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RISGRSVPVRAAILALTALLTLTIVPAHAATPVPLGGGSGLVVNGETLCTLTAIGTDNQGSLIGFTSAHC GGPGAVVAAEGAENTGPVGTMVAGNDVLDYAVIKFDPARVTPVNTVNGFRIDGLGPDPRFGDVACKLGRS TGYSCGVTWGPGQEPGTILNQVCGGPGDSGGPVTVNNRLVGMLHGAFSEDLPTCVVKFIPLHTPAVTMSF NTQLADITAKGRPGSGFVPVGATY*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5427 | - | - | 100% (235) | peptidase S1 and S6, chymotrypsin/Hap |
| M. vanbaalenii PYR-1 | Mvan_3169 | - | 3e-10 | 30.19% (212) | hypothetical protein Mvan_3169 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3692c | - | 2e-92 | 69.03% (226) | putative protease |
| M. gilvum PYR-GCK | Mflv_1379 | - | 1e-108 | 91.00% (200) | peptidase S1 and S6, chymotrypsin/Hap |
| M. tuberculosis H37Rv | Rv3668c | - | 2e-92 | 69.03% (226) | protease |
| M. leprae Br4923 | MLBr_02295 | - | 4e-85 | 64.38% (219) | hypothetical protein MLBr_02295 |
| M. abscessus ATCC 19977 | MAB_0424 | - | 6e-75 | 59.65% (228) | putative protease |
| M. marinum M | MMAR_5156 | - | 5e-93 | 72.32% (224) | hypothetical protein MMAR_5156 |
| M. avium 104 | MAV_0461 | - | 3e-90 | 71.36% (220) | hypothetical protein MAV_0461 |
| M. smegmatis MC2 155 | MSMEG_6180 | - | 4e-99 | 75.78% (223) | secreted protein |
| M. thermoresistible (build 8) | TH_0965 | - | 1e-107 | 81.17% (223) | POSSIBLE PROTEASE |
| M. ulcerans Agy99 | MUL_4242 | - | 3e-92 | 71.88% (224) | hypothetical protein MUL_4242 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5427|M.vanbaalenii_PYR-1 MRISGRSVPVRAAILALTALLTLTIVP---AHAATPVPLGGGSGLVVNGE
Mflv_1379|M.gilvum_PYR-GCK ------------------------------------MPLGGGSGLIVNGE
TH_0965|M.thermoresistible__bu ----------MLPIVALTGLLVAALVPSVVAHAAGPVPLGGGSGLVVNGE
MSMEG_6180|M.smegmatis_MC2_155 -------MLVGAPVVALFAVLAPWTSG--HAQAAPPVVLGGGSGIVVDGE
MLBr_02295|M.leprae_Br4923 --MVLRRGHWCILVALVAVLLAVVSMPAKTVFADGRLPMGGGAGIVINGD
MAV_0461|M.avium_104 -------------MAMVALLVAVTGSHPRAAAADVRIPLGGGAGIVVNGD
Mb3692c|M.bovis_AF2122/97 ----MQTAHRRFAAAFAAVLLAVVCLPANTAAADDKLPLGGGAGIVVNGD
Rv3668c|M.tuberculosis_H37Rv ----MQTAHRRFAAAFAAVLLAVVCLPANTAAADDKLPLGGGAGIVVNGD
MMAR_5156|M.marinum_M ----MQTAHRRISSAIVTVLLALVFGPANAAAADDKVPLGGGAGIVVNGG
MUL_4242|M.ulcerans_Agy99 ----MQTAHRRISSAIVTVLLALVFGPANAAAADDKVPLGGGAGIVVNGG
MAB_0424|M.abscessus_ATCC_1997 ----MRYGLPVLIALFGLFAAAIPAAAAPAAGADDKVPMGGGAGLIINGD
: :***:*::::*
Mvan_5427|M.vanbaalenii_PYR-1 TLCTLTAIGTDNQGSLIGFTSAHCGGPGAVVAAEGAENTGPVGTMVAGND
Mflv_1379|M.gilvum_PYR-GCK TLCTLTAIGTDNRGDLVGFTSAHCGGPGAVVASEAAPKAGVVGEMVAGND
TH_0965|M.thermoresistible__bu TLCTLTTIGHDNRGALVGFTSAHCGGPGAVVSAEGAEDAGVLGTMVAGND
MSMEG_6180|M.smegmatis_MC2_155 SFCTLTAIGHDNAGRLIGFTSAHCGGPGATVAAESDVAAGVLGTMVAGND
MLBr_02295|M.leprae_Br4923 TMCTLTTIGTDSAAELIGFTSAHCGGPGAQVAAEGAENRGPMGTMIAGND
MAV_0461|M.avium_104 TMCTLTTIGGDAAGDLIGFTSAHCGGPGAQVAAEGAENAGILGTMVAGND
Mb3692c|M.bovis_AF2122/97 TMCTLTTIGHDKNGDLIGFTSAHCGGPGAQIAAEGAENAGPVGIMVAGND
Rv3668c|M.tuberculosis_H37Rv TMCTLTTIGHDKNGDLIGFTSAHCGGPGAQIAAEGAENAGPVGIMVAGND
MMAR_5156|M.marinum_M TLCTLTTIGHDKNGDLIGFSSAHCGGPGAPVAAEGAEDKGVVGTMVAGND
MUL_4242|M.ulcerans_Agy99 TLCTLTTIGHDKNGDLIGFSSAHCGGPGAPVAAEGAEDKGVVGTMVAGND
MAB_0424|M.abscessus_ATCC_1997 TLCTLTTIGHDGKGNLVGFTSAHCGGAGSQVASEDFPKKGVLGKFVNGNE
::****:** * . *:**:******.*: :::* * :* :: **:
Mvan_5427|M.vanbaalenii_PYR-1 VLDYAVIKFDPARVTPVNTVNGFRIDGLGPDPRFGDVACKLGRSTGYSCG
Mflv_1379|M.gilvum_PYR-GCK ILDYAVIKFDPAKVTPVNEVNGFRIDGLGPDPAFGEVACKLGRSTGYSCG
TH_0965|M.thermoresistible__bu ALDYAVIEFDPQKVIPVNEVNGFRIDGLGPDPVFGEIACKLGRTTGHSCG
MSMEG_6180|M.smegmatis_MC2_155 LLDYAVIEFDPQKVTPTNNINGFRIDGIGPDPRFGEIACKLGRTTGYSCG
MLBr_02295|M.leprae_Br4923 NLDYAVIKFDPAKVMPVAAYNGFVISGIGQDPAFGQIACKQGRTTGNSCG
MAV_0461|M.avium_104 NLDYAVIKFDPAKVTPVANFNGFLISGIGPDPAFGEIACKQGRTTGNSCG
Mb3692c|M.bovis_AF2122/97 GLDYAVIKFDPAKVTPVAVFNGFAINGIGPDPSFGQIACKQGRTTGNSCG
Rv3668c|M.tuberculosis_H37Rv GLDYAVIKFDPAKVTPVAVFNGFAINGIGPDPSFGQIACKQGRTTGNSCG
MMAR_5156|M.marinum_M SLDYAVIKFDPAKVTPVANFNDFAINGIGPDPTFGQIACKQGRTTGNSCG
MUL_4242|M.ulcerans_Agy99 SLDYAVIKFDPAKVTPVANFNDFAINGIGPDPTFGQIACKQGRTTGNSCG
MAB_0424|M.abscessus_ATCC_1997 QYDYATIQFDPEKVQPVSTYKGFTITGIGPDPQPGDIACKLGRTTGNSCG
***.*:*** :* *. :.* * *:* ** *::*** **:** ***
Mvan_5427|M.vanbaalenii_PYR-1 VTWGPGQEPGTILNQVCGGPGDSGGPVTVNNRLVGMLHGAFSEDLPTCVV
Mflv_1379|M.gilvum_PYR-GCK VTWGPGQEPGTILNQVCGGPGDSGGPVTVNNQLVGMLHGAFSEDLPTCVV
TH_0965|M.thermoresistible__bu VTWGPGQQPGTIVNQVCGQPGDSGAPVTVNNRLVGMIHGAFSEVLPTCVV
MSMEG_6180|M.smegmatis_MC2_155 VTWGPGKDPGTIVNQVCGQPGDSGAPVTVNNLLVGMIHGAFTEDLPTCVV
MLBr_02295|M.leprae_Br4923 VAWGMGETSGTLVMQVCGRPGDSGAPVTVNNLLVGMIHGAFTDNLPVCIT
MAV_0461|M.avium_104 VTWGMGQSPGTIVMQVCGQPGDSGAPVTVNNQLVGMIHGAFSDNLPTCVI
Mb3692c|M.bovis_AF2122/97 VTWGPGESPGTLVMQVCGGPGDSGAPVTVDNLLVGMIHGAFSDNLPSCIT
Rv3668c|M.tuberculosis_H37Rv VTWGPGESPGTLVMQVCGGPGDSGAPVTVDNLLVGMIHGAFSDNLPSCIT
MMAR_5156|M.marinum_M VTWGPGQDPGTILMQVCGGPGDSGAPVTVNNMLVGMIHGAFSDSLPTCIT
MUL_4242|M.ulcerans_Agy99 VTWGPGQDPGTILMQVCGGPGDSGAPVTVNNMLVGMIHGAFSDSLPTCIT
MAB_0424|M.abscessus_ATCC_1997 VTFGAGAEPGTFINQVCGQPGDSGAPVTVNGQLVGMIHGAATK-LPVCVI
*::* * .**:: **** *****.****:. ****:*** :. ** *:
Mvan_5427|M.vanbaalenii_PYR-1 KFIPLHTPAVTMSFNTQLADITAKGR-PGSGFVPVGATY
Mflv_1379|M.gilvum_PYR-GCK KFIPLHTPAVTMSINTQLADITAKGR-PGSGFVPVGAR-
TH_0965|M.thermoresistible__bu KFIPLHTPAVTISFNTQLADINAKNR-PGAGFVPIGAVP
MSMEG_6180|M.smegmatis_MC2_155 KFVPLHTPAVTMSINTQLADITAKNR-PGTGFVPIR---
MLBr_02295|M.leprae_Br4923 KFIPLHTPAVVMSMNAILADVNKNNR-PGAGFVPQPV--
MAV_0461|M.avium_104 KYIPLHTPAVVMSFNAILADINAKHR-PGAGFAPLPG--
Mb3692c|M.bovis_AF2122/97 KYIPLHTPAVVMSINADLADINAKNR-PGAGFVPVPA--
Rv3668c|M.tuberculosis_H37Rv KYIPLHTPAVVMSINADLADINAKNR-PGAGFVPVPA--
MMAR_5156|M.marinum_M KYIPLHTPAVVMSMNADLDDIAAKNR-PGSGFVPVPG--
MUL_4242|M.ulcerans_Agy99 KYIPLHTPAVVMSMNADLDDIAAKNR-PGSGFVSVPG--
MAB_0424|M.abscessus_ATCC_1997 KYIPLHTPTTTYSINTVLADINAKNRTAGVGFTPVG---
*::*****:.. *:*: * *: : * .* **..