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TTQMLIRLTVGMGMTAVVVVLALRRVWWLYKLIMSGQPASGRTDDIGARIWTQIAEVFGQRRLLRWSIPG IAHFFTMWGFFILLTVYIEAYGFLFVENFSIPVIGHWDALGFLQDFFATAVFLGIATFAIIRIKRNPREI GRASRFYGSHNSGAWLVLFMIFNVIWTYVLVRGSAVNNETLPYGKGAFLSQLFAAILRPLGQPANEIIET TALLAHIAVMLAFLIIVLHSKHLHIFLAPINVTFKRLPDGLGPLLPVEADGKPVDFENPPDDAIFGRGKI EDFTWKGMLDFATCTECGRCQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGEKTADLLEGLDLETA AGEGHHVPESGFGRVPGDGPEQAARPLVGTAEQGGVIDPDVLWSCVSCGACVEQCPVDIEHIDHIVDMRR YQVMMESEFPSELSVLFKNLENKGNPWGQNASDRTNWIDEVDFDVPVYGEDVDSFDGYEYLFWVGCAGAY DDKAKKTTKAVAELLATAGVKFMVLGAGETCNGDSARRSGNEFLFQQLAQQAIETLDGVFEGVETVDRKV VVTCPHCFNTLGKEYRQLGSNYSVLHHTQLLNRLIRDKKLVPVTPVSQDVTYHDPCYLGRHNKVYEAPRE LIGAAGANLAEMPRHAERSFCCGAGGARMWMEEHIGKRINHERVDEAVATNASTIATACPFCRVMVTDGV NDRQEEAGRSGVEVLDVAQVLLGSLDREKATLPEKGTAAKEAEKRAKTAPKAAAPAAPAPAPAEAPAKAA EASAAATAASPAAPAKGLGMAGGAKRPGAKKAAPAPAAETAAAEAPAAPAKGLGMAAGAKKPGAKKAAAP TGETKPAEAAAPAAPVKGLGMASGAKRPGAKKAAPPAAAAPEAAATAPAPEAAAAPAEPAAPAAPVKGLG IATGAKRPGAKKAPARAEAPSAAAPAQPEPEATPEPEPASKQDGEPTPPAAPAAPVKGLGMARGARPPGK R*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0574 | - | - | 100% (982) | iron-sulphur-binding reductase |
| M. ulcerans Agy99 | MUL_1004 | - | 3e-19 | 35.40% (274) | hypothetical protein MUL_1004 |
| M. ulcerans Agy99 | MUL_2122 | infB | 7e-16 | 32.42% (256) | translation initiation factor IF-2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0345c | - | 0.0 | 81.46% (933) | putative iron-sulfur-binding reductase |
| M. gilvum PYR-GCK | Mflv_0278 | - | 0.0 | 66.42% (1060) | hypothetical protein Mflv_0278 |
| M. tuberculosis H37Rv | Rv0338c | - | 0.0 | 81.24% (933) | iron-sulfur-binding reductase |
| M. leprae Br4923 | MLBr_02501 | - | 0.0 | 74.13% (924) | putative iron-sulphur-binding reductase |
| M. abscessus ATCC 19977 | MAB_4293 | - | 0.0 | 54.95% (990) | putative Fe-S oxidoreductase |
| M. marinum M | MMAR_0611 | - | 0.0 | 98.88% (985) | iron-sulphur-binding reductase |
| M. avium 104 | MAV_4817 | - | 0.0 | 79.71% (976) | ferredoxin, 4Fe-4S |
| M. smegmatis MC2 155 | MSMEG_0690 | - | 0.0 | 68.33% (1042) | iron-sulfur cluster-binding protein |
| M. thermoresistible (build 8) | TH_2670 | - | 2e-34 | 46.19% (197) | PUTATIVE - |
| M. vanbaalenii PYR-1 | Mvan_0619 | - | 0.0 | 69.22% (1030) | hypothetical protein Mvan_0619 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0278|M.gilvum_PYR-GCK -METQMLIRIIAGVLMLAVVGVFAAKRVLWLTKLIRSGQPLSEGNNRKDH
Mvan_0619|M.vanbaalenii_PYR-1 -MDTQMLIRIVVGVLMIAVVGVFAVKRVLWLTTLIRSGQPMSEGNNRKDH
MUL_0574|M.ulcerans_Agy99 -MTTQMLIRLTVGMGMTAVVVVLALRRVWWLYKLIMSGQ---PASGRTDD
MMAR_0611|M.marinum_M -MTTQMLIRLTVGMGMTAVVVVLALRRVWWLYKLIMSGQ---PASGRTDD
Mb0345c|M.bovis_AF2122/97 -MTTQTLIRLILGMSMTAVVGVFALRRVWWLYKLVMSGQ---PASGRTDN
Rv0338c|M.tuberculosis_H37Rv -MTTQTLIRLILGMSMTAVVGVFALRRVWWLYKLVMSGQ---PASGRTDN
MAV_4817|M.avium_104 -MTTQMLIRLVVGMGMTLIVAALAARRVLWLFKLITSGK---PAPGHTDD
MLBr_02501|M.leprae_Br4923 -MTTQMLIRMVLGLSMTAVVLLFAARRVLWLYKLTMSGQ---PANGRTDE
MSMEG_0690|M.smegmatis_MC2_155 MAHTLEVSRLIIGLLMTAIVLVFAAKRVLWLTKLIRSGQKTLDENGRKND
MAB_4293|M.abscessus_ATCC_1997 -MSTATITLGIIGVIFSLVAWGSFFGGVVKMVRVILSGQ---PDRTRFRP
TH_2670|M.thermoresistible__bu --------------------------------------------------
Mflv_0278|M.gilvum_PYR-GCK LQKRITTQFEEVFGQTRLLRWSIPGIAHFFTMWGFFVLATVYLEAFGLLV
Mvan_0619|M.vanbaalenii_PYR-1 LKQRITTQFEEVFGQTRLLRWSVPGIAHFFTMWGFFVLATVYIEAFGQLV
MUL_0574|M.ulcerans_Agy99 IGARIWTQIAEVFGQRRLLRWSIPGIAHFFTMWGFFILLTVYIEAYGFLF
MMAR_0611|M.marinum_M IGARIWTQIAEVFGQRRLLRWSIPGIAHFFTMWGFFILLTVYIEAYGFLF
Mb0345c|M.bovis_AF2122/97 LGTRIWTQISEVLGQRRLLKWSIPGLAHFFTMWGFFILLTVYIEAYGLLF
Rv0338c|M.tuberculosis_H37Rv LGTRIWTQISEVLGQRRLLKWSIPGLAHFFTMWGFFILLTVYIEAYGLLF
MAV_4817|M.avium_104 PGKRVWAEVSEVFGQRRLLKWSIPGLAHFFTMWGFFILLTVYIEAYGLLF
MLBr_02501|M.leprae_Br4923 LGTRIWTQITEVFGQRRLLQWSLPGLTHLFTMWGFFILLTVYIEAYGVLF
MSMEG_0690|M.smegmatis_MC2_155 LQKRITTQITEVFGQTRLLRWSVPGIAHFFTMWGFFVLASVYLEAYGVLF
MAB_4293|M.abscessus_ATCC_1997 FLPRLKQLIVEVVAHTRMNKFRTVGWAHWLVMVGFLGGFPLYFESYGQTF
TH_2670|M.thermoresistible__bu --------------------------------------------------
Mflv_0278|M.gilvum_PYR-GCK DHDFHIPLIGRWDALGFLQDFFAVAVLLGIITFAIIRIVREPKKHGRDSR
Mvan_0619|M.vanbaalenii_PYR-1 DHDFHIPLVGRWDALGFLQDFFAVAVLLGIITFAIIRIVREPKKHGRDSR
MUL_0574|M.ulcerans_Agy99 VENFSIPVIGHWDALGFLQDFFATAVFLGIATFAIIRIKRNPREIGRASR
MMAR_0611|M.marinum_M VENFSIPVIGHWDALGFLQDFFATAVFLGIATFAIIRIKRNPREIGRASR
Mb0345c|M.bovis_AF2122/97 EERFHIPVIGRWDALGFLQDFFATAVFLGITTFAIIRILRNPREIGRSSR
Rv0338c|M.tuberculosis_H37Rv EERFHIPVIGRWDALGFLQDFFATAVFLGITTFAIIRILRNPREIGRSSR
MAV_4817|M.avium_104 QDNFHIPIIGRWDALGFLQDFFATAVFLGIATFAVIRSMRSPREIGRSSR
MLBr_02501|M.leprae_Br4923 QPNFHLPIIGRWNAIGFLQDFFALAVLTSTVTFAIIRMRNEPKEYGRKSR
MSMEG_0690|M.smegmatis_MC2_155 DPEFHIPFIGRWPVLGFLQDFFAVAVLLGIIVFAIIRVVREPKKIGRDSR
MAB_4293|M.abscessus_ATCC_1997 NPEFHWPIIGDTFLWHLWDELLGIGTVIGIVTLIIIRQLNHPRKPERLSR
TH_2670|M.thermoresistible__bu --------------------------------------------------
Mflv_0278|M.gilvum_PYR-GCK FYGSHTGGAWLILFMIFNVIWTYALVRGAAAV--VGNLPYGNGAFFSQFM
Mvan_0619|M.vanbaalenii_PYR-1 FYGSHTGGAWLILFMIFNVIWTYALVRGAGAN--TGALPYGNGAFFSQFM
MUL_0574|M.ulcerans_Agy99 FYGSHNSGAWLVLFMIFNVIWTYVLVRGSAVN--NETLPYGKGAFLSQLF
MMAR_0611|M.marinum_M FYGSHNSGAWLVLFMIFNVIWTYVLVRGSAVN--NETLPYGKGAFLSQLF
Mb0345c|M.bovis_AF2122/97 FYGSHNGGAWLVLLMIFNVIWTYVLVRGSAVN--NGTLPYGNGAFLSQLF
Rv0338c|M.tuberculosis_H37Rv FYGSHNGGAWLVLLMIFNVIWTYVLVRGSAVN--NGTLPYGNGAFLSQLF
MAV_4817|M.avium_104 FYGSHTGGAWLVLFMIFNVIWTYVLVRGSAVN--NGTLPYGKGAFLSQLF
MLBr_02501|M.leprae_Br4923 FYGSHTGGAWLILFMIFNVIWTYAVFRGASVDALGEAFPYNSGAFFSHAI
MSMEG_0690|M.smegmatis_MC2_155 FYGSHTGGAWEILFMIFLVIATYALFRGAAVNTLGERFPYQSGAFFSDFM
MAB_4293|M.abscessus_ATCC_1997 FGGSNFFAAYTIEMIVLVEGLGMVLVKSGKIATFHNSHPSSD--FFTMNV
TH_2670|M.thermoresistible__bu --------------------------------------------------
Mflv_0278|M.gilvum_PYR-GCK GWIMRPLGHTANEWIETIALLAHIAIMLVFLLIVLHSKHLHIGLAPINVT
Mvan_0619|M.vanbaalenii_PYR-1 GWIMHPLGEPANEWIETLALLAHIAIMLVFLLIVLHSKHLHIGLAPINVT
MUL_0574|M.ulcerans_Agy99 AAILRPLGQPANEIIETTALLAHIAVMLAFLIIVLHSKHLHIFLAPINVT
MMAR_0611|M.marinum_M GAILRPLGQPANEIIETTALLAHIAVMLAFLIIVLHSKHLHIFLAPINVT
Mb0345c|M.bovis_AF2122/97 GAILRPLGQPANEIIETTALLLHIGVMLAFLILVLHSKHLHIFLAPINVT
Rv0338c|M.tuberculosis_H37Rv GAILRPLGQPANEIIETTALLLHIGVMLAFLILVLHSKHLHIFLAPINVT
MAV_4817|M.avium_104 GAILRPLGQPANEYIETAALLAHIAVMLAFLIIVLHSKHMHIFTAPINVI
MLBr_02501|M.leprae_Br4923 AAVLYPLGQGANQIIETVALLLHIGVMLAFLLIVLHSKHLHIFLAPINVT
MSMEG_0690|M.smegmatis_MC2_155 AWILRPLGATANMWIETVALMGHIGVMLVFLLIVLHSKHLHIGLAPINVT
MAB_4293|M.abscessus_ATCC_1997 AQLLPESPIMVSVFAFIKMMSGGLFLLLVGRKLVWG-VAWHRFAAFFNIY
TH_2670|M.thermoresistible__bu --------------------------------------------------
Mflv_0278|M.gilvum_PYR-GCK FKRLPNG---LGPLLPVESKGELVDFEDP-AEDAVLGRGKIEDFTWKGYL
Mvan_0619|M.vanbaalenii_PYR-1 FKRMPNA---LGPLLPVEYKGELVDFEDP-AEDAVLGRGKIEDFTWKAYL
MUL_0574|M.ulcerans_Agy99 FKRLPDG---LGPLLPVEADGKPVDFENP-PDDAIFGRGKIEDFTWKGML
MMAR_0611|M.marinum_M FKRLPDG---LGPLLPVEADGKPVDFENP-PDDAIFGRGKIEDFTWKGML
Mb0345c|M.bovis_AF2122/97 FKRLPDG---LGPLLPLEADGKPIDFENP-SEDAVFGRGKIEDFTWKGML
Rv0338c|M.tuberculosis_H37Rv FKRLPDG---LGPLLPLEADGKPIDFENP-SEDAVFGRGKIEDFTWKGML
MAV_4817|M.avium_104 FKRLPNG---LGPLLPIEYDGKPIDFENP-PDDAVFGRGKVEDFSWKAML
MLBr_02501|M.leprae_Br4923 FKRLPDG---LGPLMPMESDGEPINFEDP-SEDAVFGRGKIEDFTWKAML
MSMEG_0690|M.smegmatis_MC2_155 FKRLPNG---LGPLLPMESNGEYIDFEDP-AEDAVFGKGKIEDFTWKGYL
MAB_4293|M.abscessus_ATCC_1997 FKRNADGSVALGAAKPMMSGGKVLEMESADPDVDAFGAGKVEDFSWKDLL
TH_2670|M.thermoresistible__bu --------------------------------------------------
Mflv_0278|M.gilvum_PYR-GCK DFTTCTECGRCQSQCPAWNTGKPLSPKLVIMNLRDHMFAKAPYFLDGKES
Mvan_0619|M.vanbaalenii_PYR-1 DMTTCTECGRCQSQCPAWNTGKPLSPKLVIMNLRDHLFAKAPYILGDKET
MUL_0574|M.ulcerans_Agy99 DFATCTECGRCQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGEK--
MMAR_0611|M.marinum_M DFATCTECGRCQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGEK--
Mb0345c|M.bovis_AF2122/97 DFATCTECGRCQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGQK--
Rv0338c|M.tuberculosis_H37Rv DFATCTECGRCQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGQK--
MAV_4817|M.avium_104 DFATCTECGRCQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGDKQS
MLBr_02501|M.leprae_Br4923 DFATCTECGRCQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGEK--
MSMEG_0690|M.smegmatis_MC2_155 DFTTCTECGRCQSQCPAWNTGKPLSPKLVIMNLRDHMFAKAPYILGEKPS
MAB_4293|M.abscessus_ATCC_1997 DVTTCTECGRCQSQCPAWNTGKPLSPKLLITSLRDHTYAKAPYLLAGE--
TH_2670|M.thermoresistible__bu --------------------------------------------------
Mflv_0278|M.gilvum_PYR-GCK PLENTPEGGLGEELRGEKHSEKHSHEHVPESGFERIPADSPLQATRPLVG
Mvan_0619|M.vanbaalenii_PYR-1 PLENTPEGGLGEELRGEKQSEEHSHEHVPESGFERIMGSGPEQATRPLVG
MUL_0574|M.ulcerans_Agy99 --TADLLEGLDLETAAG------EGHHVPESGFGRVPGDGPEQAARPLVG
MMAR_0611|M.marinum_M --TADPLEGLDLETAAE------EGHHVPESGFGRVPGDGPEQAARPLVG
Mb0345c|M.bovis_AF2122/97 --DASAGG----EAGHQ------EHHHVPESGFGRVPGHGPEQATRPLVG
Rv0338c|M.tuberculosis_H37Rv --DASAGG----EAGHQ------EHHHVPESGFGRVPGHGPEQATRPLVG
MAV_4817|M.avium_104 PLESTPEGGVGEELSGEK---HAEAHHVPESGFGRVMGSGPEQATRPLVG
MLBr_02501|M.leprae_Br4923 --TAEKLEGLNLETTKD------KSRHVPESGFGRVPGHGPEQATRPLVG
MSMEG_0690|M.smegmatis_MC2_155 PLESTPEGGLGEKARGEKHEQKHAHDHVPESGFERILGSGPEQALRPLVG
MAB_4293|M.abscessus_ATCC_1997 -------------------------------DKSKLSEAEIAEGERQLVG
TH_2670|M.thermoresistible__bu --------------------------------------------------
Mflv_0278|M.gilvum_PYR-GCK TLEEGGVIDPDVLWSCTTCGACVEQCPVDIEHIDHIVDMRRYQVMMESEF
Mvan_0619|M.vanbaalenii_PYR-1 TLEQGGVIDPDVLWSCTTCGACVEQCPVDIEHIDHIVDMRRYQVMMESEF
MUL_0574|M.ulcerans_Agy99 TAEQGGVIDPDVLWSCVSCGACVEQCPVDIEHIDHIVDMRRYQVMMESEF
MMAR_0611|M.marinum_M TAEQGGVIDPDVLWSCVSCGACVEQCPVDIEHIDHIVDMRRYQVMMESEF
Mb0345c|M.bovis_AF2122/97 TEEQGGVIDPDVLWSCVTCGACVEQCPVDIEHVDHIVDMRRYQVMMESEF
Rv0338c|M.tuberculosis_H37Rv TEEQGGVIDPDVLWSCVTCGACVEQCPVDIEHVDHIVDMRRYQVMMESEF
MAV_4817|M.avium_104 TEEQGGVIDPDVLWSCVTCGACVEQCPVDIEHVDHIVDMRRYQVMMESEF
MLBr_02501|M.leprae_Br4923 TAEQGGVIDPDVLWSCVTCGACVEQCPVDIEHIDHIIDMRRYQVMMESEF
MSMEG_0690|M.smegmatis_MC2_155 TEEQGGVIDPDVLWSCTNCGACVEQCPVDIEHIDHIVDMRRYQVMVESEF
MAB_4293|M.abscessus_ATCC_1997 G--EGAVIDHEVLWSCTTCGACVEQCPVDIEHVDHIIDMRRYQVLIESEF
TH_2670|M.thermoresistible__bu --------------------------------------------------
Mflv_0278|M.gilvum_PYR-GCK PGELGVLFKNLETKGNPWGQNSKDRTNWIDEVDFDVPVFGKDVDSFEGYE
Mvan_0619|M.vanbaalenii_PYR-1 PGELGVLFKNLETKGNPWGQNAKDRTNWIDEVDFDVPVYGKDVESFDGFE
MUL_0574|M.ulcerans_Agy99 PSELSVLFKNLENKGNPWGQNASDRTNWIDEVDFDVPVYGEDVDSFDGYE
MMAR_0611|M.marinum_M PSELSVLFKNLENKGNPWGQNASDRTNWIDEVDFDVPVYGEDVDSFDGYE
Mb0345c|M.bovis_AF2122/97 PSELSVLFKNLETKGNPWGQNASDRTNWIDEVDFDVPVYGQDVDSFDGYE
Rv0338c|M.tuberculosis_H37Rv PSELSVLFKNLETKGNPWGQNASDRTNWIDEVDFDVPVYGQDVDSFDGYE
MAV_4817|M.avium_104 PSELSVLFKNLETKANPWGQNASDRTNWIDEVDFDVPVYGEDVDSFDGYE
MLBr_02501|M.leprae_Br4923 PSELSTLFKNLETKGNPWGQNAGDRTNWIDEVDFDVPVYGEDVDSFDGYE
MSMEG_0690|M.smegmatis_MC2_155 PGELGVLFKNLETKGNPWGQNAKDRTNWIDEVDFDVPVYGEDVDSFDGFE
MAB_4293|M.abscessus_ATCC_1997 PGELAGLFKNLENKGNPWGQNAKDRLNWIEEVDFDVPVFGQDVDSFADFE
TH_2670|M.thermoresistible__bu --------------------------------------------------
Mflv_0278|M.gilvum_PYR-GCK YLFWVGCAGAYEDRAKKTTKAVAELLSAAGVKYLVLGEGETCNGDSARRS
Mvan_0619|M.vanbaalenii_PYR-1 YLFWVGCAGAYEDRAKKTTKAVAELLAAAGVKYLVLGEGETCNGDSARRS
MUL_0574|M.ulcerans_Agy99 YLFWVGCAGAYDDKAKKTTKAVAELLATAGVKFMVLGAGETCNGDSARRS
MMAR_0611|M.marinum_M YLFWVGCAGAYDDKAKKTTKAVAELLATAGVKFMVLGAGETCNGDSARRS
Mb0345c|M.bovis_AF2122/97 YLFWVGCAGAYDDKAKKTTKAVAELLAVAGVKYLVLGAGETCNGDSARRS
Rv0338c|M.tuberculosis_H37Rv YLFWVGCAGAYDDKAKKTTKAVAELLAVARVKYLVLGAGETCNGDSARRS
MAV_4817|M.avium_104 YLFWVGCAGAYDDKAKKTTKAVAELLAVAGVKYLVLGAGETCNGDSARRS
MLBr_02501|M.leprae_Br4923 YLFWVGCAGAYDDKAKKTTKAVAELLAIAGVKYLVLGTGETCNGDSAHRS
MSMEG_0690|M.smegmatis_MC2_155 YLFWVGCAGAYEDRAKKTTKAVAELLATAGVKFLVLGTGETCTGDSARRS
MAB_4293|M.abscessus_ATCC_1997 YLFWVGCAGAYEDRAKKTTKAVAELLALAGTKFLVLGADETCTGDSARRA
TH_2670|M.thermoresistible__bu --------------------------------------------------
Mflv_0278|M.gilvum_PYR-GCK GNEFLFQQLAAQNVETLNDLFSGIERVDRKVVVTCPHCFNTLGREYPQVG
Mvan_0619|M.vanbaalenii_PYR-1 GNEFLFQQLAAQNVETLGELFEGVERVDRKVVVTCPHCFNTLGREYPQLG
MUL_0574|M.ulcerans_Agy99 GNEFLFQQLAQQAIETLDGVFEGVETVDRKVVVTCPHCFNTLGKEYRQLG
MMAR_0611|M.marinum_M GNEFLFQQLAQQAIETLDGVFEGVETVDRKVVVTCPHCFNTLGKEYRQLG
Mb0345c|M.bovis_AF2122/97 GNEFLFQQLAQQAVETLDGLFEGVETVDRKIVVTCPHCFNTIGKEYRQLG
Rv0338c|M.tuberculosis_H37Rv GNEFLFQQLAQQAVETLDGLFEGVETVDRKIVVTCPHCFNTIGKEYRQLG
MAV_4817|M.avium_104 GNEFLFQQLAAQAVETLDGVFEGVETVDRKIVVTCPHCFNTLGREYRQLG
MLBr_02501|M.leprae_Br4923 GNEFLFQQLAAQAVEILDGLFEGVNSVDRKIVVTCPHCFNTIGKEYRQLG
MSMEG_0690|M.smegmatis_MC2_155 GNEFLFQQLAAQNVETINELFEGVETVDRKIVVTCPHCFNTIGREYPQLG
MAB_4293|M.abscessus_ATCC_1997 GNEFLFQQLAMQNIELLNSVFEGVEQKQRKIVVTCAHCFNALGNEYPQVG
TH_2670|M.thermoresistible__bu --------------------------------------------------
Mflv_0278|M.gilvum_PYR-GCK GNYTVLHHTQLLNRLVRDKKLVPVKSTDGSPNGQDITYHDPCYLGRHNKE
Mvan_0619|M.vanbaalenii_PYR-1 GNYTVLHHTQLLNRLVRDKKLVPVKSTD---NGQDITYHDPCYLGRHNKE
MUL_0574|M.ulcerans_Agy99 SNYSVLHHTQLLNRLIRDKKLVPVTPVS-----QDVTYHDPCYLGRHNKV
MMAR_0611|M.marinum_M SNYSVLHHTQLLNRLIRDKKLVPVTPVS-----QDVTYHDPCYLGRHNKV
Mb0345c|M.bovis_AF2122/97 ANYTVLHHTQLLNRLVRDKRLVPVTPVS-----QDITYHDPCYLGRHNKV
Rv0338c|M.tuberculosis_H37Rv ANYTVLHHTQLLNRLVRDKRLVPVTPVS-----QDITYHDPCYLGRHNKA
MAV_4817|M.avium_104 ANYTVLHHTQLLNRLIRDNKLVPVTPVS-----QDITYHDPCYLGRHNKV
MLBr_02501|M.leprae_Br4923 GNYTVLHHTQLLNWLVHDKKLVPVTPVS-----QDITYHDPCYLGRHNKV
MSMEG_0690|M.smegmatis_MC2_155 ANYSVVHHTQLLNRLVRDKKLVPVKSVSEQ-NGQPVTYHDPCFLGRHNKV
MAB_4293|M.abscessus_ATCC_1997 GDYQVVHHTQLLNRLVRDKKLVPVAPVS-----QDVTYHDPCYLGRHNKV
TH_2670|M.thermoresistible__bu -----------MFHVKHGRPQSPSIPDG----------------------
: : :.. * . .
Mflv_0278|M.gilvum_PYR-GCK YSAPRELIGASGAKLTEMPRHADRGLCCGAGGARMWMEEHIGKRVNTERT
Mvan_0619|M.vanbaalenii_PYR-1 YSAPRELIGASGATLTEMPRHADRGLCCGAGGARMWMEEHIGKRVNTERT
MUL_0574|M.ulcerans_Agy99 YEAPRELIGAAGANLAEMPRHAERSFCCGAGGARMWMEEHIGKRINHERV
MMAR_0611|M.marinum_M YEAPRELIGAAGANLAEMPRHAERSFCCGAGGARMWMEEHIGKRINHERV
Mb0345c|M.bovis_AF2122/97 YEAPRELIGAAGASLTEMPRHADRSFCCGAGGARMWMEEHIGKRINHERV
Rv0338c|M.tuberculosis_H37Rv YEAPRELIGAAGASLTEMPRHADRSFCCGAGGARMWMEEHIGKRINHERV
MAV_4817|M.avium_104 YEAPRELIGAAGANLTEMPRHAERSFCCGAGGARMWMEEHIGKRINHERV
MLBr_02501|M.leprae_Br4923 YEAPRELVRAAGANFTEMPRHAERSFCCGAGGARMWMEEHIGKRINHERV
MSMEG_0690|M.smegmatis_MC2_155 YEAPRELVEASGVTLKEMPRHADRGLCCGAGGARMWMEEHIGKRVNVERT
MAB_4293|M.abscessus_ATCC_1997 YTAPRELIGASGAAITEMPRHGERSMCCGAGGARMWMEEQLGKRINIDRV
TH_2670|M.thermoresistible__bu --IPPXXXXADGEKTGGAP--AAKGLSIAAG----------AKRP-----
* * * * . :.:. .** .**
Mflv_0278|M.gilvum_PYR-GCK EEAIDTGASAIATGCPFCRVMMTDGVDDVSATRDIEKVEVLDVAQLLLGS
Mvan_0619|M.vanbaalenii_PYR-1 EEAIDTGASAIATGCPFCRVMMTDGVDDVSAAREIEKVEVLDVAQLLLGS
MUL_0574|M.ulcerans_Agy99 DEAVATNASTIATACPFCRVMVTDGVNDRQEEAGRSGVEVLDVAQVLLGS
MMAR_0611|M.marinum_M DEALATNASTIATACPFCRVMVTDGVNDRQEEAGRSGVEVLDVAQVLLGS
Mb0345c|M.bovis_AF2122/97 DEALATDATAIATACPFCRVMVTDGVNDRQEEAGRSGVEVLDVAQVLLGS
Rv0338c|M.tuberculosis_H37Rv DEALATDATAIATACPFCRVMVTDGVNDRQEEAGRSGVEVLDVAQVLLGS
MAV_4817|M.avium_104 DEALATGAATVATACPFCRVMVTDGVNDRQEEAGRSGVEVLDVAQILLGS
MLBr_02501|M.leprae_Br4923 DEALATNATTIATACPFCRVMVTDGVNDRQEEAGRSGVEVLDVAQVLLGS
MSMEG_0690|M.smegmatis_MC2_155 EEAMDT-ASTIATGCPFCRVMITDGVDDVAASRNVEKAEVLDVAQLLLNS
MAB_4293|M.abscessus_ATCC_1997 DEALSTPASKIATGCPFCRVMLTDGVTARDD---SAAVEVVDVAQLLLES
TH_2670|M.thermoresistible__bu --------------------------------------------------
Mflv_0278|M.gilvum_PYR-GCK LDKST---FTLPEKGTAAKESEERAARIAAEAPAEVEAEEPE-----AAP
Mvan_0619|M.vanbaalenii_PYR-1 LDQSS---FTLPEKGTAAKEAEERAARVAAQAPAKAEESAIETEAEAKTA
MUL_0574|M.ulcerans_Agy99 LDREK---ATLPEKGTAAKEAEKRA-KTAPKAAAPAAPAPAP-----AEA
MMAR_0611|M.marinum_M LDREK---ATLPEKGTAAKEAEKRA-KAAPKAAAPAAPAPAP-----AEA
Mb0345c|M.bovis_AF2122/97 LDHDK---AQLPAKGTAAKQAQERAPKAAPKAAAPVTPVEAP-----AEA
Rv0338c|M.tuberculosis_H37Rv LDHDK---AQLPAKGTAAKQAQERAPKAAPKAAAPVTPVEAP-----AEA
MAV_4817|M.avium_104 LEYDK---ATLPEKGTAAKEAEKRAAQAPKATATVEAPAKET-----TKE
MLBr_02501|M.leprae_Br4923 LDYDK---AKLPAKGTAAAEITKTAGLSPAKPTESEAPAPEK-----STQ
MSMEG_0690|M.smegmatis_MC2_155 LDTSK---VTLPEKGTAAKESEKRAAARAEAEAKAEAAAPPV-----EEA
MAB_4293|M.abscessus_ATCC_1997 VGRTEDIRKALPAKGTAAAAAAERAATKTAEPEPVVAEEEAP-----ATT
TH_2670|M.thermoresistible__bu -----------GAKKTAP------AGQADSGTAETETPKPEP--------
* **. *
Mflv_0278|M.gilvum_PYR-GCK AEEAAPAEAKAGTATETKPVTGLGVAGGAKRPGAKK-TAAAPAEDKPAAA
Mvan_0619|M.vanbaalenii_PYR-1 AEPAEAAKSTAAADTESKPVTGLGLAGGAKRPGAKKPAAAEPAEDKP--A
MUL_0574|M.ulcerans_Agy99 PAKAAEASAAATAASPAAPAKGLGMAGGAKRPGAKKAAPAPAAETAAAEA
MMAR_0611|M.marinum_M PAKAAEAPAAATAASPAAPAKGLGMAGGAKRPGAKKAAPAPAAETAAAEA
Mb0345c|M.bovis_AF2122/97 P-----------------------------------QAPAP---------
Rv0338c|M.tuberculosis_H37Rv P-----------------------------------QAPAP---------
MAV_4817|M.avium_104 PAEAAP-KAEAAPAAPAAPVKGLGIAGGAKRPGAKKSAPAAEAKTEAP--
MLBr_02501|M.leprae_Br4923 A-------------------------------------------------
MSMEG_0690|M.smegmatis_MC2_155 APEAEAPAAPAAGGAEAKPVTGLGMAGAAKRPGAKKAAPAAEASAAPAAA
MAB_4293|M.abscessus_ATCC_1997 KAEAAAPAAEAKPVSGLGMATGAKRPGAKKTAAENSTAEASTATPTAEAA
TH_2670|M.thermoresistible__bu --------------------------------------------------
Mflv_0278|M.gilvum_PYR-GCK AAPAKGLGIAGGAKRPGAKKAAPAAEAAPAADAPAKAEPEVKGLGIAGGA
Mvan_0619|M.vanbaalenii_PYR-1 PAPAKGLGIAGGAKRPGAKKAAPAAGTTP---------------------
MUL_0574|M.ulcerans_Agy99 PAAPAKGLGMAAGAKKPGAKKAAAPTGET---------------------
MMAR_0611|M.marinum_M PAAPAKGLGMAAGAKKPGAKKAAAPTGET---------------------
Mb0345c|M.bovis_AF2122/97 --------------------------------------------------
Rv0338c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4817|M.avium_104 --------------------------------------------------
MLBr_02501|M.leprae_Br4923 --------------------------------------------------
MSMEG_0690|M.smegmatis_MC2_155 PAPAKG-----LGLAGGAKRPGAKKAAAP---------------------
MAB_4293|M.abscessus_ATCC_1997 PAAPVKGLGMAAGAKRPGAKKATAETSAATPPAASASPP-----------
TH_2670|M.thermoresistible__bu --------------------------------------------------
Mflv_0278|M.gilvum_PYR-GCK KRPGAKKAAPAVEAAPAADAPAKAEPEAKGLGIAGGAKRPGAKKASGTVV
Mvan_0619|M.vanbaalenii_PYR-1 --------APAAESAAAAEP-AKAEPEVKGLGIAGGAKRPGAKKQAAPAA
MUL_0574|M.ulcerans_Agy99 --------KPAEAAAPAAP--------VKGLGMASGAKRPGAKKAAPPAA
MMAR_0611|M.marinum_M --------KPAEAAAPAAPA-----APVKGLGMASGAKRPGAKKAAPPAA
Mb0345c|M.bovis_AF2122/97 -------------AAPAAP--------VKGLGMAAGAKRPGAKKAAP---
Rv0338c|M.tuberculosis_H37Rv -------------AAPAAP--------VKGLGMAAGAKRPGAKKAAP---
MAV_4817|M.avium_104 --------AEAKTEAPAAP--------AKGLGIAAGAKRPGAKKSAPAAQ
MLBr_02501|M.leprae_Br4923 -------------AASAAP--------AKGIRLAAGAKQPDAKKPVSQTT
MSMEG_0690|M.smegmatis_MC2_155 --------AAEAPAAPASDA-----PPVKGLGLAGGAKRPGAKKTAAAAP
MAB_4293|M.abscessus_ATCC_1997 --------ASQAPAAAAAPAP-----PVKGLGMAAGAKRPGAKKTAPAAP
TH_2670|M.thermoresistible__bu --------------------------EVKGLGIAAGARRPGARKATSKAD
.**: :*.**::*.*:*
Mflv_0278|M.gilvum_PYR-GCK QPPNVDPDKAEAGTESAGTADSDRGLDDAPKPEPEVKGLGIAAGARRPGA
Mvan_0619|M.vanbaalenii_PYR-1 --PAAAAPAATPAPEAP--AQPEAAAAAPAKPEPEVKGLGIAAGARRPGA
MUL_0574|M.ulcerans_Agy99 AAPEAAATAPAPE--------AAAAPAEPAAPAAPVKGLGIATGAKRPGA
MMAR_0611|M.marinum_M AAPEAAATASAPE--------AAAAPAEPAAPAAPVKGLGIATGAKRPGA
Mb0345c|M.bovis_AF2122/97 ------------------------TPAAPAAPAAPVKGLGIAAGAKRPGA
Rv0338c|M.tuberculosis_H37Rv ------------------------TPAAPAAPAAPVKGLGIAAGAKRPGA
MAV_4817|M.avium_104 APKTEAPKTEAPKTEAKTEAAGEAKTEAPAAPAAPVKGLGIAAGAKRPGA
MLBr_02501|M.leprae_Br4923 S----------------------AKATEAPAATVPVKGLGIAGGAKRPGA
MSMEG_0690|M.smegmatis_MC2_155 AEKPAATEAP-------------EASATPAAPAAPVKGLGLAAGAKRPGA
MAB_4293|M.abscessus_ATCC_1997 AAPAPEAAAVPSESE------APTATETSAVAEPPVKGLGIAAGARRPGA
TH_2670|M.thermoresistible__bu TARADTAKADTADT-------AAAXTQAPAQPEPEVKGLAIAPGARRPGA
.. . ****.:* **:****
Mflv_0278|M.gilvum_PYR-GCK KKKAPAAAPDS----------------APAAAPES---------------
Mvan_0619|M.vanbaalenii_PYR-1 KKAPAAPAAESTSAPAESAPAPAESAPAPAATPEP---------------
MUL_0574|M.ulcerans_Agy99 KKAPARAEAPSAAAPAQ---------PEPEATPEP---------------
MMAR_0611|M.marinum_M KKAPARAEAPAAAAPAQ---------PEPEATPEP---------------
Mb0345c|M.bovis_AF2122/97 KKTPPPAPG-LAEPAAQ---------PQPEAKPQP---------------
Rv0338c|M.tuberculosis_H37Rv KKTPPPAPG-LAEPAAQ---------PQPEAKPQP---------------
MAV_4817|M.avium_104 KKAAPKAEAPKAEAEAAKAEAPKPEAPKAEAESKP---------------
MLBr_02501|M.leprae_Br4923 KKSPD-----QAETPAP---------TESKSEAKP---------------
MSMEG_0690|M.smegmatis_MC2_155 KKTAAAPAEKPAAAETEAPAPAETAAPAEPAKPEPPVVGLGIAAGARRPG
MAB_4293|M.abscessus_ATCC_1997 KKAAPATESAPEP-------------AQPATAPEP---------------
TH_2670|M.thermoresistible__bu KKAPATPAPAPAEPAAP---------KQPEAS------------------
** . :
Mflv_0278|M.gilvum_PYR-GCK ------------APAAPSSNGSDSS-----KGDDRVVGDEAPVKGLGIAK
Mvan_0619|M.vanbaalenii_PYR-1 ------------EPAPEAPSSGASD-----NGDTRVVGDEPPVKGLGIAK
MUL_0574|M.ulcerans_Agy99 ------------EPASKQDGEPTP-----------PAAPAAPVKGLGMAR
MMAR_0611|M.marinum_M ------------EPASKQDGEPTP-----------PAAPAAPVKGLGMAR
Mb0345c|M.bovis_AF2122/97 ------------EPAAPPKPQTDGD----------PAAPAAPVKGLGIAR
Rv0338c|M.tuberculosis_H37Rv ------------EPAAPPKPQTDGD----------PAAPAAPVKGLGIAR
MAV_4817|M.avium_104 ------------EPAKPSNGEGGS-----------SKPSQPPVKGLGIAR
MLBr_02501|M.leprae_Br4923 ------------EPSDHADG----N----------PAPPTAPVKRLGITR
MSMEG_0690|M.smegmatis_MC2_155 AKKAAAKPAAAPAPAAEKPAEQAAEPEKPAEKPAEPEKPEPPVVGLGIKP
MAB_4293|M.abscessus_ATCC_1997 -----------TEPATSAPKDEAPET---------SSTPEPPVKGLGIAP
TH_2670|M.thermoresistible__bu ------------DTAGQAEQAGSAE-----------EKPQPPVKGLGIAK
.: .** **:
Mflv_0278|M.gilvum_PYR-GCK GARRPGKR-
Mvan_0619|M.vanbaalenii_PYR-1 GARRPGKR-
MUL_0574|M.ulcerans_Agy99 GARPPGKR-
MMAR_0611|M.marinum_M GARPPGKR-
Mb0345c|M.bovis_AF2122/97 GARPPGKR-
Rv0338c|M.tuberculosis_H37Rv GARPPGKR-
MAV_4817|M.avium_104 GARPPGKR-
MLBr_02501|M.leprae_Br4923 SARPPGKH-
MSMEG_0690|M.smegmatis_MC2_155 GAKRPGKR-
MAB_4293|M.abscessus_ATCC_1997 GARRPGRRN
TH_2670|M.thermoresistible__bu GARPPGKKR
.*: **::