For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. tuberculosis H37Rv Rv1199c (-)

annotation: POSSIBLE TRANSPOSASE
coordinates: 1341358 - 1342605
length: 415

TSSHLIDTEQLLADQLAQASPDLLRGLLSTFIAALMGAEADALCGAGYRERSDERSNQRNGYRHRDFDTR
AATIDVAIPKLRQGSYFPDWLLQRRKRAERALTSVVATCYLLGVSTRRMERLVETLGVTKLSKSQVSIMA
KELDEAVEAFRTRPLDAGPYTFLAADALVLKVREAGRVVGVHTLIATGVNAEGYREILGIQVTSAEDGAG
WLAFFRDLVARGLSGVALVTSDAHAGLVAAIGATLPAAAWQRCRTHYAANLMAATPKPSWPWVRTLLHSI
YDQPDAESVVAQYDRVLDALTDKLPAVAEHLDTARTDLLAFTAFPKQIWRQIWSNNPQERLNREVRRRTD
VVGIFPDRASIIRLVGAVLAEQHDEWIEGRRYLGLEVLTRARAALTSTEEPAKQQTTNTPALTT*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1199c--100% (415)POSSIBLE TRANSPOSASE
M. tuberculosis H37RvRv2512c-0.0100.00% (415) IS1081 transposase
M. tuberculosis H37RvRv3115-0.099.76% (415) transposase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3142-0.0100.00% (415) transposase
M. gilvum PYR-GCKMflv_2876-0.079.90% (408) transposase, mutator type
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum M-----
M. avium 104MAV_4291-1e-15766.02% (415) transposase, Mutator family protein
M. smegmatis MC2 155MSMEG_4154-4e-6943.36% (339) transposase, Mutator family protein
M. thermoresistible (build 8)TH_2560-1e-16080.24% (339) PUTATIVE transposase, mutator type
M. ulcerans Agy99MUL_4029-6e-2426.09% (345) transposase for IS2606
M. vanbaalenii PYR-1Mvan_0454-1e-16181.66% (338) transposase, mutator type

CLUSTAL 2.0.9 multiple sequence alignment


Rv1199c|M.tuberculosis_H37Rv        -----------------------------MTSSHLIDTEQLLADQLAQAS
Mb3142|M.bovis_AF2122/97            -----------------------------MTSSHLIDTEQLLADQLAQAS
TH_2560|M.thermoresistible__bu      -----------------------------MTTAHNIDLPTVLAERLTTTH
Mvan_0454|M.vanbaalenii_PYR-1       -----------------------------MTAAHNIDLPAVLAERLTTAH
Mflv_2876|M.gilvum_PYR-GCK          ------------MILRETVQSHSSKGIDAMTTAHNIDLPTVLAERLTTAH
MAV_4291|M.avium_104                ---MSVMDVKRPPRDPSSQPSTESSRSPTMTAPHIVDPAGLLGEALAEAS
MSMEG_4154|M.smegmatis_MC2_155      -----------------------------MTQDHSALLAQLDALKSADAG
MUL_4029|M.ulcerans_Agy99           MMTKTVVVVQPSQNHEDEAGAVAAIDVPSSRDVDELEVARELVRQAREAG
                                                                     .              : 

Rv1199c|M.tuberculosis_H37Rv        P------DLLRGLLSTFIAALMGAEADALCGAGYRERS-DERSNQRNGYR
Mb3142|M.bovis_AF2122/97            P------DLLRGLLSTFIAALMGAEADALCGAGYRERS-DERSNQRNGYR
TH_2560|M.thermoresistible__bu      P------DVLRELLATFIHTLMGAEADALCGAGYGERS-AERTNSRNGYR
Mvan_0454|M.vanbaalenii_PYR-1       P------DVLRELLATFIHTLMGAEADALCGAGYGERS-SERTNSRNGYR
Mflv_2876|M.gilvum_PYR-GCK          P------DVLRELLATFIHTLMGAEADALCGAGYGERS-AERTNSRNGYR
MAV_4291|M.avium_104                P------DLMRSLLQTVINALLSADADAVVGAEWGQPT-PGRRAQRNGYR
MSMEG_4154|M.smegmatis_MC2_155      -------AVFAELIRAGLQALIEAEATEVIGAGRYQRT-DGRATHRNGHR
MUL_4029|M.ulcerans_Agy99           VGLTGPGGLLKAMTKTVIETALDEELSEHLGYDRHDRAGYGSGNSRNGTR
                                            ::  :  : : : :  :     *    : :       *** *

Rv1199c|M.tuberculosis_H37Rv        HRDFDTRAA-TIDVAIPKLRQGSYFPDWLLQRRKRAERALTSVVATCYLL
Mb3142|M.bovis_AF2122/97            HRDFDTRAA-TIDVAIPKLRQGSYFPDWLLQRRKRAERALTSVVATCYLL
TH_2560|M.thermoresistible__bu      HRRFDTRAG-SLDLAIPKLRHGSYFPDWLLERRKRAERALTTVVATCYLL
Mvan_0454|M.vanbaalenii_PYR-1       HRQFDTRAG-SLDLAIPKLRQGSYFPDWLLERRKRAERALTTVVATCYLL
Mflv_2876|M.gilvum_PYR-GCK          HRQFDTRAG-TLDLAIPKLRQGSYFPDWLLERRKRAERALTTVVATCYLL
MAV_4291|M.avium_104                HRGLDTRVG-TIDVAVPKLRKGTYFPDWLLERRKRAESALITVVADCYLA
MSMEG_4154|M.smegmatis_MC2_155      PKTVSTTAG-DVEVQIPKLRAGSFFPS-LLERRRRIDRALHAVIMEAYVH
MUL_4029|M.ulcerans_Agy99           SKTVLTDACGSIEIDVPRDRAGTFEPK-IVEKRQRRLTDVDEVVLSLYAR
                                     : . * .   ::: :*: * *:: *. ::::*:*    :  *:   *  

Rv1199c|M.tuberculosis_H37Rv        GVSTRRMERLVETLGVTK-LSKSQVSIMAKELDEAVEAFRTRPLD-AGPY
Mb3142|M.bovis_AF2122/97            GVSTRRMERLVETLGVTK-LSKSQVSIMAKELDEAVEAFRTRPLD-AGPY
TH_2560|M.thermoresistible__bu      GVSTRRMDKLVETLGITS-LSKSQVSVMATELDTAVEAFRTRPLD-AGPY
Mvan_0454|M.vanbaalenii_PYR-1       GVSTRRMDKLVETLGITS-LSKSQVSVMAKELDAAVEAFRTRPLD-AGPY
Mflv_2876|M.gilvum_PYR-GCK          GVSTRRMDKLVETLGITS-LSKSQVSVMAKELDAAVEAFRTRPLD-AGPY
MAV_4291|M.avium_104                GVSTRRMDKLVKTLGIDS-LSKSQVSRMATDLDEHVEAFRHRPLDSAGPF
MSMEG_4154|M.smegmatis_MC2_155      GVSTRSVDDLVAALGVGSGVSKSEVSRICAGLDKEIDAFRTRSLN-HTSF
MUL_4029|M.ulcerans_Agy99           GLTTGEISAHFAHIYDAA-VSKDTVSRITDRVLEEMTAWHTRPLE--RVY
                                    *::*  :.  .  :     :**. ** :   :   : *:: *.*:    :

Rv1199c|M.tuberculosis_H37Rv        TFLAADALVLKVREAGRVVGVHTLIATGVNAEGYREILGIQVT--SAEDG
Mb3142|M.bovis_AF2122/97            TFLAADALVLKVREAGRVVGVHTLIATGVNAEGYREILGIQVT--SAEDG
TH_2560|M.thermoresistible__bu      TFVAADALVLKVREQGRVVNVHALIATGVNAEGYREILGVDVT--TAEDG
Mvan_0454|M.vanbaalenii_PYR-1       TFVAADALVLKVREQGRVVNVHALIAVGVNAEGYREILGIDVS--TAEDG
Mflv_2876|M.gilvum_PYR-GCK          TFVAADALVLKVREAGRVVNVHALIAVGVNAEGYREILGIDVT--TAEDG
MAV_4291|M.avium_104                TFVAADALTMKVREGGRVVNGVVLLATGVNGDGHREVLGMRVV--TSETG
MSMEG_4154|M.smegmatis_MC2_155      PYVFCDATFCKVRIGAHVVSQALVVATGVSIDGTREVLGTAVG--DSESF
MUL_4029|M.ulcerans_Agy99           AAVFIDALHVKIRD-GQVGPRPVYAAVGVDLAGHRDVLGMWAGEGDGESA
                                    . :  **   *:*  .:*       *.**.  * *::**  .    .*  

Rv1199c|M.tuberculosis_H37Rv        AGWLAFFRDLVARGLSGVALVTSDAHAGLVAAIGATLPAAAWQRCRTHYA
Mb3142|M.bovis_AF2122/97            AGWLAFFRDLVARGLSGVALVTSDAHAGLVAAIGATLPAAAWQRCRTHYA
TH_2560|M.thermoresistible__bu      AGWLAFWRSLTARGLSGVKLVTSDAHTGLVAAIGATLPGATWQRCRTHYT
Mvan_0454|M.vanbaalenii_PYR-1       AGWLTFWRSLTARGLSGVRLVTSDAHAGLVAAIGATLPGAAWQRCRTHYT
Mflv_2876|M.gilvum_PYR-GCK          AGWLTFWRSLTARGLSGVKLVTSDAHAGLVAAIGATLPGAAWQRCRTHYT
MAV_4291|M.avium_104                PAWNEFFADLVARGLAGVRLVTSDAHAGLREAIAANLPGAAWQRCRTHYA
MSMEG_4154|M.smegmatis_MC2_155      EFWREFLASLKARGLSGVHLVISDAHAGLKAAVAQQFTGSSWQRCRVHFM
MUL_4029|M.ulcerans_Agy99           KYWLAVLTELKNRGVADIFFLVCDGLKGLPDSVSAVFPDTVVQTCIIHLI
                                      *  .  .*  **::.: :: .*.  **  ::.  :. :  * *  *  

Rv1199c|M.tuberculosis_H37Rv        ANLMAATPKPSWPWVRTLLHSIYDQPDAESVVAQYDRVLDALTDKLPAVA
Mb3142|M.bovis_AF2122/97            ANLMAATPKPSWPWVRTLLHSIYDQPDAESVVAQYDRVLDALTDKLPAVA
TH_2560|M.thermoresistible__bu      TNLMAVTPKSSWPWVRTLLHSVFDQPDAESVAAQYDRIIDALVDKLPKVA
Mvan_0454|M.vanbaalenii_PYR-1       TNLMAITPKSSWPWVRTLLHSVFDQPDAESVAAQYDRVIDALADKLPKVA
Mflv_2876|M.gilvum_PYR-GCK          TNLMSVTPKSSWPWVRTLLHSVFDQPDAESVAAQYDRIIDALSDKLPNVA
MAV_4291|M.avium_104                ANLMSICPKSMWPAVKAMLHSVYDQPDAPAVAAQFDRLIDYVTDKLPAVA
MSMEG_4154|M.smegmatis_MC2_155      RNLHGVVAAKHAPAVTAAVKTIFAHTDPVDVAAQWDQVADTLAASFPKVA
MUL_4029|M.ulcerans_Agy99           RGTLRYPGRQHHTAIARALKPIYTAVNAAAAAEALDAFDTEWGHRYPAAI
                                     .          . :   ::.::   :.  ..   * .        * . 

Rv1199c|M.tuberculosis_H37Rv        EHLDTARTDLLAFTAFPKQIWRQIWSNNPQERLNREVRRRTDVVGIFPDR
Mb3142|M.bovis_AF2122/97            EHLDTARTDLLAFTAFPKQIWRQIWSNNPQERLNREVRRRTDVVGIFPDR
TH_2560|M.thermoresistible__bu      DHLQAARPDLLAFTAFPKQIWRQIWSNNP---------------------
Mvan_0454|M.vanbaalenii_PYR-1       DHLEAARADLLAFTAFPKQIWRQIWSNNP---------------------
Mflv_2876|M.gilvum_PYR-GCK          DHLEAARPDLLAFTAFPKQIWRQIWSNNPQERLNKEIRRRTDVVGIFPDR
MAV_4291|M.avium_104                DHLATAREDILAFTAFPKDVWSQIWSNNPAERLNKEIRRRTDAVGIFPNR
MSMEG_4154|M.smegmatis_MC2_155      AMMDEAKADVLAFTAFPRTHWQKIWSNNP---------------------
MUL_4029|M.ulcerans_Agy99           RLWRTAWNEFIPFLDYDTEIRKVICSTNAIESLNARYRRAIRARGHFPTE
                                         *  :.:.*  :       * *.*.                     

Rv1199c|M.tuberculosis_H37Rv        ASIIRLVGAVLAEQHDEWIEGRRYLGLEVLTRARAALTSTEEPAKQQTTN
Mb3142|M.bovis_AF2122/97            ASIIRLVGAVLAEQHDEWIEGRRYLGLEVLTRARAALTSTEEPAKQQTTN
TH_2560|M.thermoresistible__bu      -------------------------------------RSVN-RPSHDTIM
Mvan_0454|M.vanbaalenii_PYR-1       -------------------------------------LSVN-RPSGDTVQ
Mflv_2876|M.gilvum_PYR-GCK          AALIRLVGAVLAEQHDEWAESRRYLGLDVLSKS----RTVNDTPTEQEAT
MAV_4291|M.avium_104                DAIVRLVGAVLAEQNDEWAEGRRYLGLDILTRCR-LTTITDDNPDIGAND
MSMEG_4154|M.smegmatis_MC2_155      --IVICSAAVSVFYVDHEGSEWSVLRSGCGYLQPSMKQILEGRCACCEGG
MUL_4029|M.ulcerans_Agy99           QSALKCLYLVTRSLDPTGTGQKRWTMRWKPALNAFAITFADRMPGSETT-
                                                                            :         

Rv1199c|M.tuberculosis_H37Rv        TPALTT
Mb3142|M.bovis_AF2122/97            TPALTT
TH_2560|M.thermoresistible__bu      GAA---
Mvan_0454|M.vanbaalenii_PYR-1       AAA---
Mflv_2876|M.gilvum_PYR-GCK          PAALPA
MAV_4291|M.avium_104                MPALTA
MSMEG_4154|M.smegmatis_MC2_155      FTALVA
MUL_4029|M.ulcerans_Agy99           ------