For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. leprae Br4923 MLBr_00615 (subI)

annotation: putative sulphate-binding protein
coordinates: 748391 - 749437
length: 348

MFKDIGRFMRWRHSMVVGVTLASTTDVVAACHGGASDVVGGGTAHAHTSIALVAYSAPGPGWGKVIPAFN
DARSGDGVQVVTSYGASGDQSRGVVDGKPADIVNFSVETDITRLVKVGKVSKDWDTDATKGIPFGSVVTL
VVRTGNPKNIKDWDDLVRPGVEVIMPNPLSSGSAKWNLLAPYAAKSEGCRNSQAGIDFVNRLVAEHVKLR
LGSAREATDAFVQGSGDVLISYENEAIAAERQGKPVEHINPPVTFKIENPLAVVSTSAHLEVATAFKNFQ
YTTAAQGLWAQAGFRPVDPAVSADFSDQFPAPVKLWTIADLGGWSTVDPQLFDKNTGSITKVYMQATG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_00615subI-100% (348)putative sulphate-binding protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2422csubI1e-15376.47% (340) sulfate-binding lipoprotein
M. gilvum PYR-GCKMflv_2678-1e-12563.93% (341) sulfate ABC transporter, periplasmic sulfate-binding protein
M. tuberculosis H37RvRv2400csubI1e-15376.47% (340) sulfate-binding lipoprotein
M. abscessus ATCC 19977MAB_1652-1e-13367.96% (334) sulfate ABC transporter, sulfate-binding protein SubI
M. marinum MMMAR_3718subI1e-14976.18% (340) sulfate-binding lipoprotein SubI
M. avium 104MAV_1782-1e-15376.30% (346) sulfate ABC transporter, sulfate-binding protein
M. smegmatis MC2 155MSMEG_4533-1e-13667.54% (345) sulfate-binding protein
M. thermoresistible (build 8)TH_1447subI1e-13368.22% (343) PROBABLE SULFATE-BINDING LIPOPROTEIN SUBI
M. ulcerans Agy99MUL_3661subI1e-14675.00% (340) sulfate-binding lipoprotein SubI
M. vanbaalenii PYR-1Mvan_3875-1e-12364.22% (341) sulfate ABC transporter, periplasmic sulfate-binding protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb2422c|M.bovis_AF2122/97           MLSLTLSEASCIASASRWRHIIPAGVVCALIAGIGVGCHGGPSDVVGRAG
Rv2400c|M.tuberculosis_H37Rv        MLSLTLSEASCIASASRWRHIIPAGVVCALIAGIGVGCHGGPSDVVGRAG
MMAR_3718|M.marinum_M               -------MPQTFMGAARSRRPGTFGVIFALIAVLASACQGGPSDIAGGGG
MUL_3661|M.ulcerans_Agy99           -------MPQTFMGAARSRRPGTFGVIFALIAVLASACQGGPSDIAGGGG
MLBr_00615|M.leprae_Br4923          -------MFKDIGRFMRWRHSMVVGVTLASTTDVVAACHGGASDVVGG-G
MAV_1782|M.avium_104                ---------MDIRTAARWRP----VLALVLTAGVVAGCHGGASDAVGGTG
MAB_1652|M.abscessus_ATCC_1997      ----MIPSRSSARGSHRSSPKGLIAGALVVAAALTAACQGGPSDVPGGGR
Mflv_2678|M.gilvum_PYR-GCK          -------MLNPVRNLLKSPPRWRTAAALAVTTTLLAACGGGASDVAGDSG
Mvan_3875|M.vanbaalenii_PYR-1       -----------MRKILKSTRRWRTAAALTLSAAVLAACGGGASDVVGEEG
MSMEG_4533|M.smegmatis_MC2_155      ---------MPTTEKLTKFKFWRTATALAATGILAVGCGGGASDVAGDDG
TH_1447|M.thermoresistible__bu      ----MSGQKSPRPARSLRRRGARTLSVLAAGALLLAGCGGGASDVPG--G
                                                                .    :  .* **.**  *   

Mb2422c|M.bovis_AF2122/97           PDRA--HTSITLVAYAVPEPGWSAVIPAFNASEQGRGVQVITSYGASADQ
Rv2400c|M.tuberculosis_H37Rv        PDRA--HTSITLVAYAVPEPGWSAVIPAFNASEQGRGVQVITSYGASADQ
MMAR_3718|M.marinum_M               PTDA--HTSITLVAYSAPEPGWSTVIPAFNASEEGKDVQVITSYGASADQ
MUL_3661|M.ulcerans_Agy99           PTDA--HTSITLVAYSAPEPGWSTVIPAFNASEEGKDVQVITSYGASADQ
MLBr_00615|M.leprae_Br4923          TAHA--HTSIALVAYSAPGPGWGKVIPAFNDARSGDGVQVVTSYGASGDQ
MAV_1782|M.avium_104                PADA--HTSITLVAYSVPEPGWSKIIPAFNASDEGKGIQVVTSYGASGDQ
MAB_1652|M.abscessus_ATCC_1997      GGDA--DTTLTLVAYAVPEPGFREIIPAFNATEAGKGIQITQSYGASGDQ
Mflv_2678|M.gilvum_PYR-GCK          GSGS-AETTLTLVAFAVPEPGWSKAAPAFSATEEGEGVEVTASYGASGDQ
Mvan_3875|M.vanbaalenii_PYR-1       GNSD-AETTLTLVAFAVPEPGWSKVSPAFAATEEGKGVAVTGSYGASGDQ
MSMEG_4533|M.smegmatis_MC2_155      GADANAETTLTLVAYAVPEPGWSKIIPAFTATDEGKGVAVRTSFGASGDQ
TH_1447|M.thermoresistible__bu      GGDADADTTLTLVAYAVPEPGWSKVIPAFAATEEGTGVQVRASYGASGDQ
                                          .*:::***::.* **:    ***  :  * .: :  *:***.**

Mb2422c|M.bovis_AF2122/97           SRGVADGKPADLVNFSVEPDIARLVKAGKVDKDWDADATKGIPFGSVVTF
Rv2400c|M.tuberculosis_H37Rv        SRGVADGKPADLVNFSVEPDIARLVKAGKVDKDWDADATKGIPFGSVVTF
MMAR_3718|M.marinum_M               SRGVADGKPADLVNFSVEPDIARLVRAGKVAKDWDADATRGIPFESVVTL
MUL_3661|M.ulcerans_Agy99           SRGVADGKPADLVNFSVEPDIARLVRAGKVAKDWDAAATRGIPFESVVTL
MLBr_00615|M.leprae_Br4923          SRGVVDGKPADIVNFSVETDITRLVKVGKVSKDWDTDATKGIPFGSVVTL
MAV_1782|M.avium_104                SRGVVDGKPADVVNFSVEPDIARLVKAGKVAKDWNTDATKGIPFGSVVTL
MAB_1652|M.abscessus_ATCC_1997      SRGVEGGKPADIVNFSVEPDITRLVKAKKVSADWDKDAFGGIPFGSVVTL
Mflv_2678|M.gilvum_PYR-GCK          SRSVESGKPADVVNFSVEPDITRLVKAGKVDENWNAGPNKGIAFGSIVTF
Mvan_3875|M.vanbaalenii_PYR-1       SRAVESGKPADIVNFSVEPDITRLVKAGKVDENWNAGPNKGIAFGSVVSF
MSMEG_4533|M.smegmatis_MC2_155      SRAVVDGKPADIVNFSVEPDVTRLVKAGKVAEDWNAGATKGIPFGSVVSL
TH_1447|M.thermoresistible__bu      SRGVESGKPADLVNFSVEPDITRLVEAGKVAEGWNANATKGIPFGSVVTF
                                    **.* .*****:******.*::***.. **  .*:  .  **.* *:*::

Mb2422c|M.bovis_AF2122/97           VVRAGNPKNIRDWDDLLRPGIEVITPSPLSSGSAKWNLLAPYAAKSDGGR
Rv2400c|M.tuberculosis_H37Rv        VVRAGNPKNIRDWDDLLRPGIEVITPSPLSSGSAKWNLLAPYAAKSDGGR
MMAR_3718|M.marinum_M               VVREGNPKNIRDWDDLLRPGVEVITPSPLSSGSAKWNLLAPYAVKSEGGR
MUL_3661|M.ulcerans_Agy99           VVREGNPKNIRNWDDLLRPGVEVITPSPLSSGSAKWNLLAPYAVKSEGGR
MLBr_00615|M.leprae_Br4923          VVRTGNPKNIKDWDDLVRPGVEVIMPNPLSSGSAKWNLLAPYAAKSEGCR
MAV_1782|M.avium_104                VVRKGNPKHIKDWDDLLRPGVEVITPSPLSSGSAKWNLLAPYAVKSEGGA
MAB_1652|M.abscessus_ATCC_1997      VVRKGNPKHVKDWDDLLQPGLEVISPSPLSSGSAKWNLLAPYAAKSEGGK
Mflv_2678|M.gilvum_PYR-GCK          AVRPGNPKNIRTWDDLLQPGIEVITPSPLSSGAAKWNLLAPYAYASNGGQ
Mvan_3875|M.vanbaalenii_PYR-1       AVRPGNPKNIRTWDDLLQPGIEVITPSPLSSGAAKWNLLAPYAYASNGGK
MSMEG_4533|M.smegmatis_MC2_155      VVRQGNPKGIKDWDDLLQPGLEVVTPSPLSSGSAKWNLLAPYAAKSNGGQ
TH_1447|M.thermoresistible__bu      MVREGNPKNIRDWDDLLRPDVEVITPSPLSSGSAKWNLLAPYAVKSAGGQ
                                     ** **** :: ****::*.:**: *.*****:**********  * *  

Mb2422c|M.bovis_AF2122/97           NNQAGIDFVNTLVNEHVKLRPGSGREATDVFVQGSGDVLISYENEAIATE
Rv2400c|M.tuberculosis_H37Rv        NNQAGIDFVNTLVNEHVKLRPGSGREATDVFVQGSGDVLISYENEAIATE
MMAR_3718|M.marinum_M               NSQAGIDFVSRLVREHVKLRPGSGREATDVFVQGSGDVLISYENEAIATE
MUL_3661|M.ulcerans_Agy99           NSQAGIDFVSRLVREHVKLRPGSGREAIDVFVQGSGDVLISYENEAIATE
MLBr_00615|M.leprae_Br4923          NSQAGIDFVNRLVAEHVKLRLGSAREATDAFVQGSGDVLISYENEAIAAE
MAV_1782|M.avium_104                HGDAGVDFIRKLVTEHVKLRPGSGREATDVFVQGSGDVLISYENEAIATE
MAB_1652|M.abscessus_ATCC_1997      NPQAGLDFVSKLVREHVKMRPGSGREATEVFVQGSGDVLISYENEAIFTE
Mflv_2678|M.gilvum_PYR-GCK          NPEAGIEFVNKLVTEHVKLRPGSGREATDVFRQGSGDVLLAYENEALNFD
Mvan_3875|M.vanbaalenii_PYR-1       DPQAGIDFVNKLVTEHVKLRPGSGREATDVFRQGSGDVLLAYENEALNFD
MSMEG_4533|M.smegmatis_MC2_155      DPEAGIDFVNKLVTEHVKTRPGSGREATDVFLQGTGDVLISYENEAIYVE
TH_1447|M.thermoresistible__bu      DRQAGLDYVTRLVNEHIKLRPGSGREATDVFLQGSGDVLLAYENEAINAR
                                    . :**::::  ** **:* * **.*** :.* **:****::*****:   

Mb2422c|M.bovis_AF2122/97           RAGKPVQHVTPPQTFKIENPLAVVATSTHLGAATAFRNFQYTVQAQKLWA
Rv2400c|M.tuberculosis_H37Rv        RAGKPVQHVTPPQTFKIENPLAVVATSTHLGAATAFRNFQYTVQAQKLWA
MMAR_3718|M.marinum_M               RQGKRVQHVTPPQSFQIENPLAVVTTTAHLATATAFKNFQYTVEAQRLWA
MUL_3661|M.ulcerans_Agy99           RQGKRVQHVTPPQSFQIENPLAVVTTTAHLATATAFKNFQYTVEAQRLWA
MLBr_00615|M.leprae_Br4923          RQGKPVEHINPPVTFKIENPLAVVSTSAHLEVATAFKNFQYTTAAQGLWA
MAV_1782|M.avium_104                RAGKPVEHLNLAQTFKIDNPVAVVNTSPHLQAAVAFKNFQYTAAAQKVWA
MAB_1652|M.abscessus_ATCC_1997      SLGKPIEHVNVPITFKIENPVAVVSESLHVKKATEFKNFLYTPEAQRIWA
Mflv_2678|M.gilvum_PYR-GCK          -----LEHVNPAQTFKIENPTAVVNTSRHLDKAQAFVDFQFTPEGQKLWA
Mvan_3875|M.vanbaalenii_PYR-1       -----LEHVNPAQTFKIENPTAVVNTSQHPDQAQAFVNFQFTPEAQKLWA
MSMEG_4533|M.smegmatis_MC2_155      RQGKPVEHVNPPQTFKIENPVAVVNTTSHSEAANALKNFVFTPEGQKIWA
TH_1447|M.thermoresistible__bu      RQGHRFDYLTPPQTFKIENPVAVVTTSRHLDKATAFVNFQYTPEAQRLWA
                                         .:::. . :*:*:** ***  : *   *  : :* :*  .* :**

Mb2422c|M.bovis_AF2122/97           QAGFRPVDPAVAADFADLFPVPAKLWTIADLGGWGSVDPQLFDKATGSIT
Rv2400c|M.tuberculosis_H37Rv        QAGFRPVDPAVAADFADLFPVPAKLWTIADLGGWGSVDPQLFDKATGSIT
MMAR_3718|M.marinum_M               QAGFRPVDPAVVAEFRDQFPLPEKLWTIADLGGWDTVDPQLFDKGTGSIT
MUL_3661|M.ulcerans_Agy99           QAGFRPVDPAVVVEFRDQFPLPEKLWTIADLGGWDTVDPQLFDKGTGSIT
MLBr_00615|M.leprae_Br4923          QAGFRPVDPAVSADFSDQFPAPVKLWTIADLGGWSTVDPQLFDKNTGSIT
MAV_1782|M.avium_104                QAGFRPVDPAVAADFRDQYPVPAKLWTIADLGGWSAADPQLFDKNTGSIT
MAB_1652|M.abscessus_ATCC_1997      KTGFRPVDPGVAAEFASSFPVPSKLWTIKDLGGWKSVDKELFDKNDGSIT
Mflv_2678|M.gilvum_PYR-GCK          EAGFRPVDPAVQAEFADKFPAPEKLWTIDDLGGWKNVDTQLFDKDNGTIT
Mvan_3875|M.vanbaalenii_PYR-1       EANFRPVDPAVLAEFADKFPTPEKLWTIEDLGGWSKVDSELFDKENGTIT
MSMEG_4533|M.smegmatis_MC2_155      EAGFRPVDPAVAAEFAADFPAPEKLWTVDDLGGWDAVDPSLFDKDNGTIT
TH_1447|M.thermoresistible__bu      EAGFRPVDPAVAADFADQFPAPEKLWTIDDLGGWEKVDVELFNKDGGAIT
                                    ::.******.* .:*   :* * ****: *****  .* .**:*  *:**

Mb2422c|M.bovis_AF2122/97           KIYLRATG
Rv2400c|M.tuberculosis_H37Rv        KIYLRATG
MMAR_3718|M.marinum_M               NIYMQATG
MUL_3661|M.ulcerans_Agy99           NIYMQATG
MLBr_00615|M.leprae_Br4923          KVYMQATG
MAV_1782|M.avium_104                KIYTQATG
MAB_1652|M.abscessus_ATCC_1997      KIYKEATG
Mflv_2678|M.gilvum_PYR-GCK          KIYKQATG
Mvan_3875|M.vanbaalenii_PYR-1       KIYKQATG
MSMEG_4533|M.smegmatis_MC2_155      KIYKQATG
TH_1447|M.thermoresistible__bu      KIYIQATG
                                    ::* .***