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M. thermoresistible (build 8) TH_1933 (lprN)

annotation: POSSIBLE MCE-FAMILY LIPOPROTEIN LPRN (MCE-FAMILY LIPOPROTEIN MCE4E)
coordinates: 3772771 - 3773964
length: 398

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1933lprN-100% (398)POSSIBLE MCE-FAMILY LIPOPROTEIN LPRN (MCE-FAMILY LIPOPROTEIN MCE4E)
M. thermoresistible (build 8)TH_1737lprNe-12057.67% (378) POSSIBLE MCE-FAMILY LIPOPROTEIN LPRN (MCE-FAMILY LIPOPROTEIN
M. thermoresistible (build 8)TH_4336-5e-6738.18% (351) PUTATIVE MCE-family lipoprotein LprM_1

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3525clprN1e-14365.71% (385) MCE-family lipoprotein LprN
M. gilvum PYR-GCKMflv_1560-1e-15169.29% (381) virulence factor Mce family protein
M. tuberculosis H37RvRv3495clprN1e-14365.71% (385) MCE-family lipoprotein LprN
M. leprae Br4923MLBr_02593lprK5e-4529.50% (339) putative lipoprotein
M. abscessus ATCC 19977MAB_4149c-1e-12958.70% (385) MCE-family protein LprN
M. marinum MMMAR_4983lprN1e-14265.54% (383) MCE family lipoprotein LprN
M. avium 104MAV_0661-1e-14465.79% (380) virulence factor Mce family protein
M. smegmatis MC2 155MSMEG_5896-1e-16274.41% (383) virulence factor Mce family protein
M. ulcerans Agy99MUL_4058lprN1e-14165.27% (383) MCE family lipoprotein LprN
M. vanbaalenii PYR-1Mvan_5198-1e-15169.82% (381) virulence factor Mce family protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1560|M.gilvum_PYR-GCK          --------------MIRRVLGVSS-VALLLSGCQFGGLNSLNMPGTAGHG
Mvan_5198|M.vanbaalenii_PYR-1       --------------MIRRVLGLSS-IPLLLAGCQFGGLNSLNMPGTAGHG
MSMEG_5896|M.smegmatis_MC2_155      ----------------MRTLAIGS-GAVLLAGCQFGGLNSLNMPGTAGHG
TH_1933|M.thermoresistible__bu      ----MTEMRNTLRRSAVRAVAIVS-GAALLAGCQFGGLNSLNLPGTAGHG
Mb3525c|M.bovis_AF2122/97           -----------MNRIWLRAIILTA-SSALLAGCQFGGLNSLPLPGTAGHG
Rv3495c|M.tuberculosis_H37Rv        -----------MNRIWLRAIILTA-SSALLAGCQFGGLNSLPLPGTAGHG
MMAR_4983|M.marinum_M               -----------MSRIWIRSSVFVA-FSALLAGCQYGGLNSLPMPGTAGHG
MUL_4058|M.ulcerans_Agy99           -----------MSRIWIRSSVFVA-FSALLAGCQYGGLNSLPMPGTAGHG
MAV_0661|M.avium_104                --------------MWLRAGGLAT-GSMLLAGCQFGGLNSLAMPGTAGHG
MAB_4149c|M.abscessus_ATCC_199      -----------MSRNVLRAAVMGVGVAVVVSGCQFNGLNSLNLPGTAGHG
MLBr_02593|M.leprae_Br4923          MRRAMSVVHTSRVRHQTWRGLVMLVAALLLSSCGWRGISNVSIPGGPGSG
                                                         .    . :::.* : *:..: :** .* *

Mflv_1560|M.gilvum_PYR-GCK          SGSFDVSVQLPDVSTLPQNSPVMVDDVTVGSVSGVEAVQREDGTFFAEVQ
Mvan_5198|M.vanbaalenii_PYR-1       NGSYTISVQLPDVSTLPQNSPVMVDDVTVGSVSGVDAVQRPDGTFFAELQ
MSMEG_5896|M.smegmatis_MC2_155      PGSFKITVQLPDVATLPQNSPVMIDDVTVGSVSGIDAVQRPDGTFFAAVQ
TH_1933|M.thermoresistible__bu      PGSYVVTVDVPDIATLPQNSPVMIDDVTVGSVSGIDAVQRPDGSFYAAVQ
Mb3525c|M.bovis_AF2122/97           EGAYSVTVEMADVATLPQNSPVMVDDVTVGSVAGIVAVQRPDGSFYAAVK
Rv3495c|M.tuberculosis_H37Rv        EGAYSVTVEMADVATLPQNSPVMVDDVTVGSVAGIVAVQRPDGSFYAAVK
MMAR_4983|M.marinum_M               GGAYSVTVEMPDVATLPQNSPVMVDEVTVGSVSGINAVQRPDGSFYAAVK
MUL_4058|M.ulcerans_Agy99           GGAYSVTVEMPDVATLPQNSPVMVDEVTVGSVSGINAVQRPDGSFYAAVK
MAV_0661|M.avium_104                SGAYSITVELPDVATLPQNSPVMVDDVTVGSVAGISAEQRSDGSFYAAVK
MAB_4149c|M.abscessus_ATCC_199      SRSYTVTVELPDVTTLPQNSPVMVDDVTVGSVSGIDAFQKPDGSWYAGVK
MLBr_02593|M.leprae_Br4923          KGAYTIYVQVPDTLAINGNSKVMVADVTVGSIRAINLKN-----WVATLT
                                      :: : *::.*  ::  ** **: :*****: .:   :     : * : 

Mflv_1560|M.gilvum_PYR-GCK          LSLDGNVKLPANATAKVAQTSLLGSQHIELAPP-ADGSGTGELVEGSRIP
Mvan_5198|M.vanbaalenii_PYR-1       LSLDGNVKLPANATARVAQTSLLGSQHLELAAP-ADGSGTGTLAEGSQIP
MSMEG_5896|M.smegmatis_MC2_155      LSLDGDVKLPANAVARVAQTSLLGSQHVELSEP-VGKPPEGELREGSNIS
TH_1933|M.thermoresistible__bu      LSLDGHVRMPANSRVKIAQTSLLGSQHVELSPPPAGVAPVGELRDGSHIE
Mb3525c|M.bovis_AF2122/97           LDLDKNVLLPANAVAKVSQTSLLGSLHVELAPP-TDRPPTGRLVDGSRIT
Rv3495c|M.tuberculosis_H37Rv        LDLDKNVLLPANAVAKVSQTSLLGSLHVELAPP-TDRPPTGRLVDGSRIT
MMAR_4983|M.marinum_M               LALDKNVVLPANATAKVSQTSLLGSLHIELAAP-TDKPAEGRLADGSRIP
MUL_4058|M.ulcerans_Agy99           LALDKNVVLPANATAKVSQTSLLGSLHIELAAP-TDKPAEGRLADGSRIP
MAV_0661|M.avium_104                LALDKNVVLPANSTATVAQTSLLGSMHIDLNRP-KDRPAVGRLTDGSKIA
MAB_4149c|M.abscessus_ATCC_199      VSLEPEVHLPANAVAKVAQTSLLGSQHIELAAP-VGEPAVGKLTGGATIP
MLBr_02593|M.leprae_Br4923          LGLNKDVQLPKNTTAKIGQTSLLGSQHVELAAP--ANPSLELLKNGDTIP
                                    : *: .* :* *: . :.******* *::*  *    .    *  *  * 

Mflv_1560|M.gilvum_PYR-GCK          IDNTANYPTTEQVLSSLGVVVNKGNLGALQDITDETYNAVVGRSGTFEGL
Mvan_5198|M.vanbaalenii_PYR-1       IERTGNYPTTEQVLSSLGVVVNKGNLGALQDITDETYNAVVGRSGTFADL
MSMEG_5896|M.smegmatis_MC2_155      LDDAGRYPTTEEVLSSLGVVVNKGNLGALQDITDEVYAAVAGRSGSFADL
TH_1933|M.thermoresistible__bu      LDADSRYPTTEEVLSSLGMVVNKGNLASLQDLTDEVYAAVAGRSMDFADL
Mb3525c|M.bovis_AF2122/97           EANTDRFPTTEEVFSALGVVVNKGNVGALEEIIDETHQAVAGRQAQFVNL
Rv3495c|M.tuberculosis_H37Rv        EANTDRFPTTEEVFSALGVVVNKGNVGALEEIIDETHQAVAGRQAQFVNL
MMAR_4983|M.marinum_M               ESHTGRSPTTEEVFSALGVVVNKGNVGALEDITDEVYQAVAGRQGQFVDL
MUL_4058|M.ulcerans_Agy99           ESHTGRSPTTEEVFSALGVVVNKGNVGALEDITDEVYQAVAGRQGQFVDL
MAV_0661|M.avium_104                EANTGRYPTTEEVLSALGVVVNKGNVGALEEITDETYRAVAGRQDQFVDL
MAB_4149c|M.abscessus_ATCC_199      LSRTGKYPSTEEVLSALSVVVNKGNLGALQDITDETYNLFKGRTGNLTQV
MLBr_02593|M.leprae_Br4923          LKNSSVFPTTEQTLASLSLILRGGGIPNLETLTNEVFNIFHGRADQIHAF
                                           *:**:.:::*.:::. *.:  *: : :*..  . **   :  .

Mflv_1560|M.gilvum_PYR-GCK          IPRLAELTDSLDRQTGDIIAAAEGLNRFAGILAGSKDSLGRTLDTLPEAL
Mvan_5198|M.vanbaalenii_PYR-1       IPRLAELTASLDRQTDDIIAAAEGLNRFAGILARSKDSLGRTLDTLPEAL
MSMEG_5896|M.smegmatis_MC2_155      VPRLAELTASLDAQTDDIIAAADGLNRFASVLARSSDSLGRTLDTLPAAL
TH_1933|M.thermoresistible__bu      VPRLAELTRALDQQTDDIIAAAEGIDRFAALLADSTDSLGRTLDTLPGAL
Mb3525c|M.bovis_AF2122/97           VPRLAELTAGLNRQVHDIIDALDGLNRVSAILARDKDNLGRALDTLPDAV
Rv3495c|M.tuberculosis_H37Rv        VPRLAELTAGLNRQVHDIIDALDGLNRVSAILARDKDNLGRALDTLPDAV
MMAR_4983|M.marinum_M               VPRLAELTAGLNKQVDDIIGAVDGLNRFSAILARDKDNLGRALDTLPDAL
MUL_4058|M.ulcerans_Agy99           VPRLAELTAGLNKQVDDIIGAVDGLNRFSAILARDKDNLGRALDTLPDAL
MAV_0661|M.avium_104                VPRLAELTSGLNRQVNDIIDAVDGLNRFSASLARDKDNLGRALDTLPEAI
MAB_4149c|M.abscessus_ATCC_199      LPKLATLISSLNSQRDDIISAIEGIDKFSRVLAEHKESLGRAIDSIEPAL
MLBr_02593|M.leprae_Br4923          LTKLDTFASQLNQQRDDITHAIDSTNRLLTYVGGRSDVLDQILTDIPPLI
                                    :.:*  :   *: *  **  * :. ::.   :.  .: *.: :  :   :

Mflv_1560|M.gilvum_PYR-GCK          EVLNDNRAQLVDAFTALRSFAEVASRVLQETKDDFAADFKDLFPVIKALN
Mvan_5198|M.vanbaalenii_PYR-1       QVLNDNRAQIVDAFTALRSFATVASRVLQETKDDFAADFKDLFPVIKALN
MSMEG_5896|M.smegmatis_MC2_155      KVLNDSRTNIVDAFTALRSFAEVGARILSETKDDFAADFKDLYAVVKELN
TH_1933|M.thermoresistible__bu      RVLNENRANIVDTFAALQRFANVAAHVLAETKDDFAADMKDLYPVIKAVN
Mb3525c|M.bovis_AF2122/97           RVLNQNRDHIVDAFAALKRLTMVTSHVLAETKVDFGEDLKDLYSIVKALN
Rv3495c|M.tuberculosis_H37Rv        RVLNQNRDHIVDAFAALKRLTMVTSHVLAETKVDFGEDLKDLYSIVKALN
MMAR_4983|M.marinum_M               RVLNKNRGNIVEAFSSLKRLAMVTSNVLSKTKVDFAEDLKGLYSVVKALN
MUL_4058|M.ulcerans_Agy99           RVLNKNRGNIVEAFSSLKGLAMVTSNVLSKTKVDFAEDLKGLYSVVKALN
MAV_0661|M.avium_104                RVLNKNRDHIVEAFSALHKLADVTSHILAKTKVDFAADLKDLYAAVKALN
MAB_4149c|M.abscessus_ATCC_199      KVLNENRANIIEAFRSVGNLAKITDRVLRTTKDDIVADLKGLYPVVRALA
MLBr_02593|M.leprae_Br4923          KHFADTKNLLINAVGSVGQLSQAVDQYLSEARGPLHTDLQALACPLRELG
                                    . : ..:  ::::. ::  ::    . *  ::  :  *:: *   :: : 

Mflv_1560|M.gilvum_PYR-GCK          DNADYFIKDLEFLPTFPFHYKYLRNAVRGDYLNVYTTFDLTLRRVGESVF
Mvan_5198|M.vanbaalenii_PYR-1       DNADFFIKDLEFLPTFPFHYKYLRNAVRGDYLNVYTTFDLTLRRVGESVF
MSMEG_5896|M.smegmatis_MC2_155      DHVDYLIKDLELLPTFPFHYKYLRNAVRGDYLNVFATFDLTLRRTGESVF
TH_1933|M.thermoresistible__bu      DNRADFVTGLDLLPTFPFTTKFLRRAVRGDYLNVFTTFDLTLRRIGESIF
Mb3525c|M.bovis_AF2122/97           DDRKDFVTSLQLLLTFPFPNFGIKQAVRGDYLNVFTTFDLTLRRIGETFF
Rv3495c|M.tuberculosis_H37Rv        DDRKDFVTSLQLLLTFPFPNFGIKQAVRGDYLNVFTTFDLTLRRIGETFF
MMAR_4983|M.marinum_M               DNRKDFVSSLQLLLTFPFPNFGIKQAVRGDYLNVFTTFDLTLRRIGETFF
MUL_4058|M.ulcerans_Agy99           DNRKDFVSSLQLLLTFPFPNFGIKQAVRGDYLNVFTTFDLTLRRIGETFF
MAV_0661|M.avium_104                DNRRNFVTSLQLLLTFPFPNFGIKQAVRGDYLNVFTTFDLTLRRLGETFF
MAB_4149c|M.abscessus_ATCC_199      ENRDVLIDSLDLLPTFPFSTKYLRNAVRGDYLNVFVTFDLTARRLGETLF
MLBr_02593|M.leprae_Br4923          RGAPYFIGAMKLILTQPYDVDTVPKIMRGDYQNVSLTLDVTYSAMDNAVL
                                         ::  :.:: * *:    : . :**** **  *:*:*    .::.:

Mflv_1560|M.gilvum_PYR-GCK          TTSLGLDPNMKRMNEIVNPPDFLTGAMANLSGQAADPFKIPPGTATQHEG
Mvan_5198|M.vanbaalenii_PYR-1       TTSLGLDPNMKRMSEVVNPPDFLTGAVANLSGQAADPFKIPPGTATQHEG
MSMEG_5896|M.smegmatis_MC2_155      TTS-GFDPNMKHMSEVLNPPEFLTGALANLSGQAADPFKIPPGTATQHEG
TH_1933|M.thermoresistible__bu      TTS-PFDPNMAHLHEVVNPPDWLIGQQANLSGQAADPFKIPPGTASGQEE
Mb3525c|M.bovis_AF2122/97           TTA-YFDPNMAHMDEILNPPDFLIGELANLSGQAADPFKIPPGTASGQ--
Rv3495c|M.tuberculosis_H37Rv        TTA-YFDPNMAHMDEILNPPDFLIGELANLSGQAADPFKIPPGTASGQ--
MMAR_4983|M.marinum_M               TTA-YFDPNMAHMDEIVNPPNFLLGEMANLSGQAADPFKIPAGTASQ---
MUL_4058|M.ulcerans_Agy99           TTA-YFDPNMAHMDEIVNPPNFLLGEMANLSGQAADPFKIPAGTASQ---
MAV_0661|M.avium_104                TTA-YFDPNMAHMNEILNPPDFLVGEMANLSGQAADPFKIPPGTASGQ--
MAB_4149c|M.abscessus_ATCC_199      TTS-FFDPNMQHFNDVVNPPEWLIGSMANLNGKETSPFDLPAPAAPQGGG
MLBr_02593|M.leprae_Br4923          TGTGLSGALRALEQSFGRDPETMIPDVRYTTNPNDAPGGPLVERADRRC-
                                    * :   ..      .. . *: :       ..    *       *     

Mflv_1560|M.gilvum_PYR-GCK          AP-
Mvan_5198|M.vanbaalenii_PYR-1       AP-
MSMEG_5896|M.smegmatis_MC2_155      P--
TH_1933|M.thermoresistible__bu      PIS
Mb3525c|M.bovis_AF2122/97           ---
Rv3495c|M.tuberculosis_H37Rv        ---
MMAR_4983|M.marinum_M               ---
MUL_4058|M.ulcerans_Agy99           ---
MAV_0661|M.avium_104                ---
MAB_4149c|M.abscessus_ATCC_199      R--
MLBr_02593|M.leprae_Br4923          ---