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M. tuberculosis H37Rv Rv2673 (-)

annotation: POSSIBLE CONSERVED INTEGRAL MEMBRANE PROTEIN
coordinates: 2989291 - 2990592
length: 433

VYGALVTAADSIRTGLGASLLAGFRPRTGAPSTATILRSALWPAAVLSVLHRSIVLTTNGNITDDFKPVY
RAVLNFRRGWDIYNEHFDYVDPHYLYPPGGTLLMAPFGYLPFAPSRYLFISINTAAILVAAYLLLRMFNF
TLTSVAAPALILAMFATETVTNTLVFTNINGCILLLEVLFLRWLLDGRASRQWCGGLAIGLTLVLKPLLG
PLLLLPLLNRQWRALVAAVVVPVVVNVAALPLVSDPMSFFTRTLPYILGTRDYFNSSILGNGVYFGLPTW
LILFLRILFTAITFGALWLLYRYYRTGDPLFWFTTSSGVLLLWSWLVMSLAQGYYSMMLFPFLMTVVLPN
SVIRNWPAWLGVYGFMTLDRWLLFNWMRWGRALEYLKITYGWSLLLIVTFTVLYFRYLDAKADNRLDGGI
DPAWLTPEREGQR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2673--100% (433)POSSIBLE CONSERVED INTEGRAL MEMBRANE PROTEIN
M. tuberculosis H37RvRv2181-1e-0622.87% (341) integral membrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2692-0.0100.00% (433) integral membrane protein
M. gilvum PYR-GCKMflv_3915-1e-17570.94% (406) putative integral membrane protein
M. leprae Br4923MLBr_01338-0.082.26% (434) hypothetical protein MLBr_01338
M. abscessus ATCC 19977MAB_2978-1e-15663.29% (425) hypothetical protein MAB_2978
M. marinum MMMAR_2043-0.088.14% (430) transmembrane protein
M. avium 104MAV_3565-0.082.56% (430) hypothetical protein MAV_3565
M. smegmatis MC2 155MSMEG_2785-1e-17869.93% (429) putative integral membrane protein
M. thermoresistible (build 8)TH_0624-1e-16672.26% (393) POSSIBLE CONSERVED INTEGRAL MEMBRANE PROTEIN
M. ulcerans Agy99MUL_3307-0.087.67% (430) transmembrane protein
M. vanbaalenii PYR-1Mvan_2488-1e-17471.18% (406) putative integral membrane protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3915|M.gilvum_PYR-GCK          -----------MLTAFR--------PRTAPPTTATVLRSILWPLAIMAVI
Mvan_2488|M.vanbaalenii_PYR-1       -------MRDLVLTAFR--------PRTSPPTTASVLRSILWPLAIMAVI
TH_0624|M.thermoresistible__bu      -----------------------------------VLRSVLWPIAIMAVI
MAB_2978|M.abscessus_ATCC_1997      -----MVSVDALVTGFKN----SLAPKTAPPSVATILRSVLWPVAIMAVI
MSMEG_2785|M.smegmatis_MC2_155      MYCALVTATDSITTKLLN----AFRPRTSAPSTATVLRSVLWPIAILSVI
Rv2673|M.tuberculosis_H37Rv         MYGALVTAADSIRTGLGASLLAGFRPRTGAPSTATILRSALWPAAVLSVL
Mb2692|M.bovis_AF2122/97            MYGALVTAADSIRTGLGASLLAGFRPRTGAPSTATILRSALWPAAVLSVL
MMAR_2043|M.marinum_M               MYGALVTAADSTRTGLRECMQAAFRPRTGPPSASAILRSVLWPAAILSVL
MUL_3307|M.ulcerans_Agy99           MYGALVTAADSTRTGLRECMQAAFRPRTGPPSASAILRSVLWPAAILSVL
MLBr_01338|M.leprae_Br4923          MYGALVTAADSTQTGLRNWLLAVFHPRTHTPSTATIVRSALWPAAILSVL
MAV_3565|M.avium_104                MYGALVTAAES--TGLRDWIQAAFRPRTSAPSVATVLRSALWPIAIFSVL
                                                                       ::** *** *:::*:

Mflv_3915|M.gilvum_PYR-GCK          HRSYVLVFNRYITDDFAPVYRAVINFKFGWDIYNEHFDHVDPHYLYPPGG
Mvan_2488|M.vanbaalenii_PYR-1       HRSYVLVFNRYITDDFAPVYRAVINFKFGWDIYNENFGHVDPHYLYPPGG
TH_0624|M.thermoresistible__bu      HRSWVLSTNRSITDDFTPVYNAAVAFLRGQPVYTANFNHVDPHFLYPPGG
MAB_2978|M.abscessus_ATCC_1997      HRSYVLGTNGYITDDFGPVYRAVIAFKLHQPVYGENFNYVDPHYIYPPGG
MSMEG_2785|M.smegmatis_MC2_155      HRSYVLGTNGYITDDFGPVYRAVINFKLGLDIYNEQFDHVDPHYLYPPGG
Rv2673|M.tuberculosis_H37Rv         HRSIVLTTNGNITDDFKPVYRAVLNFRRGWDIYNEHFDYVDPHYLYPPGG
Mb2692|M.bovis_AF2122/97            HRSIVLTTNGNITDDFKPVYRAVLNFRRGWDIYNEHFDYVDPHYLYPPGG
MMAR_2043|M.marinum_M               HRAIVLTTNGNITDDFKPVYRAVLNFRRGWDIYNEHFDYVDPHYLYPPGG
MUL_3307|M.ulcerans_Agy99           HRAIVLTTNGNITDDFKPVYRAVLNFRRGWDIYNEHFDYVDPHYLYPPGG
MLBr_01338|M.leprae_Br4923          HRSTVITTNGNITDDFKPVYRAVLNFRHGWDIYNEHFDYVDPHYLYPPGG
MAV_3565|M.avium_104                HRSIVVTTNGNITDDFKPVYRAVLNFRRGWDIYNEHFDYVDPHYLYPPGG
                                    **: *:  *  ***** ***.*.: *     :*  :*.:****::*****

Mflv_3915|M.gilvum_PYR-GCK          TLIIAPFGYLPEVASRNWFIFFNTVAIILAGYFLLRLFNYTLSSVAAPAL
Mvan_2488|M.vanbaalenii_PYR-1       TLIIAPFGYLPEVASRNWFIFFNTVAIVLAGYFLLRLFNFTLASVAAPAL
TH_0624|M.thermoresistible__bu      TLLMAPFGYLTPDVSRGWFIFFNTVAIVLAAYFLLRLFNFTLASVAAPAL
MAB_2978|M.abscessus_ATCC_1997      TLLLAPFGYLPVDASRYWFITINTIAIVIAAYFLLRLFNFTLASVAAPAL
MSMEG_2785|M.smegmatis_MC2_155      TLLLAPFGYLPVDASRYWYISFNVLAFLIAAYLMLRIFDYTLSSVAAPAL
Rv2673|M.tuberculosis_H37Rv         TLLMAPFGYLPFAPSRYLFISINTAAILVAAYLLLRMFNFTLTSVAAPAL
Mb2692|M.bovis_AF2122/97            TLLMAPFGYLPFAPSRYLFISINTAAILVAAYLLLRMFNFTLTSVAAPAL
MMAR_2043|M.marinum_M               TLLMAPFGYLPFAPSRYLFISINTAAILLAAYLLLRLFNFTLTSVAAPAL
MUL_3307|M.ulcerans_Agy99           TLLMAPFGYLPFAPSRYLFISINTAAILLAAYLLLRLFNFTLTSVAAPAL
MLBr_01338|M.leprae_Br4923          TLLMAPFGYLPFAPSRYLFILINTGAILIAWYLILRLFKYTLSSVAAPTL
MAV_3565|M.avium_104                TLLMAPFGYLPEYPSRYLFILINTVAILIAWYLLLRLFGYTLSSVAAPAL
                                    **::******.   **  :* :*. *:::* *::**:* :**:*****:*

Mflv_3915|M.gilvum_PYR-GCK          LLAMFCTESVTNTLVFGNINGVLLLLEVLFFRWLLDG----NRNHEWLAG
Mvan_2488|M.vanbaalenii_PYR-1       LLAMFCTESVTNTLVFGNINGVILLLEVLFFRWLLDG----NRSHEWWAG
TH_0624|M.thermoresistible__bu      LLAMFCTETVTNTLVFTNINGILLLLEVLFLRWLLDG----EKRHEWLAG
MAB_2978|M.abscessus_ATCC_1997      LLAMFCTESVTNTLVFTNINGVVLLLEVLFFRWLLHG----TKKSEWLAG
MSMEG_2785|M.smegmatis_MC2_155      VLAMFCTESVTNTLVFTNINGCMLLGAVLFFRWLLKG----GRNAELLAG
Rv2673|M.tuberculosis_H37Rv         ILAMFATETVTNTLVFTNINGCILLLEVLFLRWLLDG----RASRQWCGG
Mb2692|M.bovis_AF2122/97            ILAMFATETVTNTLVFTNINGCILLLEVLFLRWLLDG----RASRQWCGG
MMAR_2043|M.marinum_M               VLAMFATETVTNTLVFTNINGCILLLEVLFLRWLLDG----RVSHQWWAG
MUL_3307|M.ulcerans_Agy99           VLAMFTTETVTNTLVFTNINGCILLLEVLFLRWLLDG----RVSHQWWAG
MLBr_01338|M.leprae_Br4923          LLAMFCTETVTSTLVFTNINGCIMLLEVLFLWWLINGSEPKTVSQQWWAG
MAV_3565|M.avium_104                LLAMFCTETVTNTLVFTNINGCVLLAEMLFLRWLLDG----RVGRQWWAG
                                    :**** **:**.**** **** ::*  :**: **:.*        :  .*

Mflv_3915|M.gilvum_PYR-GCK          ISIGLTLVVKPLLAPLLLLPLLNRQWRALVAAFVVPLVFNAAAWP-----
Mvan_2488|M.vanbaalenii_PYR-1       VSIGLTLVVKPLLAPLLLLPLLNRQWRALVTAFAVPVAFNLAAWP-----
TH_0624|M.thermoresistible__bu      VSIGLTLVVKPLLAPLLLLPVLNRQWRALVTAFAVPLAFNAAAWP-----
MAB_2978|M.abscessus_ATCC_1997      VAIGLTLVIKPLLAPLLLLPLLNRQWRVFAAAFGIPAFFNLVALYGPRKV
MSMEG_2785|M.smegmatis_MC2_155      AAIGLTLVVKPSLAPLLLLPVLNRQFYTLITAFGVPLVFNIAAWP-----
Rv2673|M.tuberculosis_H37Rv         LAIGLTLVLKPLLGPLLLLPLLNRQWRALVAAVVVPVVVNVAALP-----
Mb2692|M.bovis_AF2122/97            LAIGLTLVLKPLLGPLLLLPLLNRQWRALVAAVVVPVVVNVAALP-----
MMAR_2043|M.marinum_M               IAIGFTLVLKPLLGPLLLLPLLNRQWRTLVTAIVIPIVINLAALP-----
MUL_3307|M.ulcerans_Agy99           IAIGFTLVLKPLLGPLLLLPLLNRQWRTLVTAIVIPIVINLAALP-----
MLBr_01338|M.leprae_Br4923          GAIGLTLVLKPLLGPLLCLPLLNRQWQALVPAIALPVVINLAALP-----
MAV_3565|M.avium_104                VAIGLTLTLKPVLGPLLLLPLLNRQWRALVPAFAIPILINAAAWP-----
                                     :**:**.:** *.*** **:****: .: .*. :*  .* .*       

Mflv_3915|M.gilvum_PYR-GCK          LISDPMNFVTRTVPYILSTRDYFNSSILGNGLYYGLPMWLIMTLRVTIIV
Mvan_2488|M.vanbaalenii_PYR-1       LISDPMNFVTRTVPYIFSTRDYFNSSILGNGLYYGLPMWLIMSLRIAFVV
TH_0624|M.thermoresistible__bu      LVADPMNFVTRTVPYILSTRDYFNSSILGNGVYYGLPTWLIILLRIGFGL
MAB_2978|M.abscessus_ATCC_1997      RIVDGWDYLRRTVKYLGETRDYFNSSIAGNGLYYGLPEPLIAFLRIAFLA
MSMEG_2785|M.smegmatis_MC2_155      LVPDPMNFVRHTVPYIMSTRDYFNSSIVGNGIYYGLPMWLILLLRVVFLL
Rv2673|M.tuberculosis_H37Rv         LVSDPMSFFTRTLPYILGTRDYFNSSILGNGVYFGLPTWLILFLRILFTA
Mb2692|M.bovis_AF2122/97            LVSDPMSFFTRTLPYILGTRDYFNSSILGNGVYFGLPTWLILFLRILFTA
MMAR_2043|M.marinum_M               LINHPMDFFTRTLPYILGTRDYFNSSIQGNGIYFGLPTWLILFLRLLFTA
MUL_3307|M.ulcerans_Agy99           LINHPMDFFTRTLPYILGTRDYFNSSIQGNGIYFGLPTWLILFLRLLFTA
MLBr_01338|M.leprae_Br4923          LVSHPMDFFTRTVPYILGTRDYFNSSIEGNGVYFGLPTWLIVFLRLLFTV
MAV_3565|M.avium_104                LVSDPMDFVTRTLPYIGGVRDYFNSSIEGNGVYFGLPTWLIVFMRILFTL
                                     : .  .:. :*: *:  .******** ***:*:***  **  :*: :  

Mflv_3915|M.gilvum_PYR-GCK          LGAISLWLLYRHYRTRDPFFWMLTSSGVLLTTSWLALSLGQGYYSIALFP
Mvan_2488|M.vanbaalenii_PYR-1       LGAAALWLLYRYYRTRDPFFWMLTSSGVVLVTSWLVLSLGQGYYSIVLFP
TH_0624|M.thermoresistible__bu      LAVVALVLLYRYYRTRDPLLWMTTSAGVLLIASWLVLSLGQGYYSMMLFP
MAB_2978|M.abscessus_ATCC_1997      IALVSVWLLYKYYRRRDPRFWALTTGGVLLTASFLLLGLGQGYYSMALFP
MSMEG_2785|M.smegmatis_MC2_155      LAVGSLWLLYRYYRERDPRFWLLTSSGVLLTASFLLLSLGQGYYSTMLFP
Rv2673|M.tuberculosis_H37Rv         ITFGALWLLYRYYRTGDPLFWFTTSSGVLLLWSWLVMSLAQGYYSMMLFP
Mb2692|M.bovis_AF2122/97            ITFGALWLLYRYYRTGDPLFWFTTSSGVLLLWSWLVMSLAQGYYSMMLFP
MMAR_2043|M.marinum_M               IAIASLWLLYRYYRTRDPLFWFTTSSGVLLLWSWLAMSLAQGYYSMMLFP
MUL_3307|M.ulcerans_Agy99           IAIASLWLLYRYYRTRDPLFWFTTSSGVLLLWSWLAMSLAQGYYSMMLFP
MLBr_01338|M.leprae_Br4923          LAICSLWLLNRYYRTRDPLFWFTCSTGVLLLWSWLVLPLAQGYYSMMLFP
MAV_3565|M.avium_104                IAIGALWLLYRYYRTRDPRFWFTNSAGVLLLWSWLVLPLAQGYYSMMLFP
                                    :   :: ** ::**  ** :*   : **:*  *:* : *.*****  ***

Mflv_3915|M.gilvum_PYR-GCK          FLMTVVLPNSVIRSWVAWLAAYGFLTMDRWLLWQ---LPSTGRAFEYLKI
Mvan_2488|M.vanbaalenii_PYR-1       FLMTVVLPNSVIRNWVAWLAAYGFLTMDRWLLWQ---LPTTGRALEYLKI
TH_0624|M.thermoresistible__bu      FLMTVVLPNSVIRNWVAWLAVYGFMTMDRWLIVRPVEMLTTGRFLEYMKI
MAB_2978|M.abscessus_ATCC_1997      FVMTIVLPNSVLRNWPAWLAVYGFFSMDRWLLGH---WPTTGRALEYLKI
MSMEG_2785|M.smegmatis_MC2_155      FLMTVVLPNSVLRNWPAWLAIYGFMTMDRWLLGH---WPTTGRFLEYMKI
Rv2673|M.tuberculosis_H37Rv         FLMTVVLPNSVIRNWPAWLGVYGFMTLDRWLLFN---WMRWGRALEYLKI
Mb2692|M.bovis_AF2122/97            FLMTVVLPNSVIRNWPAWLGVYGFMTLDRWLLFN---WMRWGRALEYLKI
MMAR_2043|M.marinum_M               FLMTITLRNSVIRNWPAWLGIYGFMTLDRWLLFN---WMRWGRALEYLKI
MUL_3307|M.ulcerans_Agy99           FLMTITLRNSVIRNWPAWMGIYGFMTLDRWLLFN---WMRWGRALEYLKI
MLBr_01338|M.leprae_Br4923          FLMTVVLPNSLIRNWPAWLGIYGFLTLDRWLLFN---WMRYGRALEYLKI
MAV_3565|M.avium_104                FLMTVVLPNSLIRNWPAWLGIYGFMTLDRWLLFN---WMRYGRALEYLKI
                                    *:**:.* **::*.* **:. ***:::****: .       ** :**:**

Mflv_3915|M.gilvum_PYR-GCK          TYGWSLMMVVVFAVLLFRYLDARQDNRLDEGIDPAWMK----QLTPAAKP
Mvan_2488|M.vanbaalenii_PYR-1       TFGWSLMSVVVFSVLLFRYLDAKDDGRLDEGIDPPWMK----QLTPADKA
TH_0624|M.thermoresistible__bu      TYGWSLMLIVVTTVLYFRYLDAKADGRLDEGIDPPWLQKSKAEPVPATTS
MAB_2978|M.abscessus_ATCC_1997      TYGWCLLLIVVMMVLVLRYRDARAAGTLDQGLDPEWMRAQTGTKESATDD
MSMEG_2785|M.smegmatis_MC2_155      TYGWSLMLVVVFCVLYFRYLDAKQDGRLDQGIDPPWMAR---ERTPAPV-
Rv2673|M.tuberculosis_H37Rv         TYGWSLLLIVTFTVLYFRYLDAKADNRLDGGIDPAWLTP---EREGQR--
Mb2692|M.bovis_AF2122/97            TYGWSLLLIVTFTVLYFRYLDAKADNRLDGGIDPAWLTP---EREGQR--
MMAR_2043|M.marinum_M               TYGWSLLLIVTFTVLYFRYLDAKAEDRLDSGIDPAWLTA---ERERASVD
MUL_3307|M.ulcerans_Agy99           TYGWSLLLIVTFTVLYFRYLDAKAEDRLDSGIDPAWLTA---ERERASVD
MLBr_01338|M.leprae_Br4923          TYGWSLLLIVVSTVLCFRYLDAKAENRLDHGIDPAWLTA---ERERASVN
MAV_3565|M.avium_104                TYGWSLLLIVVFSVLCYRYLDAKAEDRLDRGIDPAWLTA---GRE-----
                                    *:**.*: :*.  **  ** **:  . ** *:** *:             

Mflv_3915|M.gilvum_PYR-GCK          SE------------------
Mvan_2488|M.vanbaalenii_PYR-1       AE------------------
TH_0624|M.thermoresistible__bu      ASGS----------------
MAB_2978|M.abscessus_ATCC_1997      DIERPEGESDRRAVAGATDS
MSMEG_2785|M.smegmatis_MC2_155      --------------------
Rv2673|M.tuberculosis_H37Rv         --------------------
Mb2692|M.bovis_AF2122/97            --------------------
MMAR_2043|M.marinum_M               A-------------------
MUL_3307|M.ulcerans_Agy99           A-------------------
MLBr_01338|M.leprae_Br4923          A-------------------
MAV_3565|M.avium_104                --------------------