For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MPTGPTTGKWHPHEVWRYLLEVLLLTDEADLESALPELESFAQSVQRAPLDDPGAAKGADADVAIIDARA DLAAARRVCRRLTTSAPALAVVAVVAPANFVAVDGDWIFDDVLLNAAGGAELQARLRLAITRRRSTLAGT LQFGDLVLHPASYTASLGDRDLGLTLTEFKLMNFLVQHAGRAFTRTRLMREVWGYECHGRIRTVDVHVRR LRAKLGAEHESMIDTVRGVGYMAVTPPQPRWIISESILNRCK
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2908 | - | - | 100% (252) | transcriptional regulatory protein |
M. bovis AF2122 / 97 | Mb0841 | - | 2e-53 | 47.35% (226) | transcriptional regulatory protein |
M. bovis AF2122 / 97 | Mb1062c | trcR | 2e-18 | 39.10% (133) | two component transcriptional regulator TRCR |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_1650 | - | 4e-55 | 50.67% (225) | response regulator receiver protein |
M. tuberculosis H37Rv | Rv2884 | - | 1e-144 | 100.00% (252) | transcriptional regulatory protein |
M. leprae Br4923 | MLBr_00174 | - | 2e-18 | 33.88% (183) | putative two-component response regulator |
M. abscessus ATCC 19977 | MAB_0744 | - | 1e-54 | 49.33% (225) | transcriptional regulatory protein |
M. marinum M | MMAR_1825 | - | 4e-86 | 66.39% (238) | transcriptional regulatory protein |
M. avium 104 | MAV_3735 | - | 2e-77 | 64.73% (224) | transcriptional regulator GlnR |
M. smegmatis MC2 155 | MSMEG_5784 | - | 5e-54 | 49.77% (221) | transcriptional regulatory protein |
M. thermoresistible (build 8) | TH_4312 | - | 5e-18 | 29.39% (228) | PUTATIVE two component transcriptional regulator, winged helix |
M. ulcerans Agy99 | MUL_2073 | - | 1e-80 | 65.04% (226) | transcriptional regulatory protein |
M. vanbaalenii PYR-1 | Mvan_5097 | - | 1e-54 | 50.22% (225) | response regulator receiver protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb2908|M.bovis_AF2122/97 MPTGPTTGKWHPHEVWRYLLEVLLLTDEADLESALP---ELESFAQSVQR Rv2884|M.tuberculosis_H37Rv MPTGPTTGKWHPHEVWRYLLEVLLLTDEADLESALP---ELESFAQSVQR MMAR_1825|M.marinum_M MRTGVAG---TPRGVGRCFLRVLLLSNAADFESTLP---TLKSFASVIQH MUL_2073|M.ulcerans_Agy99 -----------------------MLSNAADFESTLP---TLKSFASVIQH MAV_3735|M.avium_104 -----------------MSLDVVVLTNEDDFESALP---DLSRFARPARR Mflv_1650|M.gilvum_PYR-GCK ----MRCPGERAPRLLEGQLDLLLLTVDPHPESVLP---SLSLLAHAVRT Mvan_5097|M.vanbaalenii_PYR-1 -------------------MDLLLLTVDPHPESVLP---SLALLAHNVRT MSMEG_5784|M.smegmatis_MC2_155 -------------------MDLLLLTVDPHPESVLP---SLSLLAHTVRT MAB_0744|M.abscessus_ATCC_1997 --------------MLEGSLDLLLLTADPNPDGVLP---SLSLLAHTVRP MLBr_00174|M.leprae_Br4923 -------------------MRILAVDDDRAVRESLRRSLSFNGYSVELAN TH_4312|M.thermoresistible__bu ------------------MTSVLIVEDEESLADPLAFLLRKEGFETTIVT : * Mb2908|M.bovis_AF2122/97 APLDDPGAAKGADADVAIIDARADLAAARRVCRRLTTSAPALAVVAVVAP Rv2884|M.tuberculosis_H37Rv APLDDPGAAKGADADVAIIDARADLAAARRVCRRLTTSAPALAVVAVVAP MMAR_1825|M.marinum_M ARLDAAGPPDWAGPDVAMIDARSDLATARSTCRRLTANAPSVAVVAVVAA MUL_2073|M.ulcerans_Agy99 ARLDAADPPDWAGPDVAMIDARSDLTTARSACRRLTANAPSVAVVAVVAA MAV_3735|M.avium_104 AALSTDGDGQFGPADVAIIDARSNVAAAQAVSHRLTADHPATAVVALVAP Mflv_1650|M.gilvum_PYR-GCK APTEVSSLLEAGTADVAIVDARTDLAAARGLCRLLGTTGTSVPVVAVVNE Mvan_5097|M.vanbaalenii_PYR-1 APTEVSSLLEAGTADVAIVDARTDLAAARGLCRLLGTTGTSVPVVAVVNE MSMEG_5784|M.smegmatis_MC2_155 APTEVSSLLETGSADVAIVDARTDLAAARGLCRLLGTTGTSVPVVAVINE MAB_0744|M.abscessus_ATCC_1997 VPSEVSSLLEAGAADVAIVDARTDLASARGLCRLLGAAGSSVPVVAVVNE MLBr_00174|M.leprae_Br4923 DGVEALEMVARDRPDALVLDVMMPRLDGLEVCRQLRSTGDDLPILVLTAR TH_4312|M.thermoresistible__bu DGPSALAEFERSGADIILLDLMLPGMSGTDVCRRLRAK-SKVPVIMVTAR . .* ::* . .: * : .:: : Mb2908|M.bovis_AF2122/97 AN--FVAVDGDWIFDDVLLNAAGGAELQARLRLAITRRRS-TLA----GT Rv2884|M.tuberculosis_H37Rv AN--FVAVDGDWIFDDVLLNAAGGAELQARLRLAITRRRS-TLA----GT MMAR_1825|M.marinum_M AD--FVDIDIDWHFDDVLLAAAGAAELRARLRLAVTRRRR-ARK----GT MUL_2073|M.ulcerans_Agy99 AD--FVDIDIDWHFDDVLLAAAGAAELRARLRLAVMRRRR-ARK----GT MAV_3735|M.avium_104 AD--CAAVDVDCNFDDVMLPGTCAEELQARLRLAIGRRRG-GLD----GT Mflv_1650|M.gilvum_PYR-GCK GG--LVAVNVEWGLDEILLPSTGPAEIDARLRLLVGRRGG-MANQENLGK Mvan_5097|M.vanbaalenii_PYR-1 GG--LVAVNVEWGLDEILLPSTGPAEIDARLRLLVGRRGG-MANQENLGK MSMEG_5784|M.smegmatis_MC2_155 GG--LVAVNHEWGLDEILLPSTGPAEIDARLRLLVGRRGG-NANQENVGK MAB_0744|M.abscessus_ATCC_1997 GS--LVAVNVDWGLDDILLPGTGPAEIDARLRLLVGRRAG-AVNVENASK MLBr_00174|M.leprae_Br4923 DSVSERVAGLDAGADDYLPKPFALEELLARIRALLRRTKPDDAAES--VA TH_4312|M.thermoresistible__bu DSEIDKVVGLELGADDYVTKPYSARELIARIRAVLRRGSDLDGADVDDSV . . : *: : *: **:* : * Mb2908|M.bovis_AF2122/97 LQFGDLVLHPASYTASLGDRDLGLTLTEFKLMNFLVQHAGRAFTRTRLMR Rv2884|M.tuberculosis_H37Rv LQFGDLVLHPASYTASLGDRDLGLTLTEFKLMNFLVQHAGRAFTRTRLMR MMAR_1825|M.marinum_M LEFGDLAIHPDSCTVTVAGEALGLTLTEFRLFHFLVRHAGQAFTRTRLMH MUL_2073|M.ulcerans_Agy99 LEFGDLAIHPDSCTVTVAGEALGLTLTEFRLFHFLVRHAGQAFTHTRLMH MAV_3735|M.avium_104 LKFGDLLLHPASFTASLDGRELNLTLTEFKLLNFLVQHAGQAFTRTRLMQ Mflv_1650|M.gilvum_PYR-GCK ISLGELVIDEGTYTARLRGRPLDLTYKEFELLKYLAQHAGRVFTRAQLLQ Mvan_5097|M.vanbaalenii_PYR-1 ISLGELVIDEGTYTARLRGRPLDLTYKEFELLKYLAQHAGRVFTRAQLLQ MSMEG_5784|M.smegmatis_MC2_155 ITLGELVIDEGTYTARLRGKPLDLTYKEFELLKYLAQHAGRVFTRAQLLQ MAB_0744|M.abscessus_ATCC_1997 VVLGELVIDEGTYTARLRGRPLDLTYKEFELLKYLAQHAGRVFTRAQLLQ MLBr_00174|M.leprae_Br4923 MSFSDLTLDPVTREVARGQRWISLTRTEFALLEMLIANPRRVLTRSRILE TH_4312|M.thermoresistible__bu LEAGPVRMDVDRHVVTVRGEPITLPLKEFELLEYLLRNSGRVLTRGQLID : . : :. . . : *. .** *:. * :. :.:*: ::: Mb2908|M.bovis_AF2122/97 EVWGYECHGRIRTVDVHVRRLRAKLGAE--HESMIDTVRGVGYMAVTPPQ Rv2884|M.tuberculosis_H37Rv EVWGYECHGRIRTVDVHVRRLRAKLGAE--HESMIDTVRGVGYMAVTPPQ MMAR_1825|M.marinum_M EVWGYDCNGRARTVDVHVRRLRAKLGAD--HESMVDTVRGVGYMAVTPPL MUL_2073|M.ulcerans_Agy99 EVWGYDCNGRARTVDVHVRRLRAKLGAD--HESMVDTERGVGYMAVTPPP MAV_3735|M.avium_104 QAWGYEGNGRARTVDVHIRRLRAKLGTR--HQSLVGTVRGVGYRVPTPPQ Mflv_1650|M.gilvum_PYR-GCK EVWGYDFFGGTRTVDVHVRRLRAKLGPE--YESLIGTVRNVGYKAVRPAR Mvan_5097|M.vanbaalenii_PYR-1 EVWGYDFFGGTRTVDVHVRRLRAKLGPE--YEALIGTVRNVGYKAVRPAR MSMEG_5784|M.smegmatis_MC2_155 EVWGYDFFGGTRTVDVHVRRLRAKLGPE--YEALIGTVRNVGYKAVRPSR MAB_0744|M.abscessus_ATCC_1997 EVWGYDFFGGTRTVDVHVRRLRAKLGGE--YESLIGTVRNVGYKAVRPPR MLBr_00174|M.leprae_Br4923 EVWGFDFPTSGNALEVYVGYLRRKTEAD-GESRLIHTVRGVGYVLRETPP TH_4312|M.thermoresistible__bu RVWGADYVGDTKTLDVHVKRLRSKIEEDPANPVHLVTVRGLGYKLEG--- ..** : .:::*:: ** * : * *.:** Mb2908|M.bovis_AF2122/97 PRWIISESILNRCK------------------------------- Rv2884|M.tuberculosis_H37Rv PRWIISESILNRCK------------------------------- MMAR_1825|M.marinum_M PRWTARQPVLSPGSGPEPQDISVPTEQVLAR-------------- MUL_2073|M.ulcerans_Agy99 PRWTARQPVLSPGSGPEPQDISVPTEQVLVR-------------- MAV_3735|M.avium_104 PEWIVGHQKP----------------------------------- Mflv_1650|M.gilvum_PYR-GCK GR-PPAP--ESEADDLD-DDPYADDE-PLASDEVPQALGDALRSP Mvan_5097|M.vanbaalenii_PYR-1 GR-APAAGADLPSDDLDGDDPYEDGVGSLDRDGVPEALGDALRSQ MSMEG_5784|M.smegmatis_MC2_155 GK-PPAA--DASGEDVP-DGPDEGFG---DDVDVDGPLAGRLTSQ MAB_0744|M.abscessus_ATCC_1997 AKGEPGPSAADDDDESDIDDLDDDGT----DQDIASEPG-AINAG MLBr_00174|M.leprae_Br4923 --------------------------------------------- TH_4312|M.thermoresistible__bu ---------------------------------------------