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MPTGPTTGKWHPHEVWRYLLEVLLLTDEADLESALPELESFAQSVQRAPLDDPGAAKGADADVAIIDARA DLAAARRVCRRLTTSAPALAVVAVVAPANFVAVDGDWIFDDVLLNAAGGAELQARLRLAITRRRSTLAGT LQFGDLVLHPASYTASLGDRDLGLTLTEFKLMNFLVQHAGRAFTRTRLMREVWGYECHGRIRTVDVHVRR LRAKLGAEHESMIDTVRGVGYMAVTPPQPRWIISESILNRCK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2884 | - | - | 100% (252) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. tuberculosis H37Rv | Rv0818 | - | 2e-53 | 47.35% (226) | transcriptional regulatory protein |
| M. tuberculosis H37Rv | Rv1033c | trcR | 2e-18 | 39.10% (133) | two component transcriptional regulator TRCR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2908 | - | 1e-144 | 100.00% (252) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_1650 | - | 4e-55 | 50.67% (225) | response regulator receiver protein |
| M. leprae Br4923 | MLBr_00174 | - | 2e-18 | 33.88% (183) | putative two-component response regulator |
| M. abscessus ATCC 19977 | MAB_0744 | - | 1e-54 | 49.33% (225) | transcriptional regulatory protein |
| M. marinum M | MMAR_1825 | - | 4e-86 | 66.39% (238) | transcriptional regulatory protein |
| M. avium 104 | MAV_3735 | - | 2e-77 | 64.73% (224) | transcriptional regulator GlnR |
| M. smegmatis MC2 155 | MSMEG_5784 | - | 5e-54 | 49.77% (221) | transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_4312 | - | 5e-18 | 29.39% (228) | PUTATIVE two component transcriptional regulator, winged helix |
| M. ulcerans Agy99 | MUL_2073 | - | 1e-80 | 65.04% (226) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_5097 | - | 1e-54 | 50.22% (225) | response regulator receiver protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2884|M.tuberculosis_H37Rv MPTGPTTGKWHPHEVWRYLLEVLLLTDEADLESALP---ELESFAQSVQR
Mb2908|M.bovis_AF2122/97 MPTGPTTGKWHPHEVWRYLLEVLLLTDEADLESALP---ELESFAQSVQR
MMAR_1825|M.marinum_M MRTGVAG---TPRGVGRCFLRVLLLSNAADFESTLP---TLKSFASVIQH
MUL_2073|M.ulcerans_Agy99 -----------------------MLSNAADFESTLP---TLKSFASVIQH
MAV_3735|M.avium_104 -----------------MSLDVVVLTNEDDFESALP---DLSRFARPARR
Mflv_1650|M.gilvum_PYR-GCK ----MRCPGERAPRLLEGQLDLLLLTVDPHPESVLP---SLSLLAHAVRT
Mvan_5097|M.vanbaalenii_PYR-1 -------------------MDLLLLTVDPHPESVLP---SLALLAHNVRT
MSMEG_5784|M.smegmatis_MC2_155 -------------------MDLLLLTVDPHPESVLP---SLSLLAHTVRT
MAB_0744|M.abscessus_ATCC_1997 --------------MLEGSLDLLLLTADPNPDGVLP---SLSLLAHTVRP
MLBr_00174|M.leprae_Br4923 -------------------MRILAVDDDRAVRESLRRSLSFNGYSVELAN
TH_4312|M.thermoresistible__bu ------------------MTSVLIVEDEESLADPLAFLLRKEGFETTIVT
: *
Rv2884|M.tuberculosis_H37Rv APLDDPGAAKGADADVAIIDARADLAAARRVCRRLTTSAPALAVVAVVAP
Mb2908|M.bovis_AF2122/97 APLDDPGAAKGADADVAIIDARADLAAARRVCRRLTTSAPALAVVAVVAP
MMAR_1825|M.marinum_M ARLDAAGPPDWAGPDVAMIDARSDLATARSTCRRLTANAPSVAVVAVVAA
MUL_2073|M.ulcerans_Agy99 ARLDAADPPDWAGPDVAMIDARSDLTTARSACRRLTANAPSVAVVAVVAA
MAV_3735|M.avium_104 AALSTDGDGQFGPADVAIIDARSNVAAAQAVSHRLTADHPATAVVALVAP
Mflv_1650|M.gilvum_PYR-GCK APTEVSSLLEAGTADVAIVDARTDLAAARGLCRLLGTTGTSVPVVAVVNE
Mvan_5097|M.vanbaalenii_PYR-1 APTEVSSLLEAGTADVAIVDARTDLAAARGLCRLLGTTGTSVPVVAVVNE
MSMEG_5784|M.smegmatis_MC2_155 APTEVSSLLETGSADVAIVDARTDLAAARGLCRLLGTTGTSVPVVAVINE
MAB_0744|M.abscessus_ATCC_1997 VPSEVSSLLEAGAADVAIVDARTDLASARGLCRLLGAAGSSVPVVAVVNE
MLBr_00174|M.leprae_Br4923 DGVEALEMVARDRPDALVLDVMMPRLDGLEVCRQLRSTGDDLPILVLTAR
TH_4312|M.thermoresistible__bu DGPSALAEFERSGADIILLDLMLPGMSGTDVCRRLRAK-SKVPVIMVTAR
. .* ::* . .: * : .:: :
Rv2884|M.tuberculosis_H37Rv AN--FVAVDGDWIFDDVLLNAAGGAELQARLRLAITRRRS-TLA----GT
Mb2908|M.bovis_AF2122/97 AN--FVAVDGDWIFDDVLLNAAGGAELQARLRLAITRRRS-TLA----GT
MMAR_1825|M.marinum_M AD--FVDIDIDWHFDDVLLAAAGAAELRARLRLAVTRRRR-ARK----GT
MUL_2073|M.ulcerans_Agy99 AD--FVDIDIDWHFDDVLLAAAGAAELRARLRLAVMRRRR-ARK----GT
MAV_3735|M.avium_104 AD--CAAVDVDCNFDDVMLPGTCAEELQARLRLAIGRRRG-GLD----GT
Mflv_1650|M.gilvum_PYR-GCK GG--LVAVNVEWGLDEILLPSTGPAEIDARLRLLVGRRGG-MANQENLGK
Mvan_5097|M.vanbaalenii_PYR-1 GG--LVAVNVEWGLDEILLPSTGPAEIDARLRLLVGRRGG-MANQENLGK
MSMEG_5784|M.smegmatis_MC2_155 GG--LVAVNHEWGLDEILLPSTGPAEIDARLRLLVGRRGG-NANQENVGK
MAB_0744|M.abscessus_ATCC_1997 GS--LVAVNVDWGLDDILLPGTGPAEIDARLRLLVGRRAG-AVNVENASK
MLBr_00174|M.leprae_Br4923 DSVSERVAGLDAGADDYLPKPFALEELLARIRALLRRTKPDDAAES--VA
TH_4312|M.thermoresistible__bu DSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGSDLDGADVDDSV
. . : *: : *: **:* : *
Rv2884|M.tuberculosis_H37Rv LQFGDLVLHPASYTASLGDRDLGLTLTEFKLMNFLVQHAGRAFTRTRLMR
Mb2908|M.bovis_AF2122/97 LQFGDLVLHPASYTASLGDRDLGLTLTEFKLMNFLVQHAGRAFTRTRLMR
MMAR_1825|M.marinum_M LEFGDLAIHPDSCTVTVAGEALGLTLTEFRLFHFLVRHAGQAFTRTRLMH
MUL_2073|M.ulcerans_Agy99 LEFGDLAIHPDSCTVTVAGEALGLTLTEFRLFHFLVRHAGQAFTHTRLMH
MAV_3735|M.avium_104 LKFGDLLLHPASFTASLDGRELNLTLTEFKLLNFLVQHAGQAFTRTRLMQ
Mflv_1650|M.gilvum_PYR-GCK ISLGELVIDEGTYTARLRGRPLDLTYKEFELLKYLAQHAGRVFTRAQLLQ
Mvan_5097|M.vanbaalenii_PYR-1 ISLGELVIDEGTYTARLRGRPLDLTYKEFELLKYLAQHAGRVFTRAQLLQ
MSMEG_5784|M.smegmatis_MC2_155 ITLGELVIDEGTYTARLRGKPLDLTYKEFELLKYLAQHAGRVFTRAQLLQ
MAB_0744|M.abscessus_ATCC_1997 VVLGELVIDEGTYTARLRGRPLDLTYKEFELLKYLAQHAGRVFTRAQLLQ
MLBr_00174|M.leprae_Br4923 MSFSDLTLDPVTREVARGQRWISLTRTEFALLEMLIANPRRVLTRSRILE
TH_4312|M.thermoresistible__bu LEAGPVRMDVDRHVVTVRGEPITLPLKEFELLEYLLRNSGRVLTRGQLID
: . : :. . . : *. .** *:. * :. :.:*: :::
Rv2884|M.tuberculosis_H37Rv EVWGYECHGRIRTVDVHVRRLRAKLGAE--HESMIDTVRGVGYMAVTPPQ
Mb2908|M.bovis_AF2122/97 EVWGYECHGRIRTVDVHVRRLRAKLGAE--HESMIDTVRGVGYMAVTPPQ
MMAR_1825|M.marinum_M EVWGYDCNGRARTVDVHVRRLRAKLGAD--HESMVDTVRGVGYMAVTPPL
MUL_2073|M.ulcerans_Agy99 EVWGYDCNGRARTVDVHVRRLRAKLGAD--HESMVDTERGVGYMAVTPPP
MAV_3735|M.avium_104 QAWGYEGNGRARTVDVHIRRLRAKLGTR--HQSLVGTVRGVGYRVPTPPQ
Mflv_1650|M.gilvum_PYR-GCK EVWGYDFFGGTRTVDVHVRRLRAKLGPE--YESLIGTVRNVGYKAVRPAR
Mvan_5097|M.vanbaalenii_PYR-1 EVWGYDFFGGTRTVDVHVRRLRAKLGPE--YEALIGTVRNVGYKAVRPAR
MSMEG_5784|M.smegmatis_MC2_155 EVWGYDFFGGTRTVDVHVRRLRAKLGPE--YEALIGTVRNVGYKAVRPSR
MAB_0744|M.abscessus_ATCC_1997 EVWGYDFFGGTRTVDVHVRRLRAKLGGE--YESLIGTVRNVGYKAVRPPR
MLBr_00174|M.leprae_Br4923 EVWGFDFPTSGNALEVYVGYLRRKTEAD-GESRLIHTVRGVGYVLRETPP
TH_4312|M.thermoresistible__bu RVWGADYVGDTKTLDVHVKRLRSKIEEDPANPVHLVTVRGLGYKLEG---
..** : .:::*:: ** * : * *.:**
Rv2884|M.tuberculosis_H37Rv PRWIISESILNRCK-------------------------------
Mb2908|M.bovis_AF2122/97 PRWIISESILNRCK-------------------------------
MMAR_1825|M.marinum_M PRWTARQPVLSPGSGPEPQDISVPTEQVLAR--------------
MUL_2073|M.ulcerans_Agy99 PRWTARQPVLSPGSGPEPQDISVPTEQVLVR--------------
MAV_3735|M.avium_104 PEWIVGHQKP-----------------------------------
Mflv_1650|M.gilvum_PYR-GCK GR-PPAP--ESEADDLD-DDPYADDE-PLASDEVPQALGDALRSP
Mvan_5097|M.vanbaalenii_PYR-1 GR-APAAGADLPSDDLDGDDPYEDGVGSLDRDGVPEALGDALRSQ
MSMEG_5784|M.smegmatis_MC2_155 GK-PPAA--DASGEDVP-DGPDEGFG---DDVDVDGPLAGRLTSQ
MAB_0744|M.abscessus_ATCC_1997 AKGEPGPSAADDDDESDIDDLDDDGT----DQDIASEPG-AINAG
MLBr_00174|M.leprae_Br4923 ---------------------------------------------
TH_4312|M.thermoresistible__bu ---------------------------------------------