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RARRLVMLRHGQTDYNVGSRMQGQLDTELSELGRTQAVAAAEVLGKRQPLLIVSSDLRRAYDTAVKLGER TGLVVRVDTRLRETHLGDWQGLTHAQIDADAPGARLAWREDATWAPHGGESRVDVAARSRPLVAELVASE PEWGGADEPDRPVVLVAHGGLIAALSAALLKLPVANWPALGGMGNASWTQLSGHWAPGSDFESIRWRLDV WNASAQVSSDVL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2419c | - | - | 100% (223) | PROBABLE PHOSPHOGLYCERATE MUTASE (PHOSPHOGLYCEROMUTASE) |
| M. tuberculosis H37Rv | Rv2228c | - | 4e-19 | 42.97% (128) | bifunctional RNase H/acid phosphatase |
| M. tuberculosis H37Rv | Rv0489 | gpmA | 4e-13 | 30.00% (190) | phosphoglyceromutase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2442c | - | 1e-127 | 99.55% (223) | phosphoglycerate mutase (phosphoglyceromutase) |
| M. gilvum PYR-GCK | Mflv_2655 | - | 1e-91 | 73.54% (223) | phosphoglycerate mutase |
| M. leprae Br4923 | MLBr_01452 | - | 1e-102 | 80.36% (224) | putative phosphoglycerate mutase |
| M. abscessus ATCC 19977 | MAB_1623 | - | 5e-91 | 75.45% (220) | phosphoglycerate mutase |
| M. marinum M | MMAR_3747 | gpm_1 | 1e-107 | 84.38% (224) | phosphoglycerate mutase, Gpm_1 |
| M. avium 104 | MAV_1752 | - | 1e-106 | 83.48% (224) | phosphoglycerate mutase family protein |
| M. smegmatis MC2 155 | MSMEG_4579 | - | 2e-96 | 77.09% (227) | phosphoglycerate mutase family protein |
| M. thermoresistible (build 8) | TH_0787 | - | 1e-98 | 77.49% (231) | PROBABLE PHOSPHOGLYCERATE MUTASE (PHOSPHOGLYCEROMUTASE) |
| M. ulcerans Agy99 | MUL_3691 | gpm_1 | 1e-106 | 83.48% (224) | phosphoglycerate mutase, Gpm_1 |
| M. vanbaalenii PYR-1 | Mvan_3924 | - | 2e-96 | 76.99% (226) | phosphoglycerate mutase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2419c|M.tuberculosis_H37Rv MRARRLVMLRHGQTDYNVGSRMQGQLDTELSELGRTQAVAAAEVLGKRQP
Mb2442c|M.bovis_AF2122/97 MRARRLVMLRHGQTDYNVGSRMQGQLDTELSELGRTQAVAAAEVLGKRQP
MLBr_01452|M.leprae_Br4923 MRTRRLVMLRHGQTDFNLGGRMQGQLDTELSELGRAQAVAVAEVLGKLQP
MAV_1752|M.avium_104 MKIRRLIMLRHGQTEFNAGSRMQGQLDSELSELGRAQAVAAAEVLGKAQP
MMAR_3747|M.marinum_M MTVRRLVMLRHGQTDYNLGSRMQGQLDTDLSDLGRAQAVAAAEVLGKLQP
MUL_3691|M.ulcerans_Agy99 MTVRRLVMLRHGQTDYNLGSRMQGQLDTDLSDLGRAQAVAAAEVLGKLQP
Mflv_2655|M.gilvum_PYR-GCK MTIRRLVMLRHGQTEYNAGSRMQGQLDTDLSDLGREQAASAADALAKRHP
Mvan_3924|M.vanbaalenii_PYR-1 MRVRRLVMLRHGQTEYNAGSRMQGQLDTDLSDLGREQAVAAAEVLAKRQP
MSMEG_4579|M.smegmatis_MC2_155 MRIRRLVMLRHGQTEYNAGSRMQGQLDTDLSDLGRDQAAAAAEVLAKRQP
TH_0787|M.thermoresistible__bu MRVRKLVMLRHGQTEYNAGSRMQGQLDTDLSDLGRAQAVAVAEVLSKRQP
MAB_1623|M.abscessus_ATCC_1997 -MIRRLVLLRHGQTTFNADSRMQGQLDTGLSDLGRAQAVAAAEVLAKRLP
*:*::****** :* ..*******: **:*** **.:.*:.*.* *
Rv2419c|M.tuberculosis_H37Rv LLIVSSDLRRAYDTAVKLGERTGLVVRVDTRLRETHLGDWQGLTHAQIDA
Mb2442c|M.bovis_AF2122/97 LLIVSSDLRRAYDTAVKLGERTGLVVRVDTRLRETHLGDWQGLTHAQIDA
MLBr_01452|M.leprae_Br4923 LRIVSSDLRRAYDTAIKLGERTGLKIWVDDRLREAHLGDWQGLTHSQIDA
MAV_1752|M.avium_104 LLIVSSDLHRAYDTAVRLGERTGLPIRVDRRLRETHLGDWQGLTHTQVDT
MMAR_3747|M.marinum_M LLIVSSDLRRAYDTATRLGERTGQQVRVDPRLRETHLGDWQGLTHTQIDA
MUL_3691|M.ulcerans_Agy99 LLIVSSDLRRAYDTATRLGERTGQQVRVDPRLRETHLGDWQGLTQTQIDA
Mflv_2655|M.gilvum_PYR-GCK LLIVSSDLRRALDTAVVLGDRCGQPVSIDARLRETHLGDWQGMTHLEVDE
Mvan_3924|M.vanbaalenii_PYR-1 LLIVSSDLRRALDTAVALGDRSGQPVSIDTRLRETHLGDWQGMTHLEVDA
MSMEG_4579|M.smegmatis_MC2_155 LLIVSSDLRRALDTAETLGTRAGVAVAVDKRLRETHLGDWQGLTHLEVDA
TH_0787|M.thermoresistible__bu LAIVSSDLRRAFDTAVELGDRSGLPVQVDPRLRETHLGEWQGLTHLEVDA
MAB_1623|M.abscessus_ATCC_1997 LAIVSSDLQRAYDTATALADRCHVGVSVDERLRETHLGDWQGLTHHEVDA
* ******:** *** *. * : :* ****:***:***:*: ::*
Rv2419c|M.tuberculosis_H37Rv DAPGARLAWREDATWAPHGGESRVDVAARSRPLVAELVASEPEWG---GA
Mb2442c|M.bovis_AF2122/97 DAPGARLAWREDATWAPHGGESRVDVAARSRPLVAELVASEPEWG---GA
MLBr_01452|M.leprae_Br4923 DAPGARLAWREDATWAPHSGESRVDVAARSLPVVTEVVSGAPEWG---DC
MAV_1752|M.avium_104 QAPGARLAWREDATWAPHGGESRVDVAARSVPVVAELVAGEPEWG---DP
MMAR_3747|M.marinum_M EAPGARLAWRENAEWAPHGGESRIDVAARSVPLVTELVSAEPEWG---GP
MUL_3691|M.ulcerans_Agy99 EAPGARLAWRENAEWAPHGGESRIDVAARSVPLVTELVSAEPEWG---GP
Mflv_2655|M.gilvum_PYR-GCK VAPGARLAWRDDARWAPHGGESRIDVARRSLPLVRELVTQQTEWG----S
Mvan_3924|M.vanbaalenii_PYR-1 AAPGARLAWRDDARWAPHGGESRVDVADRSLPLVHELVTQQTDWG----A
MSMEG_4579|M.smegmatis_MC2_155 AAPGARLAWRDDARWAPHGGESRVDVAERSLPLVVELVAQQSEWGLDRPG
TH_0787|M.thermoresistible__bu AAPGARLAWRDDARWAPHGGESRVDVAARSLPLVAELVAEHRDWG----A
MAB_1623|M.abscessus_ATCC_1997 IAPGARAAWRDDATLAPHGGESRIDVANRSVPLVAELVDSVTEWG----T
***** ***::* ***.****:*** ** *:* *:* :**
Rv2419c|M.tuberculosis_H37Rv DEPDRPVVLVAHGGLIAALSAALLKLPVANWPALGGMGNASWTQLSGHW-
Mb2442c|M.bovis_AF2122/97 DEPDRPVVLVAHGGLIAVLSAALLKLPVANWPALGGMGNASWTQLSGHW-
MLBr_01452|M.leprae_Br4923 HEPDRPVVLVAHGGLITALSAALLRLPVANWSILGSMGNASWVQLSGHS-
MAV_1752|M.avium_104 DGPDRPVVLVAHGGLIAALSAALLKLPVPNWPMLGGMGNASWVQLSGHS-
MMAR_3747|M.marinum_M TQADRPVVLVAHGGLIAALSAALLRLPVSNWPALGGMGNASWVQLSGHS-
MUL_3691|M.ulcerans_Agy99 TQADRPVVLVAHGGLIAALSAALLRLPVSNWPALGGMGNASWVQLSGHS-
Mflv_2655|M.gilvum_PYR-GCK AG-DRPVVLVAHGGLIAALTAALLGLPADNWPVLGGMGNASWVQLAGHTR
Mvan_3924|M.vanbaalenii_PYR-1 AGSDRPVVLVAHGGLIAALTAALLGLPVDNWPVLGGMGNASWVQLAGHTR
MSMEG_4579|M.smegmatis_MC2_155 AGAERPVVLVAHGGLIAALTAELLGLPVDNWPVLGGMGNASWVQLSGHS-
TH_0787|M.thermoresistible__bu DGQDRPVVLVAHGGLIAALTAALLGLPVDNWPALGGMGNASWVQLSGHGP
MAB_1623|M.abscessus_ATCC_1997 DERDHPVVLVAHGGLIAALTAALLRLDVSNWPVLGGMGNASWVQLGGHS-
::***********:.*:* ** * . **. **.******.**.**
Rv2419c|M.tuberculosis_H37Rv ---APG----SDFESIRWRLDVWNASAQVSSDVL
Mb2442c|M.bovis_AF2122/97 ---APG----SDFESIRWRLDVWNASAQVSSDVL
MLBr_01452|M.leprae_Br4923 ---DESD---SELDLIQWRLDVWNASVQVSNDVL
MAV_1752|M.avium_104 ---DDAA---DEFDDIRWRLDVWNASAQVANDVL
MMAR_3747|M.marinum_M ---DAAG---SDFDAIRWRLDVWNASAQVANDVL
MUL_3691|M.ulcerans_Agy99 ---DAAG---SDFDAIWWRLDVWNASAQVANDVL
Mflv_2655|M.gilvum_PYR-GCK ADGDPAS-----FDDIRWRLDVWNASAQVAGDVL
Mvan_3924|M.vanbaalenii_PYR-1 ADGDPGA-----FADIRWRLDVWNASAQVANDVL
MSMEG_4579|M.smegmatis_MC2_155 --ADDAE-----FADIRWRLDVWNASAQVANDVL
TH_0787|M.thermoresistible__bu ADPDGGDPDGSVFDRIRWRLDVWNASAQVAGDVL
MAB_1623|M.abscessus_ATCC_1997 --ADGAG-----FDDIRWRLDVWNASAQVTNDVL
. : * *********.**:.***