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YESDSMSHRRSGLSKKLTLAAVTGMTAVAVALPSVAHADPEPPPPPPGNTFLPAPPPADPNAPAPAPAPA PAPAPAPAPALAPAPAPGAPAPAPAPAPAPADPNAPAPAPADPNAPAPAPAEEPPAPEPGRVDNAAGGFS YVVPEGWQVSDATQLSYGQALLTKTVAEGAEPPNDTSVLLGRLDLKLFAGAEPDNNKAAVRLASDMGEFF MPFPGTRVNQQTVQLNADGMPGVASYYEVKFTDANKPAGQIWAGVVGQPVAPGTPRGQRTPERWFVVWLG TANNPIDKDAAVALANSIRPWAPPPPPPPAPADPADPNAAPPPPDPNAPPARPGVGVPVPVTDAPPEMMP PA*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_3618 | - | - | 100% (353) | alanine and proline-rich secreted protein apa |
M. smegmatis MC2 155 | MSMEG_0679 | - | 3e-18 | 40.30% (134) | hypothetical protein MSMEG_0679 |
M. smegmatis MC2 155 | MSMEG_5700 | - | 3e-17 | 31.64% (373) | secreted protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1891 | apa | 2e-91 | 51.40% (358) | hypothetical protein Mb1891 |
M. gilvum PYR-GCK | Mflv_3345 | - | 1e-135 | 69.21% (367) | fibronectin-attachment family protein |
M. tuberculosis H37Rv | Rv1860 | apa | 7e-91 | 51.12% (358) | hypothetical protein Rv1860 |
M. leprae Br4923 | MLBr_02055 | modD | 2e-68 | 47.06% (323) | putative cell surface protein (associated with virulence) |
M. abscessus ATCC 19977 | MAB_2436 | - | 3e-78 | 48.57% (350) | hypothetical protein MAB_2436 |
M. marinum M | MMAR_2737 | apa | 1e-103 | 56.82% (352) | alanine and proline rich secreted protein Apa |
M. avium 104 | MAV_2859 | - | 3e-94 | 51.90% (368) | ModD protein |
M. thermoresistible (build 8) | TH_1368 | modD | 1e-108 | 76.17% (256) | ALANINE AND PROLINE RICH SECRETED PROTEIN APA (FIBRONECTIN |
M. ulcerans Agy99 | MUL_3017 | apa | 7e-89 | 51.56% (353) | alanine and proline rich secreted protein Apa |
M. vanbaalenii PYR-1 | Mvan_3075 | - | 1e-128 | 65.75% (365) | fibronectin-attachment family protein |
CLUSTAL 2.0.9 multiple sequence alignment MSMEG_3618|M.smegmatis_MC2_155 --MYESDSMSHRRSGLSKKLTLAAVTGMT----AVAVALPSVAHADPEPP TH_1368|M.thermoresistible__bu -------------------------------------------------- Mflv_3345|M.gilvum_PYR-GCK MTMDQPNVFPHRRAGTPTSIRRSVVTGATTAALAAALALPGIANAQPAPT Mvan_3075|M.vanbaalenii_PYR-1 --MDQPDMHAKRRKGLPTSFRRSALTGAT-AALTAVFTLPAVAYAQPAPP Mb1891|M.bovis_AF2122/97 --MHQVDPNLTRRKGRLAALAIAAMASAS----LVTVAVPATANADPEPA Rv1860|M.tuberculosis_H37Rv --MHQVDPNLTRRKGRLAALAIAAMASAS----LVTVAVPATANADPEPA MLBr_02055|M.leprae_Br4923 --MNQVDLDSTHRKGLWAILAIAVVASAS----AFTMPLPAAANADPAPL MMAR_2737|M.marinum_M --MHEVDPNKRRRHGLWTTLALAAVSSAS----VVSIALPATASADPAPA MUL_3017|M.ulcerans_Agy99 --MHEVDPNKRRRHGLWTTLALAAVSSAS----VVSIALPATASADPAPA MAV_2859|M.avium_104 --MDQVEATSTRRKGLWTTLAITTVSGAS----AVAIALPATSHADPEVP MAB_2436|M.abscessus_ATCC_1997 --MQQPRATSAAKRTHRARVIAATIAVTSLSG-AGAYTLAATP-VDQAPA MSMEG_3618|M.smegmatis_MC2_155 P----PPPGNTFLPAPPPADPNAPAPAPAPAPAPAPAPAPALAPAPAPGA TH_1368|M.thermoresistible__bu --------------VPPPGQP----------------------------- Mflv_3345|M.gilvum_PYR-GCK PTPAPPPPAVGAPQAPAPDAPAAPAPAPPADPN----------------A Mvan_3075|M.vanbaalenii_PYR-1 PSPAPPPAVEAPPVPPPPVDPNAPVPPPPVDPN----------------A Mb1891|M.bovis_AF2122/97 PPVPTTAASPPSTAAAPPAPATPVAPPPPAAANT---------PNAQPGD Rv1860|M.tuberculosis_H37Rv PPVPTTAASPPSTAAAPPAPATPVAPPPPAAANT---------PNAQPGD MLBr_02055|M.leprae_Br4923 P---------PSTATAAPSPAQEIITPLPGAPVS---------SEAQPGD MMAR_2737|M.marinum_M P--------APSTTAAP--PADPNAAPPPADPNA---------PPPPPAD MUL_3017|M.ulcerans_Agy99 P--------APSTTAAP--PADPNAAPPPADP------------------ MAV_2859|M.avium_104 TPVPPSTATAPPAAPAPNGQPAPNAQPAPAAPAPNGQPAP---AAPAPND MAB_2436|M.abscessus_ATCC_1997 TVRTANIHLVTTDAPPPPAPPATPAPGQPAPNPE---------TPTTVTT .. . MSMEG_3618|M.smegmatis_MC2_155 PAPAPAPAP-------APADPNAPAPAPADPNAPAPAPAEE--PPAPEPG TH_1368|M.thermoresistible__bu -------------------------PAPADPNAPA--------EPAPEP- Mflv_3345|M.gilvum_PYR-GCK PAPAAPPAT-------PPADPNAPVPPPADPNAPAPAGPEAPAAPAPEPG Mvan_3075|M.vanbaalenii_PYR-1 PVPPP-----------PPVDPNAPVPPPADPNAPVP--------PAPEPG Mb1891|M.bovis_AF2122/97 PNAAP-----------PPADPNAPPPPVIAPNAPQP-------------V Rv1860|M.tuberculosis_H37Rv PNAAP-----------PPADPNAPPPPVIAPNAPQP-------------V MLBr_02055|M.leprae_Br4923 PNA-------------PSLDPNAPYPLAVDPNAG---------------- MMAR_2737|M.marinum_M PNAPPPPPADPNAPPPPPADPNAPPPPVVDPNAPEP-------------G MUL_3017|M.ulcerans_Agy99 ---------------------NAPPPPVVDPNAPEP-------------G MAV_2859|M.avium_104 PNAAPPPAG-APPNGAPPAPPNGAPPPPVDPNAPPPPPADP------NAG MAB_2436|M.abscessus_ATCC_1997 PPPAP------------APGQPAPPTPPPAPGAPAD------------GG . *.* MSMEG_3618|M.smegmatis_MC2_155 RVDNAAGGFSYVVPEGWQVSDATQLSYGQALLTKTV--AEGAE----PPN TH_1368|M.thermoresistible__bu RENNAAGGFSYVVPGGWQVSDATQLSYGQALLTKIP--PPGSQQ---PPN Mflv_3345|M.gilvum_PYR-GCK RVDNAAGGFSYVVPAGWKVSDATQLSYGQALLSKLP--PEGSPPDAQPPN Mvan_3075|M.vanbaalenii_PYR-1 RIDNAAGGFSYVVPAGWEVSDSTQLSYGQALLTKLP--PEGAPPDAQPPN Mb1891|M.bovis_AF2122/97 RIDNPVGGFSFALPAGWVESDAAHLDYGSALLSKTTGDPPFPGQPPPVAN Rv1860|M.tuberculosis_H37Rv RIDNPVGGFSFALPAGWVESDAAHFDYGSALLSKTTGDPPFPGQPPPVAN MLBr_02055|M.leprae_Br4923 RITNAVGGFSFVLPAGWVESEASHLDYGSVLLSKAIEQPPVLGQPTVVAT MMAR_2737|M.marinum_M RVNNAVGGFSFVVPAGWVESDASHLDYGSALLSKMTGEPPMPGQAPPIAN MUL_3017|M.ulcerans_Agy99 RVNNAVGGFSSVVPAGWVESDASHLDYGSALLSKMTGEPPMPGQAPPIAN MAV_2859|M.avium_104 RIPNAVGGFSYVLPAGWVESDASHLDYGSALLSKVTGPPPMPDQPPPVAN MAB_2436|M.abscessus_ATCC_1997 RVNNDQGGFSFVVPQGWVQSDARRLTYGSALLTNPA------------AP * * **** .:* ** *:: :: **..**:: . MSMEG_3618|M.smegmatis_MC2_155 DTSVLLGRLDLKLFAGAEPDNNKAAVRLASDMGEFFMPFPGTRVNQQTVQ TH_1368|M.thermoresistible__bu DTSILLGRLDLKLFAGAEPDNTKAANRLASDMGEFFMPYPGTRINQETVP Mflv_3345|M.gilvum_PYR-GCK DTSVLLGRLDLKLFAGAETDNTKAAQRLASDMGEFFMPFPGTRVNQQVVP Mvan_3075|M.vanbaalenii_PYR-1 DTSVLLGRLDLKLFAGAENDNTKAAQRLASDMGEFFMPFPGTRVNQQVVP Mb1891|M.bovis_AF2122/97 DTRIVLGRLDQKLYASAEATDSKAAARLGSDMGEFYMPYPGTRINQETVS Rv1860|M.tuberculosis_H37Rv DTRIVLGRLDQKLYASAEATDSKAAARLGSDMGEFYMPYPGTRINQETVS MLBr_02055|M.leprae_Br4923 DTRIVLGRLDQKLYASAEADNIKAAVRLGSDMGEFYLPYPGTRINQETIP MMAR_2737|M.marinum_M DTRVVLGRLDQKLYASAEATNPKAAVRLGSDMGEFFMPYPGTRINQETIP MUL_3017|M.ulcerans_Agy99 DTRVVLGRLDQKLYASAEATNPKAAVRLGSDMGEFFMPYPGTRINQETIP MAV_2859|M.avium_104 DTRIVMGRLDQKLYASAEANNAKAAVRLGSDMGEFFMPYPGTRINQDSTP MAB_2436|M.abscessus_ATCC_1997 NGSILLGRLDLKLFAGAEPDNQKAARRLASDMGEFFMPYPGNRVNQEDQS : :::**** **:*.** : *** **.******::*:**.*:**: MSMEG_3618|M.smegmatis_MC2_155 LN-ADGMPGVASYYEVKFTDANKPAGQIWAGVVGQPVAPGTPRGQRTPER TH_1368|M.thermoresistible__bu LN-AEGMQGSAAYYEVEFTDENRPNGQIWAGVVGSPTPPGTPRGQRAPER Mflv_3345|M.gilvum_PYR-GCK LD-ANGMTGVASYYEVKFTDTNKPNGQIWAGVVGAPVAPGTPRGQRTPER Mvan_3075|M.vanbaalenii_PYR-1 LD-NN---GVASYYEVKFTDTNKPNGQIWAGVVGEPVAPGTPRGQRTPER Mb1891|M.bovis_AF2122/97 LD-ANGVSGSASYYEVKFSDPSKPNGQIWTGVIGS--PAANAPDAGPPQR Rv1860|M.tuberculosis_H37Rv LD-ANGVSGSASYYEVKFSDPSKPNGQIWTGVIGS--PAANAPDAGPPQR MLBr_02055|M.leprae_Br4923 LH-ANGIAGSASYYEVKFSDPNKPIGQICTSVVGS--PAASTPDVGPSQR MMAR_2737|M.marinum_M LN-ANGITGSASYYEVKFSDESKPNGQIWTGVVGT--PAGSTPNEGPPQR MUL_3017|M.ulcerans_Agy99 LN-ANGITGSASYYEVKFSDESKPNGQIWTGVVGT--PAGSTPNEGPPQR MAV_2859|M.avium_104 LNGANGSTGSASYYEVKFSDASKPNGQIWTGVIGS--ANG-----GNAQR MAB_2436|M.abscessus_ATCC_1997 FD-VAGMSAASSYYEVKFDDAAKEPGQIWAAAVGK-----------GKDR :. . ::****:* * : *** :..:* :* MSMEG_3618|M.smegmatis_MC2_155 WFVVWLGTANNPIDKDAAVALANSIRPWAPPPPPPPAP------------ TH_1368|M.thermoresistible__bu WFVVWLGSENNPVDKAAAVALAESIRPWEPPPAPP--------------- Mflv_3345|M.gilvum_PYR-GCK WFVVWLGTATNPVPQGEAVTLANSIRPWAPPPPPP-AD------------ Mvan_3075|M.vanbaalenii_PYR-1 WFVVWLGTATNPIPQAEAVTLANSIRPWTPPPPPPPAD------------ Mb1891|M.bovis_AF2122/97 WFVVWLGTANNPVDKGAAKALAESIRPLVAP-PPAPAP------------ Rv1860|M.tuberculosis_H37Rv WFVVWLGTANNPVDKGAAKALAESIRPLVAP-PPAPAP------------ MLBr_02055|M.leprae_Br4923 WFVVWLGTSNNPVDKGAAKELAESIRSEMAP-IPASVS------------ MMAR_2737|M.marinum_M WFVVWLGTSNDPVDKGAAKVLAESIRPWMPP--PAPAP------------ MUL_3017|M.ulcerans_Agy99 WFVVWLGTSNDPVDKGAAKVLAESIRPWMPPPAPAPAP------------ MAV_2859|M.avium_104 WFVVWLGTSNDPVDKVAAKALAESIQAWTPPPAPPAAPGGPGAPAPGAPG MAB_2436|M.abscessus_ATCC_1997 WFIVWLGTAASPVDKGVAKALTESIRPWTPPTPPTPSAAPPADP------ **:****: .*: : * *::**:. .* *. MSMEG_3618|M.smegmatis_MC2_155 -------ADPADPNAAP--PPPDPNAPPARPGVGVP--------VPVT-D TH_1368|M.thermoresistible__bu -------ADPAGPQAQ-----PDPDAPPARPGVGVP--------VPVT-D Mflv_3345|M.gilvum_PYR-GCK -------PNAPVPPADPNAPPADPNAAPPRPAVGVP--------VPVDPN Mvan_3075|M.vanbaalenii_PYR-1 -------PNAPVPPADPNAPPPDPNAPAPRPAVGVP--------VPVDPN Mb1891|M.bovis_AF2122/97 --------APAEPAP---------APAPAGEVAPTP-----------TTP Rv1860|M.tuberculosis_H37Rv --------APAEPAP---------APAPAGEVAPTP-----------TTP MLBr_02055|M.leprae_Br4923 --------AP----------------APVG-------------------- MMAR_2737|M.marinum_M --------APGEPAPQPGAPEPVPAPAPAPAAGVAP-----------TVA MUL_3017|M.ulcerans_Agy99 --------APGEPAPQPGAPEPVPAPAPAPAAGVAP-----------TVA MAV_2859|M.avium_104 APAPGAPAAPGAPAPAAPAPAAPGAPAAPGAPAPAPGQAPAVEVSPTPTP MAB_2436|M.abscessus_ATCC_1997 -------NQPAPPPADPNQPPPPPADPNQPPAPPAPTAPAAPAAEPAAPG . . MSMEG_3618|M.smegmatis_MC2_155 APPEMMPPA--------- TH_1368|M.thermoresistible__bu APPEMMPPA--------- Mflv_3345|M.gilvum_PYR-GCK TAPGMLPPA--------- Mvan_3075|M.vanbaalenii_PYR-1 TAPGMLPPA--------- Mb1891|M.bovis_AF2122/97 TPQRTLPA---------- Rv1860|M.tuberculosis_H37Rv TPQRTLPA---------- MLBr_02055|M.leprae_Br4923 ------------------ MMAR_2737|M.marinum_M PAPRTQPT---------- MUL_3017|M.ulcerans_Agy99 PAPRTQPT---------- MAV_2859|M.avium_104 TPQQTLSA---------- MAB_2436|M.abscessus_ATCC_1997 QPAPPTPPAAPPAPGVPV