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M. tuberculosis H37Rv Rv3427c (-)

annotation: POSSIBLE TRANSPOSASE
coordinates: 3843885 - 3844640
length: 251

SICDPALRNALRTLKLSGMLDTLDARLAQTRNGDLGHLEFLQALREDEIARRESAALTRRLRRAKFEAQA
TFEDFDFTANPKLPGAMLRDLAALRWLDAGESVILHGPVGVGKTHVAQALVHAVARRGGDVRFAKTSRML
SDLAGGHADRSWGQRIREYTKPLVLILDDFAMREHTAMHADDLYELISDRAITGKPLILTSNRAPNNWYG
LFPNPVVAESLLDRLINTSHQILMDGPSYRPRKRPGRTTS*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3427c--100% (251)POSSIBLE TRANSPOSASE
M. tuberculosis H37RvRv3638-5e-1425.21% (238) transposase
M. tuberculosis H37RvRv2944-6e-1132.37% (139) IS1533 transposase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3662-5e-1425.21% (238) transposase
M. gilvum PYR-GCKMflv_2875-2e-1827.31% (227) IstB ATP binding domain-containing protein
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum M-----
M. avium 104MAV_3532-6e-1927.90% (233) helper protein
M. smegmatis MC2 155MSMEG_2150-7e-2529.66% (236) putative transposition helper protein
M. thermoresistible (build 8)TH_2826-3e-4439.33% (239) PUTATIVE putative ABC transporter-related protein
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_3265-3e-1928.64% (206) IstB ATP binding domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb3662|M.bovis_AF2122/97            -------------MAAKTATNSRDVAAELAYLTRALKAPTLRGAIEQLAD
Mvan_3265|M.vanbaalenii_PYR-1       ----------MTTTASATTTVDAAAQASIGAAARELHLPTVRTEATRLAE
Mflv_2875|M.gilvum_PYR-GCK          -----------------------------------MKLAAVRRTAPEVLI
MAV_3532|M.avium_104                ---------MTTAAKPVAPSSAAPLAADLDAALRRLKLATVRRNAAEVLQ
MSMEG_2150|M.smegmatis_MC2_155      MTPTPRTAKNTATVTEEPPSTAASRYQKLRSHLAELKLHAAAAALPAVLD
Rv3427c|M.tuberculosis_H37Rv        ------------MSICDP---------ALRNALRTLKLSGMLDTLDARLA
TH_2826|M.thermoresistible__bu      ------------MTTSTNRKPAEPVGADLLRLLKTLKLGALADTLPERAA
                                                                       ::             

Mb3662|M.bovis_AF2122/97            RARTKTWSYEEFLAACLQREVSARESHGGEGRIRAARFPSRKSLEEFDFD
Mvan_3265|M.vanbaalenii_PYR-1       IAGRERHTHLGYLAEVLAAEVDDRTERRRARRINDAKFPRLKRLAEFNID
Mflv_2875|M.gilvum_PYR-GCK          TAKTQRWTPEEVLRTLVETELAARDASNVVNRLKTAAFPVPKTLESFEVA
MAV_3532|M.avium_104                VAKTQRWTPEEILRTLVEAEIAARDASNTANRLKAAAFPVTKTLDGFDVT
MSMEG_2150|M.smegmatis_MC2_155      QASAENLSLTVALERLLAVEVEASTARRLAGRLRFACLPTPATLDDFDVD
Rv3427c|M.tuberculosis_H37Rv        QTRNGDLGHLEFLQALREDEIARRESAALTRRLRRAKFEAQATFEDFDFT
TH_2826|M.thermoresistible__bu      LARQHKLSHIGFLETLLADEVSRRESRSAALRAVKAGLDPTMRFDSWNAL
                                     :          *      *:          *   * :     :  ::  

Mb3662|M.bovis_AF2122/97            HARGLKRDTIAHLGTLDFVT-----------------LAIGIAIRACQAG
Mvan_3265|M.vanbaalenii_PYR-1       AVPGIAPATIGHLAAGHYMDAGEPVVLLGDSGTGKSHLLIGLGLAACEQG
Mflv_2875|M.gilvum_PYR-GCK          ASS-IQPKVFDYLSSLEWIRTQQNLAIIGPAGTGKSHTLIGLGTAAIHAG
MAV_3532|M.avium_104                GSS-ITAATFDYLSSLEWIRAQQNLAVIGPPGTGKSHLLIGCGHAAVHAG
MSMEG_2150|M.smegmatis_MC2_155      AAAGIDRKLIDELGTCRYLESATNILLVGPPGTGKTHLSVGLARAAAHAG
Rv3427c|M.tuberculosis_H37Rv        ANPKLPGAMLRDLAALRWLDAGESVILHGPVGVGKTHVAQALVHAVARRG
TH_2826|M.thermoresistible__bu      DDLRYDRTLLGDLTSLRFLDAGQSAIILGPVGVGKTHLATALGHMAIRRR
                                             :  * :  ::                     .    . .  

Mb3662|M.bovis_AF2122/97            HRVLFATASQWVDRLAAAHHSGTLQSELIRLARYPLLVVDEVGYIPFEPE
Mvan_3265|M.vanbaalenii_PYR-1       RRVRYVTTAQLVNELVEAADERVLSRVVARYGRLDLLCLDELGYVQIDPR
Mflv_2875|M.gilvum_PYR-GCK          HKVRYFTAADLVETLYRGLADNTVGKIIESLLRVDLIILDELGFAPLDDT
MAV_3532|M.avium_104                FKVRYFTAADLIEVLYRGLADNTVGKIIDTLLRADLVILDEIGFAPLDDT
MSMEG_2150|M.smegmatis_MC2_155      YRTYFTTAADLAARCHRAAIEGRWATTMRFYAGPTLLVIDELGYLPLPAE
Rv3427c|M.tuberculosis_H37Rv        GDVRFAKTSRMLSDLAGGHADRSWGQRIREYTKPLVLILDDFAMREHTAM
TH_2826|M.thermoresistible__bu      HSVMFGRADKLFTRLRAARLDNTVDAEIRRLAAVDVLIIDDFALRPLDAT
                                      . :  :         .  .      :       :: :*:..       

Mb3662|M.bovis_AF2122/97            AANLFFQLVSSRYER-ASLIVTSNKPFGRWGEVFGDDVVAAAMIDRLVHH
Mvan_3265|M.vanbaalenii_PYR-1       GAELLFQIITEREER-ASVAIATNLPFSEWGTVFPDPRLVAAIVDRVTFN
Mflv_2875|M.gilvum_PYR-GCK          GTQLLFRLVAGAYER-RSLAIGSHWPFEQWGRFLPEQTTAVSILDRLLHH
MAV_3532|M.avium_104                GTQLLFRLVAAGYER-RSLAIASHWPFEQWGRFLPEHTTAASILDRLLHH
MSMEG_2150|M.smegmatis_MC2_155      AASALFQVVSQRYLK-TSIVITTNRGVGSWGEILGDTTVAAAMLDRLLHR
Rv3427c|M.tuberculosis_H37Rv        HADDLYELISDRAITGKPLILTSNRAPNNWYGLFPNPVVAESLLDRLINT
TH_2826|M.thermoresistible__bu      ETSDFYEIVVERHRT-KTTIVTSNREPAEWLTMTADTLLAQSAIDRLTSA
                                     :. ::.::        .  : ::     *  .  :   . : :**:   

Mb3662|M.bovis_AF2122/97            AEVIALKGDSYRIKDRDLGRVPTVTADDQ------
Mvan_3265|M.vanbaalenii_PYR-1       AHIIETGTKSYRLRTSKTTTRTKRAT---------
Mflv_2875|M.gilvum_PYR-GCK          ATVVITDGDSYRMKDAKHRKEQPKPT---------
MAV_3532|M.avium_104                ASIVVTSGESYRMRHADHKKGAAKN----------
MSMEG_2150|M.smegmatis_MC2_155      SVVINLDGESYRLRDHQAAAETLRRATTGTRQALH
Rv3427c|M.tuberculosis_H37Rv        SHQILMDGPSYRPRKRPGRTTS-------------
TH_2826|M.thermoresistible__bu      AHTLVIEGPSYRQRTRPQLDPGPDDEHPQ------
                                    :  :     *** :