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M. tuberculosis H37Rv Rv0051 (-)

annotation: PROBABLE CONSERVED TRANSMEMBRANE PROTEIN
coordinates: 55696 - 57378
length: 560

VTGALSQSSNISPLPLAADLRSADNRDCPSRTDVLGAALANVVGGPVGRHALIGRTRLMTPLRVMFAIAL
VFLALGWSTKAACLQSTGTGPGDQRVANWDNQRAYYQLCYSDTVPLYGAELLSQGKFPYKSSWIETDSNG
TPQLRYDGQIAVRYMEYPVLTGIYQYLSMAIAKTYTALSKVAPLPVVAEVVMFFNVAAFGLALAWLTTVW
ATSGLAGRRIWDAALVAASPLVIFQIFTNFDALATGLATSGLLAWARRRPVLAGVLIGLGSAAKLYPLLF
LYPLLLLGIRAGRLNALARTMAAAAATWLLVNLPVMLLFPRGWSEFFRLNTRRGDDMDSLYNVVKSFTGW
RGFDPTLGFWEPPLVLNTVVTLLFVLCCAAIAYIALTAPHRPRVAQLTFLTVASFLLVNKVWSPQFSLWL
VPLAVLALPHRRILLAWMTIDALVWVPRMYYLYGNPSRSLPEQWFTTTVLLRDIAVMVLCGLVVWQIYRP
GRDLVRTGGPGALPACGGVDDPVGGVFANAADAPPGRLPSWLRPRLGDEHARERTPDAGRDRTFSGQHRA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0051--100% (560)PROBABLE CONSERVED TRANSMEMBRANE PROTEIN
M. tuberculosis H37RvRv2181-4e-0725.34% (367) integral membrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0052-0.0100.00% (560) transmembrane protein
M. gilvum PYR-GCKMflv_0872-0.075.62% (525) hypothetical protein Mflv_0872
M. leprae Br4923MLBr_02687-0.078.46% (534) hypothetical protein MLBr_02687
M. abscessus ATCC 19977MAB_4900c-0.069.79% (533) hypothetical protein MAB_4900c
M. marinum MMMAR_0070-0.079.42% (554) hypothetical protein MMAR_0070
M. avium 104MAV_0072-0.082.58% (534) hypothetical protein MAV_0072
M. smegmatis MC2 155MSMEG_6899-0.070.49% (549) hypothetical protein MSMEG_6899
M. thermoresistible (build 8)TH_2091-0.076.46% (480) PROBABLE CONSERVED TRANSMEMBRANE PROTEIN
M. ulcerans Agy99MUL_0069-0.080.34% (534) hypothetical protein MUL_0069
M. vanbaalenii PYR-1Mvan_6035-0.074.21% (535) hypothetical protein Mvan_6035

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0872|M.gilvum_PYR-GCK          -------------MTSPSPLETDLRSLDSRDMPSRTDTLGAALSGTIGGP
Mvan_6035|M.vanbaalenii_PYR-1       MTAEPDSQAPPAGLDSPAPPAEDRRSLDTRDLPSRTDTIGAALSETIGGP
MSMEG_6899|M.smegmatis_MC2_155      ------MTGDQPGGVSPAPLAPNRASADDRDLPSRNDPMSSALSQVIGGP
TH_2091|M.thermoresistible__bu      --------------------------------------------------
Rv0051|M.tuberculosis_H37Rv         ----MTGALSQSSNISPLPLAADLRSADNRDCPSRTDVLGAALANVVGGP
Mb0052|M.bovis_AF2122/97            ----MTGALSQSSNISPLPLAADLRSADNRDCPSRTDVLGAALANVVGGP
MMAR_0070|M.marinum_M               ----MTDARTQRCATSPEPLARDLRSADYRDFPSRTDVLGSALAGVIGGP
MUL_0069|M.ulcerans_Agy99           ----MTDARTPRCATSPEPLARDLRSADYRDFPSRTDVLGSALAGGIGGP
MLBr_02687|M.leprae_Br4923          ----MINAQTHSTTISPRPLAADRQSADNRDCPSRTDYLGAALADAIGGP
MAV_0072|M.avium_104                ----MTGAAEPSTTISPGPLAADRRSADNRDCPSRNDFLGAAFAEVIGGP
MAB_4900c|M.abscessus_ATCC_199      --------MPTESTVSPEPLADDLRSADDRDFPSRTDALGAELSEVVGGP
                                                                                      

Mflv_0872|M.gilvum_PYR-GCK          VGRHALIGRTRFMTPLRVMLIIALVFLALGYSTKAACLQTTGTGTADQRV
Mvan_6035|M.vanbaalenii_PYR-1       VGRHALIGRTRFLTPLRVMMIIALVFLALGYSTKAACLQTTGTGAADQRV
MSMEG_6899|M.smegmatis_MC2_155      VGRHALIGRARFMTPLRAILLIAVVFLALGYSTKAACLQTTGTGTAGQRV
TH_2091|M.thermoresistible__bu      ------------------MLALALVFLALGYSTKAACLQTTGTGTADQRV
Rv0051|M.tuberculosis_H37Rv         VGRHALIGRTRLMTPLRVMFAIALVFLALGWSTKAACLQSTGTGPGDQRV
Mb0052|M.bovis_AF2122/97            VGRHALIGRTRLMTPLRVMFAIALVFLALGWSTKAACLQSTGTGPGDQRV
MMAR_0070|M.marinum_M               VGRHALIGRARFMTPVRVMFLMALVFLALGWSTKAACLQSTGTGPGDERV
MUL_0069|M.ulcerans_Agy99           VGRHALIGRARFMTPVRVMFLMALVFLALGWSTKAACLQTTGTGPGDERV
MLBr_02687|M.leprae_Br4923          VGCHALIGRSWLMTPLRVMFLIGLVFLALGWSTKAACLQTTGTGPGGQRV
MAV_0072|M.avium_104                VGRHALIGRARIMTPLRVMFLIALVFLALGWSTKAACLQSTGTGTGDQRV
MAB_4900c|M.abscessus_ATCC_199      LGRHALVGRQPFWTPLRVVFVIALGFLILGWTSKAPCLQQSGTGNGAQRV
                                                      :: :.: ** **:::**.*** :*** . :**

Mflv_0872|M.gilvum_PYR-GCK          GNWENQRAYYQLCYSDTVPLYTAELLNLGKFPYKSSWVETDAEGRPRVQY
Mvan_6035|M.vanbaalenii_PYR-1       GNWENQRAYYQLCYSDTVPLYTAELLNLGKFPYKSSWLETDAEGKPRAQY
MSMEG_6899|M.smegmatis_MC2_155      ANWENNRAYYELCYSDTVPLYTAELLNLGKFPYKSSWIEKDSSGKPRVQY
TH_2091|M.thermoresistible__bu      ADWSNQRAYYQLCYSDTVPLYTAELLDEGRFPYKSSWVETDSTGTPHITH
Rv0051|M.tuberculosis_H37Rv         ANWDNQRAYYQLCYSDTVPLYGAELLSQGKFPYKSSWIETDSNGTPQLRY
Mb0052|M.bovis_AF2122/97            ANWDNQRAYYQLCYSDTVPLYGAELLSQGKFPYKSSWIETDSNGTPQLRY
MMAR_0070|M.marinum_M               ANWDNQRAYYELCYSDTVPLYGAELLNQGKFPYKSSWIETNGEGTPQIQY
MUL_0069|M.ulcerans_Agy99           ANWDNQRAYYELCYSDTVPLYGAELLNQGKFPYKSSWIETNGEGTPQIQY
MLBr_02687|M.leprae_Br4923          PNWDNQRAYYELCYSDIVPLYGTELLSQGKFPYKSSWIETDSSGTPRTRY
MAV_0072|M.avium_104                ANWDNQRAYYELCYSDTVPLYGAELLSQGKFPYKSSWIETDSTGAQQIRY
MAB_4900c|M.abscessus_ATCC_199      ANWDNNRAYYQLCYSDTVPLYGAELLNQGRFPYKSSWLETDSGGHQKIQY
                                     :*.*:****:***** **** :***. *:*******:*.:. *  :  :

Mflv_0872|M.gilvum_PYR-GCK          DGEPAVRYMEYPVLTGLYQYLSMTVAKTYTALTKVVSIPVIAEVVMFFNI
Mvan_6035|M.vanbaalenii_PYR-1       DGEPAVRYMEYPVLTGIYQYLSMSLAKTYTALTKLVSVPVIAEVVMFFNI
MSMEG_6899|M.smegmatis_MC2_155      DGSPAIRYMEYPVITGIYQYVAMSLAKTYTALTKLVAIPIVAEVVMFFNI
TH_2091|M.thermoresistible__bu      DGRLAVRYMEYPVLTGLYQYVSMALAKTYTAATKLVSVPIVAEVVMFFNI
Rv0051|M.tuberculosis_H37Rv         DGQIAVRYMEYPVLTGIYQYLSMAIAKTYTALSKVAPLPVVAEVVMFFNV
Mb0052|M.bovis_AF2122/97            DGQIAVRYMEYPVLTGIYQYLSMAIAKTYTALSKVAPLPVVAEVVMFFNV
MMAR_0070|M.marinum_M               DGRIAVRYMEYPVLTGVYQYLSMALAKTYTALSKVAPLPVIAEVVMFFNA
MUL_0069|M.ulcerans_Agy99           DGRIAVRYMEYPVLTGVYQYLSMALAKTYTALSKVAPLPVIAEVVMFFNA
MLBr_02687|M.leprae_Br4923          DGRLAVRYMEYPVLTGIYQYVSMAVAKSYTALSEPVSLPAVAEVVMFFDV
MAV_0072|M.avium_104                DGQPAVRYMEYPVLTGMYQYVSMALAKTYTALSKLAPLPVVAEVVMFFNI
MAB_4900c|M.abscessus_ATCC_199      DGTPAVRYMEYPVVTGVYQYTAMALAKTYTQASDVLGLPIVAEVVMFFNI
                                    **  *:*******:**:*** :*::**:**  :.   :* :*******: 

Mflv_0872|M.gilvum_PYR-GCK          AALGLALAWLTTLWATAMLAGPRRIWDAALIAASPIVIFQIFTNFDALAT
Mvan_6035|M.vanbaalenii_PYR-1       AALGLALAWLTTLWATAMLAGPRRIWDAALLAASPLVIFQIFTNFDALAT
MSMEG_6899|M.smegmatis_MC2_155      AAFGLALAWLATIWATSRMAG-RRVWDAALVAASPIVIFQIFTNFDALAT
TH_2091|M.thermoresistible__bu      AAFGLALAWLATVWATARLAG-RRIWDAALVAASPILIFQIFTNFDALAV
Rv0051|M.tuberculosis_H37Rv         AAFGLALAWLTTVWATSGLAG-RRIWDAALVAASPLVIFQIFTNFDALAT
Mb0052|M.bovis_AF2122/97            AAFGLALAWLTTVWATSGLAG-RRIWDAALVAASPLVIFQIFTNFDALAT
MMAR_0070|M.marinum_M               AALGLALAWLATVWATAGLAG-RRIWDAALVAASPLVIFQIFTNFDALAT
MUL_0069|M.ulcerans_Agy99           AALGLALAWLATVWATAGLAG-RRIWDAALVAASPLVIFQIFTNFDALAT
MLBr_02687|M.leprae_Br4923          VAFGLALAWLATIWATAGLAG-LRIWDAALVAASPLVIFQVFTNFDALAI
MAV_0072|M.avium_104                AAFGLALAWLATVWASAGLAG-RRIWDAALVAGSPLLIFQIFTNFDALAT
MAB_4900c|M.abscessus_ATCC_199      VAFGLALAWLVTIWASAGLSPHTRPWDVVMIAASPIVIFQIFTNFDALAT
                                    .*:*******.*:**:: ::   * **..::*.**::***:******** 

Mflv_0872|M.gilvum_PYR-GCK          AFAACGMLAWARRRPVLAGVLIGLGVAAKLYPLLLLIPLVLLAVRTGRVR
Mvan_6035|M.vanbaalenii_PYR-1       AFAAGALLAWARRRPTLAGVLIGLGVAAKLYPLLLLVPLTLLAVRTGRLR
MSMEG_6899|M.smegmatis_MC2_155      AAAAGAMLAWSRRKPVVAGALIGLGVAAKLYPLLLLIPLVLLAVRTGRMR
TH_2091|M.thermoresistible__bu      ALATGALLAWARRRPVLAGLLIGLGVAAKLYPLLLLGPLLVLGIRAGRLR
Rv0051|M.tuberculosis_H37Rv         GLATSGLLAWARRRPVLAGVLIGLGSAAKLYPLLFLYPLLLLGIRAGRLN
Mb0052|M.bovis_AF2122/97            GLATSGLLAWARRRPVLAGVLIGLGSAAKLYPLLFLYPLLLLGIRAGRLN
MMAR_0070|M.marinum_M               AFAMGGLLAWARRKPWLSGVLIGLGAAAKLYPLLFLGVLAVLGIRSGRLG
MUL_0069|M.ulcerans_Agy99           AFAMGGLLAWARRKPWLSGVLIGLGAAAKLYPLLFLGVLAVLGIRSGRLG
MLBr_02687|M.leprae_Br4923          AFATGGLLAWSRCRPISAGVLIGLGAAAKLYPLLFLVPLFVLGVRTGRLG
MAV_0072|M.avium_104                AFAMAGLLAWARRRPVLAGVLIGLGAAAKLYPLLFLGPMLVLGIRTGRLG
MAB_4900c|M.abscessus_ATCC_199      AFSMTALWAWARKKPWLAGVLIGLGVAAKLYPVLLLLPLLLVSLRSGKVH
                                    . :  .: **:* :*  :* ***** ******:*:*  : ::.:*:*:: 

Mflv_0872|M.gilvum_PYR-GCK          EAGKTVVAAVVAWLAVNLPIMVLFPRGWSEFFRLNTRRGDDMDSIYNVVK
Mvan_6035|M.vanbaalenii_PYR-1       EAGKTAAAAVLAWVVVNLPIMVLFPRGWSEFFRLNTRRGDDMDSIYNVVK
MSMEG_6899|M.smegmatis_MC2_155      DVGKTALTAVATWLVVNLPIMVLFPRGWSEFFRLNTRRGDDMDSIYNVVK
TH_2091|M.thermoresistible__bu      EVGKTAAAAAVSWLVVNLPIMVLYPRGWSEFFRLNARRGDDMDSIYNVVK
Rv0051|M.tuberculosis_H37Rv         ALARTMAAAAATWLLVNLPVMLLFPRGWSEFFRLNTRRGDDMDSLYNVVK
Mb0052|M.bovis_AF2122/97            ALARTMAAAAATWLLVNLPVMLLFPRGWSEFFRLNTRRGDDMDSLYNVVK
MMAR_0070|M.marinum_M               GVLRAALATAATWLMVNLPVMVLYPRGWSEFFRLNTRRGEDMDSLYNVIK
MUL_0069|M.ulcerans_Agy99           GVLRATLPTAATWLMVNLPVMVLYPRGWSEFFRLNTRRGEDMDSLYNVIK
MLBr_02687|M.leprae_Br4923          GVACAAVTAATTWLLVNLPVLLLFPRGWSEFFRFNTRRGDDMDSLYNVVK
MAV_0072|M.avium_104                AWARTAVVAVATWLLVNLPVLVFFPRGWSEFFRLNTRRAEDMDSLYNVVK
MAB_4900c|M.abscessus_ATCC_199      EFSKTAAGAAASWVLVNMPVATLFPRGWGEFFRLNTRRGDDMDSLYNVFK
                                        :   :. :*: **:*:  ::****.****:*:**.:****:***.*

Mflv_0872|M.gilvum_PYR-GCK          SFTGWGGFDPDLGFWEPPVVLNTVTAALFAACLIAIAYIVLTATRRPRVA
Mvan_6035|M.vanbaalenii_PYR-1       SFTGWRGFDPELGFWEPPVVLNTVTAALFAACCIVIGYIVLTAERRPRVA
MSMEG_6899|M.smegmatis_MC2_155      SFTGWRGFDPGLGFWEPPTTLNTVTAILFAACCIAIGYITLTAPQRPRLA
TH_2091|M.thermoresistible__bu      SFTGWRGFDPDLGFWEPPTVLNVVSAVLFAACCLAIAVIALTAPQRPRLA
Rv0051|M.tuberculosis_H37Rv         SFTGWRGFDPTLGFWEPPLVLNTVVTLLFVLCCAAIAYIALTAPHRPRVA
Mb0052|M.bovis_AF2122/97            SFTGWRGFDPTLGFWEPPLVLNTVVTLLFVLCCAAIAYIALTAPHRPRVA
MMAR_0070|M.marinum_M               SFTGWRGFDPSLGFWEPPVVLNTVVTVLFGLACAAIVYIALTAPRRPRLA
MUL_0069|M.ulcerans_Agy99           SFTGWRGFDPSLGFWEPPVVLNTVVTALFGLACAAIVYIALTAPRRPRLA
MLBr_02687|M.leprae_Br4923          SLTGWRGFDTKLGFCELPLVLNTVVTVLFALCCAAVAYIALTAAQRPRVV
MAV_0072|M.avium_104                SFTGWRGFDPKLGFWQPPTVLNTVVAVLFVTCCAAIAFIALTAPRRPRAA
MAB_4900c|M.abscessus_ATCC_199      SFTGWQGFDGPLGFWEPPVILNAVSAVLFGLCCLGIGYVALTAPRRPRVA
                                    *:*** ***  *** : *  **.* : **  .   :  :.*** :*** .

Mflv_0872|M.gilvum_PYR-GCK          QIAFLVVAAFLLTNKVWSPQFSLWLVPLAVLALPHRRILLAWMTVDMLVW
Mvan_6035|M.vanbaalenii_PYR-1       QIAFLVVAAFLLTNKVWSPQFSLWLVPLAVLALPHRRILLAWMTVDMLVW
MSMEG_6899|M.smegmatis_MC2_155      QLAFLVVAAFLLTNKVWSPQFSLWLVPLAVLALPHRRILLAWMTIDALVW
TH_2091|M.thermoresistible__bu      QLAFLVVAVFLLTNKVWSPQFSLWLVPLAVLALPHRRILLAWMTIDALVW
Rv0051|M.tuberculosis_H37Rv         QLTFLTVASFLLVNKVWSPQFSLWLVPLAVLALPHRRILLAWMTIDALVW
Mb0052|M.bovis_AF2122/97            QLTFLTVASFLLVNKVWSPQFSLWLVPLAVLALPHRRILLAWMTIDALVW
MMAR_0070|M.marinum_M               QVAFLVVAVFLLTNKVWSPQFSLWLVPLAVLALPHRRVLLAWMTIDALVW
MUL_0069|M.ulcerans_Agy99           QVAFLVVAAFLLTNKVWSPQFSLWLVPLAVLALPHRRVLLAWMTIDALVW
MLBr_02687|M.leprae_Br4923          QLAFLLVAVFLLTNKVWSPQFSLWLVPLAVLALPHRRVLLAWMTIDALVW
MAV_0072|M.avium_104                QLVFLVVAAFLLTNKVWSPQFSLWLVPLAVLALPHRRVLLAWMTVDALVW
MAB_4900c|M.abscessus_ATCC_199      QLAFLVVAVFLLTNKVWSPQFSLWLVPLAVVALPHRRILLAWMTVDALVW
                                    *:.** ** ***.*****************:******:******:* ***

Mflv_0872|M.gilvum_PYR-GCK          VPRMLYLFGEQRMGLPEQAFTATVLLRDIAVITLCALVIRQIYRPELDLV
Mvan_6035|M.vanbaalenii_PYR-1       VPRMLYLFGEQKMGLPEQAFTATVLLRDLAVVGLCALVIREIYRPGLDLV
MSMEG_6899|M.smegmatis_MC2_155      VPRMLYLYGESNKGLPEQFFTTTVLLRDIAVIALCALVIRQIYRPELDLV
TH_2091|M.thermoresistible__bu      VPRMLYLYGEQNRGLPEQWFTATVLLRDIAVILLCALVIRQIYRPQQDLV
Rv0051|M.tuberculosis_H37Rv         VPRMYYLYGNPSRSLPEQWFTTTVLLRDIAVMVLCGLVVWQIYRPGRDLV
Mb0052|M.bovis_AF2122/97            VPRMYYLYGNPSRSLPEQWFTTTVLLRDIAVMVLCGLVVWQIYRPGRDLV
MMAR_0070|M.marinum_M               VPRMYYLYGNASRSLPEQWFTTTVLLRDIAVMALCALVIRQIYRPEEDLV
MUL_0069|M.ulcerans_Agy99           VPRMYYLYDNASRSLPEQWFTTTVLLRDIAVMALCALVIRQIYRPEEDLV
MLBr_02687|M.leprae_Br4923          VPRMYYLYGNPSRSLPEQWFTATVLLRDIAVVALCALVIRQIYRPDEDPV
MAV_0072|M.avium_104                VPRMYYLYGNPNRSLPEQVFTTTVLLRDIAVITLCALVIRQIYRPDEDLV
MAB_4900c|M.abscessus_ATCC_199      VPRMYYLLGIENKGLPEQWFTGTVLVRDLAVIGLCALVLRQIYHPGEDLV
                                    **** ** .    .**** ** ***:**:**: **.**: :**:*  * *

Mflv_0872|M.gilvum_PYR-GCK          R-HG--------GVDDPAGGVFDRAIDAPPRWLPDWLRPRP---------
Mvan_6035|M.vanbaalenii_PYR-1       R-QG--------GVDDPAGGVFDGAPDAPPRWLPDWLRPRPLVNSARQAT
MSMEG_6899|M.smegmatis_MC2_155      RWHG--------RIDDPTGGIYDRAPDSPPKWLPDRLRPTASRVRAERAS
TH_2091|M.thermoresistible__bu      RWDG--------RIDDPSGGVFDRAPDNPPRRLPDWLRPSTRR-------
Rv0051|M.tuberculosis_H37Rv         RTGGPGALPACGGVDDPVGGVFANAADAPPGRLPSWLRPRLGDEHARERT
Mb0052|M.bovis_AF2122/97            RTGGPGALPACGGVDDPVGGVFANAADAPPGRLPSWLRPRLGDEHARERT
MMAR_0070|M.marinum_M               RWDG--------RIDDPAGGTFDRAADAPPGWLPGWLRP-VHSRR---VT
MUL_0069|M.ulcerans_Agy99           RWDG--------RIDDPAGGTFDRAADAPPGWLPGWLRP-VHSRR---VT
MLBr_02687|M.leprae_Br4923          RLGG--------RVDDPAGGPFDRAPYAPPSWLPDWLHP-AGMRRVVTLA
MAV_0072|M.avium_104                RWGG--------RVDDPAGGPFNRAPDAPPGWLPDWLRP-AGSRR----G
MAB_4900c|M.abscessus_ATCC_199      RAGD----------DDPAGGPCDGVADAPPGWLPAWLRPRKPAPH----I
                                    *  .          *** **    .   **  **  *:*           

Mflv_0872|M.gilvum_PYR-GCK          -------SSPTSLAPAGP----------
Mvan_6035|M.vanbaalenii_PYR-1       ARVASRARSAGDFADQGTSL--------
MSMEG_6899|M.smegmatis_MC2_155      AAGISDQTRPQRTVDDRLA---------
TH_2091|M.thermoresistible__bu      ---IGVERAAPEPVPAA-----------
Rv0051|M.tuberculosis_H37Rv         PDAGRDRTFSGQHRA-------------
Mb0052|M.bovis_AF2122/97            PDAGRDRTFSGQHRA-------------
MMAR_0070|M.marinum_M               VAAAPEPVPVGGR---------------
MUL_0069|M.ulcerans_Agy99           VAAAPEPVTVGDR---------------
MLBr_02687|M.leprae_Br4923          ASSVTETELAAAATPSGPMHHPHAPSSI
MAV_0072|M.avium_104                QAAEPEPALAGAT---------------
MAB_4900c|M.abscessus_ATCC_199      ARAHSVGSSASLTRK-------------