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IAGALGNWLMSRGEAVAPTATVRAMAPLSVYADDQLDSTGPGQAISQVTPFLVDLPVGEGNAVVRLSQIA HATESNPTAASLVDARTIVTLSGLAPATLHAMGVRVATSFSARLFNLLITNAPGTQSQMYIAGTKLLETY SVPPLLHNQALAISVTSYNGMLYFGINADRDAMSDVDLLPGLLSQALDELLEASR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3233c | - | - | 100% (196) | hypothetical protein Rv3233c |
| M. tuberculosis H37Rv | Rv3480c | - | 2e-14 | 27.50% (200) | hypothetical protein Rv3480c |
| M. tuberculosis H37Rv | Rv1760 | - | 2e-13 | 29.59% (196) | hypothetical protein Rv1760 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3262c | - | 1e-106 | 100.00% (196) | hypothetical protein Mb3262c |
| M. gilvum PYR-GCK | Mflv_4703 | - | 2e-89 | 82.65% (196) | hypothetical protein Mflv_4703 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3551c | - | 2e-67 | 63.08% (195) | hypothetical protein MAB_3551c |
| M. marinum M | MMAR_1311 | - | 1e-92 | 85.93% (199) | hypothetical protein MMAR_1311 |
| M. avium 104 | MAV_4196 | - | 2e-91 | 85.93% (199) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. smegmatis MC2 155 | MSMEG_1882 | - | 7e-85 | 78.06% (196) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. thermoresistible (build 8) | TH_2686 | - | 3e-85 | 78.06% (196) | PUTATIVE Diacylglycerol O-acyltransferase |
| M. ulcerans Agy99 | MUL_1313 | - | 5e-15 | 28.57% (196) | hypothetical protein MUL_1313 |
| M. vanbaalenii PYR-1 | Mvan_1764 | - | 1e-88 | 81.12% (196) | hypothetical protein Mvan_1764 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4703|M.gilvum_PYR-GCK -------MVTRLSASDASFYRLENSSTPMYVGSLQILRRPRSG---LSYE
Mvan_1764|M.vanbaalenii_PYR-1 -------MVTRLSASDASFYRLESSSTPMYVGSLQILRKPRNG---LSYE
MSMEG_1882|M.smegmatis_MC2_155 -------MVTRLSASDAAFYRLENTSTPMYVGSLSILRKPRAG---LSYE
Rv3233c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3262c|M.bovis_AF2122/97 -------MVTRLSASDASFYQLENTATPMYVGLLLILRRPRAG---LSYE
MMAR_1311|M.marinum_M -------MVTRLSNTDASFYRLENTATPMYVGSLMILRRPRAG---LSYE
MAV_4196|M.avium_104 -------MVSRLSPADASFYRLENTATPMYVGSLAILRRPRAG---LSYE
TH_2686|M.thermoresistible__bu -------MVTRLSASDADFFHLEDTSTPMYVGSLAILRRPRGG---LSYE
MAB_3551c|M.abscessus_ATCC_199 MGKAARIVVSRLSALDASFYSSEDSATPMHVGSLAIIRRPRGG---FTYE
MUL_1313|M.ulcerans_Agy99 --------MRRLSSVDAQFFAMEDGRNHSHVCQLTIVEATTTDGLRLDGQ
Mflv_4703|M.gilvum_PYR-GCK TLLATVEQRLPQIPRYRQKVREVTLGLARPVWVDDRDFDITYHIRRSALP
Mvan_1764|M.vanbaalenii_PYR-1 TLLATVEQRLPLIPRYRQKVREVSFGLARPVWVDDREFDITYHVRRSALP
MSMEG_1882|M.smegmatis_MC2_155 TLLETVEKRLPQIPRYRQKVREVTLGLARPVWIDDREFDITYHIRRSALP
Rv3233c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3262c|M.bovis_AF2122/97 ALLETVEQRLPQIPRYRQKVQEVKLGLARPVWIDDRDFDITYHVRRSALP
MMAR_1311|M.marinum_M ALLATVEQRLAQIPRYRQKVREVRIGMARPVWIDDPDFDITYHVRRSALP
MAV_4196|M.avium_104 TLLHTIEQRLPQIPRYRQKVREVPVGTARPVWIDDGDFDITYHVRRSALP
TH_2686|M.thermoresistible__bu TLLATVEQRLPQIPRYRQKVRKAPIGLARPVWVDDPDFDITYHVRRSALP
MAB_3551c|M.abscessus_ATCC_199 ELLALVESRLPQVPRYRQKVKEIGFGLARPVWLDDVDFDITYHIRRSALP
MUL_1313|M.ulcerans_Agy99 RIRGLLAQRIDLMPPLRWRVREVPFGIDYPVLVQDDTFDLDSHLWESALP
Mflv_4703|M.gilvum_PYR-GCK SPGSDTQLHDLVARLGSRPLDKTRPLWEMYLAEGLAKNRVAIYTKSHQAL
Mvan_1764|M.vanbaalenii_PYR-1 SPGSDAQLHDLVARLGSRPLDKSRPLWEMYLVEGLAKNRIAIYTKSHQAL
MSMEG_1882|M.smegmatis_MC2_155 SPGSDAQLHDLVARLGSRPLDKTRPLWEMYLVEGLAGNRIAVYTKSHQAL
Rv3233c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3262c|M.bovis_AF2122/97 SPGSDEQLHELIARLAARPLDKSRPLWEMYLVEGLEKNRIALYTKSHQAL
MMAR_1311|M.marinum_M SPGSDEQLHELIARLAARPLDKSRPLWEMYLIEGLEKGRVALYTKTHQAL
MAV_4196|M.avium_104 SPGSDEQLHELIARLAARPLDKTRPLWEMYLVEGLSKNRLALYTKSHQAL
TH_2686|M.thermoresistible__bu SPGSDAQLHELIARLASRPLDKTRPLWEMYLIEGLAKNRLALYTKSHQAL
MAB_3551c|M.abscessus_ATCC_199 SPGSDGQLQDLVARLTSRPLDRSRPLWEMYLVEGLSKNRLAIYTKTHQAL
MUL_1313|M.ulcerans_Agy99 APGDDEQLGRAVADIASRPLDRARPLWELHVIHGLAGDRVALVTKLHHSV
Mflv_4703|M.gilvum_PYR-GCK VNGMAALEIGHVIADRTQKPPEFGEDIWIPG-----REPSDRQLLLGAVG
Mvan_1764|M.vanbaalenii_PYR-1 VNGMTALEIGHVIADRTQKPPAFGEDIWIPG-----REPSDRQLLFGAFG
MSMEG_1882|M.smegmatis_MC2_155 VNGMSALEVGHVIADRTQKPPEFGEDIWIPS-----REPTDRQLVLGAIG
Rv3233c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3262c|M.bovis_AF2122/97 INGVTALAIGHVIADRTRRPPAFPEDIWVPE-----RDPGTTRLLLRAVG
MMAR_1311|M.marinum_M INGVTALSLGHVIADRTQRPPPFPEDIWIPE-----RDPGNTRLVMGAIG
MAV_4196|M.avium_104 INGMTALEINHVIADRTKRPPAFPEDIWVPE-----RDPGNTRLVLGAIG
TH_2686|M.thermoresistible__bu VNGMTAPEIGHVIADRTQKPPQFGEDIWMPG-----REPGTAQLLIGAIG
MAB_3551c|M.abscessus_ATCC_199 VDGNSALSLGQVIFDRTARTPDFGEDIWVPE-----HEPSTSELVAGAVS
MUL_1313|M.ulcerans_Agy99 IDGVSGMELLGALLDTVSFPDAGPELEKPPTGTAIGNASSDAGLLARALA
Mflv_4703|M.gilvum_PYR-GCK EWITRPTQQAAAVRSAVTETVSS--------TAQIVDLGRRVADVAR---
Mvan_1764|M.vanbaalenii_PYR-1 EWITRPTAQAAALRSAVTDAVTT--------TGQLVELGRRATEVAR---
MSMEG_1882|M.smegmatis_MC2_155 EWIARPTSQVAALRDTVTEVATN--------AGELAAVGRRIADTVR---
Rv3233c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3262c|M.bovis_AF2122/97 DWLVRPGAQLQAVGSAVAGLVTN--------SGQLVETGRKVLDIAR---
MMAR_1311|M.marinum_M DWVVGPGAQLQAVGSAIAGLATN--------QSQLVNAGRRILDVAR---
MAV_4196|M.avium_104 EWLVGPSAQLQAVGSAIGGLVTN--------YGELVDAGRRVFDFVR---
TH_2686|M.thermoresistible__bu DWLTRPGAQMIAVRDNVLGMATN--------AGELVDAGRRALSVAR---
MAB_3551c|M.abscessus_ATCC_199 EWLARPGARLEAVRNTVADVASL--------TGEIGELGERMVKVVR---
MUL_1313|M.ulcerans_Agy99 SLPVQPARMVRGLPPMLRHIDQLPTMRHLPGAAVIAKVADRAERLATRNK
Mflv_4703|M.gilvum_PYR-GCK -----TVARGTAPSSPLNTTVSRNRRFSVASGSLDEFRVVRARYD-CDVN
Mvan_1764|M.vanbaalenii_PYR-1 -----TVARGAAPSSPLNTTVSRNRRFSVASGSLDEFRAVRARYD-CDVN
MSMEG_1882|M.smegmatis_MC2_155 -----TVARGTAPSSPLNTTVSRNRRFTVADHKLDDYRQVRVRYD-CDIN
Rv3233c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3262c|M.bovis_AF2122/97 -----TVARGTAPSSPLNATVSRNRRFTVARASLDDYRTVRARYD-CDVH
MMAR_1311|M.marinum_M -----NVARGTAPSSPLNAPVSRNRRLTVASGRLEDYRTVRARYD-CDVH
MAV_4196|M.avium_104 -----NVARGTAPSSPLNATVSRHRRFTVASGSLEDYRTVRARYD-CDVN
TH_2686|M.thermoresistible__bu -----TVARGTAPSSPLNTRVSRNRRFTVARHRLDDYRKVRARYD-CDVN
MAB_3551c|M.abscessus_ATCC_199 -----TAARGAAPRGPLNQRVSRSRRFGVVSTKLADYRRVRAKYD-CDVN
MUL_1313|M.ulcerans_Agy99 DGRNLQHPRAAAPKVSFGGRISAQRRFAFGSLPLDQIKAAKFAVPGATVN
Mflv_4703|M.gilvum_PYR-GCK DVVLAMVAGALRNWLLSRGEPVRATTTVRAMAPMSVYPDAEIDSTGPGQA
Mvan_1764|M.vanbaalenii_PYR-1 DVVLAVVAGALRNWLLSRGEPVRATTTVRAMAPMSVYPDTEIDSSSPGQA
MSMEG_1882|M.smegmatis_MC2_155 DVVLAVISGALRNWLLSRGEPVTPSTTVRAMAPLSVYPDEELDSPGPGQA
Rv3233c|M.tuberculosis_H37Rv -----MIAGALGNWLMSRGEAVAPTATVRAMAPLSVYADDQLDSTGPGQA
Mb3262c|M.bovis_AF2122/97 DVVLTVIAGALGNWLMSRGEAVAPTATVRAMAPLSVYADDQLDSTGPGQA
MMAR_1311|M.marinum_M DVVLAVIAGALGNWLMSRGETVSQTATVRAMAPLSVYVEDQLDSSGPGQQ
MAV_4196|M.avium_104 DVVLAVIAGALGSWLMSRGVAVSPTATVRAMAPLSVYADGDLDVSGPGQA
TH_2686|M.thermoresistible__bu DVVLAVIAGALRNWLLSRGEQVSSTATVRAMAPLSVQSDAELDSTAPGQA
MAB_3551c|M.abscessus_ATCC_199 DVVLATIAGALRNWLMSRGEPVTTASTIRAMVPMSVYRDGDLDVGGEGAA
MUL_1313|M.ulcerans_Agy99 DVVVAVCAGALRRRMIARGD--DVATPLVAMVPVSVR-------TGERQY
:*** :::** ::.: **.*:** .
Mflv_4703|M.gilvum_PYR-GCK ISEVAPFLVDLPVGESNPVVRLSQISHATESHPTAPSLVDARTIVTLSGF
Mvan_1764|M.vanbaalenii_PYR-1 ISEVVPFLVDLPVGEANPVVRLSQISHATETHPTAPSLVDARTIITLSGF
MSMEG_1882|M.smegmatis_MC2_155 ISEVSPFLVDLPVGEGNAVVRLSHITHANESNSWAVSLVDARTIVTLSGF
Rv3233c|M.tuberculosis_H37Rv ISQVTPFLVDLPVGEGNAVVRLSQIAHATESNPTAASLVDARTIVTLSGL
Mb3262c|M.bovis_AF2122/97 ISQVTPFLVDLPVGEGNAVVRLSQIAHATESNPTAASLVDARTIVTLSGL
MMAR_1311|M.marinum_M ISQVTPFLIDLPVGERNAVVRLSQVAHATESNPTAASLVDARTIVTLSGF
MAV_4196|M.avium_104 ISQVMPFLVDLPVGEPNAVVRLSQIAHATESNPTAAHLVDARTIVTLSGF
TH_2686|M.thermoresistible__bu VSDVVPFLIDLPVGERNPVVRLSQISHATETHPTASSLVDARTIVTLTGF
MAB_3551c|M.abscessus_ATCC_199 TTEVSPFLVDLPVGEGNTVVRLSQIAHATESHSAAFSLVDVPNMAALSGF
MUL_1313|M.ulcerans_Agy99 GNQISSMIVPIPTDQADARARLISAHQVMRAAKERHRAIPAKLLTEANHT
.:: .::: :*..: :. .** :. .: : . : .
Mflv_4703|M.gilvum_PYR-GCK APPTLHAMGIRVAT-----SFSARQFNLLITNVPGAQSQMYIAGTKLLET
Mvan_1764|M.vanbaalenii_PYR-1 APPTLHAMGIRVAT-----SFSARLFNLLITNAPGAQNQMYIAGTKLLET
MSMEG_1882|M.smegmatis_MC2_155 APPTLHAMGIRVAT-----GFSARLFNLLITNVPGPQKQMYVAGTKLLET
Rv3233c|M.tuberculosis_H37Rv APATLHAMGVRVAT-----SFSARLFNLLITNAPGTQSQMYIAGTKLLET
Mb3262c|M.bovis_AF2122/97 APATLHAMGVRVAT-----SFSARLFNLLITNAPGTQSQMYIAGTKLLET
MMAR_1311|M.marinum_M APPTLHAMGIRVATSFP--SFSKRTFNLLITNAPGAQSQMYVAGAKLLEA
MAV_4196|M.avium_104 APPTLHAMGIRVATSFP--SFSKRTFNLLITNAPGAQSQMYVAGTKLLET
TH_2686|M.thermoresistible__bu APATLHAMGVRVAT-----NFSARQFNLLITNVPGAQKQMYIAGTKMLES
MAB_3551c|M.abscessus_ATCC_199 VPPTLHALAARVAS-----TLPNRLFNLLVTNVPGPQAPMYLGGARLAEI
MUL_1313|M.ulcerans_Agy99 VPPALLTRAARVISMTTGSGWIRPPFNVTISNIPGSPDPLYCAGARVVSQ
.*.:* : . ** : **: ::* **. :* .*::: .
Mflv_4703|M.gilvum_PYR-GCK YSVPPLLHNQTLAIGVTSYNGMLYFGINADRDAMSDVDMLPSLLREALDE
Mvan_1764|M.vanbaalenii_PYR-1 YAVPPLLHNQALAIGVTSYNGMLYFGINADRDAMSDVDMLPSLLRESLDE
MSMEG_1882|M.smegmatis_MC2_155 YAVPPLLHNQVLAIGVTSYNGRLYFGINADRDAMSDVDVFRSLLDESLEE
Rv3233c|M.tuberculosis_H37Rv YSVPPLLHNQALAISVTSYNGMLYFGINADRDAMSDVDLLPGLLSQALDE
Mb3262c|M.bovis_AF2122/97 YSVPPLLHNQALAISVTSYNGMLYFGINADRDAMSDVDLLPGLLSQALDE
MMAR_1311|M.marinum_M YAVPPLLHNQALAISVTSYNGMLYFGINADRDAMSDVELLPALLAQSLEE
MAV_4196|M.avium_104 YSVPPLLHNQALAIGVTSYNGMLYYGINADREAMSDVDLLPALLNQALEE
TH_2686|M.thermoresistible__bu YSVPPLLRNQVLAVAVTSYHGMLYYGVNADRDAMSDVEVLPSLLSESLDE
MAB_3551c|M.abscessus_ATCC_199 YPVPPLLRNQVLSIGLTSYNGTVYYGINADREAMPDADMLPLLITEALDE
MUL_1313|M.ulcerans_Agy99 HPVNVLLDGMGLSITLLSYQDRLDFGLTADRELLPDVWHLADELAAELSA
:.* ** . *:: : **:. : :*:.***: :.*. : : *.
Mflv_4703|M.gilvum_PYR-GCK LVEAAR---------------------------
Mvan_1764|M.vanbaalenii_PYR-1 LVEAAR---------------------------
MSMEG_1882|M.smegmatis_MC2_155 LIDAAK---------------------------
Rv3233c|M.tuberculosis_H37Rv LLEASR---------------------------
Mb3262c|M.bovis_AF2122/97 LLEASR---------------------------
MMAR_1311|M.marinum_M LLEASR---------------------------
MAV_4196|M.avium_104 LVEAARS--------------------------
TH_2686|M.thermoresistible__bu LLEAAQ---------------------------
MAB_3551c|M.abscessus_ATCC_199 LLEAAQ---------------------------
MUL_1313|M.ulcerans_Agy99 LAAEVGAPRNPVADGAPTSTTGRPTAKPGAIPR
*