For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
NRIWLRAIILTASSALLAGCQFGGLNSLPLPGTAGHGEGAYSVTVEMADVATLPQNSPVMVDDVTVGSVA GIVAVQRPDGSFYAAVKLDLDKNVLLPANAVAKVSQTSLLGSLHVELAPPTDRPPTGRLVDGSRITEANT DRFPTTEEVFSALGVVVNKGNVGALEEIIDETHQAVAGRQAQFVNLVPRLAELTAGLNRQVHDIIDALDG LNRVSAILARDKDNLGRALDTLPDAVRVLNQNRDHIVDAFAALKRLTMVTSHVLAETKVDFGEDLKDLYS IVKALNDDRKDFVTSLQLLLTFPFPNFGIKQAVRGDYLNVFTTFDLTLRRIGETFFTTAYFDPNMAHMDE ILNPPDFLIGELANLSGQAADPFKIPPGTASGQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3495c | lprN | - | 100% (384) | POSSIBLE MCE-FAMILY LIPOPROTEIN LPRN (MCE-FAMILY LIPOPROTEIN MCE4E) |
| M. tuberculosis H37Rv | Rv1970 | lprM | 7e-60 | 38.30% (342) | MCE-family lipoprotein LprM |
| M. tuberculosis H37Rv | Rv0173 | lprK | 2e-49 | 34.29% (350) | MCE-family lipoprotein LprK |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3525c | lprN | 0.0 | 100.00% (384) | MCE-family lipoprotein LprN |
| M. gilvum PYR-GCK | Mflv_1560 | - | 1e-135 | 63.93% (377) | virulence factor Mce family protein |
| M. leprae Br4923 | MLBr_02593 | lprK | 8e-46 | 31.33% (332) | putative lipoprotein |
| M. abscessus ATCC 19977 | MAB_4149c | - | 1e-118 | 54.97% (382) | MCE-family protein LprN |
| M. marinum M | MMAR_4983 | lprN | 0.0 | 84.03% (382) | MCE family lipoprotein LprN |
| M. avium 104 | MAV_0661 | - | 1e-180 | 82.15% (381) | virulence factor Mce family protein |
| M. smegmatis MC2 155 | MSMEG_5896 | - | 1e-138 | 64.46% (377) | virulence factor Mce family protein |
| M. thermoresistible (build 8) | TH_1933 | lprN | 1e-143 | 65.71% (385) | POSSIBLE MCE-FAMILY LIPOPROTEIN LPRN (MCE-FAMILY LIPOPROTEIN |
| M. ulcerans Agy99 | MUL_4058 | lprN | 0.0 | 83.77% (382) | MCE family lipoprotein LprN |
| M. vanbaalenii PYR-1 | Mvan_5198 | - | 1e-136 | 63.66% (377) | virulence factor Mce family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3495c|M.tuberculosis_H37Rv -----------MNRIWLRAIILTA-SSALLAGCQFGGLNSLPLPGTAGHG
Mb3525c|M.bovis_AF2122/97 -----------MNRIWLRAIILTA-SSALLAGCQFGGLNSLPLPGTAGHG
MMAR_4983|M.marinum_M -----------MSRIWIRSSVFVA-FSALLAGCQYGGLNSLPMPGTAGHG
MUL_4058|M.ulcerans_Agy99 -----------MSRIWIRSSVFVA-FSALLAGCQYGGLNSLPMPGTAGHG
MAV_0661|M.avium_104 --------------MWLRAGGLAT-GSMLLAGCQFGGLNSLAMPGTAGHG
Mflv_1560|M.gilvum_PYR-GCK --------------MIRRVLGVSS-VALLLSGCQFGGLNSLNMPGTAGHG
Mvan_5198|M.vanbaalenii_PYR-1 --------------MIRRVLGLSS-IPLLLAGCQFGGLNSLNMPGTAGHG
MSMEG_5896|M.smegmatis_MC2_155 ----------------MRTLAIGS-GAVLLAGCQFGGLNSLNMPGTAGHG
TH_1933|M.thermoresistible__bu ----MTEMRNTLRRSAVRAVAIVS-GAALLAGCQFGGLNSLNLPGTAGHG
MAB_4149c|M.abscessus_ATCC_199 -----------MSRNVLRAAVMGVGVAVVVSGCQFNGLNSLNLPGTAGHG
MLBr_02593|M.leprae_Br4923 MRRAMSVVHTSRVRHQTWRGLVMLVAALLLSSCGWRGISNVSIPGGPGSG
. . :::.* : *:..: :** .* *
Rv3495c|M.tuberculosis_H37Rv EGAYSVTVEMADVATLPQNSPVMVDDVTVGSVAGIVAVQRPDGSFYAAVK
Mb3525c|M.bovis_AF2122/97 EGAYSVTVEMADVATLPQNSPVMVDDVTVGSVAGIVAVQRPDGSFYAAVK
MMAR_4983|M.marinum_M GGAYSVTVEMPDVATLPQNSPVMVDEVTVGSVSGINAVQRPDGSFYAAVK
MUL_4058|M.ulcerans_Agy99 GGAYSVTVEMPDVATLPQNSPVMVDEVTVGSVSGINAVQRPDGSFYAAVK
MAV_0661|M.avium_104 SGAYSITVELPDVATLPQNSPVMVDDVTVGSVAGISAEQRSDGSFYAAVK
Mflv_1560|M.gilvum_PYR-GCK SGSFDVSVQLPDVSTLPQNSPVMVDDVTVGSVSGVEAVQREDGTFFAEVQ
Mvan_5198|M.vanbaalenii_PYR-1 NGSYTISVQLPDVSTLPQNSPVMVDDVTVGSVSGVDAVQRPDGTFFAELQ
MSMEG_5896|M.smegmatis_MC2_155 PGSFKITVQLPDVATLPQNSPVMIDDVTVGSVSGIDAVQRPDGTFFAAVQ
TH_1933|M.thermoresistible__bu PGSYVVTVDVPDIATLPQNSPVMIDDVTVGSVSGIDAVQRPDGSFYAAVQ
MAB_4149c|M.abscessus_ATCC_199 SRSYTVTVELPDVTTLPQNSPVMVDDVTVGSVSGIDAFQKPDGSWYAGVK
MLBr_02593|M.leprae_Br4923 KGAYTIYVQVPDTLAINGNSKVMVADVTVGSIRAINLKN-----WVATLT
:: : *::.* :: ** **: :*****: .: : : * :
Rv3495c|M.tuberculosis_H37Rv LDLDKNVLLPANAVAKVSQTSLLGSLHVELAPP-TDRPPTGRLVDGSRIT
Mb3525c|M.bovis_AF2122/97 LDLDKNVLLPANAVAKVSQTSLLGSLHVELAPP-TDRPPTGRLVDGSRIT
MMAR_4983|M.marinum_M LALDKNVVLPANATAKVSQTSLLGSLHIELAAP-TDKPAEGRLADGSRIP
MUL_4058|M.ulcerans_Agy99 LALDKNVVLPANATAKVSQTSLLGSLHIELAAP-TDKPAEGRLADGSRIP
MAV_0661|M.avium_104 LALDKNVVLPANSTATVAQTSLLGSMHIDLNRP-KDRPAVGRLTDGSKIA
Mflv_1560|M.gilvum_PYR-GCK LSLDGNVKLPANATAKVAQTSLLGSQHIELAPP-ADGSGTGELVEGSRIP
Mvan_5198|M.vanbaalenii_PYR-1 LSLDGNVKLPANATARVAQTSLLGSQHLELAAP-ADGSGTGTLAEGSQIP
MSMEG_5896|M.smegmatis_MC2_155 LSLDGDVKLPANAVARVAQTSLLGSQHVELSEP-VGKPPEGELREGSNIS
TH_1933|M.thermoresistible__bu LSLDGHVRMPANSRVKIAQTSLLGSQHVELSPPPAGVAPVGELRDGSHIE
MAB_4149c|M.abscessus_ATCC_199 VSLEPEVHLPANAVAKVAQTSLLGSQHIELAAP-VGEPAVGKLTGGATIP
MLBr_02593|M.leprae_Br4923 LGLNKDVQLPKNTTAKIGQTSLLGSQHVELAAP--ANPSLELLKNGDTIP
: *: .* :* *: . :.******* *::* * . * * *
Rv3495c|M.tuberculosis_H37Rv EANTDRFPTTEEVFSALGVVVNKGNVGALEEIIDETHQAVAGRQAQFVNL
Mb3525c|M.bovis_AF2122/97 EANTDRFPTTEEVFSALGVVVNKGNVGALEEIIDETHQAVAGRQAQFVNL
MMAR_4983|M.marinum_M ESHTGRSPTTEEVFSALGVVVNKGNVGALEDITDEVYQAVAGRQGQFVDL
MUL_4058|M.ulcerans_Agy99 ESHTGRSPTTEEVFSALGVVVNKGNVGALEDITDEVYQAVAGRQGQFVDL
MAV_0661|M.avium_104 EANTGRYPTTEEVLSALGVVVNKGNVGALEEITDETYRAVAGRQDQFVDL
Mflv_1560|M.gilvum_PYR-GCK IDNTANYPTTEQVLSSLGVVVNKGNLGALQDITDETYNAVVGRSGTFEGL
Mvan_5198|M.vanbaalenii_PYR-1 IERTGNYPTTEQVLSSLGVVVNKGNLGALQDITDETYNAVVGRSGTFADL
MSMEG_5896|M.smegmatis_MC2_155 LDDAGRYPTTEEVLSSLGVVVNKGNLGALQDITDEVYAAVAGRSGSFADL
TH_1933|M.thermoresistible__bu LDADSRYPTTEEVLSSLGMVVNKGNLASLQDLTDEVYAAVAGRSMDFADL
MAB_4149c|M.abscessus_ATCC_199 LSRTGKYPSTEEVLSALSVVVNKGNLGALQDITDETYNLFKGRTGNLTQV
MLBr_02593|M.leprae_Br4923 LKNSSVFPTTEQTLASLSLILRGGGIPNLETLTNEVFNIFHGRADQIHAF
*:**:.:::*.:::. *.: *: : :*.. . ** : .
Rv3495c|M.tuberculosis_H37Rv VPRLAELTAGLNRQVHDIIDALDGLNRVSAILARDKDNLGRALDTLPDAV
Mb3525c|M.bovis_AF2122/97 VPRLAELTAGLNRQVHDIIDALDGLNRVSAILARDKDNLGRALDTLPDAV
MMAR_4983|M.marinum_M VPRLAELTAGLNKQVDDIIGAVDGLNRFSAILARDKDNLGRALDTLPDAL
MUL_4058|M.ulcerans_Agy99 VPRLAELTAGLNKQVDDIIGAVDGLNRFSAILARDKDNLGRALDTLPDAL
MAV_0661|M.avium_104 VPRLAELTSGLNRQVNDIIDAVDGLNRFSASLARDKDNLGRALDTLPEAI
Mflv_1560|M.gilvum_PYR-GCK IPRLAELTDSLDRQTGDIIAAAEGLNRFAGILAGSKDSLGRTLDTLPEAL
Mvan_5198|M.vanbaalenii_PYR-1 IPRLAELTASLDRQTDDIIAAAEGLNRFAGILARSKDSLGRTLDTLPEAL
MSMEG_5896|M.smegmatis_MC2_155 VPRLAELTASLDAQTDDIIAAADGLNRFASVLARSSDSLGRTLDTLPAAL
TH_1933|M.thermoresistible__bu VPRLAELTRALDQQTDDIIAAAEGIDRFAALLADSTDSLGRTLDTLPGAL
MAB_4149c|M.abscessus_ATCC_199 LPKLATLISSLNSQRDDIISAIEGIDKFSRVLAEHKESLGRAIDSIEPAL
MLBr_02593|M.leprae_Br4923 LTKLDTFASQLNQQRDDITHAIDSTNRLLTYVGGRSDVLDQILTDIPPLI
:.:* : *: * ** * :. ::. :. .: *.: : : :
Rv3495c|M.tuberculosis_H37Rv RVLNQNRDHIVDAFAALKRLTMVTSHVLAETKVDFGEDLKDLYSIVKALN
Mb3525c|M.bovis_AF2122/97 RVLNQNRDHIVDAFAALKRLTMVTSHVLAETKVDFGEDLKDLYSIVKALN
MMAR_4983|M.marinum_M RVLNKNRGNIVEAFSSLKRLAMVTSNVLSKTKVDFAEDLKGLYSVVKALN
MUL_4058|M.ulcerans_Agy99 RVLNKNRGNIVEAFSSLKGLAMVTSNVLSKTKVDFAEDLKGLYSVVKALN
MAV_0661|M.avium_104 RVLNKNRDHIVEAFSALHKLADVTSHILAKTKVDFAADLKDLYAAVKALN
Mflv_1560|M.gilvum_PYR-GCK EVLNDNRAQLVDAFTALRSFAEVASRVLQETKDDFAADFKDLFPVIKALN
Mvan_5198|M.vanbaalenii_PYR-1 QVLNDNRAQIVDAFTALRSFATVASRVLQETKDDFAADFKDLFPVIKALN
MSMEG_5896|M.smegmatis_MC2_155 KVLNDSRTNIVDAFTALRSFAEVGARILSETKDDFAADFKDLYAVVKELN
TH_1933|M.thermoresistible__bu RVLNENRANIVDTFAALQRFANVAAHVLAETKDDFAADMKDLYPVIKAVN
MAB_4149c|M.abscessus_ATCC_199 KVLNENRANIIEAFRSVGNLAKITDRVLRTTKDDIVADLKGLYPVVRALA
MLBr_02593|M.leprae_Br4923 KHFADTKNLLINAVGSVGQLSQAVDQYLSEARGPLHTDLQALACPLRELG
. : ..: ::::. :: :: . * :: : *:: * :: :
Rv3495c|M.tuberculosis_H37Rv DDRKDFVTSLQLLLTFPFPNFGIKQAVRGDYLNVFTTFDLTLRRIGETFF
Mb3525c|M.bovis_AF2122/97 DDRKDFVTSLQLLLTFPFPNFGIKQAVRGDYLNVFTTFDLTLRRIGETFF
MMAR_4983|M.marinum_M DNRKDFVSSLQLLLTFPFPNFGIKQAVRGDYLNVFTTFDLTLRRIGETFF
MUL_4058|M.ulcerans_Agy99 DNRKDFVSSLQLLLTFPFPNFGIKQAVRGDYLNVFTTFDLTLRRIGETFF
MAV_0661|M.avium_104 DNRRNFVTSLQLLLTFPFPNFGIKQAVRGDYLNVFTTFDLTLRRLGETFF
Mflv_1560|M.gilvum_PYR-GCK DNADYFIKDLEFLPTFPFHYKYLRNAVRGDYLNVYTTFDLTLRRVGESVF
Mvan_5198|M.vanbaalenii_PYR-1 DNADFFIKDLEFLPTFPFHYKYLRNAVRGDYLNVYTTFDLTLRRVGESVF
MSMEG_5896|M.smegmatis_MC2_155 DHVDYLIKDLELLPTFPFHYKYLRNAVRGDYLNVFATFDLTLRRTGESVF
TH_1933|M.thermoresistible__bu DNRADFVTGLDLLPTFPFTTKFLRRAVRGDYLNVFTTFDLTLRRIGESIF
MAB_4149c|M.abscessus_ATCC_199 ENRDVLIDSLDLLPTFPFSTKYLRNAVRGDYLNVFVTFDLTARRLGETLF
MLBr_02593|M.leprae_Br4923 RGAPYFIGAMKLILTQPYDVDTVPKIMRGDYQNVSLTLDVTYSAMDNAVL
:: :.:: * *: : . :**** ** *:*:* .::.:
Rv3495c|M.tuberculosis_H37Rv TTA-YFDPNMAHMDEILNPPDFLIGELANLSGQAADPFKIPPGTASGQ--
Mb3525c|M.bovis_AF2122/97 TTA-YFDPNMAHMDEILNPPDFLIGELANLSGQAADPFKIPPGTASGQ--
MMAR_4983|M.marinum_M TTA-YFDPNMAHMDEIVNPPNFLLGEMANLSGQAADPFKIPAGTASQ---
MUL_4058|M.ulcerans_Agy99 TTA-YFDPNMAHMDEIVNPPNFLLGEMANLSGQAADPFKIPAGTASQ---
MAV_0661|M.avium_104 TTA-YFDPNMAHMNEILNPPDFLVGEMANLSGQAADPFKIPPGTASGQ--
Mflv_1560|M.gilvum_PYR-GCK TTSLGLDPNMKRMNEIVNPPDFLTGAMANLSGQAADPFKIPPGTATQHEG
Mvan_5198|M.vanbaalenii_PYR-1 TTSLGLDPNMKRMSEVVNPPDFLTGAVANLSGQAADPFKIPPGTATQHEG
MSMEG_5896|M.smegmatis_MC2_155 TTS-GFDPNMKHMSEVLNPPEFLTGALANLSGQAADPFKIPPGTATQHEG
TH_1933|M.thermoresistible__bu TTS-PFDPNMAHLHEVVNPPDWLIGQQANLSGQAADPFKIPPGTASGQEE
MAB_4149c|M.abscessus_ATCC_199 TTS-FFDPNMQHFNDVVNPPEWLIGSMANLNGKETSPFDLPAPAAPQGGG
MLBr_02593|M.leprae_Br4923 TGTGLSGALRALEQSFGRDPETMIPDVRYTTNPNDAPGGPLVERADRRC-
* : .. .. . *: : .. * *
Rv3495c|M.tuberculosis_H37Rv ---
Mb3525c|M.bovis_AF2122/97 ---
MMAR_4983|M.marinum_M ---
MUL_4058|M.ulcerans_Agy99 ---
MAV_0661|M.avium_104 ---
Mflv_1560|M.gilvum_PYR-GCK AP-
Mvan_5198|M.vanbaalenii_PYR-1 AP-
MSMEG_5896|M.smegmatis_MC2_155 P--
TH_1933|M.thermoresistible__bu PIS
MAB_4149c|M.abscessus_ATCC_199 R--
MLBr_02593|M.leprae_Br4923 ---