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M. thermoresistible (build 8) TH_1368 (modD)

annotation: ALANINE AND PROLINE RICH SECRETED PROTEIN APA (FIBRONECTIN ATTACHMENT PROTEIN) (Immunogenic protein MPT32) (Antigen MPT-32) (45-kDa glycoprotein) (45/47 kDa antigen)
coordinates: 2599411 - 2600133
length: 241

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1368modD-100% (241)ALANINE AND PROLINE RICH SECRETED PROTEIN APA (FIBRONECTIN ATTACHMENT PROTEIN) (Immunogenic protein MPT32) (Antigen MPT-32) (45-kDa glycoprotein) (45/47 kDa antigen)
M. thermoresistible (build 8)TH_1481ftsY2e-0536.47% (85) PROBABLE CELL DIVISION PROTEIN FTSY (SRP RECEPTOR) (SIGNAL

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1891apa2e-7056.80% (250) hypothetical protein Mb1891
M. gilvum PYR-GCKMflv_3345-1e-10372.05% (254) fibronectin-attachment family protein
M. tuberculosis H37RvRv1860apa6e-7056.40% (250) hypothetical protein Rv1860
M. leprae Br4923MLBr_02055modD7e-5957.75% (213) putative cell surface protein (associated with virulence)
M. abscessus ATCC 19977MAB_2436-1e-6452.85% (246) hypothetical protein MAB_2436
M. marinum MMMAR_2737apa3e-7960.96% (251) alanine and proline rich secreted protein Apa
M. avium 104MAV_2859-1e-7559.29% (253) ModD protein
M. smegmatis MC2 155MSMEG_3618-1e-10876.17% (256) alanine and proline-rich secreted protein apa
M. ulcerans Agy99MUL_3017apa3e-7860.00% (250) alanine and proline rich secreted protein Apa
M. vanbaalenii PYR-1Mvan_3075-7e-9869.14% (256) fibronectin-attachment family protein

CLUSTAL 2.0.9 multiple sequence alignment


TH_1368|M.thermoresistible__bu      --------------------------------------------------
MSMEG_3618|M.smegmatis_MC2_155      --MYESDSMSHRRSGLSKKLTLAAVTGMT----AVAVALPSVAHADPEPP
Mflv_3345|M.gilvum_PYR-GCK          MTMDQPNVFPHRRAGTPTSIRRSVVTGATTAALAAALALPGIANAQPAPT
Mvan_3075|M.vanbaalenii_PYR-1       --MDQPDMHAKRRKGLPTSFRRSALTGAT-AALTAVFTLPAVAYAQPAPP
Mb1891|M.bovis_AF2122/97            --MHQVDPNLTRRKGRLAALAIAAMASAS----LVTVAVPATANADPEPA
Rv1860|M.tuberculosis_H37Rv         --MHQVDPNLTRRKGRLAALAIAAMASAS----LVTVAVPATANADPEPA
MLBr_02055|M.leprae_Br4923          --MNQVDLDSTHRKGLWAILAIAVVASAS----AFTMPLPAAANADPAPL
MMAR_2737|M.marinum_M               --MHEVDPNKRRRHGLWTTLALAAVSSAS----VVSIALPATASADPAPA
MUL_3017|M.ulcerans_Agy99           --MHEVDPNKRRRHGLWTTLALAAVSSAS----VVSIALPATASADPAPA
MAV_2859|M.avium_104                --MDQVEATSTRRKGLWTTLAITTVSGAS----AVAIALPATSHADPEVP
MAB_2436|M.abscessus_ATCC_1997      --MQQPRATSAAKRTHRARVIAATIAVTSLSG-AGAYTLAATP-VDQAPA
                                                                                      

TH_1368|M.thermoresistible__bu      --------------VPPPGQP-----------------------------
MSMEG_3618|M.smegmatis_MC2_155      P----PPPGNTFLPAPPPADPNAPAPAPAPAPAPAPAPAPALAPAPAPGA
Mflv_3345|M.gilvum_PYR-GCK          PTPAPPPPAVGAPQAPAPDAPAAPAPAPPADPNAPAPAAPPATPPADPN-
Mvan_3075|M.vanbaalenii_PYR-1       PSPAPPPAVEAPPVPPPPVDPNAPVPPPPVDPNAPVPPP----PPVDPN-
Mb1891|M.bovis_AF2122/97            PPVPTTAASPPSTAAAPPAPATPVAPPPPAAANT------PNAQPGDPNA
Rv1860|M.tuberculosis_H37Rv         PPVPTTAASPPSTAAAPPAPATPVAPPPPAAANT------PNAQPGDPNA
MLBr_02055|M.leprae_Br4923          P---------PSTATAAPSPAQEIITPLPGAPVS------SEAQPGDPNA
MMAR_2737|M.marinum_M               P--------APSTTAAP--PADPNAAPPPADPNA------PPPPPADPNA
MUL_3017|M.ulcerans_Agy99           P--------APSTTAAP--PADPNAAPPPADP------------------
MAV_2859|M.avium_104                TPVPPSTATAPPAAPAPNGQPAPNAQPAPAAPAPNGQPAPAAPAPNDPNA
MAB_2436|M.abscessus_ATCC_1997      TVRTANIHLVTTDAPPPPAPPATPAPGQPAPNPE---------TPTTVTT
                                                   ..   .                             

TH_1368|M.thermoresistible__bu      ------------PAPADPNAPA----------------EPAPEP------
MSMEG_3618|M.smegmatis_MC2_155      PAP----APAPAPAPADPNAPAPAPADPNAPAPAPAEEPPAPEPG-----
Mflv_3345|M.gilvum_PYR-GCK          ---------APVPPPADPNAPAPAGPE--------APAAPAPEPG-----
Mvan_3075|M.vanbaalenii_PYR-1       ---------APVPPPADPNAPVP----------------PAPEPG-----
Mb1891|M.bovis_AF2122/97            AP-----------PPADPNAPPPP-----------VIAPNAPQP------
Rv1860|M.tuberculosis_H37Rv         AP-----------PPADPNAPPPP-----------VIAPNAPQP------
MLBr_02055|M.leprae_Br4923          -------------PSLDPNAPYPL-----------AVDPNAG--------
MMAR_2737|M.marinum_M               PPPPPADPNAPPPPPADPNAPPPP-----------VVDPNAPEP------
MUL_3017|M.ulcerans_Agy99           ------------------NAPPPP-----------VVDPNAPEP------
MAV_2859|M.avium_104                APPPAG-APPNGAPPAPPNGAPPP-----------PVDPNAPPPPPADPN
MAB_2436|M.abscessus_ATCC_1997      PP--------PAPAPGQPAPPTPP------------PAPGAPADG-----
                                                        .                   *         

TH_1368|M.thermoresistible__bu      --RENNAAGGFSYVVPGGWQVSDATQLSYGQALLTKIP--PPGSQQ---P
MSMEG_3618|M.smegmatis_MC2_155      --RVDNAAGGFSYVVPEGWQVSDATQLSYGQALLTKTV--AEGAE----P
Mflv_3345|M.gilvum_PYR-GCK          --RVDNAAGGFSYVVPAGWKVSDATQLSYGQALLSKLP--PEGSPPDAQP
Mvan_3075|M.vanbaalenii_PYR-1       --RIDNAAGGFSYVVPAGWEVSDSTQLSYGQALLTKLP--PEGAPPDAQP
Mb1891|M.bovis_AF2122/97            -VRIDNPVGGFSFALPAGWVESDAAHLDYGSALLSKTTGDPPFPGQPPPV
Rv1860|M.tuberculosis_H37Rv         -VRIDNPVGGFSFALPAGWVESDAAHFDYGSALLSKTTGDPPFPGQPPPV
MLBr_02055|M.leprae_Br4923          --RITNAVGGFSFVLPAGWVESEASHLDYGSVLLSKAIEQPPVLGQPTVV
MMAR_2737|M.marinum_M               -GRVNNAVGGFSFVVPAGWVESDASHLDYGSALLSKMTGEPPMPGQAPPI
MUL_3017|M.ulcerans_Agy99           -GRVNNAVGGFSSVVPAGWVESDASHLDYGSALLSKMTGEPPMPGQAPPI
MAV_2859|M.avium_104                AGRIPNAVGGFSYVLPAGWVESDASHLDYGSALLSKVTGPPPMPDQPPPV
MAB_2436|M.abscessus_ATCC_1997      -GRVNNDQGGFSFVVPQGWVQSDARRLTYGSALLTNPA------------
                                      *  *  **** .:* **  *:: :: **..**::              

TH_1368|M.thermoresistible__bu      PNDTSILLGRLDLKLFAGAEPDNTKAANRLASDMGEFFMPYPGTRINQET
MSMEG_3618|M.smegmatis_MC2_155      PNDTSVLLGRLDLKLFAGAEPDNNKAAVRLASDMGEFFMPFPGTRVNQQT
Mflv_3345|M.gilvum_PYR-GCK          PNDTSVLLGRLDLKLFAGAETDNTKAAQRLASDMGEFFMPFPGTRVNQQV
Mvan_3075|M.vanbaalenii_PYR-1       PNDTSVLLGRLDLKLFAGAENDNTKAAQRLASDMGEFFMPFPGTRVNQQV
Mb1891|M.bovis_AF2122/97            ANDTRIVLGRLDQKLYASAEATDSKAAARLGSDMGEFYMPYPGTRINQET
Rv1860|M.tuberculosis_H37Rv         ANDTRIVLGRLDQKLYASAEATDSKAAARLGSDMGEFYMPYPGTRINQET
MLBr_02055|M.leprae_Br4923          ATDTRIVLGRLDQKLYASAEADNIKAAVRLGSDMGEFYLPYPGTRINQET
MMAR_2737|M.marinum_M               ANDTRVVLGRLDQKLYASAEATNPKAAVRLGSDMGEFFMPYPGTRINQET
MUL_3017|M.ulcerans_Agy99           ANDTRVVLGRLDQKLYASAEATNPKAAVRLGSDMGEFFMPYPGTRINQET
MAV_2859|M.avium_104                ANDTRIVMGRLDQKLYASAEANNAKAAVRLGSDMGEFFMPYPGTRINQDS
MAB_2436|M.abscessus_ATCC_1997      APNGSILLGRLDLKLFAGAEPDNQKAARRLASDMGEFFMPYPGNRVNQED
                                    . :  :::**** **:*.**  : *** **.******::*:**.*:**: 

TH_1368|M.thermoresistible__bu      VPLN-AEGMQGSAAYYEVEFTDENRPNGQIWAGVVGSPTPPGTPRGQRAP
MSMEG_3618|M.smegmatis_MC2_155      VQLN-ADGMPGVASYYEVKFTDANKPAGQIWAGVVGQPVAPGTPRGQRTP
Mflv_3345|M.gilvum_PYR-GCK          VPLD-ANGMTGVASYYEVKFTDTNKPNGQIWAGVVGAPVAPGTPRGQRTP
Mvan_3075|M.vanbaalenii_PYR-1       VPLD-NN---GVASYYEVKFTDTNKPNGQIWAGVVGEPVAPGTPRGQRTP
Mb1891|M.bovis_AF2122/97            VSLD-ANGVSGSASYYEVKFSDPSKPNGQIWTGVIGS--PAANAPDAGPP
Rv1860|M.tuberculosis_H37Rv         VSLD-ANGVSGSASYYEVKFSDPSKPNGQIWTGVIGS--PAANAPDAGPP
MLBr_02055|M.leprae_Br4923          IPLH-ANGIAGSASYYEVKFSDPNKPIGQICTSVVGS--PAASTPDVGPS
MMAR_2737|M.marinum_M               IPLN-ANGITGSASYYEVKFSDESKPNGQIWTGVVGT--PAGSTPNEGPP
MUL_3017|M.ulcerans_Agy99           IPLN-ANGITGSASYYEVKFSDESKPNGQIWTGVVGT--PAGSTPNEGPP
MAV_2859|M.avium_104                TPLNGANGSTGSASYYEVKFSDASKPNGQIWTGVIGS--ANG-----GNA
MAB_2436|M.abscessus_ATCC_1997      QSFD-VAGMSAASSYYEVKFDDAAKEPGQIWAAAVGK-----------GK
                                      :.      . ::****:* *  :  *** :..:*              

TH_1368|M.thermoresistible__bu      ERWFVVWLGSENNPVDKAAAVALAESIRPWEPPPAPP-------------
MSMEG_3618|M.smegmatis_MC2_155      ERWFVVWLGTANNPIDKDAAVALANSIRPWAPPPPPPPAP----------
Mflv_3345|M.gilvum_PYR-GCK          ERWFVVWLGTATNPVPQGEAVTLANSIRPWAPPPPPP-ADPN--------
Mvan_3075|M.vanbaalenii_PYR-1       ERWFVVWLGTATNPIPQAEAVTLANSIRPWTPPPPPPPADPN--------
Mb1891|M.bovis_AF2122/97            QRWFVVWLGTANNPVDKGAAKALAESIRPLVAP-PPAPAP----------
Rv1860|M.tuberculosis_H37Rv         QRWFVVWLGTANNPVDKGAAKALAESIRPLVAP-PPAPAP----------
MLBr_02055|M.leprae_Br4923          QRWFVVWLGTSNNPVDKGAAKELAESIRSEMAP-IPASVS----------
MMAR_2737|M.marinum_M               QRWFVVWLGTSNDPVDKGAAKVLAESIRPWMPP--PAPAP----------
MUL_3017|M.ulcerans_Agy99           QRWFVVWLGTSNDPVDKGAAKVLAESIRPWMPPPAPAPAP----------
MAV_2859|M.avium_104                QRWFVVWLGTSNDPVDKVAAKALAESIQAWTPPPAPPAAPGGPGAPAPGA
MAB_2436|M.abscessus_ATCC_1997      DRWFIVWLGTAASPVDKGVAKALTESIRPWTPPTPPTPSAAPPADPNQ--
                                    :***:****:  .*: :  *  *::**:.  .*  *.             

TH_1368|M.thermoresistible__bu      ---------ADPAGPQAQP----DPDAPPARPGVGVPVPVT---------
MSMEG_3618|M.smegmatis_MC2_155      ---------ADPADPNAAPPP-PDPNAPPARPGVGVPVPVT---------
Mflv_3345|M.gilvum_PYR-GCK          -------APVPPADPNAPP---ADPNAAPPRPAVGVPVPVDP--------
Mvan_3075|M.vanbaalenii_PYR-1       -------APVPPADPNAPP---PDPNAPAPRPAVGVPVPVDP--------
Mb1891|M.bovis_AF2122/97            ----------APAEPAP----------APAPAGEVAPTP-----------
Rv1860|M.tuberculosis_H37Rv         ----------APAEPAP----------APAPAGEVAPTP-----------
MLBr_02055|M.leprae_Br4923          ----------AP-----------------APVG-----------------
MMAR_2737|M.marinum_M               ----------APGEPAPQPGA-PEPVPAPAPAPAAGVAP-----------
MUL_3017|M.ulcerans_Agy99           ----------APGEPAPQPGA-PEPVPAPAPAPAAGVAP-----------
MAV_2859|M.avium_104                PGAPAPGAPAAPGAPAPAAPA-PAAPGAPAAPGAPAPAPGQAPAVEVSPT
MAB_2436|M.abscessus_ATCC_1997      -------PAPPPADPNQPPPPPADPNQPPAPPAPTAPAAPAAEPAAPGQP
                                               *                 .                    

TH_1368|M.thermoresistible__bu      -DAPPEMMPPA-----
MSMEG_3618|M.smegmatis_MC2_155      -DAPPEMMPPA-----
Mflv_3345|M.gilvum_PYR-GCK          -NTAPGMLPPA-----
Mvan_3075|M.vanbaalenii_PYR-1       -NTAPGMLPPA-----
Mb1891|M.bovis_AF2122/97            TTPTPQRTLPA-----
Rv1860|M.tuberculosis_H37Rv         TTPTPQRTLPA-----
MLBr_02055|M.leprae_Br4923          ----------------
MMAR_2737|M.marinum_M               TVAPAPRTQPT-----
MUL_3017|M.ulcerans_Agy99           TVAPAPRTQPT-----
MAV_2859|M.avium_104                PTPTPQQTLSA-----
MAB_2436|M.abscessus_ATCC_1997      APPTPPAAPPAPGVPV