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LSVEDWAEIRRLHRAEGLPIKMIARTLGISRNTVRAALASEGPPKYERKPAGSAVDAFEDAIRVELKKTP TMPATVIAERVGWTRGMTVFSERVRELRPAYLPPDPAGRTSYDPGDIAQCDLWFPPTTIPVGYGQTRTPT QLPVLTMVLGYSRWLSAILLPSRRAEDLFAGWWQLIAALGAVPRTLVWDGEGAIGRNRGGRIELTRDCQA FRGVLGTKVVVLKPAEPEHKGIIERAHDYFERSFLPGREFNGPGDFNHQFSKWLHVVNARRRRVLGCAPT DRIGADLAAMLALPPVPPQVGWRNSTRLARDHYVRLDSNDYSVHPGVIGRRIEVVADLDRVQVFCEGKTV AEHERVWAWHQTITDPEHREAANMLRRNRISALRPVTDSDQQVLVEQRRLSDYDAALGIDLGEGGLVS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0482 | - | - | 100% (419) | integrase catalytic subunit |
| M. vanbaalenii PYR-1 | Mvan_3900 | - | 3e-98 | 47.92% (409) | integrase catalytic subunit |
| M. vanbaalenii PYR-1 | Mvan_5931 | - | 7e-09 | 25.56% (356) | transposase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2968 | - | 1e-169 | 69.64% (415) | IS1533 transposase |
| M. gilvum PYR-GCK | Mflv_0578 | - | 2e-81 | 100.00% (145) | integrase, catalytic region |
| M. tuberculosis H37Rv | Rv2943 | - | 1e-169 | 69.64% (415) | IS1533 transposase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_3533 | - | 3e-11 | 24.86% (358) | transposase |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_3774 | - | 5e-11 | 25.90% (251) | PUTATIVE transposase IstA protein, putative |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0482|M.vanbaalenii_PYR-1 MLSVEDWAEIRRLHRAEGLPIKMIARTLGISRNTVRAALASEGPP---KY
Mflv_0578|M.gilvum_PYR-GCK --------------------------------------------------
Mb2968|M.bovis_AF2122/97 MLTVEDWAEIRRLHRAEGLPIKMIARVLGISKNTVKSALESNQQP---KY
Rv2943|M.tuberculosis_H37Rv MLTVEDWAEIRRLHRAEGLPIKMIARVLGISKNTVKSALESNQQP---KY
MAV_3533|M.avium_104 MNIISAYHQVGSYRGAA----ELCGTTHKTVKRVIERAEAGGAPP---RE
TH_3774|M.thermoresistible__bu MLTWEDDVEVHALAKRG-WTISAIARHTGFDRKTVRKYLAGDGTPGVRAR
Mvan_0482|M.vanbaalenii_PYR-1 ER-KPAGSAVDAFEDAIRVELKKTPTMPATVIAER-VGWTRGMTVFSERV
Mflv_0578|M.gilvum_PYR-GCK --------------------------------------------------
Mb2968|M.bovis_AF2122/97 ER-APQGSIVDAVEPRIRELLQAYPTMPATVIAER-IGWERSIRVLSARV
Rv2943|M.tuberculosis_H37Rv ER-APQGSIVDAVEPRIRELLQAYPTMPATVIAER-IGWERSIRVLSARV
MAV_3533|M.avium_104 PRPRNLDAFTDLVATRVEKSHGKMSAKRMLPIARA-AGYQGSARNFRRLV
TH_3774|M.thermoresistible__bu PGPDPFDPFVDYVTARLTEDPHLWARTLFDELEDLGFGLSYQSLTRNIRT
Mvan_0482|M.vanbaalenii_PYR-1 RELRPAYLPPDPAG-RTSYDPGDIAQCDLWFPPTTIPVGYGQTRTPTQLP
Mflv_0578|M.gilvum_PYR-GCK --------------------------------------------------
Mb2968|M.bovis_AF2122/97 AELRPVYLPPDPAS-RTTYVAGEIAQCDFWFPPIELPVGFGQTRTAKQLP
Rv2943|M.tuberculosis_H37Rv AELRPVYLPPDPAS-RTTYVAGEIAQCDFWFPPIELPVGFGQTRTAKQLP
MAV_3533|M.avium_104 AEQKVLWRNANRHQ-RRP---------AVWSPGDYLVMDWAEAAPG--LM
TH_3774|M.thermoresistible__bu RNLRPVCEACRTATGRPNAVIPHPPGEETQWDWLELPDPPASWGWGKTAH
Mvan_0482|M.vanbaalenii_PYR-1 VLTMVLGYSRWLSAILLPSRRAEDLFAGWWQLIAALGAVPRTLVWDGEGA
Mflv_0578|M.gilvum_PYR-GCK --------------------------------------------------
Mb2968|M.bovis_AF2122/97 VLTMVCAYSRWLLAMLLPSRCAEDLFAGWWRLIEALGAVPRVLVWDGEGA
Rv2943|M.tuberculosis_H37Rv VLTMVCAYSRWLLAMLLPSRCAEDLFAGWWRLIEALGAVPRVLVWDGEGA
MAV_3533|M.avium_104 VFCAVLAYSRWRFVRFAADEKASTTLAMIAEALEAIGGVPAKILADRMGC
TH_3774|M.thermoresistible__bu LLVGSLSHSGKWRGNLAPSEDQPHLVAGLDRVTRGLGGLTRVWRFDRMAT
Mvan_0482|M.vanbaalenii_PYR-1 IGRNRGGRIELTR-DCQAFRGVLGTKVVVLKPAEPEHKGIIERAHDYFER
Mflv_0578|M.gilvum_PYR-GCK --------------------------------------------------
Mb2968|M.bovis_AF2122/97 IGRWRGGRSELTT-ECQAFRGTLAAKVLICRPADPEAKGLIERAHDYLER
Rv2943|M.tuberculosis_H37Rv IGRWRGGRSELTT-ECQAFRGTLAAKVLICRPADPEAKGLIERAHDYLER
MAV_3533|M.avium_104 LKGGVVANVVVPTPDYVRFASHYGFVPDFCHGADPQSKGIVENLCGYAQD
TH_3774|M.thermoresistible__bu VCDPGSGR---VTASFAGVAKHYGVSVAICPPRRGNRKGVVEKVNHTAAQ
Mvan_0482|M.vanbaalenii_PYR-1 SFLPGREFNGPGD--------FNHQFSKWLHVVNARRRRVLGCAP-----
Mflv_0578|M.gilvum_PYR-GCK ---------------------------------------MLGCAP-----
Mb2968|M.bovis_AF2122/97 SFLPGRVFASPAD--------FNAQLGAWLALVNTRTRRALGCAP-----
Rv2943|M.tuberculosis_H37Rv SFLPGRVFASPAD--------FNAQLGAWLALVNTRTRRALGCAP-----
MAV_3533|M.avium_104 DLAVPLLTEAALAGEQVDLRALNAQAQLWCAEVNATVHSEICAVP-----
TH_3774|M.thermoresistible__bu RWWRTLADDLTVEAAQASLDRFARVRGDTRLRATADGRSSVAVVAXIYVR
: ..
Mvan_0482|M.vanbaalenii_PYR-1 ----------------------------TDRIGADLAAMLALPPVPPQVG
Mflv_0578|M.gilvum_PYR-GCK ----------------------------TDRIGADLAAMLALPPVPPQVG
Mb2968|M.bovis_AF2122/97 ----------------------------TDRIGADRAAMLSLPPVAPATG
Rv2943|M.tuberculosis_H37Rv ----------------------------TDRIGADRAAMLSLPPVAPATG
MAV_3533|M.avium_104 ----------------------------NDRLVDERTVLRELPSLRPTIG
TH_3774|M.thermoresistible__bu TAEQWVGVCPGCMVRSGVCPGCMVRSARSKGWVSTRPRDIKIGPDIPRIV
.. . : . *
Mvan_0482|M.vanbaalenii_PYR-1 -WRNSTRLARDHYVRLDSNDYSVHPGVIGRRIEVVADLDRVQVFC--EGK
Mflv_0578|M.gilvum_PYR-GCK -WRNSTRLARDHYVRLDSNDYSVHPGVIGRRIEVVADLDRVQVFC--EGK
Mb2968|M.bovis_AF2122/97 -WCTSLRLPRDHYVRCDSNDYSVHPGVIGHRVLVRADLERVHVFC--DGE
Rv2943|M.tuberculosis_H37Rv -WCTSLRLPRDHYVRCDSNDYSVHPGVIGHRVLVRADLERVHVFC--DGE
MAV_3533|M.avium_104 SGSVRRKVDGLSCIRYGSARYSVPQRLVGATVAVVVDHGALILLEPATGV
TH_3774|M.thermoresistible__bu -WRKRKWVCANMCCDRKSFTESVPSIPPRARVTVRAKREMASAVLDDDRS
: * ** : * .. .
Mvan_0482|M.vanbaalenii_PYR-1 TVAEHERVWAWHQTITDPEHREAANMLRR-----------------NRIS
Mflv_0578|M.gilvum_PYR-GCK TVAEHERVWAWHQTITDPEHREAANMLRR-----------------NRIS
Mb2968|M.bovis_AF2122/97 LVADHERIWAVHQTVSDPAHVEAAKVLRR-----------------RHFS
Rv2943|M.tuberculosis_H37Rv LVADHERIWAVHQTVSDPAHVEAAKVLRR-----------------RHFS
MAV_3533|M.avium_104 IVAEHELVSPGEVSILDEHYDGPRPAPSRGPRPKTQA--------EKRFC
TH_3774|M.thermoresistible__bu VKAVAAAYGCTWNTCHDAVIATADPVLAGEPEAVSVLGIDETRRGKAKWE
* : * . :
Mvan_0482|M.vanbaalenii_PYR-1 ALRPVTDSDQQ---VLVEQRRLSDYDAALGIDLGEGGLVS----------
Mflv_0578|M.gilvum_PYR-GCK ALRPVTDSDQQ---VLVEQRRLSDYDAALGIDLGEGGLVS----------
Mb2968|M.bovis_AF2122/97 AASPVVEP-------QVQVRSLSDYDDALGVDIDGG--VA----------
Rv2943|M.tuberculosis_H37Rv AASPVVEP-------QVQVRSLSDYDDALGVDIDGG--VA----------
MAV_3533|M.avium_104 ALGTEAQQFLVGAAAIGNTRLKSELDILLGLGAAHGEQALIDALRRAVAF
TH_3774|M.thermoresistible__bu TCSQTGTRSWVDRFDTGLVDITGTGGLLVQVNGRAAKPVTDWLDQRDPGW
: . . : :. . .
Mvan_0482|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0578|M.gilvum_PYR-GCK --------------------------------------------------
Mb2968|M.bovis_AF2122/97 --------------------------------------------------
Rv2943|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3533|M.avium_104 RRFRAADVRSILAAGAGTPQPRPAGDALVLDLPTVETRSLEAYKINTTDG
TH_3774|M.thermoresistible__bu KATIEFVAIDMSVTYANAARQALPHAKLIVDRFHLVKRANEMVDEVRRRT
Mvan_0482|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0578|M.gilvum_PYR-GCK --------------------------------------------------
Mb2968|M.bovis_AF2122/97 --------------------------------------------------
Rv2943|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3533|M.avium_104 TAS-----------------------------------------------
TH_3774|M.thermoresistible__bu TQAHRLRRGRKSDPEWINRRRLLRAAERLTDEQRHKLFVKLTSADPNGDI
Mvan_0482|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0578|M.gilvum_PYR-GCK --------------------------------------------------
Mb2968|M.bovis_AF2122/97 --------------------------------------------------
Rv2943|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3533|M.avium_104 --------------------------------------------------
TH_3774|M.thermoresistible__bu AAAWIAKELLRDVLACTARGGLTYEIRDALYRFYTFCAACSVPEISKLAR
Mvan_0482|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0578|M.gilvum_PYR-GCK --------------------------------------------------
Mb2968|M.bovis_AF2122/97 --------------------------------------------------
Rv2943|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3533|M.avium_104 --------------------------------------------------
TH_3774|M.thermoresistible__bu TISAWQEPMILAIQTGLSNARSEGYNRIIKHVGRIAFGFRNPENQRRRVR
Mvan_0482|M.vanbaalenii_PYR-1 --------------------
Mflv_0578|M.gilvum_PYR-GCK --------------------
Mb2968|M.bovis_AF2122/97 --------------------
Rv2943|M.tuberculosis_H37Rv --------------------
MAV_3533|M.avium_104 --------------------
TH_3774|M.thermoresistible__bu WACTRQSRRTPPSTKQVRPC