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M. tuberculosis H37Rv Rv3650 (PE33)

annotation: PE FAMILY PROTEIN
coordinates: 4091233 - 4091517
length: 94

VSFVIAAPEALDSAATDLVVLGSTLGAATAAAAAQTTGIVAAAHDEVSAAIAALFSAHGQAYQAASAQAA
AFHTRFIRARSRHPQQETTCRRVR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3650PE33-100% (94)PE FAMILY PROTEIN
M. tuberculosis H37RvRv0746PE_PGRS96e-2876.54% (81) PE-PGRS family protein
M. tuberculosis H37RvRv0742PE_PGRS81e-2568.35% (79) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3674PE335e-47100.00% (94) PE family protein
M. gilvum PYR-GCK-----
M. leprae Br4923MLBr_01183-9e-1142.86% (77) hypothetical protein MLBr_01183
M. abscessus ATCC 19977MAB_0664-2e-0642.86% (63) PE family protein
M. marinum MMMAR_1850-3e-2469.62% (79) PE-PGRS family protein
M. avium 104MAV_2915-6e-1550.67% (75) PE family protein
M. smegmatis MC2 155MSMEG_0618-3e-0540.98% (61) PE family protein
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_0570-1e-2466.67% (81) PE_PGRS family protein
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Rv3650|M.tuberculosis_H37Rv         -MSFVIAAPEALDSAATDLVVLGSTLGAATAAAAAQTTGIVAAAHDEVSA
Mb3674|M.bovis_AF2122/97            -MSFVIAAPEALDSAATDLVVLGSTLGAATAAAAAQTTGIVAAAHDEVSA
MMAR_1850|M.marinum_M               -MSFVIAVPDFIGSAATDLTGIGSTLSAANAAAAIPTTEILAAAEDEIST
MUL_0570|M.ulcerans_Agy99           -MSFVITAPEALTAAATDLASLGSTIGAANAAAVAPTTAVLAAGADEVSA
MAV_2915|M.avium_104                -MMYVTAQPEAMNAAADRLQQIGTALAAQTGANSAPMTGVVPAAADPVSL
MLBr_01183|M.leprae_Br4923          MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLTTEIAPPAADDVSI
MAB_0664|M.abscessus_ATCC_1997      --MSLNVVPEGLTAASAAVEALTARLAAVNAAAAPVIGAVMPPAADPVSM
MSMEG_0618|M.smegmatis_MC2_155      --MTLRVVPEGLTAASSAVEALTARLAAAHAAAAPMISTVLPPAADAVSL
                                        : . *: : :*:  :  : :   *  .*       : ... * :* 

Rv3650|M.tuberculosis_H37Rv         AIAALFSAHGQAYQAASAQAAAFHTRFIRARSRHPQQETTCRRVR-----
Mb3674|M.bovis_AF2122/97            AIAALFSAHGQAYQAASAQAAAFHTRFIRARSRHPQQETTCRRVR-----
MMAR_1850|M.marinum_M               AIAALFSGHAQAYQAASAQAAAFGSRFVQALTSGAGAYTSAEAASAASIA
MUL_0570|M.ulcerans_Agy99           AVAAMFDAQGQAYQLLSARAAAFHEQFLQALSGGGASYAAGEAAAVS---
MAV_2915|M.avium_104                LAAARFAQHGQAFQAVSAEAAAVHEMFVTTLQTSAGSYAGTEAANAAAAR
MLBr_01183|M.leprae_Br4923          LLAHFFSGHGRQYQAHASQGATNHQDLIQSLLTSSSAYAGTETANHDSL-
MAB_0664|M.abscessus_ATCC_1997      QSAALFSAHGLERTGAGARAAYELGRSGVGATEAAASYTVGDIQAAATYL
MSMEG_0618|M.smegmatis_MC2_155      QTAAGFSANGAQQSAVAAQGVEELGRSGVGVGESGVSYATGDAQAAASYL
                                      *  *  :.      .:...                 :           

Rv3650|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3674|M.bovis_AF2122/97            --------------------------------------------------
MMAR_1850|M.marinum_M               DPLLAAINAPALALTGRPLIGNGANGTPGTGADGAAGGWLLGNGGAGGSG
MUL_0570|M.ulcerans_Agy99           -PLLDAINAPVLADTGRPLIGNGAN--------GGAAGWLIGNGGAGGSG
MAV_2915|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997      PGIA----------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155      TARGL---------------------------------------------
                                                                                      

Rv3650|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3674|M.bovis_AF2122/97            --------------------------------------------------
MMAR_1850|M.marinum_M               AAGSGQNGGAGGAAGLFGSGGAGGTGGSSSTGNGGAGGAGGAGGLLLGNA
MUL_0570|M.ulcerans_Agy99           TPGTASVAG-------------------------GNGGNGGAGGLLFGTG
MAV_2915|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Rv3650|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3674|M.bovis_AF2122/97            --------------------------------------------------
MMAR_1850|M.marinum_M               GTGGAGGYSNFLTASGGVGGTGGTGGLFGAGGLGGTGGASGMDTGGDGGA
MUL_0570|M.ulcerans_Agy99           GAGGAGG-----TASSLVG-------------------------------
MAV_2915|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Rv3650|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3674|M.bovis_AF2122/97            --------------------------------------------------
MMAR_1850|M.marinum_M               GGAGGLLAGLFGSGGGNGGNGGFGSVNGGAGGDGGDGGALAGPGGSGGSG
MUL_0570|M.ulcerans_Agy99           --------------------------------------------------
MAV_2915|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Rv3650|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3674|M.bovis_AF2122/97            --------------------------------------------------
MMAR_1850|M.marinum_M               AFGGTLGGDGGAGGAAGLLFGPGGSGGAGGATFSGTGGVGGAGGHAGLFG
MUL_0570|M.ulcerans_Agy99           ---AIPGGNGGYGGDGGLLFGRGGAGGAGGFGNNTTGGIGGLGGAGGLFG
MAV_2915|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Rv3650|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3674|M.bovis_AF2122/97            --------------------------------------------------
MMAR_1850|M.marinum_M               DGGAGAVGGFSSVDGGAGGAGGDAGWFGNGGIGGAGGAGYFSSGGVGGGG
MUL_0570|M.ulcerans_Agy99           AGGDGGVGGFG---------------------------------------
MAV_2915|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Rv3650|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3674|M.bovis_AF2122/97            --------------------------------------------------
MMAR_1850|M.marinum_M               GTGGVLFGNGGAGGNGGTASTGGAGGGGGAGVLIGNGGNAGIGGAGVTVG
MUL_0570|M.ulcerans_Agy99           -------------------------------TFAGNGGDGGTG-------
MAV_2915|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Rv3650|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3674|M.bovis_AF2122/97            --------------------------------------------------
MMAR_1850|M.marinum_M               GTGVGGTSGLLLGLDGFNAPASASPIHALQQQALTAINGPIQTLTGRPLI
MUL_0570|M.ulcerans_Agy99           --------------------------------------------------
MAV_2915|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Rv3650|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3674|M.bovis_AF2122/97            --------------------------------------------------
MMAR_1850|M.marinum_M               GNGTPAAAGSGADGAAGGWLLGDGGAGGSAPLFTAQDAGAGGAAGLWGTG
MUL_0570|M.ulcerans_Agy99           ---------------------------------------------LFAAG
MAV_2915|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Rv3650|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3674|M.bovis_AF2122/97            --------------------------------------------------
MMAR_1850|M.marinum_M               GTGGAGGTSTGGLGGAGGEGGAGGFLAGTGGAGGAGGFSPATGTGAGGVG
MUL_0570|M.ulcerans_Agy99           GDSGAGGDSVG---------------------------------------
MAV_2915|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Rv3650|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3674|M.bovis_AF2122/97            --------------------------------------------------
MMAR_1850|M.marinum_M               GAGGAGGLFGGGGGGGVGGGSLAGPGGGGGAGGAGGPLSGLVGAGGGAGG
MUL_0570|M.ulcerans_Agy99           --------------------------------------------------
MAV_2915|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Rv3650|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3674|M.bovis_AF2122/97            --------------------------------------------------
MMAR_1850|M.marinum_M               HGGPGDTDGGDGGAGGNGGLLGGAGGAGGTGGYSDDAPSSNGGAGGNAGL
MUL_0570|M.ulcerans_Agy99           --------------------------------------------------
MAV_2915|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Rv3650|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3674|M.bovis_AF2122/97            --------------------------------------------------
MMAR_1850|M.marinum_M               LFGNGGHGGSGGASRGFAGTGGAGGNAGLLFGSGGFGGFGGFGSGGGSGG
MUL_0570|M.ulcerans_Agy99           ------------------------------------------GADGGDGG
MAV_2915|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Rv3650|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3674|M.bovis_AF2122/97            --------------------------------------------------
MMAR_1850|M.marinum_M               NGGNAGLFGSGGDGGAGGFGVFIDGGSGGSGGSGGPLLGTGGSGGAGGEC
MUL_0570|M.ulcerans_Agy99           NGGKAGLVGQGGDGGAGGN-------------------------------
MAV_2915|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Rv3650|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3674|M.bovis_AF2122/97            --------------------------------------------------
MMAR_1850|M.marinum_M               DLGGFGDGGDGGDGGGAMLIGNGGNGGNGAAGATAGTDGKGGAGGTGGTL
MUL_0570|M.ulcerans_Agy99           NNSGFGTGGSGGKGGDAVLIGNGGNGGNAGSGGVG--PGIAGAAGIGGLL
MAV_2915|M.avium_104                --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0618|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Rv3650|M.tuberculosis_H37Rv         -----------
Mb3674|M.bovis_AF2122/97            -----------
MMAR_1850|M.marinum_M               LGEDGLNGLT-
MUL_0570|M.ulcerans_Agy99           IGEDGMAGLTP
MAV_2915|M.avium_104                -----------
MLBr_01183|M.leprae_Br4923          -----------
MAB_0664|M.abscessus_ATCC_1997      -----------
MSMEG_0618|M.smegmatis_MC2_155      -----------