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MLFAALRDMQWRKRRLVITIISTGLIFGMTLVLTGLANGFRVEARHTVDSMGVDVFVVRSGAAGPFLGSI PFPDVDLARVAAEPGVMAAAPLGSVGTIMKEGTSTRNVTVFGAPEHGPGMPRVSEGRSPSKPDEVAASST MGRHLGDTVEVGARRLRVVGIVPNSTALAKIPNVFLTTEGLQKLAYNGQPNITSIGIIGMPRQLPEGYQT FDRVGAVNDLVRPLKVAVNSISIVAVLLWIVAVLIVGSVVYLSALERLRDFAVFKAIGTPTRSIMAGLAL QALVIALLAAVVGVVLAQVLAPLFPMIVAVPVGAYLALPVAAIVIGLFASVAGLKRVVTVDPAQAFGGP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0072 | - | - | 100% (349) | PROBABLE GLUTAMINE-TRANSPORT TRANSMEMBRANE PROTEIN ABC TRANSPORTER |
| M. tuberculosis H37Rv | Rv2563 | - | e-152 | 76.22% (349) | glutamine-transport transmembrane protein ABC transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0073 | - | 0.0 | 100.00% (349) | glutamine-transport transmembrane protein ABC transporter |
| M. gilvum PYR-GCK | Mflv_4128 | - | 5e-06 | 28.33% (120) | hypothetical protein Mflv_4128 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4672c | - | 2e-17 | 24.13% (373) | ABC transporter permease |
| M. marinum M | MMAR_0215 | - | 1e-170 | 85.67% (349) | glutamine-transport transmembrane protein ABC transporter |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_2523 | - | 4e-06 | 33.33% (102) | efflux ABC transporter, permease protein, putative |
| M. thermoresistible (build 8) | TH_3409 | - | 1e-06 | 23.18% (302) | PUTATIVE - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1005 | - | 5e-08 | 25.69% (362) | hypothetical protein Mvan_1005 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4128|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2523|M.smegmatis_MC2_155 --------------------------------------------------
Rv0072|M.tuberculosis_H37Rv --------------------------------------------------
Mb0073|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0215|M.marinum_M --------------------------------------------------
Mvan_1005|M.vanbaalenii_PYR-1 -----------MIGDRMRVLNARELRRHPGRTAMSLAVVAISATLLVAVF
TH_3409|M.thermoresistible__bu VTHTVTRRKLAAALSVFRIINLRAIRRHTLRALLAAISLGGGVAVVVAVM
MAB_4672c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_4128|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2523|M.smegmatis_MC2_155 --------------------------------------------------
Rv0072|M.tuberculosis_H37Rv --------------------------------------------------
Mb0073|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0215|M.marinum_M --------------------------------------------------
Mvan_1005|M.vanbaalenii_PYR-1 GITGSITGSSDRLAAGIGGNATLEVSGVTDTG-FPESVRPDVAKVPGVAA
TH_3409|M.thermoresistible__bu IETTSVSTAIDDVGYRIAGPAPLRIVGAANHGGIAPASIDAARSIPGVSA
MAB_4672c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_4128|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2523|M.smegmatis_MC2_155 --------------------------------------------------
Rv0072|M.tuberculosis_H37Rv --------------------------------------------------
Mb0073|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0215|M.marinum_M --------------------------------------------------
Mvan_1005|M.vanbaalenii_PYR-1 AIPMLRTSIGPPGERVVVLGVDDSIRAMLSDLQRAVQDQIGPLVTQPGMV
TH_3409|M.thermoresistible__bu VVPVIRAVTVVRTGDRETYVVALGIDCTARWIIDPAVCPPGQPEPPVPAT
MAB_4672c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_4128|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2523|M.smegmatis_MC2_155 --------------------------------------------------
Rv0072|M.tuberculosis_H37Rv --------------------------------------------------
Mb0073|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0215|M.marinum_M --------------------------------------------------
Mvan_1005|M.vanbaalenii_PYR-1 AVGAGTGHAVDDVIALGTGEVRVAAVITGADAERINGGNFIVGPLPLMQR
TH_3409|M.thermoresistible__bu SAILAGQLDPSSTVVTNAGQLVLTGVQQTDQLDTMNNGLVVALPLSVAKA
MAB_4672c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_4128|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2523|M.smegmatis_MC2_155 --------------------------------------------------
Rv0072|M.tuberculosis_H37Rv --------------------------------------------------
Mb0073|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0215|M.marinum_M --------------------------------------------------
Mvan_1005|M.vanbaalenii_PYR-1 LMGRVGMIDSVLVVGRPGADPASVRTGVTEAVDGRAVVTDPMFRSAQSGG
TH_3409|M.thermoresistible__bu EFARGDRVDLAYVTLADDAQAPRIQGQLRDVLG-PGYSVLTRADPDRGFN
MAB_4672c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_4128|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2523|M.smegmatis_MC2_155 --------------------------------------------------
Rv0072|M.tuberculosis_H37Rv --------------------------------------------------
Mb0073|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0215|M.marinum_M --------------------------------------------------
Mvan_1005|M.vanbaalenii_PYR-1 AVSIMSTLLLSAASCALVVAGFLIFNAMSMAITQRRPAISLLRALGAKRR
TH_3409|M.thermoresistible__bu VNSVLFPLLAIFALIAVGVGVILIAQITRLSVEERRHEVAVASALGASPQ
MAB_4672c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_4128|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2523|M.smegmatis_MC2_155 --------------------------------------------------
Rv0072|M.tuberculosis_H37Rv --------------------------------------------------
Mb0073|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0215|M.marinum_M --------------------------------------------------
Mvan_1005|M.vanbaalenii_PYR-1 QIVADLLAEAAAVGLVGGLLGAALGVLIGMRSIGALPAALLQGYETRTEY
TH_3409|M.thermoresistible__bu SAVTGFLAEAAVLGAVGSILGVLAGIGIAHPVVASASALTQLYVGVNVPV
MAB_4672c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_4128|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2523|M.smegmatis_MC2_155 --------------------------------------------------
Rv0072|M.tuberculosis_H37Rv --------------------------------------------------
Mb0073|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0215|M.marinum_M --------------------------------------------------
Mvan_1005|M.vanbaalenii_PYR-1 ILPGYAIPVALAACVVVSVAAAMLAARQVYKVAPVEALAPVGVSAADAVP
TH_3409|M.thermoresistible__bu VVEPAILVAGVGVGIVLAVLAALLPSLSAMNTAIAGELSGRSAQENTKPR
MAB_4672c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_4128|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2523|M.smegmatis_MC2_155 --------------------------------------------------
Rv0072|M.tuberculosis_H37Rv --------------------------------------------------
Mb0073|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0215|M.marinum_M --------------------------------------------------
Mvan_1005|M.vanbaalenii_PYR-1 RRARLVVGVVGVGLVAVAALVASRDLG--------KVSVAAVGLAAAGDI
TH_3409|M.thermoresistible__bu SIWPKALVLSTLGAAGVAAATLATRSGGLEPLQAVVSSAAVVIAIIGLLT
MAB_4672c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_4128|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2523|M.smegmatis_MC2_155 --------------------------------------------------
Rv0072|M.tuberculosis_H37Rv -----------------------MLFAALRDMQWRKRRLVITIISTGLIF
Mb0073|M.bovis_AF2122/97 -----------------------MLFAALRDMQWRKRRLVITIISTGLIF
MMAR_0215|M.marinum_M -----------------------MLFAALRDMQWRKRRLVIAIISTGIIF
Mvan_1005|M.vanbaalenii_PYR-1 ALCFAFAGPLVAGAAAVARAFGAPGALAAATIERSPRRVWATLMTVLIAV
TH_3409|M.thermoresistible__bu AAAYLSAQMITMVQLPADRAHGATTRVALTGLRANPTRTTAIAGAVAVPV
MAB_4672c|M.abscessus_ATCC_199 ------------------------MIVAVKNLVAERARFVLSVVGVAVAV
Mflv_4128|M.gilvum_PYR-GCK --MSTQKGLAYGWLAARRR-------------------------------
MSMEG_2523|M.smegmatis_MC2_155 ---MIQKGLAYGWLSARRR-------------------------------
Rv0072|M.tuberculosis_H37Rv GMTLVLTGLANGFRVEARHTVDSMGVDVFVVRSGAAGPFLGSIPFPDVDL
Mb0073|M.bovis_AF2122/97 GMTLVLTGLANGFRVEARHTVDSMGVDVFVVRSGAAGPFLGSIPFPDVDL
MMAR_0215|M.marinum_M GMTLVMTGLANGFRVEAQHTVDSLGVDVFVVKAGAAGPFLGSIPFPDVDV
Mvan_1005|M.vanbaalenii_PYR-1 SITVQSTGANANAIDSTNASFASLGEAGLYVSVSGPGVYPTAPILPKDAE
TH_3409|M.thermoresistible__bu AVAMLLSSFLTGINSASADLARAQATDRLVVGTTRFSDWGSLDAKASPET
MAB_4672c|M.abscessus_ATCC_199 ILVLVMSGIFVGTTNQVTTYIDHSKGAVWVVQPGVSQMFRAVSWLPAEGK
.. .
Mflv_4128|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_2523|M.smegmatis_MC2_155 --------------------------------------------------
Rv0072|M.tuberculosis_H37Rv ARVAAEPGVMAAAPLG--SVGTIMKEGTSTRNVTVFGAPEHGPGMPRVSE
Mb0073|M.bovis_AF2122/97 ARVAAEPGVMAAAPLG--SVGTIMKEGTSTRNVTVFGAPEHGPGMPRVSE
MMAR_0215|M.marinum_M ARVAAEPGVVAAAPLA--SMGTIMKEGKSTRNVTAFGAPEHGPGMPEVSD
Mvan_1005|M.vanbaalenii_PYR-1 ASIASIPGVAEVVPGQ--MAYATLAGQRIIMQGLARGSVAPPSQAMNDQV
TH_3409|M.thermoresistible__bu IAQLAALPGVERVERM--VEIEIALNDGSLAYVRAEDHPTFPFPVLAGED
MAB_4672c|M.abscessus_ATCC_199 DRLLKVPGVQSAEPILGLPSDFVHKGGHTAYFVVGYDTATGIGGPWSLAE
Mflv_4128|M.gilvum_PYR-GCK ------------------------------------VREMVLPAIT----
MSMEG_2523|M.smegmatis_MC2_155 ------------------------------------IREMVLPVVT----
Rv0072|M.tuberculosis_H37Rv GRSPSKPDEVAASSTMGRHLGDTV--------EVGARRLRVVGIVP----
Mb0073|M.bovis_AF2122/97 GRSPSKPDEVAASSTMGRHLGDTV--------EVGARRLRVVGIVP----
MMAR_0215|M.marinum_M GRAPSKPDEVAVSSTLNRHIDDTL--------QLGAHKLRIVGIVP----
Mvan_1005|M.vanbaalenii_PYR-1 REQVLAGDGVVVSRDIARSLGIGVGDELTLPTPTGQRRVRVLEIVPFFSL
TH_3409|M.thermoresistible__bu PEQTLAADQLIIGSVLAR-----------------EERLRVGDPVR----
MAB_4672c|M.abscessus_ATCC_199 GRNVAGSGEVVLDRVLAKKNKIHLG----DTVRLVDGDFTVVGLSK----
:
Mflv_4128|M.gilvum_PYR-GCK ----TATGAYLVVLVFGMSAGIREQSES----------------------
MSMEG_2523|M.smegmatis_MC2_155 ----TATGAFLVVLVFAMSAGIREQSAV----------------------
Rv0072|M.tuberculosis_H37Rv ----NSTALAKIPNVFLTTEGLQKLAYNGQPNITSIGIIGMPRQLPEGYQ
Mb0073|M.bovis_AF2122/97 ----NSTALAKIPNVFLTTEGLQKLAYNGQPNITSIGIIGMPRQLPEGYQ
MMAR_0215|M.marinum_M ----NSTALAKIPNIFLTTEGLQRVAYNGQPMITSIGIDGSPRELPEGYQ
Mvan_1005|M.vanbaalenii_PYR-1 LGGVVSMSLTLLREWYARPGSTVLAVNFTPGADRDQVAATIRGRVPADVL
TH_3409|M.thermoresistible__bu ----LGSGPEARDMTVGTIVATPEVGGR---------------------R
MAB_4672c|M.abscessus_ATCC_199 ---QTAAVGNFYAFISLVDAAHLLRAGNRVSYFLVQPTVGFTGDQVVDSV
. .
Mflv_4128|M.gilvum_PYR-GCK ----LGYADEISR-------AVVLIAV---------TVLLVGVAEVAVVT
MSMEG_2523|M.smegmatis_MC2_155 ----IGHAEEINR-------AVILIAV---------TVLLVGAVEVAVAT
Rv0072|M.tuberculosis_H37Rv TFDRVGAVNDLVRPLKVAVNSISIVAV---------LLWIVAVLIVGSVV
Mb0073|M.bovis_AF2122/97 TFDRVGAVNDLVRPLKVAVNSISIVAV---------LLWIVAVLIVGSVV
MMAR_0215|M.marinum_M TYDREGAVNDLIRPLKVAVNSISIVAV---------LLWIVAVLIVGSVV
Mvan_1005|M.vanbaalenii_PYR-1 VYPGQEAAAAVGDSMAQGTALIDIMAW---------IVVFVAGVALLNTL
TH_3409|M.thermoresistible__bu IYMPYRAAEEIFGPQAPGLVRIKPRDG---------VALDQIEADINATR
MAB_4672c|M.abscessus_ATCC_199 RKSVPGMDAFTSETFAENSRAIVISMIGRPLRTMIGIAALVGVALVGLTV
: : .
Mflv_4128|M.gilvum_PYR-GCK TRTVAHRTRELGVLAANG--VPRAPVVAALLVEPLLAAVLGALAGVLLAV
MSMEG_2523|M.smegmatis_MC2_155 TRTVAHRTRELGVLGANG--IPRGPVVAALLVEPLVAAVLGALAGAGAAS
Rv0072|M.tuberculosis_H37Rv YLSALERLRDFAVFKAIG--TPTRSIMAGLALQALVIALLAAVVGVVLAQ
Mb0073|M.bovis_AF2122/97 YLSALERLRDFAVFKAIG--TPTRSIMAGLALQALVIALLAAVVGVVLAQ
MMAR_0215|M.marinum_M YLSALERMRDFAVFKAIG--TPTHSIMAGLALQALVVSLLAAVVGVVLSK
Mvan_1005|M.vanbaalenii_PYR-1 MLSVLERRRELGMLRAMG--SSRRFALRTVLAEAAGIGVVGAALGAVLGV
TH_3409|M.thermoresistible__bu FNQPIKVVDAAGYEAATAGGVSRFLTTLNALKYGLLAIAFVSVTATLLLV
MAB_4672c|M.abscessus_ATCC_199 LAVTTEQMSDFGVLRALG--VRPVQLCRTVIAQAALIAGLGYILGAGITY
. . * . . ..
Mflv_4128|M.gilvum_PYR-GCK VTGIVL-----GIAGLVATGVSSAGLAAGSGIAVVVSVAAAVATSVVPTW
MSMEG_2523|M.smegmatis_MC2_155 VTAALV-----ALAGLAPTGVSVAGILAGCLIAFGVSIVAAVATSFVPTW
Rv0072|M.tuberculosis_H37Rv VLAPLF-----PMIVAVPVGAYLALPVAAIVIGLFASVAGLKRVVTVDPA
Mb0073|M.bovis_AF2122/97 VLAPLF-----PMIVAVPVGAYLALPVAAIVIGLFASVAGLKRVVTVDPA
MMAR_0215|M.marinum_M LLAPLF-----PMIVAVPGGAYLALPVVAILIGLLASVAGLKRVMTVDPA
Mvan_1005|M.vanbaalenii_PYR-1 VNQYLT-----AAALSNVLSIDVVYRPSPLAMLFACAAFGLTLLGAVPPA
TH_3409|M.thermoresistible__bu GMRRRR-----EMALLQALGATRGKVFAXXXLRRRRRGAPRPGVERRRRS
MAB_4672c|M.abscessus_ATCC_199 GVQFLVKDRLGDVTVEVTPAMLAGMAAATGVMAVIGSLIPVRRVTRIDPA
. :
Mflv_4128|M.gilvum_PYR-GCK KAASRPPVQSLASGA-
MSMEG_2523|M.smegmatis_MC2_155 NAASRPPIRSLTAGG-
Rv0072|M.tuberculosis_H37Rv QAFGGP----------
Mb0073|M.bovis_AF2122/97 QAFGGP----------
MMAR_0215|M.marinum_M LAFGGP----------
Mvan_1005|M.vanbaalenii_PYR-1 VRAARLDIVAAVAVD-
TH_3409|M.thermoresistible__bu RRRRPRPGRRPGAGPP
MAB_4672c|M.abscessus_ATCC_199 QAFRR-----------