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STQKGLAYGWLAARRRVREMVLPAITTATGAYLVVLVFGMSAGIREQSESLGYADEISRAVVLIAVTVLL VGVAEVAVVTTRTVAHRTRELGVLAANGVPRAPVVAALLVEPLLAAVLGALAGVLLAVVTGIVLGIAGLV ATGVSSAGLAAGSGIAVVVSVAAAVATSVVPTWKAASRPPVQSLASGA*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_4128 | - | - | 100% (189) | hypothetical protein Mflv_4128 |
M. gilvum PYR-GCK | Mflv_0321 | - | 7e-05 | 35.11% (131) | hypothetical protein Mflv_0321 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0073 | - | 2e-06 | 28.33% (120) | glutamine-transport transmembrane protein ABC transporter |
M. tuberculosis H37Rv | Rv0072 | - | 2e-06 | 28.33% (120) | glutamine-transport transmembrane protein ABC transporter |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | - | - | - | - | - |
M. marinum M | MMAR_0921 | - | 3e-05 | 29.69% (128) | ABC-type transporter |
M. avium 104 | MAV_4427 | - | 9e-05 | 40.00% (75) | efflux ABC transporter, permease protein |
M. smegmatis MC2 155 | MSMEG_2523 | - | 4e-72 | 74.59% (185) | efflux ABC transporter, permease protein, putative |
M. thermoresistible (build 8) | - | - | - | - | - |
M. ulcerans Agy99 | MUL_0673 | - | 2e-05 | 29.69% (128) | ABC-type transporter |
M. vanbaalenii PYR-1 | Mvan_2215 | - | 6e-82 | 84.04% (188) | hypothetical protein Mvan_2215 |
CLUSTAL 2.0.9 multiple sequence alignment Mb0073|M.bovis_AF2122/97 --------------MLFAALRDMQWRKRRLVITIISTGLIFGMTLVLTGL Rv0072|M.tuberculosis_H37Rv --------------MLFAALRDMQWRKRRLVITIISTGLIFGMTLVLTGL Mflv_4128|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2215|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_2523|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0921|M.marinum_M MTEVPTEPPRARPNWTLLRKTVRDLRRRPAQSVAIAVIVMLGVLLFIASY MUL_0673|M.ulcerans_Agy99 --------------------------------MAIAVIVMLGVLLFIASY MAV_4427|M.avium_104 ----------------MFSLRELAVHRRRTTASIAVMAVSATYLVAVFGI Mb0073|M.bovis_AF2122/97 ANGFRVEARHTVDSMGVDVFVVRSGAAGPFLGSIPFPDVDLARVAAEPGV Rv0072|M.tuberculosis_H37Rv ANGFRVEARHTVDSMGVDVFVVRSGAAGPFLGSIPFPDVDLARVAAEPGV Mflv_4128|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2215|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_2523|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0921|M.marinum_M DSFRNLTASYNRTYDRLHFADLTASGGDPTQLASAARELAGVENVATRVV MUL_0673|M.ulcerans_Agy99 DSFRNLTASYNRTYDRLHFADLTASGGDPTQLASAARELAGVENVATRVV MAV_4427|M.avium_104 FGSITGSVSRLADGIAGVAALEVSGITDAGFADSVLADVAAVPGVAT--- Mb0073|M.bovis_AF2122/97 MAAAP-------LGSVGTIMKEGTSTRNVTVFG-------APEHGPGMPR Rv0072|M.tuberculosis_H37Rv MAAAP-------LGSVGTIMKEGTSTRNVTVFG-------APEHGPGMPR Mflv_4128|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2215|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_2523|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0921|M.marinum_M RDRPVNIDGTKLIGRVVGLTGGGHGVDDVEIVDGRAPDPDAPAQVAIEKH MUL_0673|M.ulcerans_Agy99 RDRPVNIDGTQLIGRVVGLTGGGHGVDDVEIVDGRAPDPDAPAQVAIEKH MAV_4427|M.avium_104 -------------AAPMIRTTAATPSGPVLLLGVDARTAALGGALTDAVS Mb0073|M.bovis_AF2122/97 VSEGRSPSKPDEVAASSTMGRHLGDTVEVG---------ARRLRVVGIVP Rv0072|M.tuberculosis_H37Rv VSEGRSPSKPDEVAASSTMGRHLGDTVEVG---------ARRLRVVGIVP Mflv_4128|M.gilvum_PYR-GCK --------------MSTQKGLAYGWLAARR---------RVREMVLPAIT Mvan_2215|M.vanbaalenii_PYR-1 --------------MSAGKGLAYGWLAARR---------RVREMVLPAVT MSMEG_2523|M.smegmatis_MC2_155 ---------------MIQKGLAYGWLSARR---------RIREMVLPVVT MMAR_0921|M.marinum_M AAESFHLSPGDRVDVYNGSGWRTAEITGVARSPEYLWPARSRQDILPDPH MUL_0673|M.ulcerans_Agy99 AAESFQLSPGDRVDVYNGSGWRTAEITGVARSPEYLWPARSRQDILPDPH MAV_4427|M.avium_104 RPVRELSASPDGVQVGPRAGYAKGQAFQLGSAPVTVTEVLAGRQFAELNG * . . Mb0073|M.bovis_AF2122/97 NSTALAKIPNVFLTTEG-------LQKLAYNGQPNITSIGIIGMPRQLPE Rv0072|M.tuberculosis_H37Rv NSTALAKIPNVFLTTEG-------LQKLAYNGQPNITSIGIIGMPRQLPE Mflv_4128|M.gilvum_PYR-GCK TATGAYLVVLVFGMSAG-------IREQSES------------------- Mvan_2215|M.vanbaalenii_PYR-1 TGTGAFLVVLVFGMSDG-------IRAQSAS------------------- MSMEG_2523|M.smegmatis_MC2_155 TATGAFLVVLVFAMSAG-------IREQSAV------------------- MMAR_0921|M.marinum_M SFAVLFAPPRLAAQLTGQPGPNQTLVQMAAGATTADRDRVAGLLLSRGAL MUL_0673|M.ulcerans_Agy99 SFAVLFAPPRLAAQLTGQPGPNQTLVQMAAGATTADRDRVAGLLLSRGAL MAV_4427|M.avium_104 GHYVLAPLALAQRVTARAGQLDSILITLTPGADPAAVRAAVGAAVGGRAI : : Mb0073|M.bovis_AF2122/97 GYQTFDRVGAVNDLVRPLKVAVNSISIVAVLLWIVAVLIVGSVVYLSALE Rv0072|M.tuberculosis_H37Rv GYQTFDRVGAVNDLVRPLKVAVNSISIVAVLLWIVAVLIVGSVVYLSALE Mflv_4128|M.gilvum_PYR-GCK -------LGYADEISR-------AVVLIAVTVLLVGVAEVAVVTTRTVAH Mvan_2215|M.vanbaalenii_PYR-1 -------LGHGDEIAR-------AVVLIAVTVLLVGVAEVAVATTRTVAH MSMEG_2523|M.smegmatis_MC2_155 -------IGHAEEINR-------AVILIAVTVLLVGAVEVAVATTRTVAH MMAR_0921|M.marinum_M DVQTRDEQPSNAALHEDLNGFSELAVGFPVLFLTAAAIAEYVVVTRVVQA MUL_0673|M.ulcerans_Agy99 DVQTRDEQPSNAALHEDLNGFSELAVGFPVLFLTAAAIAEYVVVTRVVQA MAV_4427|M.avium_104 VAAPSSRAARAGDGVRLMN---YMALLGAAVALVVGAFLIYTTMTMAITQ . .. ... . Mb0073|M.bovis_AF2122/97 RLRDFAVFKAIGTPTRSIMAGLALQALVIALLAAVVGVVLAQVLA----- Rv0072|M.tuberculosis_H37Rv RLRDFAVFKAIGTPTRSIMAGLALQALVIALLAAVVGVVLAQVLA----- Mflv_4128|M.gilvum_PYR-GCK RTRELGVLAANGVPRAPVVAALLVEPLLAAVLGALAGVLLAVVTG----- Mvan_2215|M.vanbaalenii_PYR-1 RTRELGVLAANGVPRAPVVTALLVEPVVAAVLGALAGVGLAVLTG----- MSMEG_2523|M.smegmatis_MC2_155 RTRELGVLGANGIPRGPVVAALLVEPLVAAVLGALAGAGAASVTA----- MMAR_0921|M.marinum_M ERRIMGAMLAMGARPATVIRHYLGYGVAVATMGALLGVVLGAGAT----- MUL_0673|M.ulcerans_Agy99 ERRIMGAMLAMGARPATVIRHYLGYGVAVATMGALLGVVLGAGAT----- MAV_4427|M.avium_104 RRPVISMLRALGGRRRAVVGDLLAEAAVLGLIGGALGCGAGILAGRMAIG . :. : * * .:: . :.. * . Mb0073|M.bovis_AF2122/97 ------------------------PLFPMIVAVPVGAYLALP---VAAIV Rv0072|M.tuberculosis_H37Rv ------------------------PLFPMIVAVPVGAYLALP---VAAIV Mflv_4128|M.gilvum_PYR-GCK ------------------------IVLGIAGLVATGVSSAGL---AAGSG Mvan_2215|M.vanbaalenii_PYR-1 ------------------------IVLAALGIVATGVSYPGL---ALGGG MSMEG_2523|M.smegmatis_MC2_155 ------------------------ALVALAGLAPTGVSVAGI---LAGCL MMAR_0921|M.marinum_M ------------------------SLVTGLYTAAIGVPDTVVRHHVSTAV MUL_0673|M.ulcerans_Agy99 ------------------------SLVTGLYTAAIGVPDTVVRHHVSTAV MAV_4427|M.avium_104 RLPRAVTQGLEARVEYWLPGYAVPLALAATALTAVAAAAMAARQVYKVSP . .. .. Mb0073|M.bovis_AF2122/97 IGLFASVAGLKRVVTVDPAQAFGGP------------------------- Rv0072|M.tuberculosis_H37Rv IGLFASVAGLKRVVTVDPAQAFGGP------------------------- Mflv_4128|M.gilvum_PYR-GCK IAVVVSVAAAVATSVVPTWKAASRPPVQSLASGA---------------- Mvan_2215|M.vanbaalenii_PYR-1 IAVVVSIAAALATSIVPTWKAASRPPIRSLASGG---------------- MSMEG_2523|M.smegmatis_MC2_155 IAFGVSIVAAVATSFVPTWNAASRPPIRSLTAGG---------------- MMAR_0921|M.marinum_M LGFALGLATGLVAVLVPAITAARTAPADAMRGQRVLATAMGPLT------ MUL_0673|M.ulcerans_Agy99 LGFALGLATGLVAVLVPAITAARTAPADAMRGQRVLATAMGPLT------ MAV_4427|M.avium_104 VEALAPVGASAADAVPPWLRAASGVGALALFAVAALAVPAGAPTGVLLGA : : * Mb0073|M.bovis_AF2122/97 -------------------------------------------------- Rv0072|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_4128|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2215|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_2523|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0921|M.marinum_M -------------------RLTARWRLPAVIQLAVRSLTRSRGRTVATMV MUL_0673|M.ulcerans_Agy99 -------------------RLTARWRLPAVIQLAVRSLTRSRGRTVATMV MAV_4427|M.avium_104 VLVAELTAGFALTVPIVTATSALSRVFGSCGALAAATIRRAPRRVWATVM Mb0073|M.bovis_AF2122/97 -------------------------------------------------- Rv0072|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_4128|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2215|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_2523|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0921|M.marinum_M GGVLALILVLASVGMMTSMRAMLDVQFGEVQRQDASVLVAP-----SAAG MUL_0673|M.ulcerans_Agy99 GGVLALILVLASVGMMTSMRAMLDVQFGEVQRQDASALVAP-----SAAG MAV_4427|M.avium_104 TVLIGVLTTVVITGTNADMIGSARAIFAPVAEADVWVSADPPDSFPTDVL Mb0073|M.bovis_AF2122/97 -------------------------------------------------- Rv0072|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_4128|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2215|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_2523|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0921|M.marinum_M PGGLASQLAALPGVSAVEPSTTVAVTVRAGGRTYATTLTGFVPHSSMHGF MUL_0673|M.ulcerans_Agy99 PGGLASQLAALPGVSAVEPSTTVAVTVRAGGRTYATTLTGFVPHSSMHGF MAV_4427|M.avium_104 PQGLSERLAALPGAARVTEGACGFAVVAG----TRVLLDGFAAGSRDALF Mb0073|M.bovis_AF2122/97 -------------------------------------------------- Rv0072|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_4128|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2215|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_2523|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0921|M.marinum_M RGTDG--RTLALSENGVLAGAALADKLDVRVGSDLIVIPAGGSPQHAKLA MUL_0673|M.ulcerans_Agy99 RGTDG--RTLALSENGVLAGAALADKLDVRVGSDLIVIPAGGSPQHAKLA MAV_4427|M.avium_104 RALDDRVRAEVLAGRGVVLTQNLGKALNVRAGDRLRLQTPHGPREAAVLA Mb0073|M.bovis_AF2122/97 -------------------------------------------------- Rv0072|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_4128|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2215|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_2523|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0921|M.marinum_M GL--VDEPLGTVLYATNSTVAAITGSVVNGYLLRFGADADRAGLRADI-T MUL_0673|M.ulcerans_Agy99 GL--VDEPLGTVLYATNSTVAAITGSLVNGYLLRFGADADRAGLHADI-T MAV_4427|M.avium_104 VVPFFSTVIGTVGMDLAQLRAWFDRPAATTLQITAAPGVDPRRLLADVRA Mb0073|M.bovis_AF2122/97 -------------------------------------------------- Rv0072|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_4128|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2215|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_2523|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0921|M.marinum_M SLPGVLAYTDTHALENTVNRYLGLFWAFVGVMLALGGALAFVVIYVTMTV MUL_0673|M.ulcerans_Agy99 SLPGVLAYTDTHALENTVNRYLGLFWAFVGVMLALGGALAFVVIYITMTV MAV_4427|M.avium_104 TVPAPNHVYDGRAALAGLQAPLHQSMFIANAVWIIVVAVAAVALLNTLTL Mb0073|M.bovis_AF2122/97 -------------------------------------------------- Rv0072|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_4128|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2215|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_2523|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0921|M.marinum_M NMAERTTELATLRAAGVSTPRLTATLTLENLLATAAALPFGLAAGAGAAW MUL_0673|M.ulcerans_Agy99 NMAERTTELATLRAAGVSTPRLTATLTLENLLATAAALPFGLAAGAGAAW MAV_4427|M.avium_104 SVTERRREIGVLRAMGAGRRFILRMVLAEAAGIGCVGGGLGFLLGLADQW Mb0073|M.bovis_AF2122/97 -------------------------------------------------- Rv0072|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_4128|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2215|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_2523|M.smegmatis_MC2_155 -------------------------------------------------- MMAR_0921|M.marinum_M LFLQSFNSDLFNMQLALGWSTLALAAVA-VLAAAAISQLPAMRMVRDVDI MUL_0673|M.ulcerans_Agy99 LFLQSFNSDLFNMQLALGWSTLALAAVA-VLAAAAISQLPAMRMVR---- MAV_4427|M.avium_104 LFSR-ISGDMMNFPVAFRLSPLALACTAGALGITLLGSVPPARRAARLNI Mb0073|M.bovis_AF2122/97 --------- Rv0072|M.tuberculosis_H37Rv --------- Mflv_4128|M.gilvum_PYR-GCK --------- Mvan_2215|M.vanbaalenii_PYR-1 --------- MSMEG_2523|M.smegmatis_MC2_155 --------- MMAR_0921|M.marinum_M ARVVRERAQ MUL_0673|M.ulcerans_Agy99 -----ERAQ MAV_4427|M.avium_104 IEAVSVN--