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VYGALVTAADSIRTGLGASLLAGFRPRTGAPSTATILRSALWPAAVLSVLHRSIVLTTNGNITDDFKPVY RAVLNFRRGWDIYNEHFDYVDPHYLYPPGGTLLMAPFGYLPFAPSRYLFISINTAAILVAAYLLLRMFNF TLTSVAAPALILAMFATETVTNTLVFTNINGCILLLEVLFLRWLLDGRASRQWCGGLAIGLTLVLKPLLG PLLLLPLLNRQWRALVAAVVVPVVVNVAALPLVSDPMSFFTRTLPYILGTRDYFNSSILGNGVYFGLPTW LILFLRILFTAITFGALWLLYRYYRTGDPLFWFTTSSGVLLLWSWLVMSLAQGYYSMMLFPFLMTVVLPN SVIRNWPAWLGVYGFMTLDRWLLFNWMRWGRALEYLKITYGWSLLLIVTFTVLYFRYLDAKADNRLDGGI DPAWLTPEREGQR
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv2673 | - | - | 100% (433) | POSSIBLE CONSERVED INTEGRAL MEMBRANE PROTEIN |
M. tuberculosis H37Rv | Rv2181 | - | 1e-06 | 22.87% (341) | integral membrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2692 | - | 0.0 | 100.00% (433) | integral membrane protein |
M. gilvum PYR-GCK | Mflv_3915 | - | 1e-175 | 70.94% (406) | putative integral membrane protein |
M. leprae Br4923 | MLBr_01338 | - | 0.0 | 82.26% (434) | hypothetical protein MLBr_01338 |
M. abscessus ATCC 19977 | MAB_2978 | - | 1e-156 | 63.29% (425) | hypothetical protein MAB_2978 |
M. marinum M | MMAR_2043 | - | 0.0 | 88.14% (430) | transmembrane protein |
M. avium 104 | MAV_3565 | - | 0.0 | 82.56% (430) | hypothetical protein MAV_3565 |
M. smegmatis MC2 155 | MSMEG_2785 | - | 1e-178 | 69.93% (429) | putative integral membrane protein |
M. thermoresistible (build 8) | TH_0624 | - | 1e-166 | 72.26% (393) | POSSIBLE CONSERVED INTEGRAL MEMBRANE PROTEIN |
M. ulcerans Agy99 | MUL_3307 | - | 0.0 | 87.67% (430) | transmembrane protein |
M. vanbaalenii PYR-1 | Mvan_2488 | - | 1e-174 | 71.18% (406) | putative integral membrane protein |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_3915|M.gilvum_PYR-GCK -----------MLTAFR--------PRTAPPTTATVLRSILWPLAIMAVI Mvan_2488|M.vanbaalenii_PYR-1 -------MRDLVLTAFR--------PRTSPPTTASVLRSILWPLAIMAVI TH_0624|M.thermoresistible__bu -----------------------------------VLRSVLWPIAIMAVI MAB_2978|M.abscessus_ATCC_1997 -----MVSVDALVTGFKN----SLAPKTAPPSVATILRSVLWPVAIMAVI MSMEG_2785|M.smegmatis_MC2_155 MYCALVTATDSITTKLLN----AFRPRTSAPSTATVLRSVLWPIAILSVI Rv2673|M.tuberculosis_H37Rv MYGALVTAADSIRTGLGASLLAGFRPRTGAPSTATILRSALWPAAVLSVL Mb2692|M.bovis_AF2122/97 MYGALVTAADSIRTGLGASLLAGFRPRTGAPSTATILRSALWPAAVLSVL MMAR_2043|M.marinum_M MYGALVTAADSTRTGLRECMQAAFRPRTGPPSASAILRSVLWPAAILSVL MUL_3307|M.ulcerans_Agy99 MYGALVTAADSTRTGLRECMQAAFRPRTGPPSASAILRSVLWPAAILSVL MLBr_01338|M.leprae_Br4923 MYGALVTAADSTQTGLRNWLLAVFHPRTHTPSTATIVRSALWPAAILSVL MAV_3565|M.avium_104 MYGALVTAAES--TGLRDWIQAAFRPRTSAPSVATVLRSALWPIAIFSVL ::** *** *:::*: Mflv_3915|M.gilvum_PYR-GCK HRSYVLVFNRYITDDFAPVYRAVINFKFGWDIYNEHFDHVDPHYLYPPGG Mvan_2488|M.vanbaalenii_PYR-1 HRSYVLVFNRYITDDFAPVYRAVINFKFGWDIYNENFGHVDPHYLYPPGG TH_0624|M.thermoresistible__bu HRSWVLSTNRSITDDFTPVYNAAVAFLRGQPVYTANFNHVDPHFLYPPGG MAB_2978|M.abscessus_ATCC_1997 HRSYVLGTNGYITDDFGPVYRAVIAFKLHQPVYGENFNYVDPHYIYPPGG MSMEG_2785|M.smegmatis_MC2_155 HRSYVLGTNGYITDDFGPVYRAVINFKLGLDIYNEQFDHVDPHYLYPPGG Rv2673|M.tuberculosis_H37Rv HRSIVLTTNGNITDDFKPVYRAVLNFRRGWDIYNEHFDYVDPHYLYPPGG Mb2692|M.bovis_AF2122/97 HRSIVLTTNGNITDDFKPVYRAVLNFRRGWDIYNEHFDYVDPHYLYPPGG MMAR_2043|M.marinum_M HRAIVLTTNGNITDDFKPVYRAVLNFRRGWDIYNEHFDYVDPHYLYPPGG MUL_3307|M.ulcerans_Agy99 HRAIVLTTNGNITDDFKPVYRAVLNFRRGWDIYNEHFDYVDPHYLYPPGG MLBr_01338|M.leprae_Br4923 HRSTVITTNGNITDDFKPVYRAVLNFRHGWDIYNEHFDYVDPHYLYPPGG MAV_3565|M.avium_104 HRSIVVTTNGNITDDFKPVYRAVLNFRRGWDIYNEHFDYVDPHYLYPPGG **: *: * ***** ***.*.: * :* :*.:****::***** Mflv_3915|M.gilvum_PYR-GCK TLIIAPFGYLPEVASRNWFIFFNTVAIILAGYFLLRLFNYTLSSVAAPAL Mvan_2488|M.vanbaalenii_PYR-1 TLIIAPFGYLPEVASRNWFIFFNTVAIVLAGYFLLRLFNFTLASVAAPAL TH_0624|M.thermoresistible__bu TLLMAPFGYLTPDVSRGWFIFFNTVAIVLAAYFLLRLFNFTLASVAAPAL MAB_2978|M.abscessus_ATCC_1997 TLLLAPFGYLPVDASRYWFITINTIAIVIAAYFLLRLFNFTLASVAAPAL MSMEG_2785|M.smegmatis_MC2_155 TLLLAPFGYLPVDASRYWYISFNVLAFLIAAYLMLRIFDYTLSSVAAPAL Rv2673|M.tuberculosis_H37Rv TLLMAPFGYLPFAPSRYLFISINTAAILVAAYLLLRMFNFTLTSVAAPAL Mb2692|M.bovis_AF2122/97 TLLMAPFGYLPFAPSRYLFISINTAAILVAAYLLLRMFNFTLTSVAAPAL MMAR_2043|M.marinum_M TLLMAPFGYLPFAPSRYLFISINTAAILLAAYLLLRLFNFTLTSVAAPAL MUL_3307|M.ulcerans_Agy99 TLLMAPFGYLPFAPSRYLFISINTAAILLAAYLLLRLFNFTLTSVAAPAL MLBr_01338|M.leprae_Br4923 TLLMAPFGYLPFAPSRYLFILINTGAILIAWYLILRLFKYTLSSVAAPTL MAV_3565|M.avium_104 TLLMAPFGYLPEYPSRYLFILINTVAILIAWYLLLRLFGYTLSSVAAPAL **::******. ** :* :*. *:::* *::**:* :**:*****:* Mflv_3915|M.gilvum_PYR-GCK LLAMFCTESVTNTLVFGNINGVLLLLEVLFFRWLLDG----NRNHEWLAG Mvan_2488|M.vanbaalenii_PYR-1 LLAMFCTESVTNTLVFGNINGVILLLEVLFFRWLLDG----NRSHEWWAG TH_0624|M.thermoresistible__bu LLAMFCTETVTNTLVFTNINGILLLLEVLFLRWLLDG----EKRHEWLAG MAB_2978|M.abscessus_ATCC_1997 LLAMFCTESVTNTLVFTNINGVVLLLEVLFFRWLLHG----TKKSEWLAG MSMEG_2785|M.smegmatis_MC2_155 VLAMFCTESVTNTLVFTNINGCMLLGAVLFFRWLLKG----GRNAELLAG Rv2673|M.tuberculosis_H37Rv ILAMFATETVTNTLVFTNINGCILLLEVLFLRWLLDG----RASRQWCGG Mb2692|M.bovis_AF2122/97 ILAMFATETVTNTLVFTNINGCILLLEVLFLRWLLDG----RASRQWCGG MMAR_2043|M.marinum_M VLAMFATETVTNTLVFTNINGCILLLEVLFLRWLLDG----RVSHQWWAG MUL_3307|M.ulcerans_Agy99 VLAMFTTETVTNTLVFTNINGCILLLEVLFLRWLLDG----RVSHQWWAG MLBr_01338|M.leprae_Br4923 LLAMFCTETVTSTLVFTNINGCIMLLEVLFLWWLINGSEPKTVSQQWWAG MAV_3565|M.avium_104 LLAMFCTETVTNTLVFTNINGCVLLAEMLFLRWLLDG----RVGRQWWAG :**** **:**.**** **** ::* :**: **:.* : .* Mflv_3915|M.gilvum_PYR-GCK ISIGLTLVVKPLLAPLLLLPLLNRQWRALVAAFVVPLVFNAAAWP----- Mvan_2488|M.vanbaalenii_PYR-1 VSIGLTLVVKPLLAPLLLLPLLNRQWRALVTAFAVPVAFNLAAWP----- TH_0624|M.thermoresistible__bu VSIGLTLVVKPLLAPLLLLPVLNRQWRALVTAFAVPLAFNAAAWP----- MAB_2978|M.abscessus_ATCC_1997 VAIGLTLVIKPLLAPLLLLPLLNRQWRVFAAAFGIPAFFNLVALYGPRKV MSMEG_2785|M.smegmatis_MC2_155 AAIGLTLVVKPSLAPLLLLPVLNRQFYTLITAFGVPLVFNIAAWP----- Rv2673|M.tuberculosis_H37Rv LAIGLTLVLKPLLGPLLLLPLLNRQWRALVAAVVVPVVVNVAALP----- Mb2692|M.bovis_AF2122/97 LAIGLTLVLKPLLGPLLLLPLLNRQWRALVAAVVVPVVVNVAALP----- MMAR_2043|M.marinum_M IAIGFTLVLKPLLGPLLLLPLLNRQWRTLVTAIVIPIVINLAALP----- MUL_3307|M.ulcerans_Agy99 IAIGFTLVLKPLLGPLLLLPLLNRQWRTLVTAIVIPIVINLAALP----- MLBr_01338|M.leprae_Br4923 GAIGLTLVLKPLLGPLLCLPLLNRQWQALVPAIALPVVINLAALP----- MAV_3565|M.avium_104 VAIGLTLTLKPVLGPLLLLPLLNRQWRALVPAFAIPILINAAAWP----- :**:**.:** *.*** **:****: .: .*. :* .* .* Mflv_3915|M.gilvum_PYR-GCK LISDPMNFVTRTVPYILSTRDYFNSSILGNGLYYGLPMWLIMTLRVTIIV Mvan_2488|M.vanbaalenii_PYR-1 LISDPMNFVTRTVPYIFSTRDYFNSSILGNGLYYGLPMWLIMSLRIAFVV TH_0624|M.thermoresistible__bu LVADPMNFVTRTVPYILSTRDYFNSSILGNGVYYGLPTWLIILLRIGFGL MAB_2978|M.abscessus_ATCC_1997 RIVDGWDYLRRTVKYLGETRDYFNSSIAGNGLYYGLPEPLIAFLRIAFLA MSMEG_2785|M.smegmatis_MC2_155 LVPDPMNFVRHTVPYIMSTRDYFNSSIVGNGIYYGLPMWLILLLRVVFLL Rv2673|M.tuberculosis_H37Rv LVSDPMSFFTRTLPYILGTRDYFNSSILGNGVYFGLPTWLILFLRILFTA Mb2692|M.bovis_AF2122/97 LVSDPMSFFTRTLPYILGTRDYFNSSILGNGVYFGLPTWLILFLRILFTA MMAR_2043|M.marinum_M LINHPMDFFTRTLPYILGTRDYFNSSIQGNGIYFGLPTWLILFLRLLFTA MUL_3307|M.ulcerans_Agy99 LINHPMDFFTRTLPYILGTRDYFNSSIQGNGIYFGLPTWLILFLRLLFTA MLBr_01338|M.leprae_Br4923 LVSHPMDFFTRTVPYILGTRDYFNSSIEGNGVYFGLPTWLIVFLRLLFTV MAV_3565|M.avium_104 LVSDPMDFVTRTLPYIGGVRDYFNSSIEGNGVYFGLPTWLIVFMRILFTL : . .:. :*: *: .******** ***:*:*** ** :*: : Mflv_3915|M.gilvum_PYR-GCK LGAISLWLLYRHYRTRDPFFWMLTSSGVLLTTSWLALSLGQGYYSIALFP Mvan_2488|M.vanbaalenii_PYR-1 LGAAALWLLYRYYRTRDPFFWMLTSSGVVLVTSWLVLSLGQGYYSIVLFP TH_0624|M.thermoresistible__bu LAVVALVLLYRYYRTRDPLLWMTTSAGVLLIASWLVLSLGQGYYSMMLFP MAB_2978|M.abscessus_ATCC_1997 IALVSVWLLYKYYRRRDPRFWALTTGGVLLTASFLLLGLGQGYYSMALFP MSMEG_2785|M.smegmatis_MC2_155 LAVGSLWLLYRYYRERDPRFWLLTSSGVLLTASFLLLSLGQGYYSTMLFP Rv2673|M.tuberculosis_H37Rv ITFGALWLLYRYYRTGDPLFWFTTSSGVLLLWSWLVMSLAQGYYSMMLFP Mb2692|M.bovis_AF2122/97 ITFGALWLLYRYYRTGDPLFWFTTSSGVLLLWSWLVMSLAQGYYSMMLFP MMAR_2043|M.marinum_M IAIASLWLLYRYYRTRDPLFWFTTSSGVLLLWSWLAMSLAQGYYSMMLFP MUL_3307|M.ulcerans_Agy99 IAIASLWLLYRYYRTRDPLFWFTTSSGVLLLWSWLAMSLAQGYYSMMLFP MLBr_01338|M.leprae_Br4923 LAICSLWLLNRYYRTRDPLFWFTCSTGVLLLWSWLVLPLAQGYYSMMLFP MAV_3565|M.avium_104 IAIGALWLLYRYYRTRDPRFWFTNSAGVLLLWSWLVLPLAQGYYSMMLFP : :: ** ::** ** :* : **:* *:* : *.***** *** Mflv_3915|M.gilvum_PYR-GCK FLMTVVLPNSVIRSWVAWLAAYGFLTMDRWLLWQ---LPSTGRAFEYLKI Mvan_2488|M.vanbaalenii_PYR-1 FLMTVVLPNSVIRNWVAWLAAYGFLTMDRWLLWQ---LPTTGRALEYLKI TH_0624|M.thermoresistible__bu FLMTVVLPNSVIRNWVAWLAVYGFMTMDRWLIVRPVEMLTTGRFLEYMKI MAB_2978|M.abscessus_ATCC_1997 FVMTIVLPNSVLRNWPAWLAVYGFFSMDRWLLGH---WPTTGRALEYLKI MSMEG_2785|M.smegmatis_MC2_155 FLMTVVLPNSVLRNWPAWLAIYGFMTMDRWLLGH---WPTTGRFLEYMKI Rv2673|M.tuberculosis_H37Rv FLMTVVLPNSVIRNWPAWLGVYGFMTLDRWLLFN---WMRWGRALEYLKI Mb2692|M.bovis_AF2122/97 FLMTVVLPNSVIRNWPAWLGVYGFMTLDRWLLFN---WMRWGRALEYLKI MMAR_2043|M.marinum_M FLMTITLRNSVIRNWPAWLGIYGFMTLDRWLLFN---WMRWGRALEYLKI MUL_3307|M.ulcerans_Agy99 FLMTITLRNSVIRNWPAWMGIYGFMTLDRWLLFN---WMRWGRALEYLKI MLBr_01338|M.leprae_Br4923 FLMTVVLPNSLIRNWPAWLGIYGFLTLDRWLLFN---WMRYGRALEYLKI MAV_3565|M.avium_104 FLMTVVLPNSLIRNWPAWLGIYGFMTLDRWLLFN---WMRYGRALEYLKI *:**:.* **::*.* **:. ***:::****: . ** :**:** Mflv_3915|M.gilvum_PYR-GCK TYGWSLMMVVVFAVLLFRYLDARQDNRLDEGIDPAWMK----QLTPAAKP Mvan_2488|M.vanbaalenii_PYR-1 TFGWSLMSVVVFSVLLFRYLDAKDDGRLDEGIDPPWMK----QLTPADKA TH_0624|M.thermoresistible__bu TYGWSLMLIVVTTVLYFRYLDAKADGRLDEGIDPPWLQKSKAEPVPATTS MAB_2978|M.abscessus_ATCC_1997 TYGWCLLLIVVMMVLVLRYRDARAAGTLDQGLDPEWMRAQTGTKESATDD MSMEG_2785|M.smegmatis_MC2_155 TYGWSLMLVVVFCVLYFRYLDAKQDGRLDQGIDPPWMAR---ERTPAPV- Rv2673|M.tuberculosis_H37Rv TYGWSLLLIVTFTVLYFRYLDAKADNRLDGGIDPAWLTP---EREGQR-- Mb2692|M.bovis_AF2122/97 TYGWSLLLIVTFTVLYFRYLDAKADNRLDGGIDPAWLTP---EREGQR-- MMAR_2043|M.marinum_M TYGWSLLLIVTFTVLYFRYLDAKAEDRLDSGIDPAWLTA---ERERASVD MUL_3307|M.ulcerans_Agy99 TYGWSLLLIVTFTVLYFRYLDAKAEDRLDSGIDPAWLTA---ERERASVD MLBr_01338|M.leprae_Br4923 TYGWSLLLIVVSTVLCFRYLDAKAENRLDHGIDPAWLTA---ERERASVN MAV_3565|M.avium_104 TYGWSLLLIVVFSVLCYRYLDAKAEDRLDRGIDPAWLTA---GRE----- *:**.*: :*. ** ** **: . ** *:** *: Mflv_3915|M.gilvum_PYR-GCK SE------------------ Mvan_2488|M.vanbaalenii_PYR-1 AE------------------ TH_0624|M.thermoresistible__bu ASGS---------------- MAB_2978|M.abscessus_ATCC_1997 DIERPEGESDRRAVAGATDS MSMEG_2785|M.smegmatis_MC2_155 -------------------- Rv2673|M.tuberculosis_H37Rv -------------------- Mb2692|M.bovis_AF2122/97 -------------------- MMAR_2043|M.marinum_M A------------------- MUL_3307|M.ulcerans_Agy99 A------------------- MLBr_01338|M.leprae_Br4923 A------------------- MAV_3565|M.avium_104 --------------------