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IVAVKNLVAERARFVLSVVGVAVAVILVLVMSGIFVGTTNQVTTYIDHSKGAVWVVQPGVSQMFRAVSWL PAEGKDRLLKVPGVQSAEPILGLPSDFVHKGGHTAYFVVGYDTATGIGGPWSLAEGRNVAGSGEVVLDRV LAKKNKIHLGDTVRLVDGDFTVVGLSKQTAAVGNFYAFISLVDAAHLLRAGNRVSYFLVQPTVGFTGDQV VDSVRKSVPGMDAFTSETFAENSRAIVISMIGRPLRTMIGIAALVGVALVGLTVLAVTTEQMSDFGVLRA LGVRPVQLCRTVIAQAALIAGLGYILGAGITYGVQFLVKDRLGDVTVEVTPAMLAGMAAATGVMAVIGSL IPVRRVTRIDPAQAFRR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4672c | - | - | 100% (368) | ABC transporter permease |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2592 | - | 1e-19 | 23.06% (373) | glutamine-transport transmembrane protein ABC transporter |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv2563 | - | 1e-19 | 23.06% (373) | glutamine-transport transmembrane protein ABC transporter |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0215 | - | 5e-14 | 20.38% (373) | glutamine-transport transmembrane protein ABC transporter |
| M. avium 104 | MAV_4427 | - | 2e-09 | 23.64% (385) | efflux ABC transporter, permease protein |
| M. smegmatis MC2 155 | MSMEG_2522 | - | 4e-10 | 23.48% (379) | efflux ABC transporter, permease protein |
| M. thermoresistible (build 8) | TH_3409 | - | 2e-05 | 28.89% (135) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0673 | - | 3e-08 | 24.19% (372) | ABC-type transporter |
| M. vanbaalenii PYR-1 | Mvan_1005 | - | 2e-08 | 26.53% (377) | hypothetical protein Mvan_1005 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2592|M.bovis_AF2122/97 --------------------------------------------------
Rv2563|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0215|M.marinum_M --------------------------------------------------
MAV_4427|M.avium_104 ------------------MFSLRELAVHRRRTTASIAVMAVSATYLVAVF
Mvan_1005|M.vanbaalenii_PYR-1 -----------MIGDRMRVLNARELRRHPGRTAMSLAVVAISATLLVAVF
MAB_4672c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3409|M.thermoresistible__bu VTHTVTRRKLAAALSVFRIINLRAIRRHTLRALLAAISLGGGVAVVVAVM
MUL_0673|M.ulcerans_Agy99 -------------MAIAVIVMLGVLLFIASYDSFRNLTASYNRTYDRLHF
MSMEG_2522|M.smegmatis_MC2_155 --------------------------------------------------
Mb2592|M.bovis_AF2122/97 --------------------------------------------------
Rv2563|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0215|M.marinum_M --------------------------------------------------
MAV_4427|M.avium_104 GIFGSITGSVSRLADGIAGVAALEVSGITDAG-FADSVLADVAAVPGVAT
Mvan_1005|M.vanbaalenii_PYR-1 GITGSITGSSDRLAAGIGGNATLEVSGVTDTG-FPESVRPDVAKVPGVAA
MAB_4672c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3409|M.thermoresistible__bu IETTSVSTAIDDVGYRIAGPAPLRIVGAANHGGIAPASIDAARSIPGVSA
MUL_0673|M.ulcerans_Agy99 ADLTASGGDPTQLAS-----AARELAGVENVATRVVRDRPVNIDGTQLIG
MSMEG_2522|M.smegmatis_MC2_155 --------------------------------------------------
Mb2592|M.bovis_AF2122/97 --------------------------------------------------
Rv2563|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0215|M.marinum_M --------------------------------------------------
MAV_4427|M.avium_104 AAPMIRTTAATPSGPVLLLGVDARTAALGGALTDAVSRPVRELSASPDGV
Mvan_1005|M.vanbaalenii_PYR-1 AIPMLRTSIGPPGERVVVLGVDDSIRAMLSDLQRAVQDQIGPLVTQPGMV
MAB_4672c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3409|M.thermoresistible__bu VVPVIRAVTVVRTGDRETYVVALGIDCTARWIIDPAVCPPGQPEPPVPAT
MUL_0673|M.ulcerans_Agy99 RVVGLTGGGHGVDDVEIVDGRAPDPDAPAQVAIEKHAAESFQLSPGDRVD
MSMEG_2522|M.smegmatis_MC2_155 --------------------------------------------------
Mb2592|M.bovis_AF2122/97 --------------------------------------------------
Rv2563|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0215|M.marinum_M --------------------------------------------------
MAV_4427|M.avium_104 QVGPRAGYAKGQAFQLGSAPVTVTEVLAGRQFAELNGGHYVLAPLALAQR
Mvan_1005|M.vanbaalenii_PYR-1 AVGAGTGHAVDDVIALGTGEVRVAAVITGADAERINGGNFIVGPLPLMQR
MAB_4672c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3409|M.thermoresistible__bu SAILAGQLDPSSTVVTNAGQLVLTGVQQTDQLDTMNNGLVVALPLSVAKA
MUL_0673|M.ulcerans_Agy99 VYNGSGWRTAEITGVARSPEYLWPARSRQDILPDPHSFAVLFAPPRLAAQ
MSMEG_2522|M.smegmatis_MC2_155 --------------------------------------------------
Mb2592|M.bovis_AF2122/97 --------------------------------------------------
Rv2563|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0215|M.marinum_M --------------------------------------------------
MAV_4427|M.avium_104 VTARAGQLDSILITLTPGADPAAVRAAVGAAVGGRAIVAAPSSRAARAGD
Mvan_1005|M.vanbaalenii_PYR-1 LMGRVGMIDSVLVVGRPGADPASVRTGVTEAVDGRAVVTDPMFRSAQSGG
MAB_4672c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3409|M.thermoresistible__bu EFARGDRVDLAYVTLADDAQAPRIQGQLRDVLG-PGYSVLTRADPDRGFN
MUL_0673|M.ulcerans_Agy99 LTGQPGP-NQTLVQMAAGATTADRDRVAGLLLSRGALDVQTRDEQPSNAA
MSMEG_2522|M.smegmatis_MC2_155 --------------------------------------------------
Mb2592|M.bovis_AF2122/97 --------------------------------------------------
Rv2563|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0215|M.marinum_M --------------------------------------------------
MAV_4427|M.avium_104 GVRLMN---YMALLGAAVALVVGAFLIYTTMTMAITQRRPVISMLRALGG
Mvan_1005|M.vanbaalenii_PYR-1 AVSIMS---TLLLSAASCALVVAGFLIFNAMSMAITQRRPAISLLRALGA
MAB_4672c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3409|M.thermoresistible__bu VNSVLF---PLLAIFALIAVGVGVILIAQITRLSVEERRHEVAVASALGA
MUL_0673|M.ulcerans_Agy99 LHEDLNGFSELAVGFPVLFLTAAAIAEYVVVTRVVQAERRIMGAMLAMGA
MSMEG_2522|M.smegmatis_MC2_155 --------------------------------------------------
Mb2592|M.bovis_AF2122/97 --------------------------------------------------
Rv2563|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0215|M.marinum_M --------------------------------------------------
MAV_4427|M.avium_104 RRRAVVGDLLAEAAVLGLIGGALGCGAGILAGRMAIGRLPRAVTQGLEAR
Mvan_1005|M.vanbaalenii_PYR-1 KRRQIVADLLAEAAAVGLVGGLLGAALGVLIGMRSIGALPAALLQGYETR
MAB_4672c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3409|M.thermoresistible__bu SPQSAVTGFLAEAAVLGAVGSILGVLAGIGIAHPVVASASALTQLYVGVN
MUL_0673|M.ulcerans_Agy99 RPATVIRHYLGYGVAVATMGALLGVVLGAGATSLVTGLYTAAIGVPDTVV
MSMEG_2522|M.smegmatis_MC2_155 --------------------------------------------------
Mb2592|M.bovis_AF2122/97 --------------------------------------------------
Rv2563|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0215|M.marinum_M --------------------------------------------------
MAV_4427|M.avium_104 VEYWLPGYAVPLALAATALTAVAAAAMAARQVYKVSPVEALAPVGASA--
Mvan_1005|M.vanbaalenii_PYR-1 TEYILPGYAIPVALAACVVVSVAAAMLAARQVYKVAPVEALAPVGVSA--
MAB_4672c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3409|M.thermoresistible__bu VPVVVEPAILVAGVGVGIVLAVLAALLPSLSAMNTAIAGELSGRSAQENT
MUL_0673|M.ulcerans_Agy99 RHHVS---TAVLGFALGLATGLVAVLVPAITAARTAPADAMRGQ------
MSMEG_2522|M.smegmatis_MC2_155 --------------------------METAESVSPSPTS-----------
Mb2592|M.bovis_AF2122/97 --------------------------------------------------
Rv2563|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0215|M.marinum_M --------------------------------------------------
MAV_4427|M.avium_104 ------ADAVPPWLRAASGVGALALFAVAALAVP--AGAPTGVLLGAVLV
Mvan_1005|M.vanbaalenii_PYR-1 ------ADAVPRRARLVVGVVGVGLVAVAALVASRDLGKVSVAAVGLAAA
MAB_4672c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3409|M.thermoresistible__bu KPRSIWPKALVLSTLGAAGVAAATLATRSGGLEPLQAVVSSAAVVIAIIG
MUL_0673|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_2522|M.smegmatis_MC2_155 --------------------------------------------------
Mb2592|M.bovis_AF2122/97 --------------------------MLFAALRDVQWRKRRLVIAIVSTG
Rv2563|M.tuberculosis_H37Rv --------------------------MLFAALRDVQWRKRRLVIAIVSTG
MMAR_0215|M.marinum_M --------------------------MLFAALRDMQWRKRRLVIAIISTG
MAV_4427|M.avium_104 AELTAGFALTVPIVTATSALSRVFGSCGALAAATIRRAPRRVWATVMTVL
Mvan_1005|M.vanbaalenii_PYR-1 GDIALCFAFAGPLVAGAAAVARAFGAPGALAAATIERSPRRVWATLMTVL
MAB_4672c|M.abscessus_ATCC_199 ---------------------------MIVAVKNLVAERARFVLSVVGVA
TH_3409|M.thermoresistible__bu LLTAAAYLSAQMITMVQLPADRAHGATTRVALTGLRANPTRTTAIAGAVA
MUL_0673|M.ulcerans_Agy99 -----RVLATAMGPLTRLTARWRLPAVIQLAVRSLTRSRGRTVATMVGGV
MSMEG_2522|M.smegmatis_MC2_155 --------TPPRSPQIATTTGNTFGCLVRFAFANIRRRPERFVLSVLGIA
* : *
Mb2592|M.bovis_AF2122/97 LVFAMTLVLTGLVNGFRVE-AERTVDSMGVDAFVVKAGAAGPFLGSTPFA
Rv2563|M.tuberculosis_H37Rv LVFAMTLVLTGLVNGFRVE-AERTVDSMGVDAFVVKAGAAGPFLGSTPFA
MMAR_0215|M.marinum_M IIFGMTLVMTGLANGFRVE-AQHTVDSLGVDVFVVKAGAAGPFLGSIPFP
MAV_4427|M.avium_104 IGVLTTVVITGTNADMIGS-ARAIFAPVAEADVWVSADPPDSFPTD-VLP
Mvan_1005|M.vanbaalenii_PYR-1 IAVSITVQSTGANANAIDS-TNASFASLGEAGLYVSVSGPGVYPTAPILP
MAB_4672c|M.abscessus_ATCC_199 VAVILVLVMSGIFVGTTNQ-VTTYIDHSKGAVWVVQPGVSQMFRAVSWLP
TH_3409|M.thermoresistible__bu VPVAVAMLLSSFLTGINSA-SADLARAQATDRLVVGTTRFSDWGSLDAKA
MUL_0673|M.ulcerans_Agy99 LALILVLASVGMMTSMRAM-LDVQFG-------EVQRQDASALVAPSAAG
MSMEG_2522|M.smegmatis_MC2_155 LAIACVTVVRTISSSFAITGADSVTDVLGDAQLWVVPAAGVHYDSEASAL
: . . . *
Mb2592|M.bovis_AF2122/97 QID-LPQVARAPGVLAAAP------LATAPSTIRQGTSARNVTAFGAPEH
Rv2563|M.tuberculosis_H37Rv QID-LPQVARAPGVLAAAP------LATAPSTIRQGTSARNVTAFGAPEH
MMAR_0215|M.marinum_M DVD-VARVAAEPGVVAAAP------LASMGTIMKEGKSTRNVTAFGAPEH
MAV_4427|M.avium_104 QGL-SERLAALPGAARVTEGACGFAVVAGTRVLLDGFAAGSRDALFRALD
Mvan_1005|M.vanbaalenii_PYR-1 KDA-EASIASIPGVAEVVPGQMAYATLAGQRIIMQGLARGSVAPPSQAMN
MAB_4672c|M.abscessus_ATCC_199 AEG-KDRLLKVPGVQSAEP----ILGLPSDFVHKGGHTAYFVVGYDTATG
TH_3409|M.thermoresistible__bu SPETIAQLAALPGVERVER-------MVEIEIALNDGSLAYVRAEDHPTF
MUL_0673|M.ulcerans_Agy99 PGGLASQLAALPGVSAVEP-----STTVAVTVRAGGRTYATTLTGFVPHS
MSMEG_2522|M.smegmatis_MC2_155 VADGPAPALTVPDGWRAVQ-------TSSGVVHIGDAEVSLRGDDEIPAG
*. . . .
Mb2592|M.bovis_AF2122/97 GPGMPRVSDGRAPSTPDE-VAVSSTLGR----NLGDDLQVG-----ARTL
Rv2563|M.tuberculosis_H37Rv GPGMPRVSDGRAPSTPDE-VAVSSTLGR----NLGDDLQVG-----ARTL
MMAR_0215|M.marinum_M GPGMPEVSDGRAPSKPDE-VAVSSTLNR----HIDDTLQLG-----AHKL
MAV_4427|M.avium_104 DRVRAEVLAGRGVVLTQN-LGKALNVRAGD--RLRLQTPHG-----PREA
Mvan_1005|M.vanbaalenii_PYR-1 DQVREQVLAGDGVVVSRD-IARSLGIGVGD--ELTLPTPTG-----QRRV
MAB_4672c|M.abscessus_ATCC_199 IGGPWSLAEGRNVAGSGE-VVLDRVLAKKNKIHLGDTVRLV-----DGDF
TH_3409|M.thermoresistible__bu PFPVLAGEDPEQTLAADQ-LIIGSVLAREERLRVGDPVRLGSGP-EARDM
MUL_0673|M.ulcerans_Agy99 SMHGFRGTDGRTLALSENGVLAGAALADKLDVRVGSDLIVIPAGGSPQHA
MSMEG_2522|M.smegmatis_MC2_155 QAVLGPDVANRLAVADGSVVDVNGHPLTARITGSGESVTVP-------TS
. :
Mb2592|M.bovis_AF2122/97 RIVGIVPESTALAKIP-------NIFLTTEGLQQLAYNGQPTISSI--GI
Rv2563|M.tuberculosis_H37Rv RIVGIVPESTALAKIP-------NIFLTTEGLQQLAYNGQPTISSI--GI
MMAR_0215|M.marinum_M RIVGIVPNSTALAKIP-------NIFLTTEGLQRVAYNGQPMITSI--GI
MAV_4427|M.avium_104 AVLAVVPFFSTVIGTVGMDLAQLRAWFDRPAATTLQITAAPGVDPR--RL
Mvan_1005|M.vanbaalenii_PYR-1 RVLEIVPFFSLLGGVVSMSLTLLREWYARPGSTVLAVNFTPGADRD--QV
MAB_4672c|M.abscessus_ATCC_199 TVVGLSKQTAAVGNFYAFISLVDAAHLLRAGNRVSYFLVQPTVGFTGDQV
TH_3409|M.thermoresistible__bu TVGTIVATPEVGGRRIYMPYRAAEEIFGPQAPGLVRIKPRDGVALD--QI
MUL_0673|M.ulcerans_Agy99 KLAGLVDEPLGTVLYATN-----STVAAITGSLVNGYLLRFGADADRAGL
MSMEG_2522|M.smegmatis_MC2_155 VARSLVGDHGWWTVYAPAGEENRRDLAQRFGAAVGLPYTADPSEQPKADG
: .
Mb2592|M.bovis_AF2122/97 DGMPR--QLPDGYQTVNRADAVSDLMRPLKVAVDAITVVAVLLWIVAALI
Rv2563|M.tuberculosis_H37Rv DGMPR--QLPDGYQTVNRADAVSDLMRPLKVAVDAITVVAVLLWIVAALI
MMAR_0215|M.marinum_M DGSPR--ELPEGYQTYDREGAVNDLIRPLKVAVNSISIVAVLLWIVAVLI
MAV_4427|M.avium_104 LADVRA-TVPAPNHVYDGRAALAGLQAPLHQSMFIANAVWIIVVAVAAVA
Mvan_1005|M.vanbaalenii_PYR-1 AATIRG-RVPADVLVYPGQEAAAAVGDSMAQGTALIDIMAWIVVFVAGVA
MAB_4672c|M.abscessus_ATCC_199 VDSVRK-SVPGMDAFTSETFAENSRAIVISMIGRPLRTMIGIAALVGVAL
TH_3409|M.thermoresistible__bu EADINATRFNQPIKVVDAAGYEAATAGGVSRFLTTLNALKYGLLAIAFVS
MUL_0673|M.ulcerans_Agy99 HADITS--LPGVLAYTDTHALENTVNRYLGLFWAFVGVMLALGGALAFVV
MSMEG_2522|M.smegmatis_MC2_155 EGLIYD-TVGGSGPLTFEQKFSALFSG--KVTSSTLGLISTIGLILGFVI
. : :.
Mb2592|M.bovis_AF2122/97 VGSVVYLSALERLRDFAVFKAIGVPTRSILAGLALQAVVVALLAAVVGG-
Rv2563|M.tuberculosis_H37Rv VGSVVYLSALERLRDFAVFKAIGVPTRSILAGLALQAVVVALLAAVVGG-
MMAR_0215|M.marinum_M VGSVVYLSALERMRDFAVFKAIGTPTHSIMAGLALQALVVSLLAAVVGV-
MAV_4427|M.avium_104 LLNTLTLSVTERRREIGVLRAMGAGRRFILRMVLAEAAGIGCVGGGLGF-
Mvan_1005|M.vanbaalenii_PYR-1 LLNTLMLSVLERRRELGMLRAMGSSRRFALRTVLAEAAGIGVVGAALGA-
MAB_4672c|M.abscessus_ATCC_199 VGLTVLAVTTEQMSDFGVLRALGVRPVQLCRTVIAQAALIAGLGYILGAG
TH_3409|M.thermoresistible__bu VTATLLLVGMRRRREMALLQALGATRGKVFAXXXLRRRRRGAPRPGVER-
MUL_0673|M.ulcerans_Agy99 IYITMTVNMAERTTELATLRAAGVSTPRLTATLTLENLLATAAALPFGLA
MSMEG_2522|M.smegmatis_MC2_155 AVSSFLAAVQERKREFGIMSSIG-LADEVLYFFLVESAIVFVAAYVLGVL
. .: ::. : : * . .
Mb2592|M.bovis_AF2122/97 ----ILSLLLAPLFPMTVVVPLSAFVALPAIATVIGLLASVAGLRRVVAI
Rv2563|M.tuberculosis_H37Rv ----ILSLLLAPLFPMTVVVPLSAFVALPAIATVIGLLASVAGLRRVVAI
MMAR_0215|M.marinum_M ----VLSKLLAPLFPMIVAVPGGAYLALPVVAILIGLLASVAGLKRVMTV
MAV_4427|M.avium_104 ----LLGLADQWLFSRISGDMMNFPVAFRLSPLALACTAGALGITLLGSV
Mvan_1005|M.vanbaalenii_PYR-1 ----VLGVVNQYLTAAALSNVLSIDVVYRPSPLAMLFACAAFGLTLLGAV
MAB_4672c|M.abscessus_ATCC_199 ITYGVQFLVKDRLGDVTVEVTPAMLAGMAAATGVMAVIGSLIPVRRVTRI
TH_3409|M.thermoresistible__bu --------------------------------RRRSRRRRPRPGRRPGAG
MUL_0673|M.ulcerans_Agy99 AGAGAAWLFLQSFNSDLFNMQLALGWSTLALAAVAVLAAAAISQLPAMRM
MSMEG_2522|M.smegmatis_MC2_155 G--AGAAVALTIPGIATPVAWAQAAGMVAAFLPAMAIVGALVPVHRLLQQ
Mb2592|M.bovis_AF2122/97 DPALAFGGP---------
Rv2563|M.tuberculosis_H37Rv DPALAFGGP---------
MMAR_0215|M.marinum_M DPALAFGGP---------
MAV_4427|M.avium_104 PPARRAARLNIIEAVSVN
Mvan_1005|M.vanbaalenii_PYR-1 PPAVRAARLDIVAAVAVD
MAB_4672c|M.abscessus_ATCC_199 DPAQAFRR----------
TH_3409|M.thermoresistible__bu PP----------------
MUL_0673|M.ulcerans_Agy99 VRERAQ------------
MSMEG_2522|M.smegmatis_MC2_155 RPVDLLGAR---------