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M. thermoresistible (build 8) TH_0962 (-)

annotation: serine protease
coordinates: 1907016 - 1908218
length: 401

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0962--100% (401)serine protease
M. thermoresistible (build 8)TH_1677-2e-1831.61% (193) Trypsin
M. thermoresistible (build 8)TH_4473-2e-1030.05% (183) PUTATIVE peptidase S1 and S6, chymotrypsin/Hap

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3695c-1e-14162.63% (396) putative membrane-associated serine protease
M. gilvum PYR-GCKMflv_1376-1e-15870.03% (397) colicin V production protein
M. tuberculosis H37RvRv3671c-1e-14162.37% (396) membrane-associated serine protease
M. leprae Br4923MLBr_02298-1e-14062.97% (397) putative membrane-associated serine protease
M. abscessus ATCC 19977MAB_0421-1e-14764.74% (397) membrane-associated serine protease
M. marinum MMMAR_5159-1e-14764.65% (396) membrane-associated serine protease
M. avium 104MAV_0459-1e-14565.40% (396) serine protease
M. smegmatis MC2 155MSMEG_6183-1e-16573.05% (397) serine protease
M. ulcerans Agy99MUL_4245-1e-14764.39% (396) membrane-associated serine protease
M. vanbaalenii PYR-1Mvan_5430-1e-15769.77% (397) colicin V production protein

CLUSTAL 2.0.9 multiple sequence alignment


TH_0962|M.thermoresistible__bu      -----MTAAQWLDFAILAVALIAAISGWRSGAVGSLMSFLGVVLGAVAGV
MSMEG_6183|M.smegmatis_MC2_155      -----MTPSLWLDLAVVAIAFVAAISGWRSGALGSLMSFIGVVLGAVAGV
Mflv_1376|M.gilvum_PYR-GCK          -----MNSSQWLDIAILAVAMLAAVSGWRSGAPGSLMALVGVVLGAGAGI
Mvan_5430|M.vanbaalenii_PYR-1       -----MNSSQWLDISILALALIAAISGWRSGAPGSLLALVGVALGAAAGI
MAB_0421|M.abscessus_ATCC_1997      ---MNLNPSQWLDIGVIAVAFIAAVSGWRSGALGSLMSFVGVILGAVAGI
Mb3695c|M.bovis_AF2122/97           -----MTPSQWLDIAVLAVAFIAAISGWRAGALGSMLSFGGVLLGATAGV
Rv3671c|M.tuberculosis_H37Rv        -----MTPSQWLDIAVLAVAFIAAISGWRAGALGSMLSFGGVLLGATAGV
MMAR_5159|M.marinum_M               --MNSMTPSQWLDIAVLAVAFIAAVSGWRSGALGSMLSFAGVLLGAIAGV
MUL_4245|M.ulcerans_Agy99           --MNSMTPSQWLDIAVLAVAFIAAVSGWRSGALGSMLSFAGVLLGAIAGV
MAV_0459|M.avium_104                MNLNSMTPSQWLDVAVLAVAFIAAISGWRSGALGSLLSFVGVLLGAIAGV
MLBr_02298|M.leprae_Br4923          --MSSMTLSEWLDIAVLAVAFIAAISGWRSGALGSLLSLIGVLFGAMAGV
                                         :. : ***..::*:*::**:****:** **:::: ** :** **:

TH_0962|M.thermoresistible__bu      LLAPHVVTYIDGARTRLFATLFLILALVVIGEIAGVVLGRAARSALRSGP
MSMEG_6183|M.smegmatis_MC2_155      LLAPHVIPHVDGARTKLFVTLFLILALVVVGEIAGVVLGRAVRGTIRSGL
Mflv_1376|M.gilvum_PYR-GCK          LLAPHVVDHISGPRTKLFATLFLILVLVVIGEIAGVVLGRAVRGAIRNPG
Mvan_5430|M.vanbaalenii_PYR-1       LLAPHVVSHISGPRTKLFVTLFLILALVVIGEIAGVVLGRAVRGAIRSPG
MAB_0421|M.abscessus_ATCC_1997      MLAPHVVANIEGSRTKLFASLLLILVLVVIGEVAGVVLGRAMRGAIRNRV
Mb3695c|M.bovis_AF2122/97           LLAPHIVSQISAPRAKLFAALFLILALVVVGEVAGVVLGRAVRGAIRNRP
Rv3671c|M.tuberculosis_H37Rv        LLAPHIVSQISAPRAKLFAALFLILALVVVGEVAGVVLGRAVRGAIRNRP
MMAR_5159|M.marinum_M               LLAPHIVSHINAPRAKLFAALFLILGLVVVGEVAGVVLGRAVRGAIRNRP
MUL_4245|M.ulcerans_Agy99           LLAPHIVSHINAPRAKLFAALFLILGLVVVGEVAGVVLGRAVRGAIRNRP
MAV_0459|M.avium_104                LLAPHLVSHIAAPRAKLFAALFLILALVVIGEVAGVVLGRAVRGAIRSRS
MLBr_02298|M.leprae_Br4923          LLVPHVVSHISAPRAKLFAALFLILALVVIGEVVGVVLGRAVRSANRSRT
                                    :*.**::  : ..*::**.:*:*** ***:**:.******* *.: *.  

TH_0962|M.thermoresistible__bu      VRALDSVTGVAMQLVAVLLAAWLLATPLASTSGQPAVAAAVSDSRLLSEV
MSMEG_6183|M.smegmatis_MC2_155      FRAFDSVVGVSLMLVAVLVAAWLLGS-LLTSSDQPNLAAAVKGSRVLSEV
Mflv_1376|M.gilvum_PYR-GCK          LRIVDSVVGVALQLVLVLTAAWLLGTALVSSP-QPNLAAAVSGSRVIAEV
Mvan_5430|M.vanbaalenii_PYR-1       LRVADSVVGVALQLVLVLTAAWLLGTALVSSP-QPNLAAAVQGSKVIAEV
MAB_0421|M.abscessus_ATCC_1997      LRTGDSVVGVVLQVAAVLVAAWLLSIPMQSSN-QPNISAAARESKVLSQV
Mb3695c|M.bovis_AF2122/97           IRLIDSVIGVGVQLVVVLTAAWLLAMPLTQSKEQPELAAAVKGSRVLARV
Rv3671c|M.tuberculosis_H37Rv        IRLIDSVIGVGVQLVVVLTAAWLLAMPLTQSKEQPELAAAVKGSRVLARV
MMAR_5159|M.marinum_M               IRVIDSVIGVGVQLVVVLTAAWLLATPLTQSKDQPELAAAVRGSRVLAQV
MUL_4245|M.ulcerans_Agy99           IRVIDSVIGVGVQLVVVLTAAWLLATPLTQSKDQPELAAAVRGSRVLAQV
MAV_0459|M.avium_104                IRTVDSVIGVGVQLVVVLTAAWLLATPLTQSKDQPELAAAVRGSRVLAKV
MLBr_02298|M.leprae_Br4923          VRLVDSVIGVGVQLIVVLTAAWLLATPLTQSKEQPELASAVRGSRALASV
                                    .*  *** ** : :  ** *****.  :  :  ** :::*.  *: :: *

TH_0962|M.thermoresistible__bu      DKVAPEWLRSVPQRISALLDDSGLPDVLEPFGRTPIAAVDEPDPALAQDT
MSMEG_6183|M.smegmatis_MC2_155      DRVAPTWLRQVPTRLSGLLDTSGLPDVLEPFGRTPIVNVDAPDAALADDA
Mflv_1376|M.gilvum_PYR-GCK          DAVAPDWLRSVPDRMSSVWENAGLHDVLKPFGPTPVAAVDAPDPALATSP
Mvan_5430|M.vanbaalenii_PYR-1       DSVAPSWLRSVPNRLSALWETAGLHDVLKPFGPTPVAEIDPPDPSLATSP
MAB_0421|M.abscessus_ATCC_1997      DKYAPDQLRKVPNDLSKLLDTSGLPSVLQPFGKTPIAAVDAPDATLADGP
Mb3695c|M.bovis_AF2122/97           NEAAPTWLKTVPKRLSALLNTSGLPAVLEPFSRTPVIPVASPDPALVNNP
Rv3671c|M.tuberculosis_H37Rv        NEAAPTWLKTVPKRLSALLNTSGLPAVLEPFSRTPVIPVASPDPALVNNP
MMAR_5159|M.marinum_M               NEVAPTWLKTVPKRLSGLLNTSGLPAVLEPFSRTPVIPVASPDPALARNP
MUL_4245|M.ulcerans_Agy99           NAVAPTWLKTVPKRLSGLLNTSGLPAVLEPFSRTPVIPVASPDPALARNP
MAV_0459|M.avium_104                NEVAPPWLKTVPKRLSALLNTSGLPAVLEPFSRTPVIPVASPDPELASNP
MLBr_02298|M.leprae_Br4923          NEVAPPWLKTVPKRLSALLNTSGLPAVLEPFSRTPVLPVASPDPALVDNP
                                    :  **  *: **  :* : : :**  **:**. **:  :  **. *. ..

TH_0962|M.thermoresistible__bu      VVGLTAPSVVKIRGVAEVCRKVLEGSGFVIAPNRVMSNAHVVAGADQVTI
MSMEG_6183|M.smegmatis_MC2_155      VVAATRPSVVKIRGVAPSCQKVLEGSGFVVAPSRVMSNAHVVAGADSVTV
Mflv_1376|M.gilvum_PYR-GCK          VVNQTRSSVVKVKGVAQSCQKVLEGTGFVVAPNRVMSNAHVVAGSDTVTV
Mvan_5430|M.vanbaalenii_PYR-1       VVNTTRSSVVKVRGVAQSCQKVLEGTGFVVAPNRVMSNAHVVAGSDSVTV
MAB_0421|M.abscessus_ATCC_1997      VVRGSEPSVVKIKGIARSCQKSLEGTGFVIAPHRVMSNAHVVAGTNSVTV
Mb3695c|M.bovis_AF2122/97           VVAATEPSVVKIRSLAPRCQKVLEGTGFVISPDRVMTNAHVVAGSNNVTV
Rv3671c|M.tuberculosis_H37Rv        VVAATEPSVVKIRSLAPRCQKVLEGTGFVISPDRVMTNAHVVAGSNNVTV
MMAR_5159|M.marinum_M               VVEATAPSVLKIRSLAPSCQKVLEGSGFVIAPDRVMTNAHVVAGANSVQV
MUL_4245|M.ulcerans_Agy99           VVEATAPSVLKIRSLAPSCQKVLEGSGFVIAPDRVMTNAHVVAGANSVQV
MAV_0459|M.avium_104                VVQATAPSVVKVRSLAPSCQKVLEGSGFVIAPDRVMTNAHVVAGSNSVQI
MLBr_02298|M.leprae_Br4923          VVLATQPSVVKIRSVAPSCQKVLEGTGFVVSLDRVMTNAHVVAGSDGVQV
                                    **  : .**:*::.:*  *:* ***:***::  ***:*******:: * :

TH_0962|M.thermoresistible__bu      DADGQEYPATVVSYDPDIDISILDVPDLPLRPLQFVDHEAPPGTDAVAMG
MSMEG_6183|M.smegmatis_MC2_155      EVDGETYDAHVVSYDPDADISILDVPNLPSAPLAFAADPAPQGTDAVVMG
Mflv_1376|M.gilvum_PYR-GCK          EVDGQEYTAGVVSYDPNADISILDVPDLPSVPLQFVDALAQTGTDGIVLG
Mvan_5430|M.vanbaalenii_PYR-1       EVDGQTYDAGVVSYDPNADISILDVPNLPSAPLQFVDAEAQPGTDGIVMG
MAB_0421|M.abscessus_ATCC_1997      ESAGQTYDASVVSYDPNADISILAVPDMPAAPLVFASKPAKTGDDAIVLG
Mb3695c|M.bovis_AF2122/97           YAGDKPFEATVVSYDPSVDVAILAVPHLPPPPLVFAAEPAKTGADVVVLG
Rv3671c|M.tuberculosis_H37Rv        YAGDKPFEATVVSYDPSVDVAILAVPHLPPPPLVFAAEPAKTGADVVVLG
MMAR_5159|M.marinum_M               FASGKPLDATVVSYDPSVDIAILAVPGLPPPPLIFAEREAPTGTNVVVLG
MUL_4245|M.ulcerans_Agy99           FASGKPLDATVVSYDPSVDIAILAVPGLPPPPLIFAEREAPTGTNVVVLG
MAV_0459|M.avium_104                YASGNPLDATVVSYDPSVDIAILAVPNLPPPPLPFAQTEAKTGASVVVLG
MLBr_02298|M.leprae_Br4923          YASGNPFDATVVSYDPSVDIAILAVPHLPPAPLRFDDTKAKPGTNVVMLG
                                       .:   * ******. *::** ** :*  ** *    *  * . : :*

TH_0962|M.thermoresistible__bu      YPGGGDFVATPVRVRETITLKGPDIYQS-KTVTRSVYTVRGSIKQGNSGG
MSMEG_6183|M.smegmatis_MC2_155      YPGGGDFLATPARVREIIELNGPDIYRT-TTVTREVYTVRGTVRQGNSGG
Mflv_1376|M.gilvum_PYR-GCK          YPGGGDFTATPARVREVIELNGPDIYRS-TTVTREVYTIRGTVRQGNSGG
Mvan_5430|M.vanbaalenii_PYR-1       YPGGGEFTATPARVREVIELNGPDIYRS-TTVTREVYTIRGTVKQGNSGG
MAB_0421|M.abscessus_ATCC_1997      YPGGGDYKASPARVREIIELKGPDIYRS-ITVTREVYTVRGSVLQGNSGG
Mb3695c|M.bovis_AF2122/97           YPGGGNFTATPARIREAIRLSGPDIYGDPEPVTRDVYTIRADVEQGDSGG
Rv3671c|M.tuberculosis_H37Rv        YPGGGNFTATPARIREAIRLSGPDIYGDPEPVTRDVYTIRADVEQGDSGG
MMAR_5159|M.marinum_M               YPGGGNFTATPARIREAIRLSGPDIYRNPQPVTRDVYTIRANVEQGDSGG
MUL_4245|M.ulcerans_Agy99           YPGGGNFTATPARIREATRLSGPDIYRNLQPVTRDVYTIRANVEQGDSGG
MAV_0459|M.avium_104                YPGGGNFTATPARIRELIKLSGPDIYRDPAPVTRDVYTIRASVEQGNSGG
MLBr_02298|M.leprae_Br4923          YPGGGNFTATSARIRQAIKLTGPDIYRGLAPVTRDVYTIRATVEQGNSGG
                                    *****:: *:..*:*:   *.*****    .***.***:*. : **:***

TH_0962|M.thermoresistible__bu      PMIDRSGKVLGVVFGAAVDDDDTGFVLTAKQVEHQIARVGNTEP-VPTGQ
MSMEG_6183|M.smegmatis_MC2_155      PMINRAGKVLGVVFGAAVDDVDTGFVLTAKEVERQLAKIGNTER-VATGT
Mflv_1376|M.gilvum_PYR-GCK          PMVNRQGKVLGVVFGAAVDDIDTGFVLTADEVAAQMARVGNVDL-VPTGT
Mvan_5430|M.vanbaalenii_PYR-1       PMINRQGRVLGVVFGAAVDDVDTGFVLTADEVARQMAKVGNVER-VATGT
MAB_0421|M.abscessus_ATCC_1997      PLIDTEGRVLGVVFGAAIDDDDTGFALTAKQVKDQLAKADLADP-VATGS
Mb3695c|M.bovis_AF2122/97           PLIDLNGQVLGVVFGAAVDDAETGFVLTAGEVAGQLAKIGATQP-VGTGA
Rv3671c|M.tuberculosis_H37Rv        PLIDLNGQVLGVVFGAAIDDAETGFVLTAGEVAGQLAKIGATQP-VGTGA
MMAR_5159|M.marinum_M               PLIDLNGQVLGVVFGAAVDDPDTGFVLTSGEVASQLARIGATER-VATGS
MUL_4245|M.ulcerans_Agy99           PLIDLNGQVLGVVFGAAVDDPDTGFVLTSGEVASQLARIGATER-VATGS
MAV_0459|M.avium_104                PLIDLNGQVLGVVFGAAVDDPDTGFVLTADEVAGQLAKIGETKT-VGTGS
MLBr_02298|M.leprae_Br4923          PLIDLNGRVLGVVFGAAVDDSETGFVLTAEEVSHRLTEIGETQEAVATGA
                                    *:::  *:*********:** :***.**: :*  :::. . ..  * ** 

TH_0962|M.thermoresistible__bu      CVGAPAP--------------------
MSMEG_6183|M.smegmatis_MC2_155      CINS-----------------------
Mflv_1376|M.gilvum_PYR-GCK          CISSG----------------------
Mvan_5430|M.vanbaalenii_PYR-1       CISAG----------------------
MAB_0421|M.abscessus_ATCC_1997      CVSAAEANRPTEQPVNGPQSPVPGKAP
Mb3695c|M.bovis_AF2122/97           CVS------------------------
Rv3671c|M.tuberculosis_H37Rv        CVS------------------------
MMAR_5159|M.marinum_M               CVS------------------------
MUL_4245|M.ulcerans_Agy99           CVS------------------------
MAV_0459|M.avium_104                CVS------------------------
MLBr_02298|M.leprae_Br4923          CVS------------------------
                                    *:.