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M. tuberculosis H37Rv Rv2384 (mbtA)

annotation: BIFUNCTIONAL ENZYME MBTA: SALICYL-AMP LIGASE (SAL-AMP LIGASE) + SALICYL-S-ArCP SYNTHETASE
coordinates: 2675936 - 2677633
length: 565

MPPKAADGRRPSPDGGLGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGG
LSYAELDQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGHFAAV
SAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTGSPAPPADPGSPALL
LVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVVLAAGHNFPLACPGLLGAMTVGATAVFAP
DPSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWEPVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQ
QVFGMAEGLLNFTRIGDPPEVVEHTQGRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAER
DNERCFDPDGFYRSGDLVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQY
LGEKICAAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAIVRQLGIATGPVT
TQRCH
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2384mbtA-100% (565)BIFUNCTIONAL ENZYME MBTA: SALICYL-AMP LIGASE (SAL-AMP LIGASE) + SALICYL-S-ArCP SYNTHETASE
M. tuberculosis H37RvRv0119fadD78e-4229.03% (534) acyl-CoA synthetase
M. tuberculosis H37RvRv3561fadD36e-3829.10% (536) acyl-CoA synthetase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2405mbtA0.0100.00% (565) bifunctional salicyl-AMP ligase/salicyl-S-arcp synthetase
M. gilvum PYR-GCKMflv_2691-0.065.06% (538) AMP-dependent synthetase and ligase
M. leprae Br4923MLBr_02661-2e-3326.61% (545) acyl-CoA synthetase
M. abscessus ATCC 19977MAB_2247c-0.061.64% (550) bifunctional salicyl-AMP ligase/salicyl-S-arcp synthetase
M. marinum MMMAR_3698mbtA0.072.07% (555) bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP
M. avium 104MAV_2008-0.078.33% (540) 2,3-dihydroxybenzoate-AMP ligase
M. smegmatis MC2 155MSMEG_4516-0.069.19% (555) 2,3-dihydroxybenzoate-AMP ligase
M. thermoresistible (build 8)TH_2907-0.064.58% (542) PUTATIVE AMP-dependent synthetase and ligase
M. ulcerans Agy99MUL_3641mbtA0.072.91% (539) bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP
M. vanbaalenii PYR-1Mvan_3850-0.063.57% (538) AMP-dependent synthetase and ligase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2691|M.gilvum_PYR-GCK          ---MTTGFPIEYGHGLTNGDLKHGFVPFPEDRAEAYRRAGYWTGRPLDSI
Mvan_3850|M.vanbaalenii_PYR-1       ---MNTGLPADQGN-----DLTRGFVPFPPDRAEVYRRAGYWTGRPLDSI
TH_2907|M.thermoresistible__bu      ---MTTEFQPVESDLTS--DFRTGFVPFPPDRVEEYRRAGYWTGRRLDSI
Rv2384|M.tuberculosis_H37Rv         -----MPPKAADGRRPSPDGGLGGFVPFPADRAASYRAAGYWSGRTLDTV
Mb2405|M.bovis_AF2122/97            -----MPPKAADGRRPSPDGGLGGFVPFPADRAASYRAAGYWSGRTLDTV
MAV_2008|M.avium_104                -----MSPNTT-----PPAGVLDGFVPFPAERAAAYRAAGLWTGRALDTI
MMAR_3698|M.marinum_M               -----MPVTSA---QPPRPGPVAGFIPYPPERVASYRAAGYWTGRSIGSL
MUL_3641|M.ulcerans_Agy99           ---------------------MAGFIPYPPERVASYRAAGYWTGRSIGSL
MSMEG_4516|M.smegmatis_MC2_155      MTLTTPHPRPEQSESAAQSSLLAGFTPFPAERAQAYRAAGYWRDQLLDSV
MAB_2247c|M.abscessus_ATCC_199      ----MTQPRSTTTASSAATPALDGFVPFPSVRADEYRRAGYWTGNTVESL
MLBr_02661|M.leprae_Br4923          ------------------MKSESITSSRAPVEQIDARLTGQFESPSIASL
                                                              . .  .    * :* : .  : ::

Mflv_2691|M.gilvum_PYR-GCK          LTDAASRWPDKPAIIDAT-----RSYTFAELDAAADRAAAGLADLGIRPG
Mvan_3850|M.vanbaalenii_PYR-1       LTEAAATWPDKPAVIDSA-----QTYTFRELDAAADRVAAGLAALGIRPG
TH_2907|M.thermoresistible__bu      LSDAAAAQPDKAAVIDPD-----RSHTFAELDALADRVAAGLADLGIAPG
Rv2384|M.tuberculosis_H37Rv         LSDAARRWPDRLAVADAGDRPGHGGLSYAELDQRADRAAAALHGLGITPG
Mb2405|M.bovis_AF2122/97            LSDAARRWPDRLAVADAGDRPGHGGLSYAELDQRADRAAAALHGLGITPG
MAV_2008|M.avium_104                LTDAARRWPDRTAVLDAS---GGTGFSYAGLDEQANRAAAGLADAGIAPG
MMAR_3698|M.marinum_M               LRQAAARWPDRVGVVDAG-----ASHTFCELDKLADRAAAGFVSLGIAPG
MUL_3641|M.ulcerans_Agy99           LRQAAARWPDRVGVVDAG-----ASHTFCELDKLADRVAAGFVSLGIAPG
MSMEG_4516|M.smegmatis_MC2_155      LRTAARTWPDHIAVIDAD-----HRHTYAELDRLADRAAAGIAGLGIRPG
MAB_2247c|M.abscessus_ATCC_199      LRVSAARRPCHPAVIDEH-----RALSYRELDEAADNAAHAFLRLGIAPG
MLBr_02661|M.leprae_Br4923          VEAAAIRNPSAPALVVTDN---RIVVSYRDLLRLVDDLTVQLALGGLLPG
                                    :  :*   *   .:            ::  *   .:  :  :   *: **

Mflv_2691|M.gilvum_PYR-GCK          ERVLLQLPNSCQFAVALFALLRAGVVPVMCLTGHRTAELGHFADVSGAVA
Mvan_3850|M.vanbaalenii_PYR-1       DRVLLQLPNSCQFAIALFGLLRAAAVPVMCLPGHRTAELGHFAEVSGAVA
TH_2907|M.thermoresistible__bu      DRVLLQMPNDTRFAVAFFGLLRAGAIPVMCLPGHRSAEMSHFAEVSGAVG
Rv2384|M.tuberculosis_H37Rv         DRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGHFAAVSAATG
Mb2405|M.bovis_AF2122/97            DRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGHFAAVSAATG
MAV_2008|M.avium_104                DRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGHFAALSQATA
MMAR_3698|M.marinum_M               DRVLLQLPNSCRFAVALFGLLRAGAIPVMCLPGHRLAELHHFAEVSGAVG
MUL_3641|M.ulcerans_Agy99           DRVLLQLPNSCRFAVALFGLLRAGAIPVMCLPGHRLAELHHFAEVSGAVG
MSMEG_4516|M.smegmatis_MC2_155      DRVLVQLPNTAEFAVALFGLLRAGAVPVMCLPGHRLAELTHFAEVSSAVA
MAB_2247c|M.abscessus_ATCC_199      DRVLLQLPNRASFAVALFGLMRAGAIPVMCLPGHRAAELSHFIEVADAVG
MLBr_02661|M.leprae_Br4923          DRVALCAASNIEFVVGLLAASRAGLIVVPLDPALPVNEQCIRSQAAGVRV
                                    :** :  ..   *.:.::.  **. : *   ..    *       : .  

Mflv_2691|M.gilvum_PYR-GCK          VIVPDRAGGFDYRDMAASLAAQRPALRHVIVDGEPGD----QVSWQSILD
Mvan_3850|M.vanbaalenii_PYR-1       LIVPDEAGGFDYRDMAGRLAAEHPSLQHVIVDGENGP----FVAWSSIRD
TH_2907|M.thermoresistible__bu      LIIPERANGFDYRELARALTASRPRLRHVIVDGATDPSGDGFVPWSALAE
Rv2384|M.tuberculosis_H37Rv         LVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGP----FVSWAQLCA
Mb2405|M.bovis_AF2122/97            LVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGP----FVSWAQLCA
MAV_2008|M.avium_104                LLIADTAAGFDYRTMAAGLVEEHEALAHVIVDGDPGP----FLSWAQLCE
MMAR_3698|M.marinum_M               LIVAQHAGGFDYRSMAERLVAAHPQLRHVIIDGESGP----FLPWSSLSE
MUL_3641|M.ulcerans_Agy99           LIVAQHAGGFDYRSMAERLVAAHPQLRHVIIDGESGP----FLPWSSLSE
MSMEG_4516|M.smegmatis_MC2_155      LVVADTAGGFDHRDLARELVRSHPDVRHVLVDGDAAE----FLSWAEVTR
MAB_2247c|M.abscessus_ATCC_199      LVIPDSAGGFDYRALAVALSQRHPRLRTVVVEGDAGP----FASWTSLLK
MLBr_02661|M.leprae_Br4923          TLVDSLALEGVSDQRAATMRYWPIAVSYGSVTGASEGS---LLVHLDDTA
                                     :: . *        *  :      :    : *                 

Mflv_2691|M.gilvum_PYR-GCK          FAGPRLGRTPVDPSLPALLLVSGGTTGLPKLIARTHDDYVYNAHACAQAC
Mvan_3850|M.vanbaalenii_PYR-1       FDGPAVERAAVDPGLPALLLVSGGTTGLPKLIARTHDDYVYNAVASAQAC
TH_2907|M.thermoresistible__bu      FAGPAVPRPPVDTTAPALLLVSGGTTGLPKLIPRTHDDYVYTAVASARAY
Rv2384|M.tuberculosis_H37Rv         QAGTGSPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALC
Mb2405|M.bovis_AF2122/97            QAGTGSPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALC
MAV_2008|M.avium_104                RAPAGRPATPVDPGSPALLLVSGGTTGTPKLIPRTHDDYVFNANASAELC
MMAR_3698|M.marinum_M               GA---TPDIDVDTTSPALLLVSGGTTGTPKLIPRTHDDYVYNATASAQLC
MUL_3641|M.ulcerans_Agy99           GA---TPDIDVDTTSPALLLVSGGTTGTPKLIPRTHDDYVYNATASAQLC
MSMEG_4516|M.smegmatis_MC2_155      AAPGPVPEIAPDPAAPALLLVSGGTTGAPKLIPRTHQDYVYNATASAELC
MAB_2247c|M.abscessus_ATCC_199      SVEPQGPLPTVQTDTPALLLVSGGTTAAPKLIPRTHEDYVYNATQAARVC
MLBr_02661|M.leprae_Br4923          ALHPVTSTPDGLRHDDAMIMFTGGTTGLPKMVPWTDGNIAGSVHAIITAY
                                                    *:::.:****. **::. *. : . ..       

Mflv_2691|M.gilvum_PYR-GCK          EMTGEDAYLVALPAGHNFPLACPGLLGSMTVGAPTVFTADP--SPENAFA
Mvan_3850|M.vanbaalenii_PYR-1       EMTAEDAYLVALPAGHNFPLACPGMLGSMTVGAPTVFTADP--SPENAFA
TH_2907|M.thermoresistible__bu      EMTSDDVYLVVLPAAHNFPLACPGMLGAMTVGASTVFTADP--SPEAAFP
Rv2384|M.tuberculosis_H37Rv         RLSADDVYLVVLAAGHNFPLACPGLLGAMTVGATAVFAPDP--SPEAAFA
Mb2405|M.bovis_AF2122/97            RLSADDVYLVVLAAGHNFPLACPGLLGAMTVGATAVFAPDP--SPEAAFA
MAV_2008|M.avium_104                GLTRDDVYLAVLSAGHNFPLACPGLLGAMTVGATTVFGTDP--SPEAAFA
MMAR_3698|M.marinum_M               RLTADDVYLVSLPAAHNFPLACPGILGSMAVGATIVFSTDP--SPEAAFT
MUL_3641|M.ulcerans_Agy99           RLTADDVYLVSLPAAHNFPLACPGILGSMAVGATIVFSTDP--SPEAAFT
MSMEG_4516|M.smegmatis_MC2_155      RLTADDVYLVALPAAHNFPLACPGLLGAMTVGATTVFTTDP--SPEAAFA
MAB_2247c|M.abscessus_ATCC_199      GLTQDDVYLVALPAGHNFPLACPGLLGAISTGATTVFLSDP--SPESAFA
MLBr_02661|M.leprae_Br4923          QLGPQDATVVVMPLYHGHGLIAA-LLSTLASGGVVLLPARARFSARTFWD
                                     :  :*. :. :.  *.. * .. :*.::: *.  :: . .  *..  : 

Mflv_2691|M.gilvum_PYR-GCK          LIDKHRITVTGLVNALAKLWAQACDWEPVLPT--SLRFVQVGGSRMSPEE
Mvan_3850|M.vanbaalenii_PYR-1       LIDKFRITVTGLVNALAKLWAQACEWEPVLPT--SLRFVQVGGSRMSPEE
TH_2907|M.thermoresistible__bu      LINRHRVTVTGLVNALAKLWAQACEWEPELPE--SLRVVQVGGSRMSPQE
Rv2384|M.tuberculosis_H37Rv         AIERHGVTVTALVPALAKLWAQSCEWEPVTPK--SLRLLQVGGSKLEPED
Mb2405|M.bovis_AF2122/97            AIERHGVTVTALVPALAKLWAQSCEWEPVTPK--SLRLLQVGGSKLEPED
MAV_2008|M.avium_104                TIARHGVTVTALVPALAKLWAHACEWEDNPPK--SLRLLQVGGAKLEADD
MMAR_3698|M.marinum_M               LIERHGVTVTALVPALAKLWTQACDWEPVTPK--SLRLLQVGGSRLEPED
MUL_3641|M.ulcerans_Agy99           LIERHGVTVTALVPALAKLWTQACDWEPVIPK--SLRLLQVGGSRLEPED
MSMEG_4516|M.smegmatis_MC2_155      AIDEHGVTATALVPALAKLWAQACAWEPLAPK--TLRLLQVGGAKLAAPD
MAB_2247c|M.abscessus_ATCC_199      TIARHRVSVTAVVPSLAQLWAQATAWEPVLPE--TLRLLQVGGAKLGADD
MLBr_02661|M.leprae_Br4923          DIDAVAATWYTAAPAIHRILLELASTQSFRSKRAKLRFIRSCSAPLTQET
                                     *     :    . :: ::  .    :   .   .**.::  .: :    

Mflv_2691|M.gilvum_PYR-GCK          ARFILDRLTPGMSQIFGMAEGMLNFTRP-----GDPEDVVVHTQGRPMSP
Mvan_3850|M.vanbaalenii_PYR-1       ARFILERLTPGMSQIFGMAEGMLNFTRP-----GDPEDVVVHTQGRPMSP
TH_2907|M.thermoresistible__bu      AQFILDRLTPGMSQIFGMAEGMLNFTRP-----GDPIDVVVHTQGRPMSP
Rv2384|M.tuberculosis_H37Rv         ARRVRTALTPGLQQVFGMAEGLLNFTRI-----GDPPEVVEHTQGRPLCP
Mb2405|M.bovis_AF2122/97            ARRVRTALTPGLQQVFGMAEGLLNFTRI-----GDPPEVVEHTQGRPLCP
MAV_2008|M.avium_104                ARVIRSALTPGLQQVFGMAEGLLNYTRL-----DDPPEITEHTQGRPLST
MMAR_3698|M.marinum_M               ARQAREALTPGLQQVFGMAEGLLNFTRL-----EDPPDLLEHTQGRPLCS
MUL_3641|M.ulcerans_Agy99           ARQAREALTPGLQQVFGMAEGLLNFTRL-----EDPPDLLEHTQGRPLCS
MSMEG_4516|M.smegmatis_MC2_155      AALVRGALTPGLQQVFGMAEGLLNYTRI-----GDPPEVLENTQGRPLSP
MAB_2247c|M.abscessus_ATCC_199      ARAVRESLTQGLQQVFGMAEGLLCLTQP-----GDPTDILDNSQGRPMCD
MLBr_02661|M.leprae_Br4923          AQALREEFLAPVICAFGMTEATHQVTTTNIKWFGQGENPTVTNGLVGQST
                                    *      :   :   ***:*.    *        :  :    .     . 

Mflv_2691|M.gilvum_PYR-GCK          HDEMRVVDEDGVEVAPGEEGELLVRGPYTLNGYYRADDANARSFTPDGFY
Mvan_3850|M.vanbaalenii_PYR-1       HDEVRVVDESGDGVPPGEEGELLVRGPYTLYGYYRDDDANARSFSPDGFY
TH_2907|M.thermoresistible__bu      HDEMRVVDESGAEVAPGEEGELLVRGPNTLNGYYRDDEANARSFSPDGFY
Rv2384|M.tuberculosis_H37Rv         ADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFY
Mb2405|M.bovis_AF2122/97            ADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFY
MAV_2008|M.avium_104                ADEVRVVDAAGNPVAPGQEGELLVRGPYTFNGYFRAERDNQRCFDAQGFF
MMAR_3698|M.marinum_M               ADELRIVDGAGAPVAPGAEGELLVRGPYTINGYFCADRDNERCFDPAGFY
MUL_3641|M.ulcerans_Agy99           ADELRIVDGAGAPVAPGAEGELLVRGPYTINGYFCADRDNERCFDPAGFY
MSMEG_4516|M.smegmatis_MC2_155      DDEIRIVDEVGNEVPPGAEGELLVRGPYTLNGYFNAEAANERSFSPDGFY
MAB_2247c|M.abscessus_ATCC_199      ADEVRIVDEDGADVPAGETGELLVRGPYTLNGYYRADADNMRSFTVDGFY
MLBr_02661|M.leprae_Br4923          GVQIRIVGSDGQPLPPDTVGEVWLRGSTVVRGYLGDPAITAANFT-HGWL
                                      ::*:*.  *  : ..  **: :**. .. **      .   *   *: 

Mflv_2691|M.gilvum_PYR-GCK          RTGDRVRIFTDGPRAGYVEVTGRVKDVIHRGGETVSATDLEDHLHTHPSV
Mvan_3850|M.vanbaalenii_PYR-1       RTGDRVRIFADGPRAGYVEVVGRIKDVIHRGGETVSATDLEDHLHTHPAI
TH_2907|M.thermoresistible__bu      RTGDRVRIFADGPRAGHVEVTGRVKDVIHRGGETVSATDLEDHLLTHPAI
Rv2384|M.tuberculosis_H37Rv         RSGDLVRRRDD----GNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAI
Mb2405|M.bovis_AF2122/97            RSGDLVRRRDD----GNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAI
MAV_2008|M.avium_104                RSGDLVRVRDD----GYLVVTGRVKDVICRGGETISAADLEEQMLSHPAI
MMAR_3698|M.marinum_M               RSGDLVRLRDD----GYLQVTGRVKDVICRCGETISAQDLEEQLLSHPAI
MUL_3641|M.ulcerans_Agy99           RSGDLVRLRDD----GYLQVTGRVKDVICRCGETISAQDLEEQLLSHPAI
MSMEG_4516|M.smegmatis_MC2_155      RSGDRVRRFADGPLAGYLEVTGRIKDVIVRGGENVSALDLEEHLLTHPSV
MAB_2247c|M.abscessus_ATCC_199      RSGDRVRALPG----GYLEVTGRIKDVILRGGESIAALDLESHLQTHPAV
MLBr_02661|M.leprae_Br4923          RTGDLGSLSVT----GDLRIRGRIKELINRSGEKISPERVEGVLASHHNV
                                    *:**           * : : **:*::* * **.::.  :*  : :*  :

Mflv_2691|M.gilvum_PYR-GCK          YAAAAVALPDEYLGEKICAAVVFTGPP---LTLADLNAFLDERGASTHAR
Mvan_3850|M.vanbaalenii_PYR-1       YAAAAVALPDEYLGEKICAAVVFRGKP---ITLAELNAFLDERGASKHAR
TH_2907|M.thermoresistible__bu      YAAAAVPLPDEFLGEKICAAVVFRGAP---VSLTELNGYLDERGVATHAR
Rv2384|M.tuberculosis_H37Rv         FSAAAVGLPDQYLGEKICAAVVFAGAP---ITLAELNGYLDRRGVAAHTR
Mb2405|M.bovis_AF2122/97            FSAAAVGLPDQYLGEKICAAVVFAGAP---ITLAELNGYLDRRGVAAHTR
MAV_2008|M.avium_104                FSAAAVPLPDPYLGEKICAAVVFEGPA---LSLAELNGYLDERGVAAHAR
MMAR_3698|M.marinum_M               RSAAAVPLPDPDMGELICAAIVFAGPPQTPQTLSGLNDYLEQRGVAAHIR
MUL_3641|M.ulcerans_Agy99           RSAAAVPLPDPDMGELICAAIVFAGPPQTPQTLSGLNDYLEQRGVAAHIR
MSMEG_4516|M.smegmatis_MC2_155      WAAAAVALPDEFLGEKICAVVVFNGPP---VSLAELHAHLEQRGVAAHSR
MAB_2247c|M.abscessus_ATCC_199      YAAAAVGLPDQYLGEIVCAAIVFKGKP---VAAAELNQHLQARGAATHSR
MLBr_02661|M.leprae_Br4923          MEVAVFGDPDKVYGETVTAVIVPREVIAP--TPSELAVFCRDR-LAAFEV
                                      .*..  **   ** : *.:*         : : *  .   *  : .  

Mflv_2691|M.gilvum_PYR-GCK          PDVLVPVPSLPTTAVGKVDKKALVAQLTANS---------
Mvan_3850|M.vanbaalenii_PYR-1       PDVLMPVRSLPTTAVGKVDKKQLGAQLTS-----------
TH_2907|M.thermoresistible__bu      PDVLVALPSLPMTAVGKVDKKKVVEQVLSQ----------
Rv2384|M.tuberculosis_H37Rv         PDQLVAMPALPTTPIGKIDKRAIVRQLGIATGPVTTQRCH
Mb2405|M.bovis_AF2122/97            PDQLVAMPALPTTPIGKIDKRAIVRQLGIATGPVTTQRCH
MAV_2008|M.avium_104                PDVLAAMPSLPTTPIGKIDKKAIANQVSARNRRP------
MMAR_3698|M.marinum_M               IDRLVAMPSLPTTPVGKIDKKAIASQILTTTAT-------
MUL_3641|M.ulcerans_Agy99           IDRLVAMPSLPTTPVGKIDKKAIASQILTTTAT-------
MSMEG_4516|M.smegmatis_MC2_155      PDALVPMPSLPTTAVGKIDKKAIVRQLGG-----------
MAB_2247c|M.abscessus_ATCC_199      VDKLVAVSALPLTAVGKIDKRALLASLTG-----------
MLBr_02661|M.leprae_Br4923          PTRFQEASALPHTAKGSLDRRAVAEQFAHRG---------
                                       :    :** *. *.:*:: :  ..