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M. marinum M MMAR_3747 (gpm_1)

annotation: phosphoglycerate mutase, Gpm_1
coordinates: 4613625 - 4614299
length: 224

TVRRLVMLRHGQTDYNLGSRMQGQLDTDLSDLGRAQAVAAAEVLGKLQPLLIVSSDLRRAYDTATRLGER
TGQQVRVDPRLRETHLGDWQGLTHTQIDAEAPGARLAWRENAEWAPHGGESRIDVAARSVPLVTELVSAE
PEWGGPTQADRPVVLVAHGGLIAALSAALLRLPVSNWPALGGMGNASWVQLSGHSDAAGSDFDAIRWRLD
VWNASAQVANDVL*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_3747gpm_1-100% (224)phosphoglycerate mutase, Gpm_1
M. marinum MMMAR_3304-2e-1737.98% (129) hypothetical protein MMAR_3304
M. marinum MMMAR_0814gpmA6e-1432.11% (190) phosphoglycerate mutase 1 Gpm1

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2442c-1e-10783.93% (224) phosphoglycerate mutase (phosphoglyceromutase)
M. gilvum PYR-GCKMflv_2655-8e-9574.78% (226) phosphoglycerate mutase
M. tuberculosis H37RvRv2419c-1e-10884.38% (224) phosphoglycerate mutase (phosphoglyceromutase)
M. leprae Br4923MLBr_01452-1e-10379.46% (224) putative phosphoglycerate mutase
M. abscessus ATCC 19977MAB_1623-6e-9176.58% (222) phosphoglycerate mutase
M. avium 104MAV_1752-1e-10883.04% (224) phosphoglycerate mutase family protein
M. smegmatis MC2 155MSMEG_4579-1e-9577.09% (227) phosphoglycerate mutase family protein
M. thermoresistible (build 8)TH_0787-2e-9977.49% (231) PROBABLE PHOSPHOGLYCERATE MUTASE (PHOSPHOGLYCEROMUTASE)
M. ulcerans Agy99MUL_3691gpm_11e-12699.11% (224) phosphoglycerate mutase, Gpm_1
M. vanbaalenii PYR-1Mvan_3924-2e-9777.43% (226) phosphoglycerate mutase

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_3747|M.marinum_M               MTVRRLVMLRHGQTDYNLGSRMQGQLDTDLSDLGRAQAVAAAEVLGKLQP
MUL_3691|M.ulcerans_Agy99           MTVRRLVMLRHGQTDYNLGSRMQGQLDTDLSDLGRAQAVAAAEVLGKLQP
Mb2442c|M.bovis_AF2122/97           MRARRLVMLRHGQTDYNVGSRMQGQLDTELSELGRTQAVAAAEVLGKRQP
Rv2419c|M.tuberculosis_H37Rv        MRARRLVMLRHGQTDYNVGSRMQGQLDTELSELGRTQAVAAAEVLGKRQP
MLBr_01452|M.leprae_Br4923          MRTRRLVMLRHGQTDFNLGGRMQGQLDTELSELGRAQAVAVAEVLGKLQP
MAV_1752|M.avium_104                MKIRRLIMLRHGQTEFNAGSRMQGQLDSELSELGRAQAVAAAEVLGKAQP
Mflv_2655|M.gilvum_PYR-GCK          MTIRRLVMLRHGQTEYNAGSRMQGQLDTDLSDLGREQAASAADALAKRHP
Mvan_3924|M.vanbaalenii_PYR-1       MRVRRLVMLRHGQTEYNAGSRMQGQLDTDLSDLGREQAVAAAEVLAKRQP
MSMEG_4579|M.smegmatis_MC2_155      MRIRRLVMLRHGQTEYNAGSRMQGQLDTDLSDLGRDQAAAAAEVLAKRQP
TH_0787|M.thermoresistible__bu      MRVRKLVMLRHGQTEYNAGSRMQGQLDTDLSDLGRAQAVAVAEVLSKRQP
MAB_1623|M.abscessus_ATCC_1997      -MIRRLVLLRHGQTTFNADSRMQGQLDTGLSDLGRAQAVAAAEVLAKRLP
                                       *:*::****** :* ..*******: **:*** **.:.*:.*.*  *

MMAR_3747|M.marinum_M               LLIVSSDLRRAYDTATRLGERTGQQVRVDPRLRETHLGDWQGLTHTQIDA
MUL_3691|M.ulcerans_Agy99           LLIVSSDLRRAYDTATRLGERTGQQVRVDPRLRETHLGDWQGLTQTQIDA
Mb2442c|M.bovis_AF2122/97           LLIVSSDLRRAYDTAVKLGERTGLVVRVDTRLRETHLGDWQGLTHAQIDA
Rv2419c|M.tuberculosis_H37Rv        LLIVSSDLRRAYDTAVKLGERTGLVVRVDTRLRETHLGDWQGLTHAQIDA
MLBr_01452|M.leprae_Br4923          LRIVSSDLRRAYDTAIKLGERTGLKIWVDDRLREAHLGDWQGLTHSQIDA
MAV_1752|M.avium_104                LLIVSSDLHRAYDTAVRLGERTGLPIRVDRRLRETHLGDWQGLTHTQVDT
Mflv_2655|M.gilvum_PYR-GCK          LLIVSSDLRRALDTAVVLGDRCGQPVSIDARLRETHLGDWQGMTHLEVDE
Mvan_3924|M.vanbaalenii_PYR-1       LLIVSSDLRRALDTAVALGDRSGQPVSIDTRLRETHLGDWQGMTHLEVDA
MSMEG_4579|M.smegmatis_MC2_155      LLIVSSDLRRALDTAETLGTRAGVAVAVDKRLRETHLGDWQGLTHLEVDA
TH_0787|M.thermoresistible__bu      LAIVSSDLRRAFDTAVELGDRSGLPVQVDPRLRETHLGEWQGLTHLEVDA
MAB_1623|M.abscessus_ATCC_1997      LAIVSSDLQRAYDTATALADRCHVGVSVDERLRETHLGDWQGLTHHEVDA
                                    * ******:** ***  *. *    : :* ****:***:***:*: ::* 

MMAR_3747|M.marinum_M               EAPGARLAWRENAEWAPHGGESRIDVAARSVPLVTELVSAEPEWG---GP
MUL_3691|M.ulcerans_Agy99           EAPGARLAWRENAEWAPHGGESRIDVAARSVPLVTELVSAEPEWG---GP
Mb2442c|M.bovis_AF2122/97           DAPGARLAWREDATWAPHGGESRVDVAARSRPLVAELVASEPEWG---GA
Rv2419c|M.tuberculosis_H37Rv        DAPGARLAWREDATWAPHGGESRVDVAARSRPLVAELVASEPEWG---GA
MLBr_01452|M.leprae_Br4923          DAPGARLAWREDATWAPHSGESRVDVAARSLPVVTEVVSGAPEWG---DC
MAV_1752|M.avium_104                QAPGARLAWREDATWAPHGGESRVDVAARSVPVVAELVAGEPEWG---DP
Mflv_2655|M.gilvum_PYR-GCK          VAPGARLAWRDDARWAPHGGESRIDVARRSLPLVRELVTQQTEWG----S
Mvan_3924|M.vanbaalenii_PYR-1       AAPGARLAWRDDARWAPHGGESRVDVADRSLPLVHELVTQQTDWG----A
MSMEG_4579|M.smegmatis_MC2_155      AAPGARLAWRDDARWAPHGGESRVDVAERSLPLVVELVAQQSEWGLDRPG
TH_0787|M.thermoresistible__bu      AAPGARLAWRDDARWAPHGGESRVDVAARSLPLVAELVAEHRDWG----A
MAB_1623|M.abscessus_ATCC_1997      IAPGARAAWRDDATLAPHGGESRIDVANRSVPLVAELVDSVTEWG----T
                                     ***** ***::*  ***.****:*** ** *:* *:*    :**     

MMAR_3747|M.marinum_M               TQADRPVVLVAHGGLIAALSAALLRLPVSNWPALGGMGNASWVQLSGHS-
MUL_3691|M.ulcerans_Agy99           TQADRPVVLVAHGGLIAALSAALLRLPVSNWPALGGMGNASWVQLSGHS-
Mb2442c|M.bovis_AF2122/97           DEPDRPVVLVAHGGLIAVLSAALLKLPVANWPALGGMGNASWTQLSGHW-
Rv2419c|M.tuberculosis_H37Rv        DEPDRPVVLVAHGGLIAALSAALLKLPVANWPALGGMGNASWTQLSGHW-
MLBr_01452|M.leprae_Br4923          HEPDRPVVLVAHGGLITALSAALLRLPVANWSILGSMGNASWVQLSGHS-
MAV_1752|M.avium_104                DGPDRPVVLVAHGGLIAALSAALLKLPVPNWPMLGGMGNASWVQLSGHS-
Mflv_2655|M.gilvum_PYR-GCK          AG-DRPVVLVAHGGLIAALTAALLGLPADNWPVLGGMGNASWVQLAGHTR
Mvan_3924|M.vanbaalenii_PYR-1       AGSDRPVVLVAHGGLIAALTAALLGLPVDNWPVLGGMGNASWVQLAGHTR
MSMEG_4579|M.smegmatis_MC2_155      AGAERPVVLVAHGGLIAALTAELLGLPVDNWPVLGGMGNASWVQLSGHS-
TH_0787|M.thermoresistible__bu      DGQDRPVVLVAHGGLIAALTAALLGLPVDNWPALGGMGNASWVQLSGHGP
MAB_1623|M.abscessus_ATCC_1997      DERDHPVVLVAHGGLIAALTAALLRLDVSNWPVLGGMGNASWVQLGGHS-
                                       ::***********:.*:* ** * . **. **.******.**.**  

MMAR_3747|M.marinum_M               ---DAAG---SDFDAIRWRLDVWNASAQVANDVL
MUL_3691|M.ulcerans_Agy99           ---DAAG---SDFDAIWWRLDVWNASAQVANDVL
Mb2442c|M.bovis_AF2122/97           ---APG----SDFESIRWRLDVWNASAQVSSDVL
Rv2419c|M.tuberculosis_H37Rv        ---APG----SDFESIRWRLDVWNASAQVSSDVL
MLBr_01452|M.leprae_Br4923          ---DESD---SELDLIQWRLDVWNASVQVSNDVL
MAV_1752|M.avium_104                ---DDAA---DEFDDIRWRLDVWNASAQVANDVL
Mflv_2655|M.gilvum_PYR-GCK          ADGDPAS-----FDDIRWRLDVWNASAQVAGDVL
Mvan_3924|M.vanbaalenii_PYR-1       ADGDPGA-----FADIRWRLDVWNASAQVANDVL
MSMEG_4579|M.smegmatis_MC2_155      --ADDAE-----FADIRWRLDVWNASAQVANDVL
TH_0787|M.thermoresistible__bu      ADPDGGDPDGSVFDRIRWRLDVWNASAQVAGDVL
MAB_1623|M.abscessus_ATCC_1997      --ADGAG-----FDDIRWRLDVWNASAQVTNDVL
                                         .      :  * *********.**:.***