAYDVARVRGLHPTLGDGWVHFDTQAGMLIPDAVATTVSTAFRGSFSDTR
                                    **:*.********:**.****:*:  ***:**:*. :****** * . : 

Mb3807c|M.bovis_AF2122/97           GAHPSARRSAAVLDAAREAVADLVNADPGGVVLGADRAVLLSLLAEASSS
Rv3778c|M.tuberculosis_H37Rv        GAHPSARRSAAVLDAAREAVADLVNADPGGVVLGADRAVLLSLLAEASSS
MMAR_5333|M.marinum_M               GAHPSARRSAAVLQTAREAVADLVNADPAGVVLGADRAVLLSALAEASSS
MUL_0095|M.ulcerans_Agy99           GAHPSARRSAAVLQTAREAVADLVNADPAGVVLGADRAVLLSALAEASSS
MAV_0241|M.avium_104                GAHPSAQRSAAILEAARAAVADLFNAEPAGVVLGADRAILLSALAEASSS
MLBr_00117|M.leprae_Br4923          GAHPSAQRSAAVLAAARASVADLFGADPAGVVLAADRAVLLSSLAAASSS
Mflv_1188|M.gilvum_PYR-GCK          SAHPAARRSAAVLAAARQAVADLVNADPAGVVLGADRAVLLTSLADAASG
Mvan_5616|M.vanbaalenii_PYR-1       SAHPAARRSAAVLAAARQAVADLVNADPAGVVLGADRAVLLTSLADAASG
MSMEG_6363|M.smegmatis_MC2_155      GPHPSARRSAAVLAAARQAVADLVNADPRGVVLGPDRAHLLTSLAEASSA
TH_1666|M.thermoresistible__bu      GPHPSARRSAAVLHAARQAIADFVNADPRGVVLGADRAILLSLLADAASS
MAB_0206|M.abscessus_ATCC_1997      GPHPSARRSAAVLEAARHAAADLVGADARGVVLGSDRAILLNSLAEGSSS
                                    ..**:*:****:* :** : **:..*:. ****..*** **. ** .:*.

Mb3807c|M.bovis_AF2122/97           RAGLGYEVIVSRLDDEANIAPWLRAAHRYGAKVKWAEVDIETGELPTWQW
Rv3778c|M.tuberculosis_H37Rv        RAGLGYEVIVSRLDDEANIAPWLRAAHRYGAKVKWAEVDIETGELPTWQW
MMAR_5333|M.marinum_M               RAGLGYEVIVSRLDDEANIAPWLRAAHRYGAKVKWAEVDIETGELPTWQW
MUL_0095|M.ulcerans_Agy99           RAGLGYEVIVSRLDDEANIAPWLRAAHRYGAKVKWAEVDIETGELPTWQW
MAV_0241|M.avium_104                RAGLGYEVIVSRLDDEANIAPWLRAAHRYGAKVKWAEIDIETGELPTWQW
MLBr_00117|M.leprae_Br4923          CAGLGYEVIVSRLDDEVNIAPWLRAAHRHGAKVKWAEVDIETGELPTWQW
Mflv_1188|M.gilvum_PYR-GCK          RVGLGYEVVVTRLDDEANIAPWLRAADLFGAQVKWAEVDIETGELPTWQW
Mvan_5616|M.vanbaalenii_PYR-1       RVGLGYELVVSRLDDEANIAPWLRAANRFGAKVKWAEVDIETGELPTWQW
MSMEG_6363|M.smegmatis_MC2_155      RVGLGYEVVVTRLDDEANIAPWLRAANRYGAKVKWAEVDIETGELPSWQW
TH_1666|M.thermoresistible__bu      RVGLGYEVVVSRLDDEANIAPWLRAANRYGAKVRWAEVDIETGELPAWQW
MAB_0206|M.abscessus_ATCC_1997      KAGLGYELVVSRLDEEANVQPWLRSANRYGAKVKWAEVDIESGDLPSWQW
                                     .*****::*:***:*.*: ****:*. .**:*:***:***:*:**:***

Mb3807c|M.bovis_AF2122/97           ESLISKSTRLVAVNSASGTLGGVTDLRAMTKLVHDVGALVVVDHSAAAPY
Rv3778c|M.tuberculosis_H37Rv        ESLISKSTRLVAVNSASGTLGGVTDLRAMTKLVHDVGALVVVDHSAAAPY
MMAR_5333|M.marinum_M               ESLISKSTRLVAVTSASGTLGAVTDLRAMTKLVHDIGGLVVVDHSAAAPY
MUL_0095|M.ulcerans_Agy99           ESLISKSTRLVAVTSASGTLGAVTDLRAMTKLVHDIGGLVVVDHSAAAPY
MAV_0241|M.avium_104                EGLIGKSTRLVAVASASATLGTVTDLRAMTKLVHDVGGLVVVDHSAAAPY
MLBr_00117|M.leprae_Br4923          ESLIGESTRLVAVTSASGTLGTVTDLRAMTKLVHDVGGLVVVDHSAASPY
Mflv_1188|M.gilvum_PYR-GCK          ESLVSRPTRIVAIASASATLGAVTELREVTKLVHEVNGLVIVDHSAAAPY
Mvan_5616|M.vanbaalenii_PYR-1       EGLVTRPTRLVAITSASSTLGTVTELREVTKLVHEVGGLVIVDHSAAAPY
MSMEG_6363|M.smegmatis_MC2_155      EGLIDKPTRLVAIASASSTLGTVTDLREVTKLTHEVGGLVVVDHSAAAPY
TH_1666|M.thermoresistible__bu      ESLIGRSTRLVAVSSASSTLGTITDLQLMTKLVHDVGGLVVLDHSAAAPY
MAB_0206|M.abscessus_ATCC_1997      ESLITKPTRLVAVTAASSTLGTVPDLQQATKLAHAVGGLVVMDCSSLVPY
                                    *.*: ..**:**: :**.*** :.:*:  ***.* :..**::* *:  **

Mb3807c|M.bovis_AF2122/97           RLLDIRETDADVVTVNAHAWGGPPIGAMVFRDPSVMNSFGSVSTNPYATG
Rv3778c|M.tuberculosis_H37Rv        RLLDIRETDADVVTVNAHAWGGPPIGAMVFRDPSVMNSFGSVSTNPYATG
MMAR_5333|M.marinum_M               RLFDIKETEADVVAMNAVGWGGPPIGAMVFREPALMHSFSSVSTDPHATG
MUL_0095|M.ulcerans_Agy99           RLFDIKETEADVVAMNAVGWGGPPIGAMVFREPALMHSFSSVSTDPHATG
MAV_0241|M.avium_104                RLLDVKETDADVVAVNAAAWGGPPIGAMVFRDPALLNSFSSISADPKATG
MLBr_00117|M.leprae_Br4923          RLLDLNETEVDVVAVNAHAWGGPPIGAVVFRDPGLIDTFTLASTDPHAAG
Mflv_1188|M.gilvum_PYR-GCK          RLIDINEIDADVVAVNALAWGGPPIGALVFRDPSLISAFGSVSLDPTATG
Mvan_5616|M.vanbaalenii_PYR-1       RLIDIDEIDADVVALNALAWGGPPIGALVFRDPAVIDAFGSVSLDPHASG
MSMEG_6363|M.smegmatis_MC2_155      RLIDVNEIEADVVALNAVGWGGPPIGALVFRDPALIDSFGSVSLNPYATG
TH_1666|M.thermoresistible__bu      RLIDIDDLDADVIALNAVAWGGPPIGALVFRDPAIIDSFSSMSLNPFATG
MAB_0206|M.abscessus_ATCC_1997      RAFDIEDLDADVIAFNATAWGGPPVGALVFRDPALLDSISSISLNPLASG
                                    * :*: : :.**::.** .*****:**:***:*.:: ::   * :* *:*

Mb3807c|M.bovis_AF2122/97           PARLEIGVHQFGLLAGVVASIEYLAALDESARGSRRERLAVSMQSADAYL
Rv3778c|M.tuberculosis_H37Rv        PARLEIGVHQFGLLAGVVASIEYLAALDESARGSRRERLAVSMQSADAYL
MMAR_5333|M.marinum_M               PERLETGLHQFGFLAGVVASIEYLASLDESARGTRRERLSVSMQSASAYL
MUL_0095|M.ulcerans_Agy99           PERLETGLHQFGFLAGVVASIEYLASLDESARGTRRERLSVSMQSASAYL
MAV_0241|M.avium_104                AARLEIGAHQFGLLAGVVASIEYLASLDESARGTRRERLAVSMQSATSYL
MLBr_00117|M.leprae_Br4923          PARLEVGLHQFGLLAGVVDSIEYLAALDESARGSRRERLSVSMQSAGLYL
Mflv_1188|M.gilvum_PYR-GCK          AARLELGAHQFGMLAGVVASIEYLATLDDSAQGSRRERLAVSMRSASAYL
Mvan_5616|M.vanbaalenii_PYR-1       AARLELGSHQFGMLAGVVASVEYLAGLDDSAQGTRRERLSISMRSASAYM
MSMEG_6363|M.smegmatis_MC2_155      PARLELGVHQYGLLAGVVASIEYLSNLDEAASGTRRERLEISMQSAGVYL
TH_1666|M.thermoresistible__bu      PARLELGLHQFGLLGGVVASIEYLAGLDESATGSRRERLAISMESANAYV
MAB_0206|M.abscessus_ATCC_1997      PARLELGGHQFAMLAGLVASVEYLAGLDESASGTRRERLLTSLNSAGAYL
                                    . *** * **:.:*.*:* *:***: **::* *:*****  *:.**  *:

Mb3807c|M.bovis_AF2122/97           NRVFDYLMVSLRSLPLVMLIGRPEAQIPVVSFAVHKVPADRVVQRLADNG
Rv3778c|M.tuberculosis_H37Rv        NRVFDYLMVSLRSLPLVMLIGRPEAQIPVVSFAVHKVPADRVVQRLADNG
MMAR_5333|M.marinum_M               NRIFDYLMVSLRSLPLVMLIGRPEARIPVVSFALQDVPADRVVQRLADNG
MUL_0095|M.ulcerans_Agy99           NRIFDYLMVSLRSLPLVMLIGRPEARIPVVSFALQDVPADRVVQRLADNG
MAV_0241|M.avium_104                NRIYDYLMVSLRSLPLVMVIGRPEVRIPVVSFALHGVPAERVVQRLADNG
MLBr_00117|M.leprae_Br4923          NRIFDYLMMSLRSLSLVMVIGRPEVRIPVVSFVHQGVPADMVVQRLADNG
Mflv_1188|M.gilvum_PYR-GCK          SALFDYLLTSLRSLPTLTVIGSPEVRIPVLTFAIDNVSAERVVQRLADNG
Mvan_5616|M.vanbaalenii_PYR-1       NALFDYLLVSLRSLPTVTVIGSPEVRIPVLSFAIDNVPAERVVQRLADNG
MSMEG_6363|M.smegmatis_MC2_155      SRLFDYLQTSLRSLPLVMVIGSPETSIPVLSFAVRDVPAERVVQRLADNG
TH_1666|M.thermoresistible__bu      DRVFDYLLASLQSLPRVMVIGNPESRIPALSFAVHDVTAERVVQHLADHG
MAB_0206|M.abscessus_ATCC_1997      DWLFRYLVSALRTLPRVMVIGAPEDRIPALSFTVIGVPADRVVQRLADNG
                                    . :: **  :*::*. : :** **  **.::*.   *.*: ***:***:*

Mb3807c|M.bovis_AF2122/97           ILAIANTGSRVLDVLGVNDVGGAVTVGLAHYSTMAEVDQLVRALASLG
Rv3778c|M.tuberculosis_H37Rv        ILAIANTGSRVLDVLGVNDVGGAVTVGLAHYSTMAEVDQLVRALASLG
MMAR_5333|M.marinum_M               ILAVSNSSSRVFDVLGVNDVGGAVTVGLAHYSTMAEVDQLVRALASLG
MUL_0095|M.ulcerans_Agy99           ILAVSNSSSRVFDVLGVNDVGGAVTVGLAHYSTMAEVDQLVRALASLG
MAV_0241|M.avium_104                ILAVTNESSRALDVLGVNDVGGAVTVGLAHYSTTAEVDQLVRALASLG
MLBr_00117|M.leprae_Br4923          ILAICDPRSRVLDVLGVNDIGGAVTVGLAHYSTTVEVDQLVRTLASLG
Mflv_1188|M.gilvum_PYR-GCK          ILAIANANSRVLDVIGVNDVGGAVTIGLAHYSTAAEVDQLVRALASLG
Mvan_5616|M.vanbaalenii_PYR-1       ILAIANASSRVLDVIGVNDVGGAVTVGLAHYSTSAEVDQLVRALASLG
MSMEG_6363|M.smegmatis_MC2_155      VLAIANASSRVLDVIGVNDIGGAVTIGLSHYSTTAEVDQLVRALASLG
TH_1666|M.thermoresistible__bu      ILAIANTSSRVLDVIGVNDIGGAVTLGLGHYTTTAEVDQLIRALAALV
MAB_0206|M.abscessus_ATCC_1997      VCAIANTSSRVLDAIGVNEIGGAITVGLGHYSTAAEVDQLVRAVASLG
                                    : *: :  **.:*.:***::***:*:**.**:* .*****:*::*:*