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VTGALSQSSNISPLPLAADLRSADNRDCPSRTDVLGAALANVVGGPVGRHALIGRTRLMTPLRVMFAIAL VFLALGWSTKAACLQSTGTGPGDQRVANWDNQRAYYQLCYSDTVPLYGAELLSQGKFPYKSSWIETDSNG TPQLRYDGQIAVRYMEYPVLTGIYQYLSMAIAKTYTALSKVAPLPVVAEVVMFFNVAAFGLALAWLTTVW ATSGLAGRRIWDAALVAASPLVIFQIFTNFDALATGLATSGLLAWARRRPVLAGVLIGLGSAAKLYPLLF LYPLLLLGIRAGRLNALARTMAAAAATWLLVNLPVMLLFPRGWSEFFRLNTRRGDDMDSLYNVVKSFTGW RGFDPTLGFWEPPLVLNTVVTLLFVLCCAAIAYIALTAPHRPRVAQLTFLTVASFLLVNKVWSPQFSLWL VPLAVLALPHRRILLAWMTIDALVWVPRMYYLYGNPSRSLPEQWFTTTVLLRDIAVMVLCGLVVWQIYRP GRDLVRTGGPGALPACGGVDDPVGGVFANAADAPPGRLPSWLRPRLGDEHARERTPDAGRDRTFSGQHRA
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv0051 | - | - | 100% (560) | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN |
M. tuberculosis H37Rv | Rv2181 | - | 4e-07 | 25.34% (367) | integral membrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0052 | - | 0.0 | 100.00% (560) | transmembrane protein |
M. gilvum PYR-GCK | Mflv_0872 | - | 0.0 | 75.62% (525) | hypothetical protein Mflv_0872 |
M. leprae Br4923 | MLBr_02687 | - | 0.0 | 78.46% (534) | hypothetical protein MLBr_02687 |
M. abscessus ATCC 19977 | MAB_4900c | - | 0.0 | 69.79% (533) | hypothetical protein MAB_4900c |
M. marinum M | MMAR_0070 | - | 0.0 | 79.42% (554) | hypothetical protein MMAR_0070 |
M. avium 104 | MAV_0072 | - | 0.0 | 82.58% (534) | hypothetical protein MAV_0072 |
M. smegmatis MC2 155 | MSMEG_6899 | - | 0.0 | 70.49% (549) | hypothetical protein MSMEG_6899 |
M. thermoresistible (build 8) | TH_2091 | - | 0.0 | 76.46% (480) | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN |
M. ulcerans Agy99 | MUL_0069 | - | 0.0 | 80.34% (534) | hypothetical protein MUL_0069 |
M. vanbaalenii PYR-1 | Mvan_6035 | - | 0.0 | 74.21% (535) | hypothetical protein Mvan_6035 |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_0872|M.gilvum_PYR-GCK -------------MTSPSPLETDLRSLDSRDMPSRTDTLGAALSGTIGGP Mvan_6035|M.vanbaalenii_PYR-1 MTAEPDSQAPPAGLDSPAPPAEDRRSLDTRDLPSRTDTIGAALSETIGGP MSMEG_6899|M.smegmatis_MC2_155 ------MTGDQPGGVSPAPLAPNRASADDRDLPSRNDPMSSALSQVIGGP TH_2091|M.thermoresistible__bu -------------------------------------------------- Rv0051|M.tuberculosis_H37Rv ----MTGALSQSSNISPLPLAADLRSADNRDCPSRTDVLGAALANVVGGP Mb0052|M.bovis_AF2122/97 ----MTGALSQSSNISPLPLAADLRSADNRDCPSRTDVLGAALANVVGGP MMAR_0070|M.marinum_M ----MTDARTQRCATSPEPLARDLRSADYRDFPSRTDVLGSALAGVIGGP MUL_0069|M.ulcerans_Agy99 ----MTDARTPRCATSPEPLARDLRSADYRDFPSRTDVLGSALAGGIGGP MLBr_02687|M.leprae_Br4923 ----MINAQTHSTTISPRPLAADRQSADNRDCPSRTDYLGAALADAIGGP MAV_0072|M.avium_104 ----MTGAAEPSTTISPGPLAADRRSADNRDCPSRNDFLGAAFAEVIGGP MAB_4900c|M.abscessus_ATCC_199 --------MPTESTVSPEPLADDLRSADDRDFPSRTDALGAELSEVVGGP Mflv_0872|M.gilvum_PYR-GCK VGRHALIGRTRFMTPLRVMLIIALVFLALGYSTKAACLQTTGTGTADQRV Mvan_6035|M.vanbaalenii_PYR-1 VGRHALIGRTRFLTPLRVMMIIALVFLALGYSTKAACLQTTGTGAADQRV MSMEG_6899|M.smegmatis_MC2_155 VGRHALIGRARFMTPLRAILLIAVVFLALGYSTKAACLQTTGTGTAGQRV TH_2091|M.thermoresistible__bu ------------------MLALALVFLALGYSTKAACLQTTGTGTADQRV Rv0051|M.tuberculosis_H37Rv VGRHALIGRTRLMTPLRVMFAIALVFLALGWSTKAACLQSTGTGPGDQRV Mb0052|M.bovis_AF2122/97 VGRHALIGRTRLMTPLRVMFAIALVFLALGWSTKAACLQSTGTGPGDQRV MMAR_0070|M.marinum_M VGRHALIGRARFMTPVRVMFLMALVFLALGWSTKAACLQSTGTGPGDERV MUL_0069|M.ulcerans_Agy99 VGRHALIGRARFMTPVRVMFLMALVFLALGWSTKAACLQTTGTGPGDERV MLBr_02687|M.leprae_Br4923 VGCHALIGRSWLMTPLRVMFLIGLVFLALGWSTKAACLQTTGTGPGGQRV MAV_0072|M.avium_104 VGRHALIGRARIMTPLRVMFLIALVFLALGWSTKAACLQSTGTGTGDQRV MAB_4900c|M.abscessus_ATCC_199 LGRHALVGRQPFWTPLRVVFVIALGFLILGWTSKAPCLQQSGTGNGAQRV :: :.: ** **:::**.*** :*** . :** Mflv_0872|M.gilvum_PYR-GCK GNWENQRAYYQLCYSDTVPLYTAELLNLGKFPYKSSWVETDAEGRPRVQY Mvan_6035|M.vanbaalenii_PYR-1 GNWENQRAYYQLCYSDTVPLYTAELLNLGKFPYKSSWLETDAEGKPRAQY MSMEG_6899|M.smegmatis_MC2_155 ANWENNRAYYELCYSDTVPLYTAELLNLGKFPYKSSWIEKDSSGKPRVQY TH_2091|M.thermoresistible__bu ADWSNQRAYYQLCYSDTVPLYTAELLDEGRFPYKSSWVETDSTGTPHITH Rv0051|M.tuberculosis_H37Rv ANWDNQRAYYQLCYSDTVPLYGAELLSQGKFPYKSSWIETDSNGTPQLRY Mb0052|M.bovis_AF2122/97 ANWDNQRAYYQLCYSDTVPLYGAELLSQGKFPYKSSWIETDSNGTPQLRY MMAR_0070|M.marinum_M ANWDNQRAYYELCYSDTVPLYGAELLNQGKFPYKSSWIETNGEGTPQIQY MUL_0069|M.ulcerans_Agy99 ANWDNQRAYYELCYSDTVPLYGAELLNQGKFPYKSSWIETNGEGTPQIQY MLBr_02687|M.leprae_Br4923 PNWDNQRAYYELCYSDIVPLYGTELLSQGKFPYKSSWIETDSSGTPRTRY MAV_0072|M.avium_104 ANWDNQRAYYELCYSDTVPLYGAELLSQGKFPYKSSWIETDSTGAQQIRY MAB_4900c|M.abscessus_ATCC_199 ANWDNNRAYYQLCYSDTVPLYGAELLNQGRFPYKSSWLETDSGGHQKIQY :*.*:****:***** **** :***. *:*******:*.:. * : : Mflv_0872|M.gilvum_PYR-GCK DGEPAVRYMEYPVLTGLYQYLSMTVAKTYTALTKVVSIPVIAEVVMFFNI Mvan_6035|M.vanbaalenii_PYR-1 DGEPAVRYMEYPVLTGIYQYLSMSLAKTYTALTKLVSVPVIAEVVMFFNI MSMEG_6899|M.smegmatis_MC2_155 DGSPAIRYMEYPVITGIYQYVAMSLAKTYTALTKLVAIPIVAEVVMFFNI TH_2091|M.thermoresistible__bu DGRLAVRYMEYPVLTGLYQYVSMALAKTYTAATKLVSVPIVAEVVMFFNI Rv0051|M.tuberculosis_H37Rv DGQIAVRYMEYPVLTGIYQYLSMAIAKTYTALSKVAPLPVVAEVVMFFNV Mb0052|M.bovis_AF2122/97 DGQIAVRYMEYPVLTGIYQYLSMAIAKTYTALSKVAPLPVVAEVVMFFNV MMAR_0070|M.marinum_M DGRIAVRYMEYPVLTGVYQYLSMALAKTYTALSKVAPLPVIAEVVMFFNA MUL_0069|M.ulcerans_Agy99 DGRIAVRYMEYPVLTGVYQYLSMALAKTYTALSKVAPLPVIAEVVMFFNA MLBr_02687|M.leprae_Br4923 DGRLAVRYMEYPVLTGIYQYVSMAVAKSYTALSEPVSLPAVAEVVMFFDV MAV_0072|M.avium_104 DGQPAVRYMEYPVLTGMYQYVSMALAKTYTALSKLAPLPVVAEVVMFFNI MAB_4900c|M.abscessus_ATCC_199 DGTPAVRYMEYPVVTGVYQYTAMALAKTYTQASDVLGLPIVAEVVMFFNI ** *:*******:**:*** :*::**:** :. :* :*******: Mflv_0872|M.gilvum_PYR-GCK AALGLALAWLTTLWATAMLAGPRRIWDAALIAASPIVIFQIFTNFDALAT Mvan_6035|M.vanbaalenii_PYR-1 AALGLALAWLTTLWATAMLAGPRRIWDAALLAASPLVIFQIFTNFDALAT MSMEG_6899|M.smegmatis_MC2_155 AAFGLALAWLATIWATSRMAG-RRVWDAALVAASPIVIFQIFTNFDALAT TH_2091|M.thermoresistible__bu AAFGLALAWLATVWATARLAG-RRIWDAALVAASPILIFQIFTNFDALAV Rv0051|M.tuberculosis_H37Rv AAFGLALAWLTTVWATSGLAG-RRIWDAALVAASPLVIFQIFTNFDALAT Mb0052|M.bovis_AF2122/97 AAFGLALAWLTTVWATSGLAG-RRIWDAALVAASPLVIFQIFTNFDALAT MMAR_0070|M.marinum_M AALGLALAWLATVWATAGLAG-RRIWDAALVAASPLVIFQIFTNFDALAT MUL_0069|M.ulcerans_Agy99 AALGLALAWLATVWATAGLAG-RRIWDAALVAASPLVIFQIFTNFDALAT MLBr_02687|M.leprae_Br4923 VAFGLALAWLATIWATAGLAG-LRIWDAALVAASPLVIFQVFTNFDALAI MAV_0072|M.avium_104 AAFGLALAWLATVWASAGLAG-RRIWDAALVAGSPLLIFQIFTNFDALAT MAB_4900c|M.abscessus_ATCC_199 VAFGLALAWLVTIWASAGLSPHTRPWDVVMIAASPIVIFQIFTNFDALAT .*:*******.*:**:: :: * **..::*.**::***:******** Mflv_0872|M.gilvum_PYR-GCK AFAACGMLAWARRRPVLAGVLIGLGVAAKLYPLLLLIPLVLLAVRTGRVR Mvan_6035|M.vanbaalenii_PYR-1 AFAAGALLAWARRRPTLAGVLIGLGVAAKLYPLLLLVPLTLLAVRTGRLR MSMEG_6899|M.smegmatis_MC2_155 AAAAGAMLAWSRRKPVVAGALIGLGVAAKLYPLLLLIPLVLLAVRTGRMR TH_2091|M.thermoresistible__bu ALATGALLAWARRRPVLAGLLIGLGVAAKLYPLLLLGPLLVLGIRAGRLR Rv0051|M.tuberculosis_H37Rv GLATSGLLAWARRRPVLAGVLIGLGSAAKLYPLLFLYPLLLLGIRAGRLN Mb0052|M.bovis_AF2122/97 GLATSGLLAWARRRPVLAGVLIGLGSAAKLYPLLFLYPLLLLGIRAGRLN MMAR_0070|M.marinum_M AFAMGGLLAWARRKPWLSGVLIGLGAAAKLYPLLFLGVLAVLGIRSGRLG MUL_0069|M.ulcerans_Agy99 AFAMGGLLAWARRKPWLSGVLIGLGAAAKLYPLLFLGVLAVLGIRSGRLG MLBr_02687|M.leprae_Br4923 AFATGGLLAWSRCRPISAGVLIGLGAAAKLYPLLFLVPLFVLGVRTGRLG MAV_0072|M.avium_104 AFAMAGLLAWARRRPVLAGVLIGLGAAAKLYPLLFLGPMLVLGIRTGRLG MAB_4900c|M.abscessus_ATCC_199 AFSMTALWAWARKKPWLAGVLIGLGVAAKLYPVLLLLPLLLVSLRSGKVH . : .: **:* :* :* ***** ******:*:* : ::.:*:*:: Mflv_0872|M.gilvum_PYR-GCK EAGKTVVAAVVAWLAVNLPIMVLFPRGWSEFFRLNTRRGDDMDSIYNVVK Mvan_6035|M.vanbaalenii_PYR-1 EAGKTAAAAVLAWVVVNLPIMVLFPRGWSEFFRLNTRRGDDMDSIYNVVK MSMEG_6899|M.smegmatis_MC2_155 DVGKTALTAVATWLVVNLPIMVLFPRGWSEFFRLNTRRGDDMDSIYNVVK TH_2091|M.thermoresistible__bu EVGKTAAAAAVSWLVVNLPIMVLYPRGWSEFFRLNARRGDDMDSIYNVVK Rv0051|M.tuberculosis_H37Rv ALARTMAAAAATWLLVNLPVMLLFPRGWSEFFRLNTRRGDDMDSLYNVVK Mb0052|M.bovis_AF2122/97 ALARTMAAAAATWLLVNLPVMLLFPRGWSEFFRLNTRRGDDMDSLYNVVK MMAR_0070|M.marinum_M GVLRAALATAATWLMVNLPVMVLYPRGWSEFFRLNTRRGEDMDSLYNVIK MUL_0069|M.ulcerans_Agy99 GVLRATLPTAATWLMVNLPVMVLYPRGWSEFFRLNTRRGEDMDSLYNVIK MLBr_02687|M.leprae_Br4923 GVACAAVTAATTWLLVNLPVLLLFPRGWSEFFRFNTRRGDDMDSLYNVVK MAV_0072|M.avium_104 AWARTAVVAVATWLLVNLPVLVFFPRGWSEFFRLNTRRAEDMDSLYNVVK MAB_4900c|M.abscessus_ATCC_199 EFSKTAAGAAASWVLVNMPVATLFPRGWGEFFRLNTRRGDDMDSLYNVFK : :. :*: **:*: ::****.****:*:**.:****:***.* Mflv_0872|M.gilvum_PYR-GCK SFTGWGGFDPDLGFWEPPVVLNTVTAALFAACLIAIAYIVLTATRRPRVA Mvan_6035|M.vanbaalenii_PYR-1 SFTGWRGFDPELGFWEPPVVLNTVTAALFAACCIVIGYIVLTAERRPRVA MSMEG_6899|M.smegmatis_MC2_155 SFTGWRGFDPGLGFWEPPTTLNTVTAILFAACCIAIGYITLTAPQRPRLA TH_2091|M.thermoresistible__bu SFTGWRGFDPDLGFWEPPTVLNVVSAVLFAACCLAIAVIALTAPQRPRLA Rv0051|M.tuberculosis_H37Rv SFTGWRGFDPTLGFWEPPLVLNTVVTLLFVLCCAAIAYIALTAPHRPRVA Mb0052|M.bovis_AF2122/97 SFTGWRGFDPTLGFWEPPLVLNTVVTLLFVLCCAAIAYIALTAPHRPRVA MMAR_0070|M.marinum_M SFTGWRGFDPSLGFWEPPVVLNTVVTVLFGLACAAIVYIALTAPRRPRLA MUL_0069|M.ulcerans_Agy99 SFTGWRGFDPSLGFWEPPVVLNTVVTALFGLACAAIVYIALTAPRRPRLA MLBr_02687|M.leprae_Br4923 SLTGWRGFDTKLGFCELPLVLNTVVTVLFALCCAAVAYIALTAAQRPRVV MAV_0072|M.avium_104 SFTGWRGFDPKLGFWQPPTVLNTVVAVLFVTCCAAIAFIALTAPRRPRAA MAB_4900c|M.abscessus_ATCC_199 SFTGWQGFDGPLGFWEPPVILNAVSAVLFGLCCLGIGYVALTAPRRPRVA *:*** *** *** : * **.* : ** . : :.*** :*** . Mflv_0872|M.gilvum_PYR-GCK QIAFLVVAAFLLTNKVWSPQFSLWLVPLAVLALPHRRILLAWMTVDMLVW Mvan_6035|M.vanbaalenii_PYR-1 QIAFLVVAAFLLTNKVWSPQFSLWLVPLAVLALPHRRILLAWMTVDMLVW MSMEG_6899|M.smegmatis_MC2_155 QLAFLVVAAFLLTNKVWSPQFSLWLVPLAVLALPHRRILLAWMTIDALVW TH_2091|M.thermoresistible__bu QLAFLVVAVFLLTNKVWSPQFSLWLVPLAVLALPHRRILLAWMTIDALVW Rv0051|M.tuberculosis_H37Rv QLTFLTVASFLLVNKVWSPQFSLWLVPLAVLALPHRRILLAWMTIDALVW Mb0052|M.bovis_AF2122/97 QLTFLTVASFLLVNKVWSPQFSLWLVPLAVLALPHRRILLAWMTIDALVW MMAR_0070|M.marinum_M QVAFLVVAVFLLTNKVWSPQFSLWLVPLAVLALPHRRVLLAWMTIDALVW MUL_0069|M.ulcerans_Agy99 QVAFLVVAAFLLTNKVWSPQFSLWLVPLAVLALPHRRVLLAWMTIDALVW MLBr_02687|M.leprae_Br4923 QLAFLLVAVFLLTNKVWSPQFSLWLVPLAVLALPHRRVLLAWMTIDALVW MAV_0072|M.avium_104 QLVFLVVAAFLLTNKVWSPQFSLWLVPLAVLALPHRRVLLAWMTVDALVW MAB_4900c|M.abscessus_ATCC_199 QLAFLVVAVFLLTNKVWSPQFSLWLVPLAVVALPHRRILLAWMTVDALVW *:.** ** ***.*****************:******:******:* *** Mflv_0872|M.gilvum_PYR-GCK VPRMLYLFGEQRMGLPEQAFTATVLLRDIAVITLCALVIRQIYRPELDLV Mvan_6035|M.vanbaalenii_PYR-1 VPRMLYLFGEQKMGLPEQAFTATVLLRDLAVVGLCALVIREIYRPGLDLV MSMEG_6899|M.smegmatis_MC2_155 VPRMLYLYGESNKGLPEQFFTTTVLLRDIAVIALCALVIRQIYRPELDLV TH_2091|M.thermoresistible__bu VPRMLYLYGEQNRGLPEQWFTATVLLRDIAVILLCALVIRQIYRPQQDLV Rv0051|M.tuberculosis_H37Rv VPRMYYLYGNPSRSLPEQWFTTTVLLRDIAVMVLCGLVVWQIYRPGRDLV Mb0052|M.bovis_AF2122/97 VPRMYYLYGNPSRSLPEQWFTTTVLLRDIAVMVLCGLVVWQIYRPGRDLV MMAR_0070|M.marinum_M VPRMYYLYGNASRSLPEQWFTTTVLLRDIAVMALCALVIRQIYRPEEDLV MUL_0069|M.ulcerans_Agy99 VPRMYYLYDNASRSLPEQWFTTTVLLRDIAVMALCALVIRQIYRPEEDLV MLBr_02687|M.leprae_Br4923 VPRMYYLYGNPSRSLPEQWFTATVLLRDIAVVALCALVIRQIYRPDEDPV MAV_0072|M.avium_104 VPRMYYLYGNPNRSLPEQVFTTTVLLRDIAVITLCALVIRQIYRPDEDLV MAB_4900c|M.abscessus_ATCC_199 VPRMYYLLGIENKGLPEQWFTGTVLVRDLAVIGLCALVLRQIYHPGEDLV **** ** . .**** ** ***:**:**: **.**: :**:* * * Mflv_0872|M.gilvum_PYR-GCK R-HG--------GVDDPAGGVFDRAIDAPPRWLPDWLRPRP--------- Mvan_6035|M.vanbaalenii_PYR-1 R-QG--------GVDDPAGGVFDGAPDAPPRWLPDWLRPRPLVNSARQAT MSMEG_6899|M.smegmatis_MC2_155 RWHG--------RIDDPTGGIYDRAPDSPPKWLPDRLRPTASRVRAERAS TH_2091|M.thermoresistible__bu RWDG--------RIDDPSGGVFDRAPDNPPRRLPDWLRPSTRR------- Rv0051|M.tuberculosis_H37Rv RTGGPGALPACGGVDDPVGGVFANAADAPPGRLPSWLRPRLGDEHARERT Mb0052|M.bovis_AF2122/97 RTGGPGALPACGGVDDPVGGVFANAADAPPGRLPSWLRPRLGDEHARERT MMAR_0070|M.marinum_M RWDG--------RIDDPAGGTFDRAADAPPGWLPGWLRP-VHSRR---VT MUL_0069|M.ulcerans_Agy99 RWDG--------RIDDPAGGTFDRAADAPPGWLPGWLRP-VHSRR---VT MLBr_02687|M.leprae_Br4923 RLGG--------RVDDPAGGPFDRAPYAPPSWLPDWLHP-AGMRRVVTLA MAV_0072|M.avium_104 RWGG--------RVDDPAGGPFNRAPDAPPGWLPDWLRP-AGSRR----G MAB_4900c|M.abscessus_ATCC_199 RAGD----------DDPAGGPCDGVADAPPGWLPAWLRPRKPAPH----I * . *** ** . ** ** *:* Mflv_0872|M.gilvum_PYR-GCK -------SSPTSLAPAGP---------- Mvan_6035|M.vanbaalenii_PYR-1 ARVASRARSAGDFADQGTSL-------- MSMEG_6899|M.smegmatis_MC2_155 AAGISDQTRPQRTVDDRLA--------- TH_2091|M.thermoresistible__bu ---IGVERAAPEPVPAA----------- Rv0051|M.tuberculosis_H37Rv PDAGRDRTFSGQHRA------------- Mb0052|M.bovis_AF2122/97 PDAGRDRTFSGQHRA------------- MMAR_0070|M.marinum_M VAAAPEPVPVGGR--------------- MUL_0069|M.ulcerans_Agy99 VAAAPEPVTVGDR--------------- MLBr_02687|M.leprae_Br4923 ASSVTETELAAAATPSGPMHHPHAPSSI MAV_0072|M.avium_104 QAAEPEPALAGAT--------------- MAB_4900c|M.abscessus_ATCC_199 ARAHSVGSSASLTRK-------------