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MSLSVRRPPAARAAAIVEAESWFLKRGLPSVLTMRGRCRRLWPRSAPMLAAWAVVEGCLMAVFFVTDGGE VFISATPTTAQWVILALLAVALPLASLVGWLVSQISSGRGQAAVATMAVAFAAASDVIESGPIQLLRTAV VVGLVLLQTGCGVGSVLGWAVRMTLEHLATVGTLAVRALPIVLLTALVFFNTYVWLMAANINGERLTLAM VFLLAIAGAFVVSKTVERVRPLLRSTTVMPQGSQSLAGTPFATMGDPSPGFPLTRAERLNVVFLLAASQL VEILVVASVGAAIYLVLGMIILTPPLLREWTHYDSMTTTVLGMTFPAPDSLIRMCLFLGALTFMYISARA VDDAEYRAMFLDPLIDDLHTALLARNRYRNNVVTAPCAGVDAGHVDD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2113 | - | - | 100% (397) | Probable integral membrane protein |
| M. tuberculosis H37Rv | Rv3671c | - | 1e-05 | 28.31% (219) | membrane-associated serine protease |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2137 | - | 0.0 | 99.50% (397) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_3074 | - | 4e-85 | 46.65% (373) | hypothetical protein Mflv_3074 |
| M. leprae Br4923 | MLBr_02298 | - | 8e-06 | 26.64% (214) | putative membrane-associated serine protease |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_3089 | - | 1e-121 | 56.54% (382) | integral membrane protein |
| M. avium 104 | MAV_0459 | - | 5e-05 | 25.12% (211) | serine protease |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_0962 | - | 1e-05 | 27.37% (274) | serine protease |
| M. ulcerans Agy99 | MUL_2335 | - | 7e-88 | 57.14% (294) | integral membrane protein |
| M. vanbaalenii PYR-1 | Mvan_3452 | - | 1e-86 | 47.27% (366) | hypothetical protein Mvan_3452 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3074|M.gilvum_PYR-GCK --------MTPTSVQRLAAERWFLDRGLPAVLRPGVLVQRVWTRSAPALA
Mvan_3452|M.vanbaalenii_PYR-1 --------MTPKTEQRRAAERWFLQRGLPAVLRPGVLVQRVWTRSAPALA
Rv2113|M.tuberculosis_H37Rv MSLSVRRPPAARAAAIVEAESWFLKRGLPSVLTMRGRCRRLWPRSAPMLA
Mb2137|M.bovis_AF2122/97 MSLSVRRPPAARAAAIVEAESWFLKRGLPSVLTMRGRCRRLWPRSAPMLA
MMAR_3089|M.marinum_M MNPSPHRAPARRDPSSAAAESWFLERGLPAVLTRRARWRRLWSRSAPVLA
MUL_2335|M.ulcerans_Agy99 -----------------------------------------MSRHEPFPA
MLBr_02298|M.leprae_Br4923 --------------MSSMTLSEWLDIAVLAVAFIAAISGWRSGALGSLLS
MAV_0459|M.avium_104 ------------MNLNSMTPSQWLDVAVLAVAFIAAISGWRSGALGSLLS
TH_0962|M.thermoresistible__bu -----------------MTAAQWLDFAILAVALIAAISGWRSGAVGSLMS
. :
Mflv_3074|M.gilvum_PYR-GCK ALAVAMAFSILVVGVTGKHTIDIDGTPTRTEWFVLGVVVVVLPTAAFVGW
Mvan_3452|M.vanbaalenii_PYR-1 ALAVMMAFSTLVVAVTGEHTIAIDGTPTRTEWFIIGVVLVVLPTAALVGW
Rv2113|M.tuberculosis_H37Rv AWAVVEGCLMAVFFVTDGGEVFISATPTTAQWVILALLAVALPLASLVGW
Mb2137|M.bovis_AF2122/97 AWAVVEGCLMAVFFVTDGGEVFISATPTTAQWVILALLAVALPLASLVGW
MMAR_3089|M.marinum_M AYATLHCWTLPILLITHGDEVVIDGQPTPREWVLVTLVAIAPVLITFVGW
MUL_2335|M.ulcerans_Agy99 PRS---------------------GTPRPVECRGGKLVS---------GT
MLBr_02298|M.leprae_Br4923 LIGVLFGAMAGVLLVP--HVVSHISAPRAKLFAALFLILALVVIGEVVGV
MAV_0459|M.avium_104 FVGVLLGAIAGVLLAP--HLVSHIAAPRAKLFAALFLILALVVIGEVAGV
TH_0962|M.thermoresistible__bu FLGVVLGAVAGVLLAP--HVVTYIDGARTRLFATLFLILALVVIGEIAGV
. . :: *
Mflv_3074|M.gilvum_PYR-GCK LVSRSDDVRLRAVVSTASVGVGILGALYGGPSPRVWADLVAEAVIVALIL
Mvan_3452|M.vanbaalenii_PYR-1 LVSRTDDLRLRGAVSTTSLAVAALGGIYAGPSAHVFVDMVTEIVLIVLIF
Rv2113|M.tuberculosis_H37Rv LVSQISSGRGQAAVATMAVAFAAASDVIESGP----IQLLRTAVVVGLVL
Mb2137|M.bovis_AF2122/97 LVSQISSGRGQAAVATMAVAFAAASDVIESGP----IQLLRTAVVVGLVL
MMAR_3089|M.marinum_M LVSRLSDSRMRSVAATVAVSLVAIVLIVETSV----SHLPDAALAAVMVL
MUL_2335|M.ulcerans_Agy99 GLARGAD-QAGPLAATVAVSLVAIVLIVETSV----SHLPDAALAAVMVL
MLBr_02298|M.leprae_Br4923 VLGRAVRSANRSRTVRLVDSVIGVGVQLIVVLTAAWLLATPLTQSKEQPE
MAV_0459|M.avium_104 VLGRAVRGAIRSRSIRTVDSVIGVGVQLVVVLTAAWLLATPLTQSKDQPE
TH_0962|M.thermoresistible__bu VLGRAARSALRSGPVRALDSVTGVAMQLVAVLLAAWLLATPLASTSGQPA
:.: ..
Mflv_3074|M.gilvum_PYR-GCK LGTASGGGAILGWAVRMMLGNLASVGNLLLRALPVMLLTVLVFFNGPVWT
Mvan_3452|M.vanbaalenii_PYR-1 VCTATGVGAILGWAVRMTLANLASVGNLLLGALPVMLLTVLVFFNGPVWT
Rv2113|M.tuberculosis_H37Rv LQTGCGVGSVLGWAVRMTLEHLATVGTLAVRALPIVLLTALVFFNTYVWL
Mb2137|M.bovis_AF2122/97 LQTGCGVGSVLGWAVRMTLEHLATVGTLAVRALPIVLLTALVFFNTYVWL
MMAR_3089|M.marinum_M LLTGSGIGSVTGWSVRMTLSHLATIGALAVRALPVVLLTTLVFFNSNIWL
MUL_2335|M.ulcerans_Agy99 LLTGSGIGSVTGWSVRMTLSHLATIGALAVRALPVVLLTTLVFFNSNIWL
MLBr_02298|M.leprae_Br4923 LASAVRGSRALASVNEVAPPWLKTVPKRLSALLNTSGLPAVLEPFSRTPV
MAV_0459|M.avium_104 LAAAVRGSRVLAKVNEVAPPWLKTVPKRLSALLNTSGLPAVLEPFSRTPV
TH_0962|M.thermoresistible__bu VAAAVSDSRLLSEVDKVAPEWLRSVPQRISALLDDSGLPDVLEPFGRTPI
: :. . . .: * :: * *. ::
Mflv_3074|M.gilvum_PYR-GCK MAATVHRPRLWFALVFLMTIAVSFLLSTMMAGVRPILLPDAKAEQDAAAL
Mvan_3452|M.vanbaalenii_PYR-1 MASTITRPRLWVALLFLMLIAVTFLVSSTLSLVGPILSPDAKRPEDAAQL
Rv2113|M.tuberculosis_H37Rv MAANINGERLTLAMVFLLAIAGAFVVSKTVERVRPLLRSTTVMPQGSQSL
Mb2137|M.bovis_AF2122/97 MAANINGERLPLAMVFLLAIAGAFVVSKTVERVRPLLRSTTVMPQGSQSL
MMAR_3089|M.marinum_M MASTISAERLALAIAFLVGIASVFVISTTAERVKPMLQAPTVQPKNCQEL
MUL_2335|M.ulcerans_Agy99 MASTISAERLALAIAFLVGIASVFVISTTAERVKPMLQAPTVQPKNCQEL
MLBr_02298|M.leprae_Br4923 LPVASPDPALVDNPVVLATQPSVVKIRSVAPSCQKVLEGTGFVVSLDRVM
MAV_0459|M.avium_104 IPVASPDPELASNPVVQATAPSVVKVRSLAPSCQKVLEGSGFVIAPDRVM
TH_0962|M.thermoresistible__bu AAVDEPDPALAQDTVVGLTAPSVVKIRGVAEVCRKVLEGSGFVIAPNRVM
. * . . . : :* :
Mflv_3074|M.gilvum_PYR-GCK RGTPFETMPDRPRRVDLSRSERLNVGFVLALSQIVQVLTVSIVTGLLFFA
Mvan_3452|M.vanbaalenii_PYR-1 DGTPFETMPDRPRRVKLSKAERLNVVFVLAMSQVVQVLTVSIVTGLLFFV
Rv2113|M.tuberculosis_H37Rv AGTPFATMGDPSPGFPLTRAERLNVVFLLAASQLVEILVVASVGAAIYLV
Mb2137|M.bovis_AF2122/97 AGTPFATMGDPSPGFPLTRAERLNVVFLLAALQLVEILVVASVGAAIYLV
MMAR_3089|M.marinum_M ADTPFAAMPDPPSSRPLTRAERANVVFVLTAHQLVQIMVVAMLTATIYVI
MUL_2335|M.ulcerans_Agy99 ADTPFAAMPDPPSSRPLTRAERANVVFVLTAHQLVQIMVVAMLTATIYVI
MLBr_02298|M.leprae_Br4923 TNAHVVAGSDGVQVYASGNPFDATVVSYDPSVDIAILAVPHLPPAPLRFD
MAV_0459|M.avium_104 TNAHVVAGSNSVQIYASGNPLDATVVSYDPSVDIAILAVPNLPPPPLPFA
TH_0962|M.thermoresistible__bu SNAHVVAGADQVTIDADGQEYPATVVSYDPDIDISILDVPDLPLRPLQFV
.: . : : . .* . :: : . : .
Mflv_3074|M.gilvum_PYR-GCK FGLILISPELLAALTANG-----SPDGWFLGMTLPVPDALIQVSMFLTAL
Mvan_3452|M.vanbaalenii_PYR-1 LGLILISPELLAALTNGG-----SSDGEFLGMTLPVPQALIHITMFLTAL
Rv2113|M.tuberculosis_H37Rv LGMIILTPPLLREWTHYD-----SMTTTVLGMTFPAPDSLIRMCLFLGAL
Mb2137|M.bovis_AF2122/97 LGMIILTPPLLREWTHYD-----SMTTTVLGMTFPAPDSLIRMCLFLGAL
MMAR_3089|M.marinum_M LGLIVLSPALLQEWSHNV-----SSNATVLGLTVPVPDSLIHLCLFIGAL
MUL_2335|M.ulcerans_Agy99 LELIVLSPALLQEWSHNV-----SSNATVLGLTVPVPDSLIHLCLFIGAL
MLBr_02298|M.leprae_Br4923 DTKAKPGTNVVMLGYPGGGNFTATSARIRQAIKLTGPDIYRGLAPVTRDV
MAV_0459|M.avium_104 QTEAKTGASVVVLGYPGGGNFTATPARIRELIKLSGPDIYRDPAPVTRDV
TH_0962|M.thermoresistible__bu DHEAPPGTDAVAMGYPGGGDFVATPVRVRETITLKGPDIYQSKT-VTRSV
. : : :.. *: . :
Mflv_3074|M.gilvum_PYR-GCK TFMYLAARAVA--------DKEYRTQFLDPLIEDLRVTLVARDRYRTVTA
Mvan_3452|M.vanbaalenii_PYR-1 TFMYLAARTVG--------DKDYRAQFLDPLIEDLRFTLVARDRYRTLTA
Rv2113|M.tuberculosis_H37Rv TFMYISARAVD--------DAEYRAMFLDPLIDDLHTALLARNRYRNNVV
Mb2137|M.bovis_AF2122/97 TFMYISARAVD--------DAEYRAMFLDPLIDDLHTALLARNRYRNNVV
MMAR_3089|M.marinum_M TFMYISARAVG--------DAEYRATFVDPLIENLHITLIARGRYRANID
MUL_2335|M.ulcerans_Agy99 TFMYISARAVG--------DAEYRATFVDPLIENLHITLIAPGRYGANID
MLBr_02298|M.leprae_Br4923 YTIRATVEQGNSGGPLIDLNGRVLGVVFGAAVDDSETGFVLTAEEVSHRL
MAV_0459|M.avium_104 YTIRASVEQGNSGGPLIDLNGQVLGVVFGAAVDDPDTGFVLTADEVAGQL
TH_0962|M.thermoresistible__bu YTVRGSIKQGNSGGPMIDRSGKVLGVVFGAAVDDDDTGFVLTAKQVEHQI
: : . . .... ::: ::
Mflv_3074|M.gilvum_PYR-GCK DPPPGNTPS------------
Mvan_3452|M.vanbaalenii_PYR-1 NT-------------------
Rv2113|M.tuberculosis_H37Rv TAPCAGVDAGHVDD-------
Mb2137|M.bovis_AF2122/97 TAPCAGVDAGHVDD-------
MMAR_3089|M.marinum_M DT---DVDASPGGD-------
MUL_2335|M.ulcerans_Agy99 DT---DVDASPGGD-------
MLBr_02298|M.leprae_Br4923 TEIGETQEAVATGACVS----
MAV_0459|M.avium_104 AKIGET-KTVGTGSCVS----
TH_0962|M.thermoresistible__bu ARVGNT-EPVPTGQCVGAPAP