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ATIAQRLRDDHGVAASESSVRRWIATHFAEEVARERVTVPRGPVDAGSEAQIDYGRLGMWFDPATARRVA VWAFVMVLAFSRHLFVRPVIRMDQTAWCACHVAAFEFFDGVPARLVCDNLRTGVDKPDLYDPQINRSYAE LASHYATLVDPARARKPKDKPRVERPMTYVRDSFWKGREFDSLAQMQQAAVTWSTEVAGLRYLRALEGAQ PLRMFEAVEQQALIALPPRAFELTSWSIGTVGVDTHLKVGKALYSVPWRLIGQRLHARTAGDVVQIFAGN DVVATHVRRPSGRSTDFSHYPPEKIAFHMRTPTWCRHTAELVGPASQQVIAEFMRDNAIHHLRSAQGVLG LRDKHGCDRLEAACARAIEVGDPSYRTIKGILVAGTEHAANEPTTSSPASTAGGVPARP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3428c | - | - | 100% (410) | POSSIBLE TRANSPOSASE |
| M. tuberculosis H37Rv | Rv2943 | - | 3e-06 | 27.41% (259) | IS1533 transposase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2968 | - | 3e-06 | 27.41% (259) | IS1533 transposase |
| M. gilvum PYR-GCK | Mflv_2877 | - | 1e-07 | 26.35% (334) | integrase catalytic subunit |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_3533 | - | 5e-06 | 25.53% (329) | transposase |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_4229 | - | 1e-52 | 35.66% (387) | PUTATIVE putative acyl-CoA synthase |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_3264 | - | 4e-16 | 27.33% (300) | transposase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2877|M.gilvum_PYR-GCK -----------MDIISAYQQLG-----SYRAAAAECGTTHRTVKKVVKKF
MAV_3533|M.avium_104 -----------MNIISAYHQVG-----SYRGAAELCGTTHKTVKRVIERA
Rv3428c|M.tuberculosis_H37Rv ------------------------------------------------MA
TH_4229|M.thermoresistible__bu MAFREVNVNEIREVLRLWLGVAGLPAPGLRTIAAHCGLDRKTVRRYVQAA
Mb2968|M.bovis_AF2122/97 ----MLTVEDWAEIRRLHRAEG----LPIKMIARVLGISKNTVKSALESN
Mvan_3264|M.vanbaalenii_PYR-1 -------MRSRVELFEKIRRDRRLEDLSIRELADRHGTHRRTVRQALEDA
Mflv_2877|M.gilvum_PYR-GCK EADQAGVPPLPRAERAHNYDAVADLVAERVDKSKGRISAKRLLPKARAAG
MAV_3533|M.avium_104 EAG--GAP--PREPRPRNLDAFTDLVATRVEKSHGKMSAKRMLPIARAAG
Rv3428c|M.tuberculosis_H37Rv TIAQRLRDDHG-----------------------------VAASESSVRR
TH_4229|M.thermoresistible__bu HAAGLRRDDDASVIDDGLIGAVAEAVRPVRPHGHGAAWEQLLAFEGQIRA
Mb2968|M.bovis_AF2122/97 QQPKYERAPQG---------SIVDAVEPRIRELLQAYPTMPATVIAERIG
Mvan_3264|M.vanbaalenii_PYR-1 VPPPRKVYPERPRPAIDEYVVVIDAWLIADEKAPRKQRHTARRVWQRLVA
Mflv_2877|M.gilvum_PYR-GCK YTGSD------------------------RNFRRLVAEAKALWRSENHRG
MAV_3533|M.avium_104 YQGSA------------------------RNFRRLVAEQKVLWRNANRHQ
Rv3428c|M.tuberculosis_H37Rv WIAT-----------------------------HFAEEVA---RERVTVP
TH_4229|M.thermoresistible__bu WVAGDGEQRPLTITKIHTLLARQGCVVPYRTLHRFASERCGFGRKGTTVR
Mb2968|M.bovis_AF2122/97 WERSIR------------------------VLSARVAELRPVYLPPDPAS
Mvan_3264|M.vanbaalenii_PYR-1 EHQAT---------------------CAEVTVSRYVARRRVELGLETREV
. .
Mflv_2877|M.gilvum_PYR-GCK R---RPAVWEPGEY-LVIDWAQAAPG-------LFLFCAVLAFSRWRFVR
MAV_3533|M.avium_104 R---RPAVWSPGDY-LVMDWAEAAPG-------LMVFCAVLAYSRWRFVR
Rv3428c|M.tuberculosis_H37Rv RGPVDAGSEAQIDYGRLGMWFDPATARR---VAVWAFVMVLAFSRHLFVR
TH_4229|M.thermoresistible__bu VADGDPGVECQIDFGYLGMLTDATDGRR---RKVHALIFTAVYSRHMFVW
Mb2968|M.bovis_AF2122/97 RTTYVAGEIAQCDFWFPPIELPVGFGQTRTAKQLPVLTMVCAYSRWLLAM
Mvan_3264|M.vanbaalenii_PYR-1 SIPQSHLPGAEAEVDFGEFYATIAGLVVK----CWMFVMRLSHSGKAFHV
: : .* :
Mflv_2877|M.gilvum_PYR-GCK FATDERASTTLALIAETLSAAGGVPAKVLADRMACLKGGVV-ANVVVPTP
MAV_3533|M.avium_104 FAADEKASTTLAMIAEALEAIGGVPAKILADRMGCLKGGVV-ANVVVPTP
Rv3428c|M.tuberculosis_H37Rv PVIRMDQTAWCACHVAAFEFFDGVPARLVCDNLRTGVDKPD-LYDPQINR
TH_4229|M.thermoresistible__bu LTYSQTLAAVIAGCQAAWAFFGGVFAVLIPDNLKPVIASAD-ALNPQFTR
Mb2968|M.bovis_AF2122/97 LLPSRCAEDLFAGWWRLIEALGAVPRVLVWD-GEGAIGRWR-GGRSELTT
Mvan_3264|M.vanbaalenii_PYR-1 AFATQAQEAFLEGHVLAFEYFGGVPGRIRYDNLKPAVIRVLKGRDRTESE
..* : * .
Mflv_2877|M.gilvum_PYR-GCK DYVRLASHYGFAPDFCHA--SDPQSKGIVENLCGYAQDDLAVPLLTEAAV
MAV_3533|M.avium_104 DYVRFASHYGFVPDFCHG--ADPQSKGIVENLCGYAQDDLAVPLLTEAAL
Rv3428c|M.tuberculosis_H37Rv SYAELASHYATLVDPARA--RKPKDKPRVERPMTYVRDSFWK--------
TH_4229|M.thermoresistible__bu GWLDYAGHGGFLTDPARV--RSPKDKPRVERVVQYVRRNFWD--------
Mb2968|M.bovis_AF2122/97 ECQAFRGTLAAKVLICRP--ADPEAKGLIERAHDYLERSFLP--------
Mvan_3264|M.vanbaalenii_PYR-1 RFTALRSHYGFDSFFCRPGIDGAHEKGGVEGEIGRFRRRHLVP-------
. . .: .. * :* .
Mflv_2877|M.gilvum_PYR-GCK TGTPIDLRDANAAAEVWCAEVNAAT--HSEICAIPDERLIT-ERELLAPL
MAV_3533|M.avium_104 AGEQVDLRALNAQAQLWCAEVNATV--HSEICAVPNDRLVD-ERTVLREL
Rv3428c|M.tuberculosis_H37Rv GREFDSLAQMQQAAVTWSTEVAGLRYLRALEGAQPLRMFEAVEQQALIAL
TH_4229|M.thermoresistible__bu GETFSSLDEAQHVATVWCERTAGTR-IHGTTCARPLEVFTAEEQPLLLAM
Mb2968|M.bovis_AF2122/97 GRVFASPADFNAQLGAWLALVNTRT--RRALGCAPTDRIGA-DRAAMLSL
Mvan_3264|M.vanbaalenii_PYR-1 VPKVASLAELNELIAAADVVDDDRV---ITGRPITIGAAFAIETTELMGL
. : . : : :
Mflv_2877|M.gilvum_PYR-GCK PSLRLQIGAPSVLRKVDRLSCVRYGSARYSVPTRLIGTTVAVVVDHGALC
MAV_3533|M.avium_104 PSLRPTIGSGSVRRKVDGLSCIRYGSARYSVPQRLVGATVAVVVDHGALI
Rv3428c|M.tuberculosis_H37Rv PPRAFELTSWSIG-TVGVDTHLKVGKALYSVPWRLIGQRLHARTAGDVVQ
TH_4229|M.thermoresistible__bu PG-VYDVPVFKAV-KVHRDFHAEVAKALYSLPECWIGTTLDVRADGELVK
Mb2968|M.bovis_AF2122/97 PPVAPATG-WCTSLRLPRDHYVRCDSNDYSVHPGVIGHRVLVRADLERVH
Mvan_3264|M.vanbaalenii_PYR-1 PAEVFDCARLLNA-RVDNRARVSVRQCFYSVPARYAGRRLPVRLAARTVE
* : . **: * : . :
Mflv_2877|M.gilvum_PYR-GCK LLEPATGVIVAEHELVAPGGVSILDEHYDGPRPAPDRGPRPKTTVEKQFC
MAV_3533|M.avium_104 LLEPATGVIVAEHELVSPGEVSILDEHYDGPRPAPSRGPRPKTQAEKRFC
Rv3428c|M.tuberculosis_H37Rv IFAGND--VVATHVRRPSG-RSTDFSHY--PPEKIAFHMRTPTWCRHTAE
TH_4229|M.thermoresistible__bu FYHRGT--LVKVHPRQPAGGRSTDRGDL--PEHKAGYALRDLAALIAACA
Mb2968|M.bovis_AF2122/97 VFCDGE--LVADHERIWAVHQTVS---------DPAHVEAAKVLRRRHFS
Mvan_3264|M.vanbaalenii_PYR-1 VYDGPRLVASHERAVGRYVEVLVLDHYLEVLKTKPGALPGATALAQAKAR
. : .
Mflv_2877|M.gilvum_PYR-GCK DLGADAQAFLVGAAAIG--NTRLASELEVLLALGAAHGTDALVSALHRAV
MAV_3533|M.avium_104 ALGTEAQQFLVGAAAIG--NTRLKSELDILLGLGAAHGEQALIDALRRAV
Rv3428c|M.tuberculosis_H37Rv LVGPASQQVIAEFMRDN--AIHHLRSAQGVLGLRDKHGCDRLEAACARAI
TH_4229|M.thermoresistible__bu AHGPN-IGIYAERILDDPLPWTRMRTVYRLLGLVRRYGAQRVEAACSLSL
Mb2968|M.bovis_AF2122/97 AASPVVEPQVQVRSLSD---------YDDALGVDIDGGVA----------
Mvan_3264|M.vanbaalenii_PYR-1 GVFTASHQSYWDAARSTRGDAKGTRALIAILLAHRSMPAGALIAAMDRAV
. *
Mflv_2877|M.gilvum_PYR-GCK AFRRFRAADVRSILAAGTGTPQPR------PAGDALILDLPVAPTRSLDA
MAV_3533|M.avium_104 AFRRFRAADVRSILAAGAGTPQPR------PAGDALVLDLPTVETRSLEA
Rv3428c|M.tuberculosis_H37Rv EVGDPSYRTIKGILVAGTEHAAN---------------EPTTSSPASTAG
TH_4229|M.thermoresistible__bu DLDVVSVTKIASMLERATETCAPALPRAVGQEATRFSRDPSEFSSTPTPL
Mb2968|M.bovis_AF2122/97 --------------------------------------------------
Mvan_3264|M.vanbaalenii_PYR-1 TSGCLDPETVLIDARRAMAPLAPVAAIG--------ALARYDRPPPSLAD
Mflv_2877|M.gilvum_PYR-GCK YKISVVDGEATS
MAV_3533|M.avium_104 YKINTTDGTAS-
Rv3428c|M.tuberculosis_H37Rv GVPARP------
TH_4229|M.thermoresistible__bu TVISHSESEETR
Mb2968|M.bovis_AF2122/97 ------------
Mvan_3264|M.vanbaalenii_PYR-1 YDDLLTGSDS--