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MLFAALRDVQWRKRRLVIAIVSTGLVFAMTLVLTGLVNGFRVEAERTVDSMGVDAFVVKAGAAGPFLGST PFAQIDLPQVARAPGVLAAAPLATAPSTIRQGTSARNVTAFGAPEHGPGMPRVSDGRAPSTPDEVAVSST LGRNLGDDLQVGARTLRIVGIVPESTALAKIPNIFLTTEGLQQLAYNGQPTISSIGIDGMPRQLPDGYQT VNRADAVSDLMRPLKVAVDAITVVAVLLWIVAALIVGSVVYLSALERLRDFAVFKAIGVPTRSILAGLAL QAVVVALLAAVVGGILSLLLAPLFPMTVVVPLSAFVALPAIATVIGLLASVAGLRRVVAIDPALAFGGP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2563 | - | - | 100% (349) | PROBABLE GLUTAMINE-TRANSPORT TRANSMEMBRANE PROTEIN ABC TRANSPORTER |
| M. tuberculosis H37Rv | Rv0072 | - | e-152 | 76.22% (349) | glutamine-transport transmembrane protein ABC transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2592 | - | 0.0 | 100.00% (349) | glutamine-transport transmembrane protein ABC transporter |
| M. gilvum PYR-GCK | Mflv_4128 | - | 3e-05 | 26.17% (107) | hypothetical protein Mflv_4128 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4672c | - | 1e-19 | 23.06% (373) | ABC transporter permease |
| M. marinum M | MMAR_0215 | - | 1e-150 | 76.22% (349) | glutamine-transport transmembrane protein ABC transporter |
| M. avium 104 | MAV_4427 | - | 5e-06 | 22.66% (353) | efflux ABC transporter, permease protein |
| M. smegmatis MC2 155 | MSMEG_2523 | - | 7e-05 | 26.17% (107) | efflux ABC transporter, permease protein, putative |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1005 | - | 7e-10 | 22.31% (363) | hypothetical protein Mvan_1005 |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_4427|M.avium_104 -------MFSLRELAVHRRRTTASIAVMAVSATYLVAVFGIFGSITGSVS
Mvan_1005|M.vanbaalenii_PYR-1 MIGDRMRVLNARELRRHPGRTAMSLAVVAISATLLVAVFGITGSITGSSD
Mflv_4128|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2523|M.smegmatis_MC2_155 --------------------------------------------------
Rv2563|M.tuberculosis_H37Rv --------------------------------------------------
Mb2592|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0215|M.marinum_M --------------------------------------------------
MAB_4672c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4427|M.avium_104 RLADGIAGVAALEVSGITDAGFADSVLADVAAVPGVATAAPMIRTTAATP
Mvan_1005|M.vanbaalenii_PYR-1 RLAAGIGGNATLEVSGVTDTGFPESVRPDVAKVPGVAAAIPMLRTSIGPP
Mflv_4128|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2523|M.smegmatis_MC2_155 --------------------------------------------------
Rv2563|M.tuberculosis_H37Rv --------------------------------------------------
Mb2592|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0215|M.marinum_M --------------------------------------------------
MAB_4672c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4427|M.avium_104 SGPVLLLGVDARTAALGGALTDAVSRPVRELSASPDGVQVGPRAGYAKGQ
Mvan_1005|M.vanbaalenii_PYR-1 GERVVVLGVDDSIRAMLSDLQRAVQDQIGPLVTQPGMVAVGAGTGHAVDD
Mflv_4128|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2523|M.smegmatis_MC2_155 --------------------------------------------------
Rv2563|M.tuberculosis_H37Rv --------------------------------------------------
Mb2592|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0215|M.marinum_M --------------------------------------------------
MAB_4672c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4427|M.avium_104 AFQLGSAPVTVTEVLAGRQFAELNGGHYVLAPLALAQRVTARAGQLDSIL
Mvan_1005|M.vanbaalenii_PYR-1 VIALGTGEVRVAAVITGADAERINGGNFIVGPLPLMQRLMGRVGMIDSVL
Mflv_4128|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2523|M.smegmatis_MC2_155 --------------------------------------------------
Rv2563|M.tuberculosis_H37Rv --------------------------------------------------
Mb2592|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0215|M.marinum_M --------------------------------------------------
MAB_4672c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4427|M.avium_104 ITLTPGADPAAVRAAVGAAVGGRAIVAAPSSRAARAGDGVRLMNYMALLG
Mvan_1005|M.vanbaalenii_PYR-1 VVGRPGADPASVRTGVTEAVDGRAVVTDPMFRSAQSGGAVSIMSTLLLSA
Mflv_4128|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2523|M.smegmatis_MC2_155 --------------------------------------------------
Rv2563|M.tuberculosis_H37Rv --------------------------------------------------
Mb2592|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0215|M.marinum_M --------------------------------------------------
MAB_4672c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4427|M.avium_104 AAVALVVGAFLIYTTMTMAITQRRPVISMLRALGGRRRAVVGDLLAEAAV
Mvan_1005|M.vanbaalenii_PYR-1 ASCALVVAGFLIFNAMSMAITQRRPAISLLRALGAKRRQIVADLLAEAAA
Mflv_4128|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2523|M.smegmatis_MC2_155 --------------------------------------------------
Rv2563|M.tuberculosis_H37Rv ------------------------MLFAALRDVQWRKRRLVIAIVSTGLV
Mb2592|M.bovis_AF2122/97 ------------------------MLFAALRDVQWRKRRLVIAIVSTGLV
MMAR_0215|M.marinum_M ------------------------MLFAALRDMQWRKRRLVIAIISTGII
MAB_4672c|M.abscessus_ATCC_199 -------------------------MIVAVKNLVAERARFVLSVVGVAVA
MAV_4427|M.avium_104 LGLIGGALGCGAGILAGRMAIGRLPRAVTQGLEARVEYWLPGYAVPLALA
Mvan_1005|M.vanbaalenii_PYR-1 VGLVGGLLGAALGVLIGMRSIGALPAALLQGYETRTEYILPGYAIPVALA
Mflv_4128|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2523|M.smegmatis_MC2_155 --------------------------------------------------
Rv2563|M.tuberculosis_H37Rv FAMTLVLTG------------------LVNGFRVEAERTVDSMGVDAFVV
Mb2592|M.bovis_AF2122/97 FAMTLVLTG------------------LVNGFRVEAERTVDSMGVDAFVV
MMAR_0215|M.marinum_M FGMTLVMTG------------------LANGFRVEAQHTVDSLGVDVFVV
MAB_4672c|M.abscessus_ATCC_199 VILVLVMSG------------------IFVGTTNQVTTYIDHSKGAVWVV
MAV_4427|M.avium_104 ATALTAVAAAAMAARQVYKVSPVEALAPVGASAADAVPPWLRAASGVGAL
Mvan_1005|M.vanbaalenii_PYR-1 ACVVVSVAAAMLAARQVYKVAPVEALAPVGVSAADAVPRRARLVVGVVGV
Mflv_4128|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2523|M.smegmatis_MC2_155 --------------------------------------------------
Rv2563|M.tuberculosis_H37Rv KAGAAG--------------------------------------------
Mb2592|M.bovis_AF2122/97 KAGAAG--------------------------------------------
MMAR_0215|M.marinum_M KAGAAG--------------------------------------------
MAB_4672c|M.abscessus_ATCC_199 QPGVSQ--------------------------------------------
MAV_4427|M.avium_104 ALFAVAALAVP--AGAPTGVLLGAVLVAELTAGFALTVPIVTATSALSRV
Mvan_1005|M.vanbaalenii_PYR-1 GLVAVAALVASRDLGKVSVAAVGLAAAGDIALCFAFAGPLVAGAAAVARA
Mflv_4128|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2523|M.smegmatis_MC2_155 --------------------------------------------------
Rv2563|M.tuberculosis_H37Rv ----------------------------------PFLGSTPFAQIDLPQV
Mb2592|M.bovis_AF2122/97 ----------------------------------PFLGSTPFAQIDLPQV
MMAR_0215|M.marinum_M ----------------------------------PFLGSIPFPDVDVARV
MAB_4672c|M.abscessus_ATCC_199 ----------------------------------MFRAVSWLPAEGKDRL
MAV_4427|M.avium_104 FGSCGALAAATIRRAPRRVWAT--VMTVLIGVLTTVVITGTNADMIGSAR
Mvan_1005|M.vanbaalenii_PYR-1 FGAPGALAAATIERSPRRVWAT--LMTVLIAVSITVQSTGANANAIDSTN
Mflv_4128|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2523|M.smegmatis_MC2_155 --------------------------------------------------
Rv2563|M.tuberculosis_H37Rv ARAPGVLAAAPLATAPSTIRQG--TSARNVTAFGAPEHGPGMPRVSDGR-
Mb2592|M.bovis_AF2122/97 ARAPGVLAAAPLATAPSTIRQG--TSARNVTAFGAPEHGPGMPRVSDGR-
MMAR_0215|M.marinum_M AAEPGVVAAAPLASMGTIMKEG--KSTRNVTAFGAPEHGPGMPEVSDGR-
MAB_4672c|M.abscessus_ATCC_199 LKVPGVQSAEPILGLPSDFVHKGGHTAYFVVGYDTATGIGGPWSLAEGR-
MAV_4427|M.avium_104 AIFAPVAEADVWVSADPPDSFPTD-VLPQG----LSERLAALPGAARVTE
Mvan_1005|M.vanbaalenii_PYR-1 ASFASLGEAGLYVSVSGPGVYPTAPILPKD----AEASIASIPGVAEVVP
Mflv_4128|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2523|M.smegmatis_MC2_155 --------------------------------------------------
Rv2563|M.tuberculosis_H37Rv -------------APSTPDEVAVSSTLGRN----LGDDLQVGARTLRIVG
Mb2592|M.bovis_AF2122/97 -------------APSTPDEVAVSSTLGRN----LGDDLQVGARTLRIVG
MMAR_0215|M.marinum_M -------------APSKPDEVAVSSTLNRH----IDDTLQLGAHKLRIVG
MAB_4672c|M.abscessus_ATCC_199 -------------NVAGSGEVVLDRVLAKKNKIHLGDTVRLVDGDFTVVG
MAV_4427|M.avium_104 GACGFAVVAGTRVLLDGFAAGSRDALFRALDDRVRAEVLAGRGVVLTQNL
Mvan_1005|M.vanbaalenii_PYR-1 GQMAYATLAGQRIIMQGLARGSVAPPSQAMNDQVREQVLAGDGVVVSRDI
Mflv_4128|M.gilvum_PYR-GCK -----------MSTQKGLAYG-----WLAARRRVREMVLP----------
MSMEG_2523|M.smegmatis_MC2_155 ------------MIQKGLAYG-----WLSARRRIREMVLP----------
Rv2563|M.tuberculosis_H37Rv ------------IVPESTALAKIPNIFLTTEGLQQLAYNGQ---------
Mb2592|M.bovis_AF2122/97 ------------IVPESTALAKIPNIFLTTEGLQQLAYNGQ---------
MMAR_0215|M.marinum_M ------------IVPNSTALAKIPNIFLTTEGLQRVAYNGQ---------
MAB_4672c|M.abscessus_ATCC_199 -------------LSKQTAAVGNFYAFISLVDAAHLLRAGN---------
. * : :
MAV_4427|M.avium_104 GKALNVRAGDRLRLQTPHGPREAAVLAVVPFFSTVIGTVGMDLAQLRAWF
Mvan_1005|M.vanbaalenii_PYR-1 ARSLGIGVGDELTLPTPTGQRRVRVLEIVPFFSLLGGVVSMSLTLLREWY
Mflv_4128|M.gilvum_PYR-GCK ------------AITTATG-----AYLVVLVFGMSAGIR-----------
MSMEG_2523|M.smegmatis_MC2_155 ------------VVTTATG-----AFLVVLVFAMSAGIR-----------
Rv2563|M.tuberculosis_H37Rv ------------PTISSIG-----IDGMPRQLPDGYQTVN----------
Mb2592|M.bovis_AF2122/97 ------------PTISSIG-----IDGMPRQLPDGYQTVN----------
MMAR_0215|M.marinum_M ------------PMITSIG-----IDGSPRELPEGYQTYD----------
MAB_4672c|M.abscessus_ATCC_199 -------RVSYFLVQPTVGFTGDQVVDSVRKSVPGMDAFTS---------
.. *
MAV_4427|M.avium_104 DRPAATTLQITAAPGVDPRRLLADVRATVPAPNHVYDGRAALAGLQAPLH
Mvan_1005|M.vanbaalenii_PYR-1 ARPGSTVLAVNFTPGADRDQVAATIRGRVPADVLVYPGQEAAAAVGDSMA
Mflv_4128|M.gilvum_PYR-GCK -------------------------------------EQSESLGYADEIS
MSMEG_2523|M.smegmatis_MC2_155 -------------------------------------EQSAVIGHAEEIN
Rv2563|M.tuberculosis_H37Rv -------------------------------------RADAVSDLMRPLK
Mb2592|M.bovis_AF2122/97 -------------------------------------RADAVSDLMRPLK
MMAR_0215|M.marinum_M -------------------------------------REGAVNDLIRPLK
MAB_4672c|M.abscessus_ATCC_199 -------------------------------------ETFAENSRAIVIS
:
MAV_4427|M.avium_104 QSMFIANAVWIIVVAVAAVALLNTLTLSVTERRREIGVLRAMGAGRRFIL
Mvan_1005|M.vanbaalenii_PYR-1 QGTALIDIMAWIVVFVAGVALLNTLMLSVLERRRELGMLRAMGSSRRFAL
Mflv_4128|M.gilvum_PYR-GCK R---AVVLIAVTVLLVGVAEVAVVTTRTVAHRTRELGVLAANGVPRAPVV
MSMEG_2523|M.smegmatis_MC2_155 R---AVILIAVTVLLVGAVEVAVATTRTVAHRTRELGVLGANGIPRGPVV
Rv2563|M.tuberculosis_H37Rv VAVDAITVVAVLLWIVAALIVGSVVYLSALERLRDFAVFKAIGVPTRSIL
Mb2592|M.bovis_AF2122/97 VAVDAITVVAVLLWIVAALIVGSVVYLSALERLRDFAVFKAIGVPTRSIL
MMAR_0215|M.marinum_M VAVNSISIVAVLLWIVAVLIVGSVVYLSALERMRDFAVFKAIGTPTHSIM
MAB_4672c|M.abscessus_ATCC_199 MIGRPLRTMIGIAALVGVALVGLTVLAVTTEQMSDFGVLRALGVRPVQLC
: *. : . . .: ::.:: * *
MAV_4427|M.avium_104 RMVLAEAAGIGCVGGGLGFLLG-----LADQWLFSRISGDMMNFPVAFRL
Mvan_1005|M.vanbaalenii_PYR-1 RTVLAEAAGIGVVGAALGAVLG-----VVNQYLTAAALSNVLSIDVVYRP
Mflv_4128|M.gilvum_PYR-GCK AALLVEPLLAAVLGALAGVLLA-----VVTGIVLGIAGLVATGVSSAGLA
MSMEG_2523|M.smegmatis_MC2_155 AALLVEPLVAAVLGALAGAGAA-----SVTAALVALAGLAPTGVSVAGIL
Rv2563|M.tuberculosis_H37Rv AGLALQAVVVALLAAVVGGILS-----LLLAPLFPMTVVVPLSAFVALPA
Mb2592|M.bovis_AF2122/97 AGLALQAVVVALLAAVVGGILS-----LLLAPLFPMTVVVPLSAFVALPA
MMAR_0215|M.marinum_M AGLALQALVVSLLAAVVGVVLS-----KLLAPLFPMIVAVPGGAYLALPV
MAB_4672c|M.abscessus_ATCC_199 RTVIAQAALIAGLGYILGAGITYGVQFLVKDRLGDVTVEVTPAMLAGMAA
: :. . :. * :
MAV_4427|M.avium_104 SPLALACTAGALGITLLGSVPPARRAARLNIIEAVSVN
Mvan_1005|M.vanbaalenii_PYR-1 SPLAMLFACAAFGLTLLGAVPPAVRAARLDIVAAVAVD
Mflv_4128|M.gilvum_PYR-GCK AGSGIAVVVSVAAAVATSVVPTWKAASRPPVQSLASGA
MSMEG_2523|M.smegmatis_MC2_155 AGCLIAFGVSIVAAVATSFVPTWNAASRPPIRSLTAGG
Rv2563|M.tuberculosis_H37Rv IATVIGLLASVAGLRRVVAIDPALAFGGP---------
Mb2592|M.bovis_AF2122/97 IATVIGLLASVAGLRRVVAIDPALAFGGP---------
MMAR_0215|M.marinum_M VAILIGLLASVAGLKRVMTVDPALAFGGP---------
MAB_4672c|M.abscessus_ATCC_199 ATGVMAVIGSLIPVRRVTRIDPAQAFRR----------
: . : .