For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. tuberculosis H37Rv Rv2159c (-)

annotation: hypothetical protein Rv2159c
coordinates: 2420631 - 2421665
length: 344

KFVNHIEPVAPRRAGGAVAEVYAEARREFGRLPEPLAMLSPDEGLLTAGWATLRETLLVGQVPRGRKEAV
AAAVAASLRCPWCVDAHTTMLYAAGQTDTAAAILAGTAPAAGDPNAPYVAWAAGTGTPAGPPAPFGPDVA
AEYLGTAVQFHFIARLVLVLLDETFLPGGPRAQQLMRRAGGLVFARKVRAEHRPGRSTRRLEPRTLPDDL
AWATPSEPIATAFAALSHHLDTAPHLPPPTRQVVRRVVGSWHGEPMPMSSRWTNEHTAELPADLHAPTRL
ALLTGLAPHQVTDDDVAAARSLLDTDAALVGALAWAAFTAARRIGTWIGAAAEGQVSRQNPTG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2159c--100% (344)hypothetical protein Rv2159c
M. tuberculosis H37RvRv3327-1e-0734.94% (83) transposase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2183c-0.0100.00% (344) hypothetical protein Mb2183c
M. gilvum PYR-GCKMflv_4851-3e-0732.58% (89) hypothetical protein Mflv_4851
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3677-1e-0528.89% (135) transposase fusion protein
M. marinum MMMAR_1197-7e-0834.94% (83) hypothetical protein MMAR_1197
M. avium 104MAV_4302-6e-0727.56% (127) transposase
M. smegmatis MC2 155-----
M. thermoresistible (build 8)TH_2184-2e-0837.35% (83) PROBABLE TRANSPOSASE FUSION PROTEIN
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_1576-1e-0729.13% (127) hypothetical protein Mvan_1576

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4851|M.gilvum_PYR-GCK          --MTTTTRIEPVSPQRASLMTRLLWRYAKRRFGEVPEPFTIYAHHPGVML
Mvan_1576|M.vanbaalenii_PYR-1       ----MTTRLEPVPPHRASLLTRLMWRYAKRRFGEVPEPFAVYAHHPGLML
TH_2184|M.thermoresistible__bu      MSENQKTRIEPLSPERAPWWVRLMYRYARRRFGEVPEPFTVAAHHPGLLL
MMAR_1197|M.marinum_M               --MTQKTRIEPLPPKRAGLLVGALYRIAKRRLGEVPEPFSVVAHHRRLLV
MAV_4302|M.avium_104                --MTQKTRIEPLPPQRAGLLTRAMYRIAKRRYGQVPEPFTVAAHHRKLMV
MAB_3677|M.abscessus_ATCC_1997      --MTTTSRIAPIAPPNASLLTRFMYRVTKRRYGQVPEPFTVIAHHRKLMV
Rv2159c|M.tuberculosis_H37Rv        --MKFVNHIEPVAPRRAGGAVAEVYAEARREFGRLPEPLAMLSPDEGLLT
Mb2183c|M.bovis_AF2122/97           --MKFVNHIEPVAPRRAGGAVAEVYAEARREFGRLPEPLAMLSPDEGLLT
                                          .:: *:.* .*   .  ::  ::*. *.:***::: : .  :: 

Mflv_4851|M.gilvum_PYR-GCK          AGAMHEGMLERASTALPANVRELAVYWVARQIGCSWCVDFGAMLMRLDGL
Mvan_1576|M.vanbaalenii_PYR-1       TGAVHEGLLERTSSKVPASVRELAVYWTARQIGCSWCVDFGSMLMRLDGL
TH_2184|M.thermoresistible__bu      SSAVHETLLEKTSSRLPANVRELAVYWTARKIGCSWCVDFGAMLARLDGL
MMAR_1197|M.marinum_M               ANAVHETMVERASRTLPAGVRELAVFWTARQIGCSWCVDFGSMLQRLDGL
MAV_4302|M.avium_104                ASAVHETLVDRASKTLPASVRELAVYWTARQIGCSWCVDFGSMLQRLDGL
MAB_3677|M.abscessus_ATCC_1997      AAAVHEQMLGSASQVLPTSVRELAVFWTARTVGCSWCVDFGSMLQRLDGL
Rv2159c|M.tuberculosis_H37Rv        AGWATLRETLLVG-QVPRGRKEAVAAAVAASLRCPWCVDAHTTMLYAAGQ
Mb2183c|M.bovis_AF2122/97           AGWATLRETLLVG-QVPRGRKEAVAAAVAASLRCPWCVDAHTTMLYAAGQ
                                    :          ..  :* . :* ..  .*  : *.****  : :    * 

Mflv_4851|M.gilvum_PYR-GCK          DLARLTHIDDYATSTSFTDDERAAIDYAAAMTTDP---------------
Mvan_1576|M.vanbaalenii_PYR-1       DIARLKEIDDFATSPRFTDDERAAIAYAAAMTTDP---------------
TH_2184|M.thermoresistible__bu      NIEKLSRIDDYATSDLFDDDERAAIAYADAMTTDP---------------
MMAR_1197|M.marinum_M               DVHRLEDIDEYATSPLFSDDERAAIAYAEAITTDP---------------
MAV_4302|M.avium_104                DIQRLTEIDDYATSPAFTDDERAAIAYAVAITTDP---------------
MAB_3677|M.abscessus_ATCC_1997      DVDRLKAIDDYATSPLYTEDERVAIAYADAMTGNP---------------
Rv2159c|M.tuberculosis_H37Rv        TDTAAAILAGTAPAAGDPNAPYVAWAAGTGTPAGPPAPFGPDVAAEYLGT
Mb2183c|M.bovis_AF2122/97           TDTAAAILAGTAPAAGDPNAPYVAWAAGTGTPAGPPAPFGPDVAAEYLGT
                                           :   *.:    :   .*   . . . .*               

Mflv_4851|M.gilvum_PYR-GCK          ----HTVSDEQVADLRRRFGDKG--LMELTYQVG--VENMRARMNAALGI
Mvan_1576|M.vanbaalenii_PYR-1       ----HTVTDEQVADLRRRFGADG--VIELTYQIG--VENMRARMNAALGI
TH_2184|M.thermoresistible__bu      ----HTVTDEQVADLRRRFGDAG--VIELTTQIG--VENMRARINTALGI
MMAR_1197|M.marinum_M               ----HTVTDKQVAELRSRFGDAG--VVELTYQIG--LENMRARMNAALGI
MAV_4302|M.avium_104                ----HTVTDEQVDDLRARFGDAG--TFELTYQIG--LENMRARVNAALGI
MAB_3677|M.abscessus_ATCC_1997      ----HDITDEQVEDLRRRFGDAG--VIELTYQIG--VENMRARTYAALGI
Rv2159c|M.tuberculosis_H37Rv        AVQFHFIARLVLVLLDETFLPGGPRAQQLMRRAGGLVFARKVRAEHRPGR
Mb2183c|M.bovis_AF2122/97           AVQFHFIARLVLVLLDETFLPGGPRAQQLMRRAGGLVFARKVRAEHRPGR
                                        * ::   :  *   *   *    :*  : *  :   :.*     * 

Mflv_4851|M.gilvum_PYR-GCK          TEQGFSSGDACR-VPWTQ--------------------------------
Mvan_1576|M.vanbaalenii_PYR-1       TEQGFSSGDACR-VPWASAAQAGQGATAAEKR------------------
TH_2184|M.thermoresistible__bu      TEQGFSSGDACR-IPWAARSDQPAGGPAGSR-------------------
MMAR_1197|M.marinum_M               TEQGFNSGDACR-VPWAT-----VEPQFGR--------------------
MAV_4302|M.avium_104                TEQGFNSGDACR-IPWATGDTETSDPAANR--------------------
MAB_3677|M.abscessus_ATCC_1997      TEQGFNSGDACR-VPWAAS----PDPMGT---------------------
Rv2159c|M.tuberculosis_H37Rv        STRRLEPRTLPDDLAWATPSEPIATAFAALSHHLDTAPHLPPPTRQVVRR
Mb2183c|M.bovis_AF2122/97           STRRLEPRTLPDDLAWATPSEPIATAFAALSHHLDTAPHLPPPTRQVVRR
                                    : : :..      :.*:                                 

Mflv_4851|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1576|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2184|M.thermoresistible__bu      --------------------------------------------------
MMAR_1197|M.marinum_M               --------------------------------------------------
MAV_4302|M.avium_104                --------------------------------------------------
MAB_3677|M.abscessus_ATCC_1997      --------------------------------------------------
Rv2159c|M.tuberculosis_H37Rv        VVGSWHGEPMPMSSRWTNEHTAELPADLHAPTRLALLTGLAPHQVTDDDV
Mb2183c|M.bovis_AF2122/97           VVGSWHGEPMPMSSRWTNEHTAELPADLHAPTRLALLTGLAPHQVTDDDV
                                                                                      

Mflv_4851|M.gilvum_PYR-GCK          -----------------------------------------------
Mvan_1576|M.vanbaalenii_PYR-1       -----------------------------------------------
TH_2184|M.thermoresistible__bu      -----------------------------------------------
MMAR_1197|M.marinum_M               -----------------------------------------------
MAV_4302|M.avium_104                -----------------------------------------------
MAB_3677|M.abscessus_ATCC_1997      -----------------------------------------------
Rv2159c|M.tuberculosis_H37Rv        AAARSLLDTDAALVGALAWAAFTAARRIGTWIGAAAEGQVSRQNPTG
Mb2183c|M.bovis_AF2122/97           AAARSLLDTDAALVGALAWAAFTAARRIGTWIGAAAEGQVSRQNPTG