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M. tuberculosis H37Rv Rv3668c (-)

annotation: POSSIBLE PROTEASE
coordinates: 4109783 - 4110481
length: 232

QTAHRRFAAAFAAVLLAVVCLPANTAAADDKLPLGGGAGIVVNGDTMCTLTTIGHDKNGDLIGFTSAHCG
GPGAQIAAEGAENAGPVGIMVAGNDGLDYAVIKFDPAKVTPVAVFNGFAINGIGPDPSFGQIACKQGRTT
GNSCGVTWGPGESPGTLVMQVCGGPGDSGAPVTVDNLLVGMIHGAFSDNLPSCITKYIPLHTPAVVMSIN
ADLADINAKNRPGAGFVPVPA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3668c--100% (232)POSSIBLE PROTEASE
M. tuberculosis H37RvRv1815-2e-0530.56% (180) hypothetical protein Rv1815

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3692c-1e-136100.00% (232) putative protease
M. gilvum PYR-GCKMflv_1379-4e-8973.00% (200) peptidase S1 and S6, chymotrypsin/Hap
M. leprae Br4923MLBr_02295-1e-10677.49% (231) hypothetical protein MLBr_02295
M. abscessus ATCC 19977MAB_0424-9e-7962.61% (222) putative protease
M. marinum MMMAR_5156-1e-11684.42% (231) hypothetical protein MMAR_5156
M. avium 104MAV_0461-1e-10581.45% (221) hypothetical protein MAV_0461
M. smegmatis MC2 155MSMEG_6180-2e-8672.06% (204) secreted protein
M. thermoresistible (build 8)TH_0965-6e-9371.43% (217) POSSIBLE PROTEASE
M. ulcerans Agy99MUL_4242-1e-11583.98% (231) hypothetical protein MUL_4242
M. vanbaalenii PYR-1Mvan_5427-2e-9269.03% (226) peptidase S1 and S6, chymotrypsin/Hap

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1379|M.gilvum_PYR-GCK          ------------------------------------MPLGGGSGLIVNGE
Mvan_5427|M.vanbaalenii_PYR-1       MRISGRSVPVRAAILALTALLTLTIVP---AHAATPVPLGGGSGLVVNGE
TH_0965|M.thermoresistible__bu      ----------MLPIVALTGLLVAALVPSVVAHAAGPVPLGGGSGLVVNGE
MSMEG_6180|M.smegmatis_MC2_155      -------MLVGAPVVALFAVLAPWTSG--HAQAAPPVVLGGGSGIVVDGE
Rv3668c|M.tuberculosis_H37Rv        ----MQTAHRRFAAAFAAVLLAVVCLPANTAAADDKLPLGGGAGIVVNGD
Mb3692c|M.bovis_AF2122/97           ----MQTAHRRFAAAFAAVLLAVVCLPANTAAADDKLPLGGGAGIVVNGD
MMAR_5156|M.marinum_M               ----MQTAHRRISSAIVTVLLALVFGPANAAAADDKVPLGGGAGIVVNGG
MUL_4242|M.ulcerans_Agy99           ----MQTAHRRISSAIVTVLLALVFGPANAAAADDKVPLGGGAGIVVNGG
MLBr_02295|M.leprae_Br4923          --MVLRRGHWCILVALVAVLLAVVSMPAKTVFADGRLPMGGGAGIVINGD
MAV_0461|M.avium_104                -------------MAMVALLVAVTGSHPRAAAADVRIPLGGGAGIVVNGD
MAB_0424|M.abscessus_ATCC_1997      ----MRYGLPVLIALFGLFAAAIPAAAAPAAGADDKVPMGGGAGLIINGD
                                                                        : :***:*::::* 

Mflv_1379|M.gilvum_PYR-GCK          TLCTLTAIGTDNRGDLVGFTSAHCGGPGAVVASEAAPKAGVVGEMVAGND
Mvan_5427|M.vanbaalenii_PYR-1       TLCTLTAIGTDNQGSLIGFTSAHCGGPGAVVAAEGAENTGPVGTMVAGND
TH_0965|M.thermoresistible__bu      TLCTLTTIGHDNRGALVGFTSAHCGGPGAVVSAEGAEDAGVLGTMVAGND
MSMEG_6180|M.smegmatis_MC2_155      SFCTLTAIGHDNAGRLIGFTSAHCGGPGATVAAESDVAAGVLGTMVAGND
Rv3668c|M.tuberculosis_H37Rv        TMCTLTTIGHDKNGDLIGFTSAHCGGPGAQIAAEGAENAGPVGIMVAGND
Mb3692c|M.bovis_AF2122/97           TMCTLTTIGHDKNGDLIGFTSAHCGGPGAQIAAEGAENAGPVGIMVAGND
MMAR_5156|M.marinum_M               TLCTLTTIGHDKNGDLIGFSSAHCGGPGAPVAAEGAEDKGVVGTMVAGND
MUL_4242|M.ulcerans_Agy99           TLCTLTTIGHDKNGDLIGFSSAHCGGPGAPVAAEGAEDKGVVGTMVAGND
MLBr_02295|M.leprae_Br4923          TMCTLTTIGTDSAAELIGFTSAHCGGPGAQVAAEGAENRGPMGTMIAGND
MAV_0461|M.avium_104                TMCTLTTIGGDAAGDLIGFTSAHCGGPGAQVAAEGAENAGILGTMVAGND
MAB_0424|M.abscessus_ATCC_1997      TLCTLTTIGHDGKGNLVGFTSAHCGGAGSQVASEDFPKKGVLGKFVNGNE
                                    ::****:** *  . *:**:******.*: :::*     * :* :: **:

Mflv_1379|M.gilvum_PYR-GCK          ILDYAVIKFDPAKVTPVNEVNGFRIDGLGPDPAFGEVACKLGRSTGYSCG
Mvan_5427|M.vanbaalenii_PYR-1       VLDYAVIKFDPARVTPVNTVNGFRIDGLGPDPRFGDVACKLGRSTGYSCG
TH_0965|M.thermoresistible__bu      ALDYAVIEFDPQKVIPVNEVNGFRIDGLGPDPVFGEIACKLGRTTGHSCG
MSMEG_6180|M.smegmatis_MC2_155      LLDYAVIEFDPQKVTPTNNINGFRIDGIGPDPRFGEIACKLGRTTGYSCG
Rv3668c|M.tuberculosis_H37Rv        GLDYAVIKFDPAKVTPVAVFNGFAINGIGPDPSFGQIACKQGRTTGNSCG
Mb3692c|M.bovis_AF2122/97           GLDYAVIKFDPAKVTPVAVFNGFAINGIGPDPSFGQIACKQGRTTGNSCG
MMAR_5156|M.marinum_M               SLDYAVIKFDPAKVTPVANFNDFAINGIGPDPTFGQIACKQGRTTGNSCG
MUL_4242|M.ulcerans_Agy99           SLDYAVIKFDPAKVTPVANFNDFAINGIGPDPTFGQIACKQGRTTGNSCG
MLBr_02295|M.leprae_Br4923          NLDYAVIKFDPAKVMPVAAYNGFVISGIGQDPAFGQIACKQGRTTGNSCG
MAV_0461|M.avium_104                NLDYAVIKFDPAKVTPVANFNGFLISGIGPDPAFGEIACKQGRTTGNSCG
MAB_0424|M.abscessus_ATCC_1997      QYDYATIQFDPEKVQPVSTYKGFTITGIGPDPQPGDIACKLGRTTGNSCG
                                      ***.*:*** :* *.   :.* * *:* **  *::*** **:** ***

Mflv_1379|M.gilvum_PYR-GCK          VTWGPGQEPGTILNQVCGGPGDSGGPVTVNNQLVGMLHGAFSEDLPTCVV
Mvan_5427|M.vanbaalenii_PYR-1       VTWGPGQEPGTILNQVCGGPGDSGGPVTVNNRLVGMLHGAFSEDLPTCVV
TH_0965|M.thermoresistible__bu      VTWGPGQQPGTIVNQVCGQPGDSGAPVTVNNRLVGMIHGAFSEVLPTCVV
MSMEG_6180|M.smegmatis_MC2_155      VTWGPGKDPGTIVNQVCGQPGDSGAPVTVNNLLVGMIHGAFTEDLPTCVV
Rv3668c|M.tuberculosis_H37Rv        VTWGPGESPGTLVMQVCGGPGDSGAPVTVDNLLVGMIHGAFSDNLPSCIT
Mb3692c|M.bovis_AF2122/97           VTWGPGESPGTLVMQVCGGPGDSGAPVTVDNLLVGMIHGAFSDNLPSCIT
MMAR_5156|M.marinum_M               VTWGPGQDPGTILMQVCGGPGDSGAPVTVNNMLVGMIHGAFSDSLPTCIT
MUL_4242|M.ulcerans_Agy99           VTWGPGQDPGTILMQVCGGPGDSGAPVTVNNMLVGMIHGAFSDSLPTCIT
MLBr_02295|M.leprae_Br4923          VAWGMGETSGTLVMQVCGRPGDSGAPVTVNNLLVGMIHGAFTDNLPVCIT
MAV_0461|M.avium_104                VTWGMGQSPGTIVMQVCGQPGDSGAPVTVNNQLVGMIHGAFSDNLPTCVI
MAB_0424|M.abscessus_ATCC_1997      VTFGAGAEPGTFINQVCGQPGDSGAPVTVNGQLVGMIHGAATK-LPVCVI
                                    *::* *  .**:: **** *****.****:. ****:*** :. ** *: 

Mflv_1379|M.gilvum_PYR-GCK          KFIPLHTPAVTMSINTQLADITAKGR-PGSGFVPVGAR-
Mvan_5427|M.vanbaalenii_PYR-1       KFIPLHTPAVTMSFNTQLADITAKGR-PGSGFVPVGATY
TH_0965|M.thermoresistible__bu      KFIPLHTPAVTISFNTQLADINAKNR-PGAGFVPIGAVP
MSMEG_6180|M.smegmatis_MC2_155      KFVPLHTPAVTMSINTQLADITAKNR-PGTGFVPIR---
Rv3668c|M.tuberculosis_H37Rv        KYIPLHTPAVVMSINADLADINAKNR-PGAGFVPVPA--
Mb3692c|M.bovis_AF2122/97           KYIPLHTPAVVMSINADLADINAKNR-PGAGFVPVPA--
MMAR_5156|M.marinum_M               KYIPLHTPAVVMSMNADLDDIAAKNR-PGSGFVPVPG--
MUL_4242|M.ulcerans_Agy99           KYIPLHTPAVVMSMNADLDDIAAKNR-PGSGFVSVPG--
MLBr_02295|M.leprae_Br4923          KFIPLHTPAVVMSMNAILADVNKNNR-PGAGFVPQPV--
MAV_0461|M.avium_104                KYIPLHTPAVVMSFNAILADINAKHR-PGAGFAPLPG--
MAB_0424|M.abscessus_ATCC_1997      KYIPLHTPTTTYSINTVLADINAKNRTAGVGFTPVG---
                                    *::*****:.. *:*: * *:  : * .* **..