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QTAHRRFAAAFAAVLLAVVCLPANTAAADDKLPLGGGAGIVVNGDTMCTLTTIGHDKNGDLIGFTSAHCG GPGAQIAAEGAENAGPVGIMVAGNDGLDYAVIKFDPAKVTPVAVFNGFAINGIGPDPSFGQIACKQGRTT GNSCGVTWGPGESPGTLVMQVCGGPGDSGAPVTVDNLLVGMIHGAFSDNLPSCITKYIPLHTPAVVMSIN ADLADINAKNRPGAGFVPVPA*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv3668c | - | - | 100% (232) | POSSIBLE PROTEASE |
M. tuberculosis H37Rv | Rv1815 | - | 2e-05 | 30.56% (180) | hypothetical protein Rv1815 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3692c | - | 1e-136 | 100.00% (232) | putative protease |
M. gilvum PYR-GCK | Mflv_1379 | - | 4e-89 | 73.00% (200) | peptidase S1 and S6, chymotrypsin/Hap |
M. leprae Br4923 | MLBr_02295 | - | 1e-106 | 77.49% (231) | hypothetical protein MLBr_02295 |
M. abscessus ATCC 19977 | MAB_0424 | - | 9e-79 | 62.61% (222) | putative protease |
M. marinum M | MMAR_5156 | - | 1e-116 | 84.42% (231) | hypothetical protein MMAR_5156 |
M. avium 104 | MAV_0461 | - | 1e-105 | 81.45% (221) | hypothetical protein MAV_0461 |
M. smegmatis MC2 155 | MSMEG_6180 | - | 2e-86 | 72.06% (204) | secreted protein |
M. thermoresistible (build 8) | TH_0965 | - | 6e-93 | 71.43% (217) | POSSIBLE PROTEASE |
M. ulcerans Agy99 | MUL_4242 | - | 1e-115 | 83.98% (231) | hypothetical protein MUL_4242 |
M. vanbaalenii PYR-1 | Mvan_5427 | - | 2e-92 | 69.03% (226) | peptidase S1 and S6, chymotrypsin/Hap |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_1379|M.gilvum_PYR-GCK ------------------------------------MPLGGGSGLIVNGE Mvan_5427|M.vanbaalenii_PYR-1 MRISGRSVPVRAAILALTALLTLTIVP---AHAATPVPLGGGSGLVVNGE TH_0965|M.thermoresistible__bu ----------MLPIVALTGLLVAALVPSVVAHAAGPVPLGGGSGLVVNGE MSMEG_6180|M.smegmatis_MC2_155 -------MLVGAPVVALFAVLAPWTSG--HAQAAPPVVLGGGSGIVVDGE Rv3668c|M.tuberculosis_H37Rv ----MQTAHRRFAAAFAAVLLAVVCLPANTAAADDKLPLGGGAGIVVNGD Mb3692c|M.bovis_AF2122/97 ----MQTAHRRFAAAFAAVLLAVVCLPANTAAADDKLPLGGGAGIVVNGD MMAR_5156|M.marinum_M ----MQTAHRRISSAIVTVLLALVFGPANAAAADDKVPLGGGAGIVVNGG MUL_4242|M.ulcerans_Agy99 ----MQTAHRRISSAIVTVLLALVFGPANAAAADDKVPLGGGAGIVVNGG MLBr_02295|M.leprae_Br4923 --MVLRRGHWCILVALVAVLLAVVSMPAKTVFADGRLPMGGGAGIVINGD MAV_0461|M.avium_104 -------------MAMVALLVAVTGSHPRAAAADVRIPLGGGAGIVVNGD MAB_0424|M.abscessus_ATCC_1997 ----MRYGLPVLIALFGLFAAAIPAAAAPAAGADDKVPMGGGAGLIINGD : :***:*::::* Mflv_1379|M.gilvum_PYR-GCK TLCTLTAIGTDNRGDLVGFTSAHCGGPGAVVASEAAPKAGVVGEMVAGND Mvan_5427|M.vanbaalenii_PYR-1 TLCTLTAIGTDNQGSLIGFTSAHCGGPGAVVAAEGAENTGPVGTMVAGND TH_0965|M.thermoresistible__bu TLCTLTTIGHDNRGALVGFTSAHCGGPGAVVSAEGAEDAGVLGTMVAGND MSMEG_6180|M.smegmatis_MC2_155 SFCTLTAIGHDNAGRLIGFTSAHCGGPGATVAAESDVAAGVLGTMVAGND Rv3668c|M.tuberculosis_H37Rv TMCTLTTIGHDKNGDLIGFTSAHCGGPGAQIAAEGAENAGPVGIMVAGND Mb3692c|M.bovis_AF2122/97 TMCTLTTIGHDKNGDLIGFTSAHCGGPGAQIAAEGAENAGPVGIMVAGND MMAR_5156|M.marinum_M TLCTLTTIGHDKNGDLIGFSSAHCGGPGAPVAAEGAEDKGVVGTMVAGND MUL_4242|M.ulcerans_Agy99 TLCTLTTIGHDKNGDLIGFSSAHCGGPGAPVAAEGAEDKGVVGTMVAGND MLBr_02295|M.leprae_Br4923 TMCTLTTIGTDSAAELIGFTSAHCGGPGAQVAAEGAENRGPMGTMIAGND MAV_0461|M.avium_104 TMCTLTTIGGDAAGDLIGFTSAHCGGPGAQVAAEGAENAGILGTMVAGND MAB_0424|M.abscessus_ATCC_1997 TLCTLTTIGHDGKGNLVGFTSAHCGGAGSQVASEDFPKKGVLGKFVNGNE ::****:** * . *:**:******.*: :::* * :* :: **: Mflv_1379|M.gilvum_PYR-GCK ILDYAVIKFDPAKVTPVNEVNGFRIDGLGPDPAFGEVACKLGRSTGYSCG Mvan_5427|M.vanbaalenii_PYR-1 VLDYAVIKFDPARVTPVNTVNGFRIDGLGPDPRFGDVACKLGRSTGYSCG TH_0965|M.thermoresistible__bu ALDYAVIEFDPQKVIPVNEVNGFRIDGLGPDPVFGEIACKLGRTTGHSCG MSMEG_6180|M.smegmatis_MC2_155 LLDYAVIEFDPQKVTPTNNINGFRIDGIGPDPRFGEIACKLGRTTGYSCG Rv3668c|M.tuberculosis_H37Rv GLDYAVIKFDPAKVTPVAVFNGFAINGIGPDPSFGQIACKQGRTTGNSCG Mb3692c|M.bovis_AF2122/97 GLDYAVIKFDPAKVTPVAVFNGFAINGIGPDPSFGQIACKQGRTTGNSCG MMAR_5156|M.marinum_M SLDYAVIKFDPAKVTPVANFNDFAINGIGPDPTFGQIACKQGRTTGNSCG MUL_4242|M.ulcerans_Agy99 SLDYAVIKFDPAKVTPVANFNDFAINGIGPDPTFGQIACKQGRTTGNSCG MLBr_02295|M.leprae_Br4923 NLDYAVIKFDPAKVMPVAAYNGFVISGIGQDPAFGQIACKQGRTTGNSCG MAV_0461|M.avium_104 NLDYAVIKFDPAKVTPVANFNGFLISGIGPDPAFGEIACKQGRTTGNSCG MAB_0424|M.abscessus_ATCC_1997 QYDYATIQFDPEKVQPVSTYKGFTITGIGPDPQPGDIACKLGRTTGNSCG ***.*:*** :* *. :.* * *:* ** *::*** **:** *** Mflv_1379|M.gilvum_PYR-GCK VTWGPGQEPGTILNQVCGGPGDSGGPVTVNNQLVGMLHGAFSEDLPTCVV Mvan_5427|M.vanbaalenii_PYR-1 VTWGPGQEPGTILNQVCGGPGDSGGPVTVNNRLVGMLHGAFSEDLPTCVV TH_0965|M.thermoresistible__bu VTWGPGQQPGTIVNQVCGQPGDSGAPVTVNNRLVGMIHGAFSEVLPTCVV MSMEG_6180|M.smegmatis_MC2_155 VTWGPGKDPGTIVNQVCGQPGDSGAPVTVNNLLVGMIHGAFTEDLPTCVV Rv3668c|M.tuberculosis_H37Rv VTWGPGESPGTLVMQVCGGPGDSGAPVTVDNLLVGMIHGAFSDNLPSCIT Mb3692c|M.bovis_AF2122/97 VTWGPGESPGTLVMQVCGGPGDSGAPVTVDNLLVGMIHGAFSDNLPSCIT MMAR_5156|M.marinum_M VTWGPGQDPGTILMQVCGGPGDSGAPVTVNNMLVGMIHGAFSDSLPTCIT MUL_4242|M.ulcerans_Agy99 VTWGPGQDPGTILMQVCGGPGDSGAPVTVNNMLVGMIHGAFSDSLPTCIT MLBr_02295|M.leprae_Br4923 VAWGMGETSGTLVMQVCGRPGDSGAPVTVNNLLVGMIHGAFTDNLPVCIT MAV_0461|M.avium_104 VTWGMGQSPGTIVMQVCGQPGDSGAPVTVNNQLVGMIHGAFSDNLPTCVI MAB_0424|M.abscessus_ATCC_1997 VTFGAGAEPGTFINQVCGQPGDSGAPVTVNGQLVGMIHGAATK-LPVCVI *::* * .**:: **** *****.****:. ****:*** :. ** *: Mflv_1379|M.gilvum_PYR-GCK KFIPLHTPAVTMSINTQLADITAKGR-PGSGFVPVGAR- Mvan_5427|M.vanbaalenii_PYR-1 KFIPLHTPAVTMSFNTQLADITAKGR-PGSGFVPVGATY TH_0965|M.thermoresistible__bu KFIPLHTPAVTISFNTQLADINAKNR-PGAGFVPIGAVP MSMEG_6180|M.smegmatis_MC2_155 KFVPLHTPAVTMSINTQLADITAKNR-PGTGFVPIR--- Rv3668c|M.tuberculosis_H37Rv KYIPLHTPAVVMSINADLADINAKNR-PGAGFVPVPA-- Mb3692c|M.bovis_AF2122/97 KYIPLHTPAVVMSINADLADINAKNR-PGAGFVPVPA-- MMAR_5156|M.marinum_M KYIPLHTPAVVMSMNADLDDIAAKNR-PGSGFVPVPG-- MUL_4242|M.ulcerans_Agy99 KYIPLHTPAVVMSMNADLDDIAAKNR-PGSGFVSVPG-- MLBr_02295|M.leprae_Br4923 KFIPLHTPAVVMSMNAILADVNKNNR-PGAGFVPQPV-- MAV_0461|M.avium_104 KYIPLHTPAVVMSFNAILADINAKHR-PGAGFAPLPG-- MAB_0424|M.abscessus_ATCC_1997 KYIPLHTPTTTYSINTVLADINAKNRTAGVGFTPVG--- *::*****:.. *:*: * *: : * .* **..