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M. smegmatis MC2 155 MSMEG_3618 (-)

annotation: alanine and proline-rich secreted protein apa
coordinates: 3680844 - 3681905
length: 353

YESDSMSHRRSGLSKKLTLAAVTGMTAVAVALPSVAHADPEPPPPPPGNTFLPAPPPADPNAPAPAPAPA
PAPAPAPAPALAPAPAPGAPAPAPAPAPAPADPNAPAPAPADPNAPAPAPAEEPPAPEPGRVDNAAGGFS
YVVPEGWQVSDATQLSYGQALLTKTVAEGAEPPNDTSVLLGRLDLKLFAGAEPDNNKAAVRLASDMGEFF
MPFPGTRVNQQTVQLNADGMPGVASYYEVKFTDANKPAGQIWAGVVGQPVAPGTPRGQRTPERWFVVWLG
TANNPIDKDAAVALANSIRPWAPPPPPPPAPADPADPNAAPPPPDPNAPPARPGVGVPVPVTDAPPEMMP
PA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_3618--100% (353)alanine and proline-rich secreted protein apa
M. smegmatis MC2 155MSMEG_0679-3e-1840.30% (134) hypothetical protein MSMEG_0679
M. smegmatis MC2 155MSMEG_5700-3e-1731.64% (373) secreted protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1891apa2e-9151.40% (358) hypothetical protein Mb1891
M. gilvum PYR-GCKMflv_3345-1e-13569.21% (367) fibronectin-attachment family protein
M. tuberculosis H37RvRv1860apa7e-9151.12% (358) hypothetical protein Rv1860
M. leprae Br4923MLBr_02055modD2e-6847.06% (323) putative cell surface protein (associated with virulence)
M. abscessus ATCC 19977MAB_2436-3e-7848.57% (350) hypothetical protein MAB_2436
M. marinum MMMAR_2737apa1e-10356.82% (352) alanine and proline rich secreted protein Apa
M. avium 104MAV_2859-3e-9451.90% (368) ModD protein
M. thermoresistible (build 8)TH_1368modD1e-10876.17% (256) ALANINE AND PROLINE RICH SECRETED PROTEIN APA (FIBRONECTIN
M. ulcerans Agy99MUL_3017apa7e-8951.56% (353) alanine and proline rich secreted protein Apa
M. vanbaalenii PYR-1Mvan_3075-1e-12865.75% (365) fibronectin-attachment family protein

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_3618|M.smegmatis_MC2_155      --MYESDSMSHRRSGLSKKLTLAAVTGMT----AVAVALPSVAHADPEPP
TH_1368|M.thermoresistible__bu      --------------------------------------------------
Mflv_3345|M.gilvum_PYR-GCK          MTMDQPNVFPHRRAGTPTSIRRSVVTGATTAALAAALALPGIANAQPAPT
Mvan_3075|M.vanbaalenii_PYR-1       --MDQPDMHAKRRKGLPTSFRRSALTGAT-AALTAVFTLPAVAYAQPAPP
Mb1891|M.bovis_AF2122/97            --MHQVDPNLTRRKGRLAALAIAAMASAS----LVTVAVPATANADPEPA
Rv1860|M.tuberculosis_H37Rv         --MHQVDPNLTRRKGRLAALAIAAMASAS----LVTVAVPATANADPEPA
MLBr_02055|M.leprae_Br4923          --MNQVDLDSTHRKGLWAILAIAVVASAS----AFTMPLPAAANADPAPL
MMAR_2737|M.marinum_M               --MHEVDPNKRRRHGLWTTLALAAVSSAS----VVSIALPATASADPAPA
MUL_3017|M.ulcerans_Agy99           --MHEVDPNKRRRHGLWTTLALAAVSSAS----VVSIALPATASADPAPA
MAV_2859|M.avium_104                --MDQVEATSTRRKGLWTTLAITTVSGAS----AVAIALPATSHADPEVP
MAB_2436|M.abscessus_ATCC_1997      --MQQPRATSAAKRTHRARVIAATIAVTSLSG-AGAYTLAATP-VDQAPA
                                                                                      

MSMEG_3618|M.smegmatis_MC2_155      P----PPPGNTFLPAPPPADPNAPAPAPAPAPAPAPAPAPALAPAPAPGA
TH_1368|M.thermoresistible__bu      --------------VPPPGQP-----------------------------
Mflv_3345|M.gilvum_PYR-GCK          PTPAPPPPAVGAPQAPAPDAPAAPAPAPPADPN----------------A
Mvan_3075|M.vanbaalenii_PYR-1       PSPAPPPAVEAPPVPPPPVDPNAPVPPPPVDPN----------------A
Mb1891|M.bovis_AF2122/97            PPVPTTAASPPSTAAAPPAPATPVAPPPPAAANT---------PNAQPGD
Rv1860|M.tuberculosis_H37Rv         PPVPTTAASPPSTAAAPPAPATPVAPPPPAAANT---------PNAQPGD
MLBr_02055|M.leprae_Br4923          P---------PSTATAAPSPAQEIITPLPGAPVS---------SEAQPGD
MMAR_2737|M.marinum_M               P--------APSTTAAP--PADPNAAPPPADPNA---------PPPPPAD
MUL_3017|M.ulcerans_Agy99           P--------APSTTAAP--PADPNAAPPPADP------------------
MAV_2859|M.avium_104                TPVPPSTATAPPAAPAPNGQPAPNAQPAPAAPAPNGQPAP---AAPAPND
MAB_2436|M.abscessus_ATCC_1997      TVRTANIHLVTTDAPPPPAPPATPAPGQPAPNPE---------TPTTVTT
                                                   ..   .                             

MSMEG_3618|M.smegmatis_MC2_155      PAPAPAPAP-------APADPNAPAPAPADPNAPAPAPAEE--PPAPEPG
TH_1368|M.thermoresistible__bu      -------------------------PAPADPNAPA--------EPAPEP-
Mflv_3345|M.gilvum_PYR-GCK          PAPAAPPAT-------PPADPNAPVPPPADPNAPAPAGPEAPAAPAPEPG
Mvan_3075|M.vanbaalenii_PYR-1       PVPPP-----------PPVDPNAPVPPPADPNAPVP--------PAPEPG
Mb1891|M.bovis_AF2122/97            PNAAP-----------PPADPNAPPPPVIAPNAPQP-------------V
Rv1860|M.tuberculosis_H37Rv         PNAAP-----------PPADPNAPPPPVIAPNAPQP-------------V
MLBr_02055|M.leprae_Br4923          PNA-------------PSLDPNAPYPLAVDPNAG----------------
MMAR_2737|M.marinum_M               PNAPPPPPADPNAPPPPPADPNAPPPPVVDPNAPEP-------------G
MUL_3017|M.ulcerans_Agy99           ---------------------NAPPPPVVDPNAPEP-------------G
MAV_2859|M.avium_104                PNAAPPPAG-APPNGAPPAPPNGAPPPPVDPNAPPPPPADP------NAG
MAB_2436|M.abscessus_ATCC_1997      PPPAP------------APGQPAPPTPPPAPGAPAD------------GG
                                                             .    *.*                 

MSMEG_3618|M.smegmatis_MC2_155      RVDNAAGGFSYVVPEGWQVSDATQLSYGQALLTKTV--AEGAE----PPN
TH_1368|M.thermoresistible__bu      RENNAAGGFSYVVPGGWQVSDATQLSYGQALLTKIP--PPGSQQ---PPN
Mflv_3345|M.gilvum_PYR-GCK          RVDNAAGGFSYVVPAGWKVSDATQLSYGQALLSKLP--PEGSPPDAQPPN
Mvan_3075|M.vanbaalenii_PYR-1       RIDNAAGGFSYVVPAGWEVSDSTQLSYGQALLTKLP--PEGAPPDAQPPN
Mb1891|M.bovis_AF2122/97            RIDNPVGGFSFALPAGWVESDAAHLDYGSALLSKTTGDPPFPGQPPPVAN
Rv1860|M.tuberculosis_H37Rv         RIDNPVGGFSFALPAGWVESDAAHFDYGSALLSKTTGDPPFPGQPPPVAN
MLBr_02055|M.leprae_Br4923          RITNAVGGFSFVLPAGWVESEASHLDYGSVLLSKAIEQPPVLGQPTVVAT
MMAR_2737|M.marinum_M               RVNNAVGGFSFVVPAGWVESDASHLDYGSALLSKMTGEPPMPGQAPPIAN
MUL_3017|M.ulcerans_Agy99           RVNNAVGGFSSVVPAGWVESDASHLDYGSALLSKMTGEPPMPGQAPPIAN
MAV_2859|M.avium_104                RIPNAVGGFSYVLPAGWVESDASHLDYGSALLSKVTGPPPMPDQPPPVAN
MAB_2436|M.abscessus_ATCC_1997      RVNNDQGGFSFVVPQGWVQSDARRLTYGSALLTNPA------------AP
                                    *  *  **** .:* **  *:: :: **..**::              . 

MSMEG_3618|M.smegmatis_MC2_155      DTSVLLGRLDLKLFAGAEPDNNKAAVRLASDMGEFFMPFPGTRVNQQTVQ
TH_1368|M.thermoresistible__bu      DTSILLGRLDLKLFAGAEPDNTKAANRLASDMGEFFMPYPGTRINQETVP
Mflv_3345|M.gilvum_PYR-GCK          DTSVLLGRLDLKLFAGAETDNTKAAQRLASDMGEFFMPFPGTRVNQQVVP
Mvan_3075|M.vanbaalenii_PYR-1       DTSVLLGRLDLKLFAGAENDNTKAAQRLASDMGEFFMPFPGTRVNQQVVP
Mb1891|M.bovis_AF2122/97            DTRIVLGRLDQKLYASAEATDSKAAARLGSDMGEFYMPYPGTRINQETVS
Rv1860|M.tuberculosis_H37Rv         DTRIVLGRLDQKLYASAEATDSKAAARLGSDMGEFYMPYPGTRINQETVS
MLBr_02055|M.leprae_Br4923          DTRIVLGRLDQKLYASAEADNIKAAVRLGSDMGEFYLPYPGTRINQETIP
MMAR_2737|M.marinum_M               DTRVVLGRLDQKLYASAEATNPKAAVRLGSDMGEFFMPYPGTRINQETIP
MUL_3017|M.ulcerans_Agy99           DTRVVLGRLDQKLYASAEATNPKAAVRLGSDMGEFFMPYPGTRINQETIP
MAV_2859|M.avium_104                DTRIVMGRLDQKLYASAEANNAKAAVRLGSDMGEFFMPYPGTRINQDSTP
MAB_2436|M.abscessus_ATCC_1997      NGSILLGRLDLKLFAGAEPDNQKAARRLASDMGEFFMPYPGNRVNQEDQS
                                    :  :::**** **:*.**  : *** **.******::*:**.*:**:   

MSMEG_3618|M.smegmatis_MC2_155      LN-ADGMPGVASYYEVKFTDANKPAGQIWAGVVGQPVAPGTPRGQRTPER
TH_1368|M.thermoresistible__bu      LN-AEGMQGSAAYYEVEFTDENRPNGQIWAGVVGSPTPPGTPRGQRAPER
Mflv_3345|M.gilvum_PYR-GCK          LD-ANGMTGVASYYEVKFTDTNKPNGQIWAGVVGAPVAPGTPRGQRTPER
Mvan_3075|M.vanbaalenii_PYR-1       LD-NN---GVASYYEVKFTDTNKPNGQIWAGVVGEPVAPGTPRGQRTPER
Mb1891|M.bovis_AF2122/97            LD-ANGVSGSASYYEVKFSDPSKPNGQIWTGVIGS--PAANAPDAGPPQR
Rv1860|M.tuberculosis_H37Rv         LD-ANGVSGSASYYEVKFSDPSKPNGQIWTGVIGS--PAANAPDAGPPQR
MLBr_02055|M.leprae_Br4923          LH-ANGIAGSASYYEVKFSDPNKPIGQICTSVVGS--PAASTPDVGPSQR
MMAR_2737|M.marinum_M               LN-ANGITGSASYYEVKFSDESKPNGQIWTGVVGT--PAGSTPNEGPPQR
MUL_3017|M.ulcerans_Agy99           LN-ANGITGSASYYEVKFSDESKPNGQIWTGVVGT--PAGSTPNEGPPQR
MAV_2859|M.avium_104                LNGANGSTGSASYYEVKFSDASKPNGQIWTGVIGS--ANG-----GNAQR
MAB_2436|M.abscessus_ATCC_1997      FD-VAGMSAASSYYEVKFDDAAKEPGQIWAAAVGK-----------GKDR
                                    :.      . ::****:* *  :  *** :..:*              :*

MSMEG_3618|M.smegmatis_MC2_155      WFVVWLGTANNPIDKDAAVALANSIRPWAPPPPPPPAP------------
TH_1368|M.thermoresistible__bu      WFVVWLGSENNPVDKAAAVALAESIRPWEPPPAPP---------------
Mflv_3345|M.gilvum_PYR-GCK          WFVVWLGTATNPVPQGEAVTLANSIRPWAPPPPPP-AD------------
Mvan_3075|M.vanbaalenii_PYR-1       WFVVWLGTATNPIPQAEAVTLANSIRPWTPPPPPPPAD------------
Mb1891|M.bovis_AF2122/97            WFVVWLGTANNPVDKGAAKALAESIRPLVAP-PPAPAP------------
Rv1860|M.tuberculosis_H37Rv         WFVVWLGTANNPVDKGAAKALAESIRPLVAP-PPAPAP------------
MLBr_02055|M.leprae_Br4923          WFVVWLGTSNNPVDKGAAKELAESIRSEMAP-IPASVS------------
MMAR_2737|M.marinum_M               WFVVWLGTSNDPVDKGAAKVLAESIRPWMPP--PAPAP------------
MUL_3017|M.ulcerans_Agy99           WFVVWLGTSNDPVDKGAAKVLAESIRPWMPPPAPAPAP------------
MAV_2859|M.avium_104                WFVVWLGTSNDPVDKVAAKALAESIQAWTPPPAPPAAPGGPGAPAPGAPG
MAB_2436|M.abscessus_ATCC_1997      WFIVWLGTAASPVDKGVAKALTESIRPWTPPTPPTPSAAPPADP------
                                    **:****:  .*: :  *  *::**:.  .*  *.               

MSMEG_3618|M.smegmatis_MC2_155      -------ADPADPNAAP--PPPDPNAPPARPGVGVP--------VPVT-D
TH_1368|M.thermoresistible__bu      -------ADPAGPQAQ-----PDPDAPPARPGVGVP--------VPVT-D
Mflv_3345|M.gilvum_PYR-GCK          -------PNAPVPPADPNAPPADPNAAPPRPAVGVP--------VPVDPN
Mvan_3075|M.vanbaalenii_PYR-1       -------PNAPVPPADPNAPPPDPNAPAPRPAVGVP--------VPVDPN
Mb1891|M.bovis_AF2122/97            --------APAEPAP---------APAPAGEVAPTP-----------TTP
Rv1860|M.tuberculosis_H37Rv         --------APAEPAP---------APAPAGEVAPTP-----------TTP
MLBr_02055|M.leprae_Br4923          --------AP----------------APVG--------------------
MMAR_2737|M.marinum_M               --------APGEPAPQPGAPEPVPAPAPAPAAGVAP-----------TVA
MUL_3017|M.ulcerans_Agy99           --------APGEPAPQPGAPEPVPAPAPAPAAGVAP-----------TVA
MAV_2859|M.avium_104                APAPGAPAAPGAPAPAAPAPAAPGAPAAPGAPAPAPGQAPAVEVSPTPTP
MAB_2436|M.abscessus_ATCC_1997      -------NQPAPPPADPNQPPPPPADPNQPPAPPAPTAPAAPAAEPAAPG
                                             .                .                       

MSMEG_3618|M.smegmatis_MC2_155      APPEMMPPA---------
TH_1368|M.thermoresistible__bu      APPEMMPPA---------
Mflv_3345|M.gilvum_PYR-GCK          TAPGMLPPA---------
Mvan_3075|M.vanbaalenii_PYR-1       TAPGMLPPA---------
Mb1891|M.bovis_AF2122/97            TPQRTLPA----------
Rv1860|M.tuberculosis_H37Rv         TPQRTLPA----------
MLBr_02055|M.leprae_Br4923          ------------------
MMAR_2737|M.marinum_M               PAPRTQPT----------
MUL_3017|M.ulcerans_Agy99           PAPRTQPT----------
MAV_2859|M.avium_104                TPQQTLSA----------
MAB_2436|M.abscessus_ATCC_1997      QPAPPTPPAAPPAPGVPV