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M. tuberculosis H37Rv Rv3317 (sdhD)

annotation: PROBABLE SUCCINATE DEHYDROGENASE (HYDROPHOBIC MEMBRANE ANCHOR SUBUNIT) SDHD (SUCCINIC DEHYDROGENASE) (FUMARATE REDUCTASE) (FUMARATE DEHYDROGENASE) (FUMARIC HYDROGENASE)
coordinates: 3704437 - 3704871
length: 144

MSAPVRQRSHDRPASLDNPRSPRRRAGMPNFEKFAWLFMRFSGVVLVFLAIGHVFIMLMWDNGVYRLDFN
FVAQRWASPFWQTWDLLLLWLAQLHGGNGLRTIIDDYSRKDTTRFWLNSLLVLSMLFTLMLGTYVIVTFD
PNIS

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. tuberculosis H37Rv Rv3317 sdhD - 100% (144) PROBABLE SUCCINATE DEHYDROGENASE (HYDROPHOBIC MEMBRANE ANCHOR SUBUNIT) SDHD (SUCCINIC DEHYDROGENASE) (FUMARATE REDUCTASE) (FUMARATE DEHYDROGENASE) (FUMARIC HYDROGENASE)

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3346 sdhD 1e-83 99.31% (144) succinate dehydrogenase hydrophobic membrane anchor subunit
M. gilvum PYR-GCK Mflv_4845 - 7e-70 80.28% (142) putative succinate dehydrogenase
M. leprae Br4923 MLBr_00698 sdhD 2e-72 85.21% (142) putative succinate dehydrogenase hydrophobic membrane anchor
M. abscessus ATCC 19977 MAB_3674 - 2e-70 80.14% (141) succinate dehydrogenase, hydrophobic membrane anchor protein
M. marinum M MMAR_1202 sdhD 9e-74 86.62% (142) succinate dehydrogenase (hydrophobic membrane anchor
M. avium 104 MAV_4298 - 5e-73 86.62% (142) succinate dehydrogenase hydrophobic membrane anchor protein
M. smegmatis MC2 155 MSMEG_1671 - 1e-62 71.13% (142) succinate dehydrogenase hydrophobic membrane anchor protein
M. thermoresistible (build 8) TH_2181 sdhD 3e-69 80.00% (140) PROBABLE SUCCINATE DEHYDROGENASE (HYDROPHOBIC MEMBRANE
M. ulcerans Agy99 MUL_1368 sdhD 6e-72 85.71% (140) succinate dehydrogenase (hydrophobic membrane anchor
M. vanbaalenii PYR-1 Mvan_1588 - 7e-71 81.69% (142) putative succinate dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


Rv3317|M.tuberculosis_H37Rv         MS-----------------------APVRQRSHDRPASLDNPRSPRRRAG
Mb3346|M.bovis_AF2122/97            MS-----------------------APVRQRSHDRPASLDNPRSPRRRAG
MLBr_00698|M.leprae_Br4923          MSNSDL----QLRPQVQPTCQKGQLAPVRQRSYDRPASLDNPRSPRRRAG
MAV_4298|M.avium_104                MSTPDL----QLGP--------GQIAPVKQRFYDRPASLDNPRSPRRRAG
MMAR_1202|M.marinum_M               MSAPDH----QLGR--------GEHAPVLQRSHDRPASLDNPRSPRRRAG
MUL_1368|M.ulcerans_Agy99           ---------------------------MLQRSHDRPASLDNPRSPRRRAS
Mflv_4845|M.gilvum_PYR-GCK          MTQASRPASGRAENAYDHISDRGGPAPVMQRSFDRPAGLDNPRAPRRSGG
Mvan_1588|M.vanbaalenii_PYR-1       MSSGKK----MAENPYDHISDRGGPAPVMQRSYDRPAGLDNPRSPRRAGG
TH_2181|M.thermoresistible__bu      ---------------------------VLETSHDRPAALDNPRAPRRRGG
MSMEG_1671|M.smegmatis_MC2_155      MS---------APGAGE--SRLGRPAPVMEREHDRPAALDHPRAPRKPRG
MAB_3674|M.abscessus_ATCC_1997      MTTP-------QTGSHTSVRASGRPAPVLERNYDRPAALDNPRAPRRGSG
                                                               : :  .****.**:**:**:  .

Rv3317|M.tuberculosis_H37Rv         MPNFEKFAWLFMRFSGVVLVFLAIGHVFIMLMWDNGVYRLDFNFVAQRWA
Mb3346|M.bovis_AF2122/97            MPNFEKFAWLFMRFSGVVLVFLAIGHLFIMLMWDNGVYRLDFNFVAQRWA
MLBr_00698|M.leprae_Br4923          IPNFEKFAWLFMRFSGVALVVLAFGHLFIMLMWDNGVYRIDFNFVAQRWS
MAV_4298|M.avium_104                IPNFEKFAWLFMRFSGVALFVLAIGHLFIMLMWDDGVYRIDFNYVAQRWA
MMAR_1202|M.marinum_M               MPNFEKYAWLFMRFSGVVLVFLALGHLFIGLMWENGVYRIDFNYVAQRWS
MUL_1368|M.ulcerans_Agy99           MPNFEKYAWLFMRFSGVVLVFLALGHLFIGLMWENGVYRIDFNYVAQRWS
Mflv_4845|M.gilvum_PYR-GCK          MPNFEKYTWLFMRFSGIVLVFLALGHLFIMLMWENGVYRIDFNYVAQRWS
Mvan_1588|M.vanbaalenii_PYR-1       MPNFEKYAWLFMRFSGIVLVFLALGHLFIMLMWENGVYRIDFNYVAERWS
TH_2181|M.thermoresistible__bu      MPNFEKYAWLFMRFSGIVLVFLALGHLFIMLMWENGVYRIDFNYVAERWQ
MSMEG_1671|M.smegmatis_MC2_155      IPYFEKYAWLFMRFSGIALVFLALGHLFIMLMWQDGVYRIDFNYVAERWA
MAB_3674|M.abscessus_ATCC_1997      MPNFEKYAWIFMRLSGVVLIFLALGHLFIMLMWDNGVYRLDFNFVAQRWA
                                    :* ***::*:***:**:.*..**:**:** ***::****:***:**:** 

Rv3317|M.tuberculosis_H37Rv         SPFWQTWDLLLLWLAQLHGGNGLRTIIDDYSRKDTTRFWLNSLLVLSMLF
Mb3346|M.bovis_AF2122/97            SPFWQTWDLLLLWLAQLHGGNGLRTIIDDYSRKDTTRFWLNSLLVLSMLF
MLBr_00698|M.leprae_Br4923          SPFWRFWDLALLWLAQVHGGNGLRNIIDDYSRKDHTRFWLNSLLLLSMGF
MAV_4298|M.avium_104                SPFWQFWDLALLWLAQLHGGNGLRTIIDDYSRKDSTRFWLNSLLLLSMGF
MMAR_1202|M.marinum_M               SPFWQTWDLLLLWLAQLHGGNGLRVIIDDYSRKDSTRFWLNSLLVVSIVF
MUL_1368|M.ulcerans_Agy99           SPFWQTWDLLLLWLAQLHGGNGLRVIIDDYSRKDSTRFWLNSLLVVSIVF
Mflv_4845|M.gilvum_PYR-GCK          SPFWQTWDLLLLWLAQLHGGNGMRTIIADYTRKDSTKFWLNTLLALSMAF
Mvan_1588|M.vanbaalenii_PYR-1       SPFWQTWDLLLLWLAQLHGGNGMRTIIADYSRKDSTKFWLNTLLALSMAF
TH_2181|M.thermoresistible__bu      SPFWQIWDLLLLWLAQLHGGNGMRTIIADYARKDSTRFWLNALLALSIVF
MSMEG_1671|M.smegmatis_MC2_155      SPFWQIWDMALLWLAMIHGANGMRTIIGDYARKNVTKFWLNSLLLLATGF
MAB_3674|M.abscessus_ATCC_1997      SPFWQTWDLLMLWLAQLHGGNGMRTIIADYTRKDSTRFWLNCLLALSIIF
                                    ****: **: :**** :**.**:* ** **:**: *:**** ** ::  *

Rv3317|M.tuberculosis_H37Rv         TLMLGTYVIVTFDPNIS-
Mb3346|M.bovis_AF2122/97            TLMLGTYVIVTFDPNIS-
MLBr_00698|M.leprae_Br4923          TLVLGSYVLLSFDPNIS-
MAV_4298|M.avium_104                TLVLGTYVLLTFDPNISG
MMAR_1202|M.marinum_M               TLALGSYVLLTFDANIS-
MUL_1368|M.ulcerans_Agy99           TLALGSYVLLTFDANIS-
Mflv_4845|M.gilvum_PYR-GCK          TLVLGTYVLLTFDASIS-
Mvan_1588|M.vanbaalenii_PYR-1       TLVLGTYVLLTFDATIS-
TH_2181|M.thermoresistible__bu      TLVLGTYVLLTFDANIS-
MSMEG_1671|M.smegmatis_MC2_155      TLVLGSYVLVTFDANIS-
MAB_3674|M.abscessus_ATCC_1997      TVVLGTYVLLTFNPNIG-
                                    *: **:**:::*:..*.

species	id	gene	e-value	identity (len)	annotation
M. tuberculosis H37Rv	Rv3317	sdhD	-	100% (144)	PROBABLE SUCCINATE DEHYDROGENASE (HYDROPHOBIC MEMBRANE ANCHOR SUBUNIT) SDHD (SUCCINIC DEHYDROGENASE) (FUMARATE REDUCTASE) (FUMARATE DEHYDROGENASE) (FUMARIC HYDROGENASE)