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M. abscessus ATCC 19977 MAB_2705c (ileS)

annotation: isoleucyl-tRNA synthetase
coordinates: 2749099 - 2752275
length: 1058

DAYPRTDLGADQRSGSPNLPALEKQVLRYWDQDDTFRASIANRDGAPEYVFYDGPPFANGLPHYGHLLTG
YVKDIVPRYQTMRGYQVDRRFGWDTHGLPAELEVERQLGITDKSQIDSMGIAEFNDACRESVLRYTKEWR
EYVTRQARWVDFDNDYKTLDLTFMESVIWAFKQLWDKGLAYEGYRVLPYCWRDETPLSNHELRMDDDVYQ
SRQDPAVTVGYRIAGNEDSRWATLDGARLLIWTTTPWTLPSNLAVAVNPEVTYAVVKPEDSEDRYLLAQA
RVGAYARELGEEPTVLDTYTGAELLGLRYLPPFPYFQQDASPNAFTVLSGDYVTTDDGTGIVHMAPAYGE
EDKNVTDRAQITPVTPVDSKGRFDATVPDYEGQQVFDANAQIIKDLKNGTGAAGLNGAVLLRHETYDHSY
PHCWRCRNPLIYRAVSSWFIKVTEFRDRMVQLNEQITWYPEHVKHGQFGKWLEGARDWSVSRNRYWGSPI
PVWKSDDPAYPRIDVYGSLDELERDFGVRPTNLHRPYIDELTRPNPDDPTGKSTMRRIPDIFDVWFDSGS
MPYAQVHYPFENAEWFEKHFPADFIVEYIGQTRGWFYVMHVLATALFDRPAFRTCVSHGIVLGNDGQKMS
KSLRNYPDVNEVFDRDGSDAMRWFLMASPILRGGNLIVTEQGIREGVRQVILPLWNAWSFLQLYAPKPGT
WRTDSKQVLDRYILAKLAQLRDDLTTSMDDCDVSVACEQLRQFTDALTNWYVRRSRSRFWEEDADAIDTL
HTVLETTCRLAAPLLPMTTEVIWRGLTGERSVHLTDWVSESVLPADAALVAAMDEVRKVASTGSSLRKAK
KLRVRLPLLKLTVAVPDPKRLEPYTALIADELNVKSVELTDDIAAYGKFELTVNARVAGPRLGKDVQTVI
RAVKSGDWAQQADGTVVAAGITLREGEFDSKLVAAEPDSTAALPEGGGLVILDDTVTEELEAEGWARDLI
RELQDLRKSTGLEVSDRIEVVLEVPAVHRAWAERHRELISGEILATTLDIAEAGADTRTPATALSDGVRV
SLKKAAG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_2705cileS-100% (1058)isoleucyl-tRNA synthetase
M. abscessus ATCC 19977MAB_1603valS2e-5524.43% (831) valyl-tRNA synthetase
M. abscessus ATCC 19977MAB_1128c-1e-0523.78% (349) methionyl-tRNA synthetase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1563ileS0.077.04% (1054) isoleucyl-tRNA synthetase
M. gilvum PYR-GCKMflv_3644ileS0.077.42% (1054) isoleucyl-tRNA synthetase
M. tuberculosis H37RvRv1536ileS0.077.04% (1054) isoleucyl-tRNA synthetase
M. leprae Br4923MLBr_01195ileS0.075.21% (1065) isoleucyl-tRNA synthetase
M. marinum MMMAR_2356ileS0.076.76% (1063) isoleucyl-tRNA synthetase IleS
M. avium 104MAV_3235ileS0.078.94% (1040) isoleucyl-tRNA synthetase
M. smegmatis MC2 155MSMEG_3169ileS0.077.10% (1048) isoleucyl-tRNA synthetase
M. thermoresistible (build 8)TH_3715-0.076.15% (1065) PUTATIVE Isoleucyl-tRNA synthetase
M. ulcerans Agy99MUL_1532ileS0.076.20% (1063) isoleucyl-tRNA synthetase
M. vanbaalenii PYR-1Mvan_2769ileS0.077.72% (1037) isoleucyl-tRNA synthetase

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_2356|M.marinum_M               -----------------MTD--------STYPRSNLG--ADHRGGSPDFP
MUL_1532|M.ulcerans_Agy99           -----------------MTD--------STYPRSNLG--ADHRGGSPDFP
Mb1563|M.bovis_AF2122/97            -----------------MTD--------NAYP--------KLAGGAPDLP
Rv1536|M.tuberculosis_H37Rv         -----------------MTD--------NAYP--------KLAGGAPDLP
MLBr_01195|M.leprae_Br4923          -----------------MTN--------SAYPRTDLG--ADQRGGSPNFP
MAV_3235|M.avium_104                -----------------MTDNLGFQADREAQPADSVQTYPKPAGGAPDFP
Mflv_3644|M.gilvum_PYR-GCK          --------------------MAQETHDVTAYP--------KPTSGAPKFP
Mvan_2769|M.vanbaalenii_PYR-1       ---------------------------MTAYP--------KFTAGAPRFP
MSMEG_3169|M.smegmatis_MC2_155      ---------------------------MTAYP--------KP--AAPNFP
TH_3715|M.thermoresistible__bu      VVPRRSRYPARCRPRVLKTWAQENREIVTAYP--------KPSPGAPNFP
MAB_2705c|M.abscessus_ATCC_199      ---------------------------MDAYPRTDLG--ADQRSGSPNLP
                                                                 : *        .   .:* :*

MMAR_2356|M.marinum_M               ELETQVLDYWARDETFRASIERRDGAPEYVFYDGPPFANGLPHYGHLLTG
MUL_1532|M.ulcerans_Agy99           ELETQVLDYWARDETFRASIERRDGAPEYVFYDGPPFANGLPHYGHLLTG
Mb1563|M.bovis_AF2122/97            ALELEVLDYWSRDDTFRASIARRDGAPEYVFYDGPPFANGLPHYGHLLTG
Rv1536|M.tuberculosis_H37Rv         ALELEVLDYWSRDDTFRASIARRDGAPEYVFYDGPPFANGLPHYGHLLTG
MLBr_01195|M.leprae_Br4923          ALEAQVLDYWSNDDTFRASIARCDDAPEYVFYDGPPFANGLPHYGHLLTG
MAV_3235|M.avium_104                ALELEVLDYWARDDTFRASIARRDGAEEYVFYDGPPFANGLPHYGHLLTG
Mflv_3644|M.gilvum_PYR-GCK          ALEAEVLQYWDSDDTFRASIAQRDGAPEFVFYDGPPFANGLPHYGHLLTG
Mvan_2769|M.vanbaalenii_PYR-1       ALEADVLSYWDTDDTFRASIARREGAPEYVFYDGPPFANGLPHYGHLLTG
MSMEG_3169|M.smegmatis_MC2_155      ERELEVLDYWAKDDTFRASVERREGAEEYVFYDGPPFANGLPHYGHLLTG
TH_3715|M.thermoresistible__bu      ALEQEVLEYWSADDTFRASIERRADAPEYVFYDGPPFANGLPHYGHLLTG
MAB_2705c|M.abscessus_ATCC_199      ALEKQVLRYWDQDDTFRASIANRDGAPEYVFYDGPPFANGLPHYGHLLTG
                                      * :** **  *:*****: .  .* *:*********************

MMAR_2356|M.marinum_M               YVKDIVPRYRTMRGFKVERRFGWDTHGLPAELEVERQLGITDKSQIDAMG
MUL_1532|M.ulcerans_Agy99           YVKDIVPRYRTMRGFKVERRFGWDTHGLPAELEVERQLGITDKSQIDAMG
Mb1563|M.bovis_AF2122/97            YVKDIVPRYRTMRGYKVERRFGWDTHGLPAELEVERQLGITDKSQIEAMG
Rv1536|M.tuberculosis_H37Rv         YVKDIVPRYRTMRGYKVERRFGWDTHGLPAELEVERQLGITDKSQIEAMG
MLBr_01195|M.leprae_Br4923          YVKDIVPRYRTMCGYKVERRFGWDTHGLPAELEVERQLGITDKSQIDAMG
MAV_3235|M.avium_104                YVKDIVPRYRTMRGNKVERRFGWDTHGLPAELEVERQLGITDKSQIDDMG
Mflv_3644|M.gilvum_PYR-GCK          YVKDIVPRYRTMRGYKVERRFGWDTHGLPAELEVQRQLGITDKAQIEQMG
Mvan_2769|M.vanbaalenii_PYR-1       YVKDIVPRYRTMRGYKVERRFGWDTHGLPAELEVQRQLGITDKAQIEEMG
MSMEG_3169|M.smegmatis_MC2_155      YVKDIVPRYRTMRGYKVERRFGWDTHGLPAELEVQRQLDITDKSQIEEMG
TH_3715|M.thermoresistible__bu      YVKDIVPRYRTMRGYKVERRFGWDTHGLPAELEVQRQLGITDKAQIEQMG
MAB_2705c|M.abscessus_ATCC_199      YVKDIVPRYQTMRGYQVDRRFGWDTHGLPAELEVERQLGITDKSQIDSMG
                                    *********:** * :*:****************:***.****:**: **

MMAR_2356|M.marinum_M               IAAFNDACRASVLRYTDEWQQYVTRQARWVDFDNDYKTLDLGYMESVIWA
MUL_1532|M.ulcerans_Agy99           IAAFNDACRASVLRYTDEWQQYVTRQARWVDFDNDYKTVDLGYMESVIWA
Mb1563|M.bovis_AF2122/97            IAAFNDACRASVLRYTDEWQAYVTRQARWVDFDNDYKTLDLAYMESVIWA
Rv1536|M.tuberculosis_H37Rv         IAAFNDACRASVLRYTDEWQAYVTRQARWVDFDNDYKTLDLAYMESVIWA
MLBr_01195|M.leprae_Br4923          IAAFNEACRKSVLRYTEEWQAYVTRQARWVDFDNDYKTLDLSYMESVIWA
MAV_3235|M.avium_104                IAAFNDACRESVLRYTDEWRAYVTRQARWVDFDNDYKTLDLPYMESVIWA
Mflv_3644|M.gilvum_PYR-GCK          IEKFNDACRASVLKYTDEWRDYVTRQARWVDFDNDYKTLDIGFMESVIWV
Mvan_2769|M.vanbaalenii_PYR-1       IEKFNDACRESVLKYTNEWREYVTRQARWVDFDNDYKTLDIGFMESVIWV
MSMEG_3169|M.smegmatis_MC2_155      IEKFNDACRASVLKYTNEWQAYVTRQARWVDFDNDYKTLDLPFMESVIWA
TH_3715|M.thermoresistible__bu      IEKFNDACRASVLRYTKEWREYVTRQARWVDFDNDYKTLDLGYMESVIWA
MAB_2705c|M.abscessus_ATCC_199      IAEFNDACRESVLRYTKEWREYVTRQARWVDFDNDYKTLDLTFMESVIWA
                                    *  **:*** ***:**.**: *****************:*: :******.

MMAR_2356|M.marinum_M               FRQLWDKGLAYEGYRVLPYCWRDETPLSNHELRMDDDVYQSRQDPALTVG
MUL_1532|M.ulcerans_Agy99           FRQLWDKGLAYEGYRVLPYCWRDETPLSNHELRMDDDVYQSRQDPALTVG
Mb1563|M.bovis_AF2122/97            FKQLWDKGLAYEGYRVLPYCWRDETPLSNHELRMDDDVYQSRQDPAVTVG
Rv1536|M.tuberculosis_H37Rv         FKQLWDKGLAYEGYRVLPYCWRDETPLSNHELRMDDDVYQSRQDPAVTVG
MLBr_01195|M.leprae_Br4923          FKQLWDKGLAYESYRVLPYCWRDETPLSNHELRMDDDVYQSRQDPAVTLG
MAV_3235|M.avium_104                FKQLWDKGLAYEGYRVLPYCWRDETPLSNHELRMDDDVYQSRQDPALTVG
Mflv_3644|M.gilvum_PYR-GCK          FKQLWDKGLAYEGNRVLPYCWNDETPLSSHELRMDDDVYQNRQDPALTVG
Mvan_2769|M.vanbaalenii_PYR-1       FKQLWDKGLAYEGNRVLPYCWNDETPLSSHELRMDDDVYQNRQDPALTVG
MSMEG_3169|M.smegmatis_MC2_155      FKQLWDKGLAYEGNRVLPYCWNDETPLSSHELRMDDDVYQSRQDPALTVG
TH_3715|M.thermoresistible__bu      FKQLWDKGLAYEGIRVLPYCWNDETPLSSHELRMDDDVYQSRQDPAITVG
MAB_2705c|M.abscessus_ATCC_199      FKQLWDKGLAYEGYRVLPYCWRDETPLSNHELRMDDDVYQSRQDPAVTVG
                                    *:**********. *******.******.***********.*****:*:*

MMAR_2356|M.marinum_M               FKVVDGEP----------QGELAGAYLLVWTTTPWTLPSNLAVAVHPDVT
MUL_1532|M.ulcerans_Agy99           FKVVDGEP----------QGELAGAYLLVWTTTPWTLPSNLAVAVHPDVT
Mb1563|M.bovis_AF2122/97            FKVVGGQP----------DNGLDGAYLLVWTTTPWTLPSNLAVAVSPDIT
Rv1536|M.tuberculosis_H37Rv         FKVVGGQP----------DNGLDGAYLLVWTTTPWTLPSNLAVAVSPDIT
MLBr_01195|M.leprae_Br4923          FKVLGGD-----------DEDLVGAYLLVWTTTPWTLPSNLAVAVHPDVT
MAV_3235|M.avium_104                FKVVGGE--------------LDGAHLLIWTTTPWTLPSNLAVAVHPEVT
Mflv_3644|M.gilvum_PYR-GCK          FRISSG--------------ELEGAYLLVWTTTPWTLPSNQAVAVNPDVT
Mvan_2769|M.vanbaalenii_PYR-1       YRIVGGPADERSREERTAKSDLVGAYLLIWTTTPWTLPSNQAVAVNPEVT
MSMEG_3169|M.smegmatis_MC2_155      FRIDEG--------------PLTDSYLLIWTTTPWTLPSNQAVAVGPDIT
TH_3715|M.thermoresistible__bu      FRVPDG--------------PLAGSHLLIWTTTPWTLPSNQAVAVHPDVT
MAB_2705c|M.abscessus_ATCC_199      YRIAGNED--------SRWATLDGARLLIWTTTPWTLPSNLAVAVNPEVT
                                    :::  .               * .: **:*********** **** *::*

MMAR_2356|M.marinum_M               YVQVR--VGDRRLVLAEARLAAYTRELGEEPEVIGSYRGADLLGMRYLPP
MUL_1532|M.ulcerans_Agy99           YVQVR--VGDRRLVLAEARLAAYTRELGEEPEVIGSYRGADLLGIRYLPP
Mb1563|M.bovis_AF2122/97            YVQVQ--AGDRRFVLAEARLAAYARELGEEPVVLGTYRGAELLGTRYLPP
Rv1536|M.tuberculosis_H37Rv         YVQVQ--AGDRRFVLAEARLAAYARELGEEPVVLGTYRGAELLGTRYLPP
MLBr_01195|M.leprae_Br4923          YVDVR--AGDRRFVLAQARLTAYARELGDEPEVLATYRGADLLGRHYLPP
MAV_3235|M.avium_104                YVQVR--SGDRRFVLAQPRLAAYARELGPEPEILGSYRGAELLGTRYLPP
Mflv_3644|M.gilvum_PYR-GCK          YVVVE--SDGRRYVLAEARLAAYAREFGEEPAVVATYRGADLLDVGYVPP
Mvan_2769|M.vanbaalenii_PYR-1       YVVVE--ADGRRYVLAEARLGAYARELGEEPTVVATYTGRELLDLHYAPP
MSMEG_3169|M.smegmatis_MC2_155      YVHVEG-ADGRRYLLAEARLGAYARELGEEPKVLATFTGRDLLGTHYVPP
TH_3715|M.thermoresistible__bu      YVQVAA-PDGRRYVLAEARLAAYARELGEEPEVLARFPGSELVETRYLPP
MAB_2705c|M.abscessus_ATCC_199      YAVVKPEDSEDRYLLAQARVGAYARELGEEPTVLDTYTGAELLGLRYLPP
                                    *. *    .  * :**:.*: **:**:* ** ::  : * :*:   * **

MMAR_2356|M.marinum_M               FAYFMDSP--NAFAVLAGEFVTTEDGTGIVHMAPAYGEDDMAVTSPVGIE
MUL_1532|M.ulcerans_Agy99           FAYFMDSP--NAFAVLAGEFVTTEDGTGIVHMAPAYGEDDMAVTSPVGIE
Mb1563|M.bovis_AF2122/97            FAYFMDWP--NAFQVLAGDFVTTDDGTGIVHMAPAYGEDDMVVAEAVGIA
Rv1536|M.tuberculosis_H37Rv         FAYFMDWP--NAFQVLAGDFVTTDDGTGIVHMAPAYGEDDMVVAEAVGIA
MLBr_01195|M.leprae_Br4923          FQYFYESAR-NAFQVLPGDFVTTDDGTGIVHIAPAYGEDDMATADKVGIV
MAV_3235|M.avium_104                FPYFMDSP--NAFRVLAGEFVTTEDGTGIVHLAPAYGEDDMAVADAAGIA
Mflv_3644|M.gilvum_PYR-GCK          FPYFMDSP--NAFRVLPAEFVSTEDGTGLVHMSPAYGEDDMATAQAGGID
Mvan_2769|M.vanbaalenii_PYR-1       FPYFMDSP--NAFRVLPGEFVSTEDGTGLVHMSPAYGEDDMATAQAGGIE
MSMEG_3169|M.smegmatis_MC2_155      FPYFMGSA--NAFQVLAGDFVSTEDGTGIVHMAPAYGEDDKATADAADIV
TH_3715|M.thermoresistible__bu      FTYFADAA--NSFRVLPADFVSTEDGTGIVHMAPAYGEDDMDVAKAADIT
MAB_2705c|M.abscessus_ATCC_199      FPYFQQDASPNAFTVLSGDYVTTDDGTGIVHMAPAYGEEDKNVTDRAQIT
                                    * **   .  *:* **..::*:*:****:**::*****:*  .:.   * 

MMAR_2356|M.marinum_M               PVTPVDAKGRFDSSVPDYQGQHVFDANAQIIRDLKNQSGPAAANGAVLIR
MUL_1532|M.ulcerans_Agy99           PVTPVDAKGRFDSSVPDYQGQHVFDANAQIIRDLKNQSGPAAANGAVLIR
Mb1563|M.bovis_AF2122/97            PVTPVDSKGRFDVTVADYQGQHVFDANAQIVRDLKTQSGPAAVNGPVLIR
Rv1536|M.tuberculosis_H37Rv         PVTPVDSKGRFDVTVADYQGQHVFDANAQIVRDLKTQSGPAAVNGPVLIR
MLBr_01195|M.leprae_Br4923          PVTPVDSNGCFDATVPDYQGQHVFEANAQIIRDLKNQSGSAAVNGAVLLR
MAV_3235|M.avium_104                PVTPVDSNGRFDAAVPDYQGLNVFDANPQIIRDLKNGSGAAAANAPVLLR
Mflv_3644|M.gilvum_PYR-GCK          AVTPVDAKGRFDASVPDYAGQHVFDANPQIIRDLKNGTGAAATNGAVLLR
Mvan_2769|M.vanbaalenii_PYR-1       AVTPVDAKGRFDATVPDYAGQHVFDANPQIIRDLKNQSGPAQANGAVLLR
MSMEG_3169|M.smegmatis_MC2_155      AVTPVDSKGRFDESVPDYVGQHVFEANPQIIRDLKNGDGSAGANGAVVLR
TH_3715|M.thermoresistible__bu      AVTPVDAKGCFDASVPDYQGRHVFDANPQIIRDLKNQAGPAGHNGAVLLR
MAB_2705c|M.abscessus_ATCC_199      PVTPVDSKGRFDATVPDYEGQQVFDANAQIIKDLKNGTGAAGLNGAVLLR
                                    .*****::* ** :*.** * :**:**.**::***.  *.*  *..*::*

MMAR_2356|M.marinum_M               HETYEHPYPHCWRCRNPLIYRAVSSWFVTVTKFRERMVELNQQITWYPEH
MUL_1532|M.ulcerans_Agy99           HETYEHPYPHCWRCRNPLIYRAVSSWFVTVTKFRERMVELNQQITWCPEH
Mb1563|M.bovis_AF2122/97            HETYEHPYPHCWRCRNPLIYRSVSSWFVRVTDFRDRMVELNQQITWYPEH
Rv1536|M.tuberculosis_H37Rv         HETYEHPYPHCWRCRNPLIYRSVSSWFVRVTDFRDRMVELNQQITWYPEH
MLBr_01195|M.leprae_Br4923          HETYEHPYPHCWRCRNPLIYRAVSSWFVAVTEFRDRMVELNQQITWYPEH
MAV_3235|M.avium_104                HETYEHPYPHCWRCRNPLIYRAVSSWFVAVTRFRDRMVELNQQITWYPEH
Mflv_3644|M.gilvum_PYR-GCK          HDSYEHSYPHCWRCRNPLIYRAVSSWFVKVTQFRDRMVELNQEITWYPEH
Mvan_2769|M.vanbaalenii_PYR-1       HDTYEHSYPHCWRCRNPLIYRAVSSWFIKVTQFRDRMVELNQEITWYPEH
MSMEG_3169|M.smegmatis_MC2_155      HETYEHSYPHCWRCRNPLIYRAVSSWFVRVTEFRDRMVELNQQITWYPEH
TH_3715|M.thermoresistible__bu      HDTYEHSYPHCWRCRNPLIYRAVSSWFIKVTEFRDRMVELNQQITWYPGH
MAB_2705c|M.abscessus_ATCC_199      HETYDHSYPHCWRCRNPLIYRAVSSWFIKVTEFRDRMVQLNEQITWYPEH
                                    *::*:*.**************:*****: ** **:***:**::*** * *

MMAR_2356|M.marinum_M               VKDGQFGKWLQGARDWSISRNRYWGTPIPVWKSDDPAYPRIDVYGSLDEL
MUL_1532|M.ulcerans_Agy99           VKDGQFGKWLQGARDWSISRNRYWGTPIPVWKSDDPAYPRIDVYGSLDEL
Mb1563|M.bovis_AF2122/97            VKDGQFGKWLQGARDWSISRNRYWGTPIPVWKSDDPAYPRIDVYGSLDEL
Rv1536|M.tuberculosis_H37Rv         VKDGQFGKWLQGARDWSISRNRYWGTPIPVWKSDDPAYPRIDVYGSLDEL
MLBr_01195|M.leprae_Br4923          VKDGQFGKWLQGARDWSISRNRYWGTPIPVWKSDDPDYPRIDVYGSLDEL
MAV_3235|M.avium_104                VKDGQFGKWLAGARDWSISRNRYWGTPIPVWKSDDPAYPRIDVYGSLDEL
Mflv_3644|M.gilvum_PYR-GCK          VKDGQFGKWLQGARDWSISRNRYWGTPIPVWKSDDPAYPRIDVYGSLDEL
Mvan_2769|M.vanbaalenii_PYR-1       VKDGQFGKWLQGARDWSISRNRYWGTPIPVWKSDDPAYPRIDVYGSLDEL
MSMEG_3169|M.smegmatis_MC2_155      VKDGQFGKWLQGARDWSISRNRYWGTPIPVWKSDDPAYPRIDVYGSLDEL
TH_3715|M.thermoresistible__bu      VKDGQFGKWLANARDWSISRNRYWGTPIPVWVSDNPEYPRIDVYGSLDEL
MAB_2705c|M.abscessus_ATCC_199      VKHGQFGKWLEGARDWSVSRNRYWGSPIPVWKSDDPAYPRIDVYGSLDEL
                                    **.******* .*****:*******:***** **:* *************

MMAR_2356|M.marinum_M               ERDFGVRPTNLHRPYIDELTRPNPDDPTGQSTMRRIPDVLDVWFDSGSMP
MUL_1532|M.ulcerans_Agy99           ERDFGVRPINLHRPYIDELTRPNPDDPTGQSTMRRIPDVLDVWFDSGSMP
Mb1563|M.bovis_AF2122/97            ERDFGVRPANLHRPYIDELTRPNPDDPTGRSTMRRIPDVLDVWFDSGSMP
Rv1536|M.tuberculosis_H37Rv         ERDFGVRPANLHRPYIDELTRPNPDDPTGRSTMRRIPDVLDVWFDSGSMP
MLBr_01195|M.leprae_Br4923          ERDFGVRPTNLHRPYIDELTRPNPDDPTGLSTMRRIPDVFDVWFDSGSMP
MAV_3235|M.avium_104                ERDFGVRPDNLHRPYIDELTRPNPDDPSGRSTMRRIPDVLDVWFDSGSMP
Mflv_3644|M.gilvum_PYR-GCK          ERDFGVRPDNLHRPFIDELTRPNPDDPTGRSTMRRIEDVLDVWFDSGSMP
Mvan_2769|M.vanbaalenii_PYR-1       ERDFGVRPDNLHRPFIDELTRPNPDDPTGRSTMRRIEDVLDVWFDSGSMP
MSMEG_3169|M.smegmatis_MC2_155      ERDFGVRPDNLHRPFIDQLTRPNPDDPTGKSTMRRIEDVLDVWFDSGSMP
TH_3715|M.thermoresistible__bu      ERDFGVRPTDLHRPYIDELTRPNPDDPTGKSTMRRIPDVLDVWFDSGSMP
MAB_2705c|M.abscessus_ATCC_199      ERDFGVRPTNLHRPYIDELTRPNPDDPTGKSTMRRIPDIFDVWFDSGSMP
                                    ******** :****:**:*********:* ****** *::**********

MMAR_2356|M.marinum_M               YAQVHYPFENGDWFLGGAAGDAG----AHYPGDFIVEYIGQTRGWFYTLH
MUL_1532|M.ulcerans_Agy99           YAQVHYPFENGDWFLGGAAGDAG----AHYPGDFIVEYIGQTRGWFYTLH
Mb1563|M.bovis_AF2122/97            YAQVHYPFENLDWFQG------------HYPGDFIVEYIGQTRGWFYTLH
Rv1536|M.tuberculosis_H37Rv         YAQVHYPFENLDWFQG------------HYPGDFIVEYIGQTRGWFYTLH
MLBr_01195|M.leprae_Br4923          YAQVHYPFENDDWFDGFDSADSDKQVDAHYPGDFIVEYIGQARGWFYTLH
MAV_3235|M.avium_104                YAQVHYPFENRDWFET------------HYPGDFIVEYIGQTRGWFYTLH
Mflv_3644|M.gilvum_PYR-GCK          YGQVHYPFENQQWFE------------SHYPGDFIVEYIGQTRGWFYTLH
Mvan_2769|M.vanbaalenii_PYR-1       YGQVHYPFENSDWFD------------SHFPGDFIVEYIGQTRGWFYTLH
MSMEG_3169|M.smegmatis_MC2_155      YAQVHYPFENREWFDGASGEE------AHFPGDFIVEYIGQTRGWFYTLH
TH_3715|M.thermoresistible__bu      FAQVHYPFENADWFDGSDDQE------PHFPGDFIVEYIGQTRGWFYTLH
MAB_2705c|M.abscessus_ATCC_199      YAQVHYPFENAEWFEK------------HFPADFIVEYIGQTRGWFYVMH
                                    :.******** :**              *:*.*********:*****.:*

MMAR_2356|M.marinum_M               VLATALFDRPAFKTCVAHGIVLGSDGQKMSKSLRNYPDVAEVFHRDGSDA
MUL_1532|M.ulcerans_Agy99           VLATALFDRPAFKTCVAHGIVLGFDGQKMSKSLRNYPDVAEVFHRDGSDA
Mb1563|M.bovis_AF2122/97            VLATALFDRPAFKTCVAHGIVLGFDGQKMSKSLRNYPDVTEVFDRDGSDA
Rv1536|M.tuberculosis_H37Rv         VLATALFDRPAFKTCVAHGIVLGFDGQKMSKSLRNYPDVTEVFDRDGSDA
MLBr_01195|M.leprae_Br4923          VLATALFDRPAFKTCIAHGVVLGSNGQKMSKSLRNYPDVTEIFDRDGSDA
MAV_3235|M.avium_104                VLATALFDRPAFKTCVAHGIVLGSDGQKMSKSLRNYPDVSEVFDRDGSDA
Mflv_3644|M.gilvum_PYR-GCK          VLATALFDRPAFRTCVSHGIVLGNDGQKMSKSLRNYPDVSEVFDRDGSDA
Mvan_2769|M.vanbaalenii_PYR-1       ILATALFDRPAFRTCVSHGIVLGNDGQKMSKSLRNYPDVSEVFDRDGSDA
MSMEG_3169|M.smegmatis_MC2_155      VLATALFDKPAFKTCVSHGIVLGNDGQKMSKSLRNYPDVSEVFDRDGSDA
TH_3715|M.thermoresistible__bu      ILATALFDKPAFKTCVAHGIVLGNDGQKMSKSLRNYPDVTEVFDRDGSDA
MAB_2705c|M.abscessus_ATCC_199      VLATALFDRPAFRTCVSHGIVLGNDGQKMSKSLRNYPDVNEVFDRDGSDA
                                    :*******:***:**::**:*** :************** *:*.******

MMAR_2356|M.marinum_M               MRWFLMASPILRGGNLIVTEQGIREGVRQVLLPFWNAYSFLALYAPKVGT
MUL_1532|M.ulcerans_Agy99           MRWFLMASPILRGGNLIVTEQGIREGVRQVLLPFWNAYSFLALYAPKVGT
Mb1563|M.bovis_AF2122/97            MRWFLMASPILRGGNLIVTEQGIRDGVRQVLLPLWNTYSFLALYAPKVGT
Rv1536|M.tuberculosis_H37Rv         MRWFLMASPILRGGNLIVTEQGIRDGVRQVLLPLWNTYSFLALYAPKVGT
MLBr_01195|M.leprae_Br4923          MRWFLMASPILRGGNLIITEPGIREGMRQVLLPLWNAYSFLALYAPKIGT
MAV_3235|M.avium_104                MRWFLMASPILRGGNLIVTEQGIRDGVRQVLLPFWNAYSFLALYAPKVGT
Mflv_3644|M.gilvum_PYR-GCK          MRWFLMASPILRGGNLIVTEQGIREGVRQVLLPLWNAYTFLALYAPEKGT
Mvan_2769|M.vanbaalenii_PYR-1       MRWFLMASPILRGGNLIVTEQGIREGVRQVLLPLWNAYTFLALYAPSKGT
MSMEG_3169|M.smegmatis_MC2_155      MRWFLMASPILRGGNLIVTEQGIREGVRQVLLPLWNAYSFLALYAPEKGT
TH_3715|M.thermoresistible__bu      MRWFLMASPILRGGNLIVTEQGIRDGVRQVQLPLWNAYTFLALYAPKKGA
MAB_2705c|M.abscessus_ATCC_199      MRWFLMASPILRGGNLIVTEQGIREGVRQVILPLWNAWSFLQLYAPKPGT
                                    *****************:** ***:*:*** **:**:::** ****. *:

MMAR_2356|M.marinum_M               WRTDSDHVLDRYILAKLAVLRDDLTQAMEVCDISGACEQLRQFTEALTNW
MUL_1532|M.ulcerans_Agy99           WRTDSDHVLDRYILAKLAVLRDDLTQAMEVCDISGACEQLRQFTEALTNW
Mb1563|M.bovis_AF2122/97            WRVDSVHVLDRYILAKLAVLRDDLSESMEVYDIPGACEHLRQFTEALTNW
Rv1536|M.tuberculosis_H37Rv         WRVDSVHVLDRYILAKLAVLRDDLSESMEVYDIPGACEHLRQFTEALTNW
MLBr_01195|M.leprae_Br4923          WHTDVSHVLDRYILAKLAVLRDDLSQAMEVCDISGACEQLRQFTEPLTNW
MAV_3235|M.avium_104                WRTDSTQVLDRYILAKLAELRDDLTREMDACDISRACEQLRQFTEALTNW
Mflv_3644|M.gilvum_PYR-GCK          WRTDSTHVLDRYILAKLAQLRDDLTASLDVCDISQACDQLRQFTEALTNW
Mvan_2769|M.vanbaalenii_PYR-1       WRTDSEHVLDRYILAKLAVLRDDLTASLDVCDISQACDQLRQFTEALTNW
MSMEG_3169|M.smegmatis_MC2_155      WRTDSKNVLDRYILAKLAQLRDDLTSALDVCDISGACDELRQFAESLTNW
TH_3715|M.thermoresistible__bu      WRTDSRHVLDRYILAKLAALRDDLTDAMEVCDISGACEQLRQFIEALTNW
MAB_2705c|M.abscessus_ATCC_199      WRTDSKQVLDRYILAKLAQLRDDLTTSMDDCDVSVACEQLRQFTDALTNW
                                    *:.*  :*********** *****:  ::  *:. **:.**** :.****

MMAR_2356|M.marinum_M               YVRRSRSRFWQEDVDAIDTLHTVLEITARLAAPLLPLVTEVIWRGLTGER
MUL_1532|M.ulcerans_Agy99           YVRRSRSRFWQEDVDAIDTLHTVLEMTARLAAPLLPLVTEVIWRGLTGER
Mb1563|M.bovis_AF2122/97            YVRRSRSRFWAEDADAIDTLHTVLEVTTRLAAPLLPLITEIIWRGLTRER
Rv1536|M.tuberculosis_H37Rv         YVRRSRSRFWAEDADAIDTLHTVLEVTTRLAAPLLPLITEIIWRGLTRER
MLBr_01195|M.leprae_Br4923          YLRRSRARFWDEDVDAIDTLHTVLEVTARLAAPLLPLITEIIWRSVTGGR
MAV_3235|M.avium_104                YVRRSRSRFWSEDADAIDTLHTVLEVTARLAAPLLPSVTELVWRGLTGGR
Mflv_3644|M.gilvum_PYR-GCK          YVRRSRSRFWDEDADAIDTLHTVLEVTGRLAAPLLPLITEVIWRGVTGER
Mvan_2769|M.vanbaalenii_PYR-1       YVRRSRSRFWEEDADAIDTLHTVLEVTSRLAAPLLPLITEVIWRGVTGER
MSMEG_3169|M.smegmatis_MC2_155      YVRRSRSRFWDEDPDAIDTLHTVLEVTCRLAAPLLPLATEVIWRGLTGER
TH_3715|M.thermoresistible__bu      YVRRSRSRFWDEDPDAIDTLHTVLEVTGRLAAPLLPMTTEVIWRGITGER
MAB_2705c|M.abscessus_ATCC_199      YVRRSRSRFWEEDADAIDTLHTVLETTCRLAAPLLPMTTEVIWRGLTGER
                                    *:****:*** ** *********** * ********  **::**.:*  *

MMAR_2356|M.marinum_M               SVHLTDWPQAGEVPADAELVAAMDQVREVCSAASSLRKAKKLRVRLPLPK
MUL_1532|M.ulcerans_Agy99           SVHLTDWPQAGEVPADAELVAAMDQVREVCSAASSLRKAKKLRVRLPLPK
Mb1563|M.bovis_AF2122/97            SVHLTDWPAPDLLPSDADLVAAMDQVRDVCSAASSLRKAKKLRVRLPLPK
Rv1536|M.tuberculosis_H37Rv         SVHLTDWPAPDLLPSDADLVAAMDQVRDVCSAASSLRKAKKLRVRLPLPK
MLBr_01195|M.leprae_Br4923          SVHLTDWPQANQLPADPDLVAVMDQVRQVCSAASSLRKAKKLRVRLPLPK
MAV_3235|M.avium_104                SVHLTDWPRSGELPADPGLVAAMDQVREVCSAASSLRKAKKLRVRLPLPK
Mflv_3644|M.gilvum_PYR-GCK          SVHLTDWPEAGVLPADPQLVADMDLVRDVASAGSSLRKAQKLRVRLPLLK
Mvan_2769|M.vanbaalenii_PYR-1       SVHLTDWPEAGAVPADPQLVADMDLVREVASAGSSLRKAKKLRVRLPLLK
MSMEG_3169|M.smegmatis_MC2_155      SVHLTDWPEADVLPKDPDLVAAMDQVREVCSVGSSLRKAKKLRVRLPLPK
TH_3715|M.thermoresistible__bu      SVHLTDWPESGLLPSDPDLVEAMDQVRDVCSAASSLRKAKKLRVRLPLPK
MAB_2705c|M.abscessus_ATCC_199      SVHLTDWVSESVLPADAALVAAMDEVRKVASTGSSLRKAKKLRVRLPLLK
                                    *******   . :* *. **  ** **.*.*..******:******** *

MMAR_2356|M.marinum_M               LTVAVENPQALKPFTDLIADELNVKQVELTDAIGTYGRFELTVNARVAGP
MUL_1532|M.ulcerans_Agy99           LTVAVENPQALKPFTDLIADELNVKQIELADAIGTYGRFELTVNARVAGP
Mb1563|M.bovis_AF2122/97            LIVAVENPQLLRPFVDLIGDELNVKQVELTDAIDTYGRFELTVNARVAGP
Rv1536|M.tuberculosis_H37Rv         LIVAVENPQLLRPFVDLIGDELNVKQVELTDAIDTYGRFELTVNARVAGP
MLBr_01195|M.leprae_Br4923          LVVAVYNSQRLKPYIDLIGDELNVKQIELTDAIDTYGRFEFTVNARVAGP
MAV_3235|M.avium_104                LTVAVENPQHLAPFVDLIADELNVKSVELTDAIDTYGTFELTVNARVAGP
Mflv_3644|M.gilvum_PYR-GCK          LTVAVQDPGRLEPYRDLIADELNVKAVELTDDIAAHGRFELAVNARVAGP
Mvan_2769|M.vanbaalenii_PYR-1       LTVAVEDPTRLEPYRELIADELNVKSVELTDDIAAHGRFELTVNARVAGP
MSMEG_3169|M.smegmatis_MC2_155      LTVAVQDPDSLRPFADLIADELNVKAVELSDDVPAYGRFELAVNARVAGP
TH_3715|M.thermoresistible__bu      LTVGVDNPQRLEPFVDLIADELNVKSVELTDDIARYGRFELTVNARVAGP
MAB_2705c|M.abscessus_ATCC_199      LTVAVPDPKRLEPYTALIADELNVKSVELTDDIAAYGKFELTVNARVAGP
                                    * *.* :.  * *:  **.****** :**:* :  :* **::********

MMAR_2356|M.marinum_M               RLGKDVQAAIKAVKAGEGVVNSDGTLTAGPAVLQPEEYSSRLVAADP---
MUL_1532|M.ulcerans_Agy99           RLGKDVQAAIKAVKAGEGVVNSDGILTAGPAVLQPEEYSSRLVAADP---
Mb1563|M.bovis_AF2122/97            RLGKDVQAAIKAVKAGDGVINPDGTLLAGPAVLTADEYNSRLVAADP---
Rv1536|M.tuberculosis_H37Rv         RLGKDVQAAIKAVKAGDGVINPDGTLLAGPAVLTPDEYNSRLVAADP---
MLBr_01195|M.leprae_Br4923          RLGRDVQAAIKVVKAGEGVANPDGTLTAGPVVLQPDEYSSRLVAANP---
MAV_3235|M.avium_104                RLGKDVQAAIKAVKAGEGVVNADGTLTAGPAVLRPEEYSSRLVAADP---
Mflv_3644|M.gilvum_PYR-GCK          RIGRDVQAAIKAVKAGEAVVNDDGTLTAGPAVLLPEEFSSKLVAAEE---
Mvan_2769|M.vanbaalenii_PYR-1       RIGKDVQAAIKAVKAGEAVVNADGTLTAGPAVLQPEEYSSRLVAADP---
MSMEG_3169|M.smegmatis_MC2_155      RIGKDVQAAIKAVKAGEGVVNPDGTLTAGPVVLQPEEYTSKLVAADP---
TH_3715|M.thermoresistible__bu      RLGKDVQAAIKAVKAGEGVVNPDGTLTAGSVVLQPGEFSSRLVAADAPAD
MAB_2705c|M.abscessus_ATCC_199      RLGKDVQTVIRAVKSGDWAQQADGTVVAAGITLREGEFDSKLVAAEP---
                                    *:*:***:.*:.**:*: . : ** : *.  .*   *: *:****:    

MMAR_2356|M.marinum_M               --EFTAALPGGAGLVVLDGTVTPELEAEGWAKDRIRELQELRKSTGLDVS
MUL_1532|M.ulcerans_Agy99           --EFTAALPSGAGLVVLDGTVTPELEAEGWAKDRIRELQELRKSTGLDVS
Mb1563|M.bovis_AF2122/97            --ESTAALPDGAGLVVLDGTVTAELEAEGWAKDRIRELQELRKSTGLDVS
Rv1536|M.tuberculosis_H37Rv         --ESTAALPDGAGLVVLDGTVTAELEAEGWAKDRIRELQELRKSTGLDVS
MLBr_01195|M.leprae_Br4923          --EFTAELPDGSGLVVLDDTVTPELEAEGWAKDRIRELQELRKLIGLDVS
MAV_3235|M.avium_104                --EFTAALPNGAGLVVLDGTVTPELEAEGWAKDRIRELQELRKSTGLDVS
Mflv_3644|M.gilvum_PYR-GCK          --AFTAALPGGAGLVVLDGTVTPELEAEGWAKDRIRELQELRKSTGLDVS
Mvan_2769|M.vanbaalenii_PYR-1       --EWTAALPDGAGLVVLDGTVTPELEAEGWARDMIREIQEFRRQCELDIS
MSMEG_3169|M.smegmatis_MC2_155      --EWTAALPDGAGLVVLDGTVTEELEAEGWAKDRIRELQELRKSTGLEVS
TH_3715|M.thermoresistible__bu      EDRATAALPEGAGLVVLDCTVTPELEAEGWAKDRIRELQELRKSTGLDIS
MAB_2705c|M.abscessus_ATCC_199      --DSTAALPEGGGLVILDDTVTEELEAEGWARDLIRELQDLRKSTGLEVS
                                        ** ** *.***:** *** ********:* ***:*::*:   *::*

MMAR_2356|M.marinum_M               DRIQVLISVPGERAEWARTHRDLIAGEILATTFEFG---------EPDDG
MUL_1532|M.ulcerans_Agy99           DRIQVLISVPGERAEWARTHRDLIAGEILATTFEFG---------EPDDG
Mb1563|M.bovis_AF2122/97            DRIRVVMSVPAEREDWARTHRDLIAGEILATDFEFA---------DLADG
Rv1536|M.tuberculosis_H37Rv         DRIRVVMSVPAEREDWARTHRDLIAGEILATDFEFA---------DLADG
MLBr_01195|M.leprae_Br4923          DRIRVLMSVPAERADWARVHRDFIAREILATSFEFG---------EPADS
MAV_3235|M.avium_104                DRISVVMSVPAGRAEWAHTHRDLIAGEILATRFEFG---------EPADP
Mflv_3644|M.gilvum_PYR-GCK          DRISVVMSVPSTHQQWAQTHRDLIAGEILATSFEFG---------EPDGA
Mvan_2769|M.vanbaalenii_PYR-1       DRILLELGVSELPEGWQEGLKDLIANEVLALELTINPELNLKLKVEPDDG
MSMEG_3169|M.smegmatis_MC2_155      DRISVRISVPAEHEQWARTHRDLIAGEILATSFEFA---------EVTDG
TH_3715|M.thermoresistible__bu      DRISVVMSVPPQRQDWAERHRELIAGEILATSFEFGD--------PGESA
MAB_2705c|M.abscessus_ATCC_199      DRIEVVLEVPAVHRAWAERHRELISGEILATTLDIAEAG----ADTRTPA
                                    *** : : *.     * .  :::*: *:**  : :               

MMAR_2356|M.marinum_M               VEIGDGVRVAIAKSGGAGVSGREQA-------------
MUL_1532|M.ulcerans_Agy99           VEIGDGVRVAIAKSGGAGVSGREQA-------------
Mb1563|M.bovis_AF2122/97            VAIGDGVRVSIEKT------------------------
Rv1536|M.tuberculosis_H37Rv         VAIGDGVRVSIEKT------------------------
MLBr_01195|M.leprae_Br4923          VAIGDGVRVSLLKV------------------------
MAV_3235|M.avium_104                VAIGDGVRVSISKV------------------------
Mflv_3644|M.gilvum_PYR-GCK          TEIGDGVRVAIAKA------------------------
Mvan_2769|M.vanbaalenii_PYR-1       LDAQSGVVQATDDPNVFVGRVGRGYPVRLERVVAPSVH
MSMEG_3169|M.smegmatis_MC2_155      AEIGDGVRVEIAKV------------------------
TH_3715|M.thermoresistible__bu      AEIGDGVRVAIAKAV-----------------------
MAB_2705c|M.abscessus_ATCC_199      TALSDGVRVSLKKAAG----------------------
                                        .**     .