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MLTVEDWAEIRRLHRAEGLPIKMIARVLGISKNTVKSALESNQQPKYERAPQGSIVDAVEPRIRELLQAY PTMPATVIAERIGWERSIRVLSARVAELRPVYLPPDPASRTTYVAGEIAQCDFWFPPIELPVGFGQTRTA KQLPVLTMVCAYSRWLLAMLLPSRCAEDLFAGWWRLIEALGAVPRVLVWDGEGAIGRWRGGRSELTTECQ AFRGTLAAKVLICRPADPEAKGLIERAHDYLERSFLPGRVFASPADFNAQLGAWLALVNTRTRRALGCAP TDRIGADRAAMLSLPPVAPATGWCTSLRLPRDHYVRCDSNDYSVHPGVIGHRVLVRADLERVHVFCDGEL VADHERIWAVHQTVSDPAHVEAAKVLRRRHFSAASPVVEPQVQVRSLSDYDDALGVDIDGGVA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2943 | - | - | 100% (413) | IS1533 transposase |
| M. tuberculosis H37Rv | Rv3637 | - | 3e-57 | 64.20% (162) | transposase |
| M. tuberculosis H37Rv | Rv3636 | - | 9e-41 | 74.55% (110) | transposase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2968 | - | 0.0 | 100.00% (413) | IS1533 transposase |
| M. gilvum PYR-GCK | Mflv_0578 | - | 1e-48 | 65.71% (140) | integrase, catalytic region |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_1373 | - | 2e-05 | 24.44% (315) | transposase for ISMyma05 |
| M. avium 104 | MAV_3533 | - | 3e-13 | 25.63% (355) | transposase |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_3774 | - | 1e-06 | 26.21% (248) | PUTATIVE transposase IstA protein, putative |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_0482 | - | 1e-169 | 69.64% (415) | integrase catalytic subunit |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2943|M.tuberculosis_H37Rv ---MLTVEDWAEIRRLHRAEGLPIKMIARVLGISKNTVKSALE-------
Mb2968|M.bovis_AF2122/97 ---MLTVEDWAEIRRLHRAEGLPIKMIARVLGISKNTVKSALE-------
Mflv_0578|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0482|M.vanbaalenii_PYR-1 ---MLSVEDWAEIRRLHRAEGLPIKMIARTLGISRNTVRAALA-------
MAV_3533|M.avium_104 ---MNIISAYHQVGSYRGAA----ELCGTTHKTVKRVIERAEA-------
MMAR_1373|M.marinum_M MLQELRMSEMRYRAVLEVLDGAPVTAVARRFGVSRQTVHAWLRRYAEEGA
TH_3774|M.thermoresistible__bu ---MLTWEDDVEVHALAKRG-WTISAIARHTGFDRKTVRKYLAGDG----
Rv2943|M.tuberculosis_H37Rv -----SNQQPKYER-APQGSIVDAVEPRIRELLQAYPTMPATVIAER-IG
Mb2968|M.bovis_AF2122/97 -----SNQQPKYER-APQGSIVDAVEPRIRELLQAYPTMPATVIAER-IG
Mflv_0578|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0482|M.vanbaalenii_PYR-1 -----SEGPPKYER-KPAGSAVDAFEDAIRVELKKTPTMPATVIAER-VG
MAV_3533|M.avium_104 -----GGAPPREPRPRNLDAFTDLVATRVEKSHGKMSAKRMLPIARA-AG
MMAR_1373|M.marinum_M ALNLEDRSSRPHRCPHQMPVEVEARVLTLRDAHPRWGPTRIVYELQR-DG
TH_3774|M.thermoresistible__bu -----TPGVRARPGPDPFDPFVDYVTARLTEDPHLWARTLFDELEDLGFG
Rv2943|M.tuberculosis_H37Rv WERSIRVLSARVAELRPVYLPPDPAS-RTTYVAGEIAQCDFWFPPIELPV
Mb2968|M.bovis_AF2122/97 WERSIRVLSARVAELRPVYLPPDPAS-RTTYVAGEIAQCDFWFPPIELPV
Mflv_0578|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0482|M.vanbaalenii_PYR-1 WTRGMTVFSERVRELRPAYLPPDPAG-RTSYDPGDIAQCDLWFPPTTIPV
MAV_3533|M.avium_104 YQGSARNFRRLVAEQKVLWRNANRHQ-RRP---------AVWSPGDYLVM
MMAR_1373|M.marinum_M VPVVPGRSSVYRALVRNGRIDPAKRR-RRRSDYKRWERGRPMELWQMDVV
TH_3774|M.thermoresistible__bu LSYQSLTRNIRTRNLRPVCEACRTATGRPNAVIPHPPGEETQWDWLELPD
Rv2943|M.tuberculosis_H37Rv GFGQTRTAKQLPVLTMVCAYSRWLLAMLLPSRCAEDLFAGWWRLIEALGA
Mb2968|M.bovis_AF2122/97 GFGQTRTAKQLPVLTMVCAYSRWLLAMLLPSRCAEDLFAGWWRLIEALGA
Mflv_0578|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0482|M.vanbaalenii_PYR-1 GYGQTRTPTQLPVLTMVLGYSRWLSAILLPSRRAEDLFAGWWQLIAALGA
MAV_3533|M.avium_104 DWAEAAPG--LMVFCAVLAYSRWRFVRFAADEKASTTLAMIAEALEAIGG
MMAR_1373|M.marinum_M GGLHLRDGIEVKVVTGIDDNSRFVVSAKVVARATARPVCAALLEALRRHG
TH_3774|M.thermoresistible__bu PPASWGWGKTAHLLVGSLSHSGKWRGNLAPSEDQPHLVAGLDRVTRGLGG
Rv2943|M.tuberculosis_H37Rv VPRVLVWDGEGAIGRWRGGRSELTT-ECQAFRGTLAAKVLICRPADPEAK
Mb2968|M.bovis_AF2122/97 VPRVLVWDGEGAIGRWRGGRSELTT-ECQAFRGTLAAKVLICRPADPEAK
Mflv_0578|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0482|M.vanbaalenii_PYR-1 VPRTLVWDGEGAIGRNRGGRIELTR-DCQAFRGVLGTKVVVLKPAEPEHK
MAV_3533|M.avium_104 VPAKILADRMGCLKGGVVANVVVPTPDYVRFASHYGFVPDFCHGADPQSK
MMAR_1373|M.marinum_M VPEQILTDNGKVFTGRFGPGGSSAEVLFDRVCVENGIGHLLTAPRSPTTT
TH_3774|M.thermoresistible__bu LTRVWRFDRMATVCD---PGSGRVTASFAGVAKHYGVSVAICPPRRGNRK
Rv2943|M.tuberculosis_H37Rv GLIERAHD-------------------------YLERSFLPGRVFASPAD
Mb2968|M.bovis_AF2122/97 GLIERAHD-------------------------YLERSFLPGRVFASPAD
Mflv_0578|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0482|M.vanbaalenii_PYR-1 GIIERAHD-------------------------YFERSFLPGREFNGPGD
MAV_3533|M.avium_104 GIVENLCG-------------------------YAQDDLAVPLLTEAALA
MMAR_1373|M.marinum_M GKVERLHKTMRA-------------------EIFAEVDGVFDAIAELQAA
TH_3774|M.thermoresistible__bu GVVEKVNHTAAQRWWRTLADDLTVEAAQASLDRFARVRGDTRLRATADGR
Rv2943|M.tuberculosis_H37Rv --------FNAQLGAWLALVNTRTRRALGCAPTDRIGADRAAMLSL---P
Mb2968|M.bovis_AF2122/97 --------FNAQLGAWLALVNTRTRRALGCAPTDRIGADRAAMLSL---P
Mflv_0578|M.gilvum_PYR-GCK --------------------------MLGCAPTDRIGADLAAMLAL---P
Mvan_0482|M.vanbaalenii_PYR-1 --------FNHQFSKWLHVVNARRRRVLGCAPTDRIGADLAAMLAL---P
MAV_3533|M.avium_104 GEQVDLRALNAQAQLWCAEVNATVHSEICAVPNDRLVDERTVLREL---P
MMAR_1373|M.marinum_M IDRWVQYYNTARPHQSLGMVAPAARFALAAGPDLSVVEPVAAVPAEGQHP
TH_3774|M.thermoresistible__bu SSVAVVAXIYVRTAEQWVGVCPGCMVRSGVCPGCMVRSARSKGWVSTRPR
* : :
Rv2943|M.tuberculosis_H37Rv PVAPATG-----WCTSLRLPRDHYVRCDSNDYSVHPGVIGHRVLVRADLE
Mb2968|M.bovis_AF2122/97 PVAPATG-----WCTSLRLPRDHYVRCDSNDYSVHPGVIGHRVLVRADLE
Mflv_0578|M.gilvum_PYR-GCK PVPPQVG-----WRNSTRLARDHYVRLDSNDYSVHPGVIGRRIEVVADLD
Mvan_0482|M.vanbaalenii_PYR-1 PVPPQVG-----WRNSTRLARDHYVRLDSNDYSVHPGVIGRRIEVVADLD
MAV_3533|M.avium_104 SLRPTIGS----GSVRRKVDGLSCIRYGSARYSVPQRLVGATVAVVVDHG
MMAR_1373|M.marinum_M GALVDLRD----AGVRRWVNRHGSISVAGFRYRVPIVLAGEPVSVVVADN
TH_3774|M.thermoresistible__bu DIKIGPDIPRIVWRKRKWVCANMCCDRKSFTESVPSIPPRARVTVRAKRE
: . * : * .
Rv2943|M.tuberculosis_H37Rv RVHVFC--DGELVADHERIWAVHQTVSDPAHVEAAKVLRR---------R
Mb2968|M.bovis_AF2122/97 RVHVFC--DGELVADHERIWAVHQTVSDPAHVEAAKVLRR---------R
Mflv_0578|M.gilvum_PYR-GCK RVQVFC--EGKTVAEHERVWAWHQTITDPEHREAANMLRR---------N
Mvan_0482|M.vanbaalenii_PYR-1 RVQVFC--EGKTVAEHERVWAWHQTITDPEHREAANMLRR---------N
MAV_3533|M.avium_104 ALILLEPATGVIVAEHELVSPGEVSILDEHYDGPRPAPSRGPRPKTQAEK
MMAR_1373|M.marinum_M LVSIYHHDVLVASHVQHRKTDNTTGVVRQGRRTARPVTSG---------I
TH_3774|M.thermoresistible__bu MASAVLDDDRSVKAVAAAYGCTWNTCHDAVIATADPVLAGEP----EAVS
.
Rv2943|M.tuberculosis_H37Rv HFSAASPVVEP-------QVQVRSLSD-----------------------
Mb2968|M.bovis_AF2122/97 HFSAASPVVEP-------QVQVRSLSD-----------------------
Mflv_0578|M.gilvum_PYR-GCK RISALRPVTDSDQQ---VLVEQRRLSD-----------------------
Mvan_0482|M.vanbaalenii_PYR-1 RISALRPVTDSDQQ---VLVEQRRLSD-----------------------
MAV_3533|M.avium_104 RFCALGTEAQQFLVGAAAIGNTRLKSE-----------------------
MMAR_1373|M.marinum_M VVTRVVDSNGDVSFAGTMYRAGRVWRG-----------------------
TH_3774|M.thermoresistible__bu VLGIDETRRGKAKWETCSQTGTRSWVDRFDTGLVDITGTGGLLVQVNGRA
. *
Rv2943|M.tuberculosis_H37Rv ---------------------YDDALGVDIDGG--VA-------------
Mb2968|M.bovis_AF2122/97 ---------------------YDDALGVDIDGG--VA-------------
Mflv_0578|M.gilvum_PYR-GCK ---------------------YDAALGIDLGEGGLVS-------------
Mvan_0482|M.vanbaalenii_PYR-1 ---------------------YDAALGIDLGEGGLVS-------------
MAV_3533|M.avium_104 ---------------------LDILLGLGAAHGEQALIDALRRAVAFRRF
MMAR_1373|M.marinum_M ---------------------KQVEVSIVAESVQIACAGAIVRTHAIRHD
TH_3774|M.thermoresistible__bu AKPVTDWLDQRDPGWKATIEFVAIDMSVTYANAARQALPHAKLIVDRFHL
:.:
Rv2943|M.tuberculosis_H37Rv --------------------------------------------------
Mb2968|M.bovis_AF2122/97 --------------------------------------------------
Mflv_0578|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0482|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_3533|M.avium_104 RAADVRSILAAGAGTPQPRPAGDALVLDLPTVETRSLEAYKINTTDGTAS
MMAR_1373|M.marinum_M RAKEHGAFATPHGRPRKPRQD----APEGPGVKATPLRGRPEGRALTPAP
TH_3774|M.thermoresistible__bu VKRANEMVDEVRRRTTQAHRLRRGRKSDPEWINRRRLLRAAERLTDEQRH
Rv2943|M.tuberculosis_H37Rv --------------------------------------------------
Mb2968|M.bovis_AF2122/97 --------------------------------------------------
Mflv_0578|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0482|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_3533|M.avium_104 --------------------------------------------------
MMAR_1373|M.marinum_M --------------------------------------------------
TH_3774|M.thermoresistible__bu KLFVKLTSADPNGDIAAAWIAKELLRDVLACTARGGLTYEIRDALYRFYT
Rv2943|M.tuberculosis_H37Rv --------------------------------------------------
Mb2968|M.bovis_AF2122/97 --------------------------------------------------
Mflv_0578|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0482|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_3533|M.avium_104 --------------------------------------------------
MMAR_1373|M.marinum_M --------------------------------------------------
TH_3774|M.thermoresistible__bu FCAACSVPEISKLARTISAWQEPMILAIQTGLSNARSEGYNRIIKHVGRI
Rv2943|M.tuberculosis_H37Rv -----------------------------------
Mb2968|M.bovis_AF2122/97 -----------------------------------
Mflv_0578|M.gilvum_PYR-GCK -----------------------------------
Mvan_0482|M.vanbaalenii_PYR-1 -----------------------------------
MAV_3533|M.avium_104 -----------------------------------
MMAR_1373|M.marinum_M -----------------------------------
TH_3774|M.thermoresistible__bu AFGFRNPENQRRRVRWACTRQSRRTPPSTKQVRPC