For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTSSHLIDTEQLLADQLAQASPDLLRGLLSTFIAALMGAEADALCGAGYRERSDERSNQRNGYRHRDFDT RAATIDVAIPKLRQGSYFPDWLLQRRKRAERALTSVVATCYLLGVSTRRMERLVETLGVTKLSKSQVSIM AKELDEAVEAFRTRPLDAGPYTFLAADALVLKVREAGRVVGVHTLIATGVNAEGYREILGIQVTSAEDGA GWLAFFRDLVARGLSGVALVTSDAHAGLVAAIGATLPAAAWQRCRTHYAANHGRHNA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2666 | - | - | 100% (267) | truncated IS1081 transposase |
| M. tuberculosis H37Rv | Rv2512c | - | e-145 | 100.00% (261) | IS1081 transposase |
| M. tuberculosis H37Rv | Rv1199c | - | e-145 | 100.00% (261) | transposase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2685 | - | 1e-149 | 100.00% (267) | truncated IS1081 transposase |
| M. gilvum PYR-GCK | Mflv_2876 | - | 1e-121 | 81.99% (261) | transposase, mutator type |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_4291 | - | 1e-95 | 66.41% (262) | transposase, Mutator family protein |
| M. smegmatis MC2 155 | MSMEG_4154 | - | 3e-51 | 44.15% (265) | transposase, Mutator family protein |
| M. thermoresistible (build 8) | TH_2560 | - | 1e-118 | 79.69% (261) | PUTATIVE transposase, mutator type |
| M. ulcerans Agy99 | MUL_4531 | - | 3e-18 | 28.15% (238) | transposase for IS2606 |
| M. vanbaalenii PYR-1 | Mvan_0454 | - | 1e-120 | 80.84% (261) | transposase, mutator type |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2666|M.tuberculosis_H37Rv -----------------------------MTSSHLIDTEQLLADQLAQAS
Mb2685|M.bovis_AF2122/97 -----------------------------MTSSHLIDTEQLLADQLAQAS
TH_2560|M.thermoresistible__bu -----------------------------MTTAHNIDLPTVLAERLTTTH
Mvan_0454|M.vanbaalenii_PYR-1 -----------------------------MTAAHNIDLPAVLAERLTTAH
Mflv_2876|M.gilvum_PYR-GCK ------------MILRETVQSHSSKGIDAMTTAHNIDLPTVLAERLTTAH
MAV_4291|M.avium_104 ---MSVMDVKRPPRDPSSQPSTESSRSPTMTAPHIVDPAGLLGEALAEAS
MSMEG_4154|M.smegmatis_MC2_155 -----------------------------MTQDHSALLAQLDALKSADAG
MUL_4531|M.ulcerans_Agy99 MMTKTVVAVQPSQNHEDEAGAVAAIDVPSSRDVDELEVARELVRQAREAG
. :
Rv2666|M.tuberculosis_H37Rv P------DLLRGLLSTFIAALMGAEADALCGAGYRERS-DERSNQRNGYR
Mb2685|M.bovis_AF2122/97 P------DLLRGLLSTFIAALMGAEADALCGAGYRERS-DERSNQRNGYR
TH_2560|M.thermoresistible__bu P------DVLRELLATFIHTLMGAEADALCGAGYGERS-AERTNSRNGYR
Mvan_0454|M.vanbaalenii_PYR-1 P------DVLRELLATFIHTLMGAEADALCGAGYGERS-SERTNSRNGYR
Mflv_2876|M.gilvum_PYR-GCK P------DVLRELLATFIHTLMGAEADALCGAGYGERS-AERTNSRNGYR
MAV_4291|M.avium_104 P------DLMRSLLQTVINALLSADADAVVGAEWGQPT-PGRRAQRNGYR
MSMEG_4154|M.smegmatis_MC2_155 -------AVFAELIRAGLQALIEAEATEVIGAGRYQRT-DGRATHRNGHR
MUL_4531|M.ulcerans_Agy99 VGLTGPGGLLKAMTKTVIETALDEELSEHLGYDRHDRAGYGSGNSRNGTR
:: : : : : : : * : : *** *
Rv2666|M.tuberculosis_H37Rv HRDFDTRAA-TIDVAIPKLRQGSYFPDWLLQRRKRAERALTSVVATCYLL
Mb2685|M.bovis_AF2122/97 HRDFDTRAA-TIDVAIPKLRQGSYFPDWLLQRRKRAERALTSVVATCYLL
TH_2560|M.thermoresistible__bu HRRFDTRAG-SLDLAIPKLRHGSYFPDWLLERRKRAERALTTVVATCYLL
Mvan_0454|M.vanbaalenii_PYR-1 HRQFDTRAG-SLDLAIPKLRQGSYFPDWLLERRKRAERALTTVVATCYLL
Mflv_2876|M.gilvum_PYR-GCK HRQFDTRAG-TLDLAIPKLRQGSYFPDWLLERRKRAERALTTVVATCYLL
MAV_4291|M.avium_104 HRGLDTRVG-TIDVAVPKLRKGTYFPDWLLERRKRAESALITVVADCYLA
MSMEG_4154|M.smegmatis_MC2_155 PKTVSTTAG-DVEVQIPKLRAGSFFPS-LLERRRRIDRALHAVIMEAYVH
MUL_4531|M.ulcerans_Agy99 SKTVLTDACGSIEIDVPRDRAGTFEPK-IVEKRQRRLTDVDEVVLSLYAR
: . * . ::: :*: * *:: *. ::::*:* : *: *
Rv2666|M.tuberculosis_H37Rv GVSTRRMERLVETLGVTK-LSKSQVSIMAKELDEAVEAFRTRPLD-AGPY
Mb2685|M.bovis_AF2122/97 GVSTRRMERLVETLGVTK-LSKSQVSIMAKELDEAVEAFRTRPLD-AGPY
TH_2560|M.thermoresistible__bu GVSTRRMDKLVETLGITS-LSKSQVSVMATELDTAVEAFRTRPLD-AGPY
Mvan_0454|M.vanbaalenii_PYR-1 GVSTRRMDKLVETLGITS-LSKSQVSVMAKELDAAVEAFRTRPLD-AGPY
Mflv_2876|M.gilvum_PYR-GCK GVSTRRMDKLVETLGITS-LSKSQVSVMAKELDAAVEAFRTRPLD-AGPY
MAV_4291|M.avium_104 GVSTRRMDKLVKTLGIDS-LSKSQVSRMATDLDEHVEAFRHRPLDSAGPF
MSMEG_4154|M.smegmatis_MC2_155 GVSTRSVDDLVAALGVGSGVSKSEVSRICAGLDKEIDAFRTRSLN-HTSF
MUL_4531|M.ulcerans_Agy99 GLTTGEISAHFAHIYDAA-VSKDTVSRITDRVLEEITAWHTRPLE--RVY
*::* :. . : :**. ** : : : *:: *.*: :
Rv2666|M.tuberculosis_H37Rv TFLAADALVLKVREAGRVVGVHTLIATGVNAEGYREILGIQVT--SAEDG
Mb2685|M.bovis_AF2122/97 TFLAADALVLKVREAGRVVGVHTLIATGVNAEGYREILGIQVT--SAEDG
TH_2560|M.thermoresistible__bu TFVAADALVLKVREQGRVVNVHALIATGVNAEGYREILGVDVT--TAEDG
Mvan_0454|M.vanbaalenii_PYR-1 TFVAADALVLKVREQGRVVNVHALIAVGVNAEGYREILGIDVS--TAEDG
Mflv_2876|M.gilvum_PYR-GCK TFVAADALVLKVREAGRVVNVHALIAVGVNAEGYREILGIDVT--TAEDG
MAV_4291|M.avium_104 TFVAADALTMKVREGGRVVNGVVLLATGVNGDGHREVLGMRVV--TSETG
MSMEG_4154|M.smegmatis_MC2_155 PYVFCDATFCKVRIGAHVVSQALVVATGVSIDGTREVLGTAVG--DSESF
MUL_4531|M.ulcerans_Agy99 AAVFIDALHVKIRD-GQVGPRPVYAAVGVDLAGHRDVLGMWAGEGDGESA
. : ** *:* .:* *.**. * *::** . .*
Rv2666|M.tuberculosis_H37Rv AGWLAFFRDLVARGLSGVALVTSDAHAGLVAAIGATLPAAAWQRCRTHYA
Mb2685|M.bovis_AF2122/97 AGWLAFFRDLVARGLSGVALVTSDAHAGLVAAIGATLPAAAWQRCRTHYA
TH_2560|M.thermoresistible__bu AGWLAFWRSLTARGLSGVKLVTSDAHTGLVAAIGATLPGATWQRCRTHYT
Mvan_0454|M.vanbaalenii_PYR-1 AGWLTFWRSLTARGLSGVRLVTSDAHAGLVAAIGATLPGAAWQRCRTHYT
Mflv_2876|M.gilvum_PYR-GCK AGWLTFWRSLTARGLSGVKLVTSDAHAGLVAAIGATLPGAAWQRCRTHYT
MAV_4291|M.avium_104 PAWNEFFADLVARGLAGVRLVTSDAHAGLREAIAANLPGAAWQRCRTHYA
MSMEG_4154|M.smegmatis_MC2_155 EFWREFLASLKARGLSGVHLVISDAHAGLKAAVAQQFTGSSWQRCRVHFM
MUL_4531|M.ulcerans_Agy99 KYWLAVLTELKNRGVADIFFLVCDGLKGLPDSVSAVFPDTVVQTCIIHLI
* . .* **::.: :: .*. ** ::. :. : * * *
Rv2666|M.tuberculosis_H37Rv AN-----------------HGRHNA-------------------------
Mb2685|M.bovis_AF2122/97 AN-----------------HGRHNA-------------------------
TH_2560|M.thermoresistible__bu TNLMAVTPKSSWPWVRTLLHSVFDQPDAESVAAQYDRIIDALVDKLPKVA
Mvan_0454|M.vanbaalenii_PYR-1 TNLMAITPKSSWPWVRTLLHSVFDQPDAESVAAQYDRVIDALADKLPKVA
Mflv_2876|M.gilvum_PYR-GCK TNLMSVTPKSSWPWVRTLLHSVFDQPDAESVAAQYDRIIDALSDKLPNVA
MAV_4291|M.avium_104 ANLMSICPKSMWPAVKAMLHSVYDQPDAPAVAAQFDRLIDYVTDKLPAVA
MSMEG_4154|M.smegmatis_MC2_155 RNLHGVVAAKHAPAVTAAVKTIFAHTDPVDVAAQWDQVADTLAASFPKVA
MUL_4531|M.ulcerans_Agy99 RGTFRYAGRQHHTAIARALKPIYTAVNAAAAAEALDAFDTEWGHRYPAAI
. : .
Rv2666|M.tuberculosis_H37Rv --------------------------------------------------
Mb2685|M.bovis_AF2122/97 --------------------------------------------------
TH_2560|M.thermoresistible__bu DHLQAARPDLLAFTAFPKQIWRQIWSNNP---------------------
Mvan_0454|M.vanbaalenii_PYR-1 DHLEAARADLLAFTAFPKQIWRQIWSNNP---------------------
Mflv_2876|M.gilvum_PYR-GCK DHLEAARPDLLAFTAFPKQIWRQIWSNNPQERLNKEIRRRTDVVGIFPDR
MAV_4291|M.avium_104 DHLATAREDILAFTAFPKDVWSQIWSNNPAERLNKEIRRRTDAVGIFPNR
MSMEG_4154|M.smegmatis_MC2_155 AMMDEAKADVLAFTAFPRTHWQKIWSNNPIVICSAAVS------------
MUL_4531|M.ulcerans_Agy99 RLWRNAWNEFIPFLDYDTEIRKVICSTNAIEWLNARYRRAIRARGHFPTE
Rv2666|M.tuberculosis_H37Rv --------------------------------------------------
Mb2685|M.bovis_AF2122/97 --------------------------------------------------
TH_2560|M.thermoresistible__bu ---------------------------------RSVN-RPSHDTIMGAA-
Mvan_0454|M.vanbaalenii_PYR-1 ---------------------------------LSVN-RPSGDTVQAAA-
Mflv_2876|M.gilvum_PYR-GCK AALIRLVGAVLAEQHDEWAESRRYLGLDVLSKSRTVNDTPTEQEATPAAL
MAV_4291|M.avium_104 DAIVRLVGAVLAEQNDEWAEGRRYLGLDILTRCRLTTITDDNPDIGANDM
MSMEG_4154|M.smegmatis_MC2_155 -------VFYVDHEGSEWSVLRSGCGYLQPSMKQILEGRCACCEGGFTAL
MUL_4531|M.ulcerans_Agy99 QSALKCLYLVTRSLDPTGTGQKRWTMRWKPALNAFAITFADRMPGSETT-
Rv2666|M.tuberculosis_H37Rv -----
Mb2685|M.bovis_AF2122/97 -----
TH_2560|M.thermoresistible__bu -----
Mvan_0454|M.vanbaalenii_PYR-1 -----
Mflv_2876|M.gilvum_PYR-GCK PA---
MAV_4291|M.avium_104 PALTA
MSMEG_4154|M.smegmatis_MC2_155 VA---
MUL_4531|M.ulcerans_Agy99 -----