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MIEITLLGTGSPIPDPDRAGPSTLVRAGGQVFLVDCGRGVLQRAAAVGVGAAGLSAVLLTHLHSDHIAEL GDVLITSWVTNFAADPAPLQVIGPPGTAETVEAMLKAFGRDIGYRIAHHADLNAPPPIEVHEYTDGTVWD RDGVAIRVAPTDHRPVAPTIGFRVEFDGASAVLAGGTVPCPSLDELAAGAGALVHTVIRKDIITNFPQQR VKDICDYHSSVQEAAATAARAGVGTLVMTHYVPAIIAGQEDQWRALAATEFGGRIELGNDLHRVEVHAR
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. ulcerans Agy99 | MUL_3670 | - | - | 100% (279) | ribonuclease Z |
M. ulcerans Agy99 | MUL_3909 | - | 9e-12 | 28.74% (247) | metal-dependent hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2430 | - | 1e-143 | 88.53% (279) | ribonuclease Z |
M. gilvum PYR-GCK | Mflv_2669 | - | 1e-122 | 75.81% (277) | ribonuclease Z |
M. tuberculosis H37Rv | Rv2407 | - | 1e-137 | 86.02% (279) | ribonuclease Z |
M. leprae Br4923 | MLBr_01173 | - | 2e-09 | 27.76% (245) | hypothetical protein MLBr_01173 |
M. abscessus ATCC 19977 | MAB_1483 | - | 3e-11 | 27.64% (246) | hypothetical protein MAB_1483 |
M. marinum M | MMAR_3727 | - | 1e-160 | 99.28% (279) | metal-dependent hydrolase |
M. avium 104 | MAV_1774 | - | 1e-133 | 80.94% (278) | ribonuclease Z |
M. smegmatis MC2 155 | MSMEG_4568 | - | 1e-125 | 77.26% (277) | ribonuclease Z |
M. thermoresistible (build 8) | TH_1457 | - | 1e-115 | 69.68% (277) | CONSERVED HYPOTHETCAL PROTEIN |
M. vanbaalenii PYR-1 | Mvan_3908 | - | 1e-122 | 75.45% (277) | ribonuclease Z |
CLUSTAL 2.0.9 multiple sequence alignment MUL_3670|M.ulcerans_Agy99 --------------MIEITLLGTGSPIPDPDRAGPSTLVRAG-GQVFLVD MMAR_3727|M.marinum_M --------------MIEITLLGTGSPIPDPDRAGPSTLVRAG-GQVFLVD Mb2430|M.bovis_AF2122/97 --------------MLEITLLGTGSPIPDPDRAGPSTLVRAG-AQAFLVD Rv2407|M.tuberculosis_H37Rv --------------MLEITLLGTGSPIPDPDRAGPSTLVRAG-AQAFLVD MAV_1774|M.avium_104 --------------MIEVTLLGTGSPIPDPNRAGPSTLVRAG-GQVFLVD Mflv_2669|M.gilvum_PYR-GCK --------------MIEVTLLGTGSPIPDARRAGPSTLVRAG-GQTFLVD Mvan_3908|M.vanbaalenii_PYR-1 MSPVGRPPRVTSGLMIEVTLLGTGSPIPDARRAGPSTLVRAG-GQTFLVD MSMEG_4568|M.smegmatis_MC2_155 --------------MIEVTLLGTGSPIPDPDRAGPSTMVRAG-GQTFLVD TH_1457|M.thermoresistible__bu --------------MIEVTLLGTGSPVPDAHRAGPSTLVRAG-HQTLLID MLBr_01173|M.leprae_Br4923 -------------MTVRITVLGCSGSVVGPDSPASGYLLRAPDTPPLVLD MAB_1483|M.abscessus_ATCC_1997 ---------------MRVTVLGCSGSVTGPDSPASGYLLTAPDAPPLVID :.:*:** ...: .. .... :: * :::* MUL_3670|M.ulcerans_Agy99 CGRGVLQRAAAVGVGAAGLSAVLLTHLHSDHIAELGDVLITSWVTNFAAD MMAR_3727|M.marinum_M CGRGVLQRAAAVGVGAAGLSAVLLTHLHSDHIAELGDVLITSWVTNFAAD Mb2430|M.bovis_AF2122/97 CGRGVLQRAAAVGVGAAGLSAVLLTHLHSDHIAELGDVLITSWVTNFAAD Rv2407|M.tuberculosis_H37Rv CGRGVLQRAAAVGVGAAGLSAVLLTHLH-------GDVLITSWVTNFAAD MAV_1774|M.avium_104 CGRGVLQRAAAVGVGAAGLSTLLLTHLHSDHVGDLGDVLITRWVSTFTPD Mflv_2669|M.gilvum_PYR-GCK CGRGVLQRAAAVGVGANQISALLLTHLHSDHIADLGDVLITRWVSNFAPD Mvan_3908|M.vanbaalenii_PYR-1 CGRGVLQRLAAVGVGANNITALLLTHLHSDHIADLGDVLITRWVSNFAPD MSMEG_4568|M.smegmatis_MC2_155 CGRGVLQRLAAAGSSASQLSALLLTHLHSDHIADLGDVIITRWVSTFTPD TH_1457|M.thermoresistible__bu CGRGVQQRMAGAETSATALTALLLTHLHSDHIADLGDLLITRWISNFDPQ MLBr_01173|M.leprae_Br4923 FGGGVLG--ALQRHADPGSVHVLLSHLHADHCLDMPGLFVWRRYHPTRPV MAB_1483|M.abscessus_ATCC_1997 FGGGVLG--SLQRFADPGSVSVLLSHLHADHCLDLPGLFVWRRYHPNPPK * ** : . :**:*** .::: . MUL_3670|M.ulcerans_Agy99 PAPLQVIGPPGTAETVEAMLKAFGRDIGYRIAHHADLNAPPPIEVHEYTD MMAR_3727|M.marinum_M PAPLQVIGPPGTAETVDAMLKAFGRDIGYRIAHHADLNAPPPIEVHEYTD Mb2430|M.bovis_AF2122/97 PAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHADLTTPPPIEVHEYTA Rv2407|M.tuberculosis_H37Rv PAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHADLTTPPPIEVHEYTA MAV_1774|M.avium_104 PVPLPIIGPPGTAELVAATLNALRHDIGYRIAHHADLNAPPAVDVREHTD Mflv_2669|M.gilvum_PYR-GCK LPPLPIIGPPGTAEVVENMLKAFSFDIGYRIAHHDDLTTPPPVEVEEVTD Mvan_3908|M.vanbaalenii_PYR-1 LAPLPIIGPPGTAEVVENTLKAFGFDIGYRIAHHADLTTPPPVEVEEVTE MSMEG_4568|M.smegmatis_MC2_155 APPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHDDLTAPPPVEVHEHTE TH_1457|M.thermoresistible__bu LPPLPIIGPPGTAEVVSATLRAFGHDIGYRMKHHADLTTPPQVDVKEATE MLBr_01173|M.leprae_Br4923 GKAL-LYGPDDTWLRLGAASSPYGGEID---------DCSDIFDVRHWVD MAB_1483|M.abscessus_ATCC_1997 GKAI-MYGPADTLVRVGAASAEIGGEVD---------DFTDIFDVFPWAD .: : ** .* : ::. . .:* . MUL_3670|M.ulcerans_Agy99 GTVWDRDGVAIRVAPTDHRPVAPTIGFRVEF-DGASAVLAGGTVPCPSLD MMAR_3727|M.marinum_M GTVWDRDGVAIRVAPTDHRPVAPTIGFRVEF-DGASAVLAGDTVPCPSLD Mb2430|M.bovis_AF2122/97 GPAWDRDGVTIRVAPTDHRPVTPTIGFRIES-DGASVVLAGDTVPCDSLD Rv2407|M.tuberculosis_H37Rv GPAWDRDGVTIRVAPTDHRPVTPTIGFRIES-DGASVVLAGDTVPCDSLD MAV_1774|M.avium_104 GPVWDRDGVSIRVAPTDHRPVAPTIGFRVDY-QGASVVLAGDTVPCAGLD Mflv_2669|M.gilvum_PYR-GCK GVVWGRDEVSIRVGPTDHRPVTPTIGFRIEH-HGASVVLAGDTVPCRGLD Mvan_3908|M.vanbaalenii_PYR-1 GVVWGRDEVSIRVGPTDHRPVTPTIGFRIEH-NGASVVLAGDTVPCRGLD MSMEG_4568|M.smegmatis_MC2_155 GVVWDRDGVVIRVGPTDHRPVTPTIAFRVEH-ADASVVAAGDSVPCATLD TH_1457|M.thermoresistible__bu GVVWDVDGVRIRVAPTDHRPVTPTIGFRVEH-DGASVVLAGDTVPCESLD MLBr_01173|M.leprae_Br4923 GEPVPLG--ALMIMPRLVAHPTESYGLRITDPSGASLVYSGDTGSCDQLV MAB_1483|M.abscessus_ATCC_1997 GEPVQFG--SLTVTPTRVAHPPESYGLRIEDSSGTVLAYSGDTGICDAVV * . : : * . : .:*: .: . :*.: * : MUL_3670|M.ulcerans_Agy99 ELAAGAGALVHTVIRKDIITNFPQQRVKDICDYHSSVQEAAATAARAGVG MMAR_3727|M.marinum_M ELAAGAGALVHTVIRKDIITNFPQQRVKDICDYHSSVQEAAATAARAGVG Mb2430|M.bovis_AF2122/97 QLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVG Rv2407|M.tuberculosis_H37Rv QLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVG MAV_1774|M.avium_104 ELAAGAGALVHTVIRKDIVATIPQQRLQDICDYHSSVEQAAATAARAGVG Mflv_2669|M.gilvum_PYR-GCK KLAAGAGALVHTVIRRDLIEALPMQRIRDICDYHSSVEQAAETATRAGVG Mvan_3908|M.vanbaalenii_PYR-1 ELAAGAGALVHTVIRPDLIEAMPVQRIRDICDYHSSVEQAADTATRAGVG MSMEG_4568|M.smegmatis_MC2_155 ALATGAGALIHTVIRKDIIETLPQQRIRDICDYHSSVQEAAATAARAGVG TH_1457|M.thermoresistible__bu ELAAGAGAMVHTVIRKELIAQLPQQRIREICEYHSSPQEAGATAERAGVG MLBr_01173|M.leprae_Br4923 ELARGADVFLCEASWTHSP-DRPPN-------LHLSGTEAGRAAAQASVR MAB_1483|M.abscessus_ATCC_1997 DLARGADVFLCEASWTHMPGHRPPD-------LHLSGTEAGQIATRAGVK ** **..:: . . * : * * :*. * :*.* MUL_3670|M.ulcerans_Agy99 TLVMTHYVPAIIAGQEDQWRALAATEFGGRIELGNDLHRVEVHAR----- MMAR_3727|M.marinum_M TLVMTHYVPAIIAGQEDQWRALAATEFGGRIELGNDLHRVEVHAR----- Mb2430|M.bovis_AF2122/97 TLVMTHYVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHPRR---- Rv2407|M.tuberculosis_H37Rv TLVMTHYVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHPRR---- MAV_1774|M.avium_104 TLVMTHYVPALVAGQEEQWRALAAREFAGRVELGDDLHRVQVDAPS---- Mflv_2669|M.gilvum_PYR-GCK ILILTHYVPTLQPGQEDDWRALAATRFDRQIEIGDDLHRVQVHPGVCAKP Mvan_3908|M.vanbaalenii_PYR-1 ILILTHYVPTLQPGQEEDWRALAASVFDRQIEIGDDLHRVEVHPGVGARP MSMEG_4568|M.smegmatis_MC2_155 ILILTHYVPAIAPGTEDQWRELAATEFDRQIEVGADLHRVEVHPGVCVKP TH_1457|M.thermoresistible__bu ILILTHYLPPVQPGQEDEWRAQAATTFSRQIEVGDDLHRVQVHPGVGSAR MLBr_01173|M.leprae_Br4923 ELLLTHIPPWTS---REDVISEAKAEFDGPVHAVVSGETFDIQAPERV-- MAB_1483|M.abscessus_ATCC_1997 ELLLTHIPPWTS---REDVIAEAKSAFDGPVHAVVAGENIDL-------- *::** * .:: * * :. . .:: MUL_3670|M.ulcerans_Agy99 ----- MMAR_3727|M.marinum_M ----- Mb2430|M.bovis_AF2122/97 ----- Rv2407|M.tuberculosis_H37Rv ----- MAV_1774|M.avium_104 ----- Mflv_2669|M.gilvum_PYR-GCK AG--- Mvan_3908|M.vanbaalenii_PYR-1 AG--- MSMEG_4568|M.smegmatis_MC2_155 AG--- TH_1457|M.thermoresistible__bu FGTSP MLBr_01173|M.leprae_Br4923 ----- MAB_1483|M.abscessus_ATCC_1997 -----