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SRIWIRSSVFVAFSALLAGCQYGGLNSLPMPGTAGHGGGAYSVTVEMPDVATLPQNSPVMVDEVTVGSVS GINAVQRPDGSFYAAVKLALDKNVVLPANATAKVSQTSLLGSLHIELAAPTDKPAEGRLADGSRIPESHT GRSPTTEEVFSALGVVVNKGNVGALEDITDEVYQAVAGRQGQFVDLVPRLAELTAGLNKQVDDIIGAVDG LNRFSAILARDKDNLGRALDTLPDALRVLNKNRGNIVEAFSSLKRLAMVTSNVLSKTKVDFAEDLKGLYS VVKALNDNRKDFVSSLQLLLTFPFPNFGIKQAVRGDYLNVFTTFDLTLRRIGETFFTTAYFDPNMAHMDE IVNPPNFLLGEMANLSGQAADPFKIPAGTASQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4983 | lprN | - | 100% (383) | MCE family lipoprotein LprN |
| M. marinum M | MMAR_2886 | lprM | 4e-67 | 39.78% (367) | MCE family lipoprotein LprM |
| M. marinum M | MMAR_4055 | lprM_1 | 2e-62 | 38.29% (350) | MCE family lipoprotein LprM |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3525c | lprN | 0.0 | 84.03% (382) | MCE-family lipoprotein LprN |
| M. gilvum PYR-GCK | Mflv_1560 | - | 1e-138 | 66.58% (368) | virulence factor Mce family protein |
| M. tuberculosis H37Rv | Rv3495c | lprN | 0.0 | 84.03% (382) | MCE-family lipoprotein LprN |
| M. leprae Br4923 | MLBr_02593 | lprK | 5e-50 | 33.13% (332) | putative lipoprotein |
| M. abscessus ATCC 19977 | MAB_4149c | - | 1e-131 | 59.90% (384) | MCE-family protein LprN |
| M. avium 104 | MAV_0661 | - | 1e-178 | 81.53% (379) | virulence factor Mce family protein |
| M. smegmatis MC2 155 | MSMEG_5896 | - | 1e-143 | 66.67% (378) | virulence factor Mce family protein |
| M. thermoresistible (build 8) | TH_1933 | lprN | 1e-142 | 65.54% (383) | POSSIBLE MCE-FAMILY LIPOPROTEIN LPRN (MCE-FAMILY LIPOPROTEIN |
| M. ulcerans Agy99 | MUL_4058 | lprN | 0.0 | 99.74% (383) | MCE family lipoprotein LprN |
| M. vanbaalenii PYR-1 | Mvan_5198 | - | 1e-143 | 67.66% (368) | virulence factor Mce family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4983|M.marinum_M -----------MSRIWIRSSVFVA-FSALLAGCQYGGLNSLPMPGTAGHG
MUL_4058|M.ulcerans_Agy99 -----------MSRIWIRSSVFVA-FSALLAGCQYGGLNSLPMPGTAGHG
Mb3525c|M.bovis_AF2122/97 -----------MNRIWLRAIILTA-SSALLAGCQFGGLNSLPLPGTAGHG
Rv3495c|M.tuberculosis_H37Rv -----------MNRIWLRAIILTA-SSALLAGCQFGGLNSLPLPGTAGHG
MAV_0661|M.avium_104 --------------MWLRAGGLAT-GSMLLAGCQFGGLNSLAMPGTAGHG
Mflv_1560|M.gilvum_PYR-GCK --------------MIRRVLGVSS-VALLLSGCQFGGLNSLNMPGTAGHG
Mvan_5198|M.vanbaalenii_PYR-1 --------------MIRRVLGLSS-IPLLLAGCQFGGLNSLNMPGTAGHG
MSMEG_5896|M.smegmatis_MC2_155 ----------------MRTLAIGS-GAVLLAGCQFGGLNSLNMPGTAGHG
TH_1933|M.thermoresistible__bu ----MTEMRNTLRRSAVRAVAIVS-GAALLAGCQFGGLNSLNLPGTAGHG
MAB_4149c|M.abscessus_ATCC_199 -----------MSRNVLRAAVMGVGVAVVVSGCQFNGLNSLNLPGTAGHG
MLBr_02593|M.leprae_Br4923 MRRAMSVVHTSRVRHQTWRGLVMLVAALLLSSCGWRGISNVSIPGGPGSG
. . :::.* : *:..: :** .* *
MMAR_4983|M.marinum_M GGAYSVTVEMPDVATLPQNSPVMVDEVTVGSVSGINAVQRPDGSFYAAVK
MUL_4058|M.ulcerans_Agy99 GGAYSVTVEMPDVATLPQNSPVMVDEVTVGSVSGINAVQRPDGSFYAAVK
Mb3525c|M.bovis_AF2122/97 EGAYSVTVEMADVATLPQNSPVMVDDVTVGSVAGIVAVQRPDGSFYAAVK
Rv3495c|M.tuberculosis_H37Rv EGAYSVTVEMADVATLPQNSPVMVDDVTVGSVAGIVAVQRPDGSFYAAVK
MAV_0661|M.avium_104 SGAYSITVELPDVATLPQNSPVMVDDVTVGSVAGISAEQRSDGSFYAAVK
Mflv_1560|M.gilvum_PYR-GCK SGSFDVSVQLPDVSTLPQNSPVMVDDVTVGSVSGVEAVQREDGTFFAEVQ
Mvan_5198|M.vanbaalenii_PYR-1 NGSYTISVQLPDVSTLPQNSPVMVDDVTVGSVSGVDAVQRPDGTFFAELQ
MSMEG_5896|M.smegmatis_MC2_155 PGSFKITVQLPDVATLPQNSPVMIDDVTVGSVSGIDAVQRPDGTFFAAVQ
TH_1933|M.thermoresistible__bu PGSYVVTVDVPDIATLPQNSPVMIDDVTVGSVSGIDAVQRPDGSFYAAVQ
MAB_4149c|M.abscessus_ATCC_199 SRSYTVTVELPDVTTLPQNSPVMVDDVTVGSVSGIDAFQKPDGSWYAGVK
MLBr_02593|M.leprae_Br4923 KGAYTIYVQVPDTLAINGNSKVMVADVTVGSIRAINLKN-----WVATLT
:: : *::.* :: ** **: :*****: .: : : * :
MMAR_4983|M.marinum_M LALDKNVVLPANATAKVSQTSLLGSLHIELAAP-TDKPAEGRLADGSRIP
MUL_4058|M.ulcerans_Agy99 LALDKNVVLPANATAKVSQTSLLGSLHIELAAP-TDKPAEGRLADGSRIP
Mb3525c|M.bovis_AF2122/97 LDLDKNVLLPANAVAKVSQTSLLGSLHVELAPP-TDRPPTGRLVDGSRIT
Rv3495c|M.tuberculosis_H37Rv LDLDKNVLLPANAVAKVSQTSLLGSLHVELAPP-TDRPPTGRLVDGSRIT
MAV_0661|M.avium_104 LALDKNVVLPANSTATVAQTSLLGSMHIDLNRP-KDRPAVGRLTDGSKIA
Mflv_1560|M.gilvum_PYR-GCK LSLDGNVKLPANATAKVAQTSLLGSQHIELAPP-ADGSGTGELVEGSRIP
Mvan_5198|M.vanbaalenii_PYR-1 LSLDGNVKLPANATARVAQTSLLGSQHLELAAP-ADGSGTGTLAEGSQIP
MSMEG_5896|M.smegmatis_MC2_155 LSLDGDVKLPANAVARVAQTSLLGSQHVELSEP-VGKPPEGELREGSNIS
TH_1933|M.thermoresistible__bu LSLDGHVRMPANSRVKIAQTSLLGSQHVELSPPPAGVAPVGELRDGSHIE
MAB_4149c|M.abscessus_ATCC_199 VSLEPEVHLPANAVAKVAQTSLLGSQHIELAAP-VGEPAVGKLTGGATIP
MLBr_02593|M.leprae_Br4923 LGLNKDVQLPKNTTAKIGQTSLLGSQHVELAAP--ANPSLELLKNGDTIP
: *: .* :* *: . :.******* *::* * . * * *
MMAR_4983|M.marinum_M ESHTGRSPTTEEVFSALGVVVNKGNVGALEDITDEVYQAVAGRQGQFVDL
MUL_4058|M.ulcerans_Agy99 ESHTGRSPTTEEVFSALGVVVNKGNVGALEDITDEVYQAVAGRQGQFVDL
Mb3525c|M.bovis_AF2122/97 EANTDRFPTTEEVFSALGVVVNKGNVGALEEIIDETHQAVAGRQAQFVNL
Rv3495c|M.tuberculosis_H37Rv EANTDRFPTTEEVFSALGVVVNKGNVGALEEIIDETHQAVAGRQAQFVNL
MAV_0661|M.avium_104 EANTGRYPTTEEVLSALGVVVNKGNVGALEEITDETYRAVAGRQDQFVDL
Mflv_1560|M.gilvum_PYR-GCK IDNTANYPTTEQVLSSLGVVVNKGNLGALQDITDETYNAVVGRSGTFEGL
Mvan_5198|M.vanbaalenii_PYR-1 IERTGNYPTTEQVLSSLGVVVNKGNLGALQDITDETYNAVVGRSGTFADL
MSMEG_5896|M.smegmatis_MC2_155 LDDAGRYPTTEEVLSSLGVVVNKGNLGALQDITDEVYAAVAGRSGSFADL
TH_1933|M.thermoresistible__bu LDADSRYPTTEEVLSSLGMVVNKGNLASLQDLTDEVYAAVAGRSMDFADL
MAB_4149c|M.abscessus_ATCC_199 LSRTGKYPSTEEVLSALSVVVNKGNLGALQDITDETYNLFKGRTGNLTQV
MLBr_02593|M.leprae_Br4923 LKNSSVFPTTEQTLASLSLILRGGGIPNLETLTNEVFNIFHGRADQIHAF
*:**:.:::*.:::. *.: *: : :*.. . ** : .
MMAR_4983|M.marinum_M VPRLAELTAGLNKQVDDIIGAVDGLNRFSAILARDKDNLGRALDTLPDAL
MUL_4058|M.ulcerans_Agy99 VPRLAELTAGLNKQVDDIIGAVDGLNRFSAILARDKDNLGRALDTLPDAL
Mb3525c|M.bovis_AF2122/97 VPRLAELTAGLNRQVHDIIDALDGLNRVSAILARDKDNLGRALDTLPDAV
Rv3495c|M.tuberculosis_H37Rv VPRLAELTAGLNRQVHDIIDALDGLNRVSAILARDKDNLGRALDTLPDAV
MAV_0661|M.avium_104 VPRLAELTSGLNRQVNDIIDAVDGLNRFSASLARDKDNLGRALDTLPEAI
Mflv_1560|M.gilvum_PYR-GCK IPRLAELTDSLDRQTGDIIAAAEGLNRFAGILAGSKDSLGRTLDTLPEAL
Mvan_5198|M.vanbaalenii_PYR-1 IPRLAELTASLDRQTDDIIAAAEGLNRFAGILARSKDSLGRTLDTLPEAL
MSMEG_5896|M.smegmatis_MC2_155 VPRLAELTASLDAQTDDIIAAADGLNRFASVLARSSDSLGRTLDTLPAAL
TH_1933|M.thermoresistible__bu VPRLAELTRALDQQTDDIIAAAEGIDRFAALLADSTDSLGRTLDTLPGAL
MAB_4149c|M.abscessus_ATCC_199 LPKLATLISSLNSQRDDIISAIEGIDKFSRVLAEHKESLGRAIDSIEPAL
MLBr_02593|M.leprae_Br4923 LTKLDTFASQLNQQRDDITHAIDSTNRLLTYVGGRSDVLDQILTDIPPLI
:.:* : *: * ** * :. ::. :. .: *.: : : :
MMAR_4983|M.marinum_M RVLNKNRGNIVEAFSSLKRLAMVTSNVLSKTKVDFAEDLKGLYSVVKALN
MUL_4058|M.ulcerans_Agy99 RVLNKNRGNIVEAFSSLKGLAMVTSNVLSKTKVDFAEDLKGLYSVVKALN
Mb3525c|M.bovis_AF2122/97 RVLNQNRDHIVDAFAALKRLTMVTSHVLAETKVDFGEDLKDLYSIVKALN
Rv3495c|M.tuberculosis_H37Rv RVLNQNRDHIVDAFAALKRLTMVTSHVLAETKVDFGEDLKDLYSIVKALN
MAV_0661|M.avium_104 RVLNKNRDHIVEAFSALHKLADVTSHILAKTKVDFAADLKDLYAAVKALN
Mflv_1560|M.gilvum_PYR-GCK EVLNDNRAQLVDAFTALRSFAEVASRVLQETKDDFAADFKDLFPVIKALN
Mvan_5198|M.vanbaalenii_PYR-1 QVLNDNRAQIVDAFTALRSFATVASRVLQETKDDFAADFKDLFPVIKALN
MSMEG_5896|M.smegmatis_MC2_155 KVLNDSRTNIVDAFTALRSFAEVGARILSETKDDFAADFKDLYAVVKELN
TH_1933|M.thermoresistible__bu RVLNENRANIVDTFAALQRFANVAAHVLAETKDDFAADMKDLYPVIKAVN
MAB_4149c|M.abscessus_ATCC_199 KVLNENRANIIEAFRSVGNLAKITDRVLRTTKDDIVADLKGLYPVVRALA
MLBr_02593|M.leprae_Br4923 KHFADTKNLLINAVGSVGQLSQAVDQYLSEARGPLHTDLQALACPLRELG
. : ..: ::::. :: :: . * :: : *:: * :: :
MMAR_4983|M.marinum_M DNRKDFVSSLQLLLTFPFPNFGIKQAVRGDYLNVFTTFDLTLRRIGETFF
MUL_4058|M.ulcerans_Agy99 DNRKDFVSSLQLLLTFPFPNFGIKQAVRGDYLNVFTTFDLTLRRIGETFF
Mb3525c|M.bovis_AF2122/97 DDRKDFVTSLQLLLTFPFPNFGIKQAVRGDYLNVFTTFDLTLRRIGETFF
Rv3495c|M.tuberculosis_H37Rv DDRKDFVTSLQLLLTFPFPNFGIKQAVRGDYLNVFTTFDLTLRRIGETFF
MAV_0661|M.avium_104 DNRRNFVTSLQLLLTFPFPNFGIKQAVRGDYLNVFTTFDLTLRRLGETFF
Mflv_1560|M.gilvum_PYR-GCK DNADYFIKDLEFLPTFPFHYKYLRNAVRGDYLNVYTTFDLTLRRVGESVF
Mvan_5198|M.vanbaalenii_PYR-1 DNADFFIKDLEFLPTFPFHYKYLRNAVRGDYLNVYTTFDLTLRRVGESVF
MSMEG_5896|M.smegmatis_MC2_155 DHVDYLIKDLELLPTFPFHYKYLRNAVRGDYLNVFATFDLTLRRTGESVF
TH_1933|M.thermoresistible__bu DNRADFVTGLDLLPTFPFTTKFLRRAVRGDYLNVFTTFDLTLRRIGESIF
MAB_4149c|M.abscessus_ATCC_199 ENRDVLIDSLDLLPTFPFSTKYLRNAVRGDYLNVFVTFDLTARRLGETLF
MLBr_02593|M.leprae_Br4923 RGAPYFIGAMKLILTQPYDVDTVPKIMRGDYQNVSLTLDVTYSAMDNAVL
:: :.:: * *: : . :**** ** *:*:* .::.:
MMAR_4983|M.marinum_M TTA-YFDPNMAHMDEIVNPPNFLLGEMANLSGQAADPFKIPAGTASQ---
MUL_4058|M.ulcerans_Agy99 TTA-YFDPNMAHMDEIVNPPNFLLGEMANLSGQAADPFKIPAGTASQ---
Mb3525c|M.bovis_AF2122/97 TTA-YFDPNMAHMDEILNPPDFLIGELANLSGQAADPFKIPPGTASGQ--
Rv3495c|M.tuberculosis_H37Rv TTA-YFDPNMAHMDEILNPPDFLIGELANLSGQAADPFKIPPGTASGQ--
MAV_0661|M.avium_104 TTA-YFDPNMAHMNEILNPPDFLVGEMANLSGQAADPFKIPPGTASGQ--
Mflv_1560|M.gilvum_PYR-GCK TTSLGLDPNMKRMNEIVNPPDFLTGAMANLSGQAADPFKIPPGTATQHEG
Mvan_5198|M.vanbaalenii_PYR-1 TTSLGLDPNMKRMSEVVNPPDFLTGAVANLSGQAADPFKIPPGTATQHEG
MSMEG_5896|M.smegmatis_MC2_155 TTS-GFDPNMKHMSEVLNPPEFLTGALANLSGQAADPFKIPPGTATQHEG
TH_1933|M.thermoresistible__bu TTS-PFDPNMAHLHEVVNPPDWLIGQQANLSGQAADPFKIPPGTASGQEE
MAB_4149c|M.abscessus_ATCC_199 TTS-FFDPNMQHFNDVVNPPEWLIGSMANLNGKETSPFDLPAPAAPQGGG
MLBr_02593|M.leprae_Br4923 TGTGLSGALRALEQSFGRDPETMIPDVRYTTNPNDAPGGPLVERADRRC-
* : .. .. . *: : .. * *
MMAR_4983|M.marinum_M ---
MUL_4058|M.ulcerans_Agy99 ---
Mb3525c|M.bovis_AF2122/97 ---
Rv3495c|M.tuberculosis_H37Rv ---
MAV_0661|M.avium_104 ---
Mflv_1560|M.gilvum_PYR-GCK AP-
Mvan_5198|M.vanbaalenii_PYR-1 AP-
MSMEG_5896|M.smegmatis_MC2_155 P--
TH_1933|M.thermoresistible__bu PIS
MAB_4149c|M.abscessus_ATCC_199 R--
MLBr_02593|M.leprae_Br4923 ---