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VAIANPAEPGAAGRHHQPRGDRKPRAWRQCGPQNGPRRSQAITPEPGAAGRHHQPRGDRKPRAWRQCGPQ NGPRRSQAITPEPGAAGRHHQPRGDRKPRAWRQCGPQNGPRRSQAITPEPGAAGRHHQPRGDRKPRAWRQ CGPQNGPRRSQAITPEPGAAGRHHQPRGDRKPRAWRQCGPQNGPRRSQAITPEPGAAGRHWLDQRPVVPD GVGKSDS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3611 | - | - | 100% (217) | HYPOTHETICAL ARGININE AND PROLINE RICH PROTEIN |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3641 | - | 1e-109 | 100.00% (173) | hypothetical protein Mb3641 |
| M. gilvum PYR-GCK | Mflv_4039 | infB | 1e-07 | 30.41% (194) | translation initiation factor IF-2 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_0680 | - | 1e-06 | 26.83% (164) | hypothetical protein MAV_0680 |
| M. smegmatis MC2 155 | MSMEG_6421 | - | 4e-07 | 30.56% (180) | transcriptional regulator |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0574 | - | 9e-06 | 23.63% (182) | iron-sulphur-binding reductase |
| M. vanbaalenii PYR-1 | Mvan_2314 | infB | 5e-06 | 29.81% (161) | translation initiation factor IF-2 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3611|M.tuberculosis_H37Rv --------------------------------------------------
Mb3641|M.bovis_AF2122/97 --------------------------------------------------
Mflv_4039|M.gilvum_PYR-GCK -------------MAGKARVHELAKELGVTSKEVLARLGEQGEFVKSASS
Mvan_2314|M.vanbaalenii_PYR-1 -------------MAGKARVHELAKELGVTSKEVLARLSEQGEFVKSASS
MAV_0680|M.avium_104 --------------------------------------------MVGAAA
MSMEG_6421|M.smegmatis_MC2_155 MAQRNRPQGHRPGPPAGARRRPRRPRPRRADRVTRARVLRRGPHPGPECR
MUL_0574|M.ulcerans_Agy99 -----MTTQMLIRLTVGMGMTAVVVVLALRRVWWLYKLIMSGQPASGRTD
Rv3611|M.tuberculosis_H37Rv --------------------------------MA------IANPAEPG--
Mb3641|M.bovis_AF2122/97 --------------------------------MA------IANPAEPG--
Mflv_4039|M.gilvum_PYR-GCK TVEAPVARRLRESFGGNKPDAVKPAAG--ASNGA------PAKPSAPGAR
Mvan_2314|M.vanbaalenii_PYR-1 TVEAPVARRLRESYGGSKSDKTKAAPSGNGAAGA------TVKPSAPQSR
MAV_0680|M.avium_104 VAAGLGISAASLNAGSAYSAPLDPPPPCPNCHGG------GGNPGGPGGG
MSMEG_6421|M.smegmatis_MC2_155 RRTRRVVRHVVAHPGAARLGLCQRVGRGDHRRGF------PAHPPAPTRH
MUL_0574|M.ulcerans_Agy99 DIGARIWTQIAEVFGQRRLLRWSIPGIAHFFTMWGFFILLTVYIEAYGFL
Rv3611|M.tuberculosis_H37Rv -----AAGRHHQPRGDRKPRAWRQCGPQNGPRRSQAITPEPGAAGRHHQP
Mb3641|M.bovis_AF2122/97 -----AAG-------------------------------------RHHQP
Mflv_4039|M.gilvum_PYR-GCK PGPRPGPPAPAQPKEPPAPAAPAAAAPAPAAPAPPAAPPAPAASAAPPSA
Mvan_2314|M.vanbaalenii_PYR-1 PGPKPGPPVAQQPAAPAAPPAAPPAPPTPAAAPPSPAPAAPAA--ATPAE
MAV_0680|M.avium_104 PGGQPAGPGGGAGGQHGGNTPPQGGQNNPPQNGPNNAPQNGPN--NAPQS
MSMEG_6421|M.smegmatis_MC2_155 QPHAGVGALGAAARGLPPLPGLQRGPGQSGDGPGVRLRVAAHRAAVAADH
MUL_0574|M.ulcerans_Agy99 FVENFSIPVIGHWDALGFLQDFFATAVFLGIATFAIIRIKRNPREIGRAS
Rv3611|M.tuberculosis_H37Rv RGDRKPRAWRQCGPQNGP---------RRS-QAITPEPGAAG--------
Mb3641|M.bovis_AF2122/97 RGDRKPRAWRQCGPQNGP---------RRS-QAITPEPGAAG--------
Mflv_4039|M.gilvum_PYR-GCK PEAPSAR--PTPGPRPGP---------GGP-KPGAPKPAPRTPRVGNNPF
Mvan_2314|M.vanbaalenii_PYR-1 PAAPSARPGPTPGPRPGP---------SAP-KPGAPKPAARTPRVGNNPF
MAV_0680|M.avium_104 GPNNPSQGGPNNAPQNGP---------NNPPQGGQNEPGGQYPP---NQH
MSMEG_6421|M.smegmatis_MC2_155 RPHSDRRGRVRRVCPVGA---------TSRLVAVAATYIAEMNGFTPADG
MUL_0574|M.ulcerans_Agy99 RFYGSHNSGAWLVLFMIFNVIWTYVLVRGSAVNNETLPYGKGAFLSQLFA
.
Rv3611|M.tuberculosis_H37Rv RHHQPRGDRKPRAWR---QCGPQNGPRRSQAIT---PEPGAAGRHHQPRG
Mb3641|M.bovis_AF2122/97 RHHQPRGDRKPRAWR---QCGPQNGPRRSQAIT---PEPGAAGRHHQPRG
Mflv_4039|M.gilvum_PYR-GCK SSQQPVERPAPRPQGPAGPGGPRPGPGAGGPRPGGGPRPGATPGNMPPRP
Mvan_2314|M.vanbaalenii_PYR-1 SSQQPVERPAPRPQ---GPGGPRPGPGAGGPRPGGGPRPGASPGSMPPRP
MAV_0680|M.avium_104 GQNPPQNGQNQPPYDHDQNPPTPGGPTNAPANTQNPPPPPERQRYAALNP
MSMEG_6421|M.smegmatis_MC2_155 DRDPRMRRPGTPRPSGEPSQFIRRDPNYRPPQPPPRPAPPPPARRVPPPP
MUL_0574|M.ulcerans_Agy99 AILRPLGQPANEIIETTALLAHIAVMLAFLIIVLHSKHLHIFLAPINVTF
Rv3611|M.tuberculosis_H37Rv DRKPRAWRQCGPQNGPRRSQAITPEPGAAGR-------------------
Mb3641|M.bovis_AF2122/97 DRKPRAWRQCGPQNGPRRSQAITPEPGAAGR-------------------
Mflv_4039|M.gilvum_PYR-GCK VGGPRPGGGPRPGGGPRPGAGPRPTPGGAGRPGGGGGG--NYRGGGAGGG
Mvan_2314|M.vanbaalenii_PYR-1 QG-ARPGGGPRPGGGPRPGGGPRPTPGGAGRPGGGGGGGGNYRGGGAGG-
MAV_0680|M.avium_104 PNTQPPHPPYVPRHDVVTASAQIGGPAGADVQFSIVG-------------
MSMEG_6421|M.smegmatis_MC2_155 PRQAPPPPPRRPAAPPPAPPPPGRSPGQSPGQSSRPP-------------
MUL_0574|M.ulcerans_Agy99 KRLPDGLGPLLPVEADGKPVDFENPPDDAIFGRGKIEDFTWKG----MLD
* * :
Rv3611|M.tuberculosis_H37Rv -----------HHQPR--------GDRKPRAWRQCGPQNGPRRS------
Mb3641|M.bovis_AF2122/97 -----------HHQPR--------GDRKPRAWRQCGPQNGPRRS------
Mflv_4039|M.gilvum_PYR-GCK GGAGGAAAGGFRGRPGGGGG--RPGQRGGAAGAFGRPGGAPKRGRKSKRA
Mvan_2314|M.vanbaalenii_PYR-1 -GAPAAGGGGFRGRPGGGGGGGRPGQRGGAAGAFGRPGGAPKRGRKSKRA
MAV_0680|M.avium_104 -----------RGAPP-------PPREHGYGWNDGPPPHHPPPN------
MSMEG_6421|M.smegmatis_MC2_155 -----------RQFPP-------PPTRRKTSTPTAAAQSAPPAP------
MUL_0574|M.ulcerans_Agy99 FATCTECGRCQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGEKTAD
* *
Rv3611|M.tuberculosis_H37Rv --------------------------------------------------
Mb3641|M.bovis_AF2122/97 --------------------------------------------------
Mflv_4039|M.gilvum_PYR-GCK KRAEYENMQAPVVGGVRLPHGNGETIRLARGASLSDFADKINANPASLVQ
Mvan_2314|M.vanbaalenii_PYR-1 KRAEYENMQAPVVGGVRLPHGNGETIRLARGASLSDFAEKINANPASLVQ
MAV_0680|M.avium_104 --------------------------------------------------
MSMEG_6421|M.smegmatis_MC2_155 --------------------------------------------------
MUL_0574|M.ulcerans_Agy99 LLEGLDLETAAGEGHHVPESGFGRVPGDGPEQAARPLVGTAEQGGVIDPD
Rv3611|M.tuberculosis_H37Rv -------------------------------QAITPE-------------
Mb3641|M.bovis_AF2122/97 -------------------------------QAITPE-------------
Mflv_4039|M.gilvum_PYR-GCK ALFNLGEMVTATQSVNDETLELLGGEMNYVVQVVSPEDEDRELLQSFDLS
Mvan_2314|M.vanbaalenii_PYR-1 ALFNLGEMVTATQSVGDETLELLGGEMNYVVQVVSPEDEDRELLESFDLT
MAV_0680|M.avium_104 -----------------------------WYGPPPPGGWDGP--------
MSMEG_6421|M.smegmatis_MC2_155 ----------------------------TVRKPRRRRRWGRIVLALLMIA
MUL_0574|M.ulcerans_Agy99 VLWSCVSCGACVEQCPVDIEHIDHIVDMRRYQVMMESEFPSELSVLFKNL
Rv3611|M.tuberculosis_H37Rv --PGAAGRHWLDQRPVVPDGVGKSDS------------------------
Mb3641|M.bovis_AF2122/97 --PGAAGRHWLDQRPVVPDGVGKSDS------------------------
Mflv_4039|M.gilvum_PYR-GCK YGEDEGGEDDLEFRPPVVTVMGHVDHGKTRLLDTIRDATVREGEAGGITQ
Mvan_2314|M.vanbaalenii_PYR-1 YGEDEGGEEDLEIRPPVVTVMGHVDHGKTRLLDTIRNATVREGEAGGITQ
MAV_0680|M.avium_104 --PPPGGWNRPWDGPPRDVAVARADFG-PFSYNTFTVIPVFNWQYGGWGY
MSMEG_6421|M.smegmatis_MC2_155 VLAGAGAMIWVDTSLQRIPALAGYPERPAAGRGTTWLLVGSDSREGLTPE
MUL_0574|M.ulcerans_Agy99 ENKGNPWGQNASDRTNWIDEVDFDVPVYGEDVDSFDGYEYLFWVGCAGAY
:
Rv3611|M.tuberculosis_H37Rv --------------------------------------------------
Mb3641|M.bovis_AF2122/97 --------------------------------------------------
Mflv_4039|M.gilvum_PYR-GCK HIGAYQVTVDLDGNERPITFIDTPGHEAFTAMRARGAKATDIAILVVAAD
Mvan_2314|M.vanbaalenii_PYR-1 HIGAYQVTVDLDGTERPITFIDTPGHEAFTAMRARGAKATDIAILVVAAD
MAV_0680|M.avium_104 WFFGVWVPLY----------------------------------------
MSMEG_6421|M.smegmatis_MC2_155 QQASLTTGGDLG----------------------------------TGRT
MUL_0574|M.ulcerans_Agy99 DDKAKKTTKAVAELLATAGVKFMVLGAGETCNGDSARRSGNEFLFQQLAQ
Rv3611|M.tuberculosis_H37Rv --------------------------------------------------
Mb3641|M.bovis_AF2122/97 --------------------------------------------------
Mflv_4039|M.gilvum_PYR-GCK DGVMPQTVEAVNHAQAADVPIVVAVNKIDKEGADPAKIRGQLTEYGLVPE
Mvan_2314|M.vanbaalenii_PYR-1 DGVMPQTVEAINHAQAADVPIVVAVNKIDKEGADPAKIRGQLTEYGLVPE
MAV_0680|M.avium_104 --------------------------------------------------
MSMEG_6421|M.smegmatis_MC2_155 DTILLVHIPALGSSTPATMVSIPRDSYVEIPGYGEDKINAAFALG-----
MUL_0574|M.ulcerans_Agy99 QAIETLDGVFEGVETVDRKVVVTCPHCFNTLGKEYRQLGSNYSVLHHTQL
Rv3611|M.tuberculosis_H37Rv --------------------------------------------------
Mb3641|M.bovis_AF2122/97 --------------------------------------------------
Mflv_4039|M.gilvum_PYR-GCK EYGGDTMFVDISAKAGTNIEALLEAVVLTADASLDLRANPDMEAQGVAIE
Mvan_2314|M.vanbaalenii_PYR-1 EYGGDAMFVDISAKQGTNIEALLEAVILTADASLDLRANPDMEAQGVAIE
MAV_0680|M.avium_104 --------------------------------------------------
MSMEG_6421|M.smegmatis_MC2_155 --------------------------------GAPLLAQTVESATGLRLD
MUL_0574|M.ulcerans_Agy99 LNRLIRDKKLVPVTPVSQDVTYHDPCYLGRHNKVYEAPRELIGAAGANLA
Rv3611|M.tuberculosis_H37Rv --------------------------------------------------
Mb3641|M.bovis_AF2122/97 --------------------------------------------------
Mflv_4039|M.gilvum_PYR-GCK AHLDRGRGPVAT-------------------VLIQRGTLRVGDSVVAGDA
Mvan_2314|M.vanbaalenii_PYR-1 AHLDRGRGPVAT-------------------VLIQRGTLRVGDSVVAGDA
MAV_0680|M.avium_104 --------------------------------------------------
MSMEG_6421|M.smegmatis_MC2_155 HYAEIGFGGFAS-------------------LVDAVGGVTVCPAEPISDP
MUL_0574|M.ulcerans_Agy99 EMPRHAERSFCCGAGGARMWMEEHIGKRINHERVDEAVATNASTIATACP
Rv3611|M.tuberculosis_H37Rv --------------------------------------------------
Mb3641|M.bovis_AF2122/97 --------------------------------------------------
Mflv_4039|M.gilvum_PYR-GCK YGRVRRMVDEHGEDVEEALPSRPVQVIGFTSVPGAGDNFLVVDEDRIARQ
Mvan_2314|M.vanbaalenii_PYR-1 YGRVRRMVDEHGEDVEEALPSRPVQVIGFTSVPGAGDNFLVVDEDRIARQ
MAV_0680|M.avium_104 --------------------------------------------------
MSMEG_6421|M.smegmatis_MC2_155 LAGIDLPAGCQELDGRTALGFVRTRATARADLDRMIHQREFMSGLLHRAA
MUL_0574|M.ulcerans_Agy99 FCRVMVTDGVNDRQEEAGRSGVEVLDVAQVLLGSLDREKATLPEKGTAAK
Rv3611|M.tuberculosis_H37Rv --------------------------------------------------
Mb3641|M.bovis_AF2122/97 --------------------------------------------------
Mflv_4039|M.gilvum_PYR-GCK IADRRSARKRNALAARTRKRISLEDLDSALKETSQLNLILKGDNSGTVEA
Mvan_2314|M.vanbaalenii_PYR-1 IADRRSARKRNALAARTRKRISLEDLDSALKETSQLNLILKGDNSGTVEA
MAV_0680|M.avium_104 --------------------------------------------------
MSMEG_6421|M.smegmatis_MC2_155 SPAVWLNPLRWSPMMRAATGTLAVDEDAHVWNLARLAWSLRGDPVTMTVP
MUL_0574|M.ulcerans_Agy99 EAEKRAKTAPKAAAPAAPAPAPAEAPAKAAEASAAATAASPAAPAKGLGM
Rv3611|M.tuberculosis_H37Rv --------------------------------------------------
Mb3641|M.bovis_AF2122/97 --------------------------------------------------
Mflv_4039|M.gilvum_PYR-GCK LEEALLGIQVDDEVQLRVIDRGVGGVTETNVNLASASDAIIIGFNVRAEG
Mvan_2314|M.vanbaalenii_PYR-1 LEEALLGIQVDDEVELRVIDRGVGGVTETNVNLASASDAIIIGFNVRAEG
MAV_0680|M.avium_104 --------------------------------------------------
MSMEG_6421|M.smegmatis_MC2_155 IG-----------------EFGSNGSGDVVMWDSDAAPRLFEALRTDAPV
MUL_0574|M.ulcerans_Agy99 AGGAKRPGAKKAAPAPAAETAAAEAPAAPAKGLGMAAGAKKPGAKKAAAP
Rv3611|M.tuberculosis_H37Rv --------------------------------------------------
Mb3641|M.bovis_AF2122/97 --------------------------------------------------
Mflv_4039|M.gilvum_PYR-GCK KATELANREGVEIRYYSIIYQAIDEIESALKGMLKPIYEEKELGRAEIRA
Mvan_2314|M.vanbaalenii_PYR-1 KATELANREGVEIRYYSIIYQAIDEIESALKGMLKPVYEEKELGRAEIRA
MAV_0680|M.avium_104 --------------------------------------------------
MSMEG_6421|M.smegmatis_MC2_155 PPDVLENAVN----------------------------------------
MUL_0574|M.ulcerans_Agy99 TGETKPAEAAAPAAPVKGLGMASGAKRPGAKKAAPPAAAAPEAAATAPAP
Rv3611|M.tuberculosis_H37Rv --------------------------------------------------
Mb3641|M.bovis_AF2122/97 --------------------------------------------------
Mflv_4039|M.gilvum_PYR-GCK IFRSSKVGNIAGCLVQSGIMRRN-AKARLLRDNVVVAQNLTVSSLKREKD
Mvan_2314|M.vanbaalenii_PYR-1 IFRSSKVGNIAGCLVQSGIMRRN-AKARLLRDNVVVAENLTISSLKREKD
MAV_0680|M.avium_104 --------------------------------------------------
MSMEG_6421|M.smegmatis_MC2_155 --------------------------------------------------
MUL_0574|M.ulcerans_Agy99 EAAAAPAEPAAPAAPVKGLGIATGAKRPGAKKAPARAEAPSAAAPAQPEP
Rv3611|M.tuberculosis_H37Rv -----------------------------------------
Mb3641|M.bovis_AF2122/97 -----------------------------------------
Mflv_4039|M.gilvum_PYR-GCK DATEVREGYECGLTLTYNDIKEGDVIETYELVEKART----
Mvan_2314|M.vanbaalenii_PYR-1 DVTEVRDGYECGLTLTYSDIKEGDVIETYELVEKART----
MAV_0680|M.avium_104 -----------------------------------------
MSMEG_6421|M.smegmatis_MC2_155 -----------------------------------------
MUL_0574|M.ulcerans_Agy99 EATPEPEPASKQDGEPTPPAAPAAPVKGLGMARGARPPGKR