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MSLDVVVLTNEDDFESALPDLSRFARPARRAALSTDGDGQFGPADVAIIDARSNVAAAQAVSHRLTADHP ATAVVALVAPADCAAVDVDCNFDDVMLPGTCAEELQARLRLAIGRRRGGLDGTLKFGDLLLHPASFTASL DGRELNLTLTEFKLLNFLVQHAGQAFTRTRLMQQAWGYEGNGRARTVDVHIRRLRAKLGTRHQSLVGTVR GVGYRVPTPPQPEWIVGHQKP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3735 | - | - | 100% (231) | transcriptional regulator GlnR |
| M. avium 104 | MAV_0760 | - | 3e-44 | 41.63% (221) | transcriptional regulatory protein |
| M. avium 104 | MAV_4660 | - | 6e-18 | 28.57% (224) | DNA-binding response regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2908 | - | 2e-77 | 64.73% (224) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_1650 | - | 9e-49 | 44.78% (230) | response regulator receiver protein |
| M. tuberculosis H37Rv | Rv2884 | - | 2e-77 | 64.73% (224) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_02439 | - | 2e-17 | 33.54% (161) | putative two-component system response regulator |
| M. abscessus ATCC 19977 | MAB_0744 | - | 4e-50 | 45.09% (224) | transcriptional regulatory protein |
| M. marinum M | MMAR_1825 | - | 2e-68 | 58.11% (222) | transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_5784 | - | 4e-47 | 43.44% (221) | transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_4312 | - | 5e-17 | 28.12% (224) | PUTATIVE two component transcriptional regulator, winged helix |
| M. ulcerans Agy99 | MUL_2073 | - | 3e-65 | 56.42% (218) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_5097 | - | 1e-47 | 44.34% (221) | response regulator receiver protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2908|M.bovis_AF2122/97 MPTGPTTGKWHPHEVWRYLLEVLLLTDEADLESALPELESFAQSVQRAPL
Rv2884|M.tuberculosis_H37Rv MPTGPTTGKWHPHEVWRYLLEVLLLTDEADLESALPELESFAQSVQRAPL
MMAR_1825|M.marinum_M MRTGVAG---TPRGVGRCFLRVLLLSNAADFESTLPTLKSFASVIQHARL
MUL_2073|M.ulcerans_Agy99 -----------------------MLSNAADFESTLPTLKSFASVIQHARL
MAV_3735|M.avium_104 -----------------MSLDVVVLTNEDDFESALPDLSRFARPARRAAL
Mflv_1650|M.gilvum_PYR-GCK ----MRCPGERAPRLLEGQLDLLLLTVDPHPESVLPSLSLLAHAVRTAPT
Mvan_5097|M.vanbaalenii_PYR-1 -------------------MDLLLLTVDPHPESVLPSLALLAHNVRTAPT
MSMEG_5784|M.smegmatis_MC2_155 -------------------MDLLLLTVDPHPESVLPSLSLLAHTVRTAPT
MAB_0744|M.abscessus_ATCC_1997 --------------MLEGSLDLLLLTADPNPDGVLPSLSLLAHTVRPVPS
MLBr_02439|M.leprae_Br4923 --------------------------------------------MVTDGP
TH_4312|M.thermoresistible__bu ---------------MTSVLIVEDEESLADPLAFLLRKEGFETTIVTDGP
Mb2908|M.bovis_AF2122/97 DDPGAAKGADADVAIIDARADLAAARRVCRRLTTSAPALAVVAVVAPANF
Rv2884|M.tuberculosis_H37Rv DDPGAAKGADADVAIIDARADLAAARRVCRRLTTSAPALAVVAVVAPANF
MMAR_1825|M.marinum_M DAAGPPDWAGPDVAMIDARSDLATARSTCRRLTANAPSVAVVAVVAAADF
MUL_2073|M.ulcerans_Agy99 DAADPPDWAGPDVAMIDARSDLTTARSACRRLTANAPSVAVVAVVAAADF
MAV_3735|M.avium_104 STDGDGQFGPADVAIIDARSNVAAAQAVSHRLTADHPATAVVALVAPADC
Mflv_1650|M.gilvum_PYR-GCK EVSSLLEAGTADVAIVDARTDLAAARGLCRLLGTTGTSVPVVAVVNEGGL
Mvan_5097|M.vanbaalenii_PYR-1 EVSSLLEAGTADVAIVDARTDLAAARGLCRLLGTTGTSVPVVAVVNEGGL
MSMEG_5784|M.smegmatis_MC2_155 EVSSLLETGSADVAIVDARTDLAAARGLCRLLGTTGTSVPVVAVINEGGL
MAB_0744|M.abscessus_ATCC_1997 EVSSLLEAGAADVAIVDARTDLASARGLCRLLGAAGSSVPVVAVVNEGSL
MLBr_02439|M.leprae_Br4923 AALAEFDRSGADIVLLDLMLPGMSGTDVYKQLRVRSSVPVIMVTARDSEI
TH_4312|M.thermoresistible__bu SALAEFERSGADIILLDLMLPGMSGTDVCRRLRAKSKVPVIMVTARDSEI
. . .*: ::* :. : * . ::. .
Mb2908|M.bovis_AF2122/97 VAVD-GDWIFDDVLLNAAGGAELQARLRLAITR-RRSTLA----GTLQFG
Rv2884|M.tuberculosis_H37Rv VAVD-GDWIFDDVLLNAAGGAELQARLRLAITR-RRSTLA----GTLQFG
MMAR_1825|M.marinum_M VDID-IDWHFDDVLLAAAGAAELRARLRLAVTR-RRRARK----GTLEFG
MUL_2073|M.ulcerans_Agy99 VDID-IDWHFDDVLLAAAGAAELRARLRLAVMR-RRRARK----GTLEFG
MAV_3735|M.avium_104 AAVD-VDCNFDDVMLPGTCAEELQARLRLAIGR-RRGGLD----GTLKFG
Mflv_1650|M.gilvum_PYR-GCK VAVN-VEWGLDEILLPSTGPAEIDARLRLLVGR-RGGMANQENLGKISLG
Mvan_5097|M.vanbaalenii_PYR-1 VAVN-VEWGLDEILLPSTGPAEIDARLRLLVGR-RGGMANQENLGKISLG
MSMEG_5784|M.smegmatis_MC2_155 VAVN-HEWGLDEILLPSTGPAEIDARLRLLVGR-RGGNANQENVGKITLG
MAB_0744|M.abscessus_ATCC_1997 VAVN-VDWGLDDILLPGTGPAEIDARLRLLVGR-RAGAVNVENASKVVLG
MLBr_02439|M.leprae_Br4923 DKVVGLELGADDYVTKPYSARELIARIRAVLRRGGDDD-SEISDGVLESG
TH_4312|M.thermoresistible__bu DKVVGLELGADDYVTKPYSARELIARIRAVLRRGSDLDGADVDDSVLEAG
: : *: : *: **:* : * . : *
Mb2908|M.bovis_AF2122/97 DLVLHPASYTASLGDRDLGLTLTEFKLMNFLVQHAGRAFTRTRLMREVWG
Rv2884|M.tuberculosis_H37Rv DLVLHPASYTASLGDRDLGLTLTEFKLMNFLVQHAGRAFTRTRLMREVWG
MMAR_1825|M.marinum_M DLAIHPDSCTVTVAGEALGLTLTEFRLFHFLVRHAGQAFTRTRLMHEVWG
MUL_2073|M.ulcerans_Agy99 DLAIHPDSCTVTVAGEALGLTLTEFRLFHFLVRHAGQAFTHTRLMHEVWG
MAV_3735|M.avium_104 DLLLHPASFTASLDGRELNLTLTEFKLLNFLVQHAGQAFTRTRLMQQAWG
Mflv_1650|M.gilvum_PYR-GCK ELVIDEGTYTARLRGRPLDLTYKEFELLKYLAQHAGRVFTRAQLLQEVWG
Mvan_5097|M.vanbaalenii_PYR-1 ELVIDEGTYTARLRGRPLDLTYKEFELLKYLAQHAGRVFTRAQLLQEVWG
MSMEG_5784|M.smegmatis_MC2_155 ELVIDEGTYTARLRGKPLDLTYKEFELLKYLAQHAGRVFTRAQLLQEVWG
MAB_0744|M.abscessus_ATCC_1997 ELVIDEGTYTARLRGRPLDLTYKEFELLKYLAQHAGRVFTRAQLLQEVWG
MLBr_02439|M.leprae_Br4923 PLRMDVERHVVSVNGYAITLPLKEFDLLEYLMRNSGRVLTRGQLIDRVWG
TH_4312|M.thermoresistible__bu PVRMDVDRHVVTVRGEPITLPLKEFELLEYLLRNSGRVLTRGQLIDRVWG
: :. .. : . : *. .** *:.:* :::*:.:*: :*: ..**
Mb2908|M.bovis_AF2122/97 YECHGRIRTVDVHVRRLRAKLG--AEHESMIDTVRGVGYMAVTPPQPRWI
Rv2884|M.tuberculosis_H37Rv YECHGRIRTVDVHVRRLRAKLG--AEHESMIDTVRGVGYMAVTPPQPRWI
MMAR_1825|M.marinum_M YDCNGRARTVDVHVRRLRAKLG--ADHESMVDTVRGVGYMAVTPPLPRWT
MUL_2073|M.ulcerans_Agy99 YDCNGRARTVDVHVRRLRAKLG--ADHESMVDTERGVGYMAVTPPPPRWT
MAV_3735|M.avium_104 YEGNGRARTVDVHIRRLRAKLG--TRHQSLVGTVRGVGYRVPTPPQPEWI
Mflv_1650|M.gilvum_PYR-GCK YDFFGGTRTVDVHVRRLRAKLG--PEYESLIGTVRNVGYKAVRPARGR-P
Mvan_5097|M.vanbaalenii_PYR-1 YDFFGGTRTVDVHVRRLRAKLG--PEYEALIGTVRNVGYKAVRPARGR-A
MSMEG_5784|M.smegmatis_MC2_155 YDFFGGTRTVDVHVRRLRAKLG--PEYEALIGTVRNVGYKAVRPSRGK-P
MAB_0744|M.abscessus_ATCC_1997 YDFFGGTRTVDVHVRRLRAKLG--GEYESLIGTVRNVGYKAVRPPRAKGE
MLBr_02439|M.leprae_Br4923 VDYVGDTKTLDVHVKRLRSKIEADPANPVHLVTVRGLGYKLES-------
TH_4312|M.thermoresistible__bu ADYVGDTKTLDVHVKRLRSKIEEDPANPVHLVTVRGLGYKLEG-------
: * :*:***::***:*: : * *.:**
Mb2908|M.bovis_AF2122/97 ISESILNRCK-------------------------------
Rv2884|M.tuberculosis_H37Rv ISESILNRCK-------------------------------
MMAR_1825|M.marinum_M ARQPVLSPGSGPEPQDISVPTEQVLAR--------------
MUL_2073|M.ulcerans_Agy99 ARQPVLSPGSGPEPQDISVPTEQVLVR--------------
MAV_3735|M.avium_104 VGHQKP-----------------------------------
Mflv_1650|M.gilvum_PYR-GCK PAP--ESEADDLD-DDPYADDE-PLASDEVPQALGDALRSP
Mvan_5097|M.vanbaalenii_PYR-1 PAAGADLPSDDLDGDDPYEDGVGSLDRDGVPEALGDALRSQ
MSMEG_5784|M.smegmatis_MC2_155 PAA--DASGEDVP-DGPDEGFG---DDVDVDGPLAGRLTSQ
MAB_0744|M.abscessus_ATCC_1997 PGPSAADDDDESDIDDLDDDGT----DQDIASEPG-AINAG
MLBr_02439|M.leprae_Br4923 -----------------------------------------
TH_4312|M.thermoresistible__bu -----------------------------------------