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DIISAYQQLGSYRAAAAECGTTHRTVKKVVKKFEADQAGVPPLPRAERAHNYDAVADLVAERVDKSKGRI SAKRLLPKARAAGYTGSDRNFRRLVAEAKALWRSENHRGRRPAVWEPGEYLVIDWAQAAPGLFLFCAVLA FSRWRFVRFATDERASTTLALIAETLSAAGGVPAKVLADRMACLKGGVVANVVVPTPDYVRLASHYGFAP DFCHASDPQSKGIVENLCGYAQDDLAVPLLTEAAVTGTPIDLRDANAAAEVWCAEVNAATHSEICAIPDE RLITERELLAPLPSLRLQIGAPSVLRKVDRLSCVRYGSARYSVPTRLIGTTVAVVVDHGALCLLEPATGV IVAEHELVAPGGVSILDEHYDGPRPAPDRGPRPKTTVEKQFCDLGADAQAFLVGAAAIGNTRLASELEVL LALGAAHGTDALVSALHRAVAFRRFRAADVRSILAAGTGTPQPRPAGDALILDLPVAPTRSLDAYKISVV DGEATS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2877 | - | - | 100% (497) | integrase catalytic subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2968 | - | 5e-09 | 24.65% (353) | IS1533 transposase |
| M. tuberculosis H37Rv | Rv2943 | - | 5e-09 | 24.65% (353) | IS1533 transposase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_3533 | - | 0.0 | 75.40% (496) | transposase |
| M. smegmatis MC2 155 | MSMEG_2151 | - | 2e-07 | 25.44% (338) | transposase IstA protein, putative |
| M. thermoresistible (build 8) | TH_4229 | - | 6e-06 | 28.00% (250) | PUTATIVE putative acyl-CoA synthase |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_3894 | - | 0.0 | 90.51% (495) | integrase catalytic subunit |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2968|M.bovis_AF2122/97 -----MLTVEDWAEIRRLHRAEGLPIK---MIARVLGISKNTVKSALESN
Rv2943|M.tuberculosis_H37Rv -----MLTVEDWAEIRRLHRAEGLPIK---MIARVLGISKNTVKSALESN
Mflv_2877|M.gilvum_PYR-GCK -----MDIISAYQQLGSYRAAAAECGT---THRTVKKVVKKFEADQAGVP
Mvan_3894|M.vanbaalenii_PYR-1 -----MDIISAYQQLGSYRAAAAECGT---THRTVKRVVDKFEADQAGVR
MAV_3533|M.avium_104 -----MNIISAYHQVGSYRGAAELCGT---THKTVKRVIERAEAGGA---
MSMEG_2151|M.smegmatis_MC2_155 -----MLTWEDDVEVHALR-KRGWTIS---AIARHTGRDRKTIADYLSGK
TH_4229|M.thermoresistible__bu MAFREVNVNEIREVLRLWLGVAGLPAPGLRTIAAHCGLDRKTVRRYVQAA
: . : .
Mb2968|M.bovis_AF2122/97 QQPKYERAP---------QGSIVDAVEPRIRELLQAYPTMPATVIAERIG
Rv2943|M.tuberculosis_H37Rv QQPKYERAP---------QGSIVDAVEPRIRELLQAYPTMPATVIAERIG
Mflv_2877|M.gilvum_PYR-GCK PLPRAERAHN--------YDAVADLVAERVDKSKGRISAKRLLPKARAAG
Mvan_3894|M.vanbaalenii_PYR-1 PPPRAERAHN--------YDTVSGLVAERVDKSKGRISAKRLLPKARAAG
MAV_3533|M.avium_104 -PPREPRPRN--------LDAFTDLVATRVEKSHGKMSAKRMLPIARAAG
MSMEG_2151|M.smegmatis_MC2_155 RTPGVRARPGP-----DPFEPFVDYVAARLTEDP-HLWARTLLDELEQLG
TH_4229|M.thermoresistible__bu HAAGLRRDDDASVIDDGLIGAVAEAVRPVRPHGHGAAWEQLLAFEGQIRA
. .. * . . .
Mb2968|M.bovis_AF2122/97 WERSIRV------------LSA--RVAELRPVYLPPDPASRTTYVAGEIA
Rv2943|M.tuberculosis_H37Rv WERSIRV------------LSA--RVAELRPVYLPPDPASRTTYVAGEIA
Mflv_2877|M.gilvum_PYR-GCK YTGSDRN------------FRR--LVAEAKALWRSENHRGRRP-------
Mvan_3894|M.vanbaalenii_PYR-1 YRGSDRN------------FRR--LVAEAKALWRSENHRGRRP-------
MAV_3533|M.avium_104 YQGSARN------------FRR--LVAEQKVLWRNANRHQRRP-------
MSMEG_2151|M.smegmatis_MC2_155 FPLSYQS------------LTRNIRARNLRPDCQACRTATERP------N
TH_4229|M.thermoresistible__bu WVAGDGEQRPLTITKIHTLLARQGCVVPYRTLHRFASERCGFGR-KGTTV
: . : . :
Mb2968|M.bovis_AF2122/97 QCDFWFPPIELPVGFGQTRTAKQ--------LPVLTMVCAYSRWLLAMLL
Rv2943|M.tuberculosis_H37Rv QCDFWFPPIELPVGFGQTRTAKQ--------LPVLTMVCAYSRWLLAMLL
Mflv_2877|M.gilvum_PYR-GCK --AVWEPGEYLVIDWAQAAPG----------LFLFCAVLAFSRWRFVRFA
Mvan_3894|M.vanbaalenii_PYR-1 --AVWEPGEYLVIDWAQAAPG----------LFLFCAVLAFSRWRFVRFA
MAV_3533|M.avium_104 --AVWSPGDYLVMDWAEAAPG----------LMVFCAVLAYSRWRFVRFA
MSMEG_2151|M.smegmatis_MC2_155 SVIEHAPGDETQWDWLELPDPPESW-GWGKTAHLLVGSLAHSGKWRAALT
TH_4229|M.thermoresistible__bu RVADGDPGVECQIDFGYLGMLTDATDGRRRKVHALIFTAVYSRHMFVWLT
* .: : ..* . :
Mb2968|M.bovis_AF2122/97 PSRCAEDLFAGWWRLIEALGAVPRVLVWDGEGAIG-RWRGGRSELTTECQ
Rv2943|M.tuberculosis_H37Rv PSRCAEDLFAGWWRLIEALGAVPRVLVWDGEGAIG-RWRGGRSELTTECQ
Mflv_2877|M.gilvum_PYR-GCK TDERASTTLALIAETLSAAGGVPAKVLADRMACLKGGVVANVVVPTPDYV
Mvan_3894|M.vanbaalenii_PYR-1 ANERASTTLALIAEALAAAGGVPAKVLADRMACLKGGVVANVVVPTPDYV
MAV_3533|M.avium_104 ADEKASTTLAMIAEALEAIGGVPAKILADRMGCLKGGVVANVVVPTPDYV
MSMEG_2151|M.smegmatis_MC2_155 PSEDQPQLVAALDRVTRELGGCTRVWRFDRMATVCDPGSGR---VTASFA
TH_4229|M.thermoresistible__bu YSQTLAAVIAGCQAAWAFFGGVFAVLIPDNLKPVIASADALNPQFTRGWL
.. .* *. * : . *
Mb2968|M.bovis_AF2122/97 AFRGTLAAKVLICRPADPEAKGLIERAHDYLERSFLP-----GRVFASPA
Rv2943|M.tuberculosis_H37Rv AFRGTLAAKVLICRPADPEAKGLIERAHDYLERSFLP-----GRVFASPA
Mflv_2877|M.gilvum_PYR-GCK RLASHYGFAPDFCHASDPQSKGIVENLCGYAQDDLAVPLLTEAAVTGTPI
Mvan_3894|M.vanbaalenii_PYR-1 RLAGHYGFAPDFCHASDPHFKGIVENLCGYAQDDLAVPLLTEAAVTATPI
MAV_3533|M.avium_104 RFASHYGFVPDFCHGADPQSKGIVENLCGYAQDDLAVPLLTEAALAGEQV
MSMEG_2151|M.smegmatis_MC2_155 GVAKHYGVSVAICPPRRGNRKGVVEKVNHTAAQRWWR-------TLDDEL
TH_4229|M.thermoresistible__bu DYAGHGGFLTDPARVRSPKDKPRVERVVQYVRRNFWDG--------ETFS
. . . * :*.
Mb2968|M.bovis_AF2122/97 DF---NAQLGAWLALVNTRTRRALGCAPTDRIGADRAAMLSLPPVAPATG
Rv2943|M.tuberculosis_H37Rv DF---NAQLGAWLALVNTRTRRALGCAPTDRIGADRAAMLSLPPVAPATG
Mflv_2877|M.gilvum_PYR-GCK DLRDANAAAEVWCAEVNAATHSEICAIPDERLITERELLAPLPSLRLQIG
Mvan_3894|M.vanbaalenii_PYR-1 TLRAANAAAVAWCAEVNTRVHSEIHAIPDERLIVERELLQPLPSLRLQIG
MAV_3533|M.avium_104 DLRALNAQAQLWCAEVNATVHSEICAVPNDRLVDERTVLRELPSLRPTIG
MSMEG_2151|M.smegmatis_MC2_155 TAEAAQASVDRFARVRGGTRMRATADGRSAVAVVAKTEPLAPVPATPYPV
TH_4229|M.thermoresistible__bu SLDEAQHVATVWCERTAGTRIHGTTCARPLEVFTAEEQPLLLAMPGVYDV
: : .
Mb2968|M.bovis_AF2122/97 WCTSLR-LPRDHYVRCDSNDYSVHPGVIGHRVLVRADLERVHVFC--DGE
Rv2943|M.tuberculosis_H37Rv WCTSLR-LPRDHYVRCDSNDYSVHPGVIGHRVLVRADLERVHVFC--DGE
Mflv_2877|M.gilvum_PYR-GCK APSVLRKVDRLSCVRYGSARYSVPTRLIGTTVAVVVDHGALCLLEPATGV
Mvan_3894|M.vanbaalenii_PYR-1 AASVLRKVDRLSCVRYGSARYSVPMRLIGTAVAVVVDHGAIVLLEPATGA
MAV_3533|M.avium_104 SGSVRRKVDGLSCIRYGSARYSVPQRLVGATVAVVVDHGALILLEPATGV
MSMEG_2151|M.smegmatis_MC2_155 IISQTRTASRQALVSYRGNRYSVPPELAAAQVVVSHPVGAQFCDIATVAG
TH_4229|M.thermoresistible__bu PVFKAVKVHRDFHAEVAKALYSLPECWIGTTLDVRADGELVKFYHRGTLV
**: . : *
Mb2968|M.bovis_AF2122/97 LVADHERIWAVHQTVSDPAH------------------------------
Rv2943|M.tuberculosis_H37Rv LVADHERIWAVHQTVSDPAH------------------------------
Mflv_2877|M.gilvum_PYR-GCK IVAEHELVAPGGVSILDEHYDGPRPAPDRGPRPKTTVEKQFCDLGADAQA
Mvan_3894|M.vanbaalenii_PYR-1 IVAEHELLAPGAVSILDEHYDGPRPAPSRGPRPKTTVEKQFCELGEDAQA
MAV_3533|M.avium_104 IVAEHELVSPGEVSILDEHYDGPRPAPSRGPRPKTQAEKRFCALGTEAQQ
MSMEG_2151|M.smegmatis_MC2_155 IVIARHRMAADGLGVMVRDS------------------------------
TH_4229|M.thermoresistible__bu KVHPRQPAGGRSTDRGDLPEHKAGYALRDLAALIAACAAHGPNIGIYAER
* :.
Mb2968|M.bovis_AF2122/97 -----------------------------------VEAAKVLRRRHFSAA
Rv2943|M.tuberculosis_H37Rv -----------------------------------VEAAKVLRRRHFSAA
Mflv_2877|M.gilvum_PYR-GCK FLVGAAAIGNTRLASELEVLLALGAAHGTDALVSALHRAVAFRRFRAADV
Mvan_3894|M.vanbaalenii_PYR-1 FLIGAAAIGNTRLGSELEVLLALGAAHGTDALTAALHRAVAFRRFRAADV
MAV_3533|M.avium_104 FLVGAAAIGNTRLKSELDILLGLGAAHGEQALIDALRRAVAFRRFRAADV
MSMEG_2151|M.smegmatis_MC2_155 ---------------------GHVIALDTMAMATASTGRPHRRKERIPPG
TH_4229|M.thermoresistible__bu ILDDPLPWTRMRTVYRLLGLVRRYGAQRVEAACSLSLDLDVVSVTKIASM
: .
Mb2968|M.bovis_AF2122/97 SPVVEPQVQVRSLSDYDDALGVDIDGGVA--------------------
Rv2943|M.tuberculosis_H37Rv SPVVEPQVQVRSLSDYDDALGVDIDGGVA--------------------
Mflv_2877|M.gilvum_PYR-GCK RSILAAGTGTPQPRPAGDALILDLPVAPTRSLDAYKIS-VVDGEATS--
Mvan_3894|M.vanbaalenii_PYR-1 RSILAVGTGAPQPRPAGDALILDLPVAPTRSLDAYKFTPAVDGEVIQ--
MAV_3533|M.avium_104 RSILAAGAGTPQPRPAGDALVLDLPTVETRSLEAYKIN-TTDGTAS---
MSMEG_2151|M.smegmatis_MC2_155 PAAKAAAAQLLHLNDANQEAAESSTWSTDSTVIDLSAYERAAQKRTIQ-
TH_4229|M.thermoresistible__bu LERATETCAPALPRAVGQEATRFSRDPSEFSSTPTPLTVISHSESEETR
.: